Guerrero, Ana;
(2023)
Nucleosome disruption by 5-bromodeoxyuridine leads to senescence.
The FEBS Journal
, 290
(3)
pp. 684-687.
10.1111/febs.16630.
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Abstract
5-Bromodeoxyuridine (BrdU) exposure leads to senescence, but the mechanistic details remain elusive. In this issue, En A et al. unveil a role of the HBR domain in histone H2B as a potential mediator of the effects of BrdU both in yeast and in human cells. Comment on: https://doi.org/10.1111/febs.16584.
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