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Article

Abbosh, C; Swanton, C; (2021) ctDNA: An emerging neoadjuvant biomarker in resectable solid tumors. PLoS Medicine , 18 (10) , Article e1003771. 10.1371/journal.pmed.1003771. Green open access
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Abdul-Jawad, S; Baù, L; Alaguthurai, T; Del Molino Del Barrio, I; Laing, AG; Hayday, TS; Monin, L; ... Irshad, S; + view all (2021) Acute immune signatures and their legacies in severe acute respiratory syndrome coronavirus-2 infected cancer patients. Cancer Cell 10.1016/j.ccell.2021.01.001. (In press). Green open access
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Adams, RA; Fisher, DJ; Graham, J; Seligmann, JF; Seymour, M; Kaplan, R; Yates, E; ... FOCUS4 Trial Investigators; + view all (2021) Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial. Journal of clinical oncology: official journal of the American Society of Clinical Oncology 10.1200/JCO.21.01436. (In press). Green open access
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Ahmed, Mahbubl; Collins, Shane; Bacon, Andrew; Franks, Joanna; Lobo, Cheryl; Paley, Lizz; Strauss, Sandra; (2021) 08. Incidence and outcome of breast sarcomas in NHS England (2013-2018): An analysis from Public Health England (PHE) National Cancer Registration and Analysis Service (NCRAS). European Journal of Surgical Oncology , 47 (5) e288-e288. 10.1016/j.ejso.2021.03.204. Green open access
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Akay, M; Funingana, I-G; Patel, G; Mustapha, R; Gjafa, E; Ng, T; Ng, K; (2021) An In-Depth Review of Niraparib in Ovarian Cancer: Mechanism of Action, Clinical Efficacy and Future Directions. Oncology and Therapy 10.1007/s40487-021-00167-z. (In press). Green open access
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Ali, A; Hoyle, AP; Parker, CC; Brawley, CD; Cook, A; Amos, C; Calvert, J; ... STAMPEDE investigators; + view all (2021) Bone metastatic burden as a predictor of survival benefit from prostate radiotherapy in newly-diagnosed metastatic prostate cancer. JAMA oncology , 7 (4) pp. 555-563. 10.1001/jamaoncol.2020.7857. Green open access
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Alliouachene, S; Kieswich, JE; Bilanges, B; McCafferty, K; Thiemermann, C; Vanhaesebroeck, B; Yaqoob, MM; (2021) Uninephrectomy and class II PI3K-C2β inactivation synergistically protect against obesity, insulin resistance and liver steatosis in mice. American Journal of Transplantation 10.1111/ajt.16470. (In press). Green open access
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Anquetil, T; Solinhac, R; Jaffre, A; Chicanne, G; Viaud, J; Darcourt, J; Orset, C; ... Gratacap, M-P; + view all (2021) PI3KC2β inactivation stabilizes VE-cadherin junctions and preserves vascular integrity. EMBO Reports , 22 (6) , Article e51299. 10.15252/embr.202051299. Green open access
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Arshad, R; Tabish, TA; Kiani, MH; Ibrahim, IM; Shahnaz, G; Rahdar, A; Kang, M; (2021) A Hyaluronic Acid Functionalized Self-Nano-Emulsifying Drug Delivery System (SNEDDS) for Enhancement in Ciprofloxacin Targeted Delivery against Intracellular Infection. Nanomaterials , 11 (5) , Article 1086. 10.3390/nano11051086. Green open access
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Attard, G; Brown, LC; Clarke, NW; Parmar, MKB; James, ND; (2021) Should Patients with High-risk Localised or Locally Advanced Prostate Cancer Receive Abiraterone Acetate in Addition to Androgen Deprivation Therapy? Update on a Planned Analysis of the STAMPEDE Trial. European Urology , 80 (4) pp. 522-523. 10.1016/j.eururo.2021.06.023. Green open access
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Attard, G; Murphy, L; Clarke, NW; Cross, W; Jones, RJ; Parker, CC; Gillessen, S; ... Systemic Therapy in Advancing or Metastatic Prostate cancer: Eva; + view all (2021) Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol. The Lancet 10.1016/S0140-6736(21)02437-5. (In press). Green open access
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Au, L; Hatipoglu, E; Robert de Massy, M; Litchfield, K; Beattie, G; Rowan, A; Schnidrig, D; ... TRACERx Renal Consortium; + view all (2021) Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma. Cancer Cell , 39 pp. 1497-1518. 10.1016/j.ccell.2021.10.001. Green open access
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Au, L; Fendler, A; Shepherd, STC; Rzeniewicz, K; Cerrone, M; Byrne, F; Carlyle, E; ... Turajlic, S; + view all (2021) Cytokine release syndrome in a patient with colorectal cancer after vaccination with BNT162b2. Nature Medicine 10.1038/s41591-021-01387-6. Green open access
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Bailey, C; Black, JRM; Reading, JL; Litchfield, K; Turajlic, S; McGranahan, N; Jamal-Hanjani, M; (2021) Tracking Cancer Evolution through the Disease Course. Cancer Discovery , 11 (4) pp. 916-932. 10.1158/2159-8290.CD-20-1559. Green open access
