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Article

Abbott, TEF; Fowler, AJ; Pelosi, P; de Abreu, MG; Moller, AM; Canet, J; Creagh-Brown, B; ... StEP-COMPAC Group, .; + view all (2018) A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications. British Journal of Anaesthesia , 120 (5) pp. 1066-1079. 10.1016/j.bja.2018.02.007. Green open access
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Abdelrazeq, S; Ray, S; Rogers, L; Inwald, DP; Noren, DP; Peters, MJ; (2018) Age-associated blood pressure distributions in paediatric intensive care units differ from healthy children. [Letter]. Intensive Care Medicine , 44 (3) pp. 384-386. 10.1007/s00134-017-5017-4. Green open access
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Abdul-Razak, HH; Rocca, CJ; Howe, SJ; Alonso-Ferrero, ME; Wang, J; Gabriel, R; Bartholomae, CC; ... Yanez-Munoz, RJ; + view all (2018) Molecular Evidence of Genome Editing in a Mouse Model of Immunodeficiency. Scientific Reports , 8 , Article 8214. 10.1038/s41598-018-26439-9. Green open access
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Abola, RE; Bennett-Guerrero, E; Kent, ML; Feldman, LS; Fiore, JF; Shaw, AD; Thacker, JKM; ... Miller, TE; + view all (2018) American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Patient-Reported Outcomes in an Enhanced Recovery Pathway. [Review]. Anesthesia and Analgesia , 126 (6) pp. 1874-1882. 10.1213/ANE.0000000000002758. Green open access
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Almarza Novoa, E; Kasbekar, S; Thrasher, AJ; Kohn, DB; Sevilla, J; Nguyen, T; Schwartz, JD; (2018) Leukocyte adhesion deficiency-I: A comprehensive review of all published cases. Journal of Allergy and Clinical Immunology: In Practice , 6 (4) 1418-1420.e10. 10.1016/j.jaip.2017.12.008. Green open access
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Apps, JR; Carreno, G; Mario Gonzalez-Meljem, J; Haston, S; Guiho, R; Cooper, JE; Manshaei, S; ... Martinez-Barbera, JP; + view all (2018) Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target. Acta Neuropathologica , 135 (5) pp. 757-777. 10.1007/s00401-018-1830-2. Green open access
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Arthur, VL; Shuldiner, E; Remmers, EF; Hinks, A; Grom, AA; Foell, D; Martini, A; ... Ombrello, MJ; + view all (2018) IL1RN Variation Influences both Disease Susceptibility and Response to Human Recombinant IL-1RA Therapy in Systemic Juvenile Idiopathic Arthritis. Arthritis & Rheumatology , 70 (8) pp. 1319-1330. 10.1002/art.40498. Green open access
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Ashorn, P; Hallamaa, L; Allen, LH; Ashorn, U; Chandrasiri, U; Deitchler, M; Doyle, R; ... Dewey, KG; + view all (2018) Co-causation of reduced newborn size by maternal undernutrition, infections, and inflammation. Maternal and Child Nutrition 10.1111/mcn.12585. Green open access
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Balloch, A; Roalfe, L; Ekstrom, N; Nguyen, CD; Spry, L; Marimla, RA; Licciardi, PV; ... Mulholland, EK; + view all (2018) Interlaboratory Comparison of the Pneumococcal Multiplex Opsonophagocytic Assays and Their Level of Agreement for Determination of Antibody Function in Pediatric Sera. mSphere , 3 (2) , Article e00070-18. 10.1128/mSphere.00070-18. Green open access
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Bamford, A; Turkova, A; Lyall, H; Foster, C; Klein, N; Bastiaans, D; Burger, D; ... Welch, S; + view all (2018) Paediatric European Network for Treatment of AIDS (PENTA) guidelines for treatment of paediatric HIV-1 infection 2015: Optimizing health in preparation for adult life. HIV Medicine , 19 (1) e1-e42. 10.1111/hiv.12217. Green open access
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Banerjee, KK; Saxena, M; Kumar, N; Chen, L; Cavazza, A; Toke, NH; O'Neill, NK; ... Shivdasani, RA; + view all (2018) Enhancer, transcriptional, and cell fate plasticity precedes intestinal determination during endoderm development. Genes and Development , 32 (21-22) pp. 1430-1442. 10.1101/gad.318832.118. Green open access
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Barker, CIS; Standing, JF; Kelly, LE; Hanly Faught, L; Needham, AC; Rieder, MJ; de Wildt, SN; (2018) Pharmacokinetic studies in children: recommendations for practice and research. Archives of Disease in Childhood 10.1136/archdischild-2017-314506. Green open access
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Barzaghi, F; Hernandez, LCA; Neven, B; Ricci, S; Kucuk, ZY; Bleesing, JJ; Nademi, Z; ... Bacchetta, R; + view all (2018) Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study. Journal of Allergy and Clinical Immunology , 141 (3) 1036-1049.e5. 10.1016/j.jaci.2017.10.041. Green open access
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Beilin, C; Choudhuri, K; Bouma, G; Malinova, D; Llodra, J; Stokes, D; Shimaoka, M; ... Burns, S; + view all (2018) Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse [version 1]. Wellcome Open Research 10.12688/wellcomeopenres.14493.1. Green open access
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Beilin, C; Choudhuri, K; Bouma, G; Malinova, D; Llodra, J; Stokes, DL; Shimaoka, M; ... Burns, SO; + view all (2018) Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse [version 2; referees: 2 approved]. Wellcome Open Research , 3 , Article 84. 10.12688/wellcomeopenres.14493.2. Green open access
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Bending, D; Martín, PP; Paduraru, A; Ducker, C; Marzaganov, E; Laviron, M; Kitano, S; ... Ono, M; + view all (2018) A timer for analyzing temporally dynamic changes in transcription during differentiation in vivo. Journal of Cell Biology , 217 (8) pp. 2931-2950. 10.1083/jcb.201711048. Green open access
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Bending, D; Paduraru, A; Ducker, CB; Martin, PP; Crompton, T; Ono, M; (2018) A temporally dynamic Foxp3 autoregulatory transcriptional circuit controls the effector Treg programme. The EMBO Journal , 37 (16) , Article e99013. 10.15252/embj.201899013. Green open access
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Best, S; Shoemark, A; Rubbo, B; Patel, MP; Fassad, MR; Dixon, M; Rogers, AV; ... Hogg, C; + view all (2018) Risk factors for situs defects and congenital heart disease in primary ciliary dyskinesia. Thorax , 74 (2) 10.1136/thoraxjnl-2018-212104. Green open access
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Biswas, A; Shouval, DS; Griffith, A; Goettel, JA; Field, M; Kang, YH; Konnikova, L; ... Snapper, SB; + view all (2018) WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis. Nature Communications , 9 , Article 1779. 10.1038/s41467-018-03670-6. Green open access
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Blackwood, DH; Vindrola-Padros, C; Mythen, MG; Walker, D; (2018) Advance-care-planning and end-of-life discussions in the perioperative period: a review of healthcare professionals' knowledge, attitudes, and training. British Journal of Anaesthesia 10.1016/j.bja.2018.05.075. (In press). Green open access
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Booth, CAG; Barkas, N; Neo, WH; Boukarabila, H; Soilleux, EJ; Giotopoulos, G; Farnoud, N; ... Mead, AJ; + view all (2018) Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors. Cancer Cell , 33 (2) 274-291.e8. 10.1016/j.ccell.2018.01.006. Green open access
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Bouwes Bavinck, JN; Feltkamp, MCW; Green, AC; Fiocco, M; Euvrard, S; Harwood, CA; Proby, CM; ... EPI-HPV-UV-CA group, .; + view all (2018) Human papillomavirus and post-transplant cutaneous squamous-cell carcinoma: a multicenter, prospective cohort study. American Journal of Transplantation , 18 (5) pp. 1220-1230. 10.1111/ajt.14537. Green open access
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Brendel, C; Rothe, M; Santilli, G; Charrier, S; Stein, S; Kunkel, H; Abriss, D; ... Grez, M; + view all (2018) Non-Clinical Efficacy and Safety Studies on G1XCGD, a Lentiviral Vector for Ex Vivo Gene Therapy of X-Linked Chronic Granulomatous Disease. Human Gene Therapy Clinical Development , 29 (2) pp. 69-79. 10.1089/humc.2017.245. Green open access
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Brenner, N; Mentzer, AJ; Butt, J; Michel, A; Prager, K; Brozy, J; Weissbrich, B; ... Waterboer, T; + view all (2018) Validation of Multiplex Serology detecting human herpesviruses 1-5. PLoS One , 13 (12) , Article e0209379. 10.1371/journal.pone.0209379. Green open access
