Thol, K;
McGranahan, N;
(2021)
Potential Use of Shared Frameshift Mutations in 'Off-the-Shelf' Neoantigen Vaccines.
Trends in Cancer
, 7
(3)
pp. 175-177.
10.1016/j.trecan.2021.01.002.
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Abstract
Neoantigens derived from frameshift mutations in microsatellite unstable tumours are more commonly shared between different patients' cancers compared with neoantigens arising from missense mutations. A recent study by Roudko et al. evaluates the immunogenicity of shared frameshift neoantigens, which could potentially be used in ‘off-the-shelf’ neoantigen vaccines.
| Type: | Article |
|---|---|
| Title: | Potential Use of Shared Frameshift Mutations in 'Off-the-Shelf' Neoantigen Vaccines |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.trecan.2021.01.002 |
| Publisher version: | https://doi.org/10.1016/j.trecan.2021.01.002 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Oncology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10130986 |
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