UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Browse by UCL Departments and Centres

Group by: Author | Type
Number of items: 118.

Article

Acman, M; Van Dorp, L; Santini, JM; Balloux, F; (2020) Large-scale network analysis captures biological features of bacterial plasmids. Nature Communications , 11 , Article 2452. 10.1038/s41467-020-16282-w. Green open access
file

Al-Shayeb, B; Sachdeva, R; Chen, L-X; Ward, F; Munk, P; Devoto, A; Castelle, CJ; ... Banfield, JF; + view all (2020) Clades of huge phages from across Earth's ecosystems. Nature , 578 pp. 425-431. 10.1038/s41586-020-2007-4. Green open access
file

Allison, TM; Barran, P; Benesch, JLP; Cianferani, S; Degiacomi, MT; Gabelica, V; Grandori, R; ... Thalassinos, K; + view all (2020) Software Requirements for the Analysis and Interpretation of Native Ion Mobility Mass Spectrometry Data. Analytical Chemistry , 92 (16) pp. 10881-10890. 10.1021/acs.analchem.9b05792. Green open access
file

Allison, TM; Barran, P; Cianférani, S; Degiacomi, MT; Gabelica, V; Grandori, R; Marklund, EG; ... Benesch, JLP; + view all (2020) Computational Strategies and Challenges for Using Native Ion Mobility Mass Spectrometry in Biophysics and Structural Biology. Analytical Chemistry , 92 (16) pp. 10872-10880. 10.1021/acs.analchem.9b05791. Green open access
file

ASLAN, ES; WHITE, KN; SYED, BA; SRAI, KS; EVANS, RW; (2020) Expression of soluble, active, fluorescently tagged hephaestin in COS and CHO cell lines. Turkish Journal of Biology , 44 (6) pp. 393-405. 10.3906/biy-2005-39. Green open access
file

Atherton, J; Hummel, JJ; Olieric, N; Locke, J; Peña, A; Rosenfeld, SS; Steinmetz, MO; ... Moores, CA; + view all (2020) The mechanism of kinesin inhibition by kinesin binding protein. eLife , 9 , Article e61481. 10.7554/eLife.61481. (In press). Green open access
file

Bancroft, PJ; Turapov, O; Jagatia, H; Arnvig, KB; Mukamolova, GV; Green, J; (2020) Coupling of Peptidoglycan Synthesis to Central Metabolism in Mycobacteria: Post-transcriptional Control of CwlM by Aconitase. Cell Reports , 32 (13) , Article 108209. 10.1016/j.celrep.2020.108209. Green open access
file

Baxter, M; Voronkov, M; Poolman, T; Galli, G; Pinali, C; Goosey, L; Knight, A; ... Ray, D; + view all (2020) Cardiac mitochondrial function depends on BUD23 mediated ribosome programming. eLife , 9 , Article e50705. 10.7554/eLife.50705. Green open access
file

Bellany, F; Tsuchiya, Y; Tran, TM; Chan, AWE; Allan, H; Gout, I; Tabor, AB; (2020) Design and synthesis of Coenzyme A analogues as Aurora kinase A inhibitors: An exploration of the roles of the pyrophosphate and pantetheine moieties. Bioorganic & Medicinal Chemistry , 28 (22) , Article 115740. 10.1016/j.bmc.2020.115740. Green open access
filefile

Ben Bdira, F; Waudby, CA; Volkov, AN; Schröder, SP; AB, E; Codée, JDC; Overkleeft, HS; ... Ubbink, M; + view all (2020) Dynamics of Ligand Binding to a Rigid Glycosidase. Angewandte Chemie 10.1002/ange.202003236. Green open access
file

Blum, M; Chang, H-Y; Chuguransky, S; Grego, T; Kandasaamy, S; Mitchell, A; Nuka, G; ... Finn, RD; + view all (2020) The InterPro protein families and domains database: 20 years on. Nucleic Acids Research 10.1093/nar/gkaa977. (In press). Green open access
file

Briant, K; Redlingshöfer, L; Brodsky, FM; (2020) Clathrin's life beyond 40: Connecting biochemistry with physiology and disease. Current Opinion in Cell Biology , 65 pp. 141-149. 10.1016/j.ceb.2020.06.004. Green open access
file

Britt, HM; Prakash, AS; Appleby, S; Mosely, JA; Sanderson, JM; (2020) Lysis of membrane lipids promoted by small organic molecules: Reactivity depends on structure but not lipophilicity. Science Advances , 6 (17) , Article eaaz8598. 10.1126/sciadv.aaz8598. Green open access
file

Brodsky, FM; Parham, P; (2020) In Memoriam: Peter Hartmann (1946-2020), publisher, colleague and friend. HLA: Immune Response Genetics , 96 (6) pp. 665-666. 10.1111/tan.14089. Green open access
file

