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Article

Abdolvand, N; Tostoes, R; Raimes, W; Kumar, V; Szita, N; Veraitch, F; (2018) Long‐Term Retinal Differentiation of Human Induced Pluripotent Stem Cells in a Continuously Perfused Microfluidic Culture Device. Biotechnology Journal , Article 1800323. 10.1002/biot.201800323. (In press). Green open access
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Ali, J; Rafiq, QA; Ratcliffe, E; (2018) Antimicrobial resistance mechanisms and potential synthetic treatments. Future Science OA , 4 (4) , Article FSO290. 10.4155/fsoa-2017-0109. Green open access
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Arnott, PM; Joshi, H; Aksimentiev, A; Howorka, S; (2018) Dynamic Interactions between Lipid-Tethered DNA and Phospholipid Membranes. Langmuir , 34 (39) pp. 15084-15092. 10.1021/acs.langmuir.8b02271. Green open access
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Bateson, P; Fleet, JEH; Riseley, AS; Janeva, E; Marcella, AS; Farinea, C; Kuptsova, M; ... Parker, BM; + view all (2018) Electrochemical Characterisation of Bio-Bottle-Voltaic (BBV) Systems Operated with Algae and Built with Recycled Materials. Biology , 7 (2) , Article 26. 10.3390/biology7020026. Green open access
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Bawn, M; Subrizi, F; Lye, GJ; Sheppard, TD; Hailes, HC; Ward, JM; (2018) Data on a thermostable enzymatic one-pot reaction for the production of a high-value compound from L-arabinose. Data in Brief , 19 pp. 1341-1354. 10.1016/j.dib.2018.05.140. Green open access
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Bawn, M; Subrizi, F; Lye, GJ; Sheppard, TD; Hailes, HC; Ward, JM; (2018) One-pot, two-step transaminase and transketolase synthesis of L-gluco-heptulose from L-arabinose. Enzyme and Microbial Technology , 116 pp. 16-22. 10.1016/j.enzmictec.2018.05.006. Green open access
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Bláha, BAF; Morris, SA; Ogonah, OW; Crescente, V; Rosenberg, W; Maucourant, S; Mukhopadhyay, TK; (2018) Development of a high-throughput microscale cell disruption platform for Pichia pastoris in rapid bioprocess design. Biotechnology Progress , 34 (1) pp. 130-140. 10.1002/btpr.2555. Green open access
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Blas, P; Tolner, B; Ward, J; Chester, K; Hoare, M; (2018) The use of a surface active agent in the protection of a fusion protein during bioprocessing. Biotechnology and Bioengineering , 115 (11) pp. 2760-2770. 10.1002/bit.26817. Green open access
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Boeing, P; Leon, M; Nesbeth, DN; Finkelstein, A; Barnes, C; (2018) Towards an Aspect-Oriented Design and Modelling Framework for Synthetic Biology. Processes , 6 (9) , Article 167. 10.3390/pr6090167. Green open access
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Cárdenas-Fernández, M; Hamley-Bennett, C; Leak, DJ; Lye, GJ; (2018) Continuous enzymatic hydrolysis of sugar beet pectin and l-arabinose recovery within an integrated biorefinery. Bioresour Technol , 269 pp. 195-202. 10.1016/j.biortech.2018.08.069. Green open access
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Chilima, TDP; Moncaubeig, F; Farid, SS; (2018) Impact of allogeneic stem cell manufacturing decisions on cost of goods, process robustness and reimbursement. Biochemical Engineering Journal , 137 pp. 132-151. 10.1016/j.bej.2018.04.017. Green open access
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Colao, IL; Corteling, R; Bracewell, D; Wall, I; (2018) Manufacturing Exosomes: A Promising Therapeutic Platform. Trends in Molecular Medicine , 24 (3) pp. 242-256. 10.1016/j.molmed.2018.01.006. Green open access
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Cossu, G; Birchall, M; Brown, T; De Coppi, P; Culme-Seymour, E; Gibbon, S; Hitchcock, J; ... Wilson, JGS; + view all (2018) Lancet Commission: Stem Cells and Regenerative Medicine. The Lancet , 391 (10123) pp. 883-910. 10.1016/S0140-6736(17)31366-1. Green open access