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Breuer, J; (2018) Molecular Genetic Insights Into Varicella Zoster Virus (VZV), the vOka Vaccine Strain, and the Pathogenesis of Latency and Reactivation. The Journal of Infectious Diseases , 218 (suppl_2) S75-S80. 10.1093/infdis/jiy279. Green open access
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Brogan, P; Eleftheriou, D; (2018) Vasculitis update: pathogenesis and biomarkers. Pediatric Nephrology , 33 (2) pp. 187-198. 10.1007/s00467-017-3597-4. Green open access
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Brown, JR; Bharucha, T; Breuer, J; (2018) Encephalitis diagnosis using metagenomics: application of next generation sequencing for undiagnosed cases. Journal of Infection , 76 (3) pp. 225-240. 10.1016/j.jinf.2017.12.014. Green open access
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Brunner, K; John, CM; Phillips, NJ; Alber, DG; Gemmell, MR; Hansen, R; Nielsen, HL; ... Jarvis, GA; + view all (2018) Novel Campylobacter concisus Lipooligosaccharide is a Determinant of Inflammatory Potential and Virulence. Journal of Lipid Research , 59 (10) pp. 18931-1905. 10.1194/jlr.M085860. Green open access
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Bryant, D; Liu, Y; Datta, S; Hariri, H; Seda, M; Anderson, G; Peskett, E; ... Stanier, PM; + view all (2018) SNX14 mutations affect endoplasmic reticulum-associated neutral lipid metabolism in autosomal recessive spinocerebellar ataxia 20. Human Molecular Genetics , 27 (11) pp. 1927-1940. 10.1093/hmg/ddy101. Green open access
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Brynildsrud, OB; Pepperell, CS; Suffys, P; Grandjean, L; Monteserin, J; Debech, N; Bohlin, J; ... Eldholm, V; + view all (2018) Global Expansion of Mycobacterium Tuberculosis Lineage 4 Shaped by Colonial Migration and Local Adaptation. Science Advances , 4 (10) , Article eaat5869. 10.1126/sciadv.aat5869. Green open access
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Bucciol, G; Moens, L; Payne, K; Wollants, E; Mekahli, D; Levtchenko, E; Vermeulen, F; ... Meyts, I; + view all (2018) Chronic Aichi Virus Infection in a Patient with X-Linked Agammaglobulinemia. Journal of Clinical Immunology , 38 (7) pp. 748-752. 10.1007/s10875-018-0558-z. Green open access
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Calvo-Vecino, JM; Ripollés-Melchor, J; Mythen, MG; Casans-Francés, R; Balik, A; Artacho, JP; Martínez-Hurtado, E; ... FEDORA Trial Investigators Group; + view all (2018) Effect of goal-directed haemodynamic therapy on postoperative complications in low-moderate risk surgical patients: a multicentre randomised controlled trial (FEDORA trial). British Journal of Anaesthesia , 120 (4) pp. 734-744. 10.1016/j.bja.2017.12.018. Green open access
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Chan, W-Y; Entwisle, C; Ercoli, G; Ramos-Sevillano, E; McIlgorm, A; Cecchini, P; Bailey, C; ... Brown, JS; + view all (2018) A novel, multiple-antigen pneumococcal vaccine protects against lethal Streptococcus pneumoniae challenge. Infection and Immunity 10.1128/IAI.00846-18. (In press). Green open access
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Chapman, S; Wray, J; Oulton, K; Peters, M; (2018) ‘Death is not the answer’: the challenge of measuring the impact of early warning systems. [Editorial comment]. Archives of Disease in Childhood , 104 (3) pp. 210-211. 10.1136/archdischild-2018-315392. Green open access
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Chellen, Shavindra; Whittaker, Elizabeth; Eisenhut, Michael; Grandjean, Louis; (2018) Cerebral tuberculomas in a 6-year-old girl causing central diabetes insipidus. BMJ Case Reports , 2018 10.1136/bcr-2018-226590. Green open access
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Clark, SA; Doyle, R; Lucidarme, J; Borrow, R; Breuer, J; (2018) Targeted DNA enrichment and whole genome sequencing of Neisseria meningitidis directly from clinical specimens. International Journal of Medical Microbiology , 308 (2) pp. 256-262. 10.1016/j.ijmm.2017.11.004. Green open access
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Coll, F; Phelan, J; Hill-Cawthorne, GA; Nair, MB; Mallard, K; Ali, S; Abdallah, AM; ... Clark, TG; + view all (2018) Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis. Nature Genetics , 50 (2) pp. 307-316. 10.1038/s41588-017-0029-0. Green open access
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Collins, J; (2018) Time to switch to second-line antiretroviral therapy in children with HIV in Europe and Thailand. Clinical Infectious Diseases , 66 (4) pp. 594-603. 10.1093/cid/cix854. Green open access
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Comitato, A; Subramanian, P; Turchiano, G; Montanari, M; Becerra, SP; Marigo, V; (2018) Pigment epithelium-derived factor hinders photoreceptor cell death by reducing intracellular calcium in the degenerating retina. Cell Death & Disease , 9 , Article 560. 10.1038/s41419-018-0613-y. Green open access
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Correia, S; Bridges, R; Wegner, F; Venturini, C; Palser, A; Middeldorp, JM; Cohen, JI; ... Farrell, PJ; + view all (2018) Sequence Variation of Epstein-Barr Virus: Viral Types, Geography, Codon Usage, and Diseases. Journal of Virology , 92 (22) , Article e01132-18. 10.1128/JVI.01132-18. Green open access
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Cossu, G; Birchall, M; Brown, T; De Coppi, P; Culme-Seymour, E; Gibbon, S; Hitchcock, J; ... Wilson, JGS; + view all (2018) Lancet Commission: Stem Cells and Regenerative Medicine. The Lancet , 391 (10123) pp. 883-910. 10.1016/S0140-6736(17)31366-1. Green open access
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CRyPTIC consortium and on behalf of the 100,000 Genomes Project, .; (2018) Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing. New England Journal of Medicine , 379 (15) 10.1056/NEJMoa1800474. Green open access
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da Cruz, L; Fynes, K; Georgiadis, O; Kerby, J; Luo, YH; Ahmado, A; Vernon, A; ... Coffey, PJ; + view all (2018) Phase 1 clinical study of an embryonic stem cell-derived retinal pigment epithelium patch in age-related macular degeneration. Nature Biotechnology , 36 (4) pp. 328-337. 10.1038/nbt.4114. Green open access
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Danquah, CA; Kakagianni, E; Khondkar, P; Maitra, A; Rahman, M; Evangelopoulos, D; McHugh, TD; ... Gibbons, S; + view all (2018) Analogues of Disulfides from Allium stipitatum Demonstrate Potent Anti-tubercular Activities through Drug Efflux Pump and Biofilm Inhibition. Scientific Reports , 8 , Article 1150. 10.1038/s41598-017-18948-w. Green open access
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Davies, T; Gilbert-Kawai, E; Wythe, S; Meale, P; Mythen, M; Levett, D; Mitchell, K; ... Xtreme Everest 2 Research Group; + view all (2018) Sustained vasomotor control of skin microcirculation in Sherpas versus altitude-naive lowlanders: Experimental evidence from Xtreme Everest 2. Experimental Physiology , 103 (11) pp. 1494-1504. 10.1113/EP087236. Green open access
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De Benedetti, F; Gattorno, M; Anton, J; Ben-Chetrit, E; Frenkel, J; Hoffman, HM; Koné-Paut, I; ... Junge, G; + view all (2018) Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes. The New England Journal of Medicine , 378 (20) pp. 1908-1919. 10.1056/NEJMoa1706314. Green open access
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De Iorio, M; Gallot, N; Valcarcel, B; Wedderburn, L; (2018) A Bayesian semiparametric Markov regression model for juvenile dermatomyositis. Statistics in Medicine , 37 (10) pp. 1711-1731. 10.1002/sim.7613. Green open access
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De Luca, D; Harrison, DA; Peters, MJ; (2018) ‘Lumping or splitting’ in paediatric acute respiratory distress syndrome (PARDS). [Editorial comment]. Intensive Care Medicine , 44 (9) pp. 1548-1550. 10.1007/s00134-018-5323-5. Green open access
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de Majo, M; Topp, SD; Smith, BN; Nishimura, AL; Chen, H-J; Gkazi, AS; Miller, J; ... Shaw, CE; + view all (2018) ALS-associated missense and nonsense TBK1 mutations can both cause loss of kinase function. Neurobiology of Aging , 71 266.e1-266.e10. 10.1016/j.neurobiolaging.2018.06.015. Green open access