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Balestrini, S; Koepp, MJ; Gandhi, S; Rickman, HM; Yen Shin, G; Houlihan, CF; Anders-Cannon, J; ... Sisodiya, SM; + view all (2021) Clinical outcomes of COVID-19 in long-term care facilities for people with epilepsy. Epilepsy & Behavior , 115 , Article 107602. 10.1016/j.yebeh.2020.107602. Green open access
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Banfill, K; Croxford, W; Fornacon-Wood, I; Wicks, K; Ahmad, S; Britten, A; Carson, C; ... Faivre-Finn, C; + view all (2021) Changes in the Management of Patients having Radical Radiotherapy for Lung Cancer during the First Wave of the COVID-19 Pandemic in the UK. Clinical Oncology 10.1016/j.clon.2021.10.009. (In press). Green open access
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Bartlett, JMS; Bayani, J; Kornaga, E; Xu, K; Pond, GR; Piper, T; Mallon, E; ... Rea, D; + view all (2021) Comparative survival analysis of multiparametric tests-when molecular tests disagree-A TEAM Pathology study. NPJ Breast Cancer , 7 (1) , Article 90. 10.1038/s41523-021-00297-7. Green open access
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Bentham, R; Litchfield, K; Watkins, TBK; Lim, EL; Rosenthal, R; Martinez-Ruiz, C; Hiley, CT; ... McGranahan, N; + view all (2021) Using DNA sequencing data to quantify T cell fraction and therapy response. Nature , 597 pp. 555-560. 10.1038/s41586-021-03894-5. Green open access
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Bertaglia, V; Reale, ML; Bironzo, P; Palesandro, E; Mariniello, A; Leone, G; Tabbò, F; ... Novello, S; + view all (2021) Italian survey on the clinical management of non-small cell lung cancer patients during the COVID-19 pandemic: A lesson for the second wave. Critical Reviews in Oncology/Hematology , 157 , Article 103189. 10.1016/j.critrevonc.2020.103189. Green open access
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Best, J; Starkey, T; Chaterjee, A; Fackrell, D; Pettit, L; Srihari, N; Tween, H; ... Lee, LYW; + view all (2021) Coronavirus Disease 2019: the Pivotal Role of UK Clinical Oncology and the UK Coronavirus Cancer Monitoring Project. Clinical Oncology , 33 (1) e50-e53. 10.1016/j.clon.2020.05.021. Green open access
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Black, JRM; McGranahan, N; (2021) Genetic and non-genetic clonal diversity in cancer evolution. Nature Reviews Cancer , 21 (6) pp. 379-392. 10.1038/s41568-021-00336-2. Green open access
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Bofinger, R; Weitsman, G; Evans, R; Glaser, M; Sander, K; Allan, H; Hochhauser, D; ... Tabor, AB; + view all (2021) Drug delivery, biodistribution and anti-EGFR activity: theragnostic nanoparticles for simultaneous in vivo delivery of tyrosine kinase inhibitors and kinase activity biosensors. Nanoscale 10.1039/d1nr02770k. (In press). Green open access
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Booth, S; Curley, HM; Varnai, C; Arnold, R; Lee, LYW; Campton, NA; Cook, G; ... Palles, C; + view all (2021) Key findings from the UKCCMP cohort of 877 patients with haematological malignancy and COVID-19: disease control as an important factor relative to recent chemotherapy or anti-CD20 therapy. British Journal of Haematology 10.1111/bjh.17937. (In press). Green open access
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Bortolomeazzi, M; Keddar, MR; Montorsi, L; Acha-Sagredo, A; Benedetti, L; Temelkovski, D; Choi, S; ... Ciccarelli, FD; + view all (2021) Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts. Gastroenterology 10.1053/j.gastro.2021.06.064. (In press). Green open access
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Brooks, LJ; Clements, MP; Burden, JJ; Kocher, D; Richards, L; Devesa, SC; Zakka, L; ... Parrinello, S; + view all (2021) The white matter is a pro-differentiative niche for glioblastoma. Nature Communications , 12 , Article 2184. 10.1038/s41467-021-22225-w. Green open access
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Buck, M; Poirier, E; Cardoso, A; Frederico, B; Canton, J; Barrell, S; Beale, R; ... The Crick COVID-19 Consortium; + view all (2021) SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay [version 1; peer review: 1 approved with reservations]. Wellcome Open Research , 6 (9) 10.12688/wellcomeopenres.16517.1. Green open access
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Buck, MD; Poirier, EZ; Cardoso, A; Frederico, B; Canton, J; Barrell, S; Beale, R; ... Crick COVID-19 Consortium; + view all (2021) SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay. Wellcome Open Research , 6 , Article 9. 10.12688/wellcomeopenres.16517.2. Green open access
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Busacca, S; Zhang, Q; Sharkey, A; Dawson, AG; Moore, DA; Waller, DA; Nakas, A; ... Fennell, DA; + view all (2021) Transcriptional perturbation of protein arginine methyltransferase-5 exhibits MTAP-selective oncosuppression. Scientific Reports , 11 (1) , Article 7434. 10.1038/s41598-021-86834-7. Green open access