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Cuff, S; Lewis, RD; Chinje, E; Jaffar, M; Knox, R; Weeks, I; (2018) An improved cell-permeable fluorogenic substrate as the basis for a highly sensitive test for NAD(P)H quinone oxidoreductase 1 (NQO1) in living cells. Free Radical Biology and Medicine , 116 pp. 141-148. 10.1016/j.freeradbiomed.2018.01.009. Green open access
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de lamotte, A; Delafosse, A; Calvo, S; Toye, D; (2018) Analysis of PIV measurements using modal decomposition techniques, POD and DMD, to study flow structures and their dynamics within a stirred-tank reactor. Chemical Engineering Science , 178 pp. 348-366. 10.1016/j.ces.2017.12.047. Green open access
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de Lamotte, A; Delafosse, A; Calvo, S; Toye, D; (2018) Identifying dominant spatial and time characteristics of flow dynamics within free-surface baffled stirred-tanks from CFD simulations. Chemical Engineering Science , 192 pp. 128-142. 10.1016/j.ces.2018.07.024. Green open access
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Detela, G; Bain, OW; Kim, H-W; Williams, DJ; Mason, C; Mathur, A; Wall, IB; (2018) Donor Variability in Growth Kinetics of Healthy hMSCs Using Manual Processing: Considerations for Manufacture of Cell Therapies. Biotechnology Journal , 13 (2) , Article 1700085. 10.1002/biot.201700085. Green open access
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Dimov, N; Kastner, E; Hussain, M; Perrie, Y; Szita, N; (2018) Author Correction: Formation and purification of tailored liposomes for drug delivery using a module-based micro continuous-flow system. Scientific Reports , 8 (1) , Article 6762. 10.1038/s41598-018-25217-x. Green open access
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Efthymiou, M; Arachchillage, DRJ; Lane, PJ; O'Keeffe, AG; McDonnell, T; Cohen, H; Mackie, IJ; (2018) Antibodies against TFPI and protein C are associated with a severe thrombotic phenotype in patients with and without antiphospholipid syndrome. Thrombosis Research , 170 pp. 60-68. 10.1016/j.thromres.2018.08.003. Green open access
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El-Sabbahy, H; Ward, D; Ogonah, O; Deakin, L; Jellum, GM; Bracewell, DG; (2018) The effect of feed quality due to clarification strategy on the design and performance of protein A periodic counter-current chromatography. Biotechnology Progress , 34 (6) pp. 1380-1392. 10.1002/btpr.2709. Green open access
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Farid, S; (2018) Technologies for large-scale umbilical cord-derived MSC expansion: Experimental performance and cost of goods analysis. Biochemical Engineering Journal , 135 pp. 36-48. 10.1016/j.bej.2018.02.018. Green open access
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Fazilah, Nurul Farhana; Ariff, Arbakariya B; Khayat, Mohd Ezuan; Rios-Solis, Leonardo; Halim, Murni; (2018) Influence of probiotics, prebiotics, synbiotics and bioactive phytochemicals on the formulation of functional yogurt. Journal of Functional Foods , 48 pp. 387-399. 10.1016/j.jff.2018.07.039. Green open access
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Forbes, N; Hussain, MT; Briuglia, ML; Edwards, DP; Horst, JHT; Szita, N; Perrie, Y; (2018) Rapid and scale-independent microfluidic manufacture of liposomes entrapping protein incorporating in-line purification and at-line size monitoring. International Journal of Pharmaceutics , 556 pp. 68-81. 10.1016/j.ijpharm.2018.11.060. Green open access
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Forte, N; Livanos, M; Miranda, E; Morais, M; Yang, X; Rajkumar, VS; Chester, KA; ... Baker, JR; + view all (2018) Tuning the Hydrolytic Stability of Next Generation Maleimide Cross-Linkers Enables Access to Albumin-Antibody Fragment Conjugates and tri-scFvs. Bioconjugate Chemistry , 29 (2) pp. 486-492. 10.1021/acs.bioconjchem.7b00795. Green open access
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Fuldauer, L; Parker, B; Yaman, R; Borrion, A; (2018) Managing anaerobic digestate from food waste in the urban environment: Evaluating the feasibility from an interdisciplinary perspective. Journal of Cleaner Production , 185 pp. 929-940. 10.1016/j.jclepro.2018.03.045. Green open access