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Deakin, CT; Campanilho-Marques, R; Simou, S; Moraitis, E; Wedderburn, LR; Pullenayegum, E; Pilkington, CA; (2018) Efficacy and Safety of Cyclophosphamide Treatment in Severe Juvenile Dermatomyositis Shown by Marginal Structural Modeling. Arthritis & Rheumatology , 70 (5) pp. 785-793. 10.1002/art.40418. Green open access
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Deng, Y; Herbert, J; Smith, CM; Smyth, R; (2018) An in vitro transepithelial migration assay to evaluate the role of neutrophils in Respiratory Syncytial Virus (RSV) induced epithelial damage. Scientific Reports , 8 , Article 6777. 10.1038/s41598-018-25167-4. Green open access
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Deola, S; Guerrouahen, BS; Sidahmed, H; Al-Mohannadi, A; Elnaggar, M; Elsadig, R; Abdelalim, EM; ... Cugno, C; + view all (2018) Tailoring cells for clinical needs: Meeting report from the Advanced Therapy in Healthcare symposium (October 28–29 2017, Doha, Qatar). Journal of Translational Medicine , 16 p. 276. 10.1186/s12967-018-1652-y. Green open access
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Depledge, DP; Cudini, J; Kundu, S; Atkinson, C; Brown, JR; Haque, T; Houldcroft, CJ; ... Breuer, J; + view all (2018) High Viral Diversity and Mixed Infections in Cerebral Spinal Fluid From Cases of Varicella Zoster Virus Encephalitis. The Journal of Infectious Diseases 10.1093/infdis/jiy358. Green open access
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Depledge, DP; Ouwendijk, WJD; Sadaoka, T; Braspenning, SE; Mori, Y; Cohrs, RJ; Verjans, GMGM; (2018) A spliced latency-associated VZV transcript maps antisense to the viral transactivator gene 61. Nature Communications , 9 (1) , Article 1167. 10.1038/s41467-018-03569-2. Green open access
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Devakumar, D; Bamford, A; Ferreira, MU; Broad, J; Rosch, RE; Groce, N; Breuer, J; ... Abubakar, I; + view all (2018) Infectious causes of microcephaly: epidemiology, pathogenesis, diagnosis, and management. The Lancet Infectious Diseases , 18 (1) e13-e13. 10.1016/S1473-3099(17)30398-5. Green open access
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Domislic, B; Harvey, A; Shannon, H; (2018) Developmental outcome measures in neonatal physiotherapy services of the United Kingdom: a survey of current use, and facilitators and barriers to their implementation. Journal of the Association for Chartered Physiotherapists in Paediatrics , 9 (1) pp. 13-28. Green open access
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Dotres Martinez, CP; Linares-Perez, N; Toledo-Romani, ME; Ricardo Delgado, Y; Puga Gomez, R; Paredes Moreno, B; Rodriguez-Noda, LM; ... Alvarez, A; + view all (2018) Safety and immunogenicity of the Cuban heptavalent pneumococcal conjugate vaccine in healthy infants. Results from a double-blind randomized control trial Phase I. Vaccine , 36 (32 Pt B) pp. 4944-4951. 10.1016/j.vaccine.2018.05.027. Green open access
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Doyle, R; Gondwe, A; Fan, Y-M; Maleta, K; Ashorn, P; Klein, N; Harris, K; (2018) Lactobacillus-deficient vaginal microbiota dominate post-partum women in rural Malawi. Applied and Environmental Microbiology , 84 (6) , Article e02150-17. 10.1128/AEM.02150-17. Green open access
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Doyle, RM; Burgess, C; Williams, R; Gorton, R; Booth, H; Brown, J; Bryant, JM; ... Breuer, J; + view all (2018) Direct whole genome sequencing of sputum accurately identifies drug resistant Mycobacterium tuberculosis faster than MGIT culture sequencing. Journal of Clinical Microbiology 10.1128/JCM.00666-18. (In press). Green open access
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Dunning, J; Blankley, S; Hoang, LT; Cox, M; Graham, CM; James, PL; Bloom, CI; ... Openshaw, PJM; + view all (2018) Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza. Nature Immunology , 19 pp. 625-635. 10.1038/s41590-018-0111-5. Green open access
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Ekbal, NJ; Hennis, P; Dyson, A; Mythen, M; James, MFM; Singer, M; (2018) The anion study: effect of different crystalloid solutions on acid base balance, physiology, and survival in a rodent model of acute isovolaemic haemodilution. Br J Anaesth , 120 (6) pp. 1412-1419. 10.1016/j.bja.2018.01.026. Green open access
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Eleftheriou, D; Brogan, PA; (2018) Vasculitis in children. Paediatrics and Child Health , 28 (2) pp. 57-63. 10.1016/j.paed.2017.10.009. Green open access
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Elfeky, RA; Furtado-Silva, JM; Chiesa, R; Rao, K; Amrolia, P; Lucchini, G; Gilmour, K; ... Veys, P; + view all (2018) One hundred percent survival after transplantation of 34 patients with Wiskott-Aldrich syndrome over 20 years. [Letter]. Journal of Allergy and Clinical Immunology , 142 (5) 1654-1656.e7. 10.1016/j.jaci.2018.06.042. Green open access
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Elfeky, RA; Furtado-Silva, JM; Chiesa, R; Rao, K; Lucchini, G; Amrolia, P; Worth, A; ... Veys, P; + view all (2018) Umbilical cord blood transplantation without in vivo T-cell depletion for children with MHC class II deficiency. Journal of Allergy and Clinical Immunology , 141 (6) 2279-2282.e2. 10.1016/j.jaci.2017.10.051. Green open access
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Elmi, A; Dorey, A; Watson, E; Jagatia, H; Inglis, NF; Gundogdu, O; Bajaj-Elliott, M; ... Dorrell, N; + view all (2018) The bile salt sodium taurocholate induces Campylobacter jejuni outer membrane vesicle production and increases OMV-associated proteolytic activity. Cellular Microbiology , 20 (3) , Article e12814. 10.1111/cmi.12814. Green open access
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Esona, MD; Roy, S; Rungsrisuriyachai, K; Gautam, R; Hermelijn, S; Rey-Benito, G; Bowen, MD; (2018) Molecular characterization of a human G20P[28] rotavirus a strain with multiple genes related to bat rotaviruses. Infection, Genetics and Evolution , 57 pp. 166-170. 10.1016/j.meegid.2017.11.025. Green open access
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Evans, C; Fitzgerald, F; Cunnington, A; (2018) Review of UK malaria treatment guidelines 2016 (Public Health England Advisory Committee on Malaria Prevention). Archives of Disease in Childhood: Education and Practice Edition 10.1136/archdischild-2017-314343. (In press). Green open access
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Farmery, JHR; Smith, ML; Lynch, AG; Huissoon, A; Furnell, A; Mead, A; Levine, AP; ... Tan, Y; + view all (2018) Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data (vol 8, 1300, 2018). Scientific Reports , 8 , Article 13376. 10.1038/s41598-018-31524-0. Green open access
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Farmery, JHR; Smith, ML; NIHR BioResource - Rare Diseases, .; Lynch, AG; Mead, A; Levine, AP; Manzur, A; ... Huissoon, A; + view all (2018) Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data. Scientific Reports , 8 , Article 1300. 10.1038/s41598-017-14403-y. Green open access
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Farzan, N; Vijverberg, SJ; Hernandez-Pacheco, N; Bel, EHD; Berce, V; Bønnelykke, K; Bisgaard, H; ... Maitland-van der Zee, A-H; + view all (2018) 17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use. [Letter]. Allergy , 73 (10) pp. 2083-2088. 10.1111/all.13499. Green open access
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Fassad, MR; Shoemark, A; Legendre, M; Hirst, RA; Koll, F; le Borgne, P; Louis, B; ... Mitchison, HM; + view all (2018) Mutations in Outer Dynein Arm Heavy Chain DNAH9 Cause Motile Cilia Defects and Situs Inversus. The American Journal of Human Genetics 10.1016/j.ajhg.2018.10.016. (In press). Green open access
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Feinstein, Y; Walker, JC; Peters, MJ; Nadel, S; Pathan, N; Edmonds, N; Herberg, J; ... Ramnarayan, P; + view all (2018) Cohort profile of the Biomarkers of Acute Serious Illness in Children (BASIC) study: a prospective multicentre cohort study in critically ill children. BMJ Open , 8 (11) , Article e024729. 10.1136/bmjopen-2018-024729. Green open access
