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Leukocyte adhesion deficiency-I: A comprehensive review of all published cases

Almarza Novoa, E; Kasbekar, S; Thrasher, AJ; Kohn, DB; Sevilla, J; Nguyen, T; Schwartz, JD; (2018) Leukocyte adhesion deficiency-I: A comprehensive review of all published cases. Journal of Allergy and Clinical Immunology: In Practice , 6 (4) 1418-1420.e10. 10.1016/j.jaip.2017.12.008. Green open access

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Abstract

Leukocyte adhesion deficiency-I (LAD-I) is a rare, serious disorder with severity determined by defective CD18 expression. LAD-I is characterized by umbilical complications, granulocytosis, and diverse infections. Severe LAD-I is frequently fatal before the age of 2 years without allogeneic transplant. We identified 323 cases published between 1975 and 2017.

Type: Article
Title: Leukocyte adhesion deficiency-I: A comprehensive review of all published cases
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.jaip.2017.12.008
Publisher version: http://dx.doi.org/10.1016/j.jaip.2017.12.008
Language: English
Additional information: Copyright © 2017 The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology. This is an open access article under the CC-BY NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Infection, Immunity and Inflammation Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10042078
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