Brodsky, FM; Perez, F; (2020) Looking back to traffic forward: A tribute to Thomas Kreis (1952‐1998) and his inspiration. Traffic , 21 (1) pp. 186-188. 10.1111/tra.12697. Green open access
file

Brodsky, FM; Stow, JL; (2020) Editorial overview: Membrane traffic in the time of COVID-19. Current Opinion in Cell Biology , 65 iii-v. 10.1016/j.ceb.2020.09.003. Green open access
file

Bultitude, WP; Schellekens, J; Szydlo, RM; Anthias, C; Cooley, SA; Miller, JS; Weisdorf, DJ; ... Marsh, SGE; + view all (2020) Presence of donor-encoded centromeric KIR B content increases the risk of infectious mortality in recipients of myeloablative, T-cell deplete, HLA-matched HCT to treat AML. Bone Marrow Transplantation , 55 pp. 1975-1984. 10.1038/s41409-020-0858-9. Green open access
file

Cackett, G; Matelska, D; Sýkora, M; Portugal, R; Malecki, M; Bähler, J; Dixon, L; (2020) The African Swine Fever Virus Transcriptome. Journal of Virology , 94 (9) , Article e00119-20. 10.1128/JVI.00119-20. Green open access
file

Cackett, G; Sýkora, M; Werner, F; (2020) Transcriptome view of a killer: African swine fever virus. Biochemical Society Transactions 10.1042/BST20191108. (In press). Green open access
file

Capitini, C; Fani, G; Vega, MV; Penco, A; Canale, C; Cabrita, LD; Calamai, M; ... Chiti, F; + view all (2020) Full-length TDP-43 and its C-terminal domain form filamentsin vitrohaving non-amyloid properties. Amyloid , 28 (1) pp. 56-65. 10.1080/13506129.2020.1826425. Green open access
file

Casamento, A; Boucrot, E; (2020) Molecular mechanism of Fast Endophilin-Mediated Endocytosis. The Biochemical Journal , 477 (12) pp. 2327-2345. 10.1042/BCJ20190342. Green open access
file

Cassaignau, AME; Cabrita, LD; Christodoulou, J; (2020) How Does the Ribosome Fold the Proteome? Annual Review of Biochemistry , 89 pp. 389-415. 10.1146/annurev-biochem-062917-012226.

Conole, D; Chou, Y-T; Patsiarika, A; Nwabo, V; Dinnitriou, E; Soudy, C; Mota, F; ... Selwood, DL; + view all (2020) Discovery of a novel fluorescent chemical probe suitable for evaluation of neuropilin‐1 binding of small molecules. Drug Development Research , 81 (4) pp. 491-500. 10.1002/ddr.21641. Green open access
file

Csibra, E; Renders, M; Pinheiro, V; (2020) Bacterial cell display as a robust and versatile platform for the engineering of low affinity ligands and enzymes. ChemBiochem , 21 (19) pp. 2844-2853. 10.1002/cbic.202000203. Green open access
file

Das, S; Scholes, HM; Sen, N; Orengo, C; (2020) CATH functional families predict functional sites in proteins. Bioinformatics 10.1093/bioinformatics/btaa937. (In press). Green open access
file

Edinburgh, RM; Bradley, HE; Abdullah, N-F; Robinson, SL; Chrzanowski-Smith, OJ; Walhin, J-P; Joanisse, S; ... Gonzalez, JT; + view all (2020) Lipid metabolism links nutrient-exercise timing to insulin sensitivity in men classified as overweight or obese. The Journal of Clinical Endrocrinology & Metabolism , 105 (3) pp. 660-676. 10.1210/clinem/dgz104. Green open access
file

Edwards, SJL; Santini, JM; (2020) Anthroponotic risk of SARS-CoV-2, precautionary mitigation, and outbreak management. The Lancet Microbe 10.1016/s2666-5247(20)30086-0. (In press). Green open access
file

Eldrid, C; O'Connor, E; Thalassinos, K; (2020) Concentration‐dependent coulombic effects in travelling wave ion mobility spectrometry collision cross section calibration. Rapid Communications in Mass Spectrometry , 34 (S4) , Article e8613. 10.1002/rcm.8613. Green open access
file

Eldrid, C; Thalassinos, K; (2020) Developments in tandem ion mobility mass spectrometry. Biochemical Society Transactions , 48 (6) pp. 2457-2466. 10.1042/BST20190788. Green open access
file

Fare, C; Yuan, L; Cordon-Preciado, V; Michels, JJ; Bearpark, MJ; Rich, P; van Thor, JJ; (2020) Radical-Triggered Reaction Mechanism of the Green-to-Red Photoconversion of EosFP. The Journal of Physical Chemistry B , 124 (36) pp. 7765-7778. 10.1021/acs.jpcb.0c04587. Green open access
file

