Browse by UCL Department: listings for include files
- UCL (195324)
- UCL (195324)
- Provost and Vice Provost Offices (194099)
- School of Life and Medical Sciences (95322)
- Faculty of Brain Sciences (35349)
- UCL Institute of Prion Diseases (409)
- MRC Prion Unit at UCL (333)
- UCL Institute of Prion Diseases (409)
- Faculty of Brain Sciences (35349)
- School of Life and Medical Sciences (95322)
- Provost and Vice Provost Offices (194099)
- UCL (195324)
Jump to: Article | Book chapter | Proceedings paper | Working / discussion paper | Conference item | Thesis
Number of items at this level: 408.
Article
Akhtar, S;
Grizenkova, J;
Wenborn, A;
Hummerich, H;
Fernandez de Marco, M;
Brandner, S;
Collinge, J;
(2013)
Sod1 deficiency reduces incubation time in mouse models of prion disease.
PLoS One
, 8
(1)
, Article e54454. 10.1371/journal.pone.0054454.
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Akhtar, S;
Wenborn, A;
Brandner, S;
Collinge, J;
Lloyd, SE;
(2011)
Sex effects in mouse prion disease incubation time.
PLOS One
, 6
(12)
, Article e28741. 10.1371/journal.pone.0028741.
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Ali, Zeinab;
Godoy-Corchuelo, Juan M;
Martins-Bach, Aurea B;
Garcia-Toledo, Irene;
Fernández-Beltrán, Luis C;
Nair, Remya R;
Spring, Shoshana;
... Corrochano, Silvia; + view all
(2023)
Mutation in the FUS nuclear localisation signal domain causes neurodevelopmental and systemic metabolic alterations.
Disease Models & Mechanisms
, 16
(10)
, Article dmm050200. 10.1242/dmm.050200.
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Amaral, P;
Leonardi, T;
Han, N;
Vire, E;
Gascoigne, D;
Arias-Carrasco, R;
Buscher, M;
... Kouzarides, T; + view all
(2016)
Genomic positional conservation identifies topological anchor point (tap)RNAs linked to developmental loci.
bioRxiv
10.1101/051052.
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Amaral, PP;
Leonardi, T;
Han, N;
Viré, E;
Gascoigne, DK;
Arias-Carrasco, R;
Büscher, M;
... Kouzarides, T; + view all
(2018)
Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci.
Genome Biology
, 19
(1)
, Article 32. 10.1186/s13059-018-1405-5.
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Andrich, K;
Hegenbart, U;
Kimmich, C;
Kedia, N;
Bergen, HR;
Schönland, S;
Wanker, E;
(2017)
Aggregation of Full-length Immunoglobulin Light Chains from Systemic Light Chain Amyloidosis (AL) Patients Is Remodeled by Epigallocatechin-3-gallate.
Journal of Biological Chemistry
, 292
(6)
pp. 2328-2344.
10.1074/jbc.M116.750323.
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Anttila, V;
Bulik-Sullivan, B;
Finucane, HK;
Walters, RK;
Bras, J;
Duncan, L;
Escott-Price, V;
... Neale, BM; + view all
(2018)
Analysis of shared heritability in common disorders of the brain.
Science
, 360
(6395)
, Article eaap8757. 10.1126/science.aap8757.
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Asante, EA;
Grimshaw, A;
Smidak, M;
Jakubcova, T;
Tomlinson, A;
Jeelani, A;
Hamdan, S;
... Collinge, J; + view all
(2015)
Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS.
PLOS Pathogens
, 11
(7)
, Article e1004953. 10.1371/journal.ppat.1004953.
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Asante, EA;
Linehan, JM;
Smidak, M;
Tomlinson, A;
Grimshaw, A;
Jeelani, A;
Jakubcova, T;
... Collinge, J; + view all
(2013)
Inherited Prion Disease A117V Is Not Simply a Proteinopathy but Produces Prions Transmissible to Transgenic Mice Expressing Homologous Prion Protein.
PLoS Pathog
, 9
(9)
, Article e1003643. 10.1371/journal.ppat.1003643.
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Asante, EA;
Linehan, JM;
Tomlinson, AD;
Jakubcova, T;
Hamdan, S;
Grimshaw, A;
Smidak, M;
... Collinge, J; + view all
(2020)
Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS.
PLOS Biology
, 18
(6)
, Article e3000725. 10.1371/journal.pbio.3000725.
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Asante, EA;
Smidak, M;
Grimshaw, A;
Houghton, R;
Tomlinson, A;
Jeelani, A;
Jakubcova, T;
... Collinge, J; + view all
(2015)
A naturally occurring variant of the human prion protein completely prevents prion disease.
Nature
, 522
pp. 478-481.
10.1038/nature14510.
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Austin, A;
Beresford, L;
Price, G;
Cunningham, T;
Kalmar, B;
Yon, M;
(2022)
Sectioning and Counting of Motor Neurons in the L3 to L6 Region of the Adult Mouse Spinal Cord.
Current Protocols
, 2
(5)
, Article e428. 10.1002/cpz1.428.
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Baker, E;
Sims, R;
Leonenko, G;
Frizzati, A;
Harwood, JC;
Grozeva, D;
GERAD/PERADES, .;
... Escott-Price, V; + view all
(2019)
Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease.
PLoS One
, 14
(7)
, Article e0218111. 10.1371/journal.pone.0218111.
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Balendra, R;
Uphill, J;
Collinson, C;
Druyeh, R;
Adamson, G;
Hummerich, H;
Zerr, I;
... Mead, S; + view all
(2016)
Variants of PLCXD3 are not associated with variant or sporadic Creutzfeldt-Jakob disease in a large international study.
BMC Medical Genetics
, 17
, Article 28. 10.1186/s12881-016-0278-2.
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Banerjee, G;
Farmer, SF;
Hyare, H;
Jaunmuktane, Z;
Mead, S;
Ryan, NS;
Schott, JM;
... Collinge, J; + view all
(2024)
Iatrogenic Alzheimer’s disease in recipients of cadaveric pituitary-derived growth hormone.
Nature Medicine
10.1038/s41591-023-02729-2.
(In press).
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Banerjee, Gargi;
Collinge, John;
Fox, Nick C;
Lashley, Tammaryn;
Mead, Simon;
Schott, Jonathan M;
Werring, David J;
(2023)
Clinical considerations in early-onset cerebral amyloid angiopathy.
Brain
10.1093/brain/awad193.
(In press).
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Banerjee, Gargi;
Samra, Kiran;
Adams, Matthew E;
Jaunmuktane, Zane;
Parry-Jones, Adrian Robert;
Grieve, Joan;
Toma, Ahmed K;
... Werring, David J; + view all
(2022)
Iatrogenic cerebral amyloid angiopathy: an emerging clinical phenomenon.
Journal of Neurology, Neurosurgery and Psychiatry
10.1136/jnnp-2022-328792.
(In press).
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Banerjee, Gargi;
Schott, Jonathan M;
Ryan, Natalie S;
(2024)
Chapter 17 - Familial cerebral amyloid disorders with prominent white matter involvement.
Handbook of Clinical Neurology
, 204
pp. 289-315.
10.1016/B978-0-323-99209-1.00010-7.
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Banerjee, Gargi;
Werring, David;
(2022)
Letter to the editor, regarding "Preceding head trauma in four cases of sporadic cerebral amyloid angiopathy - case report series" recently published by Oblak and colleagues.
Journal of Stroke and Cerebrovascular Diseases
, 31
(4)
, Article 106345. 10.1016/j.jstrokecerebrovasdis.2022.106345.
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Banerjee, G;
Adams, ME;
Jaunmuktane, Z;
Lammie, GA;
Turner, B;
Wani, M;
Sawhney, IMS;
... Werring, DJ; + view all
(2019)
Early onset cerebral amyloid angiopathy following childhood exposure to cadaveric dura.
Annals of Neurology
, 85
(2)
pp. 284-290.
10.1002/ana.25407.
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Banerjee, G;
Alvares, D;
Bowen, J;
Adams, ME;
Werring, DJ;
(2019)
Minimally symptomatic cerebral amyloid angiopathy-related inflammation: three descriptive case reports.
Journal of Neurology, Neurosurgery, and Psychiatry
, 90
(1)
pp. 113-115.
10.1136/jnnp-2017-317347.
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Banerjee, G;
Ambler, G;
Keshavan, A;
Paterson, RW;
Foiani, MS;
Toombs, J;
Heslegrave, A;
... Werring, DJ; + view all
(2020)
Cerebrospinal fluid biomarkers in cerebral amyloid angiopathy.
Journal of Alzheimer's Disease
, 74
(4)
pp. 1189-1201.
10.3233/JAD-191254.
(In press).
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Banerjee, G;
Ambler, G;
Wilson, D;
Hostettler, IC;
Shakeshaft, C;
Lunawat, S;
Cohen, H;
... CROMIS-2 collaborators, .; + view all
(2020)
Baseline factors associated with early and late death in intracerebral haemorrhage survivors.
European Journal of Neurology
, 27
(7)
pp. 1257-1263.
10.1111/ene.14238.
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Banerjee, G;
Carare, R;
Cordonnier, C;
Greenberg, SM;
Schneider, JA;
Smith, EE;
Buchem, MV;
... Werring, DJ; + view all
(2017)
The increasing impact of cerebral amyloid angiopathy: essential new insights for clinical practice.
Journal of Neurology, Neurosurgery & Psychiatry
, 88
(11)
pp. 982-994.
10.1136/jnnp-2016-314697.
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Banerjee, G;
Chan, E;
Ambler, G;
Wilson, D;
Cipolotti, L;
Shakeshaft, C;
Cohen, H;
... CROMIS‐2 Collaborators, *; + view all
(2020)
Cognitive Impairment Before Atrial Fibrillation-Related Ischemic Events: Neuroimaging and Prognostic Associations.
Journal of the American Heart Association
, 9
(1)
, Article e014537. 10.1161/JAHA.119.014537.
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Banerjee, G;
Chan, E;
Ambler, G;
Wilson, D;
Cipolotti, L;
Shakeshaft, C;
Cohen, H;
... Vahidassr, D; + view all
(2019)
Effect of small-vessel disease on cognitive trajectory after atrial fibrillation-related ischaemic stroke or TIA.
Journal of Neurology
, 266
(5)
pp. 1250-1259.
10.1007/s00415-019-09256-6.
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Banerjee, G;
Forsgard, N;
Ambler, G;
Keshavan, A;
Paterson, RW;
Foiani, MS;
Toombs, J;
... Werring, DJ; + view all
(2021)
Cerebrospinal fluid metallomics in cerebral amyloid angiopathy: an exploratory analysis.
Journal of Neurology
10.1007/s00415-021-10711-6.
(In press).
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Banerjee, G;
Jang, H;
Kim, HJ;
Kim, ST;
Kim, JS;
Lee, JH;
Im, K;
... Werring, DJ; + view all
(2018)
Total MRI Small Vessel Disease Burden Correlates with Cognitive Performance, Cortical Atrophy, and Network Measures in a Memory Clinic Population.
Journal of Alzheimer's Disease
, 63
(4)
pp. 1485-1497.
10.3233/JAD-170943.
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Banerjee, G;
Kim, HJ;
Fox, Z;
Jaeger, HR;
Wilson, D;
Charidimou, A;
Na, HK;
... Werring, DJ; + view all
(2017)
MRI-visible perivascular space location is associated with Alzheimer's disease independently of amyloid burden.
Brain
, 140
(4)
pp. 1107-1116.
10.1093/brain/awx003.
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Banerjee, G;
Sammaraiee, Y;
Werring, DJ;
(2019)
The Role of Deferiprone in Iron Chelation.
The New England Journal of Medicine
, 380
(9)
pp. 891-892.
10.1056/NEJMc1817335.
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Banerjee, G;
Stone, SP;
Werring, DJ;
(2018)
Posterior circulation ischaemic stroke.
The British Medical Journal
, 361
, Article k1185. 10.1136/bmj.k1185.
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Banerjee, G;
Summers, M;
Chan, E;
Wilson, D;
Charidimou, A;
Cipolotti, L;
Werring, DJ;
(2018)
Domain-specific characterisation of early cognitive impairment following spontaneous intracerebral haemorrhage.
Journal of the Neurological Sciences
, 391
pp. 25-30.
10.1016/j.jns.2018.05.015.
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Banerjee, G;
Werring, DJ;
(2020)
Feasibility of clinical trial recruitment for cerebral amyloid angiopathy: A specialist single centre experience.
Journal of the Neurological Sciences
, 409
, Article 116580. 10.1016/j.jns.2019.116580.
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Banerjee, G;
Wilson, D;
Ambler, G;
Hostettler, IC;
Shakeshaft, C;
Cohen, H;
Yousry, T;
... CROMIS-2 collaborators; + view all
(2020)
Longer term stroke risk in intracerebral haemorrhage survivors.
Journal of Neurology, Neurosurgery and Psychiatry
10.1136/jnnp-2020-323079.
(In press).
|
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Banerjee, G;
Wilson, D;
Ambler, G;
Osei-Bonsu Appiah, K;
Shakeshaft, C;
Lunawat, S;
Cohen, H;
... CROMIS-2 Collaborators; + view all
(2017)
Cognitive Impairment Before Intracerebral Hemorrhage Is Associated With Cerebral Amyloid Angiopathy.
Stroke
, 49
pp. 40-45.
10.1161/STROKEAHA.117.019409.
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Bellenguez, Céline;
Küçükali, Fahri;
Jansen, Iris E;
Kleineidam, Luca;
Moreno-Grau, Sonia;
Amin, Najaf;
Naj, Adam C;
... Lambert, Jean-Charles; + view all
(2022)
New insights into the genetic etiology of Alzheimer's disease and related dementias.
Nature Genetics
, 54
pp. 412-436.
10.1038/s41588-022-01024-z.
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Benilova, I;
Reilly, M;
Terry, C;
Wenborn, A;
Schmidt, C;
Marinho, AT;
Risse, E;
... Collinge, J; + view all
(2020)
Highly infectious prions are not directly neurotoxic.
Proceeding of the National Academy of Sciences of the United States of America
10.1073/pnas.2007406117.
(In press).
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Best, JG;
Ambler, G;
Wilson, D;
Lee, K-J;
Lim, J-S;
Shiozawa, M;
Koga, M;
... Werring, DJ; + view all
(2021)
Development of imaging-based risk scores for prediction of intracranial haemorrhage and ischaemic stroke in patients taking antithrombotic therapy after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies.
The Lancet Neurology
, 20
(4)
pp. 294-303.
10.1016/S1474-4422(21)00024-7.
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Best, JG;
Barbato, C;
Ambler, G;
Du, H;
Banerjee, G;
Wilson, D;
Shakeshaft, C;
... Clinical Relevance of Microbleeds in Stroke (CROMIS-2) collabora; + view all
(2020)
Association of enlarged perivascular spaces and anticoagulant-related intracranial hemorrhage.
Neurology
10.1212/WNL.0000000000010788.
(In press).
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Best, S;
Shoemark, A;
Rubbo, B;
Patel, MP;
Fassad, MR;
Dixon, M;
Rogers, AV;
... Hogg, C; + view all
(2018)
Risk factors for situs defects and congenital heart disease in primary ciliary dyskinesia.
Thorax
, 74
(2)
10.1136/thoraxjnl-2018-212104.
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Bettencourt, C;
Foti, SC;
Miki, Y;
Botia, J;
Chatterjee, A;
Warner, TT;
Revesz, T;
... Holton, JL; + view all
(2020)
White matter DNA methylation profiling reveals deregulation of HIP1, LMAN2, MOBP, and other loci in multiple system atrophy.
Acta Neuropathologica
, 139
pp. 135-156.
10.1007/s00401-019-02074-0.
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Bettencourt, C;
Piras, IS;
Foti, SC;
Talboom, J;
Miki, Y;
Lashley, T;
Balazs, R;
... Holton, JL; + view all
(2020)
Epigenomics and transcriptomics analyses of multiple system atrophy brain tissue supports a role for inflammatory processes in disease pathogenesis.
Acta Neuropathologica Communications
, 8
, Article 71. 10.1186/s40478-020-00946-1.
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Bhamra, Savroop;
Arora, Parineeta;
Manka, Szymon W;
Schmidt, Christian;
Brown, Craig;
Rayner, Melissa LD;
Klöhn, Peter-Christian;
... Jat, Parmjit S; + view all
(2023)
Prion propagation is dependent on key amino acids in Charge cluster 2 within the prion protein.
Journal of Molecular Biology
, 435
(4)
, Article 167925. 10.1016/j.jmb.2022.167925.
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Bjorkqvist, M;
Wild, EJ;
Thiele, J;
Silvestroni, A;
Andre, R;
Lahiri, N;
Raibon, E;
... Tabrizi, SJ; + view all
(2008)
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
Journal of Experimental Medicine
, 205
(8)
1869 - 1877.
10.1084/jem.20080178.
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Bocchetta, M;
Todd, EG;
Peakman, G;
Cash, DM;
Convery, RS;
Russell, LL;
Thomas, DL;
... Rohrer, JD; + view all
(2021)
Differential early subcortical involvement in genetic FTD within the GENFI cohort.
NeuroImage: Clinical
, Article 102646. 10.1016/j.nicl.2021.102646.
(In press).
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Bonham, LW;
Karch, CM;
Fan, CC;
Tan, C;
Geier, EG;
Wang, Y;
Wen, N;
... International Genomics of Alzheimer’s Project (IGAP); + view all
(2018)
CXCR4 involvement in neurodegenerative diseases.
Translational Psychiatry
, 8
(1)
, Article 73. 10.1038/s41398-017-0049-7.
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Bonham, LW;
Steele, NZR;
Karch, CM;
Broce, I;
Geier, EG;
Wen, NL;
Momeni, P;
... International FTD-Genomics Consortium (IFGC), .; + view all
(2019)
Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia.
Scientific Reports
, 9
, Article 10854. 10.1038/s41598-019-46415-1.
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Borrego-Écija, S;
Sala-Llonch, R;
van Swieten, J;
Borroni, B;
Moreno, F;
Masellis, M;
Tartaglia, C;
... Genetic FTD Initiative GENFI; + view all
(2021)
Disease-related cortical thinning in presymptomatic granulin mutation carriers.
NeuroImage: Clinical
, 29
, Article 102540. 10.1016/j.nicl.2020.102540.
