Browse by UCL Departments and Centres
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Number of items: 107.
A
Abdolvand, N;
Tostoes, R;
Raimes, W;
Kumar, V;
Szita, N;
Veraitch, F;
(2018)
Long‐Term Retinal Differentiation of Human Induced Pluripotent Stem Cells in a Continuously Perfused Microfluidic Culture Device.
Biotechnology Journal
, Article 1800323. 10.1002/biot.201800323.
(In press).
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Ahmad, Asma;
(2018)
Design and Characterisation of a Scale-Down Platform for the Recovery of Periplasmic Fab’ From E.coli.
Doctoral thesis (Eng.D), UCL (University College London).
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Ali, J;
Rafiq, QA;
Ratcliffe, E;
(2018)
Antimicrobial resistance mechanisms and potential synthetic treatments.
Future Science OA
, 4
(4)
, Article FSO290. 10.4155/fsoa-2017-0109.
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Alkassem, Hasan;
(2018)
Imaging Antimicrobial Peptides in Action by Atomic Force Microscopy.
Doctoral thesis (Eng.D), UCL (University College London).
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Arnott, PM;
Joshi, H;
Aksimentiev, A;
Howorka, S;
(2018)
Dynamic Interactions between Lipid-Tethered DNA and Phospholipid Membranes.
Langmuir
, 34
(39)
pp. 15084-15092.
10.1021/acs.langmuir.8b02271.
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B
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Bateson, P;
Fleet, JEH;
Riseley, AS;
Janeva, E;
Marcella, AS;
Farinea, C;
Kuptsova, M;
... Parker, BM; + view all
(2018)
Electrochemical Characterisation of Bio-Bottle-Voltaic (BBV) Systems Operated with Algae and Built with Recycled Materials.
Biology
, 7
(2)
, Article 26. 10.3390/biology7020026.
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Bawn, M;
Subrizi, F;
Lye, GJ;
Sheppard, TD;
Hailes, HC;
Ward, JM;
(2018)
Data on a thermostable enzymatic one-pot reaction for the production of a high-value compound from L-arabinose.
Data in Brief
, 19
pp. 1341-1354.
10.1016/j.dib.2018.05.140.
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Bawn, M;
Subrizi, F;
Lye, GJ;
Sheppard, TD;
Hailes, HC;
Ward, JM;
(2018)
One-pot, two-step transaminase and transketolase synthesis of L-gluco-heptulose from L-arabinose.
Enzyme and Microbial Technology
, 116
pp. 16-22.
10.1016/j.enzmictec.2018.05.006.
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Bláha, BAF;
Morris, SA;
Ogonah, OW;
Crescente, V;
Rosenberg, W;
Maucourant, S;
Mukhopadhyay, TK;
(2018)
Development of a high-throughput microscale cell disruption platform for Pichia pastoris in rapid bioprocess design.
Biotechnology Progress
, 34
(1)
pp. 130-140.
10.1002/btpr.2555.
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Bláha, Benjamin A. F.;
(2018)
Platform processes for vaccine production: Development of a universal influenza vaccine using Pichia pastoris.
Doctoral thesis (Ph.D), UCL (University College London).
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Blas, P;
Tolner, B;
Ward, J;
Chester, K;
Hoare, M;
(2018)
The use of a surface active agent in the protection of a fusion protein during bioprocessing.
Biotechnology and Bioengineering
, 115
(11)
pp. 2760-2770.
10.1002/bit.26817.
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Boeing, P;
Leon, M;
Nesbeth, DN;
Finkelstein, A;
Barnes, C;
(2018)
Towards an Aspect-Oriented Design and Modelling Framework for Synthetic Biology.
Processes
, 6
(9)
, Article 167. 10.3390/pr6090167.
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C
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Cárdenas-Fernández, M;
Hamley-Bennett, C;
Leak, DJ;
Lye, GJ;
(2018)
Continuous enzymatic hydrolysis of sugar beet pectin and l-arabinose recovery within an integrated biorefinery.
Bioresour Technol
, 269
pp. 195-202.
10.1016/j.biortech.2018.08.069.