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Georgiou, M; Reis, JND; Wood, R; Esteban, PP; Roberton, V; Mason, C; Li, D; ... Wall, I; + view all (2018) Bioprocessing strategies to enhance the challenging isolation of neuro-regenerative cells from olfactory mucosa. Scientific Reports , 8 , Article 14440. 10.1038/s41598-018-32748-w. Green open access
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Goldrick, S; Lee, K; Spencer, C; Holmes, W; Kuiper, M; Turner, R; Farid, SS; (2018) On-line control of glucose concentration in high-yielding mammalian cell cultures enabled through oxygen transfer rate measurements. Biotechnology Journal , 13 (4) , Article 1700607. 10.1002/biot.201700607. Green open access
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Goldrick, S; Lovett, D; Montague, G; Lennox, B; (2018) Influence of Incident Wavelength and Detector Material Selection on Fluorescence in the Application of Raman Spectroscopy to a Fungal Fermentation Process. Bioengineering , 5 (4) , Article 79. 10.3390/bioengineering5040079. Green open access
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Gruber, P; Carvalho, F; Marques, MPC; O'Sullivan, B; Subrizi, F; Dobrijevic, D; Ward, J; ... Szita, N; + view all (2018) Enzymatic synthesis of chiral amino-alcohols by coupling transketolase and transaminase-catalyzed reactions in a cascading continuous-flow microreactor system. Biotechnology and Bioengineering , 115 pp. 586-596. 10.1002/bit.26470. Green open access
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Harrison, RP; Medcalf, N; Rafiq, QA; (2018) Cell therapy-processing economics: Small-scale microfactories as a stepping stone toward large-scale macrofactories. Regenerative Medicine , 13 (2) pp. 159-173. 10.2217/rme-2017-0103. Green open access
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Harrison, RP; Rafiq, QA; Medcalf, N; (2018) Centralised versus decentralised manufacturing and the delivery of healthcare products: A United Kingdom exemplar. Cytotherapy , 20 (6) pp. 873-890. 10.1016/j.jcyt.2018.05.003. Green open access
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Harrison, RP; Ruck, S; Rafiq, QA; Medcalf, N; (2018) Decentralised manufacturing of cell and gene therapy products: Learning from other healthcare sectors. Biotechnology Advances , 36 (2) pp. 345-357. 10.1016/j.biotechadv.2017.12.013. Green open access
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Hauck, NC; Kirpach, J; Kiefer, C; Farinelle, S; Maucourant, S; Morris, SA; Rosenberg, W; ... Lu, I-N; + view all (2018) Applying Unique Molecular Identifiers in Next Generation Sequencing Reveals a Constrained Viral Quasispecies Evolution under Cross-Reactive Antibody Pressure Targeting Long Alpha Helix of Hemagglutinin. Viruses , 10 (4) , Article 148. 10.3390/v10040148. Green open access
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Heathman, TRJ; Nienow, AW; Rafiq, QA; Coopman, K; Kara, B; Hewitt, CJ; (2018) Agitation and aeration of stirred-bioreactors for the microcarrier culture of human mesenchymal stem cells and potential implications for large-scale bioprocess development. Biochemical Engineering Journal , 136 pp. 9-17. 10.1016/j.bej.2018.04.011. Green open access
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Hirschmann, R; Borodkin, N; Baganz, F; Hass, VC; (2018) Towards the integration of the anaerobic ethyl (S)-3-hydroxybutyrate production process into a biorefinery concept. Chemical Engineering Transactions , 70 pp. 559-564. 10.3303/CET1870094. Green open access
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Isimite, J; Baganz, F; Hass, VC; (2018) Operator training simulators for biorefineries: current position and future directions. Journal of Chemical Technology and Biotechnology , 93 (6) pp. 1529-1541. 10.1002/jctb.5583. Green open access
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Jenkins, MJ; Farid, SS; (2018) Cost-effective bioprocess design for the manufacture of allogeneic CAR-T cell therapies using a decisional tool with multi-attribute decision-making analysis. Biochemical Engineering Journal , 137 pp. 192-204. 10.1016/j.bej.2018.05.014. Green open access