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Fernando, O; Tagalakis, AD; Shiekh Hassan Awwad, S; Brocchini, S; Khaw, PT; Hart, S; Yu-Wai-Man, C; (2018) Development of targeted siRNA nanocomplexes to prevent fibrosis in experimental glaucoma filtration surgery. Molecular Therapy , 26 (12) pp. 2812-2822. 10.1016/j.ymthe.2018.09.004. Green open access
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Fertleman, C; Aubugeau-Williams, P; Sher, C; Lim, A-N; Lumley, S; Delacroix, S; Pan, X; (2018) A Discussion of Virtual Reality As a New Tool for Training Healthcare Professionals. Frontiers in Public Health , 6 , Article 44. 10.3389/fpubh.2018.00044. Green open access
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Fitzgerald, F; Wing, K; Naveed, A; Gbessay, M; Ross, JCG; Checchi, F; Youkee, D; ... Yeung, S; + view all (2018) Development of a pediatric ebola predictive score, Sierra Leone. Emerging Infectious Diseases , 24 (2) pp. 311-319. 10.3201/eid2402.171018. Green open access
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Forbes, HJ; Williamson, E; Benjamin, L; Breuer, J; Brown, MM; Langan, SM; Minassian, C; ... Warren-Gash, C; + view all (2018) Association of herpesviruses and stroke: Systematic review and meta-analysis. PLoS One , 13 (11) , Article e0206163. 10.1371/journal.pone.0206163. Green open access
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Fox, T; Chakraverty, R; Burns, S; Carpenter, B; Thomson, K; Lowe, D; Fielding, A; ... Morris, EC; + view all (2018) Successful outcome following allogeneic hematopoietic stem cell transplantation in adults with primary immunodeficiency. Blood , 131 (8) pp. 917-931. 10.1182/blood-2017-09-807487. Green open access
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Frampton, D; Schwenzer, H; Marino, G; Butcher, LM; Pollara, G; Kriston-Vizi, J; Venturini, C; ... Fassati, A; + view all (2018) Molecular Signatures of Regression of the Canine Transmissible Venereal Tumor. Cancer Cell , 33 (4) 620-633.e6. 10.1016/j.ccell.2018.03.003. Green open access
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Fuller, DQ; Murphy, C; (2018) The origins and early dispersal of horsegram (Macrotyloma uniflorum), a major crop of ancient India. Genetic Resources and Crop Evolution , 65 (1) pp. 285-305. 10.1007/s10722-017-0532-2. Green open access
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Gassas, A; Sivaprakasam, P; Cummins, M; Breslin, P; Patrick, K; Slatter, M; Skinner, R; ... Amrolia, P; + view all (2018) High transplant-related mortality associated with haematopoietic stem cell transplantation for paediatric therapy-related acute myeloid leukaemia (t-AML). A study on behalf of the United Kingdom Paediatric Blood and Bone Marrow Transplant Group. Bone Marrow Transplantation , 53 (9) pp. 1165-1169. 10.1038/s41409-018-0157-x. Green open access
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Ge, Shufan; Beechinor, Ryan J; Hornik, Christoph P; Standing, Joseph F; Zimmerman, Kanecia; Cohen-Wolkowiez, Michael; Laughon, Matthew M; ... Gonzalez, Daniel; + view all (2018) External Evaluation of a Gentamicin Infant Population Pharmacokinetic Model Using Data from a National Electronic Health Record Database. Antimicrobial Agents and Chemotherapy , 62 (9) , Article e00669-18. 10.1128/AAC.00669-18. Green open access
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Gemmell, MR; Berry, S; Mukhopadhya, I; Hansen, R; Nielsen, HL; Bajaj-Elliott, M; Nielsen, H; (2018) Comparative genomics of Campylobacter concisus: Analysis of clinical strains reveals genome diversity and pathogenic potential. Emerging Microbes & Infections , 7 , Article 116. 10.1038/s41426-018-0118-x. Green open access
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Georgiadis, C; Preece, R; Nickolay, L; Etuk, A; Petrova, A; Ladon, D; Danyi, A; ... Qasim, W; + view all (2018) Long Terminal Repeat CRISPR-CAR-Coupled "Universal" T Cells Mediate Potent Anti-leukemic Effects. Molecular Therapy , 26 (5) pp. 1215-1227. 10.1016/j.ymthe.2018.02.025. Green open access
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Germovsek, E; Lutsar, I; Kipper, K; Karlsson, MO; Planche, T; Chazallon, C; Meyer, L; ... NeoMero Consortium; + view all (2018) Plasma and CSF pharmacokinetics of meropenem in neonates and young infants: results from the NeoMero studies. Journal of Antimicrobial Chemotherapy , Article dky128. 10.1093/jac/dky128. Green open access
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Ghorashian, S; Amrolia, P; Veys, P; (2018) Open access? Widening access to chimeric antigen receptor (CAR) therapy for ALL. Experimental Hematology , 66 pp. 5-16. 10.1016/j.exphem.2018.07.002. Green open access
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Ghosh, S; Carmo, M; Calero-Garcia, M; Ricciardelli, I; Bustamante Ogando, JC; Blundell, MP; Schambach, A; ... Gaspar, HB; + view all (2018) T cell gene therapy for perforin deficiency corrects cytotoxicity defects and prevents Haemophagocytic Lymphohistiocytosis manifestations. Journal of Allergy and Clinical Immunology , 142 (3) 904-913.e3. 10.1016/j.jaci.2017.11.050. Green open access
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Gkazi, AS; Margetts, BK; Attenborough, T; Mhaldien, L; Standing, JF; Oakes, T; Heather, JM; ... Adams, SP; + view all (2018) Clinical T Cell Receptor Repertoire Deep Sequencing and Analysis: An Application to Monitor Immune Reconstitution Following Cord Blood Transplantation. Frontiers in Immunology , 9 , Article 2547. 10.3389/fimmu.2018.02547. Green open access
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Gohar, F; Anink, J; Moncrieffe, H; Van Suijlekom-Smit, LWA; Prince, FHM; van Rossum, MAJ; Dolman, KM; ... Holzinger, D; + view all (2018) S100A12 Is Associated with Response to Therapy in Juvenile Idiopathic Arthritis. The Journal of Rheumatology , 45 (4) pp. 547-554. 10.3899/jrheum.170438. Green open access
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Gray, ER; Turbé, V; Lawson, VE; Page, RH; Cook, ZC; Ferns, RB; Nastouli, E; ... McKendry, RA; + view all (2018) Ultra-rapid, sensitive and specific digital diagnosis of HIV with a dual-channel SAW biosensor in a pilot clinical study. npj Digital Medicine , 1 , Article 35. 10.1038/s41746-018-0041-5. Green open access
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Gregson, RK; Skellett, S; Ray, S; Peters, MJ; (2018) Hard and fast, but within limits: is there a trade-off of stroke volume index and diastolic pressure in paediatric resuscitation? [Letter]. Intensive Care Medicine , 44 (2) pp. 254-256. 10.1007/s00134-017-4949-z. Green open access
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Hanns, L; Cordingley, L; Galloway, J; Norton, S; Carvalho, LA; Christie, D; Sen, D; ... Ioannou, Y; + view all (2018) Depressive symptoms, pain and disability for adolescent patients with JIA. Results from the Childhood Arthritis Prospective Study. Rheumatology , 57 (8) pp. 1381-1389. 10.1093/rheumatology/key088. Green open access
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Harjunmaa, U; Doyle, R; Järnstedt, J; Kamiza, S; Jorgensen, JM; Stewart, CP; Shaw, L; ... Ashorn, P; + view all (2018) Periapical infection may affect birth outcomes via systemic inflammation. Oral Diseases , 24 (5) pp. 847-855. 10.1111/odi.12817. Green open access
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Harris, S; Braggins, H; van Leeuwen, K; Gilmour, K; Buckland, MS; Roos, D; Lowe, DM; (2018) Male X-chromosome mosaicism leading to carrier phenotype and inheritance of chronic granulomatous disease. The Journal of Allergy and Clinical Immunology: In Practice , 6 (5) 1775-1777.e1. 10.1016/j.jaip.2018.01.017. Green open access
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Hawcutt, DB; Francis, B; Carr, DF; Jorgensen, AL; Yin, P; Wallin, N; O'Hara, N; ... Pirmohamed, M; + view all (2018) Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study. The Lancet Respiratory Medicine , 6 (6) pp. 442-450. 10.1016/S2213-2600(18)30058-4. Green open access
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Hecht, M; Veigure, R; Couchman, L; Barker, SCI; Standing, JF; Takkis, K; Evard, H; ... Kipper, K; + view all (2018) Utilization of data below the analytical limit of quantitation in pharmacokinetic analysis and modeling: promoting interdisciplinary debate. Bioanalysis , 10 (15) pp. 1229-1248. 10.4155/bio-2018-0078. Green open access