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Chilima, TDP;
Moncaubeig, F;
Farid, SS;
(2018)
Impact of allogeneic stem cell manufacturing decisions on cost of goods, process robustness and reimbursement.
Biochemical Engineering Journal
, 137
pp. 132-151.
10.1016/j.bej.2018.04.017.
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Colao, IL;
Corteling, R;
Bracewell, D;
Wall, I;
(2018)
Manufacturing Exosomes: A Promising Therapeutic Platform.
Trends in Molecular Medicine
, 24
(3)
pp. 242-256.
10.1016/j.molmed.2018.01.006.
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Cossu, G;
Birchall, M;
Brown, T;
De Coppi, P;
Culme-Seymour, E;
Gibbon, S;
Hitchcock, J;
... Wilson, JGS; + view all
(2018)
Lancet Commission: Stem Cells and Regenerative Medicine.
The Lancet
, 391
(10123)
pp. 883-910.
10.1016/S0140-6736(17)31366-1.
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Cuff, S;
Lewis, RD;
Chinje, E;
Jaffar, M;
Knox, R;
Weeks, I;
(2018)
An improved cell-permeable fluorogenic substrate as the basis for a highly sensitive test for NAD(P)H quinone oxidoreductase 1 (NQO1) in living cells.
Free Radical Biology and Medicine
, 116
pp. 141-148.
10.1016/j.freeradbiomed.2018.01.009.
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D
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de lamotte, A;
Delafosse, A;
Calvo, S;
Toye, D;
(2018)
Analysis of PIV measurements using modal decomposition techniques, POD and DMD, to study flow structures and their dynamics within a stirred-tank reactor.
Chemical Engineering Science
, 178
pp. 348-366.
10.1016/j.ces.2017.12.047.
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de Lamotte, A;
Delafosse, A;
Calvo, S;
Toye, D;
(2018)
Identifying dominant spatial and time characteristics of flow dynamics within free-surface baffled stirred-tanks from CFD simulations.
Chemical Engineering Science
, 192
pp. 128-142.
10.1016/j.ces.2018.07.024.
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De Villiers, Ann-Marie;
(2018)
High cell density purification strategies for application to antibody and virus-vectored biopharmaceutical products.
Doctoral thesis (Ph.D), UCL (University College London).
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Detela, G;
Bain, OW;
Kim, H-W;
Williams, DJ;
Mason, C;
Mathur, A;
Wall, IB;
(2018)
Donor Variability in Growth Kinetics of Healthy hMSCs Using Manual Processing: Considerations for Manufacture of Cell Therapies.
Biotechnology Journal
, 13
(2)
, Article 1700085. 10.1002/biot.201700085.
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Dimov, N;
Kastner, E;
Hussain, M;
Perrie, Y;
Szita, N;
(2018)
Author Correction: Formation and purification of tailored liposomes for drug delivery using a module-based micro continuous-flow system.
Scientific Reports
, 8
(1)
, Article 6762. 10.1038/s41598-018-25217-x.
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E
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Efthymiou, M;
Arachchillage, DRJ;
Lane, PJ;
O'Keeffe, AG;
McDonnell, T;
Cohen, H;
Mackie, IJ;
(2018)
Antibodies against TFPI and protein C are associated with a severe thrombotic phenotype in patients with and without antiphospholipid syndrome.
Thrombosis Research
, 170
pp. 60-68.
10.1016/j.thromres.2018.08.003.
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El-Sabbahy, H;
Ward, D;
Ogonah, O;
Deakin, L;
Jellum, GM;
Bracewell, DG;
(2018)
The effect of feed quality due to clarification strategy on the design and performance of protein A periodic counter-current chromatography.
Biotechnology Progress
, 34
(6)
pp. 1380-1392.
10.1002/btpr.2709.
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F
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Farid, S;
(2018)
Technologies for large-scale umbilical cord-derived MSC expansion: Experimental performance and cost of goods analysis.
Biochemical Engineering Journal
, 135
pp. 36-48.
10.1016/j.bej.2018.02.018.
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Farid, SS;
Jenkins, MJ;
(2018)
Bioprocesses for Cell Therapies.
In: Jagschies, G and Lindskog, E and Galliher, P, (eds.)