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Byers, LA; Navarro, A; Schaefer, E; Johnson, M; Özgüroğlu, M; Han, J-Y; Bondarenko, I; ... Forster, M; + view all (2021) A Phase II Trial of Prexasertib (LY2606368) in Patients With Extensive-Stage Small-Cell Lung Cancer. Clinical Lung Cancer , 22 (6) pp. 531-540. 10.1016/j.cllc.2021.04.005. Green open access
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Cabrera, R; Singal, AG; Colombo, M; Kelley, RK; Lee, H; Mospan, AR; Meyer, T; ... Di Bisceglie, AM; + view all (2021) A Real-World Observational Cohort of Patients with Hepatocellular Carcinoma: Design and Rationale for TARGET-HCC. Hepatology Communications , 5 (3) pp. 538-547. 10.1002/hep4.1652. Green open access
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Cai, H; Chew, SK; Li, C; Tsai, MK; Andrejka, L; Murray, CW; Hughes, NW; ... Winslow, MM; + view all (2021) A Functional Taxonomy of Tumor Suppression in Oncogenic KRAS-Driven Lung Cancer. Cancer Discovery , 11 (7) pp. 1754-1773. 10.1158/2159-8290.CD-20-1325. Green open access
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Carter, TJ; Agliardi, G; Lin, F-Y; Ellis, M; Jones, C; Robson, M; Richard-Londt, A; ... Chester, K; + view all (2021) Potential of Magnetic Hyperthermia to Stimulate Localized Immune Activation. Small , Article e2005241. 10.1002/smll.202005241. (In press). Green open access
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Chambers, P; Wei, L; Forster, MD; Kipps, E; Wong, ICK; Jani, Y; (2021) Evidence to guide the optimal timing for pre-chemotherapy blood tests for early breast, colorectal cancer and diffuse large B-cell lymphoma. Cancer Medicine 10.1002/cam4.4316. (In press). Green open access
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Chen, M; Chen, R; Jin, Y; Li, J; Hu, X; Zhang, J; Fujimoto, J; ... Zhang, J; + view all (2021) Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer. Nature Communications , 12 , Article 6655. 10.1038/s41467-021-26821-8. Green open access
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Chen, X; Zhabyeyev, P; Azad, AK; Vanhaesebroeck, B; Grueter, CE; Murray, AG; Kassiri, Z; (2021) Pharmacological and cell-specific genetic PI3Kα inhibition worsens cardiac remodeling after myocardial infarction. Journal of Molecular and Cellular Cardiology , 157 pp. 17-30. 10.1016/j.yjmcc.2021.04.004. Green open access
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Chen, S-H; Miles, K; Taylor, SA; Ganeshan, B; Rodriquez, M; Fraioli, F; Wan, S; ... Groves, A; + view all (2021) FDG-PET/CT in colorectal cancer: potential for vascular-metabolic imaging to provide markers of prognosis. European Journal of Nuclear Medicine and Molecular Imaging 10.1007/s00259-021-05318-y. (In press). Green open access
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Childs, A; Zakeri, N; Ma, YT; O’Rourke, J; Ross, P; Hashem, E; Hubner, RA; ... Meyer, T; + view all (2021) Biopsy for advanced hepatocellular carcinoma: results of a multicentre UK audit. British Journal of Cancer 10.1038/s41416-021-01535-2. (In press). Green open access
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Childs, A; Steele, CD; Vesely, C; Rizzo, FMM; Ensell, L; Lowe, H; Dhami, P; ... Meyer, T; + view all (2021) Whole genome sequencing of single circulating tumor cells from neuroendocrine neoplasms. Endocrine-Related Cancer 10.1530/ERC-21-0179. (In press). Green open access
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Chung, C-Y; Singh, K; Kotiadis, VN; Valdebenito, GE; Ahn, JH; Topley, E; Tan, J; ... Duchen, MR; + view all (2021) Constitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243 A > G mtDNA mutation. Nature Communications , 12 (1) , Article 6409. 10.1038/s41467-021-26746-2. Green open access
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Collier, DA; De Marco, A; Ferreira, IATM; Meng, B; Datir, RP; Walls, AC; Kemp, SA; ... Gupta, RK; + view all (2021) Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies. Nature , 593 pp. 136-141. 10.1038/s41586-021-03412-7. Green open access
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Conforti, F; Pala, L; Pagan, E; Bagnardi, V; De Pas, T; Queirolo, P; Pennacchioli, E; ... Giaccone, G; + view all (2021) Sex-Based Dimorphism of Anticancer Immune Response and Molecular Mechanisms of Immune Evasion. Clinical Cancer Research , 27 (15) pp. 4311-4324. 10.1158/1078-0432.CCR-21-0136. Green open access
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Cortellini, A; De Giglio, A; Cannita, K; Cortinovis, DL; Cornelissen, R; Baldessari, C; Giusti, R; ... Porzio, G; + view all (2021) Smoking status during first-line immunotherapy and chemotherapy in NSCLC patients: A case–control matched analysis from a large multicenter study. Thoracic Cancer , 12 (6) pp. 880-889. 10.1111/1759-7714.13852. Green open access
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de Silva, TI; Liu, G; Lindsey, BB; Dong, D; Moore, SC; Hsu, NS; Shah, D; ... Dong, T; + view all (2021) The impact of viral mutations on recognition by SARS-CoV-2 specific T cells. iScience , 24 (11) , Article 103353. 10.1016/j.isci.2021.103353. Green open access