Faull, SV; Elliston, ELK; Gooptu, B; Jagger, AM; Aldobiyan, I; Redzej, A; Badaoui, M; ... Lomas, DA; + view all (2020) The structural basis for Z α₁-antitrypsin polymerization in the liver. Science Advances , 6 (43) , Article eabc1370. 10.1126/sciadv.abc1370. Green open access
file

Giansily‐Blaizot, M; Rallapalli, PM; Perkins, SJ; Kemball‐Cook, G; Hampshire, DJ; Gomez, K; Ludlam, CA; (2020) The EAHAD blood coagulation factor VII variant database. Human Mutation 10.1002/humu.24025. (In press). Green open access
file

Gould, GW; Brodsky, F; Bryant, NJ; (2020) Building GLUT4 vesilces: CHC22 clathrin's human touch. Trends in Cell Biology 10.1016/j.tcb.2020.05.007. (In press). Green open access
file

Gradeci, D; Bove, A; Charras, G; Lowe, AR; Banerjee, S; (2020) Single-cell approaches to cell competition: high-throughput imaging, machine learning and simulations. Seminars in Cancer Biology , 63 pp. 60-68. 10.1016/j.semcancer.2019.05.007. Green open access
file

Greenwood, SOR; Chan, AWE; Hansen, DF; Marson, CM; (2020) Potent non-hydroxamate inhibitors of histone deacetylase-8: Role and scope of an isoindolin-2-yl linker with an α-amino amide as the zinc-binding unit. Bioorganic & Medicinal Chemistry Letters , 30 (5) , Article 126926. 10.1016/j.bmcl.2019.126926. Green open access
file

Greig, Joshua; Bulgakova, Natalia A; (2020) Interplay between actomyosin and E-cadherin dynamics regulates cell shape in the Drosophila embryonic epidermis. Journal of Cell Science , 133 (15) , Article jcs242321. 10.1242/jcs.242321. Green open access
file

Gruszka, DT; Xie, S; Kimura, H; Yardimci, H; (2020) Single-molecule imaging reveals control of parental histone recycling by free histones during DNA replication. Science Advances , 6 (38) , Article eabc0330. 10.1126/sciadv.abc0330. Green open access
file

Harris, SE; Poolman, TM; Arvaniti, A; Cox, RD; Gathercole, LL; Tomlinson, JW; (2020) The American lifestyle-induced obesity syndrome diet in male and female rodents recapitulates the clinical and transcriptomic features of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. American Journal of Physiology - Gastrointestinal and Liver Physiology , 319 (3) G345-G360. 10.1152/ajpgi.00055.2020. Green open access
file

Hartley, AM; Meunier, B; Pinotsis, N; Maréchal, A; (2020) Rcf2 revealed in cryo-EM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes. Proceedings of the National Academy of Sciences 10.1073/pnas.1920612117. (In press). Green open access
file

Heifetz, A; James, T; Southey, M; Morao, I; Fedorov, DG; Bodkin, MJ; Townsend-Nicholson, A; (2020) Analyzing GPCR-Ligand Interactions with the Fragment Molecular Orbital (FMO) Method. Methods in Molecular Biology , 2114 pp. 163-175. 10.1007/978-1-0716-0282-9_11. Green open access
file

Heifetz, A; Morao, I; Babu, MM; James, T; Southey, MWY; Fedorov, DG; Aldeghi, M; ... Townsend-Nicholson, A; + view all (2020) Characterising Inter-helical Interactions of G Protein-Coupled Receptors with the Fragment Molecular Orbital Method. Journal of Chemical Theory and Computation 10.1021/acs.jctc.9b01136. (In press). Green open access
file

Heifetz, A; Sladek, V; Townsend-Nicholson, A; Fedorov, DG; (2020) Characterizing Protein-Protein Interactions with the Fragment Molecular Orbital Method. Methods in Molecular Biology , 2114 pp. 187-205. 10.1007/978-1-0716-0282-9_13. Green open access
file

Heifetz, A; Townsend-Nicholson, A; (2020) Characterizing Rhodopsin-Arrestin Interactions with the Fragment Molecular Orbital (FMO) Method. Methods in Molecular Biology , 2114 pp. 177-186. 10.1007/978-1-0716-0282-9_12. Green open access
file

Hunter, AL; Pelekanou, CE; Adamson, A; Downton, P; Barron, NJ; Cornfield, T; Poolman, TM; ... Ray, DW; + view all (2020) Nuclear receptor REVERBα is a state-dependent regulator of liver energy metabolism. Proceedings of the National Academy of Sciences of the United States of America 10.1073/pnas.2005330117. (In press). Green open access
file

Ireland, S; Martin, A; (2020) atomium - A Python structure parser. Bioinformatics , 36 (9) pp. 2750-2754. 10.1093/bioinformatics/btaa072. Green open access
file

