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Number of items: 210.

Article

Abbosh, C; Hodgson, D; Doherty, GJ; Gale, D; Black, JRM; Horn, L; Reis-Filho, JS; Abbosh, C; Hodgson, D; Doherty, GJ; Gale, D; Black, JRM; Horn, L; Reis-Filho, JS; Swanton, C; - view fewer (2024) Implementing circulating tumor DNA as a prognostic biomarker in resectable non-small cell lung cancer. Trends in Cancer , 10 (7) pp. 643-654. 10.1016/j.trecan.2024.04.004.

Abbosh, C; Swanton, C; (2021) ctDNA: An emerging neoadjuvant biomarker in resectable solid tumors. PLoS Medicine , 18 (10) , Article e1003771. 10.1371/journal.pmed.1003771.

Abbosh, Christopher; Frankell, Alexander M; Harrison, Thomas; Kisistok, Judit; Garnett, Aaron; Johnson, Laura; Veeriah, Selvaraju; ... Swanton, Charles; + view all Abbosh, Christopher; Frankell, Alexander M; Harrison, Thomas; Kisistok, Judit; Garnett, Aaron; Johnson, Laura; Veeriah, Selvaraju; Moreau, Mike; Chesh, Adrian; Chaunzwa, Tafadzwa L; Weiss, Jakob; Schroeder, Morgan R; Ward, Sophia; Grigoriadis, Kristiana; Shahpurwalla, Aamir; Litchfield, Kevin; Puttick, Clare; Biswas, Dhruva; Karasaki, Takahiro; Black, James RM; Martínez-Ruiz, Carlos; Bakir, Maise Al; Pich, Oriol; Watkins, Thomas BK; Lim, Emilia L; Huebner, Ariana; Moore, David A; Godin-Heymann, Nadia; L'Hernault, Anne; Bye, Hannah; Odell, Aaron; Roberts, Paula; Gomes, Fabio; Patel, Akshay J; Manzano, Elizabeth; Hiley, Crispin T; Carey, Nicolas; Riley, Joan; Cook, Daniel E; Hodgson, Darren; Stetson, Daniel; Barrett, J Carl; Kortlever, Roderik M; Evan, Gerard I; Hackshaw, Allan; Daber, Robert D; Shaw, Jacqui A; Aerts, Hugo JWL; Licon, Abel; Stahl, Josh; Jamal-Hanjani, Mariam; TRACERx, Consortium; Birkbak, Nicolai J; McGranahan, Nicholas; Swanton, Charles; - view fewer (2023) Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA. Nature , 616 (7957) pp. 553-562. 10.1038/s41586-023-05776-4.

Abbosh, C; Birkbak, NJ; Wilson, GA; Jamal-Hanjani, M; Constantin, T; Salari, R; Le Quesne, J; ... Dessimoz, C; + view all Abbosh, C; Birkbak, NJ; Wilson, GA; Jamal-Hanjani, M; Constantin, T; Salari, R; Le Quesne, J; Moore, DA; Veeriah, S; Rosenthal, R; Marafioti, T; Kirkizlar, E; Watkins, TBK; McGranahan, N; Ward, S; Martinson, L; Riley, J; Fraioli, F; Al Bakir, M; Gronroos, E; Zambrana, F; Endozo, R; Bi, WL; Fennessy, FM; Sponer, N; Johnson, D; Laycock, J; Shafi, S; Czyzewska-Khan, J; Rowan, A; Chambers, T; Matthews, N; Turajlic, S; Hiley, C; Lee, SM; Forster, MD; Ahmad, T; Falzon, M; Borg, E; Lawrence, D; Hayward, M; Kolvekar, S; Panagiotopoulos, N; Janes, SM; Thakrar, R; Ahmed, A; Blackhall, F; Summers, Y; Hafez, D; Naik, A; Ganguly, A; Kareht, S; Shah, R; Joseph, L; Quinn, AM; Crosbie, PA; Naidu, B; Middleton, G; Langman, G; Trotter, S; Nicolson, M; Remmen, H; Kerr, K; Chetty, M; Gomersall, L; Fennell, DA; Nakas, A; Rathinam, S; Anand, G; Khan, S; Russell, P; Ezhil, V; Ismail, B; Irvin-Sellers, M; Prakash, V; Lester, JF; Kornaszewska, M; Attanoos, R; Adams, H; Davies, H; Oukrif, D; Akarca, AU; Hartley, JA; Lowe, HL; Lock, S; Iles, N; Bell, H; Ngai, Y; Elgar, G; Szallasi, Z; Schwarz, RF; Herrero, J; Stewart, A; Quezada, SA; Peggs, KS; Van Loo, P; Dive, C; Lin, CJ; Rabinowitz, M; Aerts, HJWL; Hackshaw, A; Shaw, JA; Zimmermann, BG; Swanton, C; Jamal-Hanjani, M; Abbosh, C; Veeriah, S; Shafi, S; Czyzewska-Khan, J; Johnson, D; Laycock, J; Bosshard-Carter, L; Goh, G; Rosenthal, R; Gorman, P; Murugaesu, N; Hynds, RE; Wilson, GA; Birkbak, NJ; Watkins, TBK; McGranahan, N; Horswell, S; Al Bakir, M; Gronroos, E; Mitter, R; Escudero, M; Stewart, A; Van Loo, P; Rowan, A; Xu, H; Turajlic, S; Hiley, C; Goldman, J; Stone, RK; Denner, T; Matthews, N; Elgar, G; Ward, S; Biggs, J; Costa, M; Begum, S; Phillimore, B; Chambers, T; Nye, E; Graca, S; Joshi, K; Furness, A; Ben Aissa, A; Wong, YNS; Georgiou, A; Quezada, SA; Peggs, KS; Hartley, JA; Lowe, HL; Herrero, J; Lawrence, D; Hayward, M; Panagiotopoulos, N; Kolvekar, S; Falzon, M; Borg, E; Marafioti, T; Simeon, C; Hector, G; Smith, A; Aranda, M; Novelli, M; Oukrif, D; Akarca, AU; Janes, SM; Thakrar, R; Forster, MD; Ahmad, T; Lee, SM; Papadatos-Pastos, D; Carnell, D; Mendes, R; George, J; Navani, N; Ahmed, A; Taylor, M; Choudhary, J; Summers, Y; Califano, R; Taylor, P; Shah, R; Krysiak, P; Rammohan, K; Fontaine, E; Booton, R; Evison, M; Crosbie, PA; Moss, S; Idries, F; Joseph, L; Bishop, P; Chaturvedi, A; Quinn, AM; Doran, H; Leek, A; Harrison, P; Moore, K; Waddington, R; Novasio, J; Blackhall, F; Rogan, J; Smith, E; Dive, C; Tugwood, J; Brady, G; Rothwell, DG; Chemi, F; Pierce, J; Gulati, S; Naidu, B; Langman, G; Trotter, S; Bellamy, M; Bancroft, H; Kerr, A; Kadiri, S; Webb, J; Middleton, G; Djearaman, M; Fennell, DA; Shaw, JA; Le Quesne, J; Moore, DA; Thomas, A; Walter, H; Riley, J; Martinson, L; Nakas, A; Rathinam, S; Monteiro, W; Marshall, H; Nelson, L; Bennett, J; Primrose, L; Anand, G; Khan, S; Amadi, A; Nicolson, M; Kerr, K; Palmer, S; Remmen, H; Miller, J; Buchan, K; Chetty, M; Gomersall, L; Lester, JF; Edwards, A; Morgan, F; Adams, H; Davies, H; Kornaszewska, M; Attanoos, R; Lock, S; Verjee, A; MacKenzie, M; Wilcox, M; Bell, H; Iles, N; Hackshaw, A; Ngai, Y; Smith, S; Gower, N; Ottensmeier, C; Chee, S; Johnson, B; Alzetani, A; Shaw, E; Lim, E; De Sousa, P; Barbosa, MT; Bowman, A; Jordan, S; Rice, A; Raubenheimer, H; Proli, C; Cufari, ME; Ronquillo, JC; Kwayie, A; Bhayani, H; Hamilton, M; Bakar, Y; Mensah, N; Ambrose, L; Devaraj, A; Buderi, S; Finch, J; Azcarate, L; Chavan, H; Green, S; Mashinga, H; Nicholson, AG; Lau, K; Sheaff, M; Schmid, P; Conibear, J; Ezhil, V; Ismail, B; Irvin-Sellers, M; Prakash, V; Russell, P; Light, T; Horey, T; Danson, S; Bury, J; Edwards, J; Hill, J; Matthews, S; Kitsanta, Y; Suvarna, K; Fisher, P; Keerio, AD; Shackcloth, M; Gosney, J; Postmus, P; Feeney, S; Asante-Siaw, J; Constantin, T; Salari, R; Sponer, N; Naik, A; Zimmermann, BG; Rabinowitz, M; Aerts, HJWL; Dentro, S; Dessimoz, C; - view fewer (2017) Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution. Nature , 545 pp. 446-451. 10.1038/nature22364.

Abbosh, C; Swanton, C; Birkbak, NJ; (2018) Circulating tumor DNA analyses reveal novel resistance mechanisms to CDK inhibition in metastatic breast cancer. Annals of Oncology 10.1093/annonc/mdy017. (In press).

Abbosh, C; Venkatesan, S; Janes, SM; Fitzgerald, RC; Swanton, C; (2017) Evolutionary dynamics in pre-invasive neoplasia. Current Opinion in System Biology , 2 pp. 1-8. 10.1016/j.coisb.2017.02.009.

AbdulJabbar, K; Raza, SEA; Rosenthal, R; Jamal-Hanjani, M; Veeriah, S; Akarca, A; Lund, T; ... Yuan, Y; + view all AbdulJabbar, K; Raza, SEA; Rosenthal, R; Jamal-Hanjani, M; Veeriah, S; Akarca, A; Lund, T; Moore, DA; Salgado, R; Al Bakir, M; Zapata, L; Hiley, CT; Officer, L; Sereno, M; Smith, CR; Loi, S; Hackshaw, A; Marafioti, T; Quezada, SA; McGranahan, N; Le Quesne, J; Swanton, C; Yuan, Y; - view fewer (2020) Geospatial immune variability illuminates differential evolution of lung adenocarcinoma. Nature Medicine , 26 pp. 1054-1062. 10.1038/s41591-020-0900-x.

Aitken, J; Ambrose, K; Barrell, S; Beale, R; Bineva-Todd, G; Biswas, D; Byrne, R; ... Wu, M; + view all Aitken, J; Ambrose, K; Barrell, S; Beale, R; Bineva-Todd, G; Biswas, D; Byrne, R; Caidan, S; Cherepanov, P; Churchward, L; Clark, G; Crawford, M; Cubitt, L; Dearing, V; Earl, C; Edwards, A; Ekin, C; Fidanis, E; Gaiba, A; Gamblin, S; Gandhi, S; Goldman, J; Goldstone, R; Grant, PR; Greco, M; Heaney, J; Hindmarsh, S; Houlihan, CF; Howell, M; Hubank, M; Hughes, D; Instrell, R; Jackson, D; Jamal-Hanjani, M; Jiang, M; Johnson, M; Jones, L; Kanu, N; Kassiotis, G; Kirk, S; Kjaer, S; Levett, A; Levett, L; Levi, M; Lu, W-T; MacRae, JI; Matthews, J; McCoy, LE; Moore, C; Moore, D; Nastouli, E; Nicod, J; Nightingale, L; Olsen, J; O'Reilly, N; Pabari, A; Papayannopoulos, V; Patel, N; Peat, N; Pollitt, M; Ratcliffe, P; Sousa, C; Rosa, A; Rosenthal, R; Roustan, C; Rowan, A; Shin, GY; Snell, DM; Song, O-R; Spyer, MJ; Strange, A; Swanton, C; Turner, JMA; Turner, M; Wack, A; Walker, PA; Ward, S; Wong, WK; Wright, J; Wu, M; - view fewer (2020) Scalable and robust SARS-CoV-2 testing in an academic center. Nature Biotechnology , 38 (8) pp. 927-931. 10.1038/s41587-020-0588-y.

Al Bakir, Maise; Huebner, Ariana; Martínez-Ruiz, Carlos; Grigoriadis, Kristiana; Watkins, Thomas BK; Pich, Oriol; Moore, David A; ... Swanton, Charles; + view all Al Bakir, Maise; Huebner, Ariana; Martínez-Ruiz, Carlos; Grigoriadis, Kristiana; Watkins, Thomas BK; Pich, Oriol; Moore, David A; Veeriah, Selvaraju; Ward, Sophia; Laycock, Joanne; Johnson, Diana; Rowan, Andrew; Razaq, Maryam; Akther, Mita; Naceur-Lombardelli, Cristina; Prymas, Paulina; Toncheva, Antonia; Hessey, Sonya; Dietzen, Michelle; Colliver, Emma; Frankell, Alexander M; Bunkum, Abigail; Lim, Emilia L; Karasaki, Takahiro; Abbosh, Christopher; Hiley, Crispin T; Hill, Mark S; Cook, Daniel E; Wilson, Gareth A; Salgado, Roberto; Nye, Emma; Stone, Richard Kevin; Fennell, Dean A; Price, Gillian; Kerr, Keith M; Naidu, Babu; Middleton, Gary; Summers, Yvonne; Lindsay, Colin R; Blackhall, Fiona H; Cave, Judith; Blyth, Kevin G; Nair, Arjun; Ahmed, Asia; Taylor, Magali N; Procter, Alexander James; Falzon, Mary; Lawrence, David; Navani, Neal; Thakrar, Ricky M; Janes, Sam M; Papadatos-Pastos, Dionysis; Forster, Martin D; Lee, Siow Ming; Ahmad, Tanya; Quezada, Sergio A; Peggs, Karl S; Van Loo, Peter; Dive, Caroline; Hackshaw, Allan; Birkbak, Nicolai J; Zaccaria, Simone; TRACERx Consortium, .; Jamal-Hanjani, Mariam; McGranahan, Nicholas; Swanton, Charles; - view fewer (2023) The evolution of non-small cell lung cancer metastases in TRACERx. Nature 10.1038/s41586-023-05729-x. (In press).

Alwan, NA; Burgess, RA; Ashworth, S; Beale, R; Bhadelia, N; Bogaert, D; Dowd, J; ... Ziauddeen, H; + view all Alwan, NA; Burgess, RA; Ashworth, S; Beale, R; Bhadelia, N; Bogaert, D; Dowd, J; Eckerle, I; Goldman, LR; Greenhalgh, T; Gurdasani, D; Hamdy, A; Hanage, WP; Hodcroft, EB; Hyde, Z; Kellam, P; Kelly-Irving, M; Krammer, F; Lipsitch, M; McNally, A; McKee, M; Nouri, A; Pimenta, D; Priesemann, V; Rutter, H; Silver, J; Sridhar, D; Swanton, C; Walensky, RP; Yamey, G; Ziauddeen, H; - view fewer (2020) Scientific consensus on the COVID-19 pandemic: we need to act now. The Lancet , 396 (10260) e71-e72. 10.1016/S0140-6736(20)32153-X.

Au, L; Fendler, A; Shepherd, STC; Rzeniewicz, K; Cerrone, M; Byrne, F; Carlyle, E; ... Turajlic, S; + view all Au, L; Fendler, A; Shepherd, STC; Rzeniewicz, K; Cerrone, M; Byrne, F; Carlyle, E; Edmonds, K; Del Rosario, L; Shon, J; Haynes, WA; Ward, B; Shum, B; Gordon, W; Gerard, CL; Xie, W; Joharatnam-Hogan, N; Young, K; Pickering, L; Furness, AJS; Larkin, J; Harvey, R; Kassiotis, G; Gandhi, S; Swanton, C; Fribbens, C; Wilkinson, KA; Wilkinson, RJ; Lau, DK; Banerjee, S; Starling, N; Chau, I; Turajlic, S; - view fewer (2021) Cytokine release syndrome in a patient with colorectal cancer after vaccination with BNT162b2. Nature Medicine 10.1038/s41591-021-01387-6.

Bailey, C; Black, JRM; Reading, JL; Litchfield, K; Turajlic, S; McGranahan, N; Jamal-Hanjani, M; Bailey, C; Black, JRM; Reading, JL; Litchfield, K; Turajlic, S; McGranahan, N; Jamal-Hanjani, M; Swanton, C; - view fewer (2021) Tracking Cancer Evolution through the Disease Course. Cancer Discovery , 11 (4) pp. 916-932. 10.1158/2159-8290.CD-20-1559.

Bailey, Chris; Pich, Oriol; Thol, Kerstin; Watkins, Thomas BK; Luebeck, Jens; Rowan, Andrew; Stavrou, Georgia; ... Swanton, Charles; + view all Bailey, Chris; Pich, Oriol; Thol, Kerstin; Watkins, Thomas BK; Luebeck, Jens; Rowan, Andrew; Stavrou, Georgia; Weiser, Natasha E; Dameracharla, Bhargavi; Bentham, Robert; Lu, Wei-Ting; Kittel, Jeanette; Yang, SY Cindy; Howitt, Brooke E; Sharma, Natasha; Litovchenko, Maria; Salgado, Roberto; Hung, King L; Cornish, Alex J; Moore, David A; Houlston, Richard S; Bafna, Vineet; Chang, Howard Y; Nik-Zainal, Serena; Kanu, Nnennaya; McGranahan, Nicholas; Flanagan, Adrienne M; Mischel, Paul S; Jamal-Hanjani, Mariam; Swanton, Charles; - view fewer (2024) Origins and impact of extrachromosomal DNA. Nature , 635 (8037) pp. 193-200. 10.1038/s41586-024-08107-3.

Bailey, C; Black, JRM; Swanton, C; (2020) Cancer Research: The Lessons to Learn from COVID-19. Cancer Discovery , 10 (9) pp. 1263-1266. 10.1158/2159-8290.CD-20-0823.

Bailey, C; Shoura, MJ; Mischel, PS; Swanton, C; (2020) Extrachromosomal DNA d relieving heredity constraints, accelerating tumour evolution. Annals of Oncology , 31 (7) pp. 884-893. 10.1016/j.annonc.2020.03.303.

Bakhoum, SF; Ngo, B; Laughney, AM; Cavallo, J-A; Murphy, CJ; Ly, P; Shah, P; ... Cantley, LC; + view all Bakhoum, SF; Ngo, B; Laughney, AM; Cavallo, J-A; Murphy, CJ; Ly, P; Shah, P; Sriram, RK; Watkins, TBK; Taunk, NK; Duran, M; Pauli, C; Shaw, C; Chadalavada, K; Rajasekhar, VK; Genovese, G; Venkatesan, S; Birkbak, NJ; McGranahan, N; Lundquist, M; LaPlant, Q; Healey, JH; Elemento, O; Chung, CH; Lee, NY; Imielenski, M; Nanjangud, G; Pe'er, D; Cleveland, DW; Powell, SN; Lammerding, J; Swanton, C; Cantley, LC; - view fewer (2018) Chromosomal instability drives metastasis through a cytosolic DNA response. Nature , 553 (7689) pp. 467-472. 10.1038/nature25432.

Balestrini, S; Koepp, MJ; Gandhi, S; Rickman, HM; Yen Shin, G; Houlihan, CF; Anders-Cannon, J; ... Sisodiya, SM; + view all Balestrini, S; Koepp, MJ; Gandhi, S; Rickman, HM; Yen Shin, G; Houlihan, CF; Anders-Cannon, J; Silvennoinen, K; Xiao, F; Zagaglia, S; Hudgell, K; Ziomek, M; Haimes, P; Sampson, A; Parker, A; Helen Cross, J; Pardington, R; Nastouli, E; Swanton, C; Sander, JW; Sisodiya, SM; - view fewer (2021) Clinical outcomes of COVID-19 in long-term care facilities for people with epilepsy. Epilepsy & Behavior , 115 , Article 107602. 10.1016/j.yebeh.2020.107602.

Barbieri, CE; Chinnaiyan, AM; Lerner, SP; Swanton, C; Rubin, MA; (2017) The Emergence of Precision Urologic Oncology: A Collaborative Review on Biomarker-driven Therapeutics. European Urology , 71 (2) pp. 237-246. 10.1016/j.eururo.2016.08.024.

Barrett, JE; Feber, A; Herrero, J; Tanic, M; Wilson, GA; Swanton, C; Beck, S; (2017) Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection. BMC Bioinformatics , 18 , Article 354. 10.1186/s12859-017-1753-2.

Bentham, R; Litchfield, K; Watkins, TBK; Lim, EL; Rosenthal, R; Martinez-Ruiz, C; Hiley, CT; ... McGranahan, N; + view all Bentham, R; Litchfield, K; Watkins, TBK; Lim, EL; Rosenthal, R; Martinez-Ruiz, C; Hiley, CT; Al Bakir, M; Salgado, R; Moore, DA; Jamal-Hanjani, M; Swanton, C; McGranahan, N; - view fewer (2021) Using DNA sequencing data to quantify T cell fraction and therapy response. Nature , 597 pp. 555-560. 10.1038/s41586-021-03894-5.

Bentzen, AK; Marquard, AM; Lyngaa, R; Saini, SK; Ramskov, S; Donia, M; Such, L; ... Hadrup, SR; + view all Bentzen, AK; Marquard, AM; Lyngaa, R; Saini, SK; Ramskov, S; Donia, M; Such, L; Furness, AJS; McGranahan, N; Rosenthal, R; Straten, PT; Szallasi, Z; Svane, IM; Swanton, C; Quezada, SA; Jakobsen, SN; Eklund, AC; Hadrup, SR; - view fewer (2016) Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes. Nature Biotechnology , 34 (10) pp. 1037-1045. 10.1038/nbt.3662.

