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Number of items: 125.

Article

Affaticati, PE; Dai, SB; Payongsri, P; Hailes, HC; Tittmann, K; Dalby, PA; (2016) Structural Analysis of an Evolved Transketolase Reveals Divergent Binding Modes. Scientific Reports , 6 , Article 35716. 10.1038/srep35716.

Allison, AL; Ambrose-Dempster, E; Bawn, M; Casas Arredondo, M; Chau, C; Chandler, K; Dobrijevic, D; ... Ward, JM; + view all Allison, AL; Ambrose-Dempster, E; Bawn, M; Casas Arredondo, M; Chau, C; Chandler, K; Dobrijevic, D; Domenech Aparisi, T; Hailes, HC; Lettieri, P; Liu, C; Medda, F; Michie, S; Miodownik, M; Munro, B; Purkiss, D; Ward, JM; - view fewer (2021) The impact and effectiveness of the general public wearing masks to reduce the spread of pandemics in the UK: a multidisciplinary comparison of single-use masks versus reusable face masks. UCL Open Environment , 3 , Article 1. 10.14324/111.444/ucloe.000022.

Ambrose-Dempster, Esther; Leipold, Leona; Dobrijevic, Dragana; Bawn, Maria; Carter, Eve M; Stojanovski, Gorjan; Sheppard, Tom D; ... Hailes, Helen C; + view all Ambrose-Dempster, Esther; Leipold, Leona; Dobrijevic, Dragana; Bawn, Maria; Carter, Eve M; Stojanovski, Gorjan; Sheppard, Tom D; Jeffries, Jack WE; Ward, John M; Hailes, Helen C; - view fewer (2023) Mechanoenzymatic reactions for the hydrolysis of PET. RSC Advances , 13 (15) pp. 9954-9962. 10.1039/d3ra01708g.

Anselmi, Silvia; Ni, Yeke; Tonoli, Alessia; Wu, Jingyue; Wang, Yu; Prout, Luba; Miodownik, Mark; ... Hailes, Helen C; + view all Anselmi, Silvia; Ni, Yeke; Tonoli, Alessia; Wu, Jingyue; Wang, Yu; Prout, Luba; Miodownik, Mark; Jeffries, Jack WE; Hailes, Helen C; - view fewer (2025) The discovery of new metagenomic urethanases utilising a novel colorimetric assay for applications in the biodegradation of polyurethanes. Green Chemistry 10.1039/d5gc03560k. (In press).

Baud, Damien; Tappertzhofen, Nadine; Moody, Thomas S; Ward, John M; Hailes, Helen C; (2022) Stereoselective Transaminase-Mediated Synthesis of Serotonin and Melatonin Receptor Agonists. Advanced Synthesis & Catalysis 10.1002/adsc.202200146. (In press).

Baud, D; Jeffries, JWE; Moody, TS; Ward, JM; Hailes, HC; (2017) A metagenomics approach for new biocatalyst discovery: application to transaminases and the synthesis of allylic amines. Green Chemistry , 19 (4) pp. 1134-1143. 10.1039/c6gc02769e.

Baud, D; Ladkau, N; Moody, TS; Ward, JM; Hailes, HC; (2015) A rapid, sensitive colorimetric assay for the high-throughput screening of transaminases in liquid or solid-phase. Chemical Communications , 51 (97) pp. 17225-17228. 10.1039/c5cc06817g.

Bawn, M; Subrizi, F; Lye, GJ; Sheppard, TD; Hailes, HC; Ward, JM; (2018) One-pot, two-step transaminase and transketolase synthesis of L-gluco-heptulose from L-arabinose. Enzyme and Microbial Technology , 116 pp. 16-22. 10.1016/j.enzmictec.2018.05.006.

Bawn, M; Subrizi, F; Lye, GJ; Sheppard, TD; Hailes, HC; Ward, JM; (2018) Data on a thermostable enzymatic one-pot reaction for the production of a high-value compound from L-arabinose. Data in Brief , 19 pp. 1341-1354. 10.1016/j.dib.2018.05.140.

Bochenkova, AV; Mooney, CRS; Parkes, MA; Woodhouse, JL; Zhang, L; Lewin, R; Ward, JM; ... Fielding, HH; + view all Bochenkova, AV; Mooney, CRS; Parkes, MA; Woodhouse, JL; Zhang, L; Lewin, R; Ward, JM; Hailes, HC; Andersen, LH; Fielding, HH; - view fewer (2017) Mechanism of resonant electron emission from the deprotonated GFP chromophore and its biomimetics. Chemical Science , 8 (4) pp. 3154-3163. 10.1039/C6SC05529J.

