Browse by UCL Department: listings for include files
- UCL (195369)
- UCL (195369)
- Provost and Vice Provost Offices (194144)
- School of Life and Medical Sciences (95338)
- Faculty of Brain Sciences (35355)
- UCL Queen Square Institute of Neurology (15180)
- UK Dementia Research Institute (272)
- UCL Queen Square Institute of Neurology (15180)
- Faculty of Brain Sciences (35355)
- School of Life and Medical Sciences (95338)
- Provost and Vice Provost Offices (194144)
- UCL (195369)
Number of items at this level: 272.
A
Ackels, T;
Erskine, A;
Dasgupta, D;
Marin, AC;
Warner, TPA;
Tootoonian, S;
Fukunaga, I;
... Schaefer, AT; + view all
(2021)
Fast odour dynamics are encoded in the olfactory system and guide behaviour.
Nature
, 593
pp. 558-563.
10.1038/s41586-021-03514-2.
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Agnew, T;
Goldsworthy, M;
Aguilar, C;
Morgan, A;
Simon, M;
Hilton, H;
Esapa, C;
... Cox, RD; + view all
(2018)
A Wars2 Mutant Mouse Model Displays OXPHOS Deficiencies and Activation of Tissue-Specific Stress Response Pathways.
Cell Reports
, 25
(12)
3315-3328.e6.
10.1016/j.celrep.2018.11.080.
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Ahlfors, H;
Anyanwu, N;
Pakanavicius, E;
Dinischiotu, N;
Lana-Elola, E;
Watson-Scales, S;
Tosh, J;
... Tybulewicz, VLJ; + view all
(2019)
Gene expression dysregulation domains are not a specific feature of Down syndrome.
Nature Communications
, 10
(1)
, Article 2489. 10.1038/s41467-019-10129-9.
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Ahmed, MM;
Dhanasekaran, AR;
Tong, S;
Wiseman, FK;
Fisher, EM;
Tybulewicz, VL;
Gardiner, KJ;
(2013)
Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain.
Human Molecular Genetics
, 22
(9)
1709 -1724.
10.1093/hmg/ddt017.
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Alić, I;
Goh, PA;
Murray, A;
Portelius, E;
Gkanatsiou, E;
Gough, G;
Mok, KY;
... Nižetić, D; + view all
(2020)
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain.
Molecular Psychiatry
10.1038/s41380-020-0806-5.
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Altendahl, M;
Cotter, DL;
Staffaroni, AM;
Wolf, A;
Mumford, P;
Cobigo, Y;
Casaletto, K;
... Walsh, CM; + view all
(2020)
REM sleep is associated with white matter integrity in cognitively healthy, older adults.
PLoS One
, 15
(7)
, Article e0235395. 10.1371/journal.pone.0235395.
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Arancibia-Carcamo, IL;
Attwell, D;
(2014)
The node of Ranvier in CNS pathology.
Acta Neuropathol
, 28
(8)
pp. 161-175.
10.1007/s00401-014-1305-z.
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Arancibia-Carcamo, IL;
Ford, MC;
Cossell, L;
Ishida, K;
Tohyama, K;
Attwell, D;
(2017)
Node of Ranvier length as a potential regulator of myelinated axon conduction speed.
eLife
, 6
, Article e23329. 10.7554/eLife.23329.
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Area-Gomez, E;
Larrea, D;
Pera, M;
Agrawal, RR;
Guilfoyle, DN;
Pirhaji, L;
Shannon, K;
... Nuriel, T; + view all
(2020)
APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice.
Scientific Reports
, 10
, Article 4277. 10.1038/s41598-020-61142-8.
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Attwell, D;
Madry, C;
Kyrargyri, V;
Arancibia-Carcamo, IL;
Jolivet, R;
Kohsaka, S;
Bryan, R;
(2018)
Microglial ramification, surveillance and interleukin-1beta release are regulated by the two-pore domain K+ channel THIK-1.