Berenjeno, IM; Piñeiro, R; Castillo, SD; Pearce, W; McGranahan, N; Dewhurst, SM; Meniel, V; ... Vanhaesebroeck, B; + view all Berenjeno, IM; Piñeiro, R; Castillo, SD; Pearce, W; McGranahan, N; Dewhurst, SM; Meniel, V; Birkbak, NJ; Lau, E; Sansregret, L; Morelli, D; Kanu, N; Srinivas, S; Graupera, M; Parker, VER; Montgomery, KG; Moniz, LS; Scudamore, CL; Phillips, WA; Semple, RK; Clarke, A; Swanton, C; Vanhaesebroeck, B; - view fewer (2017) Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling. Nature Communications , 8 , Article 1773. 10.1038/s41467-017-02002-4.

Bi, WL; Hosny, A; Schabath, MB; Giger, ML; Birkbak, NJ; Mehrtash, A; Allison, T; ... Aerts, HJWL; + view all Bi, WL; Hosny, A; Schabath, MB; Giger, ML; Birkbak, NJ; Mehrtash, A; Allison, T; Arnaout, O; Abbosh, C; Dunn, IF; Mak, RH; Tamimi, RM; Tempany, CM; Swanton, C; Hoffmann, U; Schwartz, LH; Gillies, RJ; Huang, RY; Aerts, HJWL; - view fewer (2019) Artificial intelligence in cancer imaging: Clinical challenges and applications. CA: A Cancer Journal for Clinicians , 69 (2) pp. 127-157. 10.3322/caac.21552.

Biswas, Dhruva; Liu, Yun-Hsin; Herrero, Javier; Wu, Yin; Moore, David A; Karasaki, Takahiro; Grigoriadis, Kristiana; ... Swanton, Charles; + view all Biswas, Dhruva; Liu, Yun-Hsin; Herrero, Javier; Wu, Yin; Moore, David A; Karasaki, Takahiro; Grigoriadis, Kristiana; Lu, Wei-Ting; Veeriah, Selvaraju; Naceur-Lombardelli, Cristina; Magno, Neil; Ward, Sophia; Frankell, Alexander M; Hill, Mark S; Colliver, Emma; De Carné Trécesson, Sophie; East, Philip; Malhi, Aman; Snell, Daniel M; O'Neill, Olga; Leonce, Daniel; Mattsson, Johanna; Lindberg, Amanda; Micke, Patrick; Moldvay, Judit; Megyesfalvi, Zsolt; Dome, Balasz; Fillinger, János; Nicod, Jerome; Downward, Julian; Szallasi, Zoltan; TRACERx Consortium; Hackshaw, Allan; Jamal-Hanjani, Mariam; Kanu, Nnennaya; Birkbak, Nicolai J; Swanton, Charles; - view fewer (2025) Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma adenocarcinoma. Nature Cancer , 6 pp. 86-101. 10.1038/s43018-024-00883-1.

Biswas, D; Birkbak, NJ; Rosenthal, R; Hiley, CT; Lim, EL; Papp, K; Boeing, S; ... TRACERx Consortium; + view all Biswas, D; Birkbak, NJ; Rosenthal, R; Hiley, CT; Lim, EL; Papp, K; Boeing, S; Krzystanek, M; Djureinovic, D; La Fleur, L; Greco, M; Döme, B; Fillinger, J; Brunnström, H; Wu, Y; Moore, DA; Skrzypski, M; Abbosh, C; Litchfield, K; Al Bakir, M; Watkins, TBK; Veeriah, S; Wilson, GA; Jamal-Hanjani, M; Moldvay, J; Botling, J; Chinnaiyan, AM; Micke, P; Hackshaw, A; Bartek, J; Csabai, I; Szallasi, Z; Herrero, J; McGranahan, N; Swanton, C; TRACERx Consortium; - view fewer (2019) A clonal expression biomarker associates with lung cancer mortality. Nature Medicine , 25 pp. 1540-1548. 10.1038/s41591-019-0595-z.

Black, James RM; Bartha, Gabor; Abbott, Charles W; Boyle, Sean M; Karasaki, Takahiro; Li, Bailiang; Chen, Rui; ... Swanton, Charles; + view all Black, James RM; Bartha, Gabor; Abbott, Charles W; Boyle, Sean M; Karasaki, Takahiro; Li, Bailiang; Chen, Rui; Harris, Jason; Veeriah, Selvaraju; Colopi, Martina; Al Bakir, Maise; Liu, Wing Kin; Lyle, John; Navarro, Fabio CP; Northcott, Josette; Pyke, Rachel Marty; Hill, Mark S; Thol, Kerstin; Huebner, Ariana; Bailey, Chris; Colliver, Emma C; Martinez-Ruiz, Carlos; Grigoriadis, Kristiana; Pawlik, Piotr; Moore, David A; Marinelli, Daniele; Shutkever, Oliver G; Murphy, Cian; Sivakumar, Monica; Shaw, Jacqui A; Hackshaw, Allan; McGranahan, Nicholas; Jamal-Hanjani, Mariam; Frankell, Alexander M; Chen, Richard O; Swanton, Charles; - view fewer (2025) Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma. Nature Medicine , 31 pp. 70-76. 10.1038/s41591-024-03216-y.

Black, JRM; Bailey, C; Przewrocka, J; Dijkstra, KK; Swanton, C; (2020) COVID-19: the case for health-care worker screening to prevent hospital transmission. The Lancet , 395 (10234) pp. 1418-1420. 10.1016/S0140-6736(20)30917-X.

Blagih, J; Zani, F; Chakravarty, P; Hennequart, M; Pilley, S; Hobor, S; Hock, AK; ... Vousden, KH; + view all Blagih, J; Zani, F; Chakravarty, P; Hennequart, M; Pilley, S; Hobor, S; Hock, AK; Walton, JB; Morton, JP; Gronroos, E; Mason, S; Yang, M; McNeish, I; Swanton, C; Blyth, K; Vousden, KH; - view fewer (2020) Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses. Cell Reports , 30 (2) 481-496.e6. 10.1016/j.celrep.2019.12.028.

Blakely, CM; Watkins, TBK; Wu, W; Gini, B; Chabon, JJ; McCoach, CE; McGranahan, N; ... Bivona, TG; + view all Blakely, CM; Watkins, TBK; Wu, W; Gini, B; Chabon, JJ; McCoach, CE; McGranahan, N; Wilson, GA; Birkbak, NJ; Olivas, VR; Rotow, J; Maynard, A; Wang, V; Gubens, MA; Banks, KC; Lanman, RB; Caulin, AF; St John, J; Cordero, AR; Giannikopoulos, P; Simmons, AD; Mack, PC; Gandara, DR; Husain, H; Doebele, RC; Riess, JW; Diehn, M; Swanton, C; Bivona, TG; - view fewer (2017) Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers. Nature Genetics , 49 (12) pp. 1693-1704. 10.1038/ng.3990.

Boire, Adrienne; Burke, Katy; Cox, Thomas R; Guise, Theresa; Jamal-Hanjani, Mariam; Janowitz, Tobias; Kaplan, Rosandra; ... Sahai, Erik; + view all Boire, Adrienne; Burke, Katy; Cox, Thomas R; Guise, Theresa; Jamal-Hanjani, Mariam; Janowitz, Tobias; Kaplan, Rosandra; Lee, Rebecca; Swanton, Charles; Vander Heiden, Matthew G; Sahai, Erik; - view fewer (2024) Why do patients with cancer die? Nature Reviews Cancer , 24 (8) pp. 578-589. 10.1038/s41568-024-00708-4.

Bortolomeazzi, M; Keddar, MR; Montorsi, L; Acha-Sagredo, A; Benedetti, L; Temelkovski, D; Choi, S; ... Ciccarelli, FD; + view all Bortolomeazzi, M; Keddar, MR; Montorsi, L; Acha-Sagredo, A; Benedetti, L; Temelkovski, D; Choi, S; Petrov, N; Todd, K; Wai, P; Kohl, J; Denner, T; Nye, E; Goldstone, R; Ward, S; Wilson, GA; Al Bakir, M; Swanton, C; John, S; Miles, J; Larijani, B; Kunene, V; Fontana, E; Arkenau, H-T; Parker, PJ; Rodriguez-Justo, M; Shiu, K-K; Spencer, J; Ciccarelli, FD; - view fewer (2021) Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts. Gastroenterology 10.1053/j.gastro.2021.06.064. (In press).

Boumelha, Jesse; de Carné Trécesson, Sophie; Law, Emily K; Romero-Clavijo, Pablo; Coelho, Matthew; Ng, Kevin; Mugarza, Edurne; ... Downward, Julian; + view all Boumelha, Jesse; de Carné Trécesson, Sophie; Law, Emily K; Romero-Clavijo, Pablo; Coelho, Matthew; Ng, Kevin; Mugarza, Edurne; Moore, Christopher; Rana, Sareena; Caswell, Deborah R; Murillo, Miguel; Hancock, David C; Argyris, Prokopios P; Brown, William L; Durfee, Cameron; Larson, Lindsay K; Vogel, Rachel I; Suarez-Bonnet, Alejandro; Priestnall, Simon L; East, Philip; Ross, Sarah J; Kassiotis, George; Molina-Arcas, Miriam; Swanton, Charles; Harris, Reuben; Downward, Julian; - view fewer (2022) An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations. Cancer Research , 82 (19) pp. 3435-3448. 10.1158/0008-5472.CAN-22-0325.

Buck, M; Poirier, E; Cardoso, A; Frederico, B; Canton, J; Barrell, S; Beale, R; ... The Crick COVID-19 Consortium; + view all Buck, M; Poirier, E; Cardoso, A; Frederico, B; Canton, J; Barrell, S; Beale, R; Byrne, R; Caidan, S; Crawford, M; Cubitt, L; Gandhi, S; Goldstone, R; Grant, P; Gulati, K; Hindmarsh, S; Howell, M; Hubank, M; Instrell, R; Jiang, M; Kassiotis, G; Lu, W-T; MacRae, J; Martini, I; Miller, D; Moore, D; Nastouli, E; Nicod, J; Nightingale, L; Olsen, J; Oomatia, A; O'Reilly, N; Rideg, A; Song, O-R; Strange, A; Swanton, C; Turajlic, S; Wu, M; Reis e Sousa, C; The Crick COVID-19 Consortium; - view fewer (2021) SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay [version 1; peer review: 1 approved with reservations]. Wellcome Open Research , 6 (9) 10.12688/wellcomeopenres.16517.1.

Buck, MD; Poirier, EZ; Cardoso, A; Frederico, B; Canton, J; Barrell, S; Beale, R; ... Crick COVID-19 Consortium; + view all Buck, MD; Poirier, EZ; Cardoso, A; Frederico, B; Canton, J; Barrell, S; Beale, R; Byrne, R; Caidan, S; Crawford, M; Cubitt, L; Gandhi, S; Goldstone, R; Grant, PR; Gulati, K; Hindmarsh, S; Howell, M; Hubank, M; Instrell, R; Jiang, M; Kassiotis, G; Lu, W-T; MacRae, JI; Martini, I; Miller, D; Moore, D; Nastouli, E; Nicod, J; Nightingale, L; Olsen, J; Oomatia, A; O'Reilly, N; Rideg, A; Song, O-R; Strange, A; Swanton, C; Turajlic, S; Wu, M; Reis E Sousa, C; Crick COVID-19 Consortium; - view fewer (2021) SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay. Wellcome Open Research , 6 , Article 9. 10.12688/wellcomeopenres.16517.2.

Budczies, J; Allgäuer, M; Litchfield, K; Rempel, E; Christopoulos, P; Kazdal, D; Endris, V; ... Stenzinger, A; + view all Budczies, J; Allgäuer, M; Litchfield, K; Rempel, E; Christopoulos, P; Kazdal, D; Endris, V; Thomas, M; Fröhling, S; Peters, S; Swanton, C; Schirmacher, P; Stenzinger, A; - view fewer (2019) Optimizing panel-based tumor mutational burden (TMB) measurement. Annals of Oncology , 30 (9) pp. 1496-1506. 10.1093/annonc/mdz205.

Burrell, Rebecca A; McClelland, Sarah E; Endesfelder, David; Groth, Petra; Weller, Marie-Christine; Shaikh, Nadeem; Domingo, Enric; ... Swanton, Charles; + view all Burrell, Rebecca A; McClelland, Sarah E; Endesfelder, David; Groth, Petra; Weller, Marie-Christine; Shaikh, Nadeem; Domingo, Enric; Kanu, Nnennaya; Dewhurst, Sally M; Gronroos, Eva; Chew, Su Kit; Rowan, Andrew J; Schenk, Arne; Sheffer, Michal; Howell, Michael; Kschischo, Maik; Behrens, Axel; Helleday, Thomas; Bartek, Jiri; Tomlinson, Ian R; Swanton, Charles; - view fewer (2013) Replication stress links structural and numerical cancer chromosomal instability. Nature , 494 (7438) pp. 492-496. 10.1038/nature11935.

Cai, H; Chew, SK; Li, C; Tsai, MK; Andrejka, L; Murray, CW; Hughes, NW; ... Winslow, MM; + view all Cai, H; Chew, SK; Li, C; Tsai, MK; Andrejka, L; Murray, CW; Hughes, NW; Shuldiner, EG; Ashkin, EL; Tang, R; Hung, KL; Chen, LC; Lee, SYC; Yousefi, M; Lin, W-Y; Kunder, CA; Cong, L; McFarland, CD; Petrov, DA; Swanton, C; Winslow, MM; - view fewer (2021) A Functional Taxonomy of Tumor Suppression in Oncogenic KRAS-Driven Lung Cancer. Cancer Discovery , 11 (7) pp. 1754-1773. 10.1158/2159-8290.CD-20-1325.

Caswell, Deborah R; Gui, Philippe; Mayekar, Manasi K; Law, Emily K; Pich, Oriol; Bailey, Chris; Boumelha, Jesse; ... Swanton, Charles; + view all Caswell, Deborah R; Gui, Philippe; Mayekar, Manasi K; Law, Emily K; Pich, Oriol; Bailey, Chris; Boumelha, Jesse; Kerr, D Lucas; Blakely, Collin M; Manabe, Tadashi; Martinez-Ruiz, Carlos; Bakker, Bjorn; De Dios Palomino Villcas, Juan; I Vokes, Natalie; Dietzen, Michelle; Angelova, Mihaela; Gini, Beatrice; Tamaki, Whitney; Allegakoen, Paul; Wu, Wei; Humpton, Timothy J; Hill, William; Tomaschko, Mona; Lu, Wei-Ting; Haderk, Franziska; Al Bakir, Maise; Nagano, Ai; Gimeno-Valiente, Francisco; de Carné Trécesson, Sophie; Vendramin, Roberto; Barbè, Vittorio; Mugabo, Miriam; Weeden, Clare E; Rowan, Andrew; McCoach, Caroline E; Almeida, Bruna; Green, Mary; Gomez, Carlos; Nanjo, Shigeki; Barbosa, Dora; Moore, Chris; Przewrocka, Joanna; Black, James RM; Grönroos, Eva; Suarez-Bonnet, Alejandro; Priestnall, Simon L; Zverev, Caroline; Lighterness, Scott; Cormack, James; Olivas, Victor; Cech, Lauren; Andrews, Trisha; Rule, Brandon; Jiao, Yuwei; Zhang, Xinzhu; Ashford, Paul; Durfee, Cameron; Venkatesan, Subramanian; Temiz, Nuri Alpay; Tan, Lisa; Larson, Lindsay K; Argyris, Prokopios P; Brown, William L; Yu, Elizabeth A; Rotow, Julia K; Guha, Udayan; Roper, Nitin; Yu, Johnny; Vogel, Rachel I; Thomas, Nicholas J; Marra, Antonio; Selenica, Pier; Yu, Helena; Bakhoum, Samuel F; Chew, Su Kit; Reis-Filho, Jorge S; Jamal-Hanjani, Mariam; Vousden, Karen H; McGranahan, Nicholas; Van Allen, Eliezer M; Kanu, Nnennaya; Harris, Reuben S; Downward, Julian; Bivona, Trever G; Swanton, Charles; - view fewer (2023) The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance. Nature Genetics 10.1038/s41588-023-01592-8. (In press).

Caswell, DR; Swanton, C; (2017) The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome. [Review]. BMC Medicine , 15 , Article 133. 10.1186/s12916-017-0900-y.

Cerone, Maria Antonietta; Mills, Tara C; Sharpe, Rowena; McBride, David; MacDonald, Moira; MacMahon, Suzanne; Mugalaasi, Hood; ... SMP2, consortium; + view all Cerone, Maria Antonietta; Mills, Tara C; Sharpe, Rowena; McBride, David; MacDonald, Moira; MacMahon, Suzanne; Mugalaasi, Hood; Rehal, Pauline; Rettino, Alessandro; Roberts, Helen; Ross, Mark; White, Donald Edward; Peden, John; Rawlings, Janette; Ho, Stephan N; Hollingsworth, Simon; Popat, Sanjay; Middleton, Gary; Johnson, Peter; Swanton, Charles; SMP2, consortium; - view fewer (2023) The Cancer Research UK Stratified Medicine Programme as a model for delivering personalised cancer care. British Journal of Cancer 10.1038/s41416-022-02107-8. (In press).

Chafe, Shawn C; Zhai, Kui; Aghaei, Nikoo; Miletic, Petar; Huang, Zhi; Brown, Kevin R; Mobilio, Daniel; ... Singh, Sheila K; + view all Chafe, Shawn C; Zhai, Kui; Aghaei, Nikoo; Miletic, Petar; Huang, Zhi; Brown, Kevin R; Mobilio, Daniel; Young, Daniel; Suk, Yujin; Grewal, Shan; McKenna, Dillon; Alizada, Zahra; Kieliszek, Agata M; Lam, Fred C; Escudero, Laura; Huang, Qian; Huebner, Ariana; Lu, Jack; Ang, Patrick; Anand, Alisha; Custers, Stefan; Apel, Erika; Slassi, Sarah; Brakel, Benjamin; Kim, Jongmyung; Liu, James KC; Bassey-Archibong, Blessing Iquo; Abdo, Rober; Shargall, Yaron; Lu, Jian-Qiang; Cutz, Jean-Claude; Zhang, Qi; Li, Shawn Shun-Cheng; Venugopal, Chitra; Hynds, Robert E; Dufour, Antoine; Moffat, Jason; Swanton, Charles; Bao, Shideng; Singh, Sheila K; - view fewer (2025) A genome-wide in vivo CRISPR activation screen identifies BACE1 as a therapeutic vulnerability of lung cancer brain metastasis. Science Translational Medicine , 17 (805) 10.1126/scitranslmed.adu2459.

Chan, TA; Yarchoan, M; Jaffee, E; Swanton, C; Quezada, SA; Stenzinger, A; Peters, S; (2019) Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic. Annals of Oncology , 30 (1) pp. 44-56. 10.1093/annonc/mdy495.

Chemi, F; Rothwell, DG; McGranahan, N; Gulati, S; Abbosh, C; Pearce, SP; Zhou, C; ... TRACERx Consortium, .; + view all Chemi, F; Rothwell, DG; McGranahan, N; Gulati, S; Abbosh, C; Pearce, SP; Zhou, C; Wilson, GA; Jamal-Hanjani, M; Birkbak, N; Pierce, J; Kim, CS; Ferdous, S; Burt, DJ; Slane-Tan, D; Gomes, F; Moore, D; Shah, R; Al Bakir, M; Hiley, C; Veeriah, S; Summers, Y; Crosbie, P; Ward, S; Mesquita, B; Dynowski, M; Biswas, D; Tugwood, J; Blackhall, F; Miller, C; Hackshaw, A; Brady, G; Swanton, C; Dive, C; TRACERx Consortium, .; - view fewer (2019) Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse. Nature Medicine , 25 pp. 1534-1539. 10.1038/s41591-019-0593-1.

Chu, Yanshuo; Dai, Enyu; Li, Yating; Han, Guangchun; Pei, Guangsheng; Ingram, Davis R; Thakkar, Krupa; ... Wang, Linghua; + view all Chu, Yanshuo; Dai, Enyu; Li, Yating; Han, Guangchun; Pei, Guangsheng; Ingram, Davis R; Thakkar, Krupa; Qin, Jiang-Jiang; Dang, Minghao; Le, Xiuning; Hu, Can; Deng, Qing; Sinjab, Ansam; Gupta, Pravesh; Wang, Ruiping; Hao, Dapeng; Peng, Fuduan; Yan, Xinmiao; Liu, Yunhe; Song, Shumei; Zhang, Shaojun; Heymach, John V; Reuben, Alexandre; Elamin, Yasir Y; Pizzi, Melissa P; Lu, Yang; Lazcano, Rossana; Hu, Jian; Li, Mingyao; Curran, Michael; Futreal, Andrew; Maitra, Anirban; Jazaeri, Amir A; Ajani, Jaffer A; Swanton, Charles; Cheng, Xiang-Dong; Abbas, Hussein A; Gillison, Maura; Bhat, Krishna; Lazar, Alexander J; Green, Michael; Litchfield, Kevin; Kadara, Humam; Yee, Cassian; Wang, Linghua; - view fewer (2023) Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance. Nature Medicine , 29 (6) pp. 1550-1562. 10.1038/s41591-023-02371-y.