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Dejima, Hitoshi; Hu, Xin; Chen, Runzhe; Zhang, Jiexin; Fujimoto, Junya; Parra, Edwin R; Haymaker, Cara; ... Zhang, Jianjun; + view all (2021) Immune evolution from preneoplasia to invasive lung adenocarcinomas and underlying molecular features. Nature Communications , 12 (1) , Article 2722. 10.1038/s41467-021-22890-x. Green open access
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Dentro, SC; Leshchiner, I; Haase, K; Tarabichi, M; Wintersinger, J; Deshwar, AG; Yu, K; ... PCAWG Evolution and Heterogeneity Working Group and the PCAWG Co, .; + view all (2021) Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes. Cell , 184 (8) pp. 2239-2254. 10.1016/j.cell.2021.03.009. Green open access
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Dettorre, GM; Dolly, S; Loizidou, A; Chester, J; Jackson, A; Mukherjee, U; Zambelli, A; ... OnCovid study group; + view all (2021) Systemic pro-inflammatory response identifies patients with cancer with adverse outcomes from SARS-CoV-2 infection: the OnCovid Inflammatory Score. Journal for ImmunoTherapy of Cancer , 9 (3) , Article e002277. 10.1136/jitc-2020-002277. Green open access
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Ding, H; Velasco, C; Ye, H; Lindner, T; Grech-Sollars, M; O'Callaghan, J; Hiley, C; ... Adeleke, S; + view all (2021) Current Applications and Future Development of Magnetic Resonance Fingerprinting in Diagnosis, Characterization, and Response Monitoring in Cancer. Cancers , 13 (19) , Article 4742. 10.3390/cancers13194742. Green open access
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Dujon, Antoine M; Aktipis, Athena; Alix-Panabieres, Catherine; Amend, Sarah R; Boddy, Amy M; Brown, Joel S; Capp, Jean-Pascal; ... Ujvari, Beata; + view all (2021) Identifying key questions in the ecology and evolution of cancer. Evolutionary Applications , 14 (4) pp. 877-892. 10.1111/eva.13190. Green open access
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El Bairi, K; Haynes, HR; Blackley, E; Fineberg, S; Shear, J; Turner, S; de Freitas, JR; ... Bautista, V; + view all (2021) The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group. npj Breast Cancer , 7 , Article 150. 10.1038/s41523-021-00346-1. Green open access
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Emanuel, O; Liu, J; Schartinger, VH; Nei, WL; Chan, YY; Tsang, CM; Riechelmann, H; ... Lechner, M; + view all (2021) SSTR2 in Nasopharyngeal Carcinoma: Relationship with Latent EBV Infection and Potential as a Therapeutic Target. Cancers , 13 (19) , Article 4944. 10.3390/cancers13194944. Green open access
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Evison, M; Barrett, E; Cheng, A; Mulla, A; Walls, G; Johnston, D; McAleese, J; ... Faivre-Finn, C; + view all (2021) Predicting the Risk of Disease Recurrence and Death Following Curative-intent Radiotherapy for Non-small Cell Lung Cancer: The Development and Validation of Two Scoring Systems From a Large Multicentre UK Cohort. Clinical Oncology , 33 (3) pp. 145-154. 10.1016/j.clon.2020.09.001. Green open access
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Fendler, A; Au, L; Shepherd, STC; Byrne, F; Cerrone, M; Boos, LA; Rzeniewicz, K; ... Wilkinson, RJ; + view all (2021) Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study. Nature Cancer 10.1038/s43018-021-00275-9. (In press). Green open access
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Fendler, A; Shepherd, STC; Au, L; Wilkinson, KA; Wu, M; Byrne, F; Cerrone, M; ... Turajlic, S; + view all (2021) Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study. Nature Cancer 10.1038/s43018-021-00274-w. (In press). Green open access
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Feng, FY; Huang, H-C; Spratt, DE; Zhao, SG; Sandler, HM; Simko, JP; Davicioni, E; ... Tran, PT; + view all (2021) Validation of a 22-Gene Genomic Classifier in Patients With Recurrent Prostate Cancer An Ancillary Study of the NRG/RTOG 9601 Randomized Clinical Trial. JAMA Oncology , 7 (4) pp. 544-552. 10.1001/jamaoncol.2020.7671. Green open access
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Fu, X; Zhao, Y; Lopez, JI; Rowan, A; Au, L; Fendler, A; Hazell, S; ... Bates, PA; + view all (2021) Spatial patterns of tumour growth impact clonal diversification in a computational model and the TRACERx Renal study. Nature Ecology & Evolution 10.1038/s41559-021-01586-x. Green open access
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Ganeshan, B; Miles, K; Afaq, A; Punwani, S; Rodriguez, M; Wan, S; Walls, D; ... Groves, A; + view all (2021) Texture Analysis of Fractional Water Content Images Acquired during PET/MRI: Initial Evidence for an Association with Total Lesion Glycolysis, Survival and Gene Mutation Profile in Primary Colorectal Cancer. Cancers , 13 (11) , Article 2715. 10.3390/cancers13112715. Green open access
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Garrigós, L; Saura, C; Martinez-Vila, C; Zambelli, A; Bower, M; Pistilli, B; Lambertini, M; ... Gennari, A; + view all (2021) COVID-19 in breast cancer patients: a subanalysis of the OnCovid registry. Therapeutic Advances in Medical Oncology , 13 pp. 1-11. 10.1177/17588359211053416. Green open access