Jagger, AM; Waudby, CA; Irving, JA; Christodoulou, J; Lomas, DA; (2020) High-resolution ex vivo NMR spectroscopy of human Z α1-antitrypsin. Nature Communications , 11 , Article 6371. 10.1038/s41467-020-20147-7. Green open access
file

Juárez-Jiménez, J; Gupta, AA; Karunanithy, G; Mey, ASJS; Georgiou, C; Ioannidis, H; De Simone, A; ... Michel, J; + view all (2020) Dynamic design: manipulation of millisecond timescale motions on the energy landscape of cyclophilin A. Chemical Science , 11 (10) pp. 2670-2680. 10.1039/c9sc04696h. Green open access
file

Kadkhodayi-Kholghi, N; Bhatt, JS; Gor, J; McDermott, LC; Gale, DP; Perkins, SJ; (2020) The solution structure of the complement deregulator FHR5 reveals a compact dimer and provides new insights into CFHR5 nephropathy. Journal of Biological Chemistry , 295 (48) pp. 16342-16358. 10.1074/jbc.ra120.015132. Green open access
file

Karunanithy, G; Reinstein, J; Hansen, DF; (2020) Multi-Quantum Chemical Exchange Saturation Transfer NMR to Quantify Symmetrical Exchange: Application to Rotational Dynamics of the Guanidinium Group in Arginine Side Chains. The Journal of Physical Chemistry Letters 10.1021/acs.jpclett.0c01322. (In press). Green open access
file

Katan, M; Cockcroft, S; (2020) Phospholipase C families: Common themes and versatility in physiology and pathology. Progress in Lipid Research , 80 , Article 101065. 10.1016/j.plipres.2020.101065. Green open access
file

Katan, M; Cockcroft, S; (2020) Phosphatidylinositol(4,5)bisphosphate: diverse functions at the plasma membrane. Essays in Biochemistry , Article EBC20200041. 10.1042/EBC20200041. (In press). Green open access
file

Kiataramgul, A; Maneenin, S; Purton, S; Areechon, N; Hirono, I; Brocklehurst, TW; Unajak, S; (2020) An oral delivery system for controlling white spot syndrome virus infection in shrimp using transgenic microalgae. Aquaculture , 521 , Article 735022. 10.1016/j.aquaculture.2020.735022. Green open access
file

Kitchen, GB; Cunningham, PS; Poolman, TM; Iqbal, M; Maidstone, R; Baxter, M; Bagnall, J; ... Ray, DW; + view all (2020) The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia. Proceedings of the National Academy of Sciences of the United States of America , 117 (3) pp. 1543-1551. 10.1073/pnas.1915932117. Green open access
file

Kose, Hazal B; Xie, Sherry; Cameron, George; Strycharska, Melania S; Yardimci, Hasan; (2020) Duplex DNA engagement and RPA oppositely regulate the DNA-unwinding rate of CMG helicase. Nature Communications , 11 , Article 3713. 10.1038/s41467-020-17443-7. Green open access
file

Kramm, K; Schröder, T; Gouge, J; Vera, AM; Gupta, K; Heiss, FB; Liedl, T; ... Grohmann, D; + view all (2020) DNA origami-based single-molecule force spectroscopy elucidates RNA Polymerase III pre-initiation complex stability. Nature Communications , 11 , Article 2828. 10.1038/s41467-020-16702-x. Green open access
file

Lam, SD; Bordin, N; Waman, VP; Scholes, HM; Ashford, P; Sen, N; van Dorp, L; ... Orengo, CA; + view all (2020) SARS-CoV-2 spike protein predicted to form complexes with host receptor protein orthologues from a broad range of mammals. Scientific Reports , 10 , Article 16471. 10.1038/s41598-020-71936-5. Green open access
file

Larrea-Alvarez, M; Purton, S; (2020) Multigenic engineering of the chloroplast genome in the green alga Chlamydomonas reinhardtii. Microbiology 10.1099/mic.0.000910. Green open access
file

Laskowski, RA; Stephenson, JD; Sillitoe, I; Orengo, CA; Thornton, JM; (2020) VarSite: disease variants and protein structure. Protein Science , 29 (1) pp. 111-119. 10.1002/pro.3746. Green open access
file

Leitner, Alexander; Bonvin, Alexandre MJJ; Borchers, Christoph H; Chalkley, Robert J; Chamot-Rooke, Julia; Combe, Colin W; Cox, Jürgen; ... Rappsilber, Juri; + view all (2020) Toward Increased Reliability, Transparency, and Accessibility in Cross-linking Mass Spectrometry. Structure , 28 (11) pp. 1259-1268. 10.1016/j.str.2020.09.011. Green open access
file

