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Number of items: 360.
A
Aalto, AL;
Mohan, AK;
Schwintzer, L;
Kupka, S;
Kietz, C;
Walczak, H;
Broemer, M;
(2018)
M1-linked ubiquitination by LUBEL is required for inflammatory responses to oral infection in Drosophila.
Cell Death & Differentiation
10.1038/s41418-018-0164-x.
(In press).
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Abbosh, C;
Swanton, C;
Birkbak, NJ;
(2018)
Circulating tumor DNA analyses reveal novel resistance mechanisms to CDK inhibition in metastatic breast cancer.
Annals of Oncology
10.1093/annonc/mdy017.
(In press).
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Abdollah, MRA;
Carter, TJ;
Jones, C;
Kalber, TL;
Rajkumar, V;
Tolner, B;
Gruettner, C;
... Chester, KA; + view all
(2018)
Fucoidan Prolongs the Circulation Time of Dextran-Coated Iron Oxide Nanoparticles.
ACS Nano
, 12
(2)
pp. 1156-1169.
10.1021/acsnano.7b06734.
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Abdul-Aziz, AM;
Shafat, MS;
Sun, Y;
Marlein, CR;
Piddock, RE;
Robinson, SD;
Edwards, DR;
... Rushworth, SA; + view all
(2018)
HIF1α drives chemokine factor pro-tumoral signaling pathways in acute myeloid leukemia.
Oncogene
, 37
(20)
pp. 2676-2686.
10.1038/s41388-018-0151-1.
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Abou-Alfa, G;
Qin, S;
Ryoo, B-Y;
Lu, S-N;
Yen, C-J;
Feng, Y-H;
Lim, HY;
... Chen, L-T; + view all
(2018)
Phase III randomized study of second line ADI-PEG 20 plus best supportive care versus placebo plus best supportive care in patients with advanced hepatocellular carcinoma.
Annals of Oncology
, 29
(6)
pp. 1402-1408.
10.1093/annonc/mdy101.
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Abou-Alfa, GK;
Meyer, T;
Cheng, A-L;
El-Khoueiry, AB;
Rimassa, L;
Ryoo, B-Y;
Cicin, I;
... Kelley, RK; + view all
(2018)
Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma.
New England Journal of Medicine
, 379
(1)
pp. 54-63.
10.1056/NEJMoa1717002.
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Adams, R;
Brown, E;
Brown, L;
Butler, R;
Falk, S;
Fisher, D;
Kaplan, R;
... FOCUS4 Trial Investigators; + view all
(2018)
Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial.
The Lancet Gastroenterology & Hepatology
, 3
(3)
pp. 162-171.
10.1016/S2468-1253(17)30394-1.
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Agerbæk, MØ;
Bang-Christensen, SR;
Yang, M-H;
Clausen, TM;
Pereira, MA;
Sharma, S;
Ditlev, SB;
... Salanti, A; + view all
(2018)
The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner.
Nature Communications
, 9
(1)
, Article 3279. 10.1038/s41467-018-05793-2.
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Aguiar, P;
Azevedo, O;
Pinto, R;
Marino, J;
Cardoso, C;
Sousa, N;
Cunha, D;
... Ducla Soares, JL; + view all
(2018)
Biomarkers of Myocardial Fibrosis: Revealing the Natural History of Fibrogenesis in Fabry Disease Cardiomyopathy.
Journal of the American Heart Association
, 7
(6)
10.1161/JAHA.117.007124.
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Akintonde, A;
McClelland, J;
Grimes, H;
Moinuddin, S;
Sharma, RA;
Rit, S;
Thielemans, K;
(2018)
Data Driven Cone Beam CT Motion Management for Radiotherapy Application.
In:
Proceedings of 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC).
IEEE: Atlanta, GA, USA.
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Al Shareef, Zainab;
Kardooni, Hoda;
Murillo-Garzón, Virginia;
Domenici, Giacomo;
Stylianakis, Emmanouil;
Steel, Jennifer H;
Rabano, Miriam;
... Kypta, Robert M; + view all
(2018)
Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1.
Oncogene
, 37
pp. 5305-5324.
10.1038/s41388-018-0294-0.
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Alberro, JA;
Ballester, B;
Deulofeu, P;
Fabregas, R;
Fraile, M;
Gubern, JM;
Janer, J;
... Llombart, HA; + view all
(2018)
Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials.
The Lancet Oncology
, 19
(1)
pp. 27-39.
10.1016/S1470-2045(17)30777-5.
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Alexandrou, C;
Al-Aqbi, SS;
Higgins, JA;
Boyle, W;
Karmokar, A;
Andreadi, C;
Luo, J-L;
... Rufini, A; + view all
(2018)
Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes.