Biopharmaceutical Processing: Development, Design, and Implementation of Manufacturing Processes.
(pp. 899-930).
Elsevier: Amsterdam, Netherlands.
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Fazilah, Nurul Farhana;
Ariff, Arbakariya B;
Khayat, Mohd Ezuan;
Rios-Solis, Leonardo;
Halim, Murni;
(2018)
Influence of probiotics, prebiotics, synbiotics and bioactive phytochemicals on the formulation of functional yogurt.
Journal of Functional Foods
, 48
pp. 387-399.
10.1016/j.jff.2018.07.039.
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Field, Nicholas John;
(2018)
Investigation of multicomponent adsorption isotherms in chromatography using high-throughput formats.
Doctoral thesis (Ph.D), UCL (University College London).
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Forbes, N;
Hussain, MT;
Briuglia, ML;
Edwards, DP;
Horst, JHT;
Szita, N;
Perrie, Y;
(2018)
Rapid and scale-independent microfluidic manufacture of liposomes entrapping protein incorporating in-line purification and at-line size monitoring.
International Journal of Pharmaceutics
, 556
pp. 68-81.
10.1016/j.ijpharm.2018.11.060.
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Forte, N;
Livanos, M;
Miranda, E;
Morais, M;
Yang, X;
Rajkumar, VS;
Chester, KA;
... Baker, JR; + view all
(2018)
Tuning the Hydrolytic Stability of Next Generation Maleimide Cross-Linkers Enables Access to Albumin-Antibody Fragment Conjugates and tri-scFvs.
Bioconjugate Chemistry
, 29
(2)
pp. 486-492.
10.1021/acs.bioconjchem.7b00795.
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Fuldauer, L;
Parker, B;
Yaman, R;
Borrion, A;
(2018)
Managing anaerobic digestate from food waste in the urban environment: Evaluating the feasibility from an interdisciplinary perspective.
Journal of Cleaner Production
, 185
pp. 929-940.
10.1016/j.jclepro.2018.03.045.
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G
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Georgiou, M;
Reis, JND;
Wood, R;
Esteban, PP;
Roberton, V;
Mason, C;
Li, D;
... Wall, I; + view all
(2018)
Bioprocessing strategies to enhance the challenging isolation of neuro-regenerative cells from olfactory mucosa.
Scientific Reports
, 8
, Article 14440. 10.1038/s41598-018-32748-w.
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Goldrick, S;
Lee, K;
Spencer, C;
Holmes, W;
Kuiper, M;
Turner, R;
Farid, SS;
(2018)
On-line control of glucose concentration in high-yielding mammalian cell cultures enabled through oxygen transfer rate measurements.
Biotechnology Journal
, 13
(4)
, Article 1700607. 10.1002/biot.201700607.
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Goldrick, S;
Lovett, D;
Montague, G;
Lennox, B;
(2018)
Influence of Incident Wavelength and Detector Material Selection on Fluorescence in the Application of Raman Spectroscopy to a Fungal Fermentation Process.
Bioengineering
, 5
(4)
, Article 79. 10.3390/bioengineering5040079.
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Gruber, P;
Carvalho, F;
Marques, MPC;
O'Sullivan, B;
Subrizi, F;
Dobrijevic, D;
Ward, J;
... Szita, N; + view all
(2018)
Enzymatic synthesis of chiral amino-alcohols by coupling transketolase and transaminase-catalyzed reactions in a cascading continuous-flow microreactor system.
Biotechnology and Bioengineering
, 115
pp. 586-596.
10.1002/bit.26470.
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H
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Harrison, RP;
Medcalf, N;
Rafiq, QA;
(2018)
Cell therapy-processing economics: Small-scale microfactories as a stepping stone toward large-scale macrofactories.
Regenerative Medicine
, 13
(2)
pp. 159-173.
10.2217/rme-2017-0103.
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Harrison, RP;
Rafiq, QA;
Medcalf, N;
(2018)
Centralised versus decentralised manufacturing and the delivery of healthcare products: A United Kingdom exemplar.
Cytotherapy
, 20
(6)
pp. 873-890.
10.1016/j.jcyt.2018.05.003.