Neuron
, 97
(2)
pp. 299-312.
10.1016/j.neuron.2017.12.002.
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B
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Baligacs, Nora;
Albertini, Giulia;
Borrie, Sarah C;
Serneels, Lutgarde;
Pridans, Clare;
Balusu, Sriram;
De Strooper, Bart;
(2024)
Homeostatic microglia initially seed and
activated microglia later reshape amyloid
plaques in Alzheimer’s Disease.
Nature Communications
, 15
, Article 10634. 10.1038/s41467-024-54779-w.
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Balligand, Thomas;
Carpenet, Claire;
Olivé Palau, Sergi;
Jaspers, Tom;
Suresh, Pavana;
Liu, Xin;
Medhi, Himadri;
... Dewilde, Maarten; + view all
(2025)
A pair of congenic mice for imaging of transplants by positron emission tomography using anti-transferrin receptor nanobodies.
eLife
, 14
, Article RP104302. 10.7554/eLife.104302.
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Balusu, Sriram;
De Strooper, Bart;
(2024)
The necroptosis cell death pathway drives neurodegeneration in Alzheimer's disease.
Acta Neuropathologica
, 147
(1)
, Article 96. 10.1007/s00401-024-02747-5.
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Balusu, Sriram;
Horré, Katrien;
Thrupp, Nicola;
Craessaerts, Katleen;
Snellinx, An;
Serneels, Lutgarde;
T'Syen, Dries;
... De Strooper, Bart; + view all
(2023)
MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer’s disease.
Science
, 381
(6663)
pp. 1176-1182.
10.1126/science.abp9556.
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Barski, JJ;
Hartmann, J;
Rose, CR;
Hoebeek, F;
Morl, K;
Noll-Hussong, M;
De Zeeuw, CI;
... Meyer, M; + view all
(2003)
Calbindin in cerebellar Purkinje cells is a critical determinant of the precision of motor coordination.
Journal of Neuroscience
, 23
(8)
3469 - 3477.
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Bartels, T;
(2019)
A traffic jam leads to Lewy bodies.
Nature Neuroscience
, 22
pp. 1043-1045.
10.1038/s41593-019-0435-y.
|
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Bartels, T;
De Schepper, S;
Hong, S;
(2020)
Microglia modulate neurodegeneration in Alzheimer's and Parkinson's diseases.
Science
, 370
(6512)
pp. 66-69.
10.1126/science.abb8587.
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Bauza, Marius;
Krstulovic, Marino;
Krupic, Julija;
(2023)
Unsupervised, frequent and remote: A novel platform for personalised digital phenotyping of long-term memory in humans.
PLoS One
, 18
(4)
, Article e0284220. 10.1371/journal.pone.0284220.
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Birkle, Tim;
Brown, GC;
(2021)
I'm Infected, Eat Me! Innate Immunity Mediated by Live, Infected Cells Signaling To Be Phagocytosed.
Infection and Immunity
, 89
(5)
, Article e00476-20. 10.1128/iai.00476-20.
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Birkle, Timothy JY;
Brown, Guy C;
(2023)
Syk inhibitors protect against microglia-mediated neuronal loss in culture.
Frontiers in Aging Neuroscience
, 15
, Article 1120952. 10.3389/fnagi.2023.1120952.
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Blackburn, Emily Victoria;
(2025)
Investigating BDNF/TrkB signalling in neuronal models of Alzheimer's disease in Down syndrome.
Doctoral thesis (Ph.D), UCL(University College London).
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Blaudin de Thé, F-X;
Lassus, B;
Schaler, AW;
Fowler, SL;
Goulbourne, CN;
Jeggo, R;
Mannoury la Cour, C;
... Duff, KE; + view all
(2021)
P62 accumulates through neuroanatomical circuits in response to tauopathy propagation.