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Gaspar, N; Campbell-Hewson, Q; Gallego Melcon, S; Locatelli, F; Venkatramani, R; Hecker-Nolting, S; Gambart, M; ... Casanova, M; + view all (2021) Phase I/II study of single-agent lenvatinib in children and adolescents with refractory or relapsed solid malignancies and young adults with osteosarcoma (ITCC-050). ESMO Open , 6 (5) , Article 100250. 10.1016/j.esmoop.2021.100250. Green open access
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Gaspar, N; Venkatramani, R; Hecker-Nolting, S; Melcon, SG; Locatelli, F; Bautista, F; Longhi, A; ... Campbell-Hewson, Q; + view all (2021) Lenvatinib with etoposide plus ifosfamide in patients with refractory or relapsed osteosarcoma (ITCC-050): a multicentre, open-label, multicohort, phase 1/2 study. Lancet Oncology , 22 (9) pp. 1312-1321. 10.1016/S1470-2045(21)00387-9. Green open access
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Glosli, H; Bisogno, G; Kelsey, A; Chisholm, JC; Gaze, M; Kolb, F; McHugh, K; ... Orbach, D; + view all (2021) Non-parameningeal head and neck rhabdomyosarcoma in children, adolescents, and young adults: Experience of the European paediatric Soft tissue sarcoma Study Group (EpSSG) – RMS2005 study. European Journal of Cancer , 151 pp. 84-93. 10.1016/j.ejca.2021.04.007. Green open access
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Goyal, L; Kongpetch, S; Crolley, VE; Bridgewater, J; (2021) Targeting FGFR inhibition in cholangiocarcinoma. Cancer Treatment Reviews , 95 , Article 102170. 10.1016/j.ctrv.2021.102170. Green open access
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Graham, MS; Sudre, CH; May, A; Antonelli, M; Murray, B; Varsaysky, T; Klaser, K; ... Ourselin, S; + view all (2021) Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study. Lancet Public Health , 6 (5) E335-E345. 10.1016/S2468-2667(21)00055-4. Green open access
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Green, S; Tuck, S; Long, J; Green, T; Green, A; Ellis, P; Haire, A; ... Van Hemelrijck, M; + view all (2021) ReIMAGINE: a prostate cancer research consortium with added value through its patient and public involvement and engagement. Research Involvement and Engagement , 7 (1) , Article 81. 10.1186/s40900-021-00322-w. Green open access
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Gronchi, A; Miah, AB; DeiTos, AP; Abecassis, N; Bajpai, J; Bauer, S; Biagini, R; ... Stacchiotti, S; + view all (2021) Soft tissue and visceral sarcomas: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology , 32 (11) pp. 1348-1365. 10.1016/j.annonc.2021.07.006. Green open access
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Gundogdu, R; Erdogan, MK; Ditsiou, A; Spanswick, V; Garcia-Gomez, JJ; Hartley, JA; Esashi, F; ... Gomez, V; + view all (2021) hMOB2 deficiency impairs homologous recombination-mediated DNA repair and sensitises cancer cells to PARP inhibitors. Cellular Signalling , 87 , Article 110106. 10.1016/j.cellsig.2021.110106. Green open access
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Guo, C; Crespo, M; Gurel, B; Dolling, D; Rekowski, J; Sharp, A; Petremolo, A; ... International SU2C PCF Prostate Cancer Dream Team, .; + view all (2021) CD38 in Advanced Prostate Cancers. European Urology , 79 (6) pp. 736-746. 10.1016/j.eururo.2021.01.017. Green open access
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Hamid, AA; Huang, H-C; Wang, V; Chen, Y-H; Feng, F; Den, R; Attard, G; ... Sweeney, CJ; + view all (2021) Transcriptional profiling of primary prostate tumor in metastatic hormone-sensitive prostate cancer and association with clinical outcomes: correlative analysis of the E3805 CHAARTED trial. Annals of Oncology , 32 (9) pp. 1157-1166. 10.1016/j.annonc.2021.06.003. Green open access
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Han, G; Yang, G; Hao, D; Lu, Y; Thein, K; Simpson, BS; Chen, J; ... Wang, L; + view all (2021) 9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapy. Nature Communications , 12 , Article 5606. 10.1038/s41467-021-25894-9. Green open access
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Hartley, JA; (2021) Antibody-drug conjugates (ADCs) delivering pyrrolobenzodiazepine (PBD) dimers for cancer therapy. Expert Opinion on Biological Therapy , 21 (7) pp. 931-943. 10.1080/14712598.2020.1776255. Green open access
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Hayes, AR; Mak, IYF; Evans, N; Naik, R; Crawford, A; Khoo, B; Grossman, AB; ... Meyer, T; + view all (2021) Understanding the Treatment Algorithm of Patients with Metastatic Pancreatic Neuroendocrine Neoplasms: A Single-Institution Retrospective Analysis Comparing Outcomes of Chemotherapy, Molecular Targeted Therapy, and Peptide Receptor Radionuclide Therapy in 255 Patients. Neuroendocrinology , 111 (9) pp. 863-875. 10.1159/000511662. Green open access