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Brandt, A;
Löhers, K;
Beier, M;
Leube, B;
de Torres, C;
Mora, J;
Arora, P;
... Royer-Pokora, B; + view all
(2016)
Establishment of a Conditionally Immortalized Wilms Tumor Cell Line with a Homozygous WT1 Deletion within a Heterozygous 11p13 Deletion and UPD Limited to 11p15.
PLoS One
, 11
(5)
, Article e0155561. 10.1371/journal.pone.0155561.
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Bras, J;
Darwent, L;
Orme, T;
Hardy, J;
Guerreiro, R;
Alonso, I;
Barbot, C;
... Costa, MM; + view all
(2015)
Mutations in PNKP cause recessive ataxia with oculomotor apraxia type 4.
American Journal of Human Genetics
, 96
(3)
474 - 479.
10.1016/j.ajhg.2015.01.005.
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Bras, J;
Djaldetti, R;
Alves, AM;
Mead, S;
Darwent, L;
Lleo, A;
Luis Molinuevo, J;
... Guerreiro, R; + view all
(2016)
Exome sequencing in a consanguineous family clinically diagnosed with early-onset Alzheimer's disease identifies a homozygous CTSF mutation.
Neurobiology of Aging
, 46
236.e1-236.e6.
10.1016/j.neurobiolaging.2016.06.018.
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Bras, J;
Guerreiro, R;
Darwent, L;
Parkkinen, L;
Ansorge, O;
Escott-Price, V;
Hernandez, DG;
... Hardy, J; + view all
(2014)
Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies.
Hum Mol Genet
, 23
(23)
6139 - 6146.
10.1093/hmg/ddu334.
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Brennecke, N;
Cali, I;
Mok, TH;
Speedy, H;
Consortium, GER;
Hosszu, LLP;
Stehmann, C;
... Appleby, BS; + view all
(2021)
Characterization of Prion Disease Associated with a Two-Octapeptide Repeat Insertion.
Viruses
, 13
(9)
, Article 1794. 10.3390/v13091794.
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Broce, I;
Karch, CM;
Wen, N;
Fan, CC;
Wang, Y;
Tan, CH;
Kouri, N;
... Sugrue, LP; + view all
(2018)
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.
PLoS Medicine
, 15
(1)
, Article e1002487. 10.1371/journal.pmed.1002487.
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Brown, CA;
Schmidt, C;
Poulter, M;
Hummerich, H;
Klöhn, PC;
Jat, P;
Mead, S;
... Lloyd, SE; + view all
(2014)
In-vitro screen of prion disease susceptibility genes using the scrapie cell assay.
Hum Mol Genet
, 23
(19)
pp. 5102-5108.
10.1093/hmg/ddu233.
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C Dabin, L;
Guntoro, F;
Campbell, T;
Bélicard, T;
Smith, AR;
Smith, RG;
Raybould, R;
... Viré, E; + view all
(2020)
Altered DNA methylation profiles in blood from patients with sporadic Creutzfeldt–Jakob disease.
Acta Neuropathologica
10.1007/s00401-020-02224-9.
(In press).
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Caine, D;
Nihat, A;
Crabb, P;
Rudge, P;
Cipolotti, L;
Collinge, J;
Mead, S;
(2018)
The language disorder of prion disease is characteristic of a dynamic aphasia and is rarely an isolated clinical feature.
PLoS One
, 13
(1)
, Article e0190818. 10.1371/journal.pone.0190818.
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Caine, D;
Tinelli, RJ;
Hyare, H;
De Vita, E;
Lowe, J;
Lukic, A;
Thompson, A;
... Mead, S; + view all
(2015)
The cognitive profile of prion disease: a prospective clinical and imaging study.
Ann Clin Transl Neurol
, 2
(5)
pp. 548-558.
10.1002/acn3.195.
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Canas, LS;
Sudre, CH;
De Vita, E;
Nihat, A;
Mok, TH;
Slattery, CF;
Paterson, RW;
... Modat, M; + view all
(2019)
Prion disease diagnosis using subject-specific imaging biomarkers within a multi-kernel Gaussian process.
NeuroImage: Clinical
, Article 102051. 10.1016/j.nicl.2019.102051.
(In press).
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Cash, DM;
Bocchetta, M;
Thomas, D;
Dick, KM;
van Swieten, JC;
Borroni, B;
Galimberti, D;
... Rohrer, JD; + view all
(2017)
Patterns of grey matter atrophy in genetic frontotemporal dementia: results from the GENFI study.
Neurobiology of Aging
10.1016/j.neurobiolaging.2017.10.008.
(In press).
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Castro-Seoane, R;
Hummerich, H;
Sweeting, T;
Tattum, MH;
Linehan, JM;
Fernandez de Marco, M;
Brandner, S;
... Klöhn, PC; + view all
(2012)
Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection.
PLoS Pathogens
, 8
(2)
, Article e1002538. 10.1371/journal.ppat.1002538.
|
|
|
Cerofolini, L;
Ravera, E;
Bologna, S;
Wiglenda, T;
Böddrich, A;
Purfürst, B;
Benilova, I;
... Luchinat, C; + view all
(2020)
Mixing Aβ(1–40) and Aβ(1–42) peptides generates unique amyloid fibrils.
Chemical Communications
10.1039/d0cc02463e.
(In press).
|
|
|
Chan, E;
Sammaraiee, Y;
Banerjee, G;
Martin, AF;
Farmer, S;
Cowley, P;
Sayal, P;
... Werring, DJ; + view all
(2021)
Neuropsychological and neuroimaging characteristics of classical superficial siderosis.
Journal of Neurology
, 268
pp. 4238-4247.
10.1007/s00415-021-10548-z.
|
|
Chan, Edgar;
Bonifacio, Guendalina B;
Harrison, Corin;
Banerjee, Gargi;
Best, Jonathan G;
Sacks, Benjamin;
Harding, Nicola;
... Werring, David J; + view all
(2023)
Domain-specific neuropsychological investigation of CAA with and without intracerebral haemorrhage.
Journal of Neurology
10.1007/s00415-023-11977-8.
(In press).
|
|
Chan, AS;
Mowla, SN;
Arora, P;
Jat, PS;
(2014)
Tumour suppressors and cellular senescence.
IUBMB Life
, 66
(12)
pp. 812-822.
10.1002/iub.1335.
|
|
|
Charidimou, Andreas;
Boulouis, Gregoire;
Frosch, Matthew P;
Baron, Jean-Claude;
Pasi, Marco;
Albucher, Jean Francois;
Banerjee, Gargi;
... Greenberg, Steven M; + view all
(2022)
The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study.
The Lancet Neurology
, 21
(8)
pp. 714-725.
10.1016/S1474-4422(22)00208-3.
|
|
Chia, R;
Tattum, MH;
Jones, S;
Collinge, J;
Fisher, EMC;
Jackson, GS;
(2010)
Superoxide Dismutase 1 and tgSOD1(G93A) Mouse Spinal Cord Seed Fibrils, Suggesting a Propagative Cell Death Mechanism in Amyotrophic Lateral Sclerosis.
PLOS ONE
, 5
(5)
, Article e10627. 10.1371/journal.pone.0010627.
|
|
|
Clayton, EL;
Mancuso, R;
Nielsen, TT;
Mizielinska, S;
Holmes, H;
Powell, N;
Norona, F;
... Isaacs, AM; + view all
(2017)
Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation.
Human Molecular Genetics
, 26
(5)
pp. 873-887.
10.1093/hmg/ddx003.
|
|
Clayton, EL;
Milioto, C;
Muralidharan, B;
Norona, FE;
Edgar, JR;
Soriano, A;
Jafar-Nejad, P;
... Isaacs, AM; + view all
(2018)
Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown.
Brain
, 141
(12)
pp. 3428-3442.
10.1093/brain/awy284.
|
|
|
Clayton, EL;
Mizielinska, S;
Edgar, JR;
Nielsen, TT;
Marshall, S;
Norona, FE;
Robbins, M;
... Isaacs, AM; + view all
(2015)
Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology.
Acta Neuropathologica
, 130
(4)
pp. 511-523.
10.1007/s00401-015-1475-3.
|
|
|
Collinge, J;
Jaunmuktane, Z;
Mead, S;
Rudge, P;
Brandner, S;
(2016)
Collinge et al. reply.
[Rapid communication].
Nature
, 537
E7-E9.
10.1038/nature19087.
|
|
|
Collinge, J;
Jaunmuktane, Z;
Mead, S;
Rudge, P;
Brandner, S;
(2016)
Collinge et al. reply.
[Rapid communication].
Nature
, 535
E2-E3.
10.1038/nature18603.
|
|
|
Collinge, J;
Purro, SA;
Nicoll, A;
(2018)
Prion Protein as a Toxic Acceptor of Amyloid-β Oligomers.
Biological Psychiatry
, 83
(4)
pp. 358-368.
10.1016/j.biopsych.2017.11.020.
|
|
Convery, R;
Mead, S;
Rohrer, JD;
(2019)
Review: Clinical, genetic and neuroimaging features of frontotemporal dementia.
Neuropathology and Applied Neurobiology
, 45
(1)
pp. 6-18.
10.1111/nan.12535.
|
|
Convery, RS;
Jiao, J;
Clarke, MTM;
Moore, KM;
Koriath, CAM;
Woollacott, IOC;
Weston, PSJ;
... Rohrer, JD; + view all
(2019)
Longitudinal (¹⁸F)AV-1451 PET imaging in a patient with frontotemporal dementia due to a Q351R MAPT mutation.
Journal of Neurology, Neurosurgery & Psychiatry
10.1136/jnnp-2019-320904.
(In press).
|
|
Corbett, GT;
Wang, Z;
Hong, W;
Colom-Cadena, M;
Rose, J;
Liao, M;
Asfaw, A;
... Walsh, DM; + view all
(2019)
PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins.
Acta Neuropathologica
10.1007/s00401-019-02114-9.
(In press).
|
|
|
Corbie, Rosie;
Campbell, Tracy;
Darwent, Lee;
Rudge, Peter;
Collinge, John;
Mead, Simon;
(2022)
Estimation of the number of inherited prion disease mutation carriers in the UK.
European Journal of Human Genetics
10.1038/s41431-022-01132-8.
(In press).
|
|
Coysh, Thomas;
Mead, Simon;
(2022)
The Future of Seed Amplification Assays and Clinical Trials.
Frontiers in Aging Neuroscience
, 14
, Article 872629. 10.3389/fnagi.2022.872629.
|
|
|
Crombie, Elisa M;
Korecki, Andrea J;
Cleverley, Karen;
Adair, Bethany A;
Cunningham, Thomas J;
Lee, Weaverly Colleen;
Lengyell, Tess C;
... Simpson, Elizabeth M; + view all
(2024)
Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.
Disease Models & Mechanisms
, 17
(7)
, Article dmm050741. 10.1242/dmm.050741.
|
|
Cunningham, TJ;
Stanford, C;
(2022)
Introducing a new themed collection on emerging technologies for research models of human neuronal disorders in vivo and in vitro.
Neuronal Signaling
, 6
(3)
, Article NS20220065. 10.1042/NS20220065.
|
|
D'Castro, L;
Wenborn, A;
Gros, N;
Joiner, S;
Cronier, S;
Collinge, J;
Wadsworth, JDF;
(2010)
Isolation of Proteinase K-Sensitive Prions Using Pronase E and Phosphotungstic Acid.
PLOS ONE
, 5
(12)
, Article e15679. 10.1371/journal.pone.0015679.
|
|
|
Damato, Valentina;
Theorell, Jakob;
Al-Diwani, Adam;
Kienzler, Anne-Kathrin;
Makuch, Mateusz;
Sun, Bo;
Handel, Adam;
... Irani, Sarosh R; + view all
(2022)
Rituximab abrogates aquaporin-4-specific germinal center activity in patients with neuromyelitis optica spectrum disorders.
Proceedings of the National Academy of Sciences (PNAS)
, 119
(24)
, Article e2121804119. 10.1073/pnas.2121804119.
|
|
Darwent, L;
Carmona, S;
Lohmann, E;
Guven, G;
Kun-Rodrigues, C;
Bilgic, B;
Hanagasi, H;
... Guerreiro, R; + view all
(2017)
Mutations in TYROBP are not a common cause of dementia in a Turkish cohort.
Neurobiology of Aging
, 58
240.e1-240.e3.
10.1016/j.neurobiolaging.2017.06.019.
|
|
De Boer, Sterre CM;
Woolley, Lauren;
Mol, Merel O;
Serpente, Maria;
Reus, Lianne M;
Van Minkelen, Rick;
Van Vugt, Joke FA;
... Van der Lee, Sven J; + view all
(2022)
Letter to the editor on a paper by Kaivola et al. (2020): carriership of two copies of C9orf72 hexanucleotide repeat intermediate-length alleles is not associated with amyotrophic lateral sclerosis or frontotemporal dementia.
Acta Neuropathologica Communications
, 10
, Article 141. 10.1186/s40478-022-01438-0.
|
|
De Bruijn, SE;
Fiorentino, A;
Ottaviani, D;
Fanucchi, S;
Melo, US;
Corral-Serrano, JC;
Mulders, T;
... Hardcastle, AJ; + view all
(2020)
Structural Variants Create New Topological-Associated Domains and Ectopic Retinal Enhancer-Gene Contact in Dominant Retinitis Pigmentosa.
American Journal of Human Genetics
10.1016/j.ajhg.2020.09.002.
(In press).
|
|
|
de Rojas, I;
Moreno-Grau, S;
Tesi, N;
Grenier-Boley, B;
Andrade, V;
Jansen, IE;
Pedersen, NL;
... Ruiz, A; + view all
(2021)
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
Nature Communications
, 12
(1)
, Article 3417. 10.1038/s41467-021-22491-8.
|
|
|
De Vita, E;
Ridgway, GR;
White, MJ;
Porter, MC;
Caine, D;
Rudge, P;
Collinge, J;
... Hyare, H; + view all
(2017)
Neuroanatomical correlates of prion disease progression - a 3T longitudinal voxel-based morphometry study.
NeuroImage: Clinical
, 13
pp. 89-96.
10.1016/j.nicl.2016.10.021.
|
|
DeCordova, S;
Abdelgany, A;
Murugaiah, V;
Pathan, AA;
Nayak, A;
Walker, T;
Shastri, A;
... Kishore, U; + view all
(2019)
Secretion of functionally active complement factor H related protein 5 (FHR5) by primary tumour cells derived from Glioblastoma Multiforme patients.
Immunobiology
, 224
(5)
pp. 625-631.
10.1016/j.imbio.2019.07.006.
|
|
|
Devenney, E;
Swinn, T;
Mioshi, E;
Hornberger, M;
Dawson, KE;
Mead, S;
Rowe, JB;
(2018)
The behavioural variant frontotemporal dementia phenocopy syndrome is a distinct entity - evidence from a longitudinal study.
BMC Neurology
, 18
, Article 56. 10.1186/s12883-018-1060-1.
|
|
|
Ditamo, Y;
Dentesano, YM;
Purro, SA;
Arce, CA;
Bisig, CG;
(2016)
Post-Translational Incorporation of L-Phenylalanine into the C-Terminus of α-Tubulin as a Possible Cause of Neuronal Dysfunction.
Scientific Reports
, 6
, Article 38140. 10.1038/srep38140.
|
|
|
Dodd, Daniel O;
Mechaussier, Sabrina;
Yeyati, Patricia L;
McPhie, Fraser;
Anderson, Jacob R;
Khoo, Chen Jing;
Shoemark, Amelia;
... Mill, Pleasantine; + view all
(2024)
Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules.
Science
, 384
(6694)
, Article eadf5489. 10.1126/science.adf5489.
|
|
|
Du, H;
Wilson, D;
Ambler, G;
Banerjee, G;
Shakeshaft, C;
Cohen, H;
Yousry, T;
... Clinical Relevance of Microbleeds in Stroke (CROMIS-2) Collabora, .; + view all
(2021)
Small Vessel Disease and Ischemic Stroke Risk During Anticoagulation for Atrial Fibrillation After Cerebral Ischemia.
Stroke
, 52
(1)
pp. 91-99.
10.1161/STROKEAHA.120.029474.
|
|
Dylewski, J;
Dobrinskikh, E;
Lewis, L;
Tonsawan, P;
Miyazaki, M;
Jat, PS;
Blaine, J;
(2019)
Differential trafficking of albumin and IgG facilitated by the neonatal Fc receptor in podocytes in vitro and in vivo.
PLoS One
, 14
(2)
, Article e0209732. 10.1371/journal.pone.0209732.
|
|
|
Dylewski, JF;
Wilson, N;
Lu, S;
Jat, P;
Weiser-Evans, M;
Panzer, SE;
Blaine, J;
(2020)
Isolation, purification, and conditional immortalization of murine glomerular endothelial cells of microvascular phenotype.
MethodsX
, 7
, Article 101048. 10.1016/j.mex.2020.101048.
|
|
|
Eisenmenger, L;
Porter, MC;
Carswell, CJ;
Thompson, A;
Mead, S;
Rudge, P;
Collinge, J;
... Hyare, H; + view all
(2016)
Evolution of Diffusion-Weighted Magnetic Resonance Imaging Signal Abnormality in Sporadic Creutzfeldt-Jakob Disease, With Histopathological Correlation.
JAMA Neurology
, 73
(1)
pp. 76-84.
10.1001/jamaneurol.2015.3159.
|
|
Escott-Price, V;
Bellenguez, C;
Wang, LS;
Choi, SH;
Harold, D;
Jones, L;
Holmans, P;
... Cardiovascular Health Study (CHS); + view all
(2014)
Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.
PLoS One
, 9
(6)
, Article e94661. 10.1371/journal.pone.0094661.
|
|
|
Faller, KM;
Bras, J;
Sharpe, SJ;
Anderson, GW;
Darwent, L;
Kun-Rodrigues, C;
Alroy, J;
... Guerreiro, RJ; + view all
(2016)
The Chihuahua dog: A new animal model for neuronal ceroid lipofuscinosis CLN7 disease?
Journal of Neuroscience Research
, 94
(4)
pp. 339-347.
10.1002/jnr.23710.
|
|
Fandler-Höfler, Author S Simon;
Obergottsberger, Lena;
Ambler, Gareth;
Eppinger, Sebastian;
Wünsch, Gerit;
Kneihsl, Markus;
Seiffge, David;
... Gattringer, Thomas; + view all
(2023)
Association of Presence and Pattern of MRI Markers of Cerebral Small Vessel Disease With Recurrent Intracerebral Hemorrhage.