Scientific Reports
, 8
, Article 12096. 10.1038/s41598-018-30591-7.
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Alrifai, D;
Forster, MD;
Janes, SM;
(2018)
Emerging resistance pathways in lung cancer: what has ROS-1 taught us?
[Editorial comment].
Translational Lung Cancer Research
, 7
(Suppl 1)
S9-S12.
10.21037/tlcr.2017.11.13.
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Amos, R;
Bulbeck, H;
Burnet, N;
Crellin, A;
Eaton, D;
Evans, P;
Hall, E;
... Sharma, RA; + view all
(2018)
Proton Beam Therapy – the Challenges of Delivering High-quality Evidence of Clinical Benefit.
Clinical Oncology
, 30
(5)
10.1016/j.clon.2018.02.031.
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Anderson, ND;
de Borja, R;
Young, MD;
Fuligni, F;
Rosic, A;
Roberts, ND;
Hajjar, S;
... Shlien, A; + view all
(2018)
Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors.
Science
, 361
(6405)
10.1126/science.aam8419.
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Anderson, RA;
Remedios, R;
Kirkwood, AA;
Patrick, P;
Stevens, L;
Clifton-Hadley, L;
Roberts, T;
... Johnson, PWM; + view all
(2018)
Determinants of Ovarian Function After Response-adapted Therapy in Patients With Advanced Hodgkin's Lymphoma (RATHL): a Secondary Analysis of a Randomised Phase 3 Trial.
Lancet Oncology
, 19
(10)
pp. 1328-1337.
10.1016/S1470-2045(18)30500-X.
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Arends, M;
Biegstraaten, M;
Wanner, C;
Sirrs, S;
Mehta, A;
Elliott, PM;
Oder, D;
... Hollak, CEM; + view all
(2018)
Agalsidase alfa versus agalsidase beta for the treatment of Fabry disease: an international cohort study.
Journal of Medical Genetics
, 55
(5)
pp. 351-358.
10.1136/jmedgenet-2017-104863.
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Ariyaratne, Hemal;
(2018)
Dosimetric investigation of image-guided radiotherapy for prostate cancer using cone-beam computed tomography.
Doctoral thesis (M.D(Res)), UCL (University College London).
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Arkenau, H-T;
Italiano, A;
Mak, G;
Toulmonde, M;
Baird, RD;
Garcia-Corbacho, J;
Plummer, R;
... Spicer, J; + view all
(2018)
An extended phase Ib study of epertinib, an orally active reversible dual EGFR/HER2 tyrosine kinase inhibitor, in patients with solid tumours.
European Journal of Cancer
, 103
pp. 17-23.
10.1016/j.ejca.2018.07.134.
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Atkinson, S;
Marguerat, S;
Bitton, D;
Bachand, F;
Rodriguez-Lopez, M;
Rallis, C;
Lemay, J-F;
... Bähler, J; + view all
(2018)
Long noncoding RNA repertoire and targeting by nuclear exosome, cytoplasmic exonuclease, and RNAi in fission yeast.
RNA
, 24
(9)
pp. 1195-1213.
10.1261/rna.065524.118.
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Attard, G;
Borre, M;
Gurney, H;
Loriot, Y;
Andresen-Daniil, C;
Kalleda, R;
Trinh, P;
(2018)
Abiraterone Alone or in Combination With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer With Rising Prostate-Specific Antigen During Enzalutamide Treatment.
Journal of Clinical Oncology
, 36
(25)
pp. 2639-2646.
10.1200/JCO.2018.77.9827.
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Atzeni, A;
Jansen, M;
Ourselin, S;
Iglesias, JE;
(2018)
A probabilistic model combining deep learning and multi-atlas segmentation for semi-automated labelling of histology.
In: Frangi, AF and Schnabel, JA and Davatzikos, C and Alberola-López, C and Fichtinger, G, (eds.)
Medical Image Computing and Computer Assisted Intervention – MICCAI 2018: 21st International Conference, Proceedings, Part II.
(pp. pp. 219-227).
Springer: Cham, Switzerland.
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Auner, HW;
Yong, KL;
(2018)
More convenient proteasome inhibition for improved outcomes.
Lancet Oncology
, 19
(7)
pp. 856-858.
10.1016/S1470-2045(18)30411-X.
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B
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Backen, AC;
Lopes, A;
Wasan, H;
Palmer, DH;
Duggan, M;
Cunningham, D;
Anthoney, A;
... Valle, JW; + view all
(2018)
Circulating biomarkers during treatment in patients with advanced biliary tract cancer receiving cediranib in the UK ABC-03 trial.