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Hedrick, TL; McEvoy, MD; Mythen, MMG; Bergamaschi, R; Gupta, R; Holubar, SD; Senagore, AJ; ... Miller, TE; + view all (2018) American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Gastrointestinal Dysfunction Within an Enhanced Recovery Pathway for Elective Colorectal Surgery. [Review]. Anesthesia and Analgesia , 126 (6) pp. 1896-1907. 10.1213/ANE.0000000000002742. Green open access
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Hendry, GJ; Shoop-Worrall, SJ; Riskowski, JL; Andrews, P; Baildam, E; Chieng, A; Davidson, J; ... Steultjens, M; + view all (2018) Prevalence and course of lower limb disease activity and walking disability over the first 5 years of juvenile idiopathic arthritis: results from the childhood arthritis prospective study. Rheumatology Advances in Practice , 2 (2) 10.1093/rap/rky039. Green open access
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Hill, S; Entwisle, C; Pang, Y; Joachim, M; McIlgorm, A; Dalton, K; Burbidge, P; ... Bailey, C; + view all (2018) Immunogenicity and mechanisms of action of PnuBioVax, a multi-antigen serotype-independent prophylactic vaccine against infection with Streptococcus pneumoniae. Vaccine , 36 (29) pp. 4255-4264. 10.1016/j.vaccine.2018.05.122. Green open access
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Hinks, A; Marion, MC; Cobb, J; Comeau, ME; Sudman, M; Ainsworth, HC; Bowes, J; ... Prahalad, S; + view all (2018) The genetic profile of RF-positive polyarticular juvenile idiopathic arthritis (JIA) resembles adult rheumatoid arthritis (RA). Arthritis & Rheumatology , 70 (6) pp. 957-962. 10.1002/art.40443. Gold open access
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Hong, Y; Standing, ASI; Nanthapisal, S; Sebire, N; Jolles, S; Omoyinmi, E; Verstegen, RH; ... Eleftheriou, D; + view all (2018) Autoinflammation due to homozygous S208 MEFV mutation. Annals of the Rheumatic Diseases , 78 (4) pp. 571-573. 10.1136/annrheumdis-2018-214102. Green open access
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Houldcroft, CJ; Roy, S; Morfopoulou, S; Margetts, BK; Depledge, DP; Cudini, J; Shah, D; ... Breuer, J; + view all (2018) Use of Whole-genome Sequencing of Adenovirus in Immunocompromised Paediatric Patients to Identify Nosocomial Transmission and Mixed-genotype Infection. The Journal of Infectious Diseases , 218 (8) pp. 1261-1271. 10.1093/infdis/jiy323. Green open access
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Houlihan, C; Frampton, D; Ferns, RB; Raffle, J; Grant, P; Reidy, M; Hail, L; ... Nastouli, E; + view all (2018) The use of whole genome sequencing in the investigation of a nosocomial influenza virus outbreak. The Journal of Infectious Diseases , 218 (9) pp. 1485-1489. 10.1093/infdis/jiy335. Green open access
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Howlett, PJ; Walder, AR; Lisk, DR; Fitzgerald, F; Sevalie, S; Lado, M; N Jai, A; ... Scott, JT; + view all (2018) Case series of severe neurologic sequelae of ebola virus disease during epidemic, Sierra Leone. Emerging Infectious Diseases , 24 (8) pp. 1412-1421. 10.3201/eid2408.171367. Green open access
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Hughes, F; Mythen, M; Montgomery, H; (2018) The sensitivity of the human thirst response to changes in plasma osmolality: a systematic review. [Review]. Perioperative Medicine , 7 , Article 1. 10.1186/s13741-017-0081-4. Green open access
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Inwald, D; Canter, RR; Woolfall, K; O'Hara, CB; Mouncey, PR; Zenasni, Z; Hudson, N; ... Rowan, KM; + view all (2018) Restricted fluid bolus versus current practice in children with septic shock: the FiSh feasibility study and pilot RCT. Health Technology Assessment , 22 (51) pp. 1-106. 10.3310/hta22510. Green open access
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Inwald, DP; Canter, R; Woolfall, K; Mouncey, P; Zenasni, Z; O'Hara, C; Carter, A; ... PERUKI (Paediatric Emergency Research in the UK and Ireland) and; + view all (2018) Restricted fluid bolus volume in early septic shock: results of the Fluids in Shock pilot trial. Archives of Disease in Childhood , 104 pp. 426-431. 10.1136/archdischild-2018-314924. Green open access
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Ip, W; Silva, JMF; Gaspar, H; Mitra, A; Patel, S; Rao, K; Chiesa, R; ... Qasim, W; + view all (2018) Multicenter phase 1/2 application of adenovirus-specific T cells in high-risk pediatric patients after allogeneic stem cell transplantation. Cytotherapy , 20 (6) pp. 830-838. 10.1016/j.jcyt.2018.03.040. Green open access
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Ito, Y; Carss, KJ; Duarte, ST; Hartley, T; Keren, B; Kurian, MA; Marey, I; ... Revel-Vilk, S; + view all (2018) De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures. American Journal of Human Genetics , 103 (1) pp. 144-153. 10.1016/j.ajhg.2018.06.001. Green open access
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Jacobsen, MC; Manunta, MDI; Pincott, ES; Fenton, M; Simpson, GL; Klein, NJ; Burch, M; (2018) Specific Immunity to Cytomegalovirus in Pediatric Cardiac Transplantation. Transplantation , 102 (9) pp. 1569-1575. 10.1097/TP.0000000000002157. Green open access
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James, CP; Bajaj-Elliott, M; Abujaber, R; Forya, F; Klein, N; David, AL; Hollox, EJ; (2018) Human beta defensin (HBD) gene copy number affects HBD2 protein levels: impact on cervical bactericidal immunity in pregnancy. European Journal of Human Genetics , 26 pp. 434-439. 10.1038/s41431-017-0061-7. Green open access
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Jones, S; Moreland, NJ; Zancolli, M; Raynes, J; Loh, JMS; Smeesters, PR; Sriskandan, S; ... Goldblatt, D; + view all (2018) Development of an Opsonophagocytic Killing Assay for Group A Streptococcus. Vaccine , 36 (26) pp. 3756-3763. 10.1016/j.vaccine.2018.05.056. Green open access
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Kanthimathinathan, HK; Peters, MJ; (2018) Focus on paediatrics 2018. Intensive Care Medicine , 44 (12) pp. 2267-2270. 10.1007/s00134-018-5421-4. Green open access
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Kelly, LE; Sinha, Y; Barker, CIS; Standing, JF; Offringa, M; (2018) Useful pharmacodynamic endpoints in children: selection, measurement, and next steps. Pediatric Research , 83 (6) pp. 1095-1103. 10.1038/pr.2018.38. Green open access
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Khan, R; Yasin, F; O'Neill, S; Cahalane, E; O'Shea, R; Browne, B; Cournane, J; ... Shannon, H; + view all (2018) DVD Versus Physiotherapist-Led Inhaler Education: A Randomised Controlled Trial. The Irish Medical Journal , 111 (2) , Article 695. Green open access
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Kimaro Mlacha, SZ; Warira, A; Gatakaa, H; Goldblatt, D; Scott, JAG; (2018) Outpacing the pneumococcus: Antibody dynamics in the first few days following pneumococcal capsular antigen stimulation. Scientific Reports , 8 , Article 15376. 10.1038/s41598-018-33735-x. Green open access
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Kipper, K; Barker, CIS; Standing, JF; Sharland, M; Johnston, A; (2018) Development of a novel multi-penicillin assay and assessment of the impact of analyte degradation: lessons for scavenged sampling in antimicrobial pharmacokinetic study design. Antimicrobial Agents and Chemotherapy , 62 (1) 10.1128/AAC.01540-17. Green open access
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Kityo, C; Szubert, A; Siika, A; Heyderman, R; Bwakura-Dangarembizi, M; Lugemwa, A; Mwaringa, S; ... Pett, S; + view all (2018) Raltegravir-intensified initial antiretroviral therapy in advanced HIV in Africa: a randomized controlled trial. PLoS Medicine , 15 (12) , Article e1002706. 10.1371/journal.. Green open access
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Knight, Gwenan M; Zimic, Mirko; Funk, Sebastian; Gilman, Robert H; Friedland, Jon S; Grandjean, Louis; (2018) The relative fitness of drug-resistant Mycobacterium tuberculosis: a modelling study of household transmission in Peru. Journal of the Royal Society Interface , 15 (143) , Article 20180025. 10.1098/rsif.2018.0025. Green open access
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Kothur, K; Bandodkar, S; Chu, S; Wienholt, L; Johnson, A; Barclay, P; Brogan, PA; ... Dale, RC; + view all (2018) An open-label trial of JAK 1/2 blockade in progressive IFIH1-associated neuroinflammation. Neurology , 90 (6) pp. 289-291. 10.1212/WNL.0000000000004921.