Acta Neuropathologica Communications
, 9
, Article 177. 10.1186/s40478-021-01280-w.
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Boorman, Luke W;
Harris, Samuel S;
Shabir, Osman;
Lee, Llywelyn;
Eyre, Beth;
Howarth, Clare;
Berwick, Jason;
(2023)
Bidirectional alterations in brain temperature profoundly modulate spatiotemporal neurovascular responses in-vivo.
Communications Biology
, 6
(1)
, Article 185. 10.1038/s42003-023-04542-6.
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Boyanova, Sevda;
Banks, Gareth;
Lipina, Tatiana V;
Bains, Rasneer Sonia;
Forrest, Hamish;
Stewart, Michelle;
Carcolé, Mireia;
... Wiseman, Frances K; + view all
(2025)
Multi-modal comparative phenotyping of knock-in mouse models of frontotemporal dementia/amyotrophic lateral sclerosis.
Disease Models & Mechanisms
, 18
(8)
, Article dmm052324. 10.1242/dmm.052324.
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Busche, MA;
(2019)
Tau suppresses neuronal activity in vivo, even before tangles form.
Brain
, 142
(4)
pp. 843-846.
10.1093/brain/awz060.
|
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Busche, MA;
Hyman, BT;
(2020)
Synergy between amyloid-β and tau in Alzheimer's disease.
Nature Neuroscience
, 23
pp. 1183-1193.
10.1038/s41593-020-0687-6.
|
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Busche, MA;
Wegmann, S;
Dujardin, S;
Commins, C;
Schiantarelli, J;
Klickstein, N;
Kamath, T;
... Hyman, BT; + view all
(2019)
Tau impairs neural circuits, dominating amyloid-beta effects, in Alzheimer models in vivo.
Nature Neuroscience
, 22
(1)
pp. 57-64.
10.1038/s41593-018-0289-8.
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C
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Calafate, S;
Özturan, G;
Thrupp, N;
Vanderlinden, J;
Santa-Marinha, L;
Morais-Ribeiro, R;
Ruggiero, A;
... de Wit, J; + view all
(2023)
Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer’s disease.
Nature Neuroscience
10.1038/s41593-023-01325-4.
(In press).
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Cannavo, C;
Cleverley, K;
Maduro, C;
Mumford, P;
Moulding, D;
Fisher, EMC;
Wiseman, FK;
(2022)
Endosomal structure and APP biology are not altered in a preclinical mouse cellular model of Down syndrome.
PLoS ONE
, 17
(5)
, Article e0262558. 10.1371/journal.pone.0262558.
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Cannavo, C;
Tosh, J;
Fisher, EMC;
Wiseman, FK;
(2020)
Using mouse models to understand Alzheimer's disease mechanisms in the context of trisomy of chromosome 21.
In: Dierssen, M, (ed.)
Progress in Brain Research.
(pp. 181-208).
Elsevier: London, UK.
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Capano, LS;
Sato, C;
Ficulle, E;
Yu, A;
Horie, K;
Kwon, JS;
Burbach, KF;
... Yoo, AS; + view all
(2022)
Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons.
Cell Stem Cell
, 29
(6)
918-932.e8.
10.1016/j.stem.2022.04.018.
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Chang, P;
Bush, D;
Schorge, S;
Good, M;
Canonica, T;
Shing, N;
Noy, S;
... Fisher, EMC; + view all
(2020)
Altered Hippocampal-Prefrontal Neural Dynamics in Mouse Models of Down Syndrome.
Cell Reports
, 30
(4)
1152-1163.e4.
10.1016/j.celrep.2019.12.065.
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Chaudhuri-Vayalambrone, Prannoy;
Rule, Michael Everett;
Bauza, Marius;
Krstulovic, Marino;
Kerekes, Pauline;
Burton, Stephen;
O'Leary, Timothy;
(2023)
Simultaneous representation of multiple time horizons by entorhinal grid cells and CA1 place cells.
