Spehar, K;
Ding, T;
Sun, Y;
Kedia, N;
Lu, J;
Nahass, GR;
Lew, MD;
(2019)
Long-term super-resolution imaging of amyloid structures using transient binding of Thioflavin T.
In:
Optical Molecular Probes, Imaging and Drug Delivery - Proceedings Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA, BRAIN, NTM, OMA, OMP).
OSA: Tucson, AZ, USA.
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Abstract
Amyloids are implicated in Alzheimer’s disease but cannot be well resolved by standard light microscopy. We developed a tool to directly image native amyloid structures and dynamics at nanometer resolution over minutes to days.
| Type: | Proceedings paper |
|---|---|
| Title: | Long-term super-resolution imaging of amyloid structures using transient binding of Thioflavin T |
| Event: | Optical Molecular Probes, Imaging and Drug Delivery 2019 |
| ISBN-13: | 9781943580545 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1364/OMP.2019.OW4D.4 |
| Publisher version: | https://doi.org/10.1364/OMP.2019.OW4D.4 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Institute of Prion Diseases UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Institute of Prion Diseases > MRC Prion Unit at UCL |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10102866 |
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