Bofinger, R; Weitsman, G; Evans, R; Glaser, M; Sander, K; Allan, H; Hochhauser, D; ... Tabor, AB; + view all Bofinger, R; Weitsman, G; Evans, R; Glaser, M; Sander, K; Allan, H; Hochhauser, D; Kalber, TL; Årstad, E; Hailes, HC; Ng, T; Tabor, AB; - view fewer (2021) Drug delivery, biodistribution and anti-EGFR activity: theragnostic nanoparticles for simultaneous in vivo delivery of tyrosine kinase inhibitors and kinase activity biosensors. Nanoscale 10.1039/d1nr02770k. (In press).

Bofinger, R; Zaw-Thin, M; Mitchell, NJ; Patrick, PS; Stowe, C; Gomez-Ramirez, A; Hailes, HC; ... Tabor, AB; + view all Bofinger, R; Zaw-Thin, M; Mitchell, NJ; Patrick, PS; Stowe, C; Gomez-Ramirez, A; Hailes, HC; Kalber, TL; Tabor, AB; - view fewer (2018) Development of Lipopolyplexes for Gene Delivery: a Comparison of the Effects of Differing Modes of Targeting Peptide Display on the Structure and Transfection Activities of Lipopolyplexes. Journal of Peptide Science , 24 (12) , Article e3131. 10.1002/psc.3131.

Cárdenas-Fernández, M; Bawn, M; Hamley-Bennett, C; Bharat, PKV; Subrizi, F; Suhaili, N; Ward, DP; ... Lye, GJ; + view all Cárdenas-Fernández, M; Bawn, M; Hamley-Bennett, C; Bharat, PKV; Subrizi, F; Suhaili, N; Ward, DP; Bourdin, S; Dalby, PA; Hailes, HC; Hewitson, P; Ignatova, S; Kontoravdi, C; Leak, DJ; Shah, N; Sheppard, TD; Ward, JM; Lye, GJ; - view fewer (2017) An integrated biorefinery concept for conversion of sugar beet pulp into value-added chemicals and pharmaceutical intermediates. Faraday Discuss , 202 pp. 415-431. 10.1039/c7fd00094d.

Cárdenas-Fernández, M; Subrizi, F; Dobrijevic, D; Hailes, HC; Ward, JM; (2021) Characterisation of a hyperthermophilic transketolase from Thermotoga maritima DSM3109 as a biocatalyst for 7-keto-octuronic acid synthesis. Organic & Biomolecular Chemistry 10.1039/d1ob01237a. (In press).

Cárdenas‐Fernández, Max; Roddan, Rebecca; Carter, Eve M; Hailes, Helen C; Ward, John M; (2023) The Discovery of Imine Reductases and their Utilisation for the Synthesis of Tetrahydroisoquinolines. ChemCatChem 10.1002/cctc.202201126. (In press).

Carter, EM; Subrizi, F; Ward, JM; Sheppard, TD; Hailes, HC; (2021) Direct Conversion of Hydrazones to Amines using Transaminases. ChemCatChem 10.1002/cctc.202101008. (In press).

Coomber, CE; Laserna, V; Martin, LT; Smith, PD; Hailes, HC; Porter, MJ; Sheppard, TD; (2019) Catalytic direct amidations in tert-butyl acetate using B(OCH2CF3)3. Organic and Biomolecular Chemistry , 17 (26) pp. 6465-6469. 10.1039/c9ob01012b.

Cui, Lili; Kudsiova, Laila; Campbell, Frederick; Barlow, David J; Hailes, Helen C; Tabor, Alethea B; Lawrence, M Jayne; (2023) Understanding and optimising the transfection of lipopolyplexes formulated in saline: the effects of peptide and serum. Biomaterials Science 10.1039/d2bm01905a. (In press).

Demetriou, E; Story, HE; Bofinger, R; Hailes, HC; Tabor, AB; Golay, X; (2019) Effect of Liposomal Encapsulation on the Chemical Exchange Properties of Diamagnetic CEST Agents. The Journal of Physical Chemistry B , 123 (35) pp. 7545-7557. 10.1021/acs.jpcb.9b02280.

Deszcz, D; Affaticati, P; Ladkau, N; Gegel, A; Ward, JM; Hailes, HC; Dalby, PA; (2015) Single active-site mutants are sufficient to enhance serine:pyruvate α-transaminase activity in an ω-transaminase. The FEBS Journal , 282 (13) pp. 2512-2526. 10.1111/febs.13293.