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Hellewell, J; Russell, TW; SAFER Investigators and Field Study Team, ,; Crick COVID-19 Consortium, ,; CMMID COVID-19 working group, ,; Beale, R; Kelly, G; ... Kucharski, AJ; + view all (2021) Estimating the effectiveness of routine asymptomatic PCR testing at different frequencies for the detection of SARS-CoV-2 infections. BMC Medicine , 19 (1) , Article 106. 10.1186/s12916-021-01982-x. Green open access
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Hernando, B; Dietzen, M; Parra, G; Gil-Barrachina, M; Pitarch, G; Mahiques, L; Valcuende-Cavero, F; ... Martinez-Cadenas, C; + view all (2021) The effect of age on the acquisition and selection of cancer driver mutations in sun-exposed normal skin. Annals of Oncology , 32 (3) pp. 412-421. 10.1016/j.annonc.2020.11.023. Green open access
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Hofmann, MR; Hussain, M; Dehm, SM; Beltran, H; Wyatt, AW; Halabi, S; Sweeney, C; ... Sharifi, N; + view all (2021) Prostate Cancer Foundation Hormone-Sensitive Prostate Cancer Biomarker Working Group Meeting Summary. Urology , 155 pp. 165-171. 10.1016/j.urology.2020.12.021. Green open access
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Hu, Xin; Estecio, Marcos R; Chen, Runzhe; Reuben, Alexandre; Wang, Linghua; Fujimoto, Junya; Carrot-Zhang, Jian; ... Zhang, Jianjun; + view all (2021) Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas. Nature Communications , 12 , Article 687. 10.1038/s41467-021-20907-z. Green open access
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Satish, P; Simpson, B; Freeman, A; Giganti, F; Kirkham, A; Orczyk, C; Whitaker, H; ... Norris, JM; + view all (2021) Mapping Contemporary Biopsy Zones to Traditional Prostatic Anatomy: The Key to Understanding Relationships Between Prostate Cancer Topography, Magnetic Resonance Imaging Conspicuity, and Clinical Risk. European Urology , 80 (2) pp. 263-265. 10.1016/j.eururo.2021.05.017. Green open access
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Schmidt, NM; Wing, PAC; Diniz, MO; Pallett, LJ; Swadling, L; Harris, JM; Burton, AR; ... Maini, MK; + view all (2021) Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint. Nature Communications , 12 , Article 2814. 10.1038/s41467-021-22967-7. Green open access
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Schöffski, P; Kubickova, M; Wozniak, A; Blay, JY; Strauss, SJ; Stacchiotti, S; Switaj, T; ... Kasper, B; + view all (2021) Long-term efficacy update of crizotinib in patients with advanced, inoperable inflammatory myofibroblastic tumour from EORTC trial 90101 CREATE. European Journal of Cancer , 156 pp. 12-23. 10.1016/j.ejca.2021.07.016. Green open access
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Sereno, M; He, Z; Smith, CR; Baena, J; Das, M; Hastings, RK; Rake, G; ... Le Quesne, J; + view all (2021) Inclusion of multiple high‐risk histopathological criteria improves the prediction of adjuvant chemotherapy efficacy in lung adenocarcinoma. Histopathology 10.1111/his.14301. (In press). Green open access
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Shamji, MH; Singh, I; Layhadi, JA; Ito, C; Karamani, A; Kouser, L; Sharif, H; ... Radin, AR; + view all (2021) Passive Prophylactic Administration with a Single Dose of Anti-Fel d 1 Monoclonal Antibodies REGN1908-1909 in Cat Allergen-Induced Allergic Rhinitis: A Randomized, Double-blind, Placebo Controlled Trial. American Journal of Respiratory and Critical Care Medicine , 204 (1) pp. 23-33. 10.1164/rccm.202011-4107OC. Green open access
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Shen, J; Zhuang, W; Xu, C; Jin, K; Chen, B; Tian, D; Hiley, C; ... Qiao, G; + view all (2021) Surgery or Non-surgical Treatment of <= 8 mm Non-small Cell Lung Cancer: A Population-Based Study. Frontiers in Surgery , 8 , Article ARTN 632. 10.3389/fsurg.2021.632561. Green open access
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Simpson, BS; Pye, H; Whitaker, HC; (2021) The oncological relevance of fragile sites in cancer. Communications Biology , 4 (1) , Article 567. 10.1038/s42003-021-02020-5. Green open access
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Soosaipillai, G; Wu, A; Dettorre, GM; Diamantis, N; Chester, J; Moss, C; Aguilar-Company, J; ... Izuzquiza, M; + view all (2021) Specialist palliative and end-of-life care for patients with cancer and SARS-CoV-2 infection: a European perspective. Therapeutic Advances in Medical Oncology , 13 pp. 1-17. 10.1177/17588359211042224. Green open access
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Stacchiotti, S; Miah, AB; Frezza, AM; Messiou, C; Morosi, C; Caraceni, A; Antonescu, CR; ... Gronchi, A; + view all (2021) Enithelioid hemangioendothelioma, an ultra-rare cancer: a consensus paper from the community of experts. ESMO OPEN , 6 (3) , Article 100170. 10.1016/j.esmoop.2021.100170. Green open access
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Strauss, SJ; Frezza, AM; Abecassis, N; Bajpai, J; Bauer, S; Biagini, R; Bielack, S; ... Stacchiotti, S; + view all (2021) Bone sarcomas: ESMO-EURACAN-GENTURIS-ERN PaedCan Clinical Practice Guideline for diagnosis, treatment and follow-up. Annals of Oncology , 32 (12) pp. 1520-1536. 10.1016/j.annonc.2021.08.1995. Green open access