Neurology
10.1212/WNL.0000000000207510.
(In press).
|
|
Fandler-Höfler, Simon;
Kaushik, Kanishk;
Storti, Benedetta;
Pikija, Slaven;
Mallon, Dermot;
Ambler, Gareth;
Damavandi, Payam Tabaee;
... Werring, David J; + view all
(2025)
Clinical-radiological presentation and natural history of iatrogenic cerebral amyloid angiopathy.
Journal of Neurology, Neurosurgery and Psychiatry
10.1136/jnnp-2024-335164.
(In press).
|
|
Fassad, MR;
Shoemark, A;
le Borgne, P;
Koll, F;
Patel, M;
Dixon, M;
Hayward, J;
... Mitchison, HM; + view all
(2018)
C11orf70 Mutations Disrupting the Intraflagellar Transport-Dependent Assembly of Multiple Axonemal Dyneins Cause Primary Ciliary Dyskinesia.
The American Journal of Human Genetics
, 102
(5)
pp. 956-972.
10.1016/j.ajhg.2018.03.024.
|
|
|
Fassad, MR;
Shoemark, A;
Legendre, M;
Hirst, RA;
Koll, F;
le Borgne, P;
Louis, B;
... Mitchison, HM; + view all
(2018)
Mutations in Outer Dynein Arm Heavy Chain DNAH9 Cause Motile Cilia Defects and Situs Inversus.
The American Journal of Human Genetics
10.1016/j.ajhg.2018.10.016.
(In press).
|
|
Fassad, MR;
Shoman, WI;
Morsy, H;
Patel, MP;
Radwan, N;
Jenkins, L;
Cullup, T;
... Fasseeh, N; + view all
(2020)
Clinical and genetic spectrum in 33 Egyptian families with suspected primary ciliary dyskinesia.
Clinical Genetics
, 97
(3)
pp. 509-515.
10.1111/cge.13661.
|
|
Fernández-Borges, N;
Carlos Espinosa, J;
Marín-Moreno, A;
Aguilar-Calvo, P;
Asante, EAA;
Kitamoto, T;
Mohri, S;
... Torres, JM; + view all
(2017)
Protective Effect of Val129-PrP against Bovine Spongiform Encephalopathy but not Variant Creutzfeldt-Jakob Disease.
Emerging Infectious Diseases
, 23
(9)
pp. 1522-1530.
10.3201/eid2309.161948.
|
|
Ferrari, R;
Wang, Y;
Vandrovcova, J;
Guelfi, S;
Witeolar, A;
Karch, CM;
Schork, AJ;
... Desikan, RS; + view all
(2017)
Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases.
Journal of Neurology, Neurosurgery and Psychiatry
, 88
(2)
pp. 152-164.
10.1136/jnnp-2016-314411.
|
|
|
Field, S;
Uyttenhove, C;
Stroobant, V;
Cheou, P;
Donckers, D;
Coutelier, JP;
Simpson, PT;
... Jat, PS; + view all
(2016)
Novel highly specific anti-periostin antibodies uncover the functional importance of the fascilin 1-1 domain and highlight preferential expression of periostin in aggressive breast cancer.
International Journal of Cancer
, 138
(8)
pp. 1959-1970.
10.1002/ijc.29946.
|
 |
|
Foiani, MS;
Woollacott, IO;
Heller, C;
Bocchetta, M;
Heslegrave, A;
Dick, KM;
Russell, LL;
... Rohrer, JD; + view all
(2018)
Plasma tau is increased in frontotemporal dementia.
Journal of Neurology, Neurosurgery and Psychiatry
, 89
(8)
pp. 804-807.
10.1136/jnnp-2017-317260.
|
|
|
Ford, L;
Rudge, P;
Robinson, K;
Collinge, J;
Gorham, M;
Mead, S;
(2019)
The most problematic symptoms of prion disease - an analysis of carer experiences.
International Psychogeriatrics
, 31
(8)
pp. 1181-1190.
10.1017/S1041610218001588.
|
|
|
Franklin, HD;
Russell, LL;
Peakman, G;
Greaves, CV;
Bocchetta, M;
Nicholas, J;
Poos, J;
... Genetic FTD Initiative, GENFI, .; + view all
(2021)
The Revised Self-Monitoring Scale detects early impairment of social cognition in genetic frontotemporal dementia within the GENFI cohort.
Alzheimer's Research & Therapy
, 13
(1)
, Article 127. 10.1186/s13195-021-00865-w.
|
|
|
Franko, E;
Wehner, T;
Joly, O;
Lowe, J;
Porter, MC;
Kenny, J;
Thompson, A;
... Mead, S; + view all
(2016)
Quantitative EEG parameters correlate with the progression of human prion diseases.
Journal of Neurology, Neurosurgery & Psychiatry
, 87
(10)
pp. 1061-1067.
10.1136/jnnp-2016-313501.
|
|
Fratta, P;
Mizielinska, S;
Nicoll, AJ;
Zloh, M;
Fisher, EM;
Parkinson, G;
Isaacs, AM;
(2012)
C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes.
Scientific Reports
, 2
, Article 1016. 10.1038/srep01016.
|
    |
|
Fratta, P;
Polke, JM;
Newcombe, J;
Mizielinska, S;
Lashley, T;
Poulter, M;
Beck, J;
... Fisher, EM; + view all
(2015)
Screening a UK amyotrophic lateral sclerosis cohort provides evidence of multiple origins of the C9orf72 expansion.
Neurobiology of Aging
, 36
(1)
546.e1-546.e7.
10.1016/j.neurobiolaging.2014.07.037.
|
|
Fratta, P;
Poulter, M;
Lashley, T;
Rohrer, JD;
Polke, JM;
Beck, J;
Ryan, N;
... Mead, S; + view all
(2013)
Homozygosity for the C9orf72 GGGGCC repeat expansion in frontotemporal dementia.
Acta Neuropathologica
, 126
(3)
pp. 401-409.
10.1007/s00401-013-1147-0.
|
|
|
Freir, DB;
Nicoll, AJ;
Klyubin, I;
Panico, S;
Mc Donald, JM;
Risse, E;
Asante, EA;
... Collinge, J; + view all
(2011)
Interaction between prion protein and toxic amyloid beta assemblies can be therapeutically targeted at multiple sites.
Nature Communications
, 2
, Article 336. 10.1038/ncomms1341.
|
    |
|
French, RL;
Grese, ZR;
Aligireddy, H;
Dhavale, DD;
Reeb, AN;
Kedia, N;
Kotzbauer, PT;
... Ayala, YM; + view all
(2019)
Detection of TAR DNA-binding protein 43 (TDP-43) oligomers as initial intermediate species during aggregate formation.
Journal of Biological Chemistry
, 294
(17)
pp. 6696-6709.
10.1074/jbc.RA118.005889.
|
|
Galimberti, D;
Fumagalli, GG;
Fenoglio, C;
Cioffi, SMG;
Arighi, A;
Serpente, M;
Borroni, B;
... Genetic FTD Initiative (GENFI); + view all
(2018)
Progranulin plasma levels predict the presence of GRN mutations in asymptomatic subjects and do not correlate with brain atrophy: results from the GENFI study.
Neurobiology of Aging
, 62
245.e9-245.e12.
10.1016/j.neurobiolaging.2017.10.016.
|
|
|
Gallardo, R;
Ramakers, M;
De Smet, F;
Claes, F;
Khodaparast, L;
Khodaparast, L;
Couceiro, JR;
... Rousseau, F; + view all
(2016)
De novo design of a biologically active amyloid.
Science
, 354
(6313)
, Article aah4949. 10.1126/science.aah4949.
|
|
|
Gao, Y;
Wang, T;
Yu, X;
International FTD-Genomics Consortium (IFGC);
Zhao, H;
Zeng, P;
(2020)
Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis.
Scientific Reports
, 10
, Article 12184. 10.1038/s41598-020-68848-9.
|
|
|
Ge, YJ;
Ou, YN;
Deng, YT;
Wu, BS;
Yang, L;
Zhang, YR;
Chen, SD;
... Sorbi, S; + view all
(2023)
Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood.
Biological Psychiatry
, 93
(9)
pp. 770-779.
10.1016/j.biopsych.2022.11.002.
|
|
Ghosh, U;
Yau, W-M;
Collinge, J;
Tycko, R;
(2021)
Structural differences in amyloid-β fibrils from brains of non-demented elderly individuals and Alzheimer's disease patients.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
, 118
(45)
, Article e2111863118. 10.1073/pnas.2111863118.
|
|
Gill, ON;
Spencer, Y;
Richard-Loendt, A;
Kelly, C;
Brown, D;
Sinka, K;
Andrews, N;
... Brandner, S; + view all
(2020)
Prevalence in Britain of abnormal prion protein in human appendices before and after exposure to the cattle BSE epizootic.
Acta Neuropathologica
10.1007/s00401-020-02153-7.
(In press).
|
|
|
Gill, ON;
Spencer, Y;
Richard-Loendt, A;
Kelly, C;
Dabaghian, R;
Boyes, L;
Linehan, J;
... Brandner, S; + view all
(2013)
Prevalent abnormal prion protein in human appendixes after bovine spongiform encephalopathy epizootic: large scale survey.
BMJ
, 347
, Article f5675. 10.1136/bmj.f5675.
|
|
|
Godoy-Corchuelo, Juan M;
Ali, Zeinab;
Armas, Jose M Brito;
Martins-Bach, Aurea B;
Garcia-Toledo, Irene;
Fernandez-Beltran, Luis C;
Lopez-Carbonero, Juan I;
... Corrochano, Silvia; + view all
(2024)
Corrigendum to “TDP-43-M323K causes abnormal brain development and progressive cognitive and motor deficits associated with mislocalised and increased levels of TDP-43” [Neurobiology of disease Volume 193, April 2024, 106437].
[Corrigendum].
Neurobiology of Disease
, 202
, Article 106708. 10.1016/j.nbd.2024.106708.
|
|
|
Godoy-Corchuelo, Juan M;
Ali, Zeinab;
Brito Armas, Jose M;
Martins-Bach, Aurea B;
García-Toledo, Irene;
Fernández-Beltrán, Luis C;
López-Carbonero, Juan I;
... Corrochano, Silvia; + view all
(2024)
TDP-43-M323K causes abnormal brain development and progressive cognitive and motor deficits associated with mislocalised and increased levels of TDP-43.
Neurobiology of Disease
, 193
, Article 106437. 10.1016/j.nbd.2024.106437.
|
|
Godoy-Corchuelo, Juan Miguel;
Fernandez-Beltran, Luis C;
Ali, Zeinab;
Gil-Moreno, Maria J;
Lopez-Carbonero, Juan I;
Guerrero-Sola, Antonio;
Larrad-Sainz, Angelica;
... Corrochano, Silvia; + view all
(2022)
Lipid Metabolic Alterations in the ALS-FTD Spectrum of Disorders.
Biomedicines
, 10
(5)
, Article 1105. 10.3390/biomedicines10051105.
|
|
Grizenkova, J;
Akhtar, S;
Brandner, S;
Collinge, J;
Lloyd, SE;
(2014)
Microglial Cx3cr1 knockout reduces prion disease incubation time in mice.
BMC Neurosci
, 15
, Article 44. 10.1186/1471-2202-15-44.
|
|
|
Grizenkova, J;
Akhtar, S;
Collinge, J;
Lloyd, SE;
(2010)
The Retinoic Acid Receptor Beta (Rarb) Region of Mmu14 Is Associated with Prion Disease Incubation Time in Mouse.
PLOS ONE
, 5
(12)
, Article e15019. 10.1371/journal.pone.0015019.
|
|
|
Guerreiro, R;
Escott-Price, V;
Darwent, L;
Parkkinen, L;
Ansorge, O;
Hernandez, DG;
Nalls, MA;
... Bras, J; + view all
(2016)
Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases.
Neurobiology of Aging
, 38
214.e7-214.e10.
10.1016/j.neurobiolaging.2015.10.028.
|
|
Guerreiro, R;
Escott-Price, V;
Hernandez, DG;
Kun-Rodrigues, C;
Ross, OA;
Orme, T;
Neto, JL;
... Bras, J; + view all
(2019)
Heritability and genetic variance of dementia with Lewy bodies.
Neurobiology of Disease
, 127
pp. 492-501.
10.1016/j.nbd.2019.04.004.
|
|
Guerreiro, R;
Orme, T;
Neto, JL;
Bras, J;
International DLB Genetics Consortium, .;
(2018)
LRP10 in alpha-synucleinopathies.
Lancet Neurology
, 17
(12)
pp. 1032-1033.
10.1016/S1474-4422(18)30399-5.
|
|
Guerreiro, R;
Ross, OA;
Kun-Rodrigues, C;
Hernandez, DG;
Orme, T;
Eicher, JD;
Shepherd, CE;
... Bras, J; + view all
(2018)
Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study.
The Lancet Neurology
, 17
(1)
pp. 64-74.
10.1016/S1474-4422(17)30400-3.
|
|
Guerreiro, RJ;
Beck, J;
Gibbs, JR;
Santana, I;
Rossor, MN;
Schott, JM;
Nalls, MA;
... Hardy, J; + view all
(2010)
Genetic Variability in CLU and Its Association with Alzheimer's Disease.
PLOS ONE
, 5
(3)
, Article e9510. 10.1371/journal.pone.0009510.
|
|
|
Guntoro, Fernando;
Viré, Emmanuelle;
Giordani, Chiara;
Darwent, Lee;
Hummerich, Holger;
Linehan, Jacqueline;
Sinka, Katy;
... Mead, Simon; + view all
(2022)
DNA methylation analysis of archival lymphoreticular tissues in Creutzfeldt–Jakob disease.
Acta Neuropathologica
10.1007/s00401-022-02481-w.
(In press).
|
|
Harding, SR;
Bocchetta, M;
Gordon, E;
Cash, DM;
Cardoso, MJ;
Druyeh, R;
Ourselin, S;
... Rohrer, JD; + view all
(2017)
The TMEM106B risk allele is associated with lower cortical volumes in a clinically diagnosed frontotemporal dementia cohort.
Journal of Neurology, Neurosurgery & Psychiatry
, 88
pp. 997-998.
10.1136/jnnp-2017-315641.
|
|
|
Hartill, VL;
van de Hoek, G;
Patel, MP;
Little, R;
Watson, CM;
Berry, IR;
Shoemark, A;
... Johnson, CA; + view all
(2017)
DNAAF1 links heart laterality with the AAA+ ATPase RUVBL1 and ciliary intraflagellar transport.
Human Molecular Genetics
10.1093/hmg/ddx422.
(In press).
|
|
|
Hassan, Shahab;
White, Kenneth;
Terry, Cassandra;
(2022)
Linking hIAPP misfolding and aggregation with type 2 diabetes mellitus: a structural perspective.
Bioscience Reports
, 42
(5)
, Article BSR20211297. 10.1042/BSR20211297.
|
|
|
Hassan, A;
Campbell, T;
Darwent, L;
Odd, H;
Green, A;
Collinge, J;
Mead, S;
(2021)
Case report of homozygous E200D mutation of PRNP in apparently sporadic Creutzfeldt-Jakob disease.
BMC Neurology
, 21
, Article 248. 10.1186/s12883-021-02274-w.
|
|
|
Heinzer, D;
Avar, M;
Pease, DP;
Dhingra, A;
Yin, J-A;
Schaper, E;
Doğançay, B;
... Aguzzi, A; + view all
(2021)
Novel regulators of PrPC biosynthesis revealed by genome-wide RNA interference.
PLoS Pathogens
, 17
(10)
, Article e1010013. 10.1371/journal.ppat.1010013.
(In press).
|
|
|
Heller, C;
Foiani, MS;
Moore, K;
Convery, R;
Bocchetta, M;
Neason, M;
Cash, DM;
... GENFI; + view all
(2020)
Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia.
Journal of Neurology, Neurosurgery and Psychiatry
10.1136/jnnp-2019-321954.
(In press).
|
|
|
Hermann, P;
Appleby, B;
Brandel, J-P;
Caughey, B;
Collins, S;
Geschwind, MD;
Green, A;
... Zerr, I; + view all
(2021)
Biomarkers and diagnostic guidelines for sporadic Creutzfeldt-Jakob disease.
The Lancet Neurology
, 20
(3)
pp. 235-246.
10.1016/S1474-4422(20)30477-4.
|
|
Hill, Elizabeth;
Cunningham, Thomas J;
(2024)
Modelling Alzheimer's disease in a dish: dissecting amyloid-β metabolism in human neurons.
Neuronal Signal
, 8
(1)
, Article NS20230020. 10.1042/NS20230020.
|
|
Holstege, Henne;
Hulsman, Marc;
Charbonnier, Camille;
Grenier-Boley, Benjamin;
Quenez, Olivier;
Grozeva, Detelina;
van Rooij, Jeroen GJ;
... Lambert, Jean-Charles; + view all
(2022)
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease.
Nature Genetics
10.1038/s41588-022-01208-7.
(In press).
|
|
Hosszu, LLP;
Conners, R;
Sangar, D;
Batchelor, M;
Sawyer, EB;
Fisher, S;
Cliff, MJ;
... Collinge, J; + view all
(2020)
Structural effects of the highly protective V127 polymorphism on human prion protein.
Communications Biology
, 3
(1)
, Article 402. 10.1038/s42003-020-01126-6.
|
|
|
Hostettler, IC;
Schwarz, G;
Ambler, G;
Wilson, D;
Banerjee, G;
Seiffge, D;
Shakeshaft, C;
... Werring, DJ; + view all
(2021)
Cerebral Small Vessel Disease and Functional Outcome Prediction after Intracerebral Haemorrhage.
Neurology
, 96
(15)
e1954-e1965.
10.1212/WNL.0000000000011746.
|
|
Hostettler, Isabel Charlotte;
Seiffge, David;
Wong, Andrew;
Ambler, Gareth;
Wilson, Duncan;
Shakeshaft, Clare;
Banerjee, Gargi;
... Werring, David; + view all
(2022)
APOE and Cerebral Small Vessel Disease Markers in Patients With Intracerebral Hemorrhage.
Neurology
, 99
(12)
e1290-e1298.
10.1212/WNL.0000000000200851.
|
|
Hu, Junhui;
Tan, Ping;
Ishihara, Moe;
Bayley, Nicholas A;
Schokrpur, Shiruyeh;
Reynoso, Jeremy G;
Zhang, Yangjun;
... Wu, Lily; + view all
(2023)
Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma.