British Journal of Cancer
, 119
pp. 27-35.
10.1038/s41416-018-0132-8.
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Baker, A-M;
Cross, W;
Curtius, K;
Al Bakir, I;
Choi, C-HR;
Davis, HL;
Temko, D;
... Graham, TA; + view all
(2018)
Evolutionary history of human colitis-associated colorectal cancer.
Gut
10.1136/gutjnl-2018-316191.
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Bakhoum, SF;
Ngo, B;
Laughney, AM;
Cavallo, J-A;
Murphy, CJ;
Ly, P;
Shah, P;
... Cantley, LC; + view all
(2018)
Chromosomal instability drives metastasis through a cytosolic DNA response.
Nature
, 553
(7689)
pp. 467-472.
10.1038/nature25432.
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Barata, PC;
De Liano, AG;
Mendiratta, P;
Crolley, V;
Szabados, B;
Morrison, L;
Wood, L;
... Rini, BI; + view all
(2018)
The efficacy of VEGFR TKI therapy after progression on immune combination therapy in metastatic renal cell carcinoma.
British Journal of Cancer
, 119
(2)
pp. 160-163.
10.1038/s41416-018-0104-z.
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Bazarbachi, A;
Boumendil, A;
Finel, H;
Mohty, M;
Castagna, L;
Peggs, KS;
Blaise, D;
... Sureda, A; + view all
(2018)
Brentuximab vedotin prior to allogeneic stem cell transplantation in Hodgkin lymphoma: a report from the EBMT Lymphoma Working Party.
British Journal of Haematology
, 181
(1)
pp. 86-96.
10.1111/bjh.15152.
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Beck, M;
Hughes, D;
Kampmann, C;
Pintos-Morell, G;
Ramaswami, U;
West, ML;
Giugliani, R;
(2018)
Long-term outcomes with agalsidase alfa enzyme replacement therapy: Analysis using deconstructed composite events.
Molecular Genetics and Metabolism Reports
, 14
pp. 31-35.
10.1016/j.ymgmr.2017.10.008.
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Beck, S;
(2018)
Getting up close and personal with UK genomics and beyond.
Genome Medicine
, 10
(1)
p. 38.
10.1186/s13073-018-0552-3.
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Beck, S;
Berner, AM;
Bignell, G;
Bond, M;
Callanan, MJ;
Chervova, O;
Conde, L;
... Wood, JN; + view all
(2018)
Personal Genome Project UK (PGP-UK): a research and citizen science hybrid project in support of personalized medicine.
BMC Medical Genomics
, 11
, Article 108. 10.1186/s12920-018-0423-1.
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Belderbos, BPSI;
de Wit, R;
Chien, C;
Mitselos, A;
Hellemans, P;
Jiao, J;
Yu, MK;
... Saad, F; + view all
(2018)
An open-label, multicenter, phase Ib study investigating the effect of apalutamide on ventricular repolarization in men with castration-resistant prostate cancer.
Cancer Chemotherapy and Pharmacology
, 82
(3)
pp. 457-468.
10.1007/s00280-018-3632-6.
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Berek, JS;
Matulonis, UA;
Peen, U;
Ghatage, P;
Mahner, S;
Redondo, A;
Lesoin, A;
... Mirza, MR; + view all
(2018)
Safety and dose modification for patients receiving niraparib.
Annals of Oncology
, 29
(8)
pp. 1784-1792.
10.1093/annonc/mdy181.
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Berry, V;
Ionides, ACW;
Pontikos, N;
Moghul, I;
Moore, AT;
Cheetham, ME;
Michaelides, M;
(2018)
Whole-genome sequencing reveals a recurrent missense mutation in the Connexin 46 (GJA3) gene causing autosomal-dominant lamellar cataract.
Eye
, 32
pp. 1661-1668.
10.1038/s41433-018-0154-8.
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Biegstraaten, M;
Cox, TM;
Belmatoug, N;
Berger, MG;
Collin-Histed, T;
Vom Dahl, S;
Di Rocco, M;
... Hollak, CE; + view all
(2018)
Management goals for type 1 Gaucher disease: An expert consensus document from the European working group on Gaucher disease.
Blood Cells, Molecules, and Diseases
, 68
pp. 203-208.
10.1016/j.bcmd.2016.10.008.
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Bird, TG;
Müller, M;
Boulter, L;
Vincent, DF;
Ridgway, RA;
Lopez-Guadamillas, E;
Lu, W-Y;
... Forbes, SJ; + view all
(2018)
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence.