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Harrison, RP;
Ruck, S;
Rafiq, QA;
Medcalf, N;
(2018)
Decentralised manufacturing of cell and gene therapy products: Learning from other healthcare sectors.
Biotechnology Advances
, 36
(2)
pp. 345-357.
10.1016/j.biotechadv.2017.12.013.
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Hauck, NC;
Kirpach, J;
Kiefer, C;
Farinelle, S;
Maucourant, S;
Morris, SA;
Rosenberg, W;
... Lu, I-N; + view all
(2018)
Applying Unique Molecular Identifiers in Next Generation Sequencing Reveals a Constrained Viral Quasispecies Evolution under Cross-Reactive Antibody Pressure Targeting Long Alpha Helix of Hemagglutinin.
Viruses
, 10
(4)
, Article 148. 10.3390/v10040148.
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Heathman, TRJ;
Nienow, AW;
Rafiq, QA;
Coopman, K;
Kara, B;
Hewitt, CJ;
(2018)
Agitation and aeration of stirred-bioreactors for the microcarrier culture of human mesenchymal stem cells and potential implications for large-scale bioprocess development.
Biochemical Engineering Journal
, 136
pp. 9-17.
10.1016/j.bej.2018.04.011.
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Henriquez Morales, Maria-Jose;
(2018)
Synthetic Biology Routes To Production Of Chiral Amino-alcohols In Pichia Pastoris.
Doctoral thesis (Ph.D), UCL (University College London).
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Hirschmann, R;
Borodkin, N;
Baganz, F;
Hass, VC;
(2018)
Towards the integration of the anaerobic ethyl (S)-3-hydroxybutyrate production process into a biorefinery concept.
Chemical Engineering Transactions
, 70
pp. 559-564.
10.3303/CET1870094.
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I
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Isimite, J;
Baganz, F;
Hass, VC;
(2018)
Operator training simulators for biorefineries: current position and future directions.
Journal of Chemical Technology and Biotechnology
, 93
(6)
pp. 1529-1541.
10.1002/jctb.5583.
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J
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Jackson, David Shaun Frederick;
(2018)
Building a Synthetic Pathway For Nylon precursor Biosynthesis.
Doctoral thesis (Ph.D), UCL (University College London).
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Jenkins, Michael Joseph;
(2018)
Decisional tools for cost-effective bioprocess design for cell therapies and patient-specific drug discovery tools.
Doctoral thesis (Eng.D), UCL (University College London).
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Jenkins, MJ;
Farid, SS;
(2018)
Cost-effective bioprocess design for the manufacture of allogeneic CAR-T cell therapies using a decisional tool with multi-attribute decision-making analysis.
Biochemical Engineering Journal
, 137
pp. 192-204.
10.1016/j.bej.2018.05.014.
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Johnson, TF;
Bailey, JJ;
Iacoviello, F;
Welsh, JH;
Levison, PR;
Shearing, PR;
Bracewell, DG;
(2018)
Three dimensional characterisation of chromatography bead internal structure using X-ray computed tomography and focused ion beam microscopy.
Journal of Chromatography A
, 1566
pp. 79-88.
10.1016/j.chroma.2018.06.054.
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Jurlewicz, Kosma Michal;
(2018)
Use of high-throughput tools to optimise polishing-chromatography sequences for complex feed mixtures.
Doctoral thesis (Ph.D), UCL (University College London).
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K
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Khalife, Rana;
(2018)
The Effect of the nutritional microenvironment on stem cell differentiation.
Doctoral thesis (Ph.D), UCL (University College London).
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Khan, Haroon Dawood Sadullah;
(2018)
Towards development of a platform process for novel Lantiobic production.
Doctoral thesis (Eng.D), UCL (University College London).
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Khan, Muazzam Ali;
(2018)
Increasing the efficiency of antibody purification process by high throughput technology and intelligent design of experiment.
Doctoral thesis (Eng.D), UCL (University College London).
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Kilic, T;
Valinhas, ATDS;
Wall, I;
Renaud, P;
Carrara, S;
(2018)
Label-free detection of hypoxia-induced extracellular vesicle secretion from MCF-7 cells.