Conforti, F; Pala, L; Pagan, E; Bagnardi, V; De Pas, T; Queirolo, P; Pennacchioli, E; ... Giaccone, G; + view all Conforti, F; Pala, L; Pagan, E; Bagnardi, V; De Pas, T; Queirolo, P; Pennacchioli, E; Catania, C; Cocorocchio, E; Ferrucci, PF; Saponara, M; Orsolini, G; Zagami, P; Nicoló, E; De Marinis, F; Tortora, G; Bria, E; Minucci, S; Joffe, H; Veronesi, P; Wargo, J; Rosenthal, R; Swanton, C; Mantovani, A; Gelber, RD; Viale, G; Goldhirsch, A; Giaccone, G; - view fewer (2021) Sex-Based Dimorphism of Anticancer Immune Response and Molecular Mechanisms of Immune Evasion. Clinical Cancer Research , 27 (15) pp. 4311-4324. 10.1158/1078-0432.CCR-21-0136.

Crockford, A; Zalmas, LP; Grönroos, E; Dewhurst, SM; McGranahan, N; Cuomo, ME; Encheva, V; ... Swanton, C; + view all Crockford, A; Zalmas, LP; Grönroos, E; Dewhurst, SM; McGranahan, N; Cuomo, ME; Encheva, V; Snijders, AP; Begum, J; Purewal, S; Cerveira, J; Patel, H; Renshaw, MJ; Swanton, C; - view fewer (2017) Cyclin D mediates tolerance of genome-doubling in cancers with functional p53. Annals of Oncology , 28 (1) pp. 149-156. 10.1093/annonc/mdw612.

DeGregori, James; Pharoah, Paul; Sasieni, Peter; Swanton, Charles; (2020) Cancer Screening, Surrogates of Survival, and the Soma. Cancer Cell , 38 (4) pp. 433-437. 10.1016/j.ccell.2020.09.003.

Dentro, SC; Leshchiner, I; Haase, K; Tarabichi, M; Wintersinger, J; Deshwar, AG; Yu, K; ... PCAWG Evolution and Heterogeneity Working Group and the PCAWG Co, .; + view all Dentro, SC; Leshchiner, I; Haase, K; Tarabichi, M; Wintersinger, J; Deshwar, AG; Yu, K; Rubanova, Y; Macintyre, G; Demeulemeester, J; Vázquez-García, I; Kleinheinz, K; Livitz, DG; Malikic, S; Donmez, N; Sengupta, S; Anur, P; Jolly, C; Cmero, M; Rosebrock, D; Schumacher, SE; Fan, Y; Fittall, M; Drews, RM; Yao, X; Watkins, TBK; Lee, J; Schlesner, M; Zhu, H; Adams, DJ; McGranahan, N; Swanton, C; Getz, G; Boutros, PC; Imielinski, M; Beroukhim, R; Sahinalp, SC; Ji, Y; Peifer, M; Martincorena, I; Markowetz, F; Mustonen, V; Yuan, K; Gerstung, M; Spellman, PT; Wang, W; Morris, QD; Wedge, DC; Van Loo, P; PCAWG Evolution and Heterogeneity Working Group and the PCAWG Co, .; - view fewer (2021) Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes. Cell , 184 (8) pp. 2239-2254. 10.1016/j.cell.2021.03.009.

Dietzen, Michelle; Zhai, Haoran; Lucas, Olivia; Pich, Oriol; Barrington, Christopher; Lu, Wei-Ting; Ward, Sophia; ... Kanu, Nnennaya; + view all Dietzen, Michelle; Zhai, Haoran; Lucas, Olivia; Pich, Oriol; Barrington, Christopher; Lu, Wei-Ting; Ward, Sophia; Guo, Yanping; Hynds, Robert E; Zaccaria, Simone; Swanton, Charles; McGranahan, Nicholas; Kanu, Nnennaya; - view fewer (2024) Replication timing alterations are associated with mutation acquisition during breast and lung cancer evolution. Nature Communications , 15 (1) , Article 6039. 10.1038/s41467-024-50107-4.

Domingues, PH; Nanduri, LSY; Seget, K; Venkateswaran, SV; Agorku, D; Vigano, C; von Schubert, C; ... Hardt, O; + view all Domingues, PH; Nanduri, LSY; Seget, K; Venkateswaran, SV; Agorku, D; Vigano, C; von Schubert, C; Nigg, EA; Swanton, C; Sotillo, R; Bosio, A; Storchova, Z; Hardt, O; - view fewer (2017) Cellular Prion Protein PrPC and Ecto-5′-Nucleotidase Are Markers of the Cellular Stress Response to Aneuploidy. Cancer Research , 77 (11) pp. 2914-2926. 10.1158/0008-5472.CAN-16-3052.

Dowgier, G; Hobbs, A; Greenwood, D; Shawe-Taylor, M; Stevenson-Leggett, P; Bazire, J; Penn, R; ... Wu, MY; + view all Dowgier, G; Hobbs, A; Greenwood, D; Shawe-Taylor, M; Stevenson-Leggett, P; Bazire, J; Penn, R; Harvey, R; Libri, V; Kassiotis, G; Gamblin, S; Lewis, NS; Williams, B; Swanton, C; Gandhi, S; Bauer, DLV; Carr, EJ; Wall, EC; Wu, MY; - view fewer (2025) Accurate evaluation of live-virus microneutralisation for SARS-CoV-2 variant JN.1 in the assessment of vaccination and therapeutics. Vaccine , 54 , Article 126960. 10.1016/j.vaccine.2025.126960.

Endesfelder, David; Burrell, Rebecca A; Kanu, Nnennaya; McGranahan, Nicholas; Howell, Mike; Parker, Peter J; Downward, Julian; ... Kschischo, Maik; + view all Endesfelder, David; Burrell, Rebecca A; Kanu, Nnennaya; McGranahan, Nicholas; Howell, Mike; Parker, Peter J; Downward, Julian; Swanton, Charles; Kschischo, Maik; - view fewer (2014) Chromosomal instability selects gene copy number variants encoding core regulators of proliferation in ER+ breast cancer. Cancer Research , 74 (17) pp. 4853-4863. 10.1158/0008-5472.CAN-13-2664.

Enfield, Katey SS; Colliver, Emma; Lee, Claudia SY; Magness, Alastair; Moore, David A; Sivakumar, Monica; Grigoriadis, Kristiana; ... Angelova, Mihaela; + view all Enfield, Katey SS; Colliver, Emma; Lee, Claudia SY; Magness, Alastair; Moore, David A; Sivakumar, Monica; Grigoriadis, Kristiana; Pich, Oriol; Karasaki, Takahiro; Hobson, Philip S; Levi, Dina; Veeriah, Selvaraju; Puttick, Clare; Nye, Emma L; Green, Mary; Dijkstra, Krijn K; Shimato, Masako; Akarca, Ayse U; Marafioti, Teresa; Salgado, Roberto; Hackshaw, Allan; Consortium, TRACERx; Jamal-Hanjani, Mariam; van Maldegem, Febe; McGranahan, Nicholas; Glass, Benjamin; Pulaski, Hanna; Walk, Eric; Reading, James L; Quezada, Sergio A; Hiley, Crispin T; Downward, Julian; Sahai, Erik; Swanton, Charles; Angelova, Mihaela; - view fewer (2024) Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer. Cancer Discovery , 14 (1) pp. 1-30. 10.1158/2159-8290.CD-23-1380.

Fendler, A; Au, L; Shepherd, STC; Byrne, F; Cerrone, M; Boos, LA; Rzeniewicz, K; ... Wilkinson, RJ; + view all Fendler, A; Au, L; Shepherd, STC; Byrne, F; Cerrone, M; Boos, LA; Rzeniewicz, K; Gordon, W; Shum, B; Gerard, CL; Ward, B; Xie, W; Schmitt, AM; Joharatnam-Hogan, N; Cornish, GH; Pule, M; Mekkaoui, L; Ng, KW; Carlyle, E; Edmonds, K; Rosario, LD; Sarker, S; Lingard, K; Mangwende, M; Holt, L; Ahmod, H; Stone, R; Gomes, C; Flynn, HR; Agua-Doce, A; Hobson, P; Caidan, S; Howell, M; Wu, M; Goldstone, R; Crawford, M; Cubitt, L; Patel, H; Gavrielides, M; Nye, E; Snijders, AP; MacRae, JI; Nicod, J; Gronthoud, F; Shea, RL; Messiou, C; Cunningham, D; Chau, I; Starling, N; Turner, N; Welsh, L; van As, N; Jones, RL; Droney, J; Banerjee, S; Tatham, KC; Jhanji, S; O’Brien, M; Curtis, O; Harrington, K; Bhide, S; Bazin, J; Robinson, A; Stephenson, C; Slattery, T; Khan, Y; Tippu, Z; Leslie, I; Gennatas, S; Okines, A; Reid, A; Young, K; Furness, AJS; Pickering, L; Gandhi, S; Gamblin, S; Swanton, C; Flynn, HR; Howell, M; Wu, M; Goldstone, R; Crawford, M; Nicod, J; Nicholson, E; Kumar, S; Yousaf, N; Wilkinson, KA; Swerdlow, A; Harvey, R; Kassiotis, G; Larkin, J; Wilkinson, RJ; Turajlic, S; Wilkinson, KA; Swerdlow, A; Wilkinson, RJ; - view fewer (2021) Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study. Nature Cancer 10.1038/s43018-021-00275-9. (In press).

Fendler, A; Shepherd, STC; Au, L; Wilkinson, KA; Wu, M; Byrne, F; Cerrone, M; ... Turajlic, S; + view all Fendler, A; Shepherd, STC; Au, L; Wilkinson, KA; Wu, M; Byrne, F; Cerrone, M; Schmitt, AM; Joharatnam-Hogan, N; Shum, B; Tippu, Z; Rzeniewicz, K; Boos, LA; Harvey, R; Carlyle, E; Edmonds, K; Del Rosario, L; Sarker, S; Lingard, K; Mangwende, M; Holt, L; Ahmod, H; Korteweg, J; Foley, T; Bazin, J; Gordon, W; Barber, T; Emslie-Henry, A; Xie, W; Gerard, CL; Deng, D; Wall, EC; Agua-Doce, A; Namjou, S; Caidan, S; Gavrielides, M; MacRae, JI; Kelly, G; Peat, K; Kelly, D; Murra, A; Kelly, K; O’Flaherty, M; Dowdie, L; Ash, N; Gronthoud, F; Shea, RL; Gardner, G; Murray, D; Kinnaird, F; Cui, W; Pascual, J; Rodney, S; Mencel, J; Curtis, O; Stephenson, C; Robinson, A; Oza, B; Farag, S; Leslie, I; Rogiers, A; Iyengar, S; Ethell, M; Messiou, C; Cunningham, D; Chau, I; Starling, N; Turner, N; Welsh, L; van As, N; Jones, RL; Droney, J; Banerjee, S; Tatham, KC; O’Brien, M; Harrington, K; Bhide, S; Okines, A; Reid, A; Young, K; Furness, AJS; Pickering, L; Swanton, C; Gandhi, S; Gamblin, S; Bauer, DLV; Kassiotis, G; Kumar, S; Yousaf, N; Jhanji, S; Nicholson, E; Howell, M; Walker, S; Wilkinson, RJ; Larkin, J; Turajlic, S; - view fewer (2021) Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study. Nature Cancer 10.1038/s43018-021-00274-w. (In press).

Frankell, Alexander M; Dietzen, Michelle; Al Bakir, Maise; Lim, Emilia L; Karasaki, Takahiro; Ward, Sophia; Veeriah, Selvaraju; ... Swanton, Charles; + view all Frankell, Alexander M; Dietzen, Michelle; Al Bakir, Maise; Lim, Emilia L; Karasaki, Takahiro; Ward, Sophia; Veeriah, Selvaraju; Colliver, Emma; Huebner, Ariana; Bunkum, Abigail; Hill, Mark S; Grigoriadis, Kristiana; Moore, David A; Black, James RM; Liu, Wing Kin; Thol, Kerstin; Pich, Oriol; Watkins, Thomas BK; Naceur-Lombardelli, Cristina; Cook, Daniel E; Salgado, Roberto; Wilson, Gareth A; Bailey, Chris; Angelova, Mihaela; Bentham, Robert; Martinez-Ruiz, Carlos; Abbosh, Christopher; Nicholson, Andrew G; Le Quesne, John; Biswas, Dhruva; Rosenthal, Rachel; Puttick, Clare; Hessey, Sonya; Lee, Claudia; Prymas, Paulina; Toncheva, Antonia; Smith, Jon; Xing, Wei; Nicod, Jerome; Price, Gillian; Kerr, Keith M; Naidu, Babu; Middleton, Gary; Blyth, Kevin G; Fennell, Dean A; Forster, Martin D; Lee, Siow Ming; Falzon, Mary; Hewish, Madeleine; Shackcloth, Michael J; Lim, Eric; Benafif, Sarah; Russell, Peter; Boleti, Ekaterini; Krebs, Matthew G; Lester, Jason F; Papadatos-Pastos, Dionysis; Ahmad, Tanya; Thakrar, Ricky M; Lawrence, David; Navani, Neal; Janes, Sam M; Dive, Caroline; Blackhall, Fiona H; Summers, Yvonne; Cave, Judith; Marafioti, Teresa; Herrero, Javier; Quezada, Sergio A; Peggs, Karl S; Schwarz, Roland F; Van Loo, Peter; Miedema, Daniel M; Birkbak, Nicolai J; Hiley, Crispin T; Hackshaw, Allan; Zaccaria, Simone; Jamal-Hanjani, Mariam; McGranahan, Nicholas; Swanton, Charles; - view fewer (2024) The evolution of lung cancer and impact of subclonal selection in TRACERx (vol 616, pg 525, 2023). [Corrigendum]. Nature , 631 , Article E15. 10.1038/s41586-024-07738-w.

Frankell, AM; Dietzen, M; Al Bakir, M; Lim, EL; Karasaki, T; Ward, S; Veeriah, S; ... Gilbert, K; + view all Frankell, AM; Dietzen, M; Al Bakir, M; Lim, EL; Karasaki, T; Ward, S; Veeriah, S; Colliver, E; Huebner, A; Bunkum, A; Hill, MS; Grigoriadis, K; Moore, DA; Black, JRM; Liu, WK; Thol, K; Pich, O; Watkins, TBK; Naceur-Lombardelli, C; Cook, DE; Salgado, R; Wilson, GA; Bailey, C; Angelova, M; Bentham, R; Martínez-Ruiz, C; Abbosh, C; Nicholson, AG; Le Quesne, J; Biswas, D; Rosenthal, R; Puttick, C; Hessey, S; Lee, C; Prymas, P; Toncheva, A; Smith, J; Xing, W; Nicod, J; Price, G; Kerr, KM; Naidu, B; Middleton, G; Blyth, KG; Fennell, DA; Forster, MD; Lee, SM; Falzon, M; Hewish, M; Shackcloth, MJ; Lim, E; Benafif, S; Russell, P; Boleti, E; Krebs, MG; Lester, JF; Papadatos-Pastos, D; Ahmad, T; Thakrar, RM; Lawrence, D; Navani, N; Janes, SM; Dive, C; Blackhall, FH; Summers, Y; Cave, J; Marafioti, T; Herrero, J; Quezada, SA; Peggs, KS; Schwarz, RF; Van Loo, P; Miedema, DM; Birkbak, NJ; Hiley, CT; Hackshaw, A; Zaccaria, S; Le Quesne, J; Van Loo, P; Bajaj, A; Nakas, A; Sodha-Ramdeen, A; Ang, K; Tufail, M; Chowdhry, MF; Scotland, M; Boyles, R; Rathinam, S; Wilson, C; Marrone, D; Dulloo, S; Matharu, G; Shaw, JA; Riley, J; Primrose, L; Cheyne, H; Khalil, M; Richardson, S; Cruickshank, T; Gilbert, K; - view fewer (2023) The evolution of lung cancer and impact of subclonal selection in TRACERx. Nature , 616 pp. 525-533. 10.1038/s41586-023-05783-5.

Fu, X; Zhao, Y; Lopez, JI; Rowan, A; Au, L; Fendler, A; Hazell, S; ... Bates, PA; + view all Fu, X; Zhao, Y; Lopez, JI; Rowan, A; Au, L; Fendler, A; Hazell, S; Xu, H; Horswell, S; Shepherd, STC; Spencer, CE; Spain, L; Byrne, F; Stamp, G; O'Brien, T; Nicol, D; Augustine, M; Chandra, A; Rudman, S; Toncheva, A; Furness, AJS; Pickering, L; Kumar, S; Koh, D-M; Messiou, C; ap Dafydd, D; Orton, MR; Doran, SJ; Larkin, J; Swanton, C; Sahai, E; Litchfield, K; Turajlic, S; Bates, PA; - view fewer (2021) Spatial patterns of tumour growth impact clonal diversification in a computational model and the TRACERx Renal study. Nature Ecology & Evolution 10.1038/s41559-021-01586-x.

Ghorani, E; Reading, JL; Henry, JY; Massy, MRD; Rosenthal, R; Turati, V; Joshi, K; ... Quezada, SA; + view all Ghorani, E; Reading, JL; Henry, JY; Massy, MRD; Rosenthal, R; Turati, V; Joshi, K; Furness, AJS; Ben Aissa, A; Saini, SK; Ramskov, S; Georgiou, A; Sunderland, MW; Wong, YNS; Mucha, MVD; Day, W; Galvez-Cancino, F; Becker, PD; Uddin, I; Oakes, T; Ismail, M; Ronel, T; Woolston, A; Jamal-Hanjani, M; Veeriah, S; Birkbak, NJ; Wilson, GA; Litchfield, K; Conde, L; Guerra-Assunção, JA; Blighe, K; Biswas, D; Salgado, R; Lund, T; Bakir, MA; Moore, DA; Hiley, CT; Loi, S; Sun, Y; Yuan, Y; AbdulJabbar, K; Turajilic, S; Herrero, J; Enver, T; Hadrup, SR; Hackshaw, A; Peggs, KS; McGranahan, N; Chain, B; Swanton, C; Quezada, SA; - view fewer (2020) The T cell differentiation landscape is shaped by tumour mutations in lung cancer. Nature Cancer , 1 (5) pp. 546-561. 10.1038/s43018-020-0066-y.

Ghorani, E; Rosenthal, R; McGranahan, N; Reading, JL; Lynch, M; Peggs, KS; Swanton, C; Ghorani, E; Rosenthal, R; McGranahan, N; Reading, JL; Lynch, M; Peggs, KS; Swanton, C; Quezada, SA; - view fewer (2018) Differential binding affinity of mutated peptides for MHC class I is a predictor of survival in advanced lung cancer and melanoma. Annals of Oncology , 29 (1) pp. 271-279. 10.1093/annonc/mdx687.

Goh, G; Schmid, R; Guiver, K; Arpornwirat, W; Chitapanarux, I; Ganju, V; Im, SA; ... Swanton, C; + view all Goh, G; Schmid, R; Guiver, K; Arpornwirat, W; Chitapanarux, I; Ganju, V; Im, SA; Kim, SB; Dechaphunkul, A; Maneechavakajorn, J; Spector, N; Yau, T; Afrit, M; Ahmed, SB; Johnston, SR; Gibson, N; Uttenreuther-Fischer, M; Herrero, J; Swanton, C; - view fewer (2016) Clonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- Vinorelbine. PLOS Med , 13 (12) , Article e1002136. 10.1371/journal.pmed.1002136.

Greenwood, Hannah E; Barber, Abigail R; Edwards, Richard S; Tyrrell, Will E; George, Madeleine E; Dos Santos, Sofia N; Baark, Friedrich; ... Witney, Timothy H; + view all Greenwood, Hannah E; Barber, Abigail R; Edwards, Richard S; Tyrrell, Will E; George, Madeleine E; Dos Santos, Sofia N; Baark, Friedrich; Tanc, Muhammet; Khalil, Eman; Falzone, Aimee; Ward, Nathan P; Deblasi, Janine M; Torrente, Laura; Soni, Pritin N; Pearce, David R; Firth, George; Smith, Lydia M; Timmermand, Oskar Vilhelmsson; Huebner, Ariana; Swanton, Charles; Hynds, Robert E; Denicola, Gina M; Witney, Timothy H; - view fewer (2024) Imaging NRF2 activation in non-small cell lung cancer with positron emission tomography. Nature Communications , 15 , Article 10484. 10.1038/s41467-024-54852-4.

Grey, William; Rio-Machin, Ana; Casado, Pedro; Grönroos, Eva; Ali, Sara; Miettinen, Juho J; Bewicke-Copley, Findlay; ... Bonnet, Dominique; + view all Grey, William; Rio-Machin, Ana; Casado, Pedro; Grönroos, Eva; Ali, Sara; Miettinen, Juho J; Bewicke-Copley, Findlay; Parsons, Alun; Heckman, Caroline A; Swanton, Charles; Cutillas, Pedro R; Gribben, John; Fitzgibbon, Jude; Bonnet, Dominique; - view fewer (2022) CKS1 inhibition depletes leukemic stem cells and protects healthy hematopoietic stem cells in acute myeloid leukemia. Science Translational Medicine , 14 (650) , Article eabn3248. 10.1126/scitranslmed.abn3248.

Grigoriadis, Kristiana; Huebner, Ariana; Bunkum, Abigail; Colliver, Emma; Frankell, Alexander M; Hill, Mark S; Thol, Kerstin; ... McGranahan, Nicholas; + view all Grigoriadis, Kristiana; Huebner, Ariana; Bunkum, Abigail; Colliver, Emma; Frankell, Alexander M; Hill, Mark S; Thol, Kerstin; Birkbak, Nicolai J; Swanton, Charles; Zaccaria, Simone; McGranahan, Nicholas; - view fewer (2024) CONIPHER: a computational framework for scalable phylogenetic reconstruction with error correction. Nature Protocols , 19 pp. 159-183. 10.1038/s41596-023-00913-9.