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Johnson, TF; Bailey, JJ; Iacoviello, F; Welsh, JH; Levison, PR; Shearing, PR; Bracewell, DG; (2018) Three dimensional characterisation of chromatography bead internal structure using X-ray computed tomography and focused ion beam microscopy. Journal of Chromatography A , 1566 pp. 79-88. 10.1016/j.chroma.2018.06.054. Green open access
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Kilic, T; Valinhas, ATDS; Wall, I; Renaud, P; Carrara, S; (2018) Label-free detection of hypoxia-induced extracellular vesicle secretion from MCF-7 cells. Scientific Reports , 8 , Article 9402. 10.1038/s41598-018-27203-9. Green open access
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Konstantinidis, S; Welsh, JP; Titchener-Hooker, NJ; Roush, DJ; Velayudhan, A; (2018) Data‐driven multi‐objective optimization via grid compatible simplex technique and desirability approach for challenging high throughput chromatography applications. Biotechnology Progress , 34 (6) 10.1002/btpr.2673. Green open access
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Kühlbach, C; da Luz, S; Baganz, F; Hass, VC; Mueller, MM; (2018) A microfluidic system for the investigation of tumor cell extravasation. Bioengineering , 5 (2) , Article 40. 10.3390/bioengineering5020040. Green open access
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Lee, MJ; Mantell, J; Brown, IR; Fletcher, JM; Verkade, P; Pickersgill, RW; Woolfson, DN; ... Warren, MJ; + view all (2018) De novo targeting to the cytoplasmic and luminal side of bacterial microcompartments. Nature Communications , 9 , Article 3413. 10.1038/s41467-018-05922-x. Green open access
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Lee, MJ; Mantell, J; Hodgson, L; Alibhai, D; Fletcher, JM; Brown, IR; Frank, S; ... Warren, MJ; + view all (2018) Engineered synthetic scaffolds for organizing proteins within the bacterial cytoplasm. Nature Chemical Biology , 14 (2) pp. 142-147. 10.1038/nchembio.2535. Green open access
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Leipold, L; Dobrijevic, D; Jeffries, J; Bawn, M; Moody, T; Ward, J; Hailes, HC; (2018) The identification and use of robust transaminases from a domestic drain metagenome. RSC Green Chemistry , 1 pp. 75-86. 10.1039/c8gc02986e. Green open access
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McDonnell, T; Artim-Esen, B; Wincup, C; Ripoll, VM; Isenberg, D; Giles, IP; Rahman, A; (2018) Antiphospholipid Antibodies to Domain I of Beta-2-Glycoprotein I Show Different Subclass Predominance in Comparison to Antibodies to Whole Beta-2-glycoprotein I. Frontiers in Immunology , 9 (2224) 10.3389/fimmu.2018.02244. Green open access
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McDonnell, TCR; Willis, R; Pericleous, C; Ripoll, VM; Giles, IP; Isenberg, DA; Brasier, AR; ... Rahman, A; + view all (2018) PEGylated Domain I of Beta-2-Glycoprotein I Inhibits the Binding, Coagulopathic, and Thrombogenic Properties of IgG From Patients With the Antiphospholipid Syndrome. Frontiers in Immunology , 9 , Article 2413. 10.3389/fimmu.2018.02413. Green open access
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McDonnell, TCR; Wincup, C; Rahman, A; Giles, I; (2018) Going viral in rheumatology: Using social media to show that mechanistic research is relevant to patients with lupus and antiphospholipid syndrome. Rheumatology Advances in Practice , 2 (1) , Article rky003. 10.1093/rap/rky003. Green open access
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Melinek, BJ; Dessoy, S; Wright, B; Bracewell, DG; Mukhopadhyay, TK; (2018) Ultra scale-down approaches to study the centrifugal harvest for viral vaccine production. Biotechnology and Bioengineering , 115 (5) pp. 1226-1238. 10.1002/bit.26546. Green open access
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Micheletti, M; Rodriguez, G; Ducci, A; (2018) Macro- and micro-scale mixing in a shaken bioreactor for fluids of high viscosity. Chemical Engineering Research and Design , 132 pp. 890-901. 10.1016/j.cherd.2018.01.018. Green open access