Signal Transduction and Targeted Therapy
, 8
(1)
, Article 155. 10.1038/s41392-023-01362-2.
|
|
Hu, NW;
Nicoll, AJ;
Zhang, D;
Mably, AJ;
O'Malley, T;
Purro, SA;
Terry, C;
... Rowan, MJ; + view all
(2014)
mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo.
Nature Communications
, 5
, Article 3374. 10.1038/ncomms4374.
|
|
|
Hyare, H;
De Vita, E;
Porter, M-C;
Simpson, I;
Ridgway, G;
Lowe, J;
Thompson, A;
... Thornton, JS; + view all
(2020)
Putaminal diffusion tensor imaging measures predict disease severity across human prion diseases.
Brain Communications
, 2
(1)
, Article fcaa032. 10.1093/braincomms/fcaa032.
|
|
|
Irving, S;
Dixon, M;
Fassad, MR;
Frost, E;
Hayward, J;
Kilpin, K;
Ollosson, S;
... Bush, A; + view all
(2018)
Primary Ciliary Dyskinesia Due to Microtubular Defects is Associated with Worse Lung Clearance Index.
Lung
, 196
(2)
pp. 231-238.
10.1007/s00408-018-0086-x.
|
|
|
Jack, Kezia;
Jackson, Graham S;
Bieschke, Jan;
(2022)
Essential Components of Synthetic Infectious Prion Formation De Novo.
Biomolecules
, 12
(11)
, Article 1694. 10.3390/biom12111694.
|
|
Jackson, Graham S;
Linehan, Jacqueline;
Brandner, Sebastian;
Asante, Emmanuel A;
Wadsworth, Jonathan DF;
Collinge, John;
(2022)
Overexpression of mouse prion protein in transgenic mice causes a non-transmissible spongiform encephalopathy.
Scientific Reports
, 12
, Article 17198. 10.1038/s41598-022-21608-3.
|
|
JAT, P;
ARRAND, JR;
(1982)
Invitro transcription of 2 epstein-barr virus specified small RNA molecules.
Nucleic Acids Research
, 10
(11)
3407 - 3425.
10.1093/nar/10.11.3407.
|
|
|
JAT, P;
ROBERTS, JW;
COWIE, A;
KAMEN, R;
(1982)
Comparison of the polyoma-virus early and late promoters by transcription in vitro.
Nucleic Acids Research
, 10
(3)
871 - 887.
10.1093/nar/10.3.871.
|
|
|
Jaunmuktane, Z;
Banerjee, G;
Paine, S;
Parry-Jones, A;
Rudge, P;
Grieve, J;
Toma, AK;
... Brandner, S; + view all
(2021)
Alzheimer's disease neuropathological change three decades after iatrogenic amyloid-β transmission.
Acta Neuropathologica
10.1007/s00401-021-02326-y.
(In press).
|
|
|
Jaunmuktane, Z;
Quaegebeur, A;
Taipa, R;
Viana-Baptista, M;
Barbosa, R;
Koriath, C;
Sciot, R;
... Brandner, S; + view all
(2018)
Evidence of amyloid-β cerebral amyloid angiopathy transmission through neurosurgery.
Acta Neuropathologica
, 135
(5)
pp. 671-679.
10.1007/s00401-018-1822-2.
|
|
|
Jensen, MP;
Ziff, OJ;
Banerjee, G;
Ambler, G;
Werring, DJ;
(2019)
The impact of selective serotonin reuptake inhibitors on the risk of intracranial haemorrhage: A systematic review and meta-analysis.
European Stroke Journal
, 4
(2)
pp. 144-152.
10.1177/2396987319827211.
|
|
Jesuthasan, Aaron;
Sequeira, Danielle;
Hyare, Harpreet;
Odd, Hans;
Rudge, Peter;
Mok, Tze How;
Nihat, Akin;
... Mead, Simon; + view all
(2022)
Assessing initial MRI reports for suspected CJD patients.
Journal of Neurology
10.1007/s00415-022-11087-x.
(In press).
|
|
Jin, S;
Kedia, N;
Illes-Toth, E;
Haralampiev, I;
Prisner, S;
Herrmann, A;
Wanker, EE;
(2016)
Amyloid-β(1-42) Aggregation Initiates Its Cellular Uptake and Cytotoxicity.
Journal of Biological Chemistry
, 291
(37)
pp. 19590-19606.
10.1074/jbc.M115.691840.
|
|
|
Jiskoot, LC;
Bocchetta, M;
Nicholas, JM;
Cash, DM;
Thomas, D;
Modat, M;
Ourselin, S;
... Rohrer, JD; + view all
(2018)
Presymptomatic white matter integrity loss in familial frontotemporal dementia in the GENFI cohort: A cross-sectional diffusion tensor imaging study.
Annals of Clinical and Translational Neurology
, 5
(9)
pp. 1025-1036.
10.1002/acn3.601.
|
|
|
Joiner, S;
Asante, EA;
Linehan, JM;
Brock, L;
Brandner, S;
Bellworthy, SJ;
Simmons, MM;
... Wadsworth, JDF; + view all
(2018)
Experimental sheep BSE prions generate the vCJD phenotype when serially passaged in transgenic mice expressing human prion protein.
Journal of the Neurological Sciences
, 386
pp. 4-11.
10.1016/j.jns.2017.12.038.
|
|
|
Jones, Emma;
Hill, Elizabeth;
Linehan, Jacqueline;
Nazari, Tamsin;
Caulder, Adam;
Codner, Gemma F;
Hutchison, Marie;
... Mead, Simon; + view all
(2024)
Characterisation and prion transmission study in mice with genetic reduction of sporadic Creutzfeldt-Jakob disease risk gene Stx6.
Neurobiology of Disease
, 190
, Article 106363. 10.1016/j.nbd.2023.106363.
|
|
Jones, E;
Hummerich, H;
Viré, E;
Uphill, J;
Dimitriadis, A;
Speedy, H;
Campbell, T;
... Mead, S; + view all
(2020)
Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study.
The Lancet Neurology
, 19
(10)
pp. 840-848.
10.1016/S1474-4422(20)30273-8.
|
|
Jones, E;
Mead, S;
(2020)
Genetic risk factors for Creutzfeldt-Jakob disease.
Neurobiology of Disease
, 142
, Article 104973. 10.1016/j.nbd.2020.104973.
|
|
|
Jones, L;
Holmans, PA;
Hamshere, ML;
Harold, D;
Moskvina, V;
Ivanov, D;
Pocklington, A;
... Williams, J; + view all
(2011)
Correction: genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.
PLoS One
, 6
(2)
, Article e13950. 10.1371/journal.pone.0013950.
|
|
|
Jones, L;
Holmans, PA;
Hamshere, ML;
Harold, D;
Moskvina, V;
Ivanov, D;
Pocklington, A;
... Williams, J; + view all
(2010)
Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease.
PLOS ONE
, 5
(11)
, Article e13950. 10.1371/journal.pone.0013950.
|
|
|
Joshi, Vaibhavi;
Beecher, Kate;
Lim, Malcolm;
Stacey, Andrew;
Feng, Yufan;
Jat, Parmjit S;
Duijf, Pascal HG;
... McCart Reed, Amy E; + view all
(2024)
B7-H3 Expression in Breast Cancer and Brain Metastasis.
International Journal of Molecular Sciences
, 25
(7)
, Article 3976. 10.3390/ijms25073976.
|
|
Katrak, S;
Pauranik, A;
Desai, S;
Mead, S;
Beck, J;
Brandner, S;
Collinge, J;
(2019)
Familial Creutzfeldt-Jakob disease in an Indian kindred.
Annals of Indian Academy of Neurology
, 22
(4)
pp. 458-461.
10.4103/aian.AIAN_214_19.
|
|
|
Kedia, N;
Almisry, M;
Bieschke, J;
(2017)
Glucose directs amyloid-beta into membrane-active oligomers.
Physical Chemistry Chemical Physics
, 19
(27)
pp. 18036-18046.
10.1039/c7cp02849k.
|
|
|
Kedia, N;
Arhzaouy, K;
Pittman, SK;
Sun, Y;
Batchelor, M;
Weihl, CC;
Bieschke, J;
(2019)
Desmin forms toxic, seeding-competent amyloid aggregates that persist in muscle fibers.
Proceedings of the National Academy of Sciences of the United States of America
, 116
(34)
pp. 16835-16840.
10.1073/pnas.1908263116.
|
|
|
Kenny, J;
Woollacott, I;
Koriath, C;
Hosszu, L;
Adamson, G;
Rudge, P;
Rossor, MN;
... Mead, S; + view all
(2017)
A novel prion protein variant in a patient with semantic dementia.
[Letter].
Journal of Neurology Neurosurgery and Psychiatry
, 2017
(88)
pp. 890-892.
10.1136/jnnp-2017-315577.
|
|
|
Klyubin, I;
Nicoll, AJ;
Khalili-Shirazi, A;
Farmer, M;
Canning, S;
Mably, A;
Linehan, J;
... Collinge, J; + view all
(2014)
Peripheral Administration of a Humanized Anti-PrP Antibody Blocks Alzheimer's Disease Aβ Synaptotoxicity.
J Neurosci
, 34
(18)
6140 - 6145.
10.1523/JNEUROSCI.3526-13.2014.
|
|
|
Koriath, Carolin Anna Maria;
Guntoro, Fernando;
Norsworthy, Penelope;
Dolzhenko, Egor;
Eberle, Michael;
Hensman Moss, Davina J;
Flower, Michael;
... Wild, Edward J; + view all
(2024)
Huntington’s disease phenocopy syndromes revisited: a clinical comparison and next-generation sequencing exploration.
Journal of Neurology, Neurosurgery & Psychiatry
10.1136/jnnp-2024-333602.
(In press).
|
|
|
Koriath, C;
(2018)
Predictors for a dementia gene mutation based on gene-panel next-generation sequencing of a large dementia referral series.
Molecular Psychiatry
10.1038/s41380-018-0224-0.
(In press).
|
|
|
Koriath, C;
Lashley, T;
Taylor, W;
Druyeh, R;
Dimitriadis, A;
Denning, N;
Williams, J;
... Mead, S; + view all
(2019)
ApoE4 lowers age at onset in patients with frontotemporal dementia and tauopathy independent of amyloid-β copathology.
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
, 11
pp. 277-280.
10.1016/j.dadm.2019.01.010.
|
|
|
Koriath, CAM;
Bocchetta, M;
Brotherhood, E;
Woollacott, I;
Norsworthy, P;
Simon-Sanchez, J;
Blauwendraat, C;
... Rohrer, J; + view all
(2016)
The clinical, neuroanatomical, and neuropathologic phenotype of TBK1-associated frontotemporal dementia: A longitudinal case report.
Alzheimer's and Dementia
, 6
pp. 75-81.
10.1016/j.dadm.2016.10.003.
|
|
|
Koriath, CAM;
Kenny, J;
Ryan, NS;
Rohrer, JD;
Schott, JM;
Houlden, H;
Fox, NC;
... Mead, S; + view all
(2021)
Genetic testing in dementia — utility and clinical strategies.
Nature Reviews Neurology
, 17
pp. 23-36.
10.1038/s41582-020-00416-1.
|
|
Kotta, K;
Paspaltsis, I;
Bostantjopoulou, S;
Latsoudis, H;
Plaitakis, A;
Kazis, D;
Collinge, J;
(2006)
Novel mutation of the PRNP gene of a clinical CJD case.
BMC Infectious Diseases
, 6
, Article 169. 10.1186/1471-2334-6-169.
|
|
|
Kroll, François;
Dimitriadis, Athanasios;
Campbell, Tracy;
Darwent, Lee;
Collinge, John;
Mead, Simon;
Vire, Emmanuelle;
(2022)
Prion protein gene mutation detection using long-read Nanopore sequencing.
Scientific Reports
, 12
, Article 8284. 10.1038/s41598-022-12130-7.
|
|
Kumari, R;
Hummerich, H;
Shen, X;
Fischer, M;
Litovchick, L;
Mittnacht, S;
DeCaprio, JA;
(2021)
Simultaneous expression of MMB-FOXM1 complex components enables efficient bypass of senescence.
Scientific Reports
, 11
(1)
, Article 21506. 10.1038/s41598-021-01012-z.
|
|
|
Kumari, R;
Jat, P;
(2021)
Mechanisms of Cellular Senescence: Cell Cycle Arrest and Senescence Associated Secretory Phenotype.
Frontiers in Cell and Developmental Biology
, 9
, Article 645593. 10.3389/fcell.2021.645593.
|
|
|
Kun-Rodrigues, C;
Ganos, C;
Guerreiro, R;
Schneider, SA;
Schulte, C;
Lesage, S;
Darwent, L;
... Bras, J; + view all
(2015)
A systematic screening to identify de novo mutations causing sporadic early-onset Parkinson's disease.
Human Molecula Genetics
, 24
(23)
pp. 6711-6720.
10.1093/hmg/ddv376.
|
|
|
Kun-Rodrigues, C;
Orme, T;
Carmona, S;
Hernandez, DG;
Ross, OA;
Eicher, JD;
Shepherd, C;
... Bras, J; + view all
(2019)
A comprehensive screening of copy number variability in dementia with Lewy bodies.
Neurobiology of Aging
, 75
, Article 223.e1-223.e10. 10.1016/j.neurobiolaging.2018.10.019.
|
|
Kun-Rodrigues, C;
Ross, OA;
Orme, T;
Shepherd, C;
Parkkinen, L;
Darwent, L;
Hernandez, D;
... Bras, J; + view all
(2017)
Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.
Neurobiology of Aging
, 49
214.e13-214.e15.
10.1016/j.neurobiolaging.2016.08.023.
|
|
Kunkle, BW;
Grenier-Boley, B;
Sims, R;
Bis, JC;
Damotte, V;
Naj, AC;
Boland, A;
... Pericak-Vance, MA; + view all
(2019)
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
Nature Genetics
, 51
pp. 414-430.
10.1038/s41588-019-0358-2.
|
|
L P Hosszu, Laszlo;
Sangar, Daljit;
Batchelor, Mark;
Risse, Emmanuel;
Hounslow, Andrea M;
Collinge, John;
Waltho, Jonathan P;
(2023)
Loss of residues 119 – 136, including the first β-strand of human prion protein, generates an aggregation-competent partially “open” form.
Journal of Molecular Biology
, Article 168158. 10.1016/j.jmb.2023.168158.
(In press).
|
|
|
Larrieu, D;
Vire, E;
Robson, S;
Breusegem, SY;
Kouzarides, T;
Jackson, SP;
(2018)
Inhibition of the acetyltransferase NAT10 normalizes progeric and aging cells by rebalancing the Transportin-1 nuclear import pathway.
Science Signaling
, 11
(537)
, Article eaar5401. 10.1126/scisignal.aar5401.
|
|
|
Lashley, T;
Rohrer, JD;
Mahoney, C;
Gordon, E;
Beck, J;
Mead, S;
Warren, J;
... Revesz, T; + view all
(2013)
A pathogenic progranulin mutation and C9orf72 repeat expansion in a family with frontotemporal dementia.
Neuropathology and Applied Neurobiology
, 40
(4)
pp. 502-513.
10.1111/nan.12100.
|
|
|
Lauwers, E;
Lalli, G;
Brandner, S;
Collinge, J;
Compernolle, V;
Duyckaerts, C;
Edgren, G;
... De Strooper, B; + view all
(2020)
Potential human transmission of amyloid β pathology: surveillance and risks.
The Lancet Neurology
, 19
(10)
pp. 872-878.
10.1016/S1474-4422(20)30238-6.
|
|
Leonenko, G;
Sims, R;
Shoai, M;
Frizzati, A;
Bossu, P;
Spalletta, G;
Fox, NC;
... Munger, R; + view all
(2019)
Polygenic risk and hazard scores for Alzheimer's disease prediction.
Annals of Clinical and Translational Neurology
, 6
(3)
pp. 456-465.
10.1002/acn3.716.
|
|
|
Lim, Malcolm;
Nguyen, Tam H;
Niland, Colleen;
Reid, Lynne E;
Jat, Parmjit S;
Saunus, Jodi M;
Lakhani, Sunil R;
(2022)
Landscape of Epidermal Growth Factor Receptor Heterodimers in Brain Metastases.
Cancers
, 14
(3)
, Article 533. 10.3390/cancers14030533.
|
|
Lloyd, SE;
Maytham, EG;
Pota, H;
Grizenkova, J;
Molou, E;
Uphill, J;
Hummerich, H;
... Collinge, J; + view all
(2009)
HECTD2 Is Associated with Susceptibility to Mouse and Human Prion Disease.
PLOS GENET
, 5
(2)
, Article e1000383. 10.1371/journal.pgen.1000383.
|
|
|
Lloyd, SE;
Rossor, M;
Fox, N;
Mead, S;
Collinge, J;
(2009)
HECTD2, a candidate susceptibility gene for Alzheimer's disease on 10q.
BMC Medical Genetics
, 10
, Article 90. 10.1186/1471-2350-10-90.
|
|
|
Luk, C;
Jones, S;
Thomas, C;
Fox, NC;
Mok, TH;
Mead, S;
Collinge, J;
(2016)
Diagnosing Sporadic Creutzfeldt-Jakob Disease by the Detection of Abnormal Prion Protein in Patient Urine.
JAMA Neurology
, 73
(12)
pp. 1454-1460.
10.1001/jamaneurol.2016.3733.
|
|
Mahoney, CJ;
Beck, J;
Rohrer, JD;
Lashley, T;
Mok, K;
Shakespeare, T;
Yeatman, T;
... Warren, JD; + view all
(2012)
Frontotemporal dementia with the C9ORF72 hexanucleotide repeat expansion: clinical, neuroanatomical and neuropathological features.
Brain
, 135
(3)
736 - 750.
10.1093/brain/awr361.
|
|
|
Mahoney, CJ;
Downey, LE;
Beck, J;
Liang, Y;
Mead, S;
Perry, RJ;
Warren, JD;
(2013)
The Presenilin 1 P264L Mutation Presenting as non-Fluent/Agrammatic Primary Progressive Aphasia.
Journal of Alzheimer’s Disease
, 36
pp. 239-243.
10.3233/JAD-122092.
|
|
|
Mahoney, CJ;
Ridgway, GR;
Malone, IB;
Downey, LE;
Beck, J;
Kinnunen, KM;
Schmitz, N;
... Warren, JD; + view all
(2014)
Profiles of white matter tract pathology in frontotemporal dementia.