Cell Reports
, 42
(7)
, Article 112716. 10.1016/j.celrep.2023.112716.
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Chelban, V;
Wilson, MP;
Warman Chardon, J;
Vandrovcova, J;
Zanetti, MN;
Zamba-Papanicolaou, E;
Efthymiou, S;
... SYNaPS Study Group, .; + view all
(2019)
PDXK mutations cause polyneuropathy responsive to PLP supplementation.
Annals of Neurology
10.1002/ana.25524.
(In press).
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Chen, S;
Acosta, D;
Li, L;
Liang, J;
Chang, Y;
Wang, C;
Fitzgerald, J;
... Fu, H; + view all
(2022)
Wolframin is a novel regulator of tau pathology and neurodegeneration.
Acta Neuropathologica
, 143
pp. 547-569.
10.1007/s00401-022-02417-4.
|
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Chen, S;
Chang, Y;
Li, L;
Acosta, D;
Li, Y;
Guo, Q;
Wang, C;
... Fu, H; + view all
(2022)
Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer’s disease.
Acta Neuropathologica Communications
, 10
(1)
, Article 188. 10.1186/s40478-022-01494-6.
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Chen, W-T;
Lu, A;
Craessaerts, K;
Pavie, B;
Sala Frigerio, C;
Corthout, N;
Qian, X;
... De Strooper, B; + view all
(2020)
Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer's Disease.
Cell
, 182
(4)
976-991.e19.
10.1016/j.cell.2020.06.038.
|
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Choong, XY;
(2015)
Investigating contributions of trisomy 21 in Down syndrome to Alzheimer disease phenotypes in a novel mouse cross.
Doctoral thesis , UCL (University College London).
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Cisneros, E;
di Marco, F;
Rueda-Carrasco, J;
Lillo, C;
Pereyra, G;
Martín-Bermejo, MJ;
Vargas, A;
... Bovolenta, P; + view all
(2020)
Sfrp1 deficiency makes retinal photoreceptors prone to degeneration.
Scientific Reports
, 10
(1)
, Article 5115. 10.1038/s41598-020-61970-8.
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Claes, C;
Van Den Daele, J;
Boon, R;
Schouteden, S;
Colombo, A;
Monasor, LS;
Fiers, M;
... Verfaillie, CM; + view all
(2018)
Human stem cell-derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2.
Alzheimer's & Dementia
10.1016/j.jalz.2018.09.006.
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Clarke-Williams, Charlie J;
Lopes-dos-Santos, Vítor;
Lefèvre, Laura;
Brizee, Demi;
Causse, Adrien A;
Rothaermel, Roman;
Hartwich, Katja;
... Dupret, David; + view all
(2024)
Coordinating brain-distributed network activities in memory resistant to extinction.
Cell
, 187
(2)
409-427.e19.
10.1016/j.cell.2023.12.018.
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Clelland, James D;
Read, Laura L;
Drouet, Valerie;
Kaon, Angela;
Kelly, Alexandra;
Duff, Karen E;
Nadrich, Robert H;
... Clelland, Catherine L; + view all
(2014)
Vitamin D insufficiency and schizophrenia risk: Evaluation of hyperprolinemia as a mediator of association.
Schizophrenia Research
, 156
(1)
pp. 15-22.
10.1016/j.schres.2014.03.017.
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Cleverley, K;
Lee, WC;
Mumford, P;
Collins, T;
Rickman, M;
Cunningham, TJ;
Cleak, J;
... Fisher, EMC; + view all
(2021)
A novel knockout mouse for the small EDRK-rich factor 2 (Serf2) showing developmental and other deficits.
Mammalian Genome
10.1007/s00335-021-09864-6.
(In press).
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Couedic, TL;
Caillon, R;
Rossant, F;
Joutel, A;
Urien, H;
Rajani, RM;
(2020)
Deep-learning based segmentation of challenging myelin sheaths.