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Mitchell, SA; Truscott, F; Dickman, R; Ward, J; Tabor, AB; (2018) Simplified lipid II-binding antimicrobial peptides: Design, synthesis and antimicrobial activity of bioconjugates of nisin rings A and B with pore-forming peptides. Bioorganic & Medicinal Chemistry , 26 (21) pp. 5691-5700. 10.1016/j.bmc.2018.10.015. Green open access
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Mukhopadhyay, A; Basu, S; Sinha, S; Patra, H; (2018) Inner-View of Nanomaterial Incited Protein Conformational Changes: Insights into Designable Interaction. [Review]. Research , 2018 , Article 9712832. 10.1155/2018/9712832. Green open access
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Nweke, MC; Rathore, AS; Bracewell, DG; (2018) Lifetime and Aging of Chromatography Resins during Biopharmaceutical Manufacture. [Editorial comment]. Trends in Biotechnology , 36 (10) pp. 992-995. 10.1016/j.tibtech.2018.01.001. Green open access
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Oshinbolu, S; Shah, R; Finka, G; Molloy, M; Uden, M; Bracewell, DG; (2018) Evaluation of fluorescent dyes to measure protein aggregation within mammalian cell culture supernatants. Journal of Chemical Technology and Biotechnology , 93 (3) pp. 909-917. 10.1002/jctb.5519. Green open access
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Oshinbolu, S; Wilson, LJ; Lewis, W; Shah, R; Bracewell, DG; (2018) Measurement of impurities to support process development and manufacture of biopharmaceuticals. TrAC Trends in Analytical Chemistry , 101 pp. 120-128. 10.1016/j.trac.2017.10.026. Green open access
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Othman, M; Ariff, AB; Kapri, MR; Rios-Solis, L; Halim, M; (2018) Growth Enhancement of Probiotic Pediococcus acidilactici by Extractive Fermentation of Lactic Acid Exploiting Anion-Exchange Resin. Frontiers in Microbiology , 9 , Article 2554. 10.3389/fmicb.2018.02554. Green open access
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Pallipurath Radhakrishnan, AN; Marques, MPC; Davies, MJ; O'Sullivan, B; Bracewell, DG; Szita, N; (2018) Flocculation on a chip: a novel screening approach to determine floc growth rates and select flocculating agents. Lab on a Chip 10.1039/C7LC00793K. (In press). Green open access
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Pandya, A; Howard, MJ; Zloh, M; Dalby, PA; (2018) An Evaluation of the Potential of NMR Spectroscopy and Computational Modelling Methods to Inform Biopharmaceutical Formulations. Pharmaceutics , 10 (4) , Article 165. 10.3390/pharmaceutics10040165. Green open access
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Patel, N; Bracewell, DG; Sorensen, E; (2018) Dynamic modelling of aqueous two-phase systems to quantify the impact of bioprocess design, operation and variability. Food and Bioproducts Processing , 107 pp. 10-24. 10.1016/j.fbp.2017.10.005. Green open access
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Pathak, M; Rathore, AS; Lintern, K; Bracewell, DG; (2018) Protein A chromatography resin lifetime—impact of feed composition. Biotechnology Progress , 34 (2) pp. 412-419. 10.1002/btpr.2608. Green open access
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Rafiq, QA; Ruck, S; Hanga, MP; Heathman, TRJ; Coopman, K; Nienow, AW; Williams, DJ; (2018) Qualitative and quantitative demonstration of bead-to-bead transfer with bone marrow-derived human mesenchymal stem cells on microcarriers: Utilising the phenomenon to improve culture performance. Biochemical Engineering Journal , 135 pp. 11-21. 10.1016/j.bej.2017.11.005. Green open access
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Ramirez, A; Morris, S; Maucourant, S; D'Ascanio, I; Crescente, V; Lu, I-N; Farinelle, S; ... Rosenberg, W; + view all (2018) A virus-like particle vaccine candidate for influenza A virus based on multiple conserved antigens presented on hepatitis B tandem core particles. Vaccine , 36 (6) pp. 873-880. 10.1016/j.vaccine.2017.12.053. Green open access