Dobrijevic, D; Benhamou, L; Aliev, AE; Méndez-Sánchez, D; Dawson, N; Baud, D; Tappertzhofen, N; ... Ward, JM; + view all Dobrijevic, D; Benhamou, L; Aliev, AE; Méndez-Sánchez, D; Dawson, N; Baud, D; Tappertzhofen, N; Moody, TS; Orengo, CA; Hailes, HC; Ward, JM; - view fewer (2019) Metagenomic ene-reductases for the bioreduction of sterically challenging enones. RSC Advances , 9 (63) pp. 36608-36614. 10.1039/c9ra06088j.

Dobrijevic, D; Nematollahi, LA; Hailes, HC; Ward, JM; (2020) pET expression vector customized for efficient seamless cloning. Biotechniques 10.2144/btn-2020-0101.

Dunbabin, A; Subrizi, F; Ward, JM; Sheppard, TD; Hailes, HC; (2017) Furfurylamines from biomass: Transaminase catalysed upgrading of furfurals. Green Chemistry , 19 (2) pp. 397-404. 10.1039/c6gc02241c.

Erdmann, V; Lichmann, BR; Zhao, J; Simon, RC; Kroutil, W; Ward, JM; Hailes, HC; Erdmann, V; Lichmann, BR; Zhao, J; Simon, RC; Kroutil, W; Ward, JM; Hailes, HC; Rother, D; - view fewer (2017) Enzymatic and chemoenzymatic 3-step cascades for the synthesis of stereochemically complementary trisubstituted tetrahydroisoquinolines. Angewandte Chemie International Edition , 56 (41) pp. 12503-12507. 10.1002/anie.201705855.

Escot, Lorena; Gonzalez-Granda, Sergio; Méndez-Sánchez, Daniel; Wang, Yu; Hailes, Helen; Lavandera, Ivan; Gotor-Fernández, Vicente; (2024) β,β-Disubstituted Alkan-2-ones from Propargylic Alcohols Combining a Meyer-Schuster Rearrangement and Asymmetric Alkene Bioreduction. Advanced Synthesis & Catalysis , 366 (22) pp. 4737-4746. 10.1002/adsc.202400653.

Foster, RW; Benhamou, L; Porter, MJ; Bučar, DK; Hailes, HC; Tame, CJ; Sheppard, TD; (2015) Irreversible endo-selective diels-alder reactions of substituted alkoxyfurans: a general synthesis of endo-cantharimides. Chemistry , 21 (16) pp. 6107-6114. 10.1002/chem.201406286.

Foster, RW; Tame, CJ; Bučar, DK; Hailes, HC; Sheppard, TD; (2015) Sustainable Synthesis of Chiral Tetrahydrofurans through the Selective Dehydration of Pentoses. Chemistry , 21 (45) pp. 15947-15950. 10.1002/chem.201503510.

Foster, RW; Tame, CJ; Hailes, HC; Sheppard, TD; (2013) Highly Regioselective Synthesis of Substituted Isoindolinones via Ruthenium-Catalyzed Alkyne Cyclotrimerizations. Advanced Synthesis & Catalysis , 355 (11-12) 2353 -2360. 10.1002/adsc.201300055.

Galman, JL; Steadman, D; Bacon, S; Morris, P; Smith, MEB; Ward, JM; Dalby, PA; Galman, JL; Steadman, D; Bacon, S; Morris, P; Smith, MEB; Ward, JM; Dalby, PA; Hailes, HC; - view fewer (2010) alpha,alpha '-Dihydroxyketone formation using aromatic and heteroaromatic aldehydes with evolved transketolase enzymes. Chemical Communications , 46 (40) 7608 - 7610. 10.1039/c0cc02911d.

Gonzalez-Rodriguez, Jorge; Gonzalez-Granda, Sergio; Kumar, Hirdesh; Alvizo, Oscar; Escot, Lorena; Hailes, Helen C; Gotor-Fernandez, Vicente; Gonzalez-Rodriguez, Jorge; Gonzalez-Granda, Sergio; Kumar, Hirdesh; Alvizo, Oscar; Escot, Lorena; Hailes, Helen C; Gotor-Fernandez, Vicente; Lavandera, Ivan; - view fewer (2024) BioLindlar Catalyst: Ene-Reductase-Promoted Selective Bioreduction of Cyanoalkynes to Give (Z)-Cyanoalkenes. Angewandte Chemie International Edition , 63 (39) , Article e202410283. 10.1002/anie.202410283.