Hum Brain Mapp
, 35
(8)
pp. 4163-4179.
10.1002/hbm.22468.
|
|
|
Majbour, Nour;
Aasly, Jan;
Abdi, Ilham;
Ghanem, Simona;
Erskine, Daniel;
van de Berg, Wilma;
El-Agnaf, Omar;
(2022)
Disease-Associated α-Synuclein Aggregates as Biomarkers of Parkinson Disease Clinical Stage.
Neurology
10.1212/WNL.0000000000201199.
(In press).
|
|
Majounie, E;
Renton, AE;
Mok, K;
Dopper, EG;
Waite, A;
Rollinson, S;
Chiò, A;
... Traynor, BJ; + view all
(2012)
Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study.
Lancet Neurology
, 11
(4)
323 - 330.
10.1016/S1474-4422(12)70043-1.
|
|
|
Manera, AL;
Dadar, M;
Van Swieten, JC;
Borroni, B;
Sanchez-Valle, R;
Moreno, F;
Laforce, R;
... GENFI Consortium, .; + view all
(2021)
MRI data-driven algorithm for the diagnosis of behavioural variant frontotemporal dementia.
Journal of Neurology, Neurosurgery & Psychiatry
, 92
(6)
pp. 608-616.
10.1136/jnnp-2020-324106.
|
|
|
Manka, SW;
Brew, K;
(2020)
Thermodynamic and Mechanistic Insights into Coupled Binding and Unwinding of Collagen by Matrix Metalloproteinase 1.
Journal of Molecular Biology
, 432
(22)
pp. 5985-5993.
10.1016/j.jmb.2020.10.003.
|
|
Manka, Szymon W;
(2023)
Structural insights into how augmin augments the mitotic spindle.
Nature Communications
, 14
, Article 2073. 10.1038/s41467-023-37625-3.
|
|
Manka, Szymon W;
Wenborn, Adam;
Betts, Jemma;
Joiner, Susan;
Saibil, Helen R;
Collinge, John;
Wadsworth, Jonathan DF;
(2023)
A structural basis for prion strain diversity.
Nature Chemical Biology
10.1038/s41589-022-01229-7.
(In press).
|
|
Manka, Szymon W;
Wenborn, Adam;
Collinge, John;
Wadsworth, Jonathan DF;
(2022)
Prion strains viewed through the lens of cryo-EM.
Cell and Tissue Research
10.1007/s00441-022-03676-z.
(In press).
|
|
Manka, Szymon W;
Zhang, Wenjuan;
Wenborn, Adam;
Betts, Jemma;
Joiner, Susan;
Saibil, Helen R;
Collinge, John;
(2022)
2.7 Å cryo-EM structure of ex vivo RML prion fibrils.
Nat Commun
, 13
, Article 4004. 10.1038/s41467-022-30457-7.
|
|
Manka, SW;
Bihan, D;
Farndale, RW;
(2019)
Structural studies of the MMP-3 interaction with triple-helical collagen introduce new roles for the enzyme in tissue remodelling.
Scientific Reports
, 9
(1)
, Article 18785. 10.1038/s41598-019-55266-9.
|
|
|
Manka, SW;
Moores, CA;
(2020)
Pseudo-repeats in doublecortin make distinct mechanistic contributions to microtubule regulation.
EMBO Reports
, Article e51534. 10.15252/embr.202051534.
|
|
|
Manka, SW;
Moores, CA;
(2018)
Microtubule structure by cryo-EM: snapshots of dynamic instability.
Essays in Biochemistry
, 62
(6)
pp. 737-751.
10.1042/EBC20180031.
|
|
|
Manka, SW;
Moores, CA;
(2018)
The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability.
Nature Structural & Molecular Biology
, 25
(7)
pp. 607-615.
10.1038/s41594-018-0087-8.
|
|
|
Marbiah, MM;
Harvey, A;
West, BT;
Louzolo, A;
Banerjee, P;
Alden, J;
Grigoriadis, A;
... Klöhn, PC; + view all
(2014)
Identification of a gene regulatory network associated with prion replication.
The EMBO Journal
, 33
(14)
1503- 1614.
10.15252/embj.201387150.
|
|
|
Marzo, A;
Galli, S;
Lopes, D;
McLeod, F;
Podpolny, M;
Segovia-Roldan, M;
Ciani, L;
... Salinas, PC; + view all
(2016)
Reversal of Synapse Degeneration by Restoring Wnt Signaling in the Adult Hippocampus.
Current Biology
, 26
(19)
pp. 2551-2561.
10.1016/j.cub.2016.07.024.
|
|
McKinnon, C;
Goold, R;
Andre, R;
Devoy, A;
Ortega, Z;
Moonga, J;
Linehan, JM;
... Tabrizi, SJ; + view all
(2016)
Prion-mediated neurodegeneration is associated with early impairment of the ubiquitin-proteasome system.
Acta Neuropathologica
, 131
(3)
pp. 411-425.
10.1007/s00401-015-1508-y.
|
|
|
McNaughton, D;
Knight, W;
Guerreiro, R;
Ryan, N;
Lowe, J;
Poulter, M;
Nicholl, DJ;
... Mead, S; + view all
(2012)
Duplication of amyloid precursor protein (APP), but not prion protein (PRNP) gene is a significant cause of early onset dementia in a large UK series.
Neurobioly of Aging
, 33
(2)
426.e13 - 426.e21.
10.1016/j.neurobiolaging.2010.10.010.
|
|
|
McNiven, K;
Nihat, A;
Mok, TH;
Tesfamichael, S;
O’Donnell, V;
Rudge, P;
Collinge, J;
(2019)
Enteral feeding is associated with longer survival in the advanced stages of prion disease.
Brain Communications
, 1
(1)
, Article fcz012. 10.1093/braincomms/fcz012.
|
|
|
Mead, S;
(2021)
The Intractable Puzzle of Sporadic Creutzfeldt-Jakob Disease in Very Young People.
Neurology
, 97
(17)
pp. 801-802.
10.1212/wnl.0000000000012739.
|
|
Mead, S;
Evans, T;
(2021)
Safe laboratory management of prions and proteopathic seeds.
The Lancet Neurology
, 20
(12)
, Article 981. 10.1016/S1474-4422(21)00379-3.
|
|
Mead, S;
Khalili-Shirazi, A;
Potter, C;
Mok, T;
Nihat, A;
Hyare, H;
Canning, S;
... Collinge, J; + view all
(2022)
Prion protein monoclonal antibody (PRN100) therapy for Creutzfeldt–Jakob disease: evaluation of a first-in-human treatment programme.
The Lancet Neurology
, 21
(4)
pp. 342-354.
10.1016/S1474-4422(22)00082-5.
|
|
Mead, Simon;
Fox, Nick C;
(2023)
Lecanemab slows Alzheimer's disease: hope and challenges.
Lancet Neurology
, 22
(2)
pp. 106-108.
10.1016/S1474-4422(22)00529-4.
|
|
Mead, S;
(2020)
Marked abnormalities of plasma protein biomarkers in Creutzfeldt-Jakob disease (CJD).
Journal of Neurology, Neurosurgery and Psychiatry
10.1136/jnnp-2020-324307.
(In press).
|
|
|
Mead, S;
Burnell, M;
Lowe, J;
Thompson, A;
Lukic, A;
Porter, MC;
Carswell, C;
... Collinge, J; + view all
(2016)
Clinical Trial Simulations Based on Genetic Stratification and the Natural History of a Functional Outcome Measure in Creutzfeldt-Jakob Disease.
JAMA Neurology
, 73
(4)
pp. 447-455.
10.1001/jamaneurol.2015.4885.
|
|
Mead, S;
Gandhi, S;
Beck, J;
Caine, D;
Gallujipali, D;
Carswell, C;
Hyare, H;
... Collinge, J; + view all
(2013)
A Novel Prion Disease Presenting with Diarrhea and Autonomic Neuropathy.
New England Journal of Medicine
, 369
(20)
1904- 1914.
10.1056/NEJMoa1214747.
|
|
|
Mead, S;
Lloyd, S;
Collinge, J;
(2019)
Genetic Factors in Mammalian Prion Diseases.
Annual Review of Genetics
, 53
, Article 21. 10.1146/annurev-genet-120213-092352.
(In press).
|
|
Mead, S;
Rudge, P;
(2017)
CJD mimics and chameleons.
Practical Neurology
, 17
(2)
pp. 113-121.
10.1136/practneurol-2016-001571.
|
|
Mengel, D;
Mok, TH;
Nihat, A;
Liu, W;
Rissman, RA;
Galasko, D;
Zetterberg, H;
... Walsh, DM; + view all
(2021)
NT1-Tau Is Increased in CSF and Plasma of CJD Patients, and Correlates with Disease Progression.
Cells
, 10
(12)
, Article 3514. 10.3390/cells10123514.
|
|
|
Mengel, D;
Hong, W;
Corbett, GT;
Liu, W;
DeSousa, A;
Solforosi, L;
Fang, C;
... Walsh, DM; + view all
(2019)
PrP-grafted antibodies bind certain amyloid β-protein aggregates, but do not prevent toxicity.
Brain Research
, 1710
pp. 125-135.
10.1016/j.brainres.2018.12.038.
|
|
Mensah, A;
Mulligan, C;
Linehan, J;
Ruf, S;
O'Doherty, A;
Grygalewicz, B;
Shipley, J;
... Nizetic, D; + view all
(2007)
An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model.
BMC Developmental Biology
, 7
, Article 131. 10.1186/1471-213X-7-131.
|
|
|
Milanesi, L;
Trevitt, CR;
Whitehead, B;
Hounslow, AM;
Tomas, S;
Hosszu, LLP;
Hunter, CA;
(2021)
High-affinity tamoxifen analogues retain extensive positional disorder when bound to calmodulin.
Magnetic Resonance
, 2
(2)
pp. 629-642.
10.5194/mr-2-629-2021.
|
|
Minikel, EV;
Vallabh, SM;
Orseth, MC;
Brandel, J-P;
Haïk, S;
Laplanche, J-L;
Zerr, I;
... Mead, S; + view all
(2019)
Age at onset in genetic prion disease and the design of preventive clinical trials.
Neurology
, 93
(2)
e125-e134.
10.1212/WNL.0000000000007745.
|
|
Mirabile, I;
Jat, PS;
Brandner, S;
Collinge, J;
(2015)
Identification of clinical target areas in the brainstem of prion-infected mice.
Neuropathology and Applied Neurobiology
, 41
(5)
pp. 613-630.
10.1111/nan.12189.
|
|
|
Mitchison, H;
(2019)
Clinical utility of NGS diagnosis and disease stratification in a multi-ethnic primary ciliary dyskinesia cohort.
Journal of Medical Genetics
10.1136/jmedgenet-2019-106501.
(In press).
|
|
Mizielinska, S;
Grönke, S;
Niccoli, T;
Ridler, CE;
Clayton, EL;
Devoy, A;
Moens, T;
... Isaacs, AM; + view all
(2014)
C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins.
Science
10.1126/science.1256800.
|
|
|
Mok, Tze How;
Nihat, Akin;
Majbour, Nour;
Sequeira, Danielle;
Holm-Mercer, Leah;
Coysh, Thomas;
Darwent, Lee;
... Mead, Simon; + view all
(2023)
Seed amplification and neurodegeneration marker trajectories in individuals at risk of prion disease.
Brain
, Article awad101. 10.1093/brain/awad101.
|
|
|
Mok, T;
Jaunmuktane, Z;
Joiner, S;
Campbell, T;
Morgan, C;
Wakerley, B;
Golestani, F;
... Collinge, J; + view all
(2017)
Variant Creutzfeldt-Jakob Disease in a Patient with Heterozygosity at PRNP Codon 129.
The New England Journal of Medicine
, 376
(3)
pp. 292-294.
10.1056/NEJMc1610003.
|
|
Mok, TH;
Koriath, C;
Jaunmuktane, Z;
Campbell, T;
Joiner, S;
Wadsworth, JDF;
Hosszu, LLP;
... Mead, S; + view all
(2018)
Evaluating the causality of novel sequence variants in the prion protein gene by example.
Neurobiology of Aging
, 71
265.e1-265.e7.
10.1016/j.neurobiolaging.2018.05.011.
|
|
|
Mok, TH;
Mead, S;
(2020)
Preclinical biomarkers of prion infection and neurodegeneration.
Current Opinion in Neurobiology
, 61
pp. 82-88.
10.1016/j.conb.2020.01.009.
|
|
Mok, TH;
Nihat, A;
Luk, C;
Sequeira, D;
Batchelor, M;
Mead, S;
Collinge, J;
(2021)
Bank vole prion protein extends the use of RT-QuIC assays to detect prions in a range of inherited prion diseases.
Scientific Reports
, 11
(1)
, Article 5231. 10.1038/s41598-021-84527-9.
|
|
|
Mole, J;
Mead, S;
Rudge, P;
Nihat, A;
Mok, T;
Collinge, J;
Caine, D;
(2021)
Cognitive decline heralds onset of symptomatic inherited prion disease.
Brain
, 144
(3)
pp. 989-998.
10.1093/brain/awaa409.
|
 |
|
Moore, K;
Convery, R;
Bocchetta, M;
Neason, M;
Cash, DM;
Greaves, C;
Russell, LL;
... Anderl-Straub, S; + view all
(2020)
A modified Camel and Cactus Test detects presymptomatic semantic impairment in genetic frontotemporal dementia within the GENFI cohort.
Applied Neuropsychology: Adult
10.1080/23279095.2020.1716357.
(In press).
|
|
Moore, KM;
Nicholas, J;
Grossman, M;
McMillan, CT;
Irwin, DJ;
Massimo, L;
Van Deerlin, VM;
... Geschwind, D; + view all
(2019)
Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study.
The Lancet Neurology
10.1016/s1474-4422(19)30394-1.
(In press).
|
|
|
Moss, DJH;
Pardinas, AF;
Langbehn, D;
Lo, K;
Leavitt, BR;
Roos, R;
Durr, A;
... Tabrizi, SJ; + view all
(2017)
Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study.
Lancet Neurology
, 16
(9)
pp. 701-711.
10.1016/S1474-4422(17)30161-8.
|
|
Moss, DJH;
Poulter, M;
Beck, J;
Hehir, J;
Polke, JM;
Campbell, T;
Adamson, G;
... Tabrizi, SJ; + view all
(2014)
C9orf72 expansions are the most common genetic cause of Huntington disease phenocopies.
Neurology
, 82
(4)
pp. 292-299.
10.1212/WNL.0000000000000061.
|
|
Mutsaerts, HJMM;
Mirza, SS;
Petr, J;
Thomas, DL;
Cash, DM;
Bocchetta, M;
de Vita, E;
... GENFI consortium, .; + view all
(2019)
Cerebral perfusion changes in presymptomatic genetic frontotemporal dementia: a GENFI study.
Brain. A Journal of Neurology
10.1093/brain/awz039.
(In press).
|
|
Nahass, GR;
Sun, Y;
Xu, Y;
Batchelor, M;
Reilly, M;
Benilova, I;
Kedia, N;
... Bieschke, J; + view all
(2021)
Brazilin Removes Toxic Alpha-Synuclein and Seeding Competent Assemblies from Parkinson Brain by Altering Conformational Equilibrium.
Journal of Molecular Biology
, 433
(8)
, Article 166878. 10.1016/j.jmb.2021.166878.
|
|
Nicoll, AJ;
Panico, S;
Freir, DB;
Wright, D;
Terry, C;
Risse, E;
Herron, CE;
... Collinge, J; + view all
(2013)
Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity.
Nature Communications
, 4
, Article 2416 . 10.1038/ncomms3416.
|
|
|
Nihat, A;
Mok, TH;
Odd, H;
Thompson, AGB;
Caine, D;
McNiven, K;
O'Donnell, V;
... Mead, S; + view all
(2022)
Development of novel clinical examination scales for the measurement of disease severity in Creutzfeldt-Jakob disease.
Journal of Neurology, Neurosurgery & Psychiatry
10.1136/jnnp-2021-327722.
(In press).
|
|
|
Nihat, Akın;
Ranson, Janice M;
Harris, Dominique;
McNiven, Kirsty;
Mok, TzeHow;
Rudge, Peter;
Collinge, John;
... Mead, Simon; + view all
(2022)
Development of prognostic models for survival and care status in sporadic Creutzfeldt-Jakob disease.
Brain Communications
, 4
(4)
, Article fcac201. 10.1093/braincomms/fcac201.
|
|
Nihat, A;
de Lusignan, S;
Thomas, N;
Tahir, MA;
Gallagher, H;
(2016)
What drives quality improvement in chronic kidney disease (CKD) in primary care: process evaluation of the Quality Improvement in Chronic Kidney Disease (QICKD) trial.
BMJ Open
, 6
(4)
, Article e008480. 10.1136/bmjopen-2015-008480.
|
|
|
Nihat, A;
Mead, S;
(2018)
Detection of Creutzfeldt-Jakob disease prions in skin: implications for healthcare.
Genome Medicine
, 10
(1)
, Article 22. 10.1186/s13073-018-0536-3.
|
|
|
Norsworthy, PJ;
Thompson, AGB;
Mok, TH;
Guntoro, F;
Dabin, LC;
Nihat, A;
Paterson, RW;
... Viré, EA; + view all
(2020)
A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis.
Nature Communications
, 11
(1)
, Article 3960. 10.1038/s41467-020-17655-x.
|
|
|
O'Connor, A;
Abel, E;
Fraser, MR;
Ryan, NS;
Jiménez, DA;
Koriath, C;
Chávez-Gutiérrez, L;
... Fox, NC; + view all
(2021)
A novel presenilin 1 duplication mutation (Ile168dup) causing Alzheimer's disease associated with myoclonus, seizures and pyramidal features.
Neurobiology of Aging
, 103
137.e1-137.e5.
10.1016/j.neurobiolaging.2021.01.032.
|
|
O'Connor, A;
Karikari, TK;
Poole, T;
Ashton, NJ;
Rodriguez, JL;
Khatun, A;
Swift, I;
... Fox, NC; + view all
(2020)
Plasma phospho-tau181 in presymptomatic and symptomatic familial Alzheimer's disease: a longitudinal cohort study.
Molecular Psychiatry
10.1038/s41380-020-0838-x.