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Sufi, J; Qin, X; Rodriguez, FC; Bu, YJ; Vlckova, P; Zapatero, MR; Nitz, M; (2021) Multiplexed single-cell analysis of organoid signaling networks. Nature Protocols , 16 pp. 4897-4918. 10.1038/s41596-021-00603-4. Green open access
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Sun, H; Cao, S; Mashl, RJ; Mo, C-K; Zaccaria, S; Wendl, MC; Davies, SR; ... Ding, L; + view all (2021) Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment. Nature Communications , 12 , Article 5086. 10.1038/s41467-021-25177-3. Green open access
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Szikriszt, B; Póti, Á; Németh, E; Kanu, N; Swanton, C; Szüts, D; (2021) A comparative analysis of the mutagenicity of platinum-containing chemotherapeutic agents reveals direct and indirect mutagenic mechanisms. Mutagenesis , 36 (1) pp. 75-86. 10.1093/mutage/geab005. Green open access
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Taavitsainen, S; Engedal, N; Cao, S; Handle, F; Erickson, A; Prekovic, S; Wetterskog, D; ... Urbanucci, A; + view all (2021) Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse. Nature Communications , 12 (1) , Article 5307. 10.1038/s41467-021-25624-1. Green open access
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Tabernero, J; Grothey, A; Van Cutsem, E; Yaeger, R; Wasan, H; Yoshino, T; Desai, J; ... Kopetz, S; + view all (2021) Encorafenib Plus Cetuximab as a New Standard of Care for Previously Treated BRAF V600E–Mutant Metastatic Colorectal Cancer: Updated Survival Results and Subgroup Analyses from the BEACON Study. Journal of Clinical Oncology , 39 (4) pp. 273-284. 10.1200/JCO.20.02088. Green open access
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Tabish, TA; Abbas, A; Narayan, RJ; (2021) Graphene nanocomposites for transdermal biosensing. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology , 13 (4) , Article e1699. 10.1002/wnan.1699. Green open access
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Terziev, R; Psimaras, D; Marie, Y; Feuvret, L; Berzero, G; Jacob, J; Dehais, C; ... Ricard, D; + view all (2021) Cumulative incidence and risk factors for radiation induced leukoencephalopathy in high grade glioma long term survivors. Scientific Reports , 11 (1) , Article 10176. 10.1038/s41598-021-89216-1. Green open access
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Thol, K; McGranahan, N; (2021) Potential Use of Shared Frameshift Mutations in 'Off-the-Shelf' Neoantigen Vaccines. Trends in Cancer , 7 (3) pp. 175-177. 10.1016/j.trecan.2021.01.002. Green open access
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van Maldegem, F; Valand, K; Cole, M; Patel, H; Angelova, M; Rana, S; Colliver, E; ... Downward, J; + view all (2021) Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry. Nature Communications , 12 (1) , Article 5906. 10.1038/s41467-021-26214-x. Green open access
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Vanhaesebroeck, B; Perry, MWD; Brown, JR; André, F; Okkenhaug, K; (2021) PI3K inhibitors are finally coming of age. Nature Reviews Drug Discovery , 20 pp. 741-769. 10.1038/s41573-021-00209-1. Green open access
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Vendramin, R; Litchfield, K; Swanton, C; (2021) Cancer evolution: Darwin and beyond. EMBO Journal , Article e108389. 10.15252/embj.2021108389. Green open access
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Venkatesan, S; Angelova, M; Bartkova, J; Bakhoum, SF; Bartek, J; Kanu, N; Swanton, C; (2021) APOBEC3 as a driver of genetic intratumor heterogeneity. Molecular and Cellular Oncology 10.1080/23723556.2021.2014734. (In press). Green open access
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Venkatesan, S; Angelova, M; Puttick, C; Zhai, H; Caswell, DR; Lu, W-T; Dietzen, M; ... Consortium, T; + view all (2021) Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution. Cancer Discovery , 11 (10) pp. 2456-2473. 10.1158/2159-8290.CD-20-0725. Green open access
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Volz, E; Mishra, S; Chand, M; Barrett, JC; Johnson, R; Geidelberg, L; Hinsley, WR; ... Ferguson, NM; + view all (2021) Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England. Nature , 593 (7858) pp. 266-269. 10.1038/s41586-021-03470-x. Green open access
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Vusirikala, A; Ensor, D; Asokan, AK; Lee, AJX; Ray, R; Tsekes, D; Edwin, J; (2021) Hello, can you hear me? Orthopaedic clinic telephone consultations in the COVID-19 era- a patient and clinician perspective. World Journal of Orthopedics , 12 (1) pp. 24-34. 10.5312/wjo.v12.i1.24. Green open access
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Wainberg, ZA; Fuchs, CS; Tabernero, J; Shitara, K; Muro, K; Van Cutsem, E; Bang, Y-J; ... Chao, J; + view all (2021) Efficacy of Pembrolizumab Monotherapy for Advanced Gastric/Gastroesophageal Junction Cancer with Programmed Death Ligand 1 Combined Positive Score ≥10. Clinical Cancer Research , 27 (7) pp. 1923-1931. 10.1158/1078-0432.CCR-20-2980. Green open access