Kulkarni, N; Kantar, A; Costella, S; Ragazzo, V; Piacentini, G; Boner, A; O'Callaghan, C; (2018) Macrophage Phagocytosis and Allergen Avoidance in Children With Asthma. Frontiers in Pediatrics , 6 , Article 206. 10.3389/fped.2018.00206. Green open access
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Lacey, JRN; Kidel, C; van der Kaaij, JM; Brinkman, P; Gilbert-Kawai, ET; Grocott, MPW; Mythen, MG; ... Xtreme Everest 2 Research Group; + view all (2018) The Smell of Hypoxia: using an electronic nose at altitude and proof of concept of its role in the prediction and diagnosis of acute mountain sickness. Physiological Reports , 6 (17) , Article e13854. 10.14814/phy2.13854. Green open access
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Lau, C-I; Yánez, DC; Solanki, A; Papaioannou, E; Saldaña, JI; Crompton, T; (2018) Foxa1 and Foxa2 in thymic epithelial cells (TEC) regulate medullary TEC and regulatory T-cell maturation. Journal of Autoimmunity , 93 10.1016/j.jaut.2018.07.009. Green open access
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Lawless, D; Geier, CB; Farmer, JR; Lango, HA; Thwaites, D; Atschekzei, F; Brown, M; ... Savic, S; + view all (2018) Prevalence and clinical challenges among adults with primary immunodeficiency and recombination-activating gene deficiency. Journal of Allergy and Clinical Immunology , 141 (6) pp. 2303-2306. 10.1016/j.jaci.2018.02.007. Green open access
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Le Polain De Waroux, O; Edmunds, WJ; Takahashi, K; Ariyoshi, K; Mulholland, EK; Goldblatt, D; Choi, YH; ... Flasche, S; + view all (2018) Predicting the impact of pneumococcal conjugate vaccine programme options in Vietnam. Human Vaccines & Immunotherapeutics , 14 (8) pp. 1939-1947. 10.1080/21645515.2018.1467201. Green open access
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Lecce, F; Robertson, F; Rennie, A; Heuchan, A-M; Lister, P; Bhate, S; Bhattacharya, J; ... Ganesan, V; + view all (2018) Cross-sectional study of a UK cohort of neonatal vein of Galen malformation. Annals of Neurology , 84 (4) pp. 547-555. 10.1002/ana.25316. Green open access
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Lee, JJ; Wedow, R; Okbay, A; Kong, E; Maghzian, O; Zacher, M; Tuan, AN-V; ... Cesarini, D; + view all (2018) Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. Nature Genetics , 50 (8) pp. 1112-1121. 10.1038/s41588-018-0147-3. Green open access
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Lei, L; Muhammad, S; Al-Obaidi, M; Sebire, N; Cheng, IL; Eleftheriou, D; Brogan, P; (2018) Successful use of ofatumumab in two cases of early-onset juvenile SLE with thrombocytopenia caused by a mutation in protein kinase C δ. Pediatric Rheumatology , 16 (1) , Article 61. 10.1186/s12969-018-0278-1. Green open access
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Leon, LJ; Doyle, R; Diez-Benavente, E; Clark, TG; Klein, N; Stanier, P; Moore, GE; (2018) Enrichment of clinically relevant organisms in spontaneous preterm delivered placenta and reagent contamination across all clinical groups in a large UK pregnancy cohort. Applied and Environmental Microbiology , 84 (14) 10.1128/AEM.00483-18. Green open access
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Li, A; Yuen, VM; Goulay-Dufay, S; Sheng, Y; Standing, JF; Kwok, PCL; Leung, MKM; ... Irwin, MG; + view all (2018) Pharmacokinetic and pharmacodynamic study of intranasal and intravenous dexmedetomidine. British Journal of Anaesthesia , 120 (5) pp. 960-968. 10.1016/j.bja.2017.11.100. Green open access
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Lilleker, JB; Vencovsky, J; Wang, G; Wedderburn, LR; Diederichsen, LP; Schmidt, J; Oakley, P; ... all EuroMyositis contributors; + view all (2018) The EuroMyositis registry: an international collaborative tool to facilitate myositis research. Annals of the Rheumatic Diseases , 77 (1) pp. 30-39. 10.1136/annrheumdis-2017-211868. Green open access
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Longhurst, HJ; Dempster, J; Lorenzo, L; Buckland, M; Grigoriadou, S; Symons, C; Bethune, C; ... Garcez, T; + view all (2018) Real-world outcomes in hereditary angioedema: first experience from the Icatibant Outcome Survey in the United Kingdom. Allergy, Asthma & Clinical Immunology , 14 , Article 28. 10.1186/s13223-018-0253-x. Green open access
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Lucchini, G; Marsh, R; Gilmour, K; Worth, A; Nademi, Z; Rao, A; Booth, C; ... Rao, K; + view all (2018) Treatment dilemmas in asymptomatic children with primary hemophagocytic lymphohistiocytosis. Blood , 132 (19) pp. 2088-2096. 10.1182/blood-2018-01-827485. Green open access
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Lythgoe, H; Almeida, B; Bennett, J; Bhat, C; Bilkhu, A; Brennan, M; Deepak, S; ... Pain, CE; + view all (2018) Multi-centre national audit of juvenile localised scleroderma: describing current UK practice in disease assessment and management. Pediatric Rheumatology , 16 , Article 80. 10.1186/s12969-018-0295-0. Green open access
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M F Silva, J; Ladomenou, F; Carpenter, B; Chandra, S; Sedlacek, P; Formankova, R; Grandage, V; ... Veys, P; + view all (2018) Allogeneic hematopoietic stem cell transplantation for severe, refractory juvenile idiopathic arthritis. Blood Adv , 2 (7) pp. 777-786. 10.1182/bloodadvances.2017014449. Green open access
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Maccari, ME; Abolhassani, H; Aghamohammadi, A; Aiuti, A; Aleinikova, O; Bangs, C; Baris, S; ... Ehl, S; + view all (2018) Disease evolution and response to rapamycin in Activated Phosphoinositide 3-Kinase delta syndrome: the european society for immunodeficiencies-Activated Phosphoinositide 3-Kinase d syndrome registry. Frontiers in Immunology , 9 , Article 543. 10.3389/fimmu.2018.00543. Green open access
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Malbrain, MLNG; Van Regenmortel, N; Saugel, B; De Tavernier, B; Van Gaal, P-J; Joannes-Boyau, O; Teboul, J-L; ... Monnet, X; + view all (2018) Principles of fluid management and stewardship in septic shock: it is time to consider the four D's and the four phases of fluid therapy. Annals of Intensive Care , 8 , Article 66. 10.1186/s13613-018-0402-x. Green open access
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Mallewa, J; Szubert, AJ; Mugyenyi, P; Chidziva, E; Thomason, MJ; Chepkorir, P; Abongomera, G; ... REALITY trial team, .; + view all (2018) Effect of ready-to-use supplementary food on mortality in severely immunocompromised HIV-infected individuals in Africa initiating antiretroviral therapy (REALITY): an open-label, parallel-group, randomised controlled trial. The Lancet HIV , 5 (5) e231-e240. 10.1016/S2352-3018(18)30038-9. Green open access
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Martin, D; Peters, MJ; (2018) Might children rust? What are the risks of supplemental oxygen in acute illness. Archives of Disease in Childhood , 104 (2) pp. 106-107. 10.1136/archdischild-2018-315437. Green open access
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Martinón-Torres, F; Salas, A; Rivero-Calle, I; Cebey-López, M; Pardo-Seco, J; Herberg, JA; Boeddha, NP; ... EUCLIDS Consortium; + view all (2018) Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study. The Lancet Child & Adolescent Health , 2 (6) pp. 404-414. 10.1016/S2352-4642(18)30113-5. Green open access
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McErlane, F; Carrasco, R; Kearsley-Fleet, L; Baildam, EM; Wedderburn, LR; Foster, HE; Ioannou, Y; ... Hyrich, KL; + view all (2018) Growth patterns in early juvenile idiopathic arthritis: Results from the Childhood Arthritis Prospective Study (CAPS). Seminars in Arthritis and Rheumatism , 48 (1) pp. 53-60. 10.1016/j.semarthrit.2017.11.002. Green open access