(In press).
|
|
O'Connor, A;
Pannee, J;
Poole, T;
Arber, C;
Portelius, E;
Swift, IJ;
Heslegrave, AJ;
... Fox, NC; + view all
(2021)
Plasma amyloid-β ratios in autosomal dominant Alzheimer's disease: the influence of genotype.
Brain
10.1093/brain/awab166.
(In press).
|
|
|
Olcese, C;
Patel, MP;
Shoemark, A;
Kiviluoto, S;
Legendre, M;
Williams, HJ;
Vaughan, CK;
... Mitchison, HM; + view all
(2017)
X-linked primary ciliary dyskinesia due to mutations in the cytoplasmic axonemal dynein assembly factor PIH1D3.
Nature Communications
, 8
, Article 14279. 10.1038/ncomms14279.
|
|
|
Onoufriadis, A;
Shoemark, A;
Munye, MM;
James, CT;
Schmidts, M;
Patel, M;
Rosser, EM;
... Mitchison, HM; + view all
(2013)
Combined exome and whole-genome sequencing identifies mutations in ARMC4 as a cause of primary ciliary dyskinesia with defects in the outer dynein arm.
Journal of Medical Genetics
10.1136/jmedgenet-2013-101938.
|
 |
|
Onoufriadis, A;
Shoemark, A;
Schmidts, M;
Patel, M;
Jimenez, G;
Liu, H;
Thomas, B;
... Mitchison, HM; + view all
(2014)
Targeted NGS gene panel identifies mutations in RSPH1 causing primary ciliary dyskinesia and a common mechanism for ciliary central-pair agenesis due to radial spoke defects.
Hum Mol Genet
, 23
(13)
pp. 3362-3374.
10.1093/hmg/ddu046.
|
|
|
Orme, T;
Hernandez, D;
Ross, OA;
Kun-Rodrigues, C;
Darwent, L;
Shepherd, CE;
Parkkinen, L;
... Bras, J; + view all
(2020)
Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies.
Acta Neuropathologica Communications
, 8
(1)
, Article 5. 10.1186/s40478-020-0879-z.
|
|
|
Owen, J;
Beck, J;
Campbell, T;
Adamson, G;
Gorham, M;
Thompson, A;
Smithson, S;
... Mead, S; + view all
(2014)
Predictive testing for inherited prion disease: report of 22 years experience.
European Journal of Human Genetics
, 22
(12)
pp. 1351-1356.
10.1038/ejhg.2014.42.
|
|
Ozkan, H;
Ambler, G;
Banerjee, G;
Chan, E;
Browning, S;
Mitchell, J;
Perry, R;
... SIGNaL collaborators, .; + view all
(2021)
The impact of the UK COVID-19 pandemic on patient-reported health outcomes after stroke: a retrospective sequential comparison.
Journal of Neurology
10.1007/s00415-021-10819-9.
(In press).
|
|
|
Ozkan, Hatice;
Ambler, Gareth;
Banerjee, Gargi;
Browning, Simone;
Leff, Alex P;
Ward, Nick S;
Simister, Robert;
... MRC Prion Unit at UCL, .; + view all
(2023)
Prevalence, patterns, and predictors of patient-reported non-motor outcomes at 30 days after acute stroke: prospective observational hospital cohort study.
International Journal of Stroke
10.1177/17474930231215660.
(In press).
|
|
Panteleienko, L;
Mallon, D;
Htet, CMM;
Lizak, N;
Zandi, M;
Banerjee, G;
Werring, DJ;
(2025)
Cerebral Amyloid Angiopathy-Related Inflammation in Iatrogenic Cerebral Amyloid Angiopathy.
European Journal of Neurology
, 32
(5)
, Article e70198. 10.1111/ene.70198.
|
|
|
Panteleienko, Larysa;
Mallon, Dermot;
Oliver, Rupert;
Toosy, Ahmed;
Hoshino, Yuki;
Murakami, Aya;
Kaushik, Kanishk;
... Werring, David J; + view all
(2024)
Iatrogenic cerebral amyloid angiopathy in older adults.
European Journal of Neurology
, Article e16278. 10.1111/ene.16278.
(In press).
|
|
Peakman, G;
Russell, LL;
Convery, RS;
Nicholas, JM;
van Swieten, JC;
Jiskoot, LC;
Moreno, F;
... Mitchell, S; + view all
(2021)
Comparison of clinical rating scales in genetic frontotemporal dementia within the GENFI cohort.
Journal of Neurology, Neurosurgery and Psychiatry
10.1136/jnnp-2021-326868.
(In press).
|
|
|
Peloso, GM;
van der Lee, SJ;
Sims, R;
van der Lee, SJ;
Naj, AC;
Bellenguez, C;
Badarinarayan, N;
... Crane, PK; + view all
(2018)
Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease.
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
, 10
pp. 595-598.
10.1016/j.dadm.2018.08.008.
|
|
|
Pfister, KK;
Shah, PR;
Hummerich, H;
Russ, A;
Cotton, J;
Annuar, AA;
King, SM;
(2006)
Genetic analysis of the cytoplasmic dynein subunit families.
PLoS Genetics
, 2
(1)
, Article E1. 10.1371/journal.pgen.0020001.
|
|
|
Philiastides, A;
Ribes, JM;
Yip, DC-M;
Schmidt, C;
Benilova, I;
Klöhn, P-C;
(2019)
A New Cell Model for Investigating Prion Strain Selection and Adaptation.
Viruses
, 11
(10)
, Article 888. 10.3390/v11100888.
|
|
|
Poos, JM;
Russell, LL;
Peakman, G;
Bocchetta, M;
Greaves, CV;
Jiskoot, LC;
van der Ende, EL;
... Genetic FTD Initiative, GENF; + view all
(2021)
Impairment of episodic memory in genetic frontotemporal dementia: A GENFI study.
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
, 13
(1)
, Article e12185. 10.1002/dad2.12185.
|
|
|
Pottier, C;
Ren, Y;
Perkerson, RB;
Baker, M;
Jenkins, GD;
Van Blitterswijk, M;
DeJesus-Hernandez, M;
... Rademakers, R; + view all
(2019)
Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.
Acta Neuropathologica
, 137
(6)
pp. 879-899.
10.1007/s00401-019-01962-9.
|
|
|
Pottier, C;
Zhou, X;
Perkerson, RB;
Baker, M;
Jenkins, GD;
Serie, DJ;
Ghidoni, R;
... Rademakers, R; + view all
(2018)
Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.
The Lancet Neurology
, 17
(6)
pp. 548-558.
10.1016/S1474-4422(18)30126-1.
|
|
Properzi, F;
Badhan, A;
Klier, S;
Schmidt, C;
Klohn, PC;
Wadsworth, JDF;
Clarke, AR;
... Collinge, J; + view all
(2016)
Physical, chemical and kinetic factors affecting prion infectivity.
Prion
, 10
(3)
pp. 251-261.
10.1080/19336896.2016.1181250.
|
|
|
Purro, Silvia A;
Farmer, Michael;
Noble, Elizabeth;
Sarell, Claire J;
Powell, Megan;
Yip, Daniel;
Giggins, Lauren;
... Collinge, John; + view all
(2023)
Two mouse models of Alzheimer's disease accumulate amyloid at different rates and have distinct Aβ oligomer profiles unaltered by ablation of cellular prion protein.
PLoS One
, 18
(11)
, Article e0294465. 10.1371/journal.pone.0294465.
|
|
Purro, SA;
Farrow, MA;
Linehan, J;
Nazari, T;
Thomas, DX;
Chen, Z;
Mengel, D;
... Collinge, J; + view all
(2018)
Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone.
Nature
, 564
(7736)
pp. 415-419.
10.1038/s41586-018-0790-y.
|
|
Purro, SA;
Galli, S;
Salinas, PC;
(2014)
Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases.
Journal of Molecular Cell Biology
, 6
(1)
pp. 75-80.
10.1093/jmcb/mjt049.
|
|
|
Qiang, W;
Yau, W-M;
Lu, J-X;
Collinge, J;
Tycko, R;
(2017)
Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes.
Nature
, 541
(7636)
pp. 217-221.
10.1038/nature20814.
|
|
Quinn, L;
Whitfield, J;
Alpers, MP;
Campbell, T;
Hummerich, H;
Pomat, W;
Siba, P;
... Mead, S; + view all
(2024)
Population structure and migration in the Eastern Highlands of Papua New Guinea, a region impacted by the kuru epidemic.
American Journal of Human Genetics
, 111
(4)
pp. 668-679.
10.1016/j.ajhg.2024.02.011.
|
|
Rai, A;
Liu, T;
Katrukha, EA;
Estévez-Gallego, J;
Manka, SW;
Paterson, I;
Díaz, JF;
... Akhmanova, A; + view all
(2021)
Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes.
Proceedings of the National Academy of Sciences
, 118
(51)
, Article e2112261118. 10.1073/pnas.2112261118.
|
|
|
Ramberger, Melanie;
Berretta, Antonio;
Tan, Jeanne MM;
Sun, Bo;
Michael, Sophia;
Yeo, Tianrong;
Theorell, Jakob;
... Irani, Sarosh R; + view all
(2020)
Distinctive binding properties of human monoclonal LGI1 autoantibodies determine pathogenic mechanisms.
Brain
, 143
(6)
pp. 1731-1745.
10.1093/brain/awaa104.
|
|
|
Rayner, MLD;
Day, AGE;
Bhangra, KS;
Sinden, J;
Phillips, JB;
(2021)
Engineered neural tissue made using clinical-grade human neural stem cells supports regeneration in a long gap peripheral nerve injury model.
Acta Biomaterialia
, 135
pp. 203-213.
10.1016/j.actbio.2021.08.030.
|
|
Rayner, MLD;
Healy, J;
Phillips, JB;
(2021)
Repurposing small molecules to target ppar-γ as new therapies for peripheral nerve injuries.
Biomolecules
, 11
(9)
, Article 1301. 10.3390/biom11091301.
|
|
|
Rayner, MLD;
Brown, HL;
Wilcox, M;
Phillips, JB;
Quick, TJ;
(2020)
Quantifying regeneration in patients following peripheral nerve injury.
Journal of Plastic, Reconstructive & Aesthetic Surgery
, 73
(2)
pp. 201-208.
10.1016/j.bjps.2019.10.007.
|
|
Rayner, MLD;
Grillo, A;
Williams, G;
Tawfik, E;
Zhang, T;
Volitaki, C;
Craig, DQM;
... Phillips, J; + view all
(2020)
Controlled local release of PPARγ agonists from biomaterials to treat peripheral nerve injury.
Journal of Neural Engineering
10.1088/1741-2552/aba7cc.
(In press).
|
|
|
Rayner, MLD;
Laranjeira, S;
Evans, RE;
Shipley, RJ;
Healy, J;
Phillips, JB;
(2018)
Developing an In Vitro Model to Screen Drugs for Nerve Regeneration.
Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
, 301
(10)
pp. 1628-1637.
10.1002/ar.23918.
|
|
|
Reilly, Madeleine;
Benilova, Iryna;
Khalili-Shirazi, Azadeh;
Schmidt, Christian;
Ahmed, Parvin;
Yip, Daniel;
Jat, Parmjit S;
(2022)
A high-content neuron imaging assay demonstrates inhibition of prion disease-associated neurotoxicity by an anti-prion protein antibody.
Scientific Reports
, 12
, Article 9493. 10.1038/s41598-022-13455-z.
|
|
Reus, LM;
Pasaniuc, B;
Posthuma, D;
Boltz, T;
Pijnenburg, YAL;
Ophoff, RA;
(2021)
Gene Expression Imputation Across Multiple Tissue Types Provides Insight Into the Genetic Architecture of Frontotemporal Dementia and Its Clinical Subtypes.
Biological Psychiatry
, 89
(8)
pp. 825-835.
10.1016/j.biopsych.2020.12.023.
|
|
|
Ribes, Juan Manuel;
Patel, Mitali P;
Halim, Hazim A;
Berretta, Antonio;
Tooze, Sharon A;
Klöhn, Peter-Christian;
(2023)
Prion protein conversion at two distinct cellular sites precedes fibrillisation.
Nature Communications
, 14
, Article 8354. 10.1038/s41467-023-43961-1.
|
|
Risse, E;
Nicoll, AJ;
Taylor, WA;
Wright, D;
Badoni, M;
Yang, X;
Farrow, MA;
(2015)
Identification of a Compound That Disrupts Binding of Amyloid-β to the Prion Protein Using a Novel Fluorescence-based Assay.
Journal of Biological Chemistry
, 290
(27)
pp. 17020-17028.
10.1074/jbc.M115.637124.
|
|
|
Rittman, T;
Borchert, R;
Jones, S;
van Swieten, J;
Borroni, B;
Galimberti, D;
Masellis, M;
... Genetic Frontotemporal Dementia Initiative (GENFI); + view all
(2019)
Functional network resilience to pathology in presymptomatic genetic frontotemporal dementia.
Neurobiology of Aging
, 77
pp. 169-177.
10.1016/j.neurobiolaging.2018.12.009.
|
|
|
Robson, EA;
Dixon, L;
Causon, L;
Dawes, W;
Benenati, M;
Fassad, M;
Hirst, RA;
... O'Callaghan, C; + view all
(2020)
Hydrocephalus and diffuse choroid plexus hyperplasia in primary ciliary dyskinesia-related MCIDAS mutation.
Neurology: Genetics
, 6
(4)
, Article e482. 10.1212/NXG.0000000000000482.
|
|
|
Rocha-Ferreira, E;
Sisa, C;
Bright, S;
Fautz, T;
Harris, M;
Riquelme, IC;
Agwu, C;
... Hristova, M; + view all
(2019)
Curcumin: Novel Treatment in Neonatal Hypoxic-Ischemic Brain Injury.
Frontiers In Physiology
, 10
, Article 1351. 10.3389/fphys.2019.01351.
|
|
|
Rohrer, JD;
Beck, J;
Plagnol, V;
Gordon, E;
Lashley, T;
Revesz, T;
Janssen, JC;
... Schott, JM; + view all
(2013)
Exome sequencing reveals a novel partial deletion in the progranulin gene causing primary progressive aphasia.
J Neurol Neurosurg Psychiatry
, 84
(12)
pp. 1411-1412.
10.1136/jnnp-2013-306116.
|
|
|
Rohrer, JD;
Nicholas, JM;
Cash, DM;
van Swieten, J;
Dopper, E;
Jiskoot, L;
van Minkelen, R;
... Rossor, MN; + view all
(2015)
Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis.
Lancet Neurol
, 14
(3)
253 - 262.
10.1016/S1474-4422(14)70324-2.
|
|
|
Rohrer, JD;
Woollacott, IOC;
Dick, KM;
Brotherhood, E;
Gordon, E;
Fellows, A;
Toombs, J;
... Zetterberg, H; + view all
(2016)
Serum neurofilament light chain protein is a measure of disease intensity in frontotemporal dementia.
NEUROLOGY
, 87
(13)
pp. 1329-1336.
10.1212/WNL.0000000000003154.
|
|
|
Roos, P;
Johannsen, P;
Lindquist, SG;
Brown, JM;
Waldemar, G;
Duno, M;
Nielsen, TT;
... Nielsen, JE; + view all
(2022)
Six generations of CHMP2B-mediated Frontotemporal Dementia: Clinical features, predictive testing, progression, and survival.
Acta Neurologica Scandinavica
, 145
(5)
pp. 529-540.
10.1111/ane.13578.
|
|
Rossi, M;
Mead, S;
Collinge, J;
Rudge, P;
Vincent, A;
(2015)
Neuronal antibodies in patients with suspected or confirmed sporadic Creutzfeldt-Jakob Disease.
Journal of Neurology, Neurosurgery, and Psychiatry
, 86
(6)
pp. 692-694.
10.1136/jnnp-2014-308695.
|
|
Rostgaard, N;
Roos, P;
Budtz-Jorgensen, E;
Johannsen, P;
Waldemar, G;
Norremolle, A;
Lindquist, SG;
... Nielsen, JE; + view all
(2017)
TMEM106B and ApoE polymorphisms in CHMP2B-mediated frontotemporal dementia (FTD-3).
Neurobiology of Aging
, 59
221.e1-221.e7.
10.1016/j.neurobiolaging.2017.06.026.
|
|
Rovillain, E;
Mansfield, L;
Lord, CJ;
Ashworth, A;
Jat, PS;
(2011)
An RNA interference screen for identifying downstream effectors of the p53 and pRB tumour suppressor pathways involved in senescence.
BMC GENOMICS
, 12
, Article 355. 10.1186/1471-2164-12-355.
|
|
|
Rudge, P;
Hyare, H;
Green, A;
Collinge, J;
Mead, S;
(2018)
Imaging and CSF analyses effectively distinguish CJD from its mimics.
Journal of Neurology, Neurosurgery, and Psychiatry
, 89
(5)
pp. 461-466.
10.1136/jnnp-2017-316853.
|
|
Rudge, P;
Jaunmuktane, Z;
Adlard, P;
Bjurstrom, N;
Caine, D;
Lowe, J;
Norsworthy, P;
... Collinge, J; + view all
(2015)
Iatrogenic CJD due to pituitary-derived growth hormone with genetically determined incubation times of up to 40 years.
Brain
, 138
(Pt 11)
pp. 3386-3399.
10.1093/brain/awv235.
|
|
|
Rudge, P;
Jaunmuktane, Z;
Hyare, H;
Ellis, M;
Koltzenburg, M;
Collinge, J;
Brandner, S;
(2019)
Early neurophysiological biomarkers and spinal cord pathology in inherited prion disease.
Brain
10.1093/brain/awy358.
(In press).
|
|
|
Russell, LL;
Greaves, CV;
Bocchetta, M;
Nicholas, J;
Convery, RS;
Moore, K;
Cash, DM;
... Anderl-Straub, S; + view all
(2020)
Social cognition impairment in genetic frontotemporal dementia within the GENFI cohort.
Cortex
10.1016/j.cortex.2020.08.023.
(In press).
|
|
|
Ryan, NS;
Nicholas, JM;
Weston, PSJ;
Liang, Y;
Lashley, T;
Guerreiro, R;
Adamson, G;
... Fox, NC; + view all
(2016)
Clinical phenotype and genetic associations in autosomal dominant familial Alzheimer's disease: a case series.
LANCET NEUROLOGY
, 15
(13)
pp. 1326-1335.