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Wall, EC; Wu, M; Harvey, R; Kelly, G; Warchal, S; Sawyer, C; Daniels, R; ... Bauer, DL; + view all (2021) AZD1222-induced neutralising antibody activity against SARS-CoV-2 Delta VOC. The Lancet 10.1016/S0140-6736(21)01462-8. (In press). Green open access
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Wall, EC; Wu, M; Harvey, R; Kelly, G; Warchal, S; Sawyer, C; Daniels, R; ... Bauer, DLV; + view all (2021) Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination. The Lancet 10.1016/s0140-6736(21)01290-3. (In press). Green open access
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Wong, YNS; Sng, CCT; Ottaviani, D; Patel, G; Chowdhury, A; Earnshaw, I; Sinclair, A; ... Lee, AJX; + view all (2021) Systemic anti-cancer therapy and metastatic cancer are independent mortality risk factors during two uk waves of the covid-19 pandemic at university college london hospital. Cancers , 13 (23) , Article 6085. 10.3390/cancers13236085. Green open access
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Wu, Y; Biswas, D; Swanton, C; (2021) Impact of cancer evolution on immune surveillance and checkpoint inhibitor response. Seminars in Cancer Biology 10.1016/j.semcancer.2021.02.013. (In press). Green open access
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Zhang, M; Luo, J-L; Sun, Q; Harber, J; Dawson, AG; Nakas, A; Busacca, S; ... Fennell, DA; + view all (2021) Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment. Nature Communications , 12 (1) , Article 1751. 10.1038/s41467-021-21798-w. Green open access
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Zhao, Y; Fu, X; Lopez, JI; Rowan, A; Au, L; Fendler, A; Hazell, S; ... Litchfield, K; + view all (2021) Selection of metastasis competent subclones in the tumour interior. Nature Ecology & Evolution , 5 pp. 1033-1045. 10.1038/s41559-021-01456-6. Green open access
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Zhao, Y; Morka, N; Simpson, BSS; Freeman, A; Kirkham, A; Kelly, D; Whitaker, HC; ... Norris, JM; + view all (2021) Prostate-specific membrane antigen positron emission tomography compared to multiparametric MRI for prostate cancer diagnosis: a protocol for a systematic review and meta-analysis. BMJ Open , 11 (12) , Article e052277. 10.1136/bmjopen-2021-052277. Green open access
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Zoumpoulidou, G; Alvarez-Mendoza, C; Mancusi, C; Ahmed, R-M; Denman, M; Steele, CD; Tarabichi, M; ... Mittnacht, S; + view all (2021) Therapeutic vulnerability to PARP1,2 inhibition in RB1-mutant osteosarcoma. Nature Communications , 12 (1) , Article 7064. 10.1038/s41467-021-27291-8. Green open access
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Proceedings paper

Sashittal, P; Zaccaria, S; El-Kebir, M; (2021) Parsimonious clone tree reconciliation in cancer. In: 21st International Workshop on Algorithms in Bioinformatics (WABI 2021). (pp. 9:1-9:21). Schloss Dagstuhl -- Leibniz-Zentrum für Informatik: Dagstuhl, Germany. Green open access
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Zhang, Hanyun; Grunewald, Tami; Akarca, Ayse U; Ledermann, Jonathan A; Marafioti, Teresa; Yuan, Yinyin; (2021) Symmetric Dense Inception Network for Simultaneous Cell Detection and Classification in Multiplex Immunohistochemistry Images. In: Atzori, Manfredo and Burlutskiy, Nikolay and Ciompi, Francesco and Li, Zhang and Minhas, Fayyaz and Müller, Henning and Peng, Tingying and Rajpoot, Nasir and Torben­_Nielsen, Ben and van der Laak, Jeroen and Veta, Mitko and Yuan, Yinyin and Zlobec, Inti, (eds.) Proceedings of the MICCAI Workshop on Computational Pathology. (pp. pp. 246-257). PMLR Green open access
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Working / discussion paper

Fendler, Annika; Au, Lewis; Shepherd, Scott TC; Byrne, Fiona; Cerrone, Maddalena; Boos, Laura Amanda; Rzeniewicz, Karolina; ... Turajlic, Samra; + view all (2021) Functional antibody and T-cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study. Research Square: Durham, NC, USA. Green open access
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Thesis

Abbosh, Christopher; (2021) Cell-free DNA in early-stage non-small cell lung cancer. Doctoral thesis (Ph.D), UCL (University College London).

Jayaram, Anuradha Krishna; (2021) Leveraging circulating tumour DNA to dissect the evolutionary genomic dynamics of drug resistance in prostate cancer. Doctoral thesis (Ph.D), UCL (University College London).

Lau, Evelyn Keet Wai; (2021) Genomic and epigenomic impact of oncogenic mutation in the PIK3CA gene. Doctoral thesis (Ph.D), UCL (University College London).

Pearce, David; (2021) Investigation of fibulin-2 in pulmonary fibrosis. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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This list was generated on Mon Sep 16 02:32:02 2024 BST.