Hainsworth, JD; Meric-Bernstam, F; Swanton, C; Hurwitz, H; Spigel, DR; Sweeney, C; Burris, H; ... Kurzrock, R; + view all Hainsworth, JD; Meric-Bernstam, F; Swanton, C; Hurwitz, H; Spigel, DR; Sweeney, C; Burris, H; Bose, R; Yoo, B; Stein, A; Beattie, M; Kurzrock, R; - view fewer (2018) Targeted Therapy for Advanced Solid Tumors on the Basis of Molecular Profiles: Results From MyPathway, an Open-Label, Phase IIa Multiple Basket Study. Journal of Clinical Oncology , 36 (6) pp. 536-544. 10.1200/JCO.2017.75.3780.

Han, G; Yang, G; Hao, D; Lu, Y; Thein, K; Simpson, BS; Chen, J; ... Wang, L; + view all Han, G; Yang, G; Hao, D; Lu, Y; Thein, K; Simpson, BS; Chen, J; Sun, R; Alhalabi, O; Wang, R; Dang, M; Dai, E; Zhang, S; Nie, F; Zhao, S; Guo, C; Hamza, A; Czerniak, B; Cheng, C; Siefker-Radtke, A; Bhat, K; Futreal, A; Peng, G; Wargo, J; Peng, W; Kadara, H; Ajani, J; Swanton, C; Litchfield, K; Ahnert, JR; Gao, J; Wang, L; - view fewer (2021) 9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapy. Nature Communications , 12 , Article 5606. 10.1038/s41467-021-25894-9.

Hasan, AM Mahedi; Cremaschi, Paolo; Wetterskog, Daniel; Jayaram, Anuradha; Wong, Stephen Q; Williams, Scott; Pasam, Anupama; ... Attard, Gerhardt; + view all Hasan, AM Mahedi; Cremaschi, Paolo; Wetterskog, Daniel; Jayaram, Anuradha; Wong, Stephen Q; Williams, Scott; Pasam, Anupama; Trigos, Anna; Trujillo, Blanca; Grist, Emily; Friedrich, Stefanie; Vainauskas, Osvaldas; Parry, Marina; Ismail, Mazlina; Devlies, Wout; Wingate, Anna; Linch, Mark; Naceur-Lombardelli, Cristina; PEACE consortium; Swanton, Charles; Jamal-Hanjani, Mariam; Lise, Stefano; Sandhu, Shahneen; Attard, Gerhardt; - view fewer (2023) Copy number architectures define treatment-mediated selection of lethal prostate cancer clones. Nature Communications , 14 , Article 4823. 10.1038/s41467-023-40315-9.

Hellewell, J; Russell, TW; SAFER Investigators and Field Study Team, ,; Crick COVID-19 Consortium, ,; CMMID COVID-19 working group, ,; Beale, R; Kelly, G; ... Kucharski, AJ; + view all Hellewell, J; Russell, TW; SAFER Investigators and Field Study Team, ,; Crick COVID-19 Consortium, ,; CMMID COVID-19 working group, ,; Beale, R; Kelly, G; Houlihan, C; Nastouli, E; Kucharski, AJ; - view fewer (2021) Estimating the effectiveness of routine asymptomatic PCR testing at different frequencies for the detection of SARS-CoV-2 infections. BMC Medicine , 19 (1) , Article 106. 10.1186/s12916-021-01982-x.

Hellmann, MD; Nathanson, T; Rizvi, H; Creelan, BC; Sanchez-Vega, F; Ahuja, A; Ni, A; ... Wolchok, JD; + view all Hellmann, MD; Nathanson, T; Rizvi, H; Creelan, BC; Sanchez-Vega, F; Ahuja, A; Ni, A; Novik, JB; Mangarin, LMB; Abu-Akeel, M; Liu, C; Sauter, JL; Rekhtman, N; Chang, E; Callahan, MK; Chaft, JE; Voss, MH; Tenet, M; Li, X-M; Covello, K; Renninger, A; Vitazka, P; Geese, WJ; Borghaei, H; Rudin, CM; Antonia, SJ; Swanton, C; Hammerbacher, J; Merghoub, T; McGranahan, N; Snyder, A; Wolchok, JD; - view fewer (2018) Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer. Cancer Cell , 33 (5) 843-852.e4. 10.1016/j.ccell.2018.03.018.

Hessey, Sonya; Fessas, Petros; Zaccaria, Simone; Jamal-Hanjani, Mariam; Swanton, Charles; (2023) Insights into the metastatic cascade through research autopsies. Trends Cancer 10.1016/j.trecan.2023.03.002.

Hiley, CT; Le Quesne, J; Santis, G; Sharpe, R; De Castro, DG; Middleton, G; Swanton, C; (2016) Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease. The Lancet , 388 (10048) pp. 1002-1011. 10.1016/S0140-6736(16)31340-X.

Hill, William; Weeden, Clare E; Swanton, Charles; (2024) Tumor Promoters and Opportunities for Molecular Cancer Prevention. Cancer Discovery , 14 (7) pp. 1154-1160. 10.1158/2159-8290.CD-24-0128.

Hobor, S; Al Bakir, M; Hiley, CT; Skrzypski, M; Frankell, AM; Bakker, B; Watkins, TBK; ... Clipson, A; + view all Hobor, S; Al Bakir, M; Hiley, CT; Skrzypski, M; Frankell, AM; Bakker, B; Watkins, TBK; Markovets, A; Dry, JR; Brown, AP; van der Aart, J; van den Bos, H; Spierings, D; Oukrif, D; Novelli, M; Chakrabarti, T; Rabinowitz, AH; Ait Hassou, L; Litière, S; Kerr, DL; Tan, L; Kelly, G; Moore, DA; Renshaw, MJ; Venkatesan, S; Hill, W; Huebner, A; Martínez-Ruiz, C; Black, JRM; Wu, W; Angelova, M; McGranahan, N; Downward, J; Chmielecki, J; Barrett, C; Litchfield, K; Chew, SK; Blakely, CM; de Bruin, EC; Foijer, F; Vousden, KH; Bivona, TG; Lester, JF; Bajaj, A; Nakas, A; Sodha-Ramdeen, A; Tufail, M; Scotland, M; Boyles, R; Rathinam, S; Wilson, C; Marrone, D; Dulloo, S; Fennell, DA; Matharu, G; Shaw, JA; Boleti, E; Cheyne, H; Khalil, M; Richardson, S; Cruickshank, T; Price, G; Kerr, KM; Benafif, S; French, J; Gilbert, K; Naidu, B; Patel, AJ; Osman, A; Enstone, C; Langman, G; Shackleford, H; Djearaman, M; Kadiri, S; Middleton, G; Leek, A; Hodgkinson, JD; Totton, N; Montero, A; Smith, E; Fontaine, E; Granato, F; Paiva-Correia, A; Novasio, J; Rammohan, K; Joseph, L; Bishop, P; Shah, R; Moss, S; Joshi, V; Crosbie, PAJ; Brown, KD; Carter, M; Chaturvedi, A; Oliveira, P; Lindsay, CR; Blackhall, FH; Krebs, MG; Summers, Y; Clipson, A; - view fewer (2024) Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature Communications , 15 , Article 4871. 10.1038/s41467-024-47606-9.

Houlihan, CF; Vora, N; Byrne, T; Lewer, D; Kelly, G; Heaney, J; Gandhi, S; ... SAFER Investigators; + view all Houlihan, CF; Vora, N; Byrne, T; Lewer, D; Kelly, G; Heaney, J; Gandhi, S; Spyer, MJ; Beale, R; Cherepanov, P; Moore, D; Gilson, R; Gamblin, S; Kassiotis, G; McCoy, LE; Swanton, C; Crick COVID-19 Consortium; Hayward, A; Nastouli, E; SAFER Investigators; - view fewer (2020) Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers. The Lancet , 396 (10246) e6-e7. 10.1016/S0140-6736(20)31484-7.

Hsieh, JJ; Purdue, MP; Signoretti, S; Swanton, C; Albiges, L; Schmidinger, M; Heng, DY; ... Ficarra, V; + view all Hsieh, JJ; Purdue, MP; Signoretti, S; Swanton, C; Albiges, L; Schmidinger, M; Heng, DY; Larkin, J; Ficarra, V; - view fewer (2017) Renal cell carcinoma. Nature Reviews Disease Primers , 3 , Article 17009. 10.1038/nrdp.2017.9.

Hudeček, J; Voorwerk, L; van Seijen, M; Nederlof, I; de Maaker, M; van den Berg, J; van de Vijver, KK; ... Peale, F; + view all Hudeček, J; Voorwerk, L; van Seijen, M; Nederlof, I; de Maaker, M; van den Berg, J; van de Vijver, KK; Sikorska, K; Adams, S; Demaria, S; Viale, G; Nielsen, TO; Badve, SS; Michiels, S; Symmans, WF; Sotiriou, C; Rimm, DL; Hewitt, SM; Denkert, C; Loibl, S; Loi, S; Bartlett, JMS; Pruneri, G; Dillon, DA; Cheang, MCU; Tutt, A; Hall, JA; Kos, Z; Salgado, R; Kok, M; Horlings, HM; Hyytiäinen, A; Hida, AI; Thompson, A; Lefevre, A; Lazar, AJ; Gown, A; Lo, A; Sapino, A; Madabhushi, A; Moreira, A; Richardson, A; Vingiani, A; Beck, AH; Bellizzi, AM; Guerrero, A; Grigoriadis, A; Ehinger, A; Garrido-Castro, A; Vincent-Salomon, A; Laenkholm, AV; Sharma, A; Cimino-Mathews, A; Srinivasan, A; Acs, B; Singh, B; Calhoun, B; Haibe-Kans, B; Solomon, B; Thapa, B; Nelson, BH; Gallas, BD; Castaneda, C; Ballesteros-Merino, C; Criscitiello, C; Boeckx, C; Colpaert, C; Quinn, C; Chennubhotla, CS; Swanton, C; Solinas, C; Hiley, C; Drubay, D; Bethmann, D; Moore, DA; Larsimont, D; Sabanathan, D; Peeters, D; Zardavas, D; Höflmayer, D; Johnson, DB; Thompson, EA; Brogi, E; Perez, E; ElGabry, EA; Stovgaard, ES; Blackley, EF; Roblin, E; Reisenbichler, E; Bellolio, E; Balslev, E; Chmielik, E; Gaire, F; Andre, F; Lu, FI; Azmoudeh-Ardalan, F; Rojo, F; Gruosso, T; Ciompi, F; Peale, F; - view fewer (2020) Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials. npj Breast Cancer , 6 , Article 15. 10.1038/s41523-020-0155-1.

Hung, King L; Luebeck, Jens; Dehkordi, Siavash R; Colón, Caterina I; Li, Rui; Wong, Ivy Tsz-Lo; Coruh, Ceyda; ... Chang, Howard Y; + view all Hung, King L; Luebeck, Jens; Dehkordi, Siavash R; Colón, Caterina I; Li, Rui; Wong, Ivy Tsz-Lo; Coruh, Ceyda; Dharanipragada, Prashanthi; Lomeli, Shirley H; Weiser, Natasha E; Moriceau, Gatien; Zhang, Xiao; Bailey, Chris; Houlahan, Kathleen E; Yang, Wenting; González, Rocío Chamorro; Swanton, Charles; Curtis, Christina; Jamal-Hanjani, Mariam; Henssen, Anton G; Law, Julie A; Greenleaf, William J; Lo, Roger S; Mischel, Paul S; Bafna, Vineet; Chang, Howard Y; - view fewer (2022) Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH. Nature Genetics 10.1038/s41588-022-01190-0. (In press).

Huntley, C; Torr, B; Sud, A; Rowlands, CF; Way, R; Snape, K; Hanson, H; ... Turnbull, C; + view all Huntley, C; Torr, B; Sud, A; Rowlands, CF; Way, R; Snape, K; Hanson, H; Swanton, C; Broggio, J; Lucassen, A; McCartney, M; Houlston, RS; Hingorani, AD; Jones, ME; Turnbull, C; - view fewer (2023) Utility of polygenic risk scores in UK cancer screening: a modelling analysis. The Lancet Oncology , 24 (6) pp. 658-668. 10.1016/S1470-2045(23)00156-0.

Hynds, Robert E; Huebner, Ariana; Pearce, David R; Hil, Mark S; Akarca, Ayse U; Moore, David A; Ward, Sophia; ... Swanton, Charles; + view all Hynds, Robert E; Huebner, Ariana; Pearce, David R; Hil, Mark S; Akarca, Ayse U; Moore, David A; Ward, Sophia; Gowers, Kate HC; Karasaki, Takahiro; Al Bakir, Maise; Wilson, Gareth A; Pich, Oriol; Martinez-Ruiz, Carlos; Hossain, AS Md Mukarram; Pearce, Simon P; Sivakumar, Monica; Ben Aissa, Assma; Gronroos, Eva; Chandrasekharan, Deepak; Kolluri, Krishna K; Towns, Rebecca; Wang, Kaiwen; Cook, Daniel E; Bosshard-Carter, Leticia; Naceur-Lombardelli, Cristina; Rowan, Andrew J; Veeriah, Selvaraju; Litchfield, Kevin; Crosbie, Philip AJ; Dive, Caroline; Quezada, Sergio A; Janes, Sam M; Jamal-Hanjani, Mariam; Marafioti, Teresa; McGranahan, Nicholas; Swanton, Charles; - view fewer (2024) Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models. Nature Communications , 15 , Article 4653. 10.1038/s41467-024-47547-3.

Hynds, RE; Ben Aissa, A; Gowers, KHC; Watkins, TBK; Bosshard-Carter, L; Rowan, AJ; Veeriah, S; ... Janes, SM; + view all Hynds, RE; Ben Aissa, A; Gowers, KHC; Watkins, TBK; Bosshard-Carter, L; Rowan, AJ; Veeriah, S; Wilson, GA; Quezada, SA; Swanton, C; TRACERx consortium; Janes, SM; - view fewer (2018) Expansion of airway basal epithelial cells from primary human non-small cell lung cancer tumors. International Journal of Cancer , 143 (1) pp. 160-166. 10.1002/ijc.31383.

Hynds, RE; Frese, KK; Pearce, DR; Grönroos, E; Dive, C; Swanton, C; (2021) Progress towards non-small-cell lung cancer models that represent clinical evolutionary trajectories. Open Biology , 11 (1) , Article 200247. 10.1098/rsob.200247.

Jamal-Hanjani, M; Thanopoulou, E; Peggs, KS; Quezada, SA; Swanton, C; (2013) Tumour heterogeneity and immune-modulation. Curr Opin Pharmacol , 13 (4) 497 - 503. 10.1016/j.coph.2013.04.006.

Jamal-Hanjani, M; Wilson, GA; McGranahan, N; Birkbak, NJ; Watkins, TBK; Veeriah, S; Shafi, S; ... Swanton, C; + view all Jamal-Hanjani, M; Wilson, GA; McGranahan, N; Birkbak, NJ; Watkins, TBK; Veeriah, S; Shafi, S; Johnson, DH; Mitter, R; Rosenthal, R; Salm, M; Horswell, S; Escudero, M; Matthews, N; Rowan, A; Chambers, T; Moore, DA; Turajlic, S; Xu, H; Lee, S-M; Forster, MD; Ahmad, T; Hiley, CT; Abbosh, C; Falzon, M; Borg, E; Marafioti, T; Lawrence, D; Hayward, M; Kolvekar, S; Panagiotopoulos, N; Janes, SM; Thakrar, R; Ahmed, A; Blackhall, F; Summers, Y; Shah, R; Joseph, L; Quinn, AM; Crosbie, PA; Naidu, B; Middleton, G; Langman, G; Trotter, S; Nicolson, M; Remmen, H; Kerr, K; Chetty, M; Gomersall, L; Fennell, DA; Nakas, A; Rathinam, S; Anand, G; Khan, S; Russell, P; Ezhil, V; Ismail, B; Irvin-Sellers, M; Prakash, V; Lester, JF; Kornaszewska, M; Attanoos, R; Adams, H; Davies, H; Dentro, S; Taniere, P; O'Sullivan, B; Lowe, HL; Hartley, JA; Iles, N; Bell, H; Ngai, Y; Shaw, JA; Herrero, J; Szallasi, Z; Schwarz, RF; Stewart, A; Quezada, SA; Le Quesne, J; Van Loo, P; Dive, C; Hackshaw, A; Swanton, C; - view fewer (2017) Tracking the Evolution of Non-Small-Cell Lung Cancer. New England Journal of Medicine , 376 (22) pp. 2109-2121. 10.1056/NEJMoa1616288.

Jamshidi, A; Liu, MC; Klein, EA; Venn, O; Hubbell, E; Beausang, JF; Gross, S; ... Swanton, C; + view all Jamshidi, A; Liu, MC; Klein, EA; Venn, O; Hubbell, E; Beausang, JF; Gross, S; Melton, C; Fields, AP; Liu, Q; Zhang, N; Fung, ET; Kurtzman, KN; Amini, H; Betts, C; Civello, D; Freese, P; Calef, R; Davydov, K; Fayzullina, S; Hou, C; Jiang, R; Jung, B; Tang, S; Demas, V; Newman, J; Sakarya, O; Scott, E; Shenoy, A; Shojaee, S; Steffen, KK; Nicula, V; Chien, TC; Bagaria, S; Hunkapiller, N; Desai, M; Dong, Z; Richards, DA; Yeatman, TJ; Cohn, AL; Thiel, DD; Berry, DA; Tummala, MK; McIntyre, K; Sekeres, MA; Bryce, A; Aravanis, AM; Seiden, MV; Swanton, C; - view fewer (2022) Evaluation of cell-free DNA approaches for multi-cancer early detection. Cancer Cell , 40 (12) pp. 1537-1549. 10.1016/j.ccell.2022.10.022.

Joshi, K; Robert de Massy, M; Ismail, M; Reading, JL; Uddin, I; Woolston, A; Hatipoglu, E; ... Chain, B; + view all Joshi, K; Robert de Massy, M; Ismail, M; Reading, JL; Uddin, I; Woolston, A; Hatipoglu, E; Oakes, T; Rosenthal, R; Peacock, T; Ronel, T; Noursadeghi, M; Turati, V; Furness, AJS; Georgiou, A; Wong, YNS; Ben Aissa, A; Werner Sunderland, M; Jamal-Hanjani, M; Veeriah, S; Birkbak, NJ; Wilson, GA; Hiley, CT; Ghorani, E; Guerra-Assunção, JA; Herrero, J; Enver, T; Hadrup, SR; Hackshaw, A; Peggs, KS; McGranahan, N; Swanton, C; TRACERx Consortium, .; Quezada, SA; Chain, B; - view fewer (2019) Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer. Nature Medicine , 25 pp. 1549-1559. 10.1038/s41591-019-0592-2.

Kanu, N; Groenroos, E; Martinez, P; Burrell, RA; Goh, X Yi; Bartkova, J; Maya-Mendoza, A; ... Swanton, C; + view all Kanu, N; Groenroos, E; Martinez, P; Burrell, RA; Goh, X Yi; Bartkova, J; Maya-Mendoza, A; Mistrik, M; Rowan, AJ; Patel, H; Rabinowitz, A; East, P; Wilson, G; Santos, CR; McGranahan, N; Gulati, S; Gerlinger, M; Birkbak, NJ; Joshi, T; Alexandrov, LB; Stratton, MR; Powles, T; Matthews, N; Bates, PA; Stewart, A; Szallasi, Z; Larkin, J; Bartek, J; Swanton, C; - view fewer (2015) SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. Oncogene , 34 (46) pp. 5699-5708. 10.1038/onc.2015.24.

Kanu, N; Zhang, T; Burrell, RA; Chakraborty, A; Cronshaw, J; DaCosta, C; Grönroos, E; ... Behrens, A; + view all Kanu, N; Zhang, T; Burrell, RA; Chakraborty, A; Cronshaw, J; DaCosta, C; Grönroos, E; Pemberton, HN; Anderton, E; Gonzalez, L; Sabbioneda, S; Ulrich, HD; Swanton, C; Behrens, A; - view fewer (2015) RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress. Oncogene , 35 (30) pp. 4009-4019. 10.1038/onc.2015.427.

Kanu, Nnennaya; Lu, Wei-Ting; Swanton, Charles; Bartek, Jiri; (2025) TRACERx analysis identifies a role for FAT1 in regulating chromosomal instability and whole-genome doubling via Hippo signalling. Nature Cell Biology , 27 (1) pp. 154-168. 10.1038/s41556-024-01558-w.

Kanu, N; Cerone, MA; Goh, G; Zalmas, L-P; Bartkova, J; Dietzen, M; McGranahan, N; ... Swanton, C; + view all Kanu, N; Cerone, MA; Goh, G; Zalmas, L-P; Bartkova, J; Dietzen, M; McGranahan, N; Rogers, R; Law, EK; Gromova, I; Kschischo, M; Walton, MI; Rossanese, OW; Bartek, J; Harris, RS; Venkatesan, S; Swanton, C; - view fewer (2016) DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer. Genome Biology , 17 , Article 185. 10.1186/s13059-016-1042-9.

Kaufmann, Tom L; Petkovic, Marina; Watkins, Thomas BK; Colliver, Emma C; Laskina, Sofya; Thapa, Nisha; Minussi, Darlan C; ... Schwarz, Roland F; + view all Kaufmann, Tom L; Petkovic, Marina; Watkins, Thomas BK; Colliver, Emma C; Laskina, Sofya; Thapa, Nisha; Minussi, Darlan C; Navin, Nicholas; Swanton, Charles; Van Loo, Peter; Haase, Kerstin; Tarabichi, Maxime; Schwarz, Roland F; - view fewer (2022) MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution. Genome Biology volume , 23 , Article 241. 10.1186/s13059-022-02794-9.