10.1016/S1474-4422(16)30193-4.
|
|
|
Sammaraiee, Y;
Banerjee, G;
Farmer, S;
Hylton, B;
Cowley, P;
Eleftheriou, P;
Porter, J;
(2019)
Risks associated with oral deferiprone in the treatment of infratentorial superficial siderosis.
Journal of Neurology
, 267
, Article 682. 10.1007/s00415-019-09577-6.
|
|
Sampson, EL;
Anderson, J;
Candy, B;
Davies, N;
Ellis-Smith, C;
Gola, A;
Harding, R;
... Evans, CJ; + view all
(2020)
Empowering Better End‐of‐Life Dementia Care (EMBED‐Care): A mixed methods protocol to achieve integrated person‐centred care across settings.
International Journal of Geriatric Psychiatry
10.1002/gps.5251.
(In press).
|
|
|
Sandberg, MK;
Al-Doujaily, H;
Sharps, B;
De Oliveira, MW;
Schmidt, C;
Richard-Londt, A;
Lyall, S;
... Collinge, J; + view all
(2014)
Prion neuropathology follows the accumulation of alternate prion protein isoforms after infective titre has peaked.
Nat Commun
, 5
, Article 4347. 10.1038/ncomms5347.
|
|
|
Sangar, Daljit;
Hill, Elizabeth;
Jack, Kezia;
Batchelor, Mark;
Mistry, Beenaben;
Ribes, Juan M;
Jackson, Graham S;
... Bieschke, Jan; + view all
(2024)
Syntaxin-6 delays prion protein fibril formation and prolongs the presence of toxic aggregation intermediates.
eLife
, 13
, Article e83320. 10.7554/eLife.83320.
|
|
|
Santiago-Toledo, G;
Georgiou, M;
Dos Reis, J;
Roberton, VH;
Valinhas, A;
Wood, RC;
Phillips, JB;
... Wall, IB; + view all
(2019)
Generation of c-MycERTAM-transduced human late-adherent olfactory mucosa cells for potential regenerative applications.
Scientific Reports
, 9
(1)
, Article 13190. 10.1038/s41598-019-49315-6.
|
|
|
Sarell, CJ;
Quarterman, E;
Yip, DC-M;
Terry, C;
Nicoll, AJ;
Wadsworth, JDF;
Farrow, MA;
... Collinge, J; + view all
(2017)
Soluble Aβ aggregates can inhibit prion propagation.
Open Biology
, 7
(11)
, Article 170158. 10.1098/rsob.170158.
|
|
|
Sawyer, EB;
Edgeworth, JA;
Thomas, C;
Collinge, J;
Jackson, GS;
(2015)
Preclinical detection of infectivity and disease-specific PrP in blood throughout the incubation period of prion disease.
Scientific Reports
, 5
, Article 17742. 10.1038/srep17742.
|
|
|
Schmidt, C;
Fizet, J;
Properzi, F;
Batchelor, M;
Sandberg, MK;
Edgeworth, JA;
Afran, L;
... Collinge, J; + view all
(2015)
A systematic investigation of production of synthetic prions from recombinant prion protein.
Open Biology
, 5
(12)
, Article 150165. 10.1098/rsob.150165.
|
|
|
Schmidts, M;
Hou, Y;
Cortés, CR;
Mans, DA;
Huber, C;
Boldt, K;
Patel, M;
... Witman, GB; + view all
(2015)
TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport.
Nature Communications
, 6
, Article 7074. 10.1038/ncomms8074.
|
|
Schott, JM;
Crutch, SJ;
Carrasquillo, MM;
Uphill, J;
Shakespeare, TJ;
Ryan, NS;
Yong, KX;
... Mead, S; + view all
(2016)
Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease.
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
10.1016/j.jalz.2016.01.010.
|
|
|
Schwarz, G;
Banerjee, G;
Hostettler, IC;
Ambler, G;
Seiffge, DJ;
Ozkan, H;
Browning, S;
... Werring, DJ; + view all
(2022)
MRI and CT imaging biomarkers of cerebral amyloid angiopathy in lobar intracerebral hemorrhage.
International Journal of Stroke
10.1177/17474930211062478.
(In press).
|
|
|
Schweighauser, Manuel;
Arseni, Diana;
Bacioglu, Mehtap;
Huang, Melissa;
Lövestam, Sofia;
Shi, Yang;
Yang, Yang;
... Scheres, Sjors HW; + view all
(2022)
Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature
, 605
pp. 310-314.
10.1038/s41586-022-04650-z.
|
|
Seiffge, DJ;
Wilson, D;
Ambler, G;
Banerjee, G;
Hostettler, IC;
Houlden, H;
Shakeshaft, C;
... Werring, DJ; + view all
(2021)
Small vessel disease burden and intracerebral haemorrhage in patients taking oral anticoagulants.
Journal of Neurology, Neurosurgery & Psychiatry
10.1136/jnnp-2020-325299.
(In press).
|
|
|
Sequeira, Danielle;
Nihat, Akin;
Mok, Tzehow;
Coysh, Thomas;
Rudge, Peter;
Collinge, John;
Mead, Simon;
(2022)
Prevalence and Treatments of Movement Disorders in Prion Diseases: A Longitudinal Cohort Study.
Movement Disorders
10.1002/mds.29152.
(In press).
|
|
Sevcuka, Adriana;
White, Kenneth;
Terry, Cassandra;
(2022)
Factors That Contribute to hIAPP Amyloidosis in Type 2 Diabetes Mellitus.
Life
, 12
(4)
, Article 583. 10.3390/life12040583.
|
|
Shi, Y;
Zhang, W;
Yang, Y;
Murzin, AG;
Falcon, B;
Kotecha, A;
van Beers, M;
... Scheres, SHW; + view all
(2021)
Structure-based classification of tauopathies.
Nature
, 598
pp. 359-363.
10.1038/s41586-021-03911-7.
|
|
Shoemark, A;
Pinto, AL;
Patel, MP;
Daudvohra, F;
Hogg, C;
Mitchison, HM;
Burgoyne, T;
(2020)
PCD Detect: enhancing ciliary features through image averaging and classification.
American Journal of Physiology: Lung Cellular and Molecular Physiology
, 319
(6)
L1048-L1060.
10.1152/ajplung.00264.2020.
|
|
Shoemark, A;
Rubbo, B;
Legendre, M;
Fassad, MR;
Haarman, EG;
Best, S;
Bon, ICM;
... Lucas, JS; + view all
(2021)
Topological data analysis reveals genotype-phenotype relationships in primary ciliary dyskinesia.
European Respiratory Journal
, 58
(2)
, Article 2002359. 10.1183/13993003.02359-2020.
|
|
Shoemark, A;
Burgoyne, T;
Kwan, R;
Dixon, M;
Patel, MP;
Rogers, AV;
Onoufriadis, A;
... Hogg, C; + view all
(2018)
Primary ciliary dyskinesia with normal ultrastructure: three-dimensional tomography detects absence of DNAH11.
European Respiratory Journal
, 51
(2)
, Article 1701809. 10.1183/13993003.01809-2017.
|
|
Shoemark, A;
Frost, E;
Dixon, M;
Ollosson, S;
Kilpin, K;
Patel, M;
Scully, J;
... Hogg, C; + view all
(2017)
Accuracy of Immunofluorescence in the Diagnosis of Primary Ciliary Dyskinesia.
American Journal of Respiratory and Critical Care Medicine
, 196
(1)
pp. 94-101.
10.1164/rccm.201607-1351OC.
|
|
|
Simone, R;
Balendra, R;
Moens, TG;
Preza, E;
Wilson, KM;
Heslegrave, A;
Woodling, NS;
... Isaacs, AM; + view all
(2018)
G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo.
EMBO Molecular Medicine
, 10
(1)
pp. 22-31.
10.15252/emmm.201707850.
|
|
|
Sims, R;
van der Lee, SJ;
Naj, AC;
Bellenguez, C;
Badarinarayan, N;
Jakobsdottir, J;
Kunkle, BW;
... Schellenberg, GD; + view all
(2017)
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
Nature Genetics
, 49
pp. 1373-1384.
10.1038/ng.3916.
|
|
Sironen, A;
Shoemark, A;
Patel, M;
Loebinger, MR;
Mitchison, HM;
(2019)
Sperm defects in primary ciliary dyskinesia and related causes of male infertility.
Cellular and Molecular Life Sciences
10.1007/s00018-019-03389-7.
(In press).
|
|
|
Smethurst, P;
Risse, E;
Tyzack, GE;
Mitchell, JS;
Taha, DM;
Chen, Y-R;
Newcombe, J;
... Patani, R; + view all
(2020)
Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis.
Brain
, 143
(2)
pp. 430-440.
10.1093/brain/awz419.
|
|
|
Smith, Poppy O;
Huang, Guanbingxue;
Devries, Kate;
Nazhat, Showan N;
Phillips, James B;
(2024)
Automated production of nerve repair constructs containing endothelial cell tube-like structures.
Biofabrication
, 17
(1)
, Article 015024. 10.1088/1758-5090/ad8efd.
|
|
|
Spehar, K;
Ding, T;
Sun, Y;
Kedia, N;
Lu, J;
Nahass, G;
Lew, M;
(2018)
Super‐resolution Imaging of Amyloid Structures over Extended Times by Using Transient Binding of Single Thioflavin T Molecules.
ChemBioChem
, 19
(18)
pp. 1944-1948.
10.1002/cbic.201800352.
|
|
Stevens, JC;
Chia, R;
Hendriks, WT;
Bros-Facer, V;
van Minnen, J;
Martin, JE;
Jackson, GS;
... Fisher, EMC; + view all
(2010)
Modification of Superoxide Dismutase 1 (SOD1) Properties by a GFP Tag - Implications for Research into Amyotrophic Lateral Sclerosis (ALS).
PLOS ONE
, 5
(3)
, Article e9541. 10.1371/journal.pone.0009541.
|
|
|
Sudre, CH;
Bocchetta, M;
Cash, D;
Thomas, DL;
Woollacott, I;
Dick, KM;
van Swieten, J;
... Genetic FTD Initiative, GENFI, .; + view all
(2017)
White matter hyperintensities are seen only in GRN mutation carriers in the GENFI cohort.
NeuroImage: Clinical
, 15
pp. 171-180.
10.1016/j.nicl.2017.04.015.
|
|
Sudre, CH;
Bocchetta, M;
Heller, C;
Convery, R;
Neason, M;
Moore, KM;
Cash, DM;
... Rohrer, JD; + view all
(2019)
White matter hyperintensities in progranulin-associated frontotemporal dementia – a longitudinal GENFI study.
NeuroImage: Clinical
, Article 102077. 10.1016/j.nicl.2019.102077.
(In press).
|
|
|
Sun, Yuanzi;
Jack, Kezia;
Ercolani, Tiziana;
Sangar, Daljit;
Hosszu, Laszlo;
Collinge, John;
Bieschke, Jan;
(2023)
Direct Observation of Competing Prion Protein Fibril Populations with Distinct Structures and Kinetics.
ACS Nano
10.1021/acsnano.2c12009.
(In press).
|
|
Swarup, V;
Hinz, FI;
Rexach, JE;
Noguchi, K-I;
Toyoshiba, H;
Oda, A;
Hirai, K;
... Geschwind, DH; + view all
(2019)
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.
Nature Medicine
, 25
(1)
pp. 152-164.
10.1038/s41591-018-0223-3.
|
|
|
Taskesen, E;
Mishra, A;
Van Der Sluis, S;
Ferrari, R;
Veldink, JH;
Van Es, MA;
Smit, AB;
... Pijnenburg, Y; + view all
(2017)
Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS.
Scientific Reports
, 7
, Article 8899. 10.1038/s41598-017-09320-z.
|
|
Tattum, MH;
Jones, S;
Pal, S;
Collinge, J;
Jackson, GS;
(2010)
Discrimination between prion-infected and normal blood samples by protein misfolding cyclic amplification.
Transfusion
, 50
(5)
996 - 1002.
10.1111/j.1537-2995.2010.02595.x.
|
|
|
Tattum, MH;
Jones, S;
Pal, S;
Khalili-Shirazi, A;
Collinge, J;
Jackson, GS;
(2010)
A highly sensitive immunoassay for the detection of prion-infected material in whole human blood without the use of proteinase K.
Transfusion
, 50
(12)
2619 - 2627.
10.1111/j.1537-2995.2010.02731.x.
|
|
|
Taylor, GP;
Goon, P;
Furukawa, Y;
Green, H;
Barfield, A;
Mosley, A;
Nose, H;
... Weber, JN; + view all
(2006)
Zidovudine plus lamivudine in human T-lymphotropic virus type-I-associated myelopathy: a randomised trial.
Retrovirology
, 3
, Article 63. 10.1186/1742-4690-3-63.
|
|
|
Terry, C;
Harniman, RL;
Sells, J;
Wenborn, A;
Joiner, S;
Saibil, HR;
Miles, MJ;
... Wadsworth, JDF; + view all
(2019)
Structural features distinguishing infectious ex vivo mammalian prions from non-infectious fibrillar assemblies generated in vitro.
Scientific Reports
, 9
, Article 376. 10.1038/s41598-018-36700-w.
|
|
|
Terry, C;
Jiang, S;
Radford, DS;
Wan, Q;
Tzokov, S;
Moir, A;
Bullough, PA;
(2017)
Molecular tiling on the surface of a bacterial spore - the exosporium of the Bacillus anthracis/cereus/thuringiensis group.
Molecular Microbiology
, 104
(4)
pp. 539-552.
10.1111/mmi.13650.
|
|
Terry, C;
Wadsworth, JDF;
(2019)
Recent Advances in Understanding Mammalian Prion Structure: A Mini Review.
[Review].
Frontiers In Molecular Neuroscience
, 12
, Article 169. 10.3389/fnmol.2019.00169.
|
|
|
Terry, C;
Wenborn, A;
Gros, N;
Sells, J;
Joiner, S;
Hosszu, LL;
Tattum, MH;
... Wadsworth, JD; + view all
(2016)
Ex vivo mammalian prions are formed of paired double helical prion protein fibrils.
Open Biology
, 6
(5)
10.1098/rsob.160035.
|
|
|
Thaler, FS;
Koriath, C;
Vollmar, C;
Bardins, S;
Kremmyda, O;
Danek, A;
(2019)
Acute frontal eye field infarction: A topodiagnostic challenge.
Neurology
, 92
(4)
pp. 193-195.
10.1212/WNL.0000000000006813.
|
|
Thomas, DX;
Bajaj, S;
McRae-McKee, K;
Hadjichrysanthou, C;
Anderson, RM;
Collinge, J;
(2020)
Association ofTDP‑43
proteinopathy, cerebral
amyloid angiopathy, and Lewy
bodies with cognitive
impairment in individuals
with or withoutAlzheimer’s disease
neuropathology.
Scientific Reports
, 10
(1)
, Article 14579. 10.1038/s41598-020-71305-2.
|
|
|
Thompson, AG;
Uphill, J;
Lowe, J;
Porter, MC;
Lukic, A;
Carswell, C;
Rudge, P;
... Mead, S; + view all
(2015)
Genome-wide association study of behavioural and psychiatric features in human prion disease.
Transl Psychiatry
, 5
, Article e552. 10.1038/tp.2015.42.
|
|
|
Thompson, AGB;
Anastasiadis, P;
Druyeh, R;
Whitworth, I;
Nayak, A;
Nihat, A;
Mok, TH;
... Mead, S; + view all
(2021)
Evaluation of plasma tau and neurofilament light chain biomarkers in a 12-year clinical cohort of human prion diseases.
Molecular Psychiatry
10.1038/s41380-021-01045-w.
(In press).
|
|
|
Thompson, AGB;
Luk, C;
Heslegrave, AJ;
Zetterberg, H;
Mead, SH;
Collinge, J;
Jackson, GS;
(2018)
Neurofilament light chain and tau concentrations are markedly increased in the serum of patients with sporadic Creutzfeldt-Jakob disease, and tau correlates with rate of disease progression.
Journal of Neurology, Neurosurgery & Psychiatry
, 89
(9)
pp. 955-961.
10.1136/jnnp-2017-317793.
|
|
Thompson, AGB;
Mead, SH;
(2019)
Review: Fluid biomarkers in the human prion diseases.
Molecular and Cellular Neuroscience
, 97
pp. 81-92.
10.1016/j.mcn.2018.12.003.
|
|
Traeger, U;
Andre, R;
Lahiri, N;
Magnusson-Lind, A;
Weiss, A;
Grueninger, S;
McKinnon, C;
... Tabrizi, SJ; + view all
(2014)
HTT-lowering reverses Huntington's disease immune dysfunction caused by NF kappa B pathway dysregulation.
Brain
, 137
pp. 819-833.
10.1093/brain/awt355.
|
|
Trevitt, CR;
Hosszu, LL;
Batchelor, M;
Panico, S;
Terry, C;
Nicoll, AJ;
Risse, E;
... Clarke, AR; + view all
(2014)
N-terminal domain of prion protein directs its oligomeric association.
J Biol Chem
, 289
(37)
25497 - 25508.
10.1074/jbc.M114.566588.
|
|
|
Tsvetanov, KA;
Gazzina, S;
Jones, PS;
van Swieten, J;
Borroni, B;
Sanchez-Valle, R;
Moreno, F;
... Genetic FTD Initiative, GENFI; + view all
(2020)
Brain functional network integrity sustains cognitive function despite atrophy in presymptomatic genetic frontotemporal dementia.
Alzheimer's & Dementia
10.1002/alz.12209.
|
|
|
Ungureanu, AA;
Benilova, I;
Krylychkina, O;
Braeken, D;
De Strooper, B;
Van Haesendonck, C;
Dotti, CG;
(2016)
Amyloid beta oligomers induce neuronal elasticity changes in age-dependent manner: a force spectroscopy study on living hippocampal neurons.
Scientific Reports
, 6
, Article 25841. 10.1038/srep25841.
|
|
|
van der Lee, SJ;
Conway, OJ;
Jansen, I;
Carrasquillo, MM;
Kleineidam, L;
van den Akker, E;
Hernández, I;
... Holstege, H; + view all
(2020)
Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.
[Corrigendum].
Acta Neuropathologica
10.1007/s00401-019-02107-8.
(In press).
|
|
|
Varley, James A;
Andersson, Magnus;
Grant, Eleanor;
Berretta, Antonio;
Zandi, Michael S;
Bondet, Vincent;
Duffy, Darragh;
... Irani, Sarosh R; + view all
(2020)
Absence of Neuronal Autoantibodies in Neuropsychiatric Systemic Lupus Erythematosus.