Lesne, J; Locard-Paulet, M; Parra, J; Zivković, D; Menneteau, T; Bousquet, M-P; Burlet-Schiltz, O; (2020) Conformational maps of human 20S proteasomes reveal PA28- and immuno-dependent inter-ring crosstalks. Nature Communications , 11 , Article 6140. 10.1038/s41467-020-19934-z. Green open access
file

Levray, YS; Berhe, AD; Osborne, AR; (2020) Use of split-dihydrofolate reductase for the detection of protein-protein interactions and simultaneous selection of multiple plasmids in Plasmodium falciparum. Molecular and Biochemical Parasitology , 238 , Article 111292. 10.1016/j.molbiopara.2020.111292. Green open access
file

Lima, NC; Atkinson, E; Bunney, TD; Katan, M; Huang, PH; (2020) Targeting the Src Pathway Enhances the Efficacy of Selective FGFR Inhibitors in Urothelial Cancers with FGFR3 Alterations. International Journal of Molecular Sciences , 21 (9) , Article 3214. 10.3390/ijms21093214. Green open access
file

Liu, Y; Bunney, TD; Khosa, S; Macé, K; Beckenbauer, K; Askwith, T; Maslen, S; ... Katan, M; + view all (2020) Structural insights and activating mutations in diverse pathologies define mechanisms of deregulation for phospholipase C gamma enzymes. EBioMedicine , 51 , Article 102607. 10.1016/j.ebiom.2019.102607. Green open access
file

Makrinou, E; Drong, AW; Christopoulos, G; Lerner, A; Chapa-Chorda, I; Karaderi, T; Lavery, S; ... Franks, S; + view all (2020) Genome-wide methylation profiling in granulosa lutein cells of women with polycystic ovary syndrome (PCOS). Molecular and Cellular Endocrinology , 500 , Article 110611. 10.1016/j.mce.2019.110611. Green open access
file

Manka, SW; Moores, CA; (2020) Pseudo-repeats in doublecortin make distinct mechanistic contributions to microtubule regulation. EMBO Reports , Article e51534. 10.15252/embr.202051534. Green open access
file

Maréchal, A; Xu, J-Y; Genko, N; Hartley, AM; Haraux, F; Meunier, B; Rich, PR; (2020) A common coupling mechanism for A-type heme-copper oxidases from bacteria to mitochondria. Proceedings of the National Academy of Sciences 10.1073/pnas.2001572117. (In press). Green open access
file

Martin-Nalda, A; Fortuny, C; Rey, L; Bunney, TD; Alsina, L; Esteve-Sole, A; Bull, D; ... Arostegui, J; + view all (2020) Severe Autoinflammatory Manifestations and Antibody Deficiency Due to Novel Hypermorphic PLCG2 Mutations. Journal of Clinical Immunology 10.1007/s10875-020-00794-7. (In press). Green open access
file

McCarthy, S; Robinson, J; Thalassinos, K; Tabor, AB; (2020) A Chemical Biology Approach to Probing the Folding Pathways of the Inhibitory Cystine Knot (ICK) Peptide ProTx-II. Frontiers in Chemistry , 8 , Article 228. 10.3389/fchem.2020.00228. Green open access
file

McVey, JH; Rallapalli, PM; Kemball-Cook, G; Hampshire, DJ; Giansily-Blaizot, M; Gomez, K; Perkins, SJ; (2020) The European Association for Haemophilia and Allied Disorders (EAHAD) Coagulation Factor Variant Databases: Important resources for haemostasis clinicians and researchers. Haemophilia , 26 (2) pp. 306-313. 10.1111/hae.13947. Green open access
filefile

Meir, A; Macé, K; Lukoyanova, N; Chetrit, D; Hospenthal, MK; Redzej, A; Roy, C; (2020) Mechanism of effector capture and delivery by the type IV secretion system from Legionella pneumophila. Nature Communications , 11 , Article 2864. 10.1038/s41467-020-16681-z. Green open access
file

Mitropoulou, AN; Ceska, T; Heads, JT; Beavil, AJ; Henry, AJ; McDonnell, JM; Sutton, BJ; (2020) Engineering the Fab fragment of the anti-IgE omalizumab to prevent Fab crystallization and permit IgE-Fc complex crystallization. Acta Crystallographica Section F: Structural Biology Communications , 76 (3) pp. 116-129. 10.1107/s2053230x20001466. Green open access
file

Modi, T; Gervais, D; Smith, S; Miller, J; Subramaniam, S; Thalassinos, K; Shepherd, A; (2020) Characterization of the UK anthrax vaccine and human immunogenicity. Human Vaccines & Immunotherapeutics 10.1080/21645515.2020.1799668. (In press). Green open access
file

Orengo, C; Velankar, S; Wodak, S; Zoete, V; Bonvin, AMJJ; Elofsson, A; Feenstra, KA; ... Schneider, B; + view all (2020) A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community). F1000Research , 9 , Article 278. 10.12688/f1000research.20559.1. Green open access
file

