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Detection of Creutzfeldt-Jakob disease prions in skin: implications for healthcare.

Nihat, A; Mead, S; (2018) Detection of Creutzfeldt-Jakob disease prions in skin: implications for healthcare. Genome Medicine , 10 (1) , Article 22. 10.1186/s13073-018-0536-3. Green open access

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Abstract

Evidence has recently been reported of prion seeding activity in skin tissue from patients with sporadic Creutzfeldt-Jakob disease (sCJD). This is relevant information for infection control measures during surgery. The work uses very sensitive prion assays now available for medical research, and may soon be adapted to related neurodegenerative disorders.

Type: Article
Title: Detection of Creutzfeldt-Jakob disease prions in skin: implications for healthcare.
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1186/s13073-018-0536-3
Publisher version: http://dx.doi.org/10.1186/s13073-018-0536-3
Language: English
Additional information: © The Author(s). 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Institute of Prion Diseases
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Institute of Prion Diseases > MRC Prion Unit at UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Institute of Prion Diseases > UCL Institute of Prion Diseases Support
URI: https://discovery.ucl.ac.uk/id/eprint/10046723
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