Annals of Neurology
, 88
(6)
pp. 1244-1250.
10.1002/ana.25908.
|
|
Verzini, Silvia;
Shah, Maliha;
Theillet, Francois-Xavier;
Belsom, Adam;
Bieschke, Jan;
Wanker, Erich E;
Rappsilber, Juri;
... Selenko, Philipp; + view all
(2020)
Megadalton-sized Dityrosine Aggregates of α-Synuclein Retain High Degrees of Structural Disorder and Internal Dynamics.
Journal of Molecular Biology (JMB)
, 432
(24)
, Article 166689. 10.1016/j.jmb.2020.10.023.
|
|
Viré, EA;
Mead, S;
(2022)
Gene expression and epigenetic markers of prion diseases.
Cell and Tissue Research
10.1007/s00441-022-03603-2.
(In press).
|
|
|
Wadsworth, JDF;
Adamson, G;
Joiner, S;
Brock, L;
Powell, C;
Linehan, JM;
Beck, JA;
... Collinge, J; + view all
(2017)
Methods for Molecular Diagnosis of Human Prion Disease.
Methods in Molecular Biology: Prions
, 1658
pp. 311-346.
10.1007/978-1-4939-7244-9_22.
|
|
Wadsworth, JDF;
Joiner, S;
Linehan, JM;
Jack, K;
Al-Doujaily, H;
Costa, H;
Ingold, T;
... Collinge, J; + view all
(2021)
Humanised transgenic mice are resistant to chronic wasting disease prions from Norwegian reindeer and moose.
The Journal of Infectious Diseases
10.1093/infdis/jiab033.
(In press).
|
|
|
Wall, IB;
Toledo, GS;
Jat, PS;
(2016)
Recent advances in conditional cell immortalization technology.
Cell & Gene Therapy Insights
, 2
(3)
pp. 391-396.
10.18609/cgti.2016.041.
|
|
Wenborn, A;
Terry, C;
Gros, N;
Joiner, S;
D'Castro, L;
Panico, S;
Sells, J;
... Wadsworth, JD; + view all
(2015)
A novel and rapid method for obtaining high titre intact prion strains from mammalian brain.
Scientific Reports
, 5
, Article 10062. 10.1038/srep10062.
|
|
|
Weston, PSJ;
Poole, T;
O'Connor, A;
Heslegrave, A;
Ryan, NS;
Liang, Y;
Druyeh, R;
... Fox, NC; + view all
(2019)
Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimer's disease.
Alzheimer's Research & Therapy
, 11
, Article 19. 10.1186/s13195-019-0472-5.
|
|
|
Weston, PSJ;
Poole, T;
Ryan, NS;
Nair, A;
Liang, Y;
Macpherson, K;
Druyeh, R;
... Fox, NC; + view all
(2018)
Accelerated long-term forgetting in presymptomatic Autosomal Dominant Alzheimer's disease: A cross-sectional study.
Lancet Neurology
, 17
(2)
pp. 123-132.
10.1016/S1474-4422(17)30434-9.
|
|
|
Weston, PSJ;
Poole, T;
Ryan, NS;
Nair, A;
Liang, Y;
Macpherson, K;
Druyeh, R;
... Fox, NC; + view all
(2017)
Serum neurofilament light in familial Alzheimer disease: A marker of early neurodegeneration.
Neurology
, 89
(21)
pp. 2167-2175.
10.1212/WNL.0000000000004667.
|
|
Whitfield, Jerome T;
Pako, Wandagi H;
Alpers, Michael P;
(2024)
Robert Hertz, Anthropophagic Practices and Traditional South Fore Mortuary Rites in Papua New Guinea.
OMEGA - Journal of Death and Dying
10.1177/00302228241239210.
(In press).
|
|
Whitfield, JT;
Pako, WH;
Collinge, J;
Alpers, MP;
(2017)
Cultural factors that affected the spatial and temporal epidemiology of kuru.
ROYAL SOCIETY OPEN SCIENCE
, 4
, Article 160789. 10.1098/rsos.160789.
|
|
|
Wilke, C;
Reich, S;
van Swieten, JC;
Borroni, B;
Sanchez-Valle, R;
Moreno, F;
Laforce, R;
... Synofzik, M; + view all
(2021)
Stratifying the Presymptomatic Phase of Genetic Frontotemporal Dementia by Serum NfL and pNfH: A Longitudinal Multicentre Study.
Annals of Neurology
10.1002/ana.26265.
(In press).
|
|
Wilkins, Oscar G;
Chien, Max ZYJ;
Wlaschin, Josette J;
Barattucci, Simone;
Harley, Peter;
Mattedi, Francesca;
Mehta, Puja R;
... Fratta, Pietro; + view all
(2024)
Creation of de novo cryptic splicing for ALS and FTD precision medicine.
Science
, 386
(6717)
pp. 61-69.
10.1126/science.adk2539.
|
|
|
Willhoft, O;
Kerr, R;
Patel, D;
Zhang, W;
Al-Jassar, C;
Daviter, T;
Millson, SH;
... Vaughan, CK; + view all
(2017)
The crystal structure of the Sgt1-Skp1 complex: the link between Hsp90 and both SCF E3 ubiquitin ligases and kinetochores.
Scientific Reports
, 7
, Article 41626. 10.1038/srep41626.
|
|
|
Williams, Rachel;
Kantilal, Kumud;
Man, Kenneth KC;
Blandford, Ann;
Jani, Yogini;
(2025)
Barcode medication administration system use and safety implications: a data-driven longitudinal study supported by clinical observation.
BMJ Health Care Informatics
, 32
(1)
, Article e101214. 10.1136/bmjhci-2024-101214.
|
|
Wilson, D;
Ambler, G;
Banerjee, G;
Shakeshaft, C;
Cohen, H;
Yousry, TA;
Al-Shahi Salman, R;
... Werring, DJ; + view all
(2018)
Early versus late anticoagulation for ischaemic stroke associated with atrial fibrillation: multicentre cohort study.
Journal of Neurology, Neurosurgery & Psychiatry
, 90
(3)
pp. 320-325.
10.1136/jnnp-2018-318890.
|
|
Wilson, D;
Ambler, G;
Lee, K-J;
Lim, J-S;
Shiozawa, M;
Koga, M;
Li, L;
... Microbleeds International Collaborative Network, .; + view all
(2019)
Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies.
Lancet Neurology
10.1016/S1474-4422(19)30197-8.
(In press).
|
|
|
Wilson, D;
Ambler, G;
Shakeshaft, C;
Banerjee, G;
Charidimou, A;
Seiffge, D;
White, M;
... CROMIS-2 collaborators, .; + view all
(2019)
Potential missed opportunities to prevent ischaemic stroke: prospective multicentre cohort study of atrial fibrillation-associated ischaemic stroke and TIA.
BMJ Open
, 9
(7)
, Article e028387. 10.1136/bmjopen-2018-028387.
|
|
|
Wilson, D;
Ambler, G;
Shakeshaft, C;
Brown, MM;
Charidimou, A;
Salman, RA-S;
Lip, GYH;
... Werring, DJ; + view all
(2018)
Cerebral microbleeds and intracranial haemorrhage risk in patients anticoagulated for atrial fibrillation after acute ischaemic stroke or transient ischaemic attack (CROMIS-2): a multicentre observational cohort study.
The Lancet Neurology
, 17
(6)
pp. 539-547.
10.1016/S1474-4422(18)30145-5.
|
|
|
Wilson, D;
Chatterjee, F;
Farmer, SF;
Rudge, P;
McCarron, MO;
Cowley, P;
Werring, DJ;
(2017)
Infratentorial superficial siderosis: Classification, diagnostic criteria and rational investigation pathway.
Annals of Neurology
, 81
(3)
pp. 333-343.
10.1002/ana.24850.
|
|
Wilson, D;
Hostettler, IC;
Ambler, G;
Banerjee, G;
Jäger, HR;
Werring, DJ;
(2017)
Convexity subarachnoid haemorrhage has a high risk of intracerebral haemorrhage in suspected cerebral amyloid angiopathy.
Journal of Neurology
, 264
(4)
pp. 664-673.
10.1007/s00415-017-8398-y.
|
|
|
Wood-Kaczmar, A;
Gandhi, S;
Yao, Z;
Abramov, ASY;
Miljan, EA;
Keen, G;
Stanyer, L;
... Wood, NW; + view all
(2008)
PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons.
PLOS ONE
, 3
(6)
, Article e2455. 10.1371/journal.pone.0002455.
|
|
|
Yang, Yang;
Arseni, Diana;
Zhang, Wenjuan;
Huang, Melissa;
Lövestam, Sofia;
Schweighauser, Manuel;
Kotecha, Abhay;
... Goedert, Michel; + view all
(2022)
Cryo-EM structures of amyloid-β 42 filaments from human brains.
Science
, 375
(6577)
pp. 167-172.
10.1126/science.abm7285.
|
|
Yang, Yang;
Zhang, Wenjuan;
Murzin, Alexey G;
Schweighauser, Manuel;
Huang, Melissa;
Lovestam, Sofia;
Peak-Chew, Sew Y;
... Scheres, Sjors HW; + view all
(2023)
Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathologica
, 145
(3)
pp. 325-333.
10.1007/s00401-022-02533-1.
|
|
Young, AL;
Marinescu, RV;
Oxtoby, NP;
Bocchetta, M;
Yong, K;
Firth, NC;
Cash, DM;
... Alzheimer’s Disease Neuroimaging Initiative (ADNI), .; + view all
(2018)
Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference.
Nature Communications
, 9
, Article 4273. 10.1038/s41467-018-05892-0.
|
|
Zhang, Fuquan;
Joiner, Susan;
Linehan, Jacqueline M;
Pintilii, Florin;
Nazari, Tamsin;
Argentina, Fabio;
Preston, Connor;
... Wadsworth, Jonathan DF; + view all
(2025)
Isolation of a novel human prion strain from a PRNP codon 129 heterozygous vCJD patient.
PLoS Pathogens
, 21
(2)
, Article e1012904. 10.1371/journal.ppat.1012904.
|
|
|
Zhang, D;
Qi, Y;
Klyubin, I;
Ondrejcak, T;
Sarell, CJ;
Cuello, AC;
Collinge, J;
(2017)
Targeting glutamatergic and cellular prion protein mechanisms of amyloid β-mediated persistent synaptic plasticity disruption: longitudinal studies.
Neuropharmacology
, 121
pp. 231-246.
10.1016/j.neuropharm.2017.03.036.
|
|
Zhang, M;
Ferrari, R;
Tartaglia, MC;
Keith, J;
Surace, EI;
Wolf, U;
Sato, C;
... International FTD-Genomics Consortium (IFGC), .; + view all
(2018)
A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers.
Brain
, 141
(10)
pp. 2895-2907.
10.1093/brain/awy238.
|
|
|
Zhang, W;
Lukoynova, N;
Miah, S;
Lucas, J;
Vaughan, CK;
(2018)
Insights into Centromere DNA Bending Revealed by the Cryo-EM Structure of the Core Centromere Binding Factor 3 with Ndc10.
Cell Reports
, 24
(3)
pp. 744-754.
10.1016/j.celrep.2018.06.068.
|
|
Zhu, J;
Pittman, S;
Dhavale, D;
French, R;
Patterson, JN;
Kaleelurrrahuman, MS;
Sun, Y;
... Weihl, C; + view all
(2022)
VCP suppresses proteopathic seeding in neurons.
Molecular Neurodegeneration
, 17
, Article 30. 10.1186/s13024-022-00532-0.
|
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Ziff, OJ;
Banerjee, G;
Ambler, G;
Werring, DJ;
(2019)
Statins and the risk of intracerebral haemorrhage in patients with stroke: systematic review and meta-analysis.
Journal of Neurology, Neurosurgery, and Psychiatry
, 90
(1)
pp. 75-83.
10.1136/jnnp-2018-318483.
|
|
Book chapter
|
Manka, Szymon W;
(2023)
Mapping the Binding Sites of MMPs on Types II and III Collagens Using Triple-Helical Peptide Toolkits.
In: Santamaria, Salvatore, (ed.)
Proteases and Cancer: Methods and Protocols.
(pp. 75-82).
Humana (Springer): New York, NY, USA.
|
Proceedings paper
|
Canas, LS;
Yvernault, B;
Cash, DM;
Molteni, E;
Veale, T;
Benzinger, T;
Ourselin, S;
... Modat, M; + view all
(2018)
Gaussian processes with optimal kernel construction for neuro-degenerative clinical onset prediction.
In:
Proceedings Volume 10575, Medical Imaging 2018: Computer-Aided Diagnosis.
(pp. 105750G-1- 105750G-6).
SPIE: Houston, Texas, United States.
|
|
|
Canas, LS;
Yvernault, BC;
Sudre, CH;
Vita, ED;
Cardoso, MJ;
Thornton, JS;
Barkhof, F;
... Modat, M; + view all
(2018)
Imaging biomarkers for the diagnosis of Prion disease.
In: Angelini, ED and Landman, BA, (eds.)
Medical Imaging 2018: Image Processing.
(pp. p. 1057405).
SPIE: Houston, Texas, United States.
|
|
|
Ding, T;
Spehar, K;
Bieschke, J;
Lew, MD;
(2019)
Long-term, super-resolution imaging of amyloid structures using transient amyloid binding microscopy.
In:
Progress in Biomedical Optics and Imaging - Proceedings of SPIE.
SPIE: San Francisco, California, United States.
|
|
|
Spehar, K;
Ding, T;
Sun, Y;
Kedia, N;
Lu, J;
Nahass, GR;
Lew, MD;
(2019)
Long-term super-resolution imaging of amyloid structures using transient binding of Thioflavin T.
In:
Optical Molecular Probes, Imaging and Drug Delivery - Proceedings Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA, BRAIN, NTM, OMA, OMP).
OSA: Tucson, AZ, USA.
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Working / discussion paper
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Mole, J;
Mead, S;
Rudge, P;
Nihat, A;
Tzehow, M;
Collinge, J;
Caine, D;
(2020)
Cognitive decline heralds onset of symptomatic inherited prion disease.
MedRxiv: Cold Spring Harbor, NY, USA.
|
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|
Shi, Y;
Zhang, W;
Yang, Y;
Murzin, A;
Falcon, B;
Kotecha, A;
van Beers, M;
... Scheres, SHW; + view all
(2021)
Structure-based Classification of Tauopathies.
BioRxiv: Cold Spring Harbor, NY, USA.
|
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Conference item
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Rayner, M;
Healy, J;
Phillips, J;
(2017)
Investigating the effects of ibuprofen on axonal regeneration and functional recovery following peripheral nerve injury.
Presented at: 6th Vienna Symposium on Surgery of Peripheral Nerves, Vienna, Austria.
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Thesis
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Banerjee, Gargi;
(2019)
Clinical relevance of cerebral small vessel diseases in cognitive impairment, neurodegeneration and stroke.
Doctoral thesis (Ph.D), UCL (University College London).
|
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Begum, R;
(2013)
Functional analysis of Hectd2: a prion disease modifier associated with incubation time.
Doctoral thesis , UCL (University College London).
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Dabin, Luke Child;
(2019)
A profile of differential DNA methylation in sporadic human prion disease blood: precedent, implications and clinical promise.
Doctoral thesis (Ph.D), UCL (University College London).
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Dimitriadis, Athanasios;
(2022)
Transcriptomics of prion diseases.
Doctoral thesis (Ph.D), UCL (University College London).
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Halim, Hazim Arief Bin;
(2023)
The Mode of Prion Infection of Neuronal cells with extracellular PrP amyloids.
Doctoral thesis (Ph.D), UCL (University College London).
|
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Hill, Elizabeth Amy;
(2024)
The Role of Syntaxin-6 in Prion Diseases and Tauopathies.
Doctoral thesis (Ph.D), UCL (University College London).
|
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Jack, Kezia;
(2024)
What makes a prion a prion?
Investigating whether template structure or substrate identity
determines the formation of an infectious prion or a non-infectious
amyloid during in vitro aggregation.
Doctoral thesis (Ph.D), UCL (University College London).
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Koriath, Carolin Anna Maria;
(2020)
Next‐generation sequencing in the diagnosis of Dementia and Huntington’s disease Phenocopy Syndromes.
Doctoral thesis (Ph.D), UCL (University College London).
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Mistry, Beenaben Narendrakumar;
(2024)
Examining the Interactions of Amyloid-Beta and Tau with the Cellular Prion Protein.
Doctoral thesis (Ph.D), UCL (University College London).
|
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Mok, Tze How;
(2023)
Defining the onset of prion infection and neurodegeneration in healthy individuals at risk of prion disease.
Doctoral thesis (M.D(Res)), UCL (University College London).
|
|
Philiastides, Alexandra;
(2019)
Towards understanding selective neuronal vulnerability: establishing an in-vitro model for strain selection.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Porter, Marie-Claire Anne;
(2020)
The development of imaging biomarkers for the diagnosis of human prion disease.
Doctoral thesis (Ph.D), UCL (University College London).
|
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Ravey, J;
(2021)
Characterising microtubule-associated protein tau in clinical subtypes of pathologically defined Alzheimer’s disease.
Doctoral thesis (Ph.D), UCL (University College London).
|
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Rayner, Melissa Lucy Doreen;
(2019)
Investigating small molecule therapeutics to improve regeneration and functional recovery following peripheral nerve damage.
Doctoral thesis (Ph.D), UCL (University College London).
|
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Reilly, Madeleine Louise;
(2019)
Development of an in vitro assay of prion-induced neurotoxicity.
Doctoral thesis (Ph.D), UCL (University College London).
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Shiltagh, N;
(2013)
Solution structure of the factor VIII binding region on von Willebrand factor.
Doctoral thesis , UCL (University College London).
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Sun, Yuanzi;
(2022)
Single-particle Kinetic Measurements and Structure Characterization of PrP Fibril Elongation Using Super-Resolution Microscopy.
Doctoral thesis (Ph.D), UCL (University College London).
|
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Thomas, David Mark Xavier;
(2019)
Investigating the biochemical signature and in vivo seeding activity of amyloid-β from distinct Alzheimer’s Disease subtypes.
Doctoral thesis (Ph.D), UCL (University College London).
|
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Turnbull, Catherine Mary;
(2024)
Characterising tau morphotypes within different subtypes of Alzheimer’s disease (AD) and their transmission in AD mouse models.
Doctoral thesis (Ph.D), UCL (University College London).
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