González‐Rodríguez, Jorge; González‐Granda, Sergio; Kumar, Hirdesh; Alvizo, Oscar; Escot, Lorena; Hailes, Helen C; Gotor‐Fernández, Vicente; González‐Rodríguez, Jorge; González‐Granda, Sergio; Kumar, Hirdesh; Alvizo, Oscar; Escot, Lorena; Hailes, Helen C; Gotor‐Fernández, Vicente; Lavandera, Iván; - view fewer (2024) BioLindlar Catalyst: Ene‐Reductase‐Promoted Selective Bioreduction of Cyanoalkynes to Give (Z)‐Cyanoalkenes. Angewandte Chemie , 136 (39) , Article e202410283. 10.1002/ange.202410283.

Greenwood, JB; Miles, J; De Camillis, S; Mulholland, P; Zhang, L; Parkes, MA; Hailes, HC; Greenwood, JB; Miles, J; De Camillis, S; Mulholland, P; Zhang, L; Parkes, MA; Hailes, HC; Fielding, HH; - view fewer (2014) Resonantly Enhanced Multiphoton Ionization Spectrum of the Neutral Green Fluorescent Protein Chromophore. JOURNAL OF PHYSICAL CHEMISTRY LETTERS , 5 (20) 3588 - 3592. 10.1021/jz5019256.

Gruber, P; Carvalho, F; Marques, MPC; O'Sullivan, B; Subrizi, F; Dobrijevic, D; Ward, J; ... Szita, N; + view all Gruber, P; Carvalho, F; Marques, MPC; O'Sullivan, B; Subrizi, F; Dobrijevic, D; Ward, J; Hailes, HC; Fernandes, P; Wohlgemuth, R; Baganz, F; Szita, N; - view fewer (2018) Enzymatic synthesis of chiral amino-alcohols by coupling transketolase and transaminase-catalyzed reactions in a cascading continuous-flow microreactor system. Biotechnology and Bioengineering , 115 pp. 586-596. 10.1002/bit.26470.

Guzman, JD; Pesnot, T; Barrera, DA; Davies, HM; McMahon, E; Evangelopoulos, D; Mortazavi, PN; ... Bhakta, S; + view all Guzman, JD; Pesnot, T; Barrera, DA; Davies, HM; McMahon, E; Evangelopoulos, D; Mortazavi, PN; Munshi, T; Maitra, A; Lamming, ED; Angell, R; Gershater, MC; Redmond, JM; Needham, D; Ward, JM; Cuca, LE; Hailes, HC; Bhakta, S; - view fewer (2015) Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase. J Antimicrob Chemother , 70 (6) pp. 1691-1703. 10.1093/jac/dkv010.

Hailes, Helen C; Wang, Yu; Li, Yiwen; Ni, Yeke; Bucar, Dejan-Kresimir; Dalby, Paul A; Ward, John M; Hailes, Helen C; Wang, Yu; Li, Yiwen; Ni, Yeke; Bucar, Dejan-Kresimir; Dalby, Paul A; Ward, John M; Jeffries, Jack; - view fewer (2024) A transaminase-mediated aldol reaction and applications in cascades to styryl pyridines. Catalysis Science & Technology 10.1039/d3cy01370g. (In press).

Hailes, H; Ward, J; Wang, Y; Tappertzhofen, N; Mendez-Sanchez, D; Bawn, M; Lyu, B; (2019) Design and use of de novo cascades for new benzylisoquinoline alkaloid biosynthesis. Angewandte Chemie , 58 (30) pp. 10120-10125. 10.1002/anie.201902761.

Hailes, HC; Subrizi, F; Benhamou, L; Ward, J; Sheppard, T; (2019) Aminopolyols from carbohydrates: the amination of sugars and sugar‐derived tetrahydrofurans with transaminases. Angewandte Chemie International Edition , 58 (12) pp. 3854-3858. 10.1002/anie.201813712.

Hayes, T; Hu, Y; Sanchez-Vazquez, SA; Hailes, HC; Aliev, AE; Evans, JRG; (2016) Strategies for synthesis of epoxy resins from oleic acid derived from food wastes. Journal of Polymer Science Part A: Polymer Chemistry , 54 (19) pp. 3159-3170. 10.1002/pola.28203.

Hickman, TWP; Baud, D; Benhamou, L; Hailes, HC; Ward, JM; (2020) Characterisation of four hotdog-fold thioesterases for their implementation in a novel organic acid production system. Applied Microbiology and Biotechnology , 104 pp. 4397-4406. 10.1007/s00253-020-10519-w.

Higson, S; Subrizi, F; Sheppard, TD