Science Translational Medicine
, 10
(454)
, Article eaan1230. 10.1126/scitranslmed.aan1230.
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Birley, K;
Chester, K;
Anderson, J;
(2018)
Antibody based therapy for childhood solid cancers.
Current Opinion in Chemical Engineering
, 19
pp. 153-162.
10.1016/j.coche.2018.01.005.
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Biswas, S;
Quante, M;
Leedham, S;
Jansen, M;
(2018)
The metaplastic mosaic of Barrett's oesophagus.
Virchows Archiv
, 472
(1)
pp. 43-54.
10.1007/s00428-018-2317-1.
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Blas, P;
Tolner, B;
Ward, J;
Chester, K;
Hoare, M;
(2018)
The use of a surface active agent in the protection of a fusion protein during bioprocessing.
Biotechnology and Bioengineering
, 115
(11)
pp. 2760-2770.
10.1002/bit.26817.
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Böiers, C;
Richardson, SE;
Laycock, E;
Zriwil, A;
Turati, VA;
Brown, J;
Wray, JP;
... Enver, T; + view all
(2018)
A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1.
Developmental Cell
, 44
(3)
pp. 362-377.
10.1016/j.devcel.2017.12.005.
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Brandner, SGP;
Jaunmuktane, Z;
Capper, D;
Jones, DTW;
Sill, M;
Hovestadt, V;
Schrimpf, D;
... Pfister, SM; + view all
(2018)
DNA methylation-based classification of central nervous system tumours.
Nature. International Journal of Science
, 555
pp. 469-474.
10.1038/nature26000.
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Brizmohun, M;
Johnston, E;
Latifoltojar, A;
O'Callaghan, J;
Bonet-Carne, E;
Ferizi, U;
Yvernault, B;
... Punwani, S; + view all
(2018)
The intracellular component of VERDICT (Vascular, Extracellular, and Restricted Diffusion for Cytometry in Tumors) MRI distinguishes Gleason 4 pattern better than Apparent Diffusion Coefficient.
Presented at: Joint Annual Meeting ISMRM-ESMRMB 2018, Paris Expo Porte de Versailles, Paris, France.
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Brown, NF;
Carter, TJ;
Ottaviani, D;
Mulholland, P;
(2018)
Harnessing the immune system in glioblastoma.
British Journal of Cancer
, 119
(10)
pp. 1171-1181.
10.1038/s41416-018-0258-8.
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Brown, NF;
Williams, M;
Arkenau, H-T;
Fleming, RA;
Tolson, J;
Yan, L;
Zhang, J;
... Mulholland, P; + view all
(2018)
A study of the focal adhesion kinase inhibitor GSK2256098 in patients with recurrent glioblastoma with evaluation of tumor penetration of [¹¹C]GSK2256098.
Neuro-Oncology
, 20
(12)
pp. 1634-1642.
10.1093/neuonc/noy078.
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Burnett, AK;
Das Gupta, E;
Knapper, S;
Khwaja, A;
Sweeney, M;
Kjeldsen, L;
Hawkins, T;
... Russell, NH; + view all
(2018)
The Addition Of The MTORr Inhibitor, Everolimus, To Consolidation Therapy In Acute Myeloid Leukaemia: Experience From The UK NCRI AML17 Trial.
Haematologica
10.3324/haematol.2018.189514.
(In press).
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C
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Cappellini, MD;
Porter, JB;
Viprakasit, V;
Taher, AT;
(2018)
A paradigm shift on beta-thalassaemia treatment: How will we manage this old disease with new therapies?
Blood Reviews
, 32
(4)
pp. 300-311.
10.1016/j.blre.2018.02.001.
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Capper, D;
Engel, NW;
Stichel, D;
Lechner, M;
Gloess, S;
Schmid, S;
Koelsche, C;
... Schueller, U; + view all
(2018)
DNA methylation-based reclassification of olfactory neuroblastoma.
Acta Neuropathologica
, 136
(2)
pp. 255-271.
10.1007/s00401-018-1854-7.
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Carty, F;
Corbett, JM;
Cunha, JPMCM;
Reading, JL;
Tree, TIM;
Ting, AE;
Stubblefield, SR;
(2018)
Multipotent Adult Progenitor Cells Suppress T Cell Activation in In Vivo Models of Homeostatic Proliferation in a Prostaglandin E2-Dependent Manner.
Frontiers In Immunology
, 9
, Article 645. 10.3389/fimmu.2018.00645.
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Casali, PG;
Bielack, S;
Abecassis, N;
Aro, HT;
Bauer, S;
Biagini, R;
Bonvalot, S;
... Blay, JY; + view all
(2018)
Bone sarcomas: ESMO–PaedCan–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Annals of Oncology
, 29
(4)
pp. 79-95.