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Ridley, CJA; Parker, BM; Norman, L; Schlarb-Ridley, B; Dennis, R; Jamieson, AE; Clark, D; ... Davey, MP; + view all (2018) Growth of microalgae using nitrate-rich brine wash from the water industry. Algal Research , 33 pp. 91-98. 10.1016/j.algal.2018.04.018. Green open access
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Ripoll, VM; Pregnolato, F; Mazza, S; Bodio, C; Grossi, C; McDonnell, T; Pericleous, C; ... Giles, IP; + view all (2018) Gene expression profiling identifies distinct molecular signatures in thrombotic and obstetric antiphospholipid syndrome. Journal of Autoimmunity 10.1016/j.jaut.2018.07.002. (In press). Green open access
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Salih, O; He, S; Planamente, S; Stach, L; MacDonald, JT; Manoli, E; Scheres, SHW; ... Freemont, PS; + view all (2018) Atomic Structure of Type VI Contractile Sheath from Pseudomonas aeruginosa. Structure , 26 (2) pp. 329-336. 10.1016/j.str.2017.12.005. Green open access
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Samaras, JJ; Abecasis, B; Serra, M; Ducci, A; Micheletti, M; (2018) Impact of hydrodynamics on iPSC-derived cardiomyocyte differentiation processes. Journal of Biotechnology , 287 pp. 18-27. 10.1016/j.jbiotec.2018.07.028. Green open access
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Smith, DM; Culme-Seymour, EJ; Mason, C; (2018) Evolving Industry Partnerships and Investments in Cell and Gene Therapies. Cell Stem Cell , 22 (5) pp. 623-626. 10.1016/j.stem.2018.03.004. Green open access
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Smith, F; Velayudhan, A; Voulgarelis, D; (2018) Stochastic analysis of a full system of two competing populations in a chemostat. Chemical Engineering Science , 175 pp. 424-444. 10.1016/j.ces.2017.10.052. Green open access
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Strnisa, F; Bajic, M; Panjan, P; Plazl, I; Sesay, AM; Znidarsic-Plazl, P; (2018) Characterization of an enzymatic packed-bed microreactor: Experiments and modeling. Chemical Engineering Journal , 350 pp. 541-550. 10.1016/j.cej.2018.05.028. Green open access
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Torres-Acosta, MA; Pereira, JFB; Freire, MG; Aguilar-Yanez, JM; Coutinho, JAP; Titchener-Hooker, NJ; Rito-Palomares, M; (2018) Economic evaluation of the primary recovery of tetracycline with traditional and novel aqueous two-phase systems. Separation and Purification Technology , 203 pp. 178-184. 10.1016/j.seppur.2018.04.041. Green open access
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Tsuchiya, Y; Zhyvoloup, A; Bakovic, J; Thomas, N; Yi Kun Yu, B; Das, S; Orengo, C; ... Gout, I; + view all (2018) Protein CoAlation and antioxidant function of Coenzyme A in prokaryotic cells. Biochemical Journal , 475 (11) pp. 1909-1937. 10.1042/BCJ20180043. Green open access
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Uddin, I; Frank, S; Warren, MJ; Pickersgill, RW; (2018) A Generic Self-Assembly Process in Microcompartments and Synthetic Protein Nanotubes. Small , 14 (19) , Article 1704020. 10.1002/smll.201704020. Green open access
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Vazquez-Villegas, P; Espitia-Saloma, E; Torres-Acosta, MA; Ruiz-Ruiz, F; Rito-Palomares, M; Aguilar, O; (2018) Factorial and Economic Evaluation of an Aqueous Two-Phase Partitioning Pilot Plant for Invertase Recovery From Spent Brewery Yeast. Frontiers in Chemistry , 6 , Article 454. 10.3389/fchem.2018.00454. Green open access
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Velez-Suberbie, ML; Betts, JPJ; Walker, KL; Robinson, C; Zoro, B; Keshavarz-Moore, E; (2018) High throughput automated microbial bioreactor system used for clone selection and rapid scale-down process optimization. Biotechnology Progress , 34 (1) pp. 58-68. 10.1002/btpr.2534. Green open access
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Villegas-Torres, MF; Ward, JM; Baganz, F; (2018) Optimisation of enzyme cascades for chiral amino alcohol synthesis in aid of host cell integration using a statistical experimental design approach. Journal of Biotechnology , 281 pp. 150-160. 10.1016/j.jbiotec.2018.07.014. Green open access