In:
2020 Tenth International Conference on Image Processing Theory, Tools and Applications (IPTA).
IEEE: Paris, France.
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Croft, Cara L;
Paterno, Giavanna;
Vause, Ava R;
Rowe, Lyla A;
Ryu, Daniel H;
Goodwin, Marshall S;
Moran, Corey A;
... Golde, Todd E; + view all
(2022)
Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance.
npj Parkinson's Disease
, 8
, Article 173. 10.1038/s41531-022-00434-4.
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Crowley, Gerard;
Attwell, David;
Phatnani, Hemali;
Sontheimer, Harald;
Hong, Soyon;
(2024)
Glia in Neurodegenerative Disease.
Cold Spring Harbor perspectives in biology
a041375.
10.1101/cshperspect.a041375.
(In press).
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Cuypers, Marie-Lynn;
Jaspers, Tom;
Clerckx, Jarne;
Leekens, Simon;
Cawthorne, Christopher;
Bormans, Guy;
Cleeren, Frederik;
... Dewilde, Maarten; + view all
(2025)
Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein.
Fluids and Barriers of the CNS
, 22
(1)
, Article 11. 10.1186/s12987-025-00624-1.
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D
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Darricau, Morgane;
Dou, Changsong;
Kinet, Remi;
Zhu, Tao;
Zhou, Li;
Li, Xianglei;
Bedel, Aurelie;
... Planche, Vincent; + view all
(2023)
Tau seeds from Alzheimer's disease brains trigger tau spread in macaques while oligomeric-Aβ mediates pathology maturation.
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
10.1002/alz.13604.
(In press).
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Dasgupta, Debanjan;
Warner, Tom PA;
Erskine, Andrew;
Schaefer, Andreas T;
(2022)
Coupling of Mouse Olfactory Bulb Projection Neurons to Fluctuating Odor Pulses.
Journal of Neuroscience
, 42
(21)
pp. 4278-4296.
10.1523/JNEUROSCI.1422-21.2022.
|
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de Boni, Laura;
Wallis, Amber;
Hays Watson, Aurelia;
Ruiz-Riquelme, Alejandro;
Leyland, Louise-Ann;
Bourinaris, Thomas;
Hannaway, Naomi;
... Bartels, Tim; + view all
(2024)
Aggregation-resistant alpha-synuclein tetramers are reduced in the blood of Parkinson's patients.
EMBO Molecular Medicine
10.1038/s44321-024-00083-5.
(In press).
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De Boni, Laura;
Watson, Aurelia Hays;
Zaccagnini, Ludovica;
Wallis, Amber;
Zhelcheska, Kristina;
Kim, Nora;
Sanderson, John;
... Bartels, Tim; + view all
(2022)
Brain region-specific susceptibility of Lewy body pathology in synucleinopathies is governed by α-synuclein conformations.
Acta Neuropathologica
10.1007/s00401-022-02406-7.
(In press).
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De Schepper, Sebastiaan;
Ge, Judy Z;
Crowley, Gerard;
Ferreira, Laís SS;
Garceau, Dylan;
Toomey, Christina E;
Sokolova, Dimitra;
... Hong, Soyon; + view all
(2023)
Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease.
Nature Neuroscience
10.1038/s41593-023-01257-z.
(In press).
|
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De Schepper, S;
Crowley, G;
Hong, S;
(2021)
Understanding Microglial Diversity and Implications for Neuronal Function in Health and Disease.
Developmental Neurobiology
, 81
(5)
pp. 507-523.
10.1002/dneu.22777.
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De Schepper, S;
Verheijden, S;
Aguilera-Lizarraga, J;
Viola, MF;
Boesmans, W;
Stakenborg, N;
Voytyuk, I;
... Boeckxstaens, G; + view all
(2018)
Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis.
