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Cancer Screening, Surrogates of Survival, and the Soma

DeGregori, James; Pharoah, Paul; Sasieni, Peter; Swanton, Charles; (2020) Cancer Screening, Surrogates of Survival, and the Soma. Cancer Cell , 38 (4) pp. 433-437. 10.1016/j.ccell.2020.09.003. Green open access

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Abstract

Screening leads to meaningful reductions in deaths from cancers. However, reductions in all-cause mortality (ACM) are harder to demonstrate. Failure to demonstrate ACM benefit should not diminish advances in cancer screening. We consider how co-morbidities related to an aging and damaged soma can hinder achievement of ACM benefit.

Type: Article
Title: Cancer Screening, Surrogates of Survival, and the Soma
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.ccell.2020.09.003
Publisher version: https://doi.org/10.1016/j.ccell.2020.09.003
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Life Sciences & Biomedicine, Oncology, Cell Biology, MORTALITY, DISEASE, RISK
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Oncology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
URI: https://discovery.ucl.ac.uk/id/eprint/10150762
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