Ozuna, A; Liberto, D; Joyce, RM; Arnvig, KB; Nobeli, I; (2020) baerhunter: An R package for the discovery and analysis of expressed non-coding regions in bacterial RNA-seq data. Bioinformatics , 36 (3) pp. 966-969. 10.1093/bioinformatics/btz643. Green open access
file

Patel, VM; Flanagan, CE; Martins, M; Jones, CL; Butler, RM; Woollard, WJ; Bakr, FS; ... Mitchell, TJ; + view all (2020) Frequent and Persistent PLCG1 Mutations in Sezary Cells Directly Enhance PLC gamma 1 Activity and Stimulate NF kappa B, AP-1, and NFAT Signaling. Journal of Investigative Dermatology , 140 (2) pp. 380-389. 10.1016/j.jid.2019.07.693. Green open access
file

PDBe-KB consortium; (2020) PDBe-KB: a community-driven resource for structural and functional annotations. Nucleic Acids Research , 48 (D1) D344-D353. 10.1093/nar/gkz853. Green open access
file

Peña, A; Sweeney, A; Cook, AD; Topf, M; Moores, CA; (2020) Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy. Structure 10.1016/j.str.2020.01.013. (In press). Green open access
file

Perkins, S; (2020) Genetic and protein structural evaluation of atypical haemolytic uremic syndrome and C3 glomerulopathy. Advances in Chronic Kidney Disease , 27 (2) pp. 120-127. 10.1053/j.ackd.2020.03.002. Green open access
file

Phillips, I; Shephard, EA; (2020) Flavin-containing monooxygenase 3 (FMO3): genetic variants and their consequences for drug metabolism and disease. Xenobiotica , 50 (1) pp. 19-33. 10.1080/00498254.2019.1643515. Green open access
file

Phillips, IR; Shephard, EA; (2020) Flavin-containing monooxygenases: new structures from old proteins. Nature Structural & Molecular Biology , 27 pp. 3-4. 10.1038/s41594-019-0356-1. Green open access
file

Ramsay, Ewan Phillip; Abascal-Palacios, Guillermo; Daiss, Julia L; King, Helen; Gouge, Jerome; Pilsl, Michael; Beuron, Fabienne; ... Vannini, Alessandro; + view all (2020) Structure of human RNA polymerase III. Nature Communications , 11 (1) , Article 6409. 10.1038/s41467-020-20262-5. Green open access
file

Redlingshöfer, L; McLeod, F; Chen, Y; Camus, MD; Burden, JJ; Palomer, E; Briant, K; ... Brodsky, FM; + view all (2020) Clathrin light chain diversity regulates membrane deformation in vitro and synaptic vesicle formation in vivo. Proceedings of the National Academy of Sciences 10.1073/pnas.2003662117. (In press). Green open access
file

Ridgway, Z; Eldrid, CFS; Zhyvoloup, A; Ben-Younis, A; Noh, D; Thalassinos, K; Raleigh, DP; (2020) Analysis of Proline Substitutions Reveals the Plasticity and Sequence Sensitivity of Human IAPP Amyloidogenicity and Toxicity. Biochemistry , 59 (6) pp. 742-754. 10.1021/acs.biochem.9b01109. Green open access
file

Roddan, R; Sula, A; Méndez-Sánchez, D; Subrizi, F; Lichman, BR; Broomfield, J; Richter, M; ... Hailes, HC; + view all (2020) Single step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases. Communications Chemistry , 3 (1) 10.1038/s42004-020-00416-8. (In press). Green open access
file

Roddan, R; Ward, JM; Keep, NH; Hailes, HC; (2020) Pictet–Spenglerases in alkaloid biosynthesis: Future applications in biocatalysis. Current Opinion in Chemical Biology , 55 pp. 69-76. 10.1016/j.cbpa.2019.12.003. Green open access
file

Runolfsdottir, H; Lin, T-L; Goldfarb, D; Sayer, J; Michael, M; Ketteridge, D; Rich, P; ... Palsson, R; + view all (2020) Are conventional stone analysis techniques reliable for the identification of 2,8-dihydroxyadenine kidney stones? A case series. Urolithiasis , 48 pp. 337-344. 10.1007/s00240-020-01187-6. Green open access
file

Sachdeva, A; Gouge, J; Kontovounisios, C; Nikolaou, S; Ashworth, A; Lim, K; Chong, I; (2020) Klotho and the Treatment of Human Malignancies. Cancers , 12 (6) , Article 1665. 10.3390/cancers12061665. Green open access
file

Sait, LG; Sula, A; Ghovanloo, M-R; Hollingworth, D; Ruben, PC; Wallace, BA; (2020) Cannabidiol interactions with voltage-gated sodium channels. eLife , 9 , Article e58593. 10.7554/eLife.58593. Green open access
file