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McWilliam, SJ; Antoine, DJ; Jorgensen, AL; Smyth, RL; Pirmohamed, M; (2018) Urinary Biomarkers of Aminoglycoside-Induced Nephrotoxicity in Cystic Fibrosis: Kidney Injury Molecule-1 and Neutrophil Gelatinase-Associated Lipocalin. Scientific Reports , 8 , Article 5094. 10.1038/s41598-018-23466-4. Green open access
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Mestek-Boukhibar, L; Clement, E; Jones, WD; Drury, S; Ocaka, L; Gagunashvili, A; Le Quesne Stabej, P; ... Williams, HJ; + view all (2018) Rapid Paediatric Sequencing (RaPS): comprehensive real-life workflow for rapid diagnosis of critically ill children. Journal of Medical Genetics , 55 (11) pp. 721-728. 10.1136/jmedgenet-2018-105396. Green open access
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Murphy, C; Weisskopf, A; Bohingamuwa, W; Adikari, G; Perera, N; Blinkhorn, J; Horton, M; ... Boivin, N; + view all (2018) Early agriculture in Sri Lanka: New Archaeobotanical analyses and radiocarbon dates from the early historic sites of Kirinda and Kantharodai (Kandarodai). Archaeological Research in Asia , 16 pp. 88-102. 10.1016/j.ara.2018.06.001. Green open access
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Nanthapisal, S; Eleftheriou, D; Gilmour, K; Leone, V; Ramnath, R; Omoyinmi, E; Hong, Y; ... Brogan, PA; + view all (2018) Cutaneous vasculitis and recurrent infection caused by deficiency in complement factor I. Frontiers in Immunology , 9 , Article 735. 10.3389/fimmu.2018.00735. Green open access
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Nellis, ME; Karam, O; Mauer, E; Cushing, MM; Davis, PJ; Steiner, ME; Tucci, M; ... Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) ne; + view all (2018) Platelet Transfusion Practices in Critically Ill Children. Critical Care Medicine , 46 (8) pp. 1309-1317. 10.1097/CCM.0000000000003192. Green open access
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Nicolas, A; Kenna, KP; Renton, AE; Ticozzi, N; Faghri, F; Chia, R; Dominov, JA; ... Landers, JE; + view all (2018) Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron , 97 (6) 1268-1283.e6. 10.1016/j.neuron.2018.02.027. Green open access
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O'Callaghan, C; Rutman, A; Williams, G; Kulkarni, N; Hayes, J; Hirst, RA; (2018) Ciliated conical epithelial cell protrusions point towards a diagnosis of primary ciliary dyskinesia. Respiratory Research , 19 , Article 125. 10.1186/s12931-018-0782-3. Green open access
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Odor, PM; Bampoe, S; Dushianthan, A; Bennett-Guerrero, E; Cro, S; Gan, TJ; Grocott, MPW; ... Burdett, E; + view all (2018) Perioperative administration of buffered versus non-buffered crystalloid intravenous fluid to improve outcomes following adult surgical procedures: a Cochrane systematic review. Perioperative Medicine , 7 , Article 27. 10.1186/s13741-018-0108-5. Green open access
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Ohl, K; Nickel, H; Moncrieffe, H; Klemm, P; Scheufen, A; Foell, D; Wixler, V; ... Tenbrock, K; + view all (2018) The transcription factor CREM drives an inflammatory phenotype of T cells in oligoarticular juvenile idiopathic arthritis. Pediatric Rheumatology , 16 , Article 39. 10.1186/s12969-018-0253-x. Green open access
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Ojal, J; Goldblatt, D; Tigoi, C; Scott, JAG; (2018) Effect of Maternally Derived Anti-protein and Anticapsular IgG Antibodies on the Rate of Acquisition of Nasopharyngeal Carriage of Pneumococcus in Newborns. Clinical Infectious Diseases , 66 (1) pp. 121-130. 10.1093/cid/cix742. Green open access
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Omoyinmi, E; Mohamoud, I; Gilmour, K; Brogan, PA; Eleftheriou, D; (2018) Cutaneous Vasculitis and Digital Ischaemia Caused by Heterozygous Gain-of-Function Mutation in C3. Frontiers in Immunology , 9 , Article 2524. 10.3389/fimmu.2018.02524. Green open access
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Padari, H; Metsvaht, T; Germovsek, E; Barker, CI; Kipper, K; Herodes, K; Standing, JF; ... Lutsar, I; + view all (2018) Pharmacokinetics of Penicillin G in Preterm and Term Neonates. Antimicrobial Agents and Chemotherapy , 62 (5) , Article e02238-17. 10.1128/AAC.02238-17. Green open access
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Pagel, C; Ramnarayan, P; Ray, S; Peters, MJ; (2018) Development and implementation of a real time statistical control method to identify the start and end of the winter surge in demand for paediatric intensive care. European Journal of Operational Research , 264 (3) pp. 847-858. 10.1016/j.ejor.2016.08.023. Green open access
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Pan, X; Collingwoode-Williams, T; Antley, A; Brenton, H; Congdon, B; Drewett, O; Gillies, MFP; ... Delacroix, S; + view all (2018) A study of professional awareness using immersive virtual reality: The responses of general practitioners to child safeguarding concerns. Frontiers in Robotics and AI , 5 , Article 80. 10.3389/frobt.2018.00080. Green open access
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Panchal, N; Booth, C; Cannons, JL; Schwartzberg, PL; (2018) X-Linked Lymphoproliferative Disease Type 1: A Clinical and Molecular Perspective. Frontiers in Immunology , 9 , Article 666. 10.3389/fimmu.2018.00666. Green open access
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Panchal, N; Houghton, B; Diez, B; Ghosh, S; Ricciardelli, I; Thrasher, AJ; Gaspar, HB; (2018) Transfer of gene corrected T cells corrects humoral and cytotoxic defects in X-linked lymphoproliferative disease (XLP1). Journal of Allergy and Clinical Immunology , 142 (1) 235-245.e6. 10.1016/j.jaci.2018.02.053. Green open access
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Papadopoulou, C; McCann, LJ; (2018) The Vasculopathy of Juvenile Dermatomyositis. Frontiers in Pediatrics , 6 , Article 284. 10.3389/fped.2018.00284. Green open access
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Parkes, JE; Rothwell, S; Oldroyd, A; Chinoy, H; Lamb, JA; Lundberg, IE; Miller, FW; ... Betteridge, ZE; + view all (2018) Genetic background may contribute to the latitude-dependent prevalence of dermatomyositis and anti-TIF1-γ autoantibodies in adult patients with myositis. Arthritis Research and Therapy , 20 , Article 117. 10.1186/s13075-018-1617-9. Green open access
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Peters, MJ; Agbeko, R; Davis, P; Klein, N; Zenasi, Z; Jones, A; Mackerness, C; ... SCARF study investigators and the Pediatric Intensive Care Socie; + view all (2018) Randomized Study of Early Continuous Positive Airways Pressure in Acute Respiratory Failure in Children With Impaired Immunity (SCARF) ISRCTN82853500. Pediatric Critical Care Medicine , 19 (10) pp. 939-948. 10.1097/PCC.0000000000001683. Green open access
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Peters, MJ; Jones, GA; Eaton, S; Wiley, D; Ray, S; (2018) Risks and benefits of oxygen therapy. Journal of Inherited Metabolic Disease , 41 (5) pp. 757-759. 10.1007/s10545-018-0208-x. Green open access
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Peters, MJ; Jones, GAL; Wiley, D; Wulff, J; Ramnarayan, P; Ray, S; Inwald, D; ... Oxy-PICU Investigators for the Paediatric Intensive Care Society, .; + view all (2018) Conservative versus liberal oxygenation targets in critically ill children: the randomised multiple-centre pilot Oxy-PICU trial. Intensive Care Medicine , 44 (8) pp. 1240-1248. 10.1007/s00134-018-5232-7. Green open access