Scientific Reports
, 8
, Article 9402. 10.1038/s41598-018-27203-9.
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Konstantinidis, S;
Welsh, JP;
Titchener-Hooker, NJ;
Roush, DJ;
Velayudhan, A;
(2018)
Data‐driven multi‐objective optimization via grid compatible simplex technique and desirability approach for challenging high throughput chromatography applications.
Biotechnology Progress
, 34
(6)
10.1002/btpr.2673.
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Kühlbach, C;
da Luz, S;
Baganz, F;
Hass, VC;
Mueller, MM;
(2018)
A microfluidic system for the investigation of tumor cell extravasation.
Bioengineering
, 5
(2)
, Article 40. 10.3390/bioengineering5020040.
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L
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Lee, MJ;
Mantell, J;
Brown, IR;
Fletcher, JM;
Verkade, P;
Pickersgill, RW;
Woolfson, DN;
... Warren, MJ; + view all
(2018)
De novo targeting to the cytoplasmic and luminal side of bacterial microcompartments.
Nature Communications
, 9
, Article 3413. 10.1038/s41467-018-05922-x.
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Lee, MJ;
Mantell, J;
Hodgson, L;
Alibhai, D;
Fletcher, JM;
Brown, IR;
Frank, S;
... Warren, MJ; + view all
(2018)
Engineered synthetic scaffolds for organizing proteins within the bacterial cytoplasm.
Nature Chemical Biology
, 14
(2)
pp. 142-147.
10.1038/nchembio.2535.
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Leipold, L;
Dobrijevic, D;
Jeffries, J;
Bawn, M;
Moody, T;
Ward, J;
Hailes, HC;
(2018)
The identification and use of robust transaminases from a domestic drain metagenome.
RSC Green Chemistry
, 1
pp. 75-86.
10.1039/c8gc02986e.
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M
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McDonnell, T;
Artim-Esen, B;
Wincup, C;
Ripoll, VM;
Isenberg, D;
Giles, IP;
Rahman, A;
(2018)
Antiphospholipid Antibodies to Domain I of Beta-2-Glycoprotein I Show Different Subclass Predominance in Comparison to Antibodies to Whole Beta-2-glycoprotein I.
Frontiers in Immunology
, 9
(2224)
10.3389/fimmu.2018.02244.
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McDonnell, T;
Bradford, C;
Raj, D;
Ciurtin, C;
Jury, E;
Manson, J;
(2018)
Differential activation of complement in rheumatoid arthritis.
Presented at: Annual European Congress of Rheumatology - European League Against Rheumatism (EULAR) - 2018, Amsterdam, Netherlands.
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McDonnell, TCR;
Willis, R;
Pericleous, C;
Ripoll, VM;
Giles, IP;
Isenberg, DA;
Brasier, AR;
... Rahman, A; + view all
(2018)
PEGylated Domain I of Beta-2-Glycoprotein I Inhibits the Binding, Coagulopathic, and Thrombogenic Properties of IgG From Patients With the Antiphospholipid Syndrome.
Frontiers in Immunology
, 9
, Article 2413. 10.3389/fimmu.2018.02413.
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McDonnell, TCR;
Wincup, C;
Rahman, A;
Giles, I;
(2018)
Going viral in rheumatology: Using social media to show that mechanistic research is relevant to patients with lupus and antiphospholipid syndrome.
Rheumatology Advances in Practice
, 2
(1)
, Article rky003. 10.1093/rap/rky003.
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Melinek, Beatrice;
(2018)
Scale Down Mimics for Viral Vaccine Harvest and Early Purification.
Doctoral thesis (Eng.D), UCL (University College London).
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Melinek, BJ;
Dessoy, S;
Wright, B;
Bracewell, DG;
Mukhopadhyay, TK;
(2018)
Ultra scale-down approaches to study the centrifugal harvest for viral vaccine production.
Biotechnology and Bioengineering
, 115
(5)
pp. 1226-1238.
10.1002/bit.26546.
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Micheletti, M;
Rodriguez, G;
Ducci, A;
(2018)
Macro- and micro-scale mixing in a shaken bioreactor for fluids of high viscosity.