Santini, JM; Edwards, SJL; (2020) Host range of SARS-CoV-2 and implications for public health. The Lancet Microbe 10.1016/s2666-5247(20)30069-0. (In press). Green open access
file

Scholes, HM; Cryar, A; Kerr, F; Sutherland, D; Gethings, LA; Vissers, JPC; Lees, JG; ... Thalassinos, K; + view all (2020) Dynamic changes in the brain protein interaction network correlates with progression of Aβ42 pathology in Drosophila. Scientific Reports , 10 , Article 18517. 10.1038/s41598-020-74748-9. Green open access
file

Sillitoe, I; Bordin, N; Dawson, N; Waman, VP; Ashford, P; Scholes, HM; Pang, CSM; ... Orengo, CA; + view all (2020) CATH: increased structural coverage of functional space. Nucleic Acids Research 10.1093/nar/gkaa1079. (In press). Green open access
file

Sinnott, M; Malhotra, S; Madhusudhan, MS; Thalassinos, K; Topf, M; (2020) Combining Information from Crosslinks and Monolinks in the Modeling of Protein Structures. Structure , 28 (9) 1061-1070.e3. 10.1016/j.str.2020.05.012. Green open access
file

Song, Y; Dagil, L; Fairall, L; Robertson, N; Wu, M; Ragan, TJ; Savva, CG; ... Schwabe, JWR; + view all (2020) Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex. Cell Reports , 30 (8) 2699-2711.e8. 10.1016/j.celrep.2020.01.091. Green open access
file

Spakman, D; King, GA; Peterman, EJG; Wuite, GJL; (2020) Constructing arrays of nucleosome positioning sequences using Gibson Assembly for single-molecule studies. Scientific Reports , 10 , Article 9903. 10.1038/s41598-020-66259-4. Green open access
file

Stancheva, VG; Li, X-H; Hutchings, J; Gomez-Navarro, N; Santhanam, B; Babu, MM; Zanetti, G; (2020) Combinatorial multivalent interactions drive cooperative assembly of the COPII coat. Journal of Cell Biology , 219 (11) 10.1083/jcb.202007135. Green open access
file

Szkop, KJ; Moss, DS; Nobeli, I; (2020) flexiMAP: a regression-based method for discovering differential alternative polyadenylation events in standard RNA-seq data. Bioinformatics 10.1093/bioinformatics/btaa854. (In press). Green open access
file

Tossounian, M-A; Khanh Truong, A-C; Buts, L; Wahni, K; Mourenza, Á; Leermakers, M; Vertommen, D; ... Messens, J; + view all (2020) Methionine sulfoxide reductase B from Corynebacterium diphtheriae catalyzes sulfoxide reduction via an intramolecular disulfide cascade. Journal of Biological Chemistry 10.1074/jbc.RA119.012438. (In press). Green open access
file

Tossounian, M-A; Zhang, B; Gout, I; (2020) The Writers, Readers, and Erasers in Redox Regulation of GAPDH. Antioxidants , 9 (12) , Article 1288. 10.3390/antiox9121288. Green open access
file

Townsend-Nicholson, A; (2020) Educating and engaging new communities of practice with high performance computing through the integration of teaching and research. Interface Focus , 10 (6) , Article 20200003. 10.1098/rsfs.2020.0003. Green open access
file

Tsuchiya, Y; Byrne, DP; Burgess, SG; Bormann, J; Baković, J; Huang, Y; Zhyvoloup, A; ... Gout, I; + view all (2020) Covalent Aurora A regulation by the metabolic integrator coenzyme A. Redox Biology , 28 , Article 101318. 10.1016/j.redox.2019.101318. Green open access
file

Ubbink, M; Ben Bdira, F; Waudby, CA; Volkov, AN; Schröder, SP; Ab, E; Codée, JDC; ... van Ingen, H; + view all (2020) Dynamics of ligand binding to a rigid glycosidase. Angewandte Chemie International Edition 10.1002/anie.202003236. (In press). Green open access
file

Vedithi, Sundeep Chaitanya; Malhotra, Sony; Skwark, Marcin J; Munir, Asma; Acebron-Garcia-De-Eulate, Marta; Waman, Vaishali P; Alsulami, Ali; ... Blundell, Tom L; + view all (2020) HARP: a database of structural impacts of systematic missense mutations in drug targets of Mycobacterium leprae. Computational and Structural Biotechnology Journal , 18 pp. 3692-3704. 10.1016/j.csbj.2020.11.013. Green open access
file

Veeravalli, S; Phillips, IR; Freire, RT; Varshavi, D; Everett, JR; Shephard, EA; (2020) Flavin-Containing Monooxygenase 1 Catalyzes the Production of Taurine from Hypotaurine. Drug Metabolism and Disposition , 48 (5) pp. 378-385. 10.1124/dmd.119.089995. Green open access
file