10.1093/annonc/mdy310.
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Catto, JWF;
Khetrapal, P;
Ambler, G;
Sarpong, R;
Khan, MS;
Tan, M;
Feber, A;
... Kelly, JD; + view all
(2018)
Robot-assisted radical cystectomy with intracorporeal urinary diversion versus open radical cystectomy (iROC): protocol for a randomised controlled trial with internal feasibility study.
BMJ Open
, 8
(8)
, Article e020500. 10.1136/bmjopen-2017-020500.
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Catto, JWF;
Khetrapal, P;
Ambler, G;
Sarpong, R;
Potyka, I;
Khan, S;
Tan, M;
... Kelly, JD; + view all
(2018)
Multidomain Quantitative Recovery Following Radical Cystectomy for Patients Within the Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion Versus Open Radical Cystectomy Randomised Controlled Trial: The First 30 Patients.
European Urology
, 74
(4)
pp. 531-534.
10.1016/j.eururo.2018.05.008.
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Cereser, B;
Jansen, M;
Austin, E;
Elia, G;
Mcfarlane, T;
van Deurzen, CH;
Sieuwerts, AM;
... Mcdonald, SA; + view all
(2018)
Analysis of clonal expansions through the normal and premalignant human breast epithelium reveals the presence of luminal stem cells.
Journal of Pathology
, 244
(1)
pp. 61-70.
10.1002/path.4989.
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Chakravarthy, A;
Furness, A;
Joshi, K;
Ghorani, E;
Ford, K;
Ward, MJ;
King, EV;
... Fenton, TR; + view all
(2018)
Author Correction: Pan-cancer deconvolution of tumour composition using DNA methylation.
[Corrigendum].
Nature Communications
, 9
, Article 4642. 10.1038/s41467-018-07155-4.
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Chakravarthy, A;
Furness, A;
Joshi, K;
Ghorani, E;
Ford, K;
Ward, MJ;
King, EV;
... Fenton, TR; + view all
(2018)
Pan-cancer deconvolution of tumour composition using DNA methylation.
Nature Communications
, 9
, Article 3220. 10.1038/s41467-018-05570-1.
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Chand, M;
Keller, DS;
Joshi, HM;
Devoto, L;
Rodriguez-Justo, M;
Cohen, R;
(2018)
Feasibility of fluorescence lymph node imaging in colon cancer: FLICC.
Techniques in Coloproctology
, 22
(4)
pp. 271-277.
10.1007/s10151-018-1773-6.
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Chapman, MA;
Sive, J;
Ambrose, J;
Roddie, C;
Counsell, N;
Lach, A;
Abbasian, M;
... Yong, K; + view all
(2018)
RNA-Seq of newly diagnosed patients in the PADIMAC study leads to a bortezomib/lenalidomide decision signature.
Blood
, 132
(20)
pp. 2154-2165.
10.1182/blood-2018-05-849893.
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Chen, L;
Esfandiari, A;
Reaves, W;
Vu, A;
Hogarty, MD;
Lunec, J;
Tweddle, DA;
(2018)
Characterisation of the p53 pathway in cell lines established from TH-MYCN transgenic mouse tumours.
International Journal of Oncology
, 52
(3)
pp. 967-977.
10.3892/ijo.2018.4261.
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Cheung, A;
Opzoomer, JW;
Ilieva, KM;
Gazinska, P;
Hoffmann, RM;
Mirza, H;
Marlow, R;
... Karagiannis, SN; + view all
(2018)
Anti-Folate Receptor alpha-directed Antibody Therapies Restrict the Growth of Triple Negative Breast Cancer.
Clinical Cancer Research
, 24
(20)
10.1158/1078-0432.CCR-18-0652.
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Chhetri, JB;
Drousioti, E;
Guerra-Assunção, JA;
Herrero, J;
Ooi, SKT;
(2018)
Generation of a Cancer Testis Antigen Mcherry Reporter Hct116 Colorectal Carcinoma Cell Line.
Heliyon
, 4
(10)
, Article e00858. 10.1016/j.heliyon.2018.e00858.
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Chia, KH;
Fukuda, T;
Sofyantoro, F;
Matsuda, T;
Amai, T;
Shiozaki, K;
(2018)
Ragulator and GATOR1 complexes promote fission yeast growth by attenuating TOR complex 1 through Rag GTPases.
eLife
, 6
, Article e30880. 10.7554/eLife.30880.
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Cho, S;
Zammarchi, F;
Williams, DG;
Havenith, CE;
Monks, NR;
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