Kim, YJ; Sheu, KM; Tsoi, J; Abril-Rodriguez, G; Medina, E; Grasso, CS; Torrejon, DY; ... Ribas, A; + view all Kim, YJ; Sheu, KM; Tsoi, J; Abril-Rodriguez, G; Medina, E; Grasso, CS; Torrejon, DY; Champhekar, AS; Litchfield, K; Swanton, C; Speiser, DE; Scumpia, PO; Hoffmann, A; Graeber, TG; Puig-Saus, C; Ribas, A; - view fewer (2021) Melanoma dedifferentiation induced by IFN-γ epigenetic remodeling in response to anti–PD-1 therapy. The Journal of Clinical Investigation , 131 (12) , Article e145859. 10.1172/JCI145859.

Klein, EA; Richards, D; Cohn, A; Tummala, M; Lapham, R; Cosgrove, D; Chung, G; ... Liu, MC; + view all Klein, EA; Richards, D; Cohn, A; Tummala, M; Lapham, R; Cosgrove, D; Chung, G; Clement, J; Gao, J; Hunkapiller, N; Jamshidi, A; Kurtzman, KN; Seiden, MV; Swanton, C; Liu, MC; - view fewer (2021) Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set. Annals of Oncology 10.1016/j.annonc.2021.05.806. (In press).

Kos, Z; Roblin, E; Kim, RS; Michiels, S; Gallas, BD; Chen, W; van de Vijver, KK; ... International Immuno-Oncology Biomarker Working Group; + view all Kos, Z; Roblin, E; Kim, RS; Michiels, S; Gallas, BD; Chen, W; van de Vijver, KK; Goel, S; Adams, S; Demaria, S; Viale, G; Nielsen, TO; Badve, SS; Symmans, WF; Sotiriou, C; Rimm, DL; Hewitt, S; Denkert, C; Loibl, S; Luen, SJ; Bartlett, JMS; Savas, P; Pruneri, G; Dillon, DA; Cheang, MCU; Tutt, A; Hall, JA; Kok, M; Horlings, HM; Madabhushi, A; van der Laak, J; Ciompi, F; Laenkholm, A-V; Bellolio, E; Gruosso, T; Fox, SB; Araya, JC; Floris, G; Hudeček, J; Voorwerk, L; Beck, AH; Kerner, J; Larsimont, D; Declercq, S; Van den Eynden, G; Pusztai, L; Ehinger, A; Yang, W; AbdulJabbar, K; Yuan, Y; Singh, R; Hiley, C; Bakir, MA; Lazar, AJ; Naber, S; Wienert, S; Castillo, M; Curigliano, G; Dieci, M-V; André, F; Swanton, C; Reis-Filho, J; Sparano, J; Balslev, E; Chen, I-C; Stovgaard, EIS; Pogue-Geile, K; Blenman, KRM; Penault-Llorca, F; Schnitt, S; Lakhani, SR; Vincent-Salomon, A; Rojo, F; Braybrooke, JP; Hanna, MG; Soler-Monsó, MT; Bethmann, D; Castaneda, CA; Willard-Gallo, K; Sharma, A; Lien, H-C; Fineberg, S; Thagaard, J; Comerma, L; Gonzalez-Ericsson, P; Brogi, E; Loi, S; Saltz, J; Klaushen, F; Cooper, L; Amgad, M; Moore, DA; Salgado, R; International Immuno-Oncology Biomarker Working Group; - view fewer (2020) Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer. NPJ Breast Cancer , 6 , Article 17. 10.1038/s41523-020-0156-0.

Kurzrock, R; Bowles, DW; Kang, H; Meric-Bernstam, F; Hainsworth, J; Spigel, DR; Bose, R; ... Swanton, C; + view all Kurzrock, R; Bowles, DW; Kang, H; Meric-Bernstam, F; Hainsworth, J; Spigel, DR; Bose, R; Burris, H; Sweeney, CJ; Beattie, MS; Blotner, S; Schulze, K; Cuchelkar, V; Swanton, C; - view fewer (2020) Targeted therapy for advanced salivary gland carcinoma based on molecular profiling: results from MyPathway, a phase IIa multiple basket study. Annals of Oncology , 31 (3) pp. 412-421. 10.1016/j.annonc.2019.11.018.

Lange, Joshua T; Rose, John C; Chen, Celine Y; Pichugin, Yuriy; Xie, Liangqi; Tang, Jun; Hung, King L; ... Mischel, Paul S; + view all Lange, Joshua T; Rose, John C; Chen, Celine Y; Pichugin, Yuriy; Xie, Liangqi; Tang, Jun; Hung, King L; Yost, Kathryn E; Shi, Quanming; Erb, Marcella L; Rajkumar, Utkrisht; Wu, Sihan; Taschner-Mandl, Sabine; Bernkopf, Marie; Swanton, Charles; Liu, Zhe; Huang, Weini; Chang, Howard Y; Bafna, Vineet; Henssen, Anton G; Werner, Benjamin; Mischel, Paul S; - view fewer (2022) The evolutionary dynamics of extrachromosomal DNA in human cancers. Nature Genetics 10.1038/s41588-022-01177-x. (In press).

Leung, Michelle M; Swanton, Charles; Mcgranahan, Nicholas; (2025) Integrating model systems and genomic insights to decipher mechanisms of cancer metastasis. Nature Reviews Genetics , 26 pp. 494-505. 10.1038/s41576-025-00825-2.

Li, J; Duran, MA; Dhanota, N; Chatila, WK; Bettigole, SE; Kwon, J; Sriram, RK; ... Bakhoum, SF; + view all Li, J; Duran, MA; Dhanota, N; Chatila, WK; Bettigole, SE; Kwon, J; Sriram, RK; Humphries, MP; Salto-Tellez, M; James, JA; Hanna, MG; Melms, JC; Vallabhaneni, S; Litchfield, K; Usaite, I; Biswas, D; Bareja, R; Li, HW; Martin, ML; Dorsaint, P; Cavallo, J-A; Li, P; Pauli, C; Gottesdiener, L; DiPardo, BJ; Hollmann, TJ; Merghoub, T; Wen, HY; Reis-Filho, JS; Riaz, N; Su, S-SM; Kalbasi, A; Vasan, N; Powell, SN; Wolchok, JD; Elemento, O; Swanton, C; Shoushtari, AN; Parkes, EE; Izar, B; Bakhoum, SF; - view fewer (2021) Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis. Cancer Discovery , 11 (5) pp. 1212-1227. 10.1158/2159-8290.CD-20-0387.

Linch, M; Goh, G; Hiley, C; Shanmugabavan, Y; McGranahan, N; Rowan, A; Wong, YNS; ... Swanton, C; + view all Linch, M; Goh, G; Hiley, C; Shanmugabavan, Y; McGranahan, N; Rowan, A; Wong, YNS; King, H; Furness, A; Freeman, A; Linares, J; Akarca, A; Herrero, J; Rosenthal, R; Harder, N; Schmidt, G; Wilson, GA; Birkbak, NJ; Mitter, R; Dentro, S; Cathcart, P; Arya, M; Johnston, E; Scott, R; Hung, M; Emberton, M; Attard, G; Szallasi, Z; Punwani, S; Quezada, SA; Marafioti, T; Gerlinger, M; Ahmed, HU; Swanton, C; - view fewer (2017) Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters. Annals of Oncology , 28 (10) pp. 2472-2480. 10.1093/annonc/mdx355.

Litchfield, K; Reading, JL; Lim, EL; Xu, H; Liu, P; Al-Bakir, M; Wong, YNS; ... Swanton, C; + view all Litchfield, K; Reading, JL; Lim, EL; Xu, H; Liu, P; Al-Bakir, M; Wong, YNS; Rowan, A; Funt, SA; Merghoub, T; Perkins, D; Lauss, M; Svane, IM; Jönsson, G; Herrero, J; Larkin, J; Quezada, SA; Hellmann, MD; Turajlic, S; Swanton, C; - view fewer (2020) Escape from nonsense-mediated decay associates with anti-tumor immunogenicity. Nature Communications , 11 , Article 3800. 10.1038/s41467-020-17526-5.

Litchfield, K; Reading, JL; Puttick, C; Thakkar, K; Abbosh, C; Bentham, R; Watkins, TBK; ... Swanton, C; + view all Litchfield, K; Reading, JL; Puttick, C; Thakkar, K; Abbosh, C; Bentham, R; Watkins, TBK; Rosenthal, R; Biswas, D; Rowan, A; Lim, E; Al Bakir, M; Turati, V; Guerra-Assunção, JA; Conde, L; Furness, AJS; Saini, SK; Hadrup, SR; Herrero, J; Lee, S-H; Van Loo, P; Enver, T; Larkin, J; Hellmann, MD; Turajlic, S; Quezada, SA; McGranahan, N; Swanton, C; - view fewer (2021) Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition. Cell , 184 (3) 596-614.e14. 10.1016/j.cell.2021.01.002.

Litchfield, K; Stanislaw, S; Spain, L; Gallegos, LL; Rowan, A; Schnidrig, D; Rosenbaum, H; ... Turajlic, S; + view all Litchfield, K; Stanislaw, S; Spain, L; Gallegos, LL; Rowan, A; Schnidrig, D; Rosenbaum, H; Harle, A; Au, L; Hill, SM; Tippu, Z; Thomas, J; Thompson, L; Xu, H; Horswell, S; Barhoumi, A; Jones, C; Leith, KF; Burgess, DL; Watkins, TBK; Lim, E; Birkbak, NJ; Lamy, P; Nordentoft, I; Dyrskjøt, L; Pickering, L; Hazell, S; Jamal-Hanjani, M; PEACE Consortium; Larkin, J; Swanton, C; Alexander, NR; Turajlic, S; - view fewer (2020) Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue. Cell Reports , 31 (5) p. 107550. 10.1016/j.celrep.2020.107550.

Litchfield, K; Turajlic, S; Swanton, C; (2017) The GENIE Is Out of the Bottle: Landmark Cancer Genomics Dataset Released. Cancer Discovery , 7 (8) pp. 796-798. 10.1158/2159-8290.CD-17-0604.

Liu, MC; Oxnard, GR; Klein, EA; Swanton, C; Seiden, MV; CCGA Consortium, .; (2020) Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA. Annals of Oncology , 31 (6) pp. 745-759. 10.1016/j.annonc.2020.02.011.

Loennstedt, Ingrid M; Caramia, Franco; Li, Jason; Fumagalli, Debora; Salgado, Roberto; Rowan, Andrew; Salm, Max; ... Speed, Terence P; + view all Loennstedt, Ingrid M; Caramia, Franco; Li, Jason; Fumagalli, Debora; Salgado, Roberto; Rowan, Andrew; Salm, Max; Kanu, Nnennaya; Savas, Peter; Horswell, Stuart; Gade, Stephan; Loibl, Sibylle; Neven, Patrick; Sotiriou, Christos; Swanton, Charles; Loi, Sherene; Speed, Terence P; - view fewer (2014) Deciphering clonality in aneuploid breast tumors using SNP array and sequencing data. Genome Biology , 15 (9) , Article 470. 10.1186/s13059-014-0470-7.

López, S; Lim, EL; Horswell, S; Haase, K; Huebner, A; Dietzen, M; Mourikis, TP; ... McGranahan, N; + view all López, S; Lim, EL; Horswell, S; Haase, K; Huebner, A; Dietzen, M; Mourikis, TP; Watkins, TBK; Rowan, A; Dewhurst, SM; Birkbak, NJ; Wilson, GA; Van Loo, P; Jamal-Hanjani, M; TRACERx Consortium; Swanton, C; McGranahan, N; - view fewer (2020) Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution. Nature Genetics , 52 (3) pp. 283-293. 10.1038/s41588-020-0584-7.

Lopez-Garcia, C; Sansregret, L; Domingo, E; McGranahan, N; Hobor, S; Birkbak, NJ; Horswell, S; ... Swanton, C; + view all Lopez-Garcia, C; Sansregret, L; Domingo, E; McGranahan, N; Hobor, S; Birkbak, NJ; Horswell, S; Gronroos, E; Favero, F; Rowan, AJ; Matthews, N; Begum, S; Phillimore, B; Burrell, R; Oukrif, D; Spencer-Dene, B; Kovac, M; Stamp, G; Stewart, A; Danielsen, H; Novelli, M; Tomlinson, I; Swanton, C; - view fewer (2017) BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer. Cancer Cell , 31 (1) pp. 79-93. 10.1016/j.ccell.2016.11.001.

Loveday, C; Litchfield, K; Proszek, PZ; Cornish, AJ; Santo, F; Levy, M; Macintyre, G; ... Turnbull, C; + view all Loveday, C; Litchfield, K; Proszek, PZ; Cornish, AJ; Santo, F; Levy, M; Macintyre, G; Holryod, A; Broderick, P; Dudakia, D; Benton, B; Bakir, MA; Hiley, C; Grist, E; Swanton, C; Huddart, R; Powles, T; Chowdhury, S; Shipley, J; O'Connor, S; Brenton, JD; Reid, A; de Castro, DG; Houlston, RS; Turnbull, C; - view fewer (2020) Genomic landscape of platinum resistant and sensitive testicular cancers. Nature Communications , 11 , Article 2189. 10.1038/s41467-020-15768-x.

Lu, L; Teixeira, VH; Yuan, Z; Graham, TA; Endesfelder, D; Kolluri, K; Al-Juffali, N; ... Janes, SM; + view all Lu, L; Teixeira, VH; Yuan, Z; Graham, TA; Endesfelder, D; Kolluri, K; Al-Juffali, N; Hamilton, N; Nicholson, AG; Falzon, M; Kschischo, M; Swanton, C; Wright, NA; Carroll, B; Watt, FM; George, JP; Jensen, KB; Giangreco, A; Janes, SM; - view fewer (2013) LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development. J Pathol , 229 (4) 608 - 620. 10.1002/path.4148.

Lucas, Olivia; Ward, Sophia; Zaidi, Rija; Bunkum, Abigail; Frankell, Alexander M; Moore, David A; Hill, Mark S; ... Zaccaria, Simone; + view all Lucas, Olivia; Ward, Sophia; Zaidi, Rija; Bunkum, Abigail; Frankell, Alexander M; Moore, David A; Hill, Mark S; Liu, Wing Kin; Marinelli, Daniele; Lim, Emilia L; Hessey, Sonya; Naceur-Lombardelli, Cristina; Rowan, Andrew; Purewal-Mann, Sukhveer Kaur; Zhai, Haoran; Dietzen, Michelle; Ding, Boyue; Royle, Gary; Aparicio, Samuel; TRACERx Consortium; PEACE Consortium; McGranahan, Nicholas; Jamal-Hanjani, Mariam; Kanu, Nnennaya; Swanton, Charles; Zaccaria, Simone; - view fewer (2024) Characterizing the evolutionary dynamics of cancer proliferation in single-cell clones with SPRINTER. Nature Genetics 10.1038/s41588-024-01989-z. (In press).

Mackay, HL; Moore, D; Hall, C; Birkbak, NJ; Jamal-Hanjani, M; Karim, SA; Phatak, VM; ... Muller, PAJ; + view all Mackay, HL; Moore, D; Hall, C; Birkbak, NJ; Jamal-Hanjani, M; Karim, SA; Phatak, VM; Pinon, L; Morton, JP; Swanton, C; Le Quesne, J; Muller, PAJ; - view fewer (2018) Genomic instability in mutant p53 cancer cells upon entotic engulfment. Nature Communications , 9 , Article 3070. 10.1038/s41467-018-05368-1.

Maiani, E; Milletti, G; Nazio, F; Holdgaard, SG; Bartkova, J; Rizza, S; Cianfanelli, V; ... Cecconi, F; + view all Maiani, E; Milletti, G; Nazio, F; Holdgaard, SG; Bartkova, J; Rizza, S; Cianfanelli, V; Lorente, M; Simoneschi, D; Di Marco, M; D'Acunzo, P; Di Leo, L; Rasmussen, R; Montagna, C; Raciti, M; De Stefanis, C; Gabicagogeascoa, E; Rona, G; Salvador, N; Pupo, E; Merchut-Maya, JM; Daniel, CJ; Carinci, M; Cesarini, V; O'sullivan, A; Jeong, Y-T; Bordi, M; Russo, F; Campello, S; Gallo, A; Filomeni, G; Lanzetti, L; Sears, RC; Hamerlik, P; Bartolazzi, A; Hynds, RE; Pearce, DR; Swanton, C; Pagano, M; Velasco, G; Papaleo, E; De Zio, D; Maya-Mendoza, A; Locatelli, F; Bartek, J; Cecconi, F; - view fewer (2021) AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity. Nature , 592 (7856) pp. 799-803. 10.1038/s41586-021-03422-5.

Maley, CC; Aktipis, A; Graham, TA; Sottoriva, A; Boddy, AM; Janiszewska, M; Silva, AS; ... Shibata, D; + view all Maley, CC; Aktipis, A; Graham, TA; Sottoriva, A; Boddy, AM; Janiszewska, M; Silva, AS; Gerlinger, M; Yuan, Y; Pienta, KJ; Anderson, KS; Gatenby, R; Swanton, C; Posada, D; Wu, C-I; Schiffman, JD; Hwang, ES; Polyak, K; Anderson, ARA; Brown, JS; Greaves, M; Shibata, D; - view fewer (2017) Classifying the evolutionary and ecological features of neoplasms. Nature Reviews Cancer , 17 (10) pp. 605-619. 10.1038/nrc.2017.69.

Martins, Filipe Correia; Couturier, Dominique-Laurent; De Santiago, Ines; Sauer, Carolin Margarethe; Vias, Maria; Angelova, Mihaela; Sanders, Deborah; ... Brenton, James D; + view all Martins, Filipe Correia; Couturier, Dominique-Laurent; De Santiago, Ines; Sauer, Carolin Margarethe; Vias, Maria; Angelova, Mihaela; Sanders, Deborah; Piskorz, Anna; Hall, James; Hosking, Karen; Amirthanayagam, Anumithra; Cosulich, Sabina; Carnevalli, Larissa; Davies, Barry; Watkins, Thomas BK; Funingana, Ionut G; Bolton, Helen; Haldar, Krishnayan; Latimer, John; Baldwin, Peter; Crawford, Robin; Eldridge, Matthew; Basu, Bristi; Jimenez-Linan, Mercedes; Mcpherson, Andrew W; McGranahan, Nicholas; Litchfield, Kevin; Shah, Sohrab P; McNeish, Iain; Caldas, Carlos; Evan, Gerard; Swanton, Charles; Brenton, James D; - view fewer (2022) Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer. Nature Communications , 13 (1) , Article 6360. 10.1038/s41467-022-33870-0.

Mateo, J; Chakravarty, D; Dienstmann, R; Jezdic, S; Gonzalez-Perez, A; Lopez-Bigas, N; Ng, CKY; ... Pusztai, L; + view all Mateo, J; Chakravarty, D; Dienstmann, R; Jezdic, S; Gonzalez-Perez, A; Lopez-Bigas, N; Ng, CKY; Bedard, PL; Tortora, G; Douillard, J-Y; Van Allen, EM; Schultz, N; Swanton, C; André, F; Pusztai, L; - view fewer (2018) A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT). Annals of Oncology , 29 (9) pp. 1895-1902. 10.1093/annonc/mdy263.

McGranahan, N; Rosenthal, R; Hiley, CT; Rowan, AJ; Watkins, TBK; Wilson, GA; Birkbak, NJ; ... Swanton, C; + view all McGranahan, N; Rosenthal, R; Hiley, CT; Rowan, AJ; Watkins, TBK; Wilson, GA; Birkbak, NJ; Veeriah, S; Van Loo, P; Herrero, J; Swanton, C; - view fewer (2017) Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution. Cell 10.1016/j.cell.2017.10.001. (In press).

McGranahan, N; Swanton, C; (2019) Neoantigen quality, not quantity. Science Translational Medicine , 11 (506) , Article eaax7918. 10.1126/scitranslmed.aax7918.

McGranahan, N; Swanton, C; (2017) Cancer Evolution Constrained by the Immune Microenvironment. CELL , 170 (5) pp. 825-827. 10.1016/j.cell.2017.08.012.

McGranahan, N; Swanton, C; (2017) Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future. Cell , 168 (4) pp. 613-628. 10.1016/j.cell.2017.01.018.

Mears, HV; Young, GR; Sanderson, T; Harvey, R; Barrett-Rodger, J; Penn, R; Cowton, V; ... Bauer, DLV; + view all Mears, HV; Young, GR; Sanderson, T; Harvey, R; Barrett-Rodger, J; Penn, R; Cowton, V; Furnon, W; De Lorenzo, G; Crawford, M; Snell, DM; Fowler, AS; Chakrabarti, AM; Hussain, S; Gilbride, C; Emmott, E; Finsterbusch, K; Luptak, J; Peacock, TP; Nicod, J; Patel, AH; Palmarini, M; Wall, E; Williams, B; Gandhi, S; Swanton, C; Bauer, DLV; - view fewer (2025) Emergence of SARS-CoV-2 subgenomic RNAs that enhance viral fitness and immune evasion. PLoS Biology , 23 (1) , Article e3002982. 10.1371/journal.pbio.3002982.

Meric-Bernstam, F; Hurwitz, H; Raghav, KPS; McWilliams, RR; Fakih, M; VanderWalde, A; Swanton, C; ... Hainsworth, J; + view all Meric-Bernstam, F; Hurwitz, H; Raghav, KPS; McWilliams, RR; Fakih, M; VanderWalde, A; Swanton, C; Kurzrock, R; Burris, H; Sweeney, C; Bose, R; Spigel, DR; Beattie, MS; Blotner, S; Stone, A; Schulze, K; Cuchelkar, V; Hainsworth, J; - view fewer (2019) Pertuzumab plus trastuzumab for HER2-amplified metastatic colorectal cancer (MyPathway): an updated report from a multicentre, open-label, phase 2a, multiple basket study. Lancet Oncology , 20 (4) pp. 518-530. 10.1016/S1470-2045(18)30904-5.