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Vormittag, P; Gunn, R; Ghorashian, S; Veraitch, FS; (2018) A guide to manufacturing CAR T cell therapies. Current Opinion in Biotechnology , 53 pp. 164-181. 10.1016/j.copbio.2018.01.025. Green open access
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Wayne, CJ; Velayudhan, A; (2018) Modulator Dynamics Shape the Design Space for Stepwise-Elution Simulated Moving Bed Chromatographic Separations. Biotechnology Journal , 13 (8) , Article 1700664. 10.1002/biot.201700664. Green open access
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Weheliye, HW; Cagney, N; Rodriguez, G; Micheletti, M; Ducci, A; (2018) Mode decomposition and Lagrangian structures of the flow dynamics in orbitally shaken bioreactors. Physics of Fluids , 30 , Article 033603. 10.1063/1.5016305. Green open access
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Wei, Y-C; Braun-Galleani, S; Henriquez, M-J; Bandara, S; Nesbeth, DN; (2018) Biotransformation of β-Hydroxypyruvate and Glycolaldehyde to L-Erythrulose by Pichia pastoris strain GS115 overexpressing native Transketolase. Biotechnology Progress , 34 (1) pp. 99-106. 10.1002/btpr.2577. Green open access
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Wiegmann, V; Martinez, CB; Baganz, F; (2018) A simple method to determine evaporation and compensate for liquid losses in small-scale cell culture systems. Biotechnology Letters , 40 (7) pp. 1029-1036. 10.1007/s10529-018-2556-x. Green open access
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Wong, Jeff; de Rond, Tristan; d'Espaux, Leo; van der Horst, Cas; Dev, Ishaan; Rios-Solis, Leo; Kirby, James; ... Keasling, Jay; + view all (2018) High-titer production of lathyrane diterpenoids from sugar by engineered Saccharomyces cerevisiae. Metabolic Engineering , 45 pp. 142-148. 10.1016/j.ymben.2017.12.007. Green open access
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Worsham, RD; Thomas, V; Farid, SS; (2018) Potential of Continuous Manufacturing for Liposomal Drug Products. Biotechnology Journal , Article e1700740. 10.1002/biot.201700740. Green open access
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Yu, H; Dalby, P; (2018) Exploiting correlated molecular-dynamics networks to counteract enzyme activity–stability trade-off. Proceedings of the National Academy of Sciences of the United States of America , 115 (52) E12192-E12200. 10.1073/pnas.1812204115. Green open access
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Yu, H; Dalby, PA; (2018) Coupled molecular dynamics mediate long- and short-range epistasis between mutations that affect stability and aggregation kinetics. Proceedings of the National Academy of Sciences of the United States of America , 115 (47) E11043-E11052. 10.1073/pnas.1810324115. Green open access
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Zhang, C; Samad, M; Yu, H; Chakroun, N; Hilton, D; Dalby, PA; (2018) Computational Design To Reduce Conformational Flexibility and Aggregation Rates of an Antibody Fab Fragment. Molecular Pharmaceutics , 15 (8) pp. 3079-3092. 10.1021/acs.molpharmaceut.8b00186. Green open access
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Zhang, H; Deng, M; Lin, P; Liu, J; Liu, C; Strohl, WR; Wang, S; (2018) Frontiers and Opportunities: Highlights of the 2nd Annual Conference of the Chinese Antibody Society. Antibody Therapeutics , 1 (2) pp. 65-74. 10.1093/abt/tby009. Green open access
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Zhao, J; Lichman, BR; Ward, JM; Hailes, HC; (2018) One-pot chemoenzymatic synthesis of trolline and tetrahydroisoquinoline analogues. Chemical Communications , 54 (11) pp. 1323-1326. 10.1039/c7cc08024g. Green open access
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Book chapter

Farid, SS; Jenkins, MJ; (2018) Bioprocesses for Cell Therapies. In: Jagschies, G and Lindskog, E and Galliher, P, (eds.) Biopharmaceutical Processing: Development, Design, and Implementation of Manufacturing Processes. (pp. 899-930). Elsevier: Amsterdam, Netherlands.