Von Loeffelholz, O; Purkiss, A; Cao, L; Kjaer, S; Kogata, N; Romet-Lemonne, G; Way, M; (2020) Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms. Biology Open 10.1242/bio.054304. (In press). Green open access
file

Wan, S; Potterton, A; Husseini, FS; Wright, DW; Heifetz, A; Malawski, M; Townsend-Nicholson, A; (2020) Hit-to-lead and lead optimization binding free energy calculations for G protein-coupled receptors. Interface Focus , 10 (6) , Article 20190128. 10.1098/rsfs.2019.0128. Green open access
file

Wang, H; Dienemann, C; Stuetzer, A; Urlaub, H; Cheung, ACM; Cramer, P; (2020) Structure of the transcription coactivator SAGA. Nature , 577 pp. 717-720. 10.1038/s41586-020-1933-5. Green open access
file

Waudby, CA; Christodoulou, J; (2020) NMR Lineshape Analysis of Intrinsically Disordered Protein Interactions. Intrinsically Disordered Proteins , 2141 pp. 477-504. 10.1007/978-1-0716-0524-0_24. Green open access
file

Waudby, CA; Ouvry, M; Davis, B; Christodoulou, J; (2020) Two-dimensional NMR lineshape analysis of single, multiple, zero and double quantum correlation experiments. Journal of Biomolecular NMR , 74 pp. 95-109. 10.1007/s10858-019-00297-7. Green open access
file

Werbeck, ND; Shukla, VK; Kunze, MBA; Yalinca, H; Pritchard, RB; Siemons, L; Mondal, S; ... Hansen, DF; + view all (2020) A distal regulatory region of a class I human histone deacetylase. Nature Communications , 11 (1) , Article 3841. 10.1038/s41467-020-17610-w. Green open access
file

Wu, F; de Boer, R; Krikken, AM; Aksit, A; Bordin, N; Devos, DP; van der Klei, IJ; (2020) Pex24 and Pex32 are required to tether peroxisomes to the ER for organelle biogenesis, positioning and segregation in yeast. Journal of Cell Science , 133 (16) , Article jcs246983. 10.1242/jcs.246983. Green open access
file

Yardimci, Sevim; Burnham, Daniel R; Terry, Samantha YA; Yardimci, Hasan; (2020) Three-dimensional super-resolution fluorescence imaging of DNA. Scientific Reports , 10 , Article 12504. 10.1038/s41598-020-68892-5. Green open access
file

Zeeshan, M; Brady, D; Stanway, RR; Moores, CA; Holder, AA; Tewari, R; (2020) Plasmodium berghei Kinesin-5 Associates With the Spindle Apparatus During Cell Division and Is Important for Efficient Production of Infectious Sporozoites. Frontiers in Cellular and Infection Microbiology , 10 , Article 583812. 10.3389/fcimb.2020.583812. Green open access
file

Zhyvoloup, A; Yu, BYK; Baković, J; Davis-Lunn, M; Tossounian, M-A; Thomas, N; Tsuchiya, Y; ... Gout, I; + view all (2020) Analysis of disulphide bond linkage between CoA and protein cysteine thiols during sporulation and in spores of Bacillus species. FEMS Microbiology Letters , 367 (27) , Article fnaa174. 10.1093/femsle/fnaa174. Green open access
file

Zink, IA; Fouqueau, T; Tarrason Risa, G; Werner, F; Baum, B; Bläsi, U; Schleper, C; (2020) Comparative CRISPR type III-based knockdown of essential genes in hyperthermophilic Sulfolobales and the evasion of lethal gene silencing. RNA Biology 10.1080/15476286.2020.1813411. (In press). Green open access
file

Working / discussion paper

Lam, SD; Bordin, N; Waman, VP; Scholes, HM; Ashford, P; Sen, N; van Dorp, L; ... Orengo, CA; + view all (2020) SARS-CoV-2 spike protein predicted to form complexes with host receptor protein orthologues from a broad range of mammals. BioRxiv: Cold Spring Harbor, NY, USA. Green open access
file

Thesis

Bultitude, Will P.; (2020) Generating full-length Killer-cell Immunoglobulin-like Receptor (KIR) gene sequences using Third Generation long-amplicon sequencing to assess the impact of KIR polymorphism on Haematopoietic Cell Transplantation outcomes. Doctoral thesis (Ph.D), UCL (University College London). Green open access
file

Kampyli, Charis; (2020) Investigation into the cell biological roles of class II PI3K-C2β. Doctoral thesis (Ph.D), UCL (University College London). Green open access
file

Siemons, Lucas; (2020) Characterising side-chain motions in proteins by Nuclear Magnetic Resonance and Molecular Dynamics to report on function and regulation. Doctoral thesis (Ph.D), UCL (University College London). Green open access
file

This list was generated on Wed May 8 17:10:42 2024 BST.