Middleton, G; Fletcher, P; Popat, S; Savage, J; Summers, Y; Greystoke, A; Gilligan, D; ... Billingham, L; + view all Middleton, G; Fletcher, P; Popat, S; Savage, J; Summers, Y; Greystoke, A; Gilligan, D; Cave, J; O'Rourke, N; Brewster, A; Toy, E; Spicer, J; Jain, P; Dangoor, A; Mackean, M; Forster, M; Farley, A; Wherton, D; Mehmi, M; Sharpe, R; Mills, TC; Cerone, MA; Yap, TA; Watkins, TBK; Lim, E; Swanton, C; Billingham, L; - view fewer (2020) The National Lung Matrix Trial of personalized therapy in lung cancer. Nature , 583 (7818) pp. 807-812. 10.1038/s41586-020-2481-8.

Miller, RE; Brown, NE; Speirs, A; Shaw, HM; Adeleke, S; Gougis, P; Bennett, P; ... Kristeleit, RS; + view all Miller, RE; Brown, NE; Speirs, A; Shaw, HM; Adeleke, S; Gougis, P; Bennett, P; Meyer, T; Swanton, C; Forster, MD; Kristeleit, RS; - view fewer (2016) The use of next generation sequencing (NGS) to guide patient selection for phase 1 clinical trials. Annals of Oncology , 27 (Suppl 6) pp. 114-135. 10.1093/annonc/mdw368.44.

Mitchell, TJ; Turajlic, S; Rowan, A; Nicol, D; Farmery, JHR; O'Brien, T; Martincorena, I; ... Campbell, PJ; + view all Mitchell, TJ; Turajlic, S; Rowan, A; Nicol, D; Farmery, JHR; O'Brien, T; Martincorena, I; Tarpey, P; Angelopoulos, N; Yates, LR; Butler, AP; Raine, K; Stewart, GD; Challacombe, B; Fernando, A; Lopez, JI; Hazell, S; Chandra, A; Chowdhury, S; Rudman, S; Soultati, A; Stamp, G; Fotiadis, N; Pickering, L; Au, L; Spain, L; Lynch, J; Stares, M; Teague, J; Maura, F; Wedge, DC; Horswell, S; Chambers, T; Litchfield, K; Xu, H; Stewart, A; Elaidi, R; Oudard, S; McGranahan, N; Csabai, I; Gore, M; Futreal, PA; Larkin, J; Lynch, AG; Szallasi, Z; Swanton, C; Campbell, PJ; - view fewer (2018) Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal. Cell , 173 (3) , Article e17. 10.1016/j.cell.2018.02.020.

Molnar, Janos; Poti, Adam; Pipek, Orsolya; Krzystanek, Marcin; Kanu, Nnennaya; Swanton, Charles; Tusnady, Gabor E; ... Szuets, David; + view all Molnar, Janos; Poti, Adam; Pipek, Orsolya; Krzystanek, Marcin; Kanu, Nnennaya; Swanton, Charles; Tusnady, Gabor E; Szallasi, Zoltan; Csabai, Istvan; Szuets, David; - view fewer (2014) The Genome of the Chicken DT40 Bursal Lymphoma Cell Line. G3-GENES GENOMES GENETICS , 4 (11) pp. 2231-2240. 10.1534/g3.114.013482.

Montgomery, HE; Haines, A; Marlow, N; Pearson, G; Mythen, MG; Grocott, MPW; Swanton, C; (2017) The future of UK healthcare: problems and potential solutions to a system in crisis. [Review]. Annals of Oncology , 28 (8) pp. 1751-1755. 10.1093/annonc/mdx136.

Moore, DA; Kushnir, M; Mak, G; Winter, H; Curiel, T; Voskoboynik, M; Moschetta, M; ... Arkenau, HT; + view all Moore, DA; Kushnir, M; Mak, G; Winter, H; Curiel, T; Voskoboynik, M; Moschetta, M; Rozumna-Martynyuk, N; Balbi, K; Bennett, P; Forster, M; Kulkarni, A; Haynes, D; Swanton, C; Arkenau, HT; - view fewer (2019) Prospective analysis of 895 patients on a UK Genomics Review Board. ESMO Open , 4 (2) , Article e000469. 10.1136/esmoopen-2018-000469.

Morales Torres, C; Wu, MY; Hobor, S; Wainwright, EN; Martin, MJ; Patel, H; Grey, W; ... Scaffidi, P; + view all Morales Torres, C; Wu, MY; Hobor, S; Wainwright, EN; Martin, MJ; Patel, H; Grey, W; Grönroos, E; Howell, S; Carvalho, J; Snijders, AP; Bustin, M; Bonnet, D; Smith, PD; Swanton, C; Howell, M; Scaffidi, P; - view fewer (2020) Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis. Nature Communications , 11 (1) , Article 1792. 10.1038/s41467-020-15615-z.

Morrissy, AS; Cavalli, FMG; Remke, M; Ramaswamy, V; Shih, DJH; Holgado, BL; Farooq, H; ... Taylor, MD; + view all Morrissy, AS; Cavalli, FMG; Remke, M; Ramaswamy, V; Shih, DJH; Holgado, BL; Farooq, H; Donovan, LK; Garzia, L; Agnihotri, S; Kiehna, EN; Mercier, E; Mayoh, C; Papillon-Cavanagh, S; Nikbakht, H; Gayden, T; Torchia, J; Picard, D; Merino, DM; Vladoiu, M; Luu, B; Wu, X; Daniels, C; Horswell, S; Thompson, YY; Hovestadt, V; Northcott, PA; Jones, DTW; Peacock, J; Wang, X; Mack, SC; Reimand, J; Albrecht, S; Fontebasso, AM; Thiessen, N; Li, Y; Schein, JE; Lee, D; Carlsen, R; Mayo, M; Tse, K; Tam, A; Dhalla, N; Ally, A; Chuah, E; Cheng, Y; Plettner, P; Li, HI; Corbett, RD; Wong, T; Long, W; Loukides, J; Buczkowicz, P; Hawkins, CE; Tabori, U; Rood, BR; Myseros, JS; Packer, RJ; Korshunov, A; Lichter, P; Kool, M; Pfister, SM; Schueller, U; Dirks, P; Huang, A; Bouffet, E; Rutka, JT; Bader, GD; Swanton, C; Ma, Y; Moore, RA; Mungall, AJ; Majewski, J; Jones, SJM; Das, S; Malkin, D; Jabado, N; Marra, MA; Taylor, MD; - view fewer (2017) Spatial heterogeneity in medulloblastoma. Nature Genetics , 49 (5) pp. 780-788. 10.1038/ng.3838.

Munkhbaatar, E; Dietzen, M; Agrawal, D; Anton, M; Jesinghaus, M; Boxberg, M; Pfarr, N; ... Jost, PJ; + view all Munkhbaatar, E; Dietzen, M; Agrawal, D; Anton, M; Jesinghaus, M; Boxberg, M; Pfarr, N; Bidola, P; Uhrig, S; Höckendorf, U; Meinhardt, A-L; Wahida, A; Heid, I; Braren, R; Mishra, R; Warth, A; Muley, T; Poh, PSP; Wang, X; Fröhling, S; Steiger, K; Slotta-Huspenina, J; van Griensven, M; Pfeiffer, F; Lange, S; Rad, R; Spella, M; Stathopoulos, GT; Ruland, J; Bassermann, F; Weichert, W; Strasser, A; Branca, C; Heikenwalder, M; Swanton, C; McGranahan, N; Jost, PJ; - view fewer (2020) MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically. Nature Communications , 11 (1) , Article 4527. 10.1038/s41467-020-18372-1.

Naxerova, K; Reiter, JG; Brachtel, E; Lennerz, JK; van de Wetering, M; Rowan, A; Cai, T; ... Jain, RK; + view all Naxerova, K; Reiter, JG; Brachtel, E; Lennerz, JK; van de Wetering, M; Rowan, A; Cai, T; Clevers, H; Swanton, C; Nowak, MA; Elledge, SJ; Jain, RK; - view fewer (2017) Origins of lymphatic and distant metastases in human colorectal cancer. Science , 357 (6346) pp. 55-60. 10.1126/science.aai8515.

Neal, RD; Johnson, P; Clarke, CA; Hamilton, SA; Zhang, N; Kumar, H; Swanton, C; Neal, RD; Johnson, P; Clarke, CA; Hamilton, SA; Zhang, N; Kumar, H; Swanton, C; Sasieni, P; - view fewer (2022) Cell-Free DNA–Based Multi-Cancer Early Detection Test in an Asymptomatic Screening Population (NHS-Galleri): Design of a Pragmatic, Prospective Randomised Controlled Trial. Cancers , 14 (19) , Article 4818. 10.3390/cancers14194818.

Ng, Kevin W; Boumelha, Jesse; Enfield, Katey SS; Almagro, Jorge; Cha, Hongui; Pich, Oriol; Karasaki, Takahiro; ... Kassiotis, George; + view all Ng, Kevin W; Boumelha, Jesse; Enfield, Katey SS; Almagro, Jorge; Cha, Hongui; Pich, Oriol; Karasaki, Takahiro; Moore, David A; Salgado, Roberto; Sivakumar, Monica; Young, George; Molina-Arcas, Miriam; de Carné Trécesson, Sophie; Anastasiou, Panayiotis; Fendler, Annika; Au, Lewis; Shepherd, Scott TC; Martínez-Ruiz, Carlos; Puttick, Clare; Black, James RM; Watkins, Thomas BK; Kim, Hyemin; Shim, Seohee; Faulkner, Nikhil; Attig, Jan; Veeriah, Selvaraju; Magno, Neil; Ward, Sophia; Frankell, Alexander M; Al Bakir, Maise; Lim, Emilia L; Hill, Mark S; Wilson, Gareth A; Cook, Daniel E; Birkbak, Nicolai J; Behrens, Axel; Yousaf, Nadia; Popat, Sanjay; Hackshaw, Allan; TRACERx Consortium, .; CAPTURE Consortium, .; Hiley, Crispin T; Litchfield, Kevin; McGranahan, Nicholas; Jamal-Hanjani, Mariam; Larkin, James; Lee, Se-Hoon; Turajlic, Samra; Swanton, Charles; Downward, Julian; Kassiotis, George; - view fewer (2023) Antibodies against endogenous retroviruses promote lung cancer immunotherapy. Nature 10.1038/s41586-023-05771-9. (In press).

Ng, Kevin W; Faulkner, Nikhil; Finsterbusch, Katja; Wu, Mary; Harvey, Ruth; Hussain, Saira; Greco, Maria; ... Kassiotis, George; + view all Ng, Kevin W; Faulkner, Nikhil; Finsterbusch, Katja; Wu, Mary; Harvey, Ruth; Hussain, Saira; Greco, Maria; Liu, Yafei; Kjaer, Svend; Swanton, Charles; Gandhi, Sonia; Beale, Rupert; Gamblin, Steve J; Cherepanov, Peter; McCauley, John; Daniels, Rodney; Howell, Michael; Arase, Hisashi; Wack, Andreas; Bauer, David LV; Kassiotis, George; - view fewer (2022) SARS-CoV-2 S2–targeted vaccination elicits broadly neutralizing antibodies. Science Translational Medicine , 14 (655) , Article eabn3715. 10.1126/scitranslmed.abn3715.

Ng, KW; Faulkner, N; Cornish, GH; Rosa, A; Harvey, R; Hussain, S; Ulferts, R; ... Kassiotis, G; + view all Ng, KW; Faulkner, N; Cornish, GH; Rosa, A; Harvey, R; Hussain, S; Ulferts, R; Earl, C; Wrobel, AG; Benton, DJ; Roustan, C; Bolland, W; Thompson, R; Agua-Doce, A; Hobson, P; Heaney, J; Rickman, H; Paraskevopoulou, S; Houlihan, CF; Thomson, K; Sanchez, E; Shin, GY; Spyer, MJ; Joshi, D; O'Reilly, N; Walker, PA; Kjaer, S; Riddell, A; Moore, C; Jebson, BR; Wilkinson, M; Marshall, LR; Rosser, EC; Radziszewska, A; Peckham, H; Ciurtin, C; Wedderburn, LR; Beale, R; Swanton, C; Gandhi, S; Stockinger, B; McCauley, J; Gamblin, SJ; McCoy, LE; Cherepanov, P; Nastouli, E; Kassiotis, G; - view fewer (2020) Preexisting and de novo humoral immunity to SARS-CoV-2 in humans. Science , Article eabe1107. 10.1126/science.abe1107. (In press).

Noorani, Imran; Luebeck, Jens; Rowan, Andrew; Gronroos, Eva; Barbe, Vittorio; Fabian, Mark; Nicoll, James; ... Swanton, Charles; + view all Noorani, Imran; Luebeck, Jens; Rowan, Andrew; Gronroos, Eva; Barbe, Vittorio; Fabian, Mark; Nicoll, James; Boche, Delphine; Bafna, Vineet; Mischel, Paul S; Swanton, Charles; - view fewer (2024) Oncogenic extrachromosomal DNA identification using whole-genome sequencing from formalin-fixed glioblastomas. Annals of Oncology , 35 (6) pp. 570-573. 10.1016/j.annonc.2024.03.008.

Pan, Xiaoxi; AbdulJabbar, Khalid; Coelho-Lima, Jose; Grapa, Anca-Ioana; Zhang, Hanyun; Cheung, Alvin Ho Kwan; Baena, Juvenal; ... Moore, David A; + view all Pan, Xiaoxi; AbdulJabbar, Khalid; Coelho-Lima, Jose; Grapa, Anca-Ioana; Zhang, Hanyun; Cheung, Alvin Ho Kwan; Baena, Juvenal; Karasaki, Takahiro; Wilson, Claire Rachel; Sereno, Marco; Veeriah, Selvaraju; Aitken, Sarah J; Hackshaw, Allan; Nicholson, Andrew G; Jamal-Hanjani, Mariam; TRACERx Consortium; Swanton, Charles; Yuan, Yinyin; Le Quesne, John; Moore, David A; - view fewer (2024) The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma. Nature Cancer 10.1038/s43018-023-00694-w.

Pandya, Tej; Cao, Yin; Smith-Byrne, Karl; Swanton, Charles; (2025) Mechanism-Enhanced Population Science: Strengthening Population Studies Through Mechanistic Insights. Annals of Oncology 10.1016/j.annonc.2025.08.006. (In press).

Passaro, Antonio; Al Bakir, Maise; Hamilton, Emily G; Diehn, Maximilian; André, Fabrice; Roy-Chowdhuri, Sinchita; Mountzios, Giannis; ... Peters, Solange; + view all Passaro, Antonio; Al Bakir, Maise; Hamilton, Emily G; Diehn, Maximilian; André, Fabrice; Roy-Chowdhuri, Sinchita; Mountzios, Giannis; Wistuba, Ignacio I; Swanton, Charles; Peters, Solange; - view fewer (2024) Cancer biomarkers: Emerging trends and clinical implications for personalized treatment. Cell , 187 (7) pp. 1617-1635. 10.1016/j.cell.2024.02.041.

Pennycuick, A; Teixeira, VH; AbdulJabbar, K; Raza, SEA; Lund, T; Akarca, AU; Rosenthal, R; ... Janes, SM; + view all Pennycuick, A; Teixeira, VH; AbdulJabbar, K; Raza, SEA; Lund, T; Akarca, AU; Rosenthal, R; Kalinke, L; Chandrasekharan, DP; Pipinikas, CP; Lee-Six, H; Hynds, RE; Gowers, KHC; Henry, JY; Millar, FR; Hagos, YB; Denais, C; Falzon, M; Moore, DA; Antoniou, S; Durrenberger, PF; Furness, AJS; Carroll, B; Marceaux, C; Asselin-Labat, M-L; Larson, W; Betts, C; Coussens, LM; Thakrar, RM; George, J; Swanton, C; Thirlwell, C; Campbell, PJ; Marafioti, T; Yuan, Y; Quezada, SA; McGranahan, N; Janes, SM; - view fewer (2020) Immune surveillance in clinical regression of pre-invasive squamous cell lung cancer. Cancer Discovery , 10 (10) pp. 1489-1499. 10.1158/2159-8290.CD-19-1366.

Pich, Oriol; Bailey, Chris; Watkins, Thomas BK; Zaccaria, Simone; Jamal-Hanjani, Mariam; Swanton, Charles; (2022) The translational challenges of precision oncology. Cancer Cell , 40 (5) pp. 458-478. 10.1016/j.ccell.2022.04.002.

Przewrocka, J; Rowan, A; Rosenthal, R; Kanu, N; Swanton, C; (2020) Unintended on-target chromosomal instability following CRISPR/Cas9 single gene targeting. Annals of Oncology , 31 (9) pp. 1270-1273. 10.1016/j.annonc.2020.04.480.

Puttick, Clare; Jones, Thomas P; Leung, Michelle M; Galvez-Cancino, Felipe; Liu, Jiali; Varas-Godoy, Manuel; Rowan, Andrew; ... Mcgranahan, Nicholas; + view all Puttick, Clare; Jones, Thomas P; Leung, Michelle M; Galvez-Cancino, Felipe; Liu, Jiali; Varas-Godoy, Manuel; Rowan, Andrew; Pich, Oriol; Martinez-Ruiz, Carlos; Bentham, Robert; Dijkstra, Krijn K; Black, James RM; Rosenthal, Rachel; Kanu, Nnennaya; Litchfield, Kevin; Salgado, Roberto; Moore, David A; Van Loo, Peter; Jamal-Hanjani, Mariam; Quezada, Sergio A; Swanton, Charles; Mcgranahan, Nicholas; - view fewer (2024) MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution. Nature Genetics , 56 (10) pp. 2121-2131. 10.1038/s41588-024-01883-8.

Rane, Jayant K; Frankell, Alexander M; Weeden, Clare E; Swanton, Charles; (2023) Clonal Evolution in Healthy and Premalignant Tissues: Implications for Early Cancer Interception Strategies. Cancer Prevention Research , 16 (7) pp. 369-378. 10.1158/1940-6207.CAPR-22-0469.

Reading, James L; Caswell, Deborah R; Swanton, Charles; (2023) Tumor heterogeneity impairs immunogenicity in mismatch repair deficient tumors. Nature Genetics , 55 (10) pp. 1610-1612. 10.1038/s41588-023-01492-x.

Reading, JL; Gálvez-Cancino, F; Swanton, RC; Lladser, A; Peggs, K; Quezada, S; (2018) The function and dysfunction of memory CD8+ T cells in tumor immunity. Immunological Reviews , 283 (1) pp. 194-212. 10.1111/imr.12657.

Rodríguez-Martínez, M; Boissiére, T; Gonzalez, MN; Litchfield, K; Mitter, R; Walker, J; Kjœr, S; ... Svejstrup, JQ; + view all Rodríguez-Martínez, M; Boissiére, T; Gonzalez, MN; Litchfield, K; Mitter, R; Walker, J; Kjœr, S; Ismail, M; Downward, J; Swanton, C; Svejstrup, JQ; - view fewer (2020) Evidence That STK19 Is Not an NRAS-dependent Melanoma Driver. Cell , 181 (6) 1395-1405.e11. 10.1016/j.cell.2020.04.014.

Rosenthal, R; Cadieux, EL; Salgado, R; Bakir, MA; Moore, DA; Hiley, CT; Lund, T; ... TRACERx consortium; + view all Rosenthal, R; Cadieux, EL; Salgado, R; Bakir, MA; Moore, DA; Hiley, CT; Lund, T; Tanić, M; Reading, JL; Joshi, K; Henry, JY; Ghorani, E; Wilson, GA; Birkbak, NJ; Jamal-Hanjani, M; Veeriah, S; Szallasi, Z; Loi, S; Hellmann, MD; Feber, A; Chain, B; Herrero, J; Quezada, SA; Demeulemeester, J; Van Loo, P; Beck, S; McGranahan, N; Swanton, C; TRACERx consortium; - view fewer (2019) Neoantigen-directed immune escape in lung cancer evolution. Nature 10.1038/s41586-019-1032-7. (In press).

Rosenthal, R; McGranahan, N; Herrero, J; Swanton, C; (2017) Deciphering Genetic Intratumor Heterogeneity and Its Impact on Cancer Evolution. Annual Review of Cancer Biology , 1 pp. 223-240. 10.1146/annurev-cancerbio-042516-011348.

Rosenthal, R; McGranahan, N; Herrero, J; Taylor, BS; Swanton, C; (2016) deconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution. Genome Biol , 17 (1) p. 31. 10.1186/s13059-016-0893-4.

Rosenthal, R; Swanton, C; McGranahan, N; (2021) Understanding the impact of immune-mediated selection on lung cancer evolution. British Journal of Cancer , 124 (10) pp. 1615-1617. 10.1038/s41416-020-01232-6.

Sansregret, L; Patterson, JO; Dewhurst, S; Lopez-Garcia, C; Koch, A; McGranahan, N; Chao, WCH; ... Swanton, C; + view all Sansregret, L; Patterson, JO; Dewhurst, S; Lopez-Garcia, C; Koch, A; McGranahan, N; Chao, WCH; Barry, DJ; Rowan, A; Instrell, R; Horswell, S; Way, M; Howell, M; Singleton, MR; Medema, RH; Nurse, P; Petronczki, M; Swanton, C; - view fewer (2017) APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability. Cancer Discovery , 7 (2) pp. 218-233. 10.1158/2159-8290.CD-16-0645.