Chemical Engineering Research and Design
, 132
pp. 890-901.
10.1016/j.cherd.2018.01.018.
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Mitchell, SA;
Truscott, F;
Dickman, R;
Ward, J;
Tabor, AB;
(2018)
Simplified lipid II-binding antimicrobial peptides: Design, synthesis and antimicrobial activity of bioconjugates of nisin rings A and B with pore-forming peptides.
Bioorganic & Medicinal Chemistry
, 26
(21)
pp. 5691-5700.
10.1016/j.bmc.2018.10.015.
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Mukhopadhyay, A;
Basu, S;
Sinha, S;
Patra, H;
(2018)
Inner-View of Nanomaterial Incited Protein Conformational Changes: Insights into Designable Interaction.
[Review].
Research
, 2018
, Article 9712832. 10.1155/2018/9712832.
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N
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Newton, Joesph Matthew;
(2018)
Understanding cell lysis in fermentation and its impact on primary recovery using viscosity monitoring.
Doctoral thesis (Eng.D), UCL (University College London).
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Nweke, MC;
(2018)
Chromatography resin characterisation to analyse lifetime and performance during biopharmaceutical manufacture.
Doctoral thesis (Ph.D), UCL (University College London).
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Nweke, MC;
Rathore, AS;
Bracewell, DG;
(2018)
Lifetime and Aging of Chromatography Resins during Biopharmaceutical Manufacture.
[Editorial comment].
Trends in Biotechnology
, 36
(10)
pp. 992-995.
10.1016/j.tibtech.2018.01.001.
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O
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Oshinbolu, S;
Shah, R;
Finka, G;
Molloy, M;
Uden, M;
Bracewell, DG;
(2018)
Evaluation of fluorescent dyes to measure protein aggregation within mammalian cell culture supernatants.
Journal of Chemical Technology and Biotechnology
, 93
(3)
pp. 909-917.
10.1002/jctb.5519.
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Oshinbolu, S;
Wilson, LJ;
Lewis, W;
Shah, R;
Bracewell, DG;
(2018)
Measurement of impurities to support process development and manufacture of biopharmaceuticals.
TrAC Trends in Analytical Chemistry
, 101
pp. 120-128.
10.1016/j.trac.2017.10.026.
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Othman, M;
Ariff, AB;
Kapri, MR;
Rios-Solis, L;
Halim, M;
(2018)
Growth Enhancement of Probiotic Pediococcus acidilactici by Extractive Fermentation of Lactic Acid Exploiting Anion-Exchange Resin.
Frontiers in Microbiology
, 9
, Article 2554. 10.3389/fmicb.2018.02554.
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P
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Pallipurath Radhakrishnan, AN;
Marques, MPC;
Davies, MJ;
O'Sullivan, B;
Bracewell, DG;
Szita, N;
(2018)
Flocculation on a chip: a novel screening approach to determine floc growth rates and select flocculating agents.
Lab on a Chip
10.1039/C7LC00793K.
(In press).
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Pandya, A;
Howard, MJ;
Zloh, M;
Dalby, PA;
(2018)
An Evaluation of the Potential of NMR Spectroscopy and Computational Modelling Methods to Inform Biopharmaceutical Formulations.
Pharmaceutics
, 10
(4)
, Article 165. 10.3390/pharmaceutics10040165.
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Patel, N;
Bracewell, DG;
Sorensen, E;
(2018)
Dynamic modelling of aqueous two-phase systems to quantify the impact of bioprocess design, operation and variability.
Food and Bioproducts Processing
, 107
pp. 10-24.
10.1016/j.fbp.2017.10.005.
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Patel, Nehal;
(2018)
Development of aqueous two-phase separations by combining high-throughput screening and process modelling.
Doctoral thesis (Eng.D), UCL (University College London).
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Pathak, M;
Rathore, AS;
Lintern, K;
Bracewell, DG;
(2018)
Protein A chromatography resin lifetime—impact of feed composition.
Biotechnology Progress
, 34
(2)
pp. 412-419.
10.1002/btpr.2608.
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R
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Rafiq, QA;
Ruck, S;
Hanga, MP;
Heathman, TRJ;
Coopman, K;
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