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Pike, KC; akhbari, M; Kneale, D; Harris, K; (2018) Interventions for autumn exacerbations of asthma in children. Cochrane Database of Systematic Reviews , 2018 (3) , Article CD012393. 10.1002/14651858.CD012393.pub2. Green open access
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Pike, KC; Akhbari, M; Kneale, D; Harris, KM; (2018) Interventions for autumn exacerbations of asthma in children. Paediatric Respiratory Reviews , 27 pp. 37-39. 10.1016/j.prrv.2018.03.004. Green open access
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Poletti, V; Charrier, S; Corre, G; Gjata, B; Vignaud, A; Zhang, F; Rothe, M; ... Mavilio, F; + view all (2018) Preclinical Development of a Lentiviral Vector for Gene Therapy of X-Linked Severe Combined Immunodeficiency. Molecular Therapy - Methods and Clinical Development , 9 pp. 257-269. 10.1016/j.omtm.2018.03.002. Green open access
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Rafiq, NK; Lachmann, H; Joensen, F; Herlin, T; Brogan, PA; (2018) Tocilizumab for the Treatment of Mevalonate Kinase Deficiency. Case Reports in Pediatrics , 2018 , Article 3514645. 10.1155/2018/3514645. Green open access
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Raman, S; Chentouf, L; DeVile, C; Peters, MJ; Rahman, S; (2018) Near infrared spectroscopy with a vascular occlusion test as a biomarker in children with mitochondrial and other neuro-genetic disorders. PLoS One , 13 (7) , Article e0199756. 10.1371/journal.pone.0199756. Green open access
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Ramnarayan, P; Lister, P; Dominguez, T; Habibi, P; Edmonds, N; Canter, RR; Wulff, J; ... United Kingdom Paediatric Intensive Care Society Study Group (PI; + view all (2018) FIRST-line support for Assistance in Breathing in Children (FIRST-ABC): a multicentre pilot randomised controlled trial of high-flow nasal cannula therapy versus continuous positive airway pressure in paediatric critical care. Critical Care , 22 (1) , Article 144. 10.1186/s13054-018-2080-3. Green open access
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Ray, S; Rogers, L; Brown, KL; Peters, MJ; (2018) The Effect of Acetaminophen on Temperature in Critically Ill Children: A Retrospective Analysis of Over 50,000 Doses. Pediatric Critical Care Medicine , 19 (3) pp. 204-209. 10.1097/PCC.0000000000001426. Green open access
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Rijpkema, S; Hockley, J; Logan, A; Rigsby, P; Atkinson, E; Jin, C; Goldblatt, D; ... anti-Vi IgG working group; + view all (2018) Establishment of the first International Standard for human anti-typhoid capsular Vi polysaccharide IgG. Biologicals , 56 pp. 29-38. 10.1016/j.biologicals.2018.09.001. Green open access
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Rivers, E; Worth, A; Thrasher, AJ; Burns, SO; (2018) Bleeding and splenectomy in Wiskott-Aldrich syndrome: A single-centre experience. [Letter]. The Journal of Allergy and Clinical Immunology: In Practice 10.1016/j.jaip.2018.07.009. (In press). Green open access
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Robinson, PD; Latzin, P; Ramsey, KA; Stanojevic, S; Aurora, P; Davis, SD; Gappa, M; ... Ratjen, F; + view all (2018) Preschool Multiple-Breath Washout Testing An Official American Thoracic Society Technical Statement: Executive Summary. American Journal of Respiratory and Critical Care Medicine , 197 (5) pp. 557-572. 10.1164/rccm.201801-0074ST. Green open access
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Ross, S; Cheung, M; Lau, C-I; Sebire, N; Burch, M; Kilbride, P; Fuller, B; ... Crompton, T; + view all (2018) Transplanted human thymus slices induce and support T‐cell development in mice after cryopreservation. European Journal of Immunology , 48 (4) pp. 716-719. 10.1002/eji.201747193. Green open access
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Rosser, EC; Lom, H; Bending, D; Duurland, CL; Bajaj-Elliott, M; Wedderburn, LR; (2018) Brief Report: Innate lymphoid cells and T-cells contribute to the IL-17A signature detected in the synovial fluid of patients with Juvenile Idiopathic Arthritis. Arthritis and Rheumatology 10.1002/art.40731. (In press). Green open access
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Ruis, C; Brown, L-AK; Roy, S; Atkinson, C; Williams, R; Burns, SO; Yara-Romero, E; ... Lowe, DM; + view all (2018) Mutagenesis in Norovirus in Response to Favipiravir Treatment. New England Journal of Medicine , 379 (22) pp. 2173-2176. 10.1056/NEJMc1806941. Green open access
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Sage, E; Davies, A; Kolluri, K; Patrick, S; Weil, B; Rego, RVTP; Edwards, A; ... Janes, SM; + view all (2018) Targeted stem cells expressing TRAIL as a therapy for lung Cancer TACTICAL: a phase I/II trial. Lung Cancer , 115 (Supp. 1) S87-S87. 10.1016/S0169-5002(18)30222-8. Green open access
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Sanghani-Kerai, A; McCreary, D; Lancashire, H; Osagie, L; Coathup, M; Blunn, G; (2018) Stem Cell Interventions for Bone Healing: Fractures and Osteoporosis. Current Stem Cell Research & Therapy , 13 (5) pp. 369-377. 10.2174/1574888X13666180410160511. Green open access
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Seguin, M; Dodds, C; Mugweni, E; McDaid, L; Flowers, P; Wayal, S; Zomer, E; ... Burns, F; + view all (2018) Self-sampling kits to increase HIV testing among black Africans in the UK: the HAUS mixed-methods study. Health Technology Assessment , 22 (22) 10.3310/hta22220. Green open access
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Seidel, MG; Böhm, K; Dogu, F; Worth, A; Thrasher, A; Florkin, B; İkincioğulları, A; ... Gennery, AR; + view all (2018) Treatment of Severe Forms of LPS-Responsive Beige-like Anchor Protein (LRBA) Deficiency by Allogeneic Hematopoietic Stem Cell Transplantation. Journal of Allergy and Clinical Immunology , 141 (2) 770-775.e1. 10.1016/j.jaci.2017.04.023. Green open access
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Shillitoe, B; Bangs, C; Guzman, D; Gennery, AR; Longhurst, HJ; Slatter, M; Edgar, DM; ... Buckland, M; + view all (2018) The United Kingdom Primary Immune Deficiency (UKPID) registry 2012 to 2017. Clinical and Experimental Immunology , 192 (3) pp. 284-291. 10.1111/cei.13125. Green open access
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Wood, D; Geoghegan, S; Ramnarayan, P; Davis, PJ; Pappachan, JV; Goodwin, S; Wray, J; (2018) Eliciting the experiences of the adolescent-parent dyad following critical care admission: a pilot study. European Journal of Pediatrics , 177 (5) pp. 747-752. 10.1007/s00431-018-3117-y. Green open access
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Wu, Q; Wedderburn, LR; McCann, LJ; (2018) Juvenile dermatomyositis: Latest advances. Best Practice & Research: Clinical Rheumatology , 31 (4) pp. 535-557. 10.1016/j.berh.2017.12.003. Green open access
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Xia, DQH; Qureshi, A; Bhakta, S; Keep, NH; (2018) Mutation studies of the gene encoding YuiC, a stationary phase survival protein in Bacillus subtilis. Malaysian Journal of Microbiology , 14 (6) pp. 444-451. 10.21161/mjm.1461801. Green open access
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Yebra, G; Frampton, D; Gallo Cassarino, T; Raffle, J; Hubb, J; Ferns, RB; Waters, L; ... ICONIC Consortium, .; + view all (2018) A high HIV-1 strain variability in London, UK, revealed by full-genome analysis: Results from the ICONIC project. PLoS One , 13 (2) , Article e0192081. 10.1371/journal.pone.0192081. Green open access