Sansregret, L; Swanton, C; (2017) The Role of Aneuploidy in Cancer Evolution. Cold Spring Harbor Perspectives in Medicine , 7 (1) , Article a028373. 10.1101/cshperspect.a028373.

Sansregret, L; Vanhaesebroeck, B; Swanton, C; (2018) Determinants and clinical implications of chromosomal instability in cancer. Nature Reviews Clinical Oncology , 15 (3) pp. 139-150. 10.1038/nrclinonc.2017.198.

Sasieni, P; Smittenaar, R; Hubbell, E; Broggio, J; Neal, RD; Swanton, C; (2023) Modelled mortality benefits of multi-cancer early detection screening in England. British Journal of Cancer , 129 pp. 72-80. 10.1038/s41416-023-02243-9.

Sasieni, P; Swanton, C; Neal, R; (2025) Advanced cancer: a robust surrogate of cancer mortality in early detection trials? Annals of Oncology 10.1016/j.annonc.2025.03.001. (In press).

Sasieni, Peter; Swanton, Charles; Neal, Richard D; (2025) The National Health Service-Galleri multi-cancer screening trial: explanation and justification of unique and important design issues. Journal of the National Cancer Institute , Article djaf218. 10.1093/jnci/djaf218. (In press).

Savas, Peter; Teo, Zhi Ling; Lefevre, Christophe; Flensburg, Christoffer; Caramia, Franco; Alsop, Kathryn; Mansour, Mariam; ... Loi, Sherene; + view all Savas, Peter; Teo, Zhi Ling; Lefevre, Christophe; Flensburg, Christoffer; Caramia, Franco; Alsop, Kathryn; Mansour, Mariam; Francis, Prudence A; Thorne, Heather A; Silva, Maria Joao; Kanu, Nnennaya; Dietzen, Michelle; Rowan, Andrew; Kschischo, Maik; Fox, Stephen; Bowtell, David D; Dawson, Sarah-Jane; Speed, Terence P; Swanton, Charles; Loi, Sherene; - view fewer (2017) Correction: The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE". [Corrigendum]. PLoS Med , 14 (4) e1002302. 10.1371/journal.pmed.1002302.

Savas, P; Teo, ZL; Lefevre, C; Flensburg, C; Caramia, F; Alsop, K; Mansour, M; ... Loi, S; + view all Savas, P; Teo, ZL; Lefevre, C; Flensburg, C; Caramia, F; Alsop, K; Mansour, M; Francis, PA; Thorne, HA; Silva, MJ; Kanu, N; Dietzen, M; Rowan, A; Kschischo, M; Fox, S; Bowtell, DD; Dawson, S-J; Speed, TP; Swanton, C; Loi, S; - view fewer (2016) The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE". PLoS Medicine , 13 (12) , Article e1002204. 10.1371/journal.pmed.1002204.

Scelo, G; Hofmann, JN; Banks, RE; Bigot, P; Bhatt, RS; Cancel-Tassin, G; Chew, SK; ... Chanock, SJ; + view all Scelo, G; Hofmann, JN; Banks, RE; Bigot, P; Bhatt, RS; Cancel-Tassin, G; Chew, SK; Creighton, CJ; Cussenot, O; Davis, IJ; Escudier, B; Frayling, TM; Haggstrom, C; Hildebrandt, MAT; Holcatova, I; Johansson, M; Linehan, WM; McDermott, DF; Nathanson, KL; Ogawa, S; Perlman, EJ; Purdue, MP; Stattin, P; Swanton, C; Vasudev, NS; Wu, X; Znaor, A; Brennan, P; Chanock, SJ; - view fewer (2016) International cancer seminars: a focus on kidney cancer. Annals of Oncology , 27 (8) pp. 1382-1385. 10.1093/annonc/mdw186.

Shao, SH; Allen, B; Clement, J; Chung, G; Gao, J; Hubbell, E; Liu, MC; ... Tummala, M; + view all Shao, SH; Allen, B; Clement, J; Chung, G; Gao, J; Hubbell, E; Liu, MC; Swanton, C; Tang, WW; Yimer, H; Tummala, M; - view fewer (2022) Multi-cancer early detection test sensitivity for cancers with and without current population-level screening options. Tumori 10.1177/03008916221133136. (In press).

Shawe-Taylor, Marianne; Greenwood, David; Hobbs, Agnieszka; Dowgier, Giulia; Penn, Rebecca; Sanderson, Theo; Stevenson-Leggett, Phoebe; ... Wall, Emma C; + view all Shawe-Taylor, Marianne; Greenwood, David; Hobbs, Agnieszka; Dowgier, Giulia; Penn, Rebecca; Sanderson, Theo; Stevenson-Leggett, Phoebe; Bazire, James; Harvey, Ruth; Crick COVID Serology Pipeline Investigators, Legacy Investigator; Libri, Vincenzo; Kassiotis, George; Gamblin, Steve; Lewis, Nicola S; Williams, Bryan; Swanton, Charles; Gandhi, Sonia; Carr, Edward J; Wu, Mary Y; Bauer, David LV; Wall, Emma C; - view fewer (2024) Divergent performance of vaccines in the UK autumn 2023 COVID-19 booster campaign. The Lancet , 403 (10432) pp. 1133-1136. 10.1016/S0140-6736(24)00316-7.

Spain, Lavinia; Coulton, Alexander; Lobon, Irene; Rowan, Andrew; Schnidrig, Desiree; Shepherd, Scott TC; Shum, Benjamin; ... Turajlic, Samra; + view all Spain, Lavinia; Coulton, Alexander; Lobon, Irene; Rowan, Andrew; Schnidrig, Desiree; Shepherd, Scott TC; Shum, Benjamin; Byrne, Fiona; Goicoechea, Maria; Piperni, Elisa; Au, Lewis; Edmonds, Kim; Carlyle, Eleanor; Hunter, Nikki; Renn, Alexandra; Messiou, Christina; Hughes, Peta; Nobbs, Jaime; Foijer, Floris; van den Bos, Hilda; Wardenaar, Rene; Spierings, Diana CJ; Spencer, Charlotte; Schmitt, Andreas M; Tippu, Zayd; Lingard, Karla; Grostate, Lauren; Peat, Kema; Kelly, Kayleigh; Sarker, Sarah; Vaughan, Sarah; Mangwende, Mary; Terry, Lauren; Kelly, Denise; Biano, Jennifer; Murra, Aida; Korteweg, Justine; Lewis, Charlotte; O'Flaherty, Molly; Cattin, Anne-Laure; Emmerich, Max; Gerard, Camille L; Pallikonda, Husayn Ahmed; Lynch, Joanna; Mason, Robert; Rogiers, Aljosja; Xu, Hang; Huebner, Ariana; McGranahan, Nicholas; Al Bakir, Maise; Murai, Jun; Naceur-Lombardelli, Cristina; Borg, Elaine; Mitchison, Miriam; Moore, David A; Falzon, Mary; Proctor, Ian; Stamp, Gordon WH; Nye, Emma L; Young, Kate; Furness, Andrew JS; Pickering, Lisa; Stewart, Ruby; Mahadeva, Ula; Green, Anna; Larkin, James; Litchfield, Kevin; Swanton, Charles; Jamal-Hanjani, Mariam; PEACE Consortium; Turajlic, Samra; - view fewer (2023) Late-Stage Metastatic Melanoma Emerges through a Diversity of Evolutionary Pathways. Cancer Discovery , 13 (6) pp. 1364-1385. 10.1158/2159-8290.CD-22-1427.

Sud, A; Jones, M; Broggio, J; Loveday, C; Torr, B; Garrett, A; Nicol, DL; ... Turnbull, C; + view all Sud, A; Jones, M; Broggio, J; Loveday, C; Torr, B; Garrett, A; Nicol, DL; Jhanji, S; Boyce, SA; Gronthoud, F; Ward, P; Handy, JM; Yousaf, N; Larkin, J; Suh, Y-E; Scott, S; Pharoah, PDP; Swanton, C; Abbosh, C; Williams, M; Lyratzopoulos, G; Houlston, R; Turnbull, C; - view fewer (2020) Collateral damage: the impact on outcomes from cancer surgery of the COVID-19 pandemic. Annals of Oncology 10.1016/j.annonc.2020.05.009. (In press).

Sud, A; Torr, B; Jones, ME; Broggio, J; Scott, S; Loveday, C; Garrett, A; ... Turnbull, C; + view all Sud, A; Torr, B; Jones, ME; Broggio, J; Scott, S; Loveday, C; Garrett, A; Gronthoud, F; Nicol, DL; Jhanji, S; Boyce, SA; Williams, M; Riboli, E; Muller, DC; Kipps, E; Larkin, J; Navani, N; Swanton, C; Lyratzopoulos, G; McFerran, E; Lawler, M; Houlston, R; Turnbull, C; - view fewer (2020) Effect of delays in the 2-week-wait cancer referral pathway during the COVID-19 pandemic on cancer survival in the UK: a modelling study. The Lancet Oncology , 21 (8) pp. 1035-1044. 10.1016/S1470-2045(20)30392-2.

Swanton, C; Bernard, E; Abbosh, C; André, F; Auwerx, J; Balmain, A; Bar-Sagi, D; ... Hanahan, D; + view all Swanton, C; Bernard, E; Abbosh, C; André, F; Auwerx, J; Balmain, A; Bar-Sagi, D; Bernards, R; Bullman, S; DeGregori, J; Elliott, C; Erez, A; Evan, G; Febbraio, MA; Hidalgo, A; Jamal-Hanjani, M; Joyce, JA; Kaiser, M; Lamia, K; Locasale, JW; Loi, S; Malanchi, I; Merad, M; Musgrave, K; Patel, KJ; Quezada, S; Wargo, JA; Weeraratna, A; White, E; Winkler, F; Wood, JN; Vousden, KH; Hanahan, D; - view fewer (2024) Embracing cancer complexity: Hallmarks of systemic disease. Cell , 187 (7) pp. 1589-1616. 10.1016/j.cell.2024.02.009.

Swanton, C; Beck, SA; (2014) Epigenetic noise fuels cancer evolution. Cancer Cell , 26 (6) pp. 775-776. 10.1016/j.ccell.2014.11.003.

Swanton, C; Govindan, R; (2016) Clinical Implications of Genomic Discoveries in Lung Cancer. New England Journal of Medicine , 374 (19) pp. 1864-1873. 10.1056/NEJMra1504688.

Sweeney, Christopher J; Hainsworth, John D; Bose, Ron; Burris, Howard A; Kurzrock, Razelle; Swanton, Charles; Friedman, Claire F; ... Meric-Bernstam, Funda; + view all Sweeney, Christopher J; Hainsworth, John D; Bose, Ron; Burris, Howard A; Kurzrock, Razelle; Swanton, Charles; Friedman, Claire F; Spigel, David R; Szado, Tania; Schulze, Katja; Price, Richard; Malato, Julia; Lo, Amy A; Levy, Jonathan; Wang, Yong; Yu, Wei; Meric-Bernstam, Funda; - view fewer (2024) MyPathway Human Epidermal Growth Factor Receptor 2 Basket Study: Pertuzumab + Trastuzumab Treatment of a Tissue-Agnostic Cohort of Patients With Human Epidermal Growth Factor Receptor 2–Altered Advanced Solid Tumors. Journal of Clinical Oncology , 42 (3) pp. 258-265. 10.1200/JCO.22.02636.

Szikriszt, B; Póti, Á; Németh, E; Kanu, N; Swanton, C; Szüts, D; (2021) A comparative analysis of the mutagenicity of platinum-containing chemotherapeutic agents reveals direct and indirect mutagenic mechanisms. Mutagenesis , 36 (1) pp. 75-86. 10.1093/mutage/geab005.

Szikriszt, B; Poti, A; Pipek, O; Krzystanek, M; Kanu, N; Molnar, J; Ribli, D; ... Szuts, D; + view all Szikriszt, B; Poti, A; Pipek, O; Krzystanek, M; Kanu, N; Molnar, J; Ribli, D; Szeltner, Z; Tusnady, GE; Csabai, I; Szallasi, Z; Swanton, C; Szuts, D; - view fewer (2016) A comprehensive survey of the mutagenic impact of common cancer cytotoxics. Genome Biology , 17 , Article 99. 10.1186/s13059-016-0963-7.

Tang, WHW; Yimer, H; Tummala, M; Shao, S; Chung, G; Clement, J; Chu, BC; ... Roberts, LR; + view all Tang, WHW; Yimer, H; Tummala, M; Shao, S; Chung, G; Clement, J; Chu, BC; Hubbell, E; Kurtzman, KN; Swanton, C; Roberts, LR; - view fewer (2023) Performance of a targeted methylation-based multi-cancer early detection test by race and ethnicity. Preventive Medicine , 167 , Article 107384. 10.1016/j.ypmed.2022.107384.

Teixeira, VH; Pipinikas, CP; Pennycuick, A; Lee-Six, H; Chandrasekharan, D; Beane, J; Morris, TJ; ... Janes, SM; + view all Teixeira, VH; Pipinikas, CP; Pennycuick, A; Lee-Six, H; Chandrasekharan, D; Beane, J; Morris, TJ; Karpathakis, A; Feber, A; Breeze, CE; Ntolios, P; Hynds, RE; Falzon, M; Capitanio, A; Carroll, B; Durrenberger, PF; Hardavella, G; Brown, JM; Lynch, AG; Farmery, H; Paul, DS; Chambers, RC; McGranahan, N; Navani, N; Thakrar, RM; Swanton, C; Beck, S; George, PJ; Spira, A; Campbell, PJ; Thirlwell, C; Janes, SM; - view fewer (2019) Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions. Nature Medicine , 25 pp. 517-525. 10.1038/s41591-018-0323-0.

Trebeschi, S; Drago, SG; Birkbak, NJ; Kurilova, I; Calin, AM; Pizzi, AD; Lalezari, F; ... Aerts, HJWL; + view all Trebeschi, S; Drago, SG; Birkbak, NJ; Kurilova, I; Calin, AM; Pizzi, AD; Lalezari, F; Lambregts, DMJ; Rohaan, MW; Parmar, C; Rozeman, EA; Hartemink, KJ; Swanton, C; Haanen, JBAG; Blank, CU; Smit, EF; Beets-Tan, RGH; Aerts, HJWL; - view fewer (2019) Predicting response to cancer immunotherapy using noninvasive radiomic biomarkers. Annals of Oncology , 30 (6) pp. 998-1004. 10.1093/annonc/mdz108.

Turajlic, S; Litchfield, K; Xu, H; Rosenthal, R; McGranahan, N; Reading, JL; Wong, YNS; ... Swanton, C; + view all Turajlic, S; Litchfield, K; Xu, H; Rosenthal, R; McGranahan, N; Reading, JL; Wong, YNS; Rowan, A; Kanu, N; Al Bakir, M; Chambers, T; Salgado, R; Savas, P; Loi, S; Birkbak, NJ; Sansregret, L; Gore, M; Larkin, J; Quezada, SA; Swanton, C; - view fewer (2017) Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis. The Lancet Oncology , 18 (8) pp. 1009-1021. 10.1016/S1470-2045(17)30516-8.

Turajlic, S; Swanton, C; Boshoff, C; (2018) Kidney cancer: The next decade. Journal of Experimental Medicine , 215 (9) 10.1084/jem.20181617.

Turajlic, S; Xu, H; Litchfield, K; Rowan, A; Chambers, T; Lopez, JI; Nicol, D; ... Swanton, C; + view all Turajlic, S; Xu, H; Litchfield, K; Rowan, A; Chambers, T; Lopez, JI; Nicol, D; O'Brien, T; Larkin, J; Horswell, S; Stares, M; Au, L; Jamal-Hanjani, M; Challacombe, B; Chandra, A; Hazell, S; Eichler-Jonsson, C; Soultati, A; Chowdhury, S; Rudman, S; Lynch, J; Fernando, A; Stamp, G; Nye, E; Jabbar, F; Spain, L; Lall, S; Guarch, R; Falzon, M; Proctor, I; Pickering, L; Gore, M; Watkins, TBK; Ward, S; Stewart, A; DiNatale, R; Becerra, MF; Reznik, E; Hsieh, JJ; Richmond, TA; Mayhew, GF; Hill, SM; McNally, CD; Jones, C; Rosenbaum, H; Stanislaw, S; Burgess, DL; Alexander, NR; Swanton, C; - view fewer (2018) Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal. Cell , 173 (3) 581-594.e12. 10.1016/j.cell.2018.03.057.

Turajlic, S; Xu, H; Litchfield, K; Rowan, A; Horswell, S; Chambers, T; O'Brien, T; ... TRACERx Renal Consortium, .; + view all Turajlic, S; Xu, H; Litchfield, K; Rowan, A; Horswell, S; Chambers, T; O'Brien, T; Lopez, JI; Watkins, TBK; Nicol, D; Stares, M; Challacombe, B; Hazell, S; Chandra, A; Mitchell, TJ; Au, L; Eichler-Jonsson, C; Jabbar, F; Soultati, A; Chowdhury, S; Rudman, S; Lynch, J; Fernando, A; Stamp, G; Nye, E; Stewart, A; Xing, W; Smith, JC; Escudero, M; Huffman, A; Matthews, N; Elgar, G; Phillimore, B; Costa, M; Begum, S; Ward, S; Salm, M; Boeing, S; Fisher, R; Spain, L; Navas, C; Grönroos, E; Hobor, S; Sharma, S; Aurangzeb, I; Lall, S; Polson, A; Varia, M; Horsfield, C; Fotiadis, N; Pickering, L; Schwarz, RF; Silva, B; Herrero, J; Luscombe, NM; Jamal-Hanjani, M; Rosenthal, R; Birkbak, NJ; Wilson, GA; Pipek, O; Ribli, D; Krzystanek, M; Csabai, I; Szallasi, Z; Gore, M; McGranahan, N; Van Loo, P; Campbell, P; Larkin, J; Swanton, C; TRACERx Renal Consortium, .; - view fewer (2018) Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal. Cell , 173 (3) 595-610.e11. 10.1016/j.cell.2018.03.043.

Uddin, I; Joshi, K; Oakes, T; Heather, JM; Swanton, C; TRACERx consortium, .; Chain, B; (2019) An Economical, Quantitative, and Robust Protocol for High-Throughput T Cell Receptor Sequencing from Tumor or Blood. Cancer Immunosurveillance: Methods and Protocols pp. 15-42. 10.1007/978-1-4939-8885-3_2.

Usaite, Ieva; Biswas, Dhruva; Dijkstra, Krijn; Watkins, Thomas Bk; Pich, Oriol; Puttick, Clare; Angelova, Mihaela; ... Kanu, Nnennaya; + view all Usaite, Ieva; Biswas, Dhruva; Dijkstra, Krijn; Watkins, Thomas Bk; Pich, Oriol; Puttick, Clare; Angelova, Mihaela; Thakkar, Krupa; Hiley, Crispin; Birkbak, Nicolai; Kok, Marleen; Zaccaria, Simone; Wu, Yin; Litchfield, Kevin; Swanton, Charles; Kanu, Nnennaya; - view fewer (2023) Quantifying the impact of immunotherapy on RNA dynamics in cancer. Journal for ImmunoTherapy of Cancer , 11 (11) , Article e007870. 10.1136/jitc-2023-007870.

van Maldegem, F; Valand, K; Cole, M; Patel, H; Angelova, M; Rana, S; Colliver, E; ... Downward, J; + view all van Maldegem, F; Valand, K; Cole, M; Patel, H; Angelova, M; Rana, S; Colliver, E; Enfield, K; Bah, N; Kelly, G; Tsang, VSK; Mugarza, E; Moore, C; Hobson, P; Levi, D; Molina-Arcas, M; Swanton, C; Downward, J; - view fewer (2021) Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry. Nature Communications , 12 (1) , Article 5906. 10.1038/s41467-021-26214-x.

Vargas, FA; Furness, AJS; Litchfield, K; Joshi, K; Rosenthal, R; Ghorani, E; Solomon, I; ... Quezada, SA; + view all Vargas, FA; Furness, AJS; Litchfield, K; Joshi, K; Rosenthal, R; Ghorani, E; Solomon, I; Lesko, MH; Ruef, N; Roddie, C; Henry, JY; Spain, L; Ben Aissa, A; Georgiou, A; Wong, YNS; Smith, M; Strauss, D; Hayes, A; Nicol, D; O'Brien, T; Martensson, L; Ljungars, A; Teige, I; Frendeus, B; Pule, M; Marafioti, T; Gore, M; Larkin, J; Turajlic, S; Swanton, C; Peggs, KS; Quezada, SA; - view fewer (2018) Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies. Cancer Cell , 33 (4) pp. 649-663. 10.1016/j.ccell.2018.02.010.

Vargas, FA; Furness, AJS; Solomon, I; Joshi, K; Mekkaoui, L; Lesko, MH; Rota, EM; ... Quezada, SA; + view all Vargas, FA; Furness, AJS; Solomon, I; Joshi, K; Mekkaoui, L; Lesko, MH; Rota, EM; Dahan, R; Georgiou, A; Sledzinska, A; Ben Aissa, A; Franz, D; Sunderland, MW; Wong, YNS; Henry, JY; O'Brien, T; Nicol, D; Challacombe, B; Beers, SA; Turajlic, S; Gore, M; Larkin, J; Swanton, C; Chester, KA; Pule, M; Ravetch, JV; Marafioti, T; Peggs, KS; Quezada, SA; - view fewer (2017) Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors. Immunity , 46 (4) pp. 577-586. 10.1016/j.immuni.2017.03.013.