Conference item

McDonnell, T; Bradford, C; Raj, D; Ciurtin, C; Jury, E; Manson, J; (2018) Differential activation of complement in rheumatoid arthritis. Presented at: Annual European Congress of Rheumatology - European League Against Rheumatism (EULAR) - 2018, Amsterdam, Netherlands. Green open access
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Thesis

Ahmad, Asma; (2018) Design and Characterisation of a Scale-Down Platform for the Recovery of Periplasmic Fab’ From E.coli. Doctoral thesis (Eng.D), UCL (University College London). Green open access
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Alkassem, Hasan; (2018) Imaging Antimicrobial Peptides in Action by Atomic Force Microscopy. Doctoral thesis (Eng.D), UCL (University College London). Green open access
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Bláha, Benjamin A. F.; (2018) Platform processes for vaccine production: Development of a universal influenza vaccine using Pichia pastoris. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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De Villiers, Ann-Marie; (2018) High cell density purification strategies for application to antibody and virus-vectored biopharmaceutical products. Doctoral thesis (Ph.D), UCL (University College London).

Field, Nicholas John; (2018) Investigation of multicomponent adsorption isotherms in chromatography using high-throughput formats. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Henriquez Morales, Maria-Jose; (2018) Synthetic Biology Routes To Production Of Chiral Amino-alcohols In Pichia Pastoris. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Jackson, David Shaun Frederick; (2018) Building a Synthetic Pathway For Nylon precursor Biosynthesis. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Jenkins, Michael Joseph; (2018) Decisional tools for cost-effective bioprocess design for cell therapies and patient-specific drug discovery tools. Doctoral thesis (Eng.D), UCL (University College London). Green open access
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Jurlewicz, Kosma Michal; (2018) Use of high-throughput tools to optimise polishing-chromatography sequences for complex feed mixtures. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Khalife, Rana; (2018) The Effect of the nutritional microenvironment on stem cell differentiation. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Khan, Haroon Dawood Sadullah; (2018) Towards development of a platform process for novel Lantiobic production. Doctoral thesis (Eng.D), UCL (University College London). Green open access
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Khan, Muazzam Ali; (2018) Increasing the efficiency of antibody purification process by high throughput technology and intelligent design of experiment. Doctoral thesis (Eng.D), UCL (University College London). Green open access
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Melinek, Beatrice; (2018) Scale Down Mimics for Viral Vaccine Harvest and Early Purification. Doctoral thesis (Eng.D), UCL (University College London). Green open access
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Newton, Joesph Matthew; (2018) Understanding cell lysis in fermentation and its impact on primary recovery using viscosity monitoring. Doctoral thesis (Eng.D), UCL (University College London). Green open access
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Nweke, MC; (2018) Chromatography resin characterisation to analyse lifetime and performance during biopharmaceutical manufacture. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Patel, Nehal; (2018) Development of aqueous two-phase separations by combining high-throughput screening and process modelling. Doctoral thesis (Eng.D), UCL (University College London). Green open access
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Sibley, Michael; (2018) A Cell Engineering Approach to Enzyme-Based Fed-Batch Fermentation. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Tang, Zuming; (2018) Size and Location Controlled Microwell Screening Technologies for Stem Cell Differentiation. Doctoral thesis (Ph.D), UCL (University College London).

Ward, David; (2018) Scalable separation methods for the isolation of monosaccharides in a biorefinery context. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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This list was generated on Mon Oct 28 00:08:08 2024 GMT.