Cell
, 175
(2)
, Article e13. 10.1016/j.cell.2018.07.048.
|
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De Strooper, Bart;
Haass, Christian;
Hardy, John;
Zetterberg, Henrik;
(2025)
The regulatory rollercoaster continues—EMA refuses donanemab.
The Lancet
, 405
(10492)
pp. 1810-1812.
10.1016/S0140-6736(25)00833-5.
|
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De Strooper, Bart;
Haass, Christian;
Hardy, John;
Zetterberg, Henrik;
(2024)
Divisions over the regulation of lecanemab.
The Lancet
, 404
(10468)
pp. 2160-2161.
10.1016/S0140-6736(24)02513-3.
|
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De Strooper, Bart;
Karran, Eric;
(2024)
New precision medicine avenues to the prevention of Alzheimer's disease from insights into the structure and function of γ-secretases.
The EMBO Journal
10.1038/s44318-024-00057-w.
(In press).
|
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De Strooper, Bart;
Scheltens, Philip;
Salloway, Stephen;
(2025)
Breaking Barriers: Delivering Therapeutics to the Brain in Alzheimer’s
Disease.
The Journal of Prevention of Alzheimer's Disease
, 12
(7)
, Article 100229. 10.1016/j.tjpad.2025.100229.
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Delabar, JM;
Allinquant, B;
Bianchi, D;
Blumenthal, T;
Dekker, A;
Edgin, J;
O'Bryan, J;
... Busciglio, J; + view all
(2016)
Changing Paradigms in Down Syndrome: The First International Conference of the Trisomy 21 Research Society.
Molecular Syndromology
, 7
(5)
pp. 251-261.
10.1159/000449049.
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Dierssen, M;
Herault, Y;
Helguera, P;
Martinez de Lagran, M;
Vazquez, A;
Christian, B;
Carmona-Iragui, M;
... Bhattacharyya, A; + view all
(2021)
Building the Future Therapies for Down Syndrome: The Third International Conference of the T21 Research Society.
Molecular Syndromology
10.1159/000514437.
(In press).
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Dorion, Marie-France;
Yaqubi, Moein;
Senkevich, Konstantin;
Kieran, Nicholas W;
MacDonald, Adam;
Chen, Carol X-Q;
Luo, Wen;
... Healy, Luke M; + view all
(2023)
MerTK is a mediator of alpha-synuclein fibril uptake by human microglia.
Brain
, Article awad298,. 10.1093/brain/awad298.
(In press).
|
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Duggan, Michael R;
Gomez, Gabriela T;
Joynes, Cassandra M;
Bilgel, Murat;
Chen, Jingsha;
Fattorelli, Nicola;
Hohman, Timothy J;
... Walker, Keenan A; + view all
(2024)
Proteome-wide analysis identifies plasma immune regulators of amyloid-beta progression.
Brain, Behavior, and Immunity
, 120
pp. 604-619.
10.1016/j.bbi.2024.07.002.
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E
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Erkert, Lena;
Gamez-Belmonte, Reyes;
Kabisch, Melanie;
Schödel, Lena;
Patankar, Jay V;
Gonzalez-Acera, Miguel;
Mahapatro, Mousumi;
... Becker, Christoph; + view all
(2024)
Alzheimer's disease-related presenilins are key to intestinal epithelial cell function and gut immune homoeostasis.
Gut
10.1136/gutjnl-2023-331622.
(In press).
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Espuny-Camacho, I;
Arranz, AM;
Fiers, M;
Snellinx, A;
Ando, K;
Munck, S;
Bonnefont, J;
... De Strooper, B; + view all
(2017)
Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.
Neutron
, 93
(5)
, Article e8. 10.1016/j.neuron.2017.02.001.
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F
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Fa, M;
Puzzo, D;
Piacentini, R;
Staniszewski, A;
Zhang, H;
Baltrons, MA;
Li Puma, DD;
... Arancio, O; + view all
(2016)
Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory.
Scientific Reports
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