Vendramin, R; Litchfield, K; Swanton, C; (2021) Cancer evolution: Darwin and beyond. EMBO Journal , Article e108389. 10.15252/embj.2021108389.

Venkatesan, S; Angelova, M; Bartkova, J; Bakhoum, SF; Bartek, J; Kanu, N; Swanton, C; (2021) APOBEC3 as a driver of genetic intratumor heterogeneity. Molecular and Cellular Oncology 10.1080/23723556.2021.2014734. (In press).

Venkatesan, S; Angelova, M; Puttick, C; Zhai, H; Caswell, DR; Lu, W-T; Dietzen, M; ... Consortium, T; + view all Venkatesan, S; Angelova, M; Puttick, C; Zhai, H; Caswell, DR; Lu, W-T; Dietzen, M; Galanos, P; Evangelou, K; Bellelli, R; Lim, EL; Watkins, TBK; Rowan, A; Teixeira, VH; Zhao, Y; Chen, H; Ngo, B; Zalmas, L-P; Al Bakir, M; Hobor, S; Gronroos, E; Pennycuick, A; Nigro, E; Campbell, BB; Brown, WL; Akarca, AU; Marafioti, T; Wu, MY; Howell, M; Boulton, SJ; Bertoli, C; Fenton, TR; De Bruin, RAM; Maya-Mendoza, A; Santoni-Rugiu, E; Hynds, RE; Gorgoulis, VG; Jamal-Hanjani, M; McGranahan, N; Harris, RS; Janes, SM; Bartkova, J; Bakhoum, SF; Bartek, J; Kanu, N; Swanton, C; Consortium, T; - view fewer (2021) Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution. Cancer Discovery , 11 (10) pp. 2456-2473. 10.1158/2159-8290.CD-20-0725.

Venkatesan, S; Rosenthal, R; Kanu, N; McGranahan, N; Bartek, J; Quezada, SA; Hare, J; ... Swanton, C; + view all Venkatesan, S; Rosenthal, R; Kanu, N; McGranahan, N; Bartek, J; Quezada, SA; Hare, J; Harris, RS; Swanton, C; - view fewer (2018) APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution. Annals of Oncology , 29 (3) pp. 563-572. 10.1093/annonc/mdy003.

Virassamy, B; Caramia, F; Savas, P; Sant, S; Wang, J; Christo, SN; Byrne, A; ... Loi, S; + view all Virassamy, B; Caramia, F; Savas, P; Sant, S; Wang, J; Christo, SN; Byrne, A; Clarke, K; Brown, E; Teo, ZL; von Scheidt, B; Freestone, D; Gandolfo, LC; Weber, K; Teply-Szymanski, J; Li, R; Luen, SJ; Denkert, C; Loibl, S; Lucas, O; Swanton, C; Speed, TP; Darcy, PK; Neeson, PJ; Mackay, LK; Loi, S; - view fewer (2023) Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer. Cancer Cell , 41 (3) 585-601.e8. 10.1016/j.ccell.2023.01.004.

Wall, EC; Wu, M; Harvey, R; Kelly, G; Warchal, S; Sawyer, C; Daniels, R; ... Bauer, DL; + view all Wall, EC; Wu, M; Harvey, R; Kelly, G; Warchal, S; Sawyer, C; Daniels, R; Adams, L; Hobson, P; Hatipoglu, E; Ngai, Y; Hussain, S; Ambrose, K; Hindmarsh, S; Beale, R; Riddell, A; Gamblin, S; Howell, M; Kassiotis, G; Libri, V; Williams, B; Swanton, C; Gandhi, S; Bauer, DL; - view fewer (2021) AZD1222-induced neutralising antibody activity against SARS-CoV-2 Delta VOC. The Lancet 10.1016/S0140-6736(21)01462-8. (In press).

Wall, EC; Wu, M; Harvey, R; Kelly, G; Warchal, S; Sawyer, C; Daniels, R; ... Bauer, DLV; + view all Wall, EC; Wu, M; Harvey, R; Kelly, G; Warchal, S; Sawyer, C; Daniels, R; Hobson, P; Hatipoglu, E; Ngai, Y; Hussain, S; Nicod, J; Goldstone, R; Ambrose, K; Hindmarsh, S; Beale, R; Riddell, A; Gamblin, S; Howell, M; Kassiotis, G; Libri, V; Williams, B; Swanton, C; Gandhi, S; Bauer, DLV; - view fewer (2021) Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination. The Lancet 10.1016/s0140-6736(21)01290-3. (In press).

Watkins, Thomas BK; Colliver, Emma C; Huska, Matthew R; Kaufmann, Tom L; Lim, Emilia L; Duncan, Cody B; Haase, Kerstin; ... Schwarz, Roland F; + view all Watkins, Thomas BK; Colliver, Emma C; Huska, Matthew R; Kaufmann, Tom L; Lim, Emilia L; Duncan, Cody B; Haase, Kerstin; Van Loo, Peter; Swanton, Charles; McGranahan, Nicholas; Schwarz, Roland F; - view fewer (2023) Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity. PLoS Computational Biology , 19 (10) , Article e1011379. 10.1371/journal.pcbi.1011379.

Watkins, TBK; Lim, EL; Petkovic, M; Elizalde, S; Birkbak, NJ; Wilson, GA; Moore, DA; ... Swanton, C; + view all Watkins, TBK; Lim, EL; Petkovic, M; Elizalde, S; Birkbak, NJ; Wilson, GA; Moore, DA; Grönroos, E; Rowan, A; Dewhurst, SM; Demeulemeester, J; Dentro, SC; Horswell, S; Au, L; Haase, K; Escudero, M; Rosenthal, R; Bakir, MA; Xu, H; Litchfield, K; Lu, WT; Mourikis, TP; Dietzen, M; Spain, L; Cresswell, GD; Biswas, D; Lamy, P; Nordentoft, I; Harbst, K; Castro-Giner, F; Yates, LR; Caramia, F; Jaulin, F; Vicier, C; Tomlinson, IPM; Brastianos, PK; Cho, RJ; Bastian, BC; Dyrskjøt, L; Jönsson, GB; Savas, P; Loi, S; Campbell, PJ; Andre, F; Luscombe, NM; Steeghs, N; Tjan-Heijnen, VCG; Szallasi, Z; Turajlic, S; Jamal-Hanjani, M; Van Loo, P; Bakhoum, SF; Schwarz, RF; McGranahan, N; Swanton, C; - view fewer (2020) Pervasive chromosomal instability and karyotype order in tumour evolution. Nature , 587 pp. 126-132. 10.1038/s41586-020-2698-6.

Weeden, CE; Gayevskiy, V; Marceaux, C; Batey, D; Tan, T; Yokote, K; Ribera, NT; ... Asselin-Labat, ML; + view all Weeden, CE; Gayevskiy, V; Marceaux, C; Batey, D; Tan, T; Yokote, K; Ribera, NT; Clatch, A; Christo, S; Teh, CE; Mitchell, AJ; Trussart, M; Rankin, L; Obers, A; McDonald, JA; Sutherland, KD; Sharma, VJ; Starkey, G; D'Costa, R; Antippa, P; Leong, T; Steinfort, D; Irving, L; Swanton, C; Gordon, CL; Mackay, LK; Speed, TP; Gray, DHD; Asselin-Labat, ML; - view fewer (2023) Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer. Cancer Cell , 41 (5) 837-852.e6. 10.1016/j.ccell.2023.03.019.

Wolf, Y; Bartok, O; Patkar, S; Bar Eli, G; Cohen, S; Litchfield, K; Levy, R; ... Samuels, Y; + view all Wolf, Y; Bartok, O; Patkar, S; Bar Eli, G; Cohen, S; Litchfield, K; Levy, R; Jimenez-Sanchez, A; Trabish, S; Lee, JS; Karathia, H; Barnea, E; Day, C-P; Cinnamon, E; Stein, I; Solomon, A; Bitton, L; Perez-Guijarro, E; Dubovik, T; Shen-Orr, SS; Miller, ML; Merlino, G; Levin, Y; Pikarsky, E; Eisenbach, L; Admon, A; Swanton, C; Ruppin, E; Samuels, Y; - view fewer (2019) UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma. Cell , 179 (1) 219-235.e21. 10.1016/j.cell.2019.08.032.

Wong, YNS; Joshi, K; Khetrapal, P; Ismail, M; Reading, JL; Sunderland, MW; Georgiou, A; ... Quezada, SA; + view all Wong, YNS; Joshi, K; Khetrapal, P; Ismail, M; Reading, JL; Sunderland, MW; Georgiou, A; Furness, AJS; Ben Aissa, A; Ghorani, E; Oakes, T; Uddin, I; Tan, WS; Feber, A; McGovern, U; Swanton, C; Freeman, A; Marafioti, T; Briggs, TP; Kelly, JD; Powles, T; Peggs, KS; Chain, BM; Linch, MD; Quezada, SA; - view fewer (2018) Urine-derived lymphocytes as a non-invasive measure of the bladder tumor immune microenvironment. Journal of Experimental Medicine , 215 (11) pp. 2748-2759. 10.1084/jem.20181003.

Wong, YNS; Joshi, K; Pule, M; Peggs, KS; Swanton, C; Quezada, SA; Linch, M; (2017) Evolving adoptive cellular therapies in urological malignancies. Lancet Oncology , 18 (6) E341-E353. 10.1016/S1470-2045(17)30327-3.

Woodcock, HV; Eley, JD; Guillotin, D; Plate, M; Nanthakumar, CB; Martufi, M; Peace, S; ... Chambers, RC; + view all Woodcock, HV; Eley, JD; Guillotin, D; Plate, M; Nanthakumar, CB; Martufi, M; Peace, S; Joberty, G; Poeckel, D; Good, RB; Taylor, AR; Zinn, N; Redding, M; Forty, EJ; Hynds, RE; Swanton, C; Karsdal, M; Maher, TM; Bergamini, G; Marshall, RP; Blanchard, AD; Mercer, PF; Chambers, RC; - view fewer (2019) The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis. Nature Communications , 10 , Article 6. 10.1038/s41467-018-07858-8.

Woodcock, HV; Eley, JD; Guillotin, D; Platé, M; Nanthakumar, CB; Martufi, M; Peace, S; ... Chambers, RC; + view all Woodcock, HV; Eley, JD; Guillotin, D; Platé, M; Nanthakumar, CB; Martufi, M; Peace, S; Joberty, G; Poeckel, D; Good, RB; Taylor, AR; Zinn, N; Redding, M; Forty, EJ; Hynds, RE; Swanton, C; Karsdal, M; Maher, TM; Fisher, A; Bergamini, G; Marshall, RP; Blanchard, AD; Mercer, PF; Chambers, RC; - view fewer (2020) Author Correction: The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis. [Corrigendum]. Nature Communications , 11 , Article 4680. 10.1038/s41467-020-18621-3.

Wu, Mary Y; Carr, Edward J; Harvey, Ruth; Mears, Harriet V; Kjaer, Svend; Townsley, Hermaleigh; Hobbs, Agnieszka; ... Bauer, David LV; + view all Wu, Mary Y; Carr, Edward J; Harvey, Ruth; Mears, Harriet V; Kjaer, Svend; Townsley, Hermaleigh; Hobbs, Agnieszka; Ragno, Martina; Herman, Lou S; Adams, Lorin; Gamblin, Steve; Howell, Michael; Beale, Rupert; Brown, Michael; Williams, Bryan; Gandhi, Sonia; Swanton, Charles; Wall, Emma C; Bauer, David LV; - view fewer (2022) WHO's Therapeutics and COVID-19 Living Guideline on mAbs needs to be reassessed. The Lancet , 400 (10369) pp. 2193-2196. 10.1016/s0140-6736(22)01938-9.

Wu, MY; Shepherd, STC; Fendler, A; Carr, EJ; Au, L; Harvey, R; Dowgier, G; ... Turajlic, S; + view all Wu, MY; Shepherd, STC; Fendler, A; Carr, EJ; Au, L; Harvey, R; Dowgier, G; Hobbs, A; Herman, LS; Ragno, M; Adams, L; Schmitt, AM; Tippu, Z; Shum, B; Farag, S; Rogiers, A; O'Reilly, N; Bawumia, P; Smith, C; Carlyle, E; Edmonds, K; Del Rosario, L; Lingard, K; Mangwende, M; Holt, L; Ahmod, H; Korteweg, J; Foley, T; Barber, T; Hepworth, S; Emslie-Henry, A; Caulfield-Lynch, N; Byrne, F; Deng, D; Williams, B; Brown, M; Caidan, S; Gavrielides, M; MacRae, JI; Kelly, G; Peat, K; Kelly, D; Murra, A; Kelly, K; O'Flaherty, M; Popat, S; Yousaf, N; Jhanji, S; Tatham, K; Cunningham, D; Van As, N; Young, K; Furness, AJS; Pickering, L; Beale, R; Swanton, C; Gandhi, S; Gamblin, S; Bauer, DLV; Kassiotis, G; Howell, M; Walker, S; Nicholson, E; Larkin, J; Wall, EC; Turajlic, S; - view fewer (2023) Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer. Cancer Cell , 41 (5) pp. 821-823. 10.1016/j.ccell.2023.04.005.

Wu, Yin; Biswas, Dhruva; Usaite, Ieva; Angelova, Mihaela; Boeing, Stefan; Karasaki, Takahiro; Veeriah, Selvaraju; ... Swanton, Charles; + view all Wu, Yin; Biswas, Dhruva; Usaite, Ieva; Angelova, Mihaela; Boeing, Stefan; Karasaki, Takahiro; Veeriah, Selvaraju; Czyzewska-Khan, Justyna; Morton, Cienne; Joseph, Magdalene; Hessey, Sonya; Reading, James; Georgiou, Andrew; Al-Bakir, Maise; TRACERx Consortium; McGranahan, Nicholas; Jamal-Hanjani, Mariam; Hackshaw, Allan; Quezada, Sergio A; Hayday, Adrian C; Swanton, Charles; - view fewer (2022) A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer. Nature Cancer , 3 pp. 696-709. 10.1038/s43018-022-00376-z.

Wu, Y; Biswas, D; Swanton, C; (2021) Impact of cancer evolution on immune surveillance and checkpoint inhibitor response. Seminars in Cancer Biology 10.1016/j.semcancer.2021.02.013. (In press).

Yousefi, Maryam; Boross, Gábor; Weiss, Carly; Murray, Christopher W; Hebert, Jess D; Cai, Hongchen; Ashkin, Emily L; ... Winslow, Monte M; + view all Yousefi, Maryam; Boross, Gábor; Weiss, Carly; Murray, Christopher W; Hebert, Jess D; Cai, Hongchen; Ashkin, Emily L; Karmakar, Saswati; Andrejka, Laura; Chen, Leo; Wang, Minwei; Tsai, Min K; Lin, Wen-Yang; Li, Chuan; Yakhchalian, Pegah; Colón, Caterina I; Chew, Su-Kit; Chu, Pauline; Swanton, Charles; Kunder, Christian A; Petrov, Dmitri A; Winslow, Monte M; - view fewer (2022) Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities. Cancer Research , 82 (8) pp. 1589-1602. 10.1158/0008-5472.CAN-22-0059.

Zamborszky, J; Szikriszt, B; Gervai, JZ; Pipek, O; Poti, A; Krzystanek, M; Ribli, D; ... Szuets, D; + view all Zamborszky, J; Szikriszt, B; Gervai, JZ; Pipek, O; Poti, A; Krzystanek, M; Ribli, D; Szalai-Gindl, JM; Csabai, I; Szallasi, Z; Swanton, C; Richardson, AL; Szuets, D; - view fewer (2016) Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions. Oncogene , 36 (6) pp. 746-755. 10.1038/onc.2016.243.

Zhang, Hanyun; AbdulJabbar, Khalid; Moore, David A; Akarca, Ayse; Enfield, Katey SS; Jamal-Hanjani, Mariam; Raza, Shan E Ahmed; ... Yuan, Yinyin; + view all Zhang, Hanyun; AbdulJabbar, Khalid; Moore, David A; Akarca, Ayse; Enfield, Katey SS; Jamal-Hanjani, Mariam; Raza, Shan E Ahmed; Veeriah, Selvaraju; Salgado, Roberto; McGranahan, Nicholas; Le Quesne, John; Swanton, Charles; Marafioti, Teresa; Yuan, Yinyin; - view fewer (2023) Spatial Positioning of Immune Hotspots Reflects the Interplay between B and T Cells in Lung Squamous Cell Carcinoma. Cancer Research , 83 (9) pp. 1410-1425. 10.1158/0008-5472.CAN-22-2589.

Zhang, M; Luo, J-L; Sun, Q; Harber, J; Dawson, AG; Nakas, A; Busacca, S; ... Fennell, DA; + view all Zhang, M; Luo, J-L; Sun, Q; Harber, J; Dawson, AG; Nakas, A; Busacca, S; Sharkey, AJ; Waller, D; Sheaff, MT; Richards, C; Wells-Jordan, P; Gaba, A; Poile, C; Baitei, EY; Bzura, A; Dzialo, J; Jama, M; Le Quesne, J; Bajaj, A; Martison, L; Shaw, JA; Pritchard, C; Kamata, T; Kuse, N; Brannan, L; De Philip Zhang, P; Yang, H; Griffiths, G; Wilson, G; Swanton, C; Dudbridge, F; Hollox, EJ; Fennell, DA; - view fewer (2021) Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment. Nature Communications , 12 (1) , Article 1751. 10.1038/s41467-021-21798-w.

Zhao, Y; Fu, X; Lopez, JI; Rowan, A; Au, L; Fendler, A; Hazell, S; ... Litchfield, K; + view all Zhao, Y; Fu, X; Lopez, JI; Rowan, A; Au, L; Fendler, A; Hazell, S; Xu, H; Horswell, S; Shepherd, STC; Spain, L; Byrne, F; Stamp, G; O'Brien, T; Nicol, D; Augustine, M; Chandra, A; Rudman, S; Toncheva, A; Pickering, L; Sahai, E; Larkin, J; Bates, PA; Swanton, C; Turajlic, S; Challacombe, B; Chowdhury, S; Drake, W; Fernando, A; Fotiadis, N; Furness, A; Hatipoglu, E; Harrison-Phipps, K; Hill, P; Horsfield, C; Marafioti, T; Olsburgh, J; Polson, A; Quezada, S; Varia, M; Verma, H; Litchfield, K; - view fewer (2021) Selection of metastasis competent subclones in the tumour interior. Nature Ecology & Evolution , 5 pp. 1033-1045. 10.1038/s41559-021-01456-6.

Proceedings paper

Raza, SEA; AbdulJabbar, K; Jamal-Hanjani, M; Veeriah, S; Le Quesne, J; Swanton, C; Yuan, Y; (2019) Deconvolving Convolutional Neural Network for Cell Detection. In: 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019). (pp. pp. 891-894). IEEE: Venice, Italy,.

Working / discussion paper

Fendler, Annika; Au, Lewis; Shepherd, Scott TC; Byrne, Fiona; Cerrone, Maddalena; Boos, Laura Amanda; Rzeniewicz, Karolina; ... Turajlic, Samra; + view all Fendler, Annika; Au, Lewis; Shepherd, Scott TC; Byrne, Fiona; Cerrone, Maddalena; Boos, Laura Amanda; Rzeniewicz, Karolina; Gordon, William; Shum, Benjamin; Gerard, Camille L; Ward, Barry; Xie, Wenyi; Schmitt, Andreas M; Joharatnam-Hogan, Nalinie; Cornish, Georgina H; Pule, Martin; Mekkaoui, Leila; Ng, Kevin W; Carlyle, Eleanor; Edmonds, Kim; Del Rosario, Lyra; Sarker, Sarah; Lingard, Karla; Mangwende, Mary; Holt, Lucy; Ahmod, Hamid; Stone, Richard; Gomes, Camila; Flynn, Helen R; Agua-Doce, Ana; Hobson, Philip; Caidan, Simon; Howell, Michael; Wu, Mary; Goldstone, Robert; Crawford, Margaret; Cubitt, Laura; Patel, Harshil; Gavrielides, Mike; Nye, Emma; Snijders, Ambrosius P; MacRae, James; Nicod, Jerome; Gronthoud, Firza; Shea, Robyn L; Messiou, Christina; Cunningham, David; Chau, Ian; Starling, Naureen; Turner, Nicholas; Welsh, Liam; van As, Nicholas; Jones, Robin L; Droney, Joanne; Banerjee, Susana; Tatham, Kate C; Jhanji, Shaman; O'Brien, Mary; Curtis, Olivia; Harrington, Kevin; Bhide, Shreerang; Bazin, Jessica; Robinson, Anna; Stephenson, Clemency; Slattery, Tim; Khan, Yasir; Tippu, Zayd; Leslie, Isla; Gennatas, Spyridon; Okines, Alicia; Reid, Alison; Young, Kate; Furness, Andrew JS; Pickering, Lisa; Gandhi, Sonia; Gamblin, Steve; Swanton, Charles; Nicholson, Emma; Kumar, Sacheen; Yousaf, Nadia; Wilkinson, Katalin A; Swerdlow, Anthony; Harvey, Ruth; Kassiotis, George; Larkin, James; Wilkinson, Robert J; Turajlic, Samra; - view fewer (2021) Functional antibody and T-cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study. Research Square: Durham, NC, USA.

Thesis

Crockford, AJ; (2016) Deciphering tetraploid tolerance. Doctoral thesis , UCL (University College London).

Dewhurst, SM; (2015) Whole genome doubling propagates chromosomal instability and accelerates cancer genome evolution. Doctoral thesis , UCL (University College London).

This list was generated on Sun Nov 2 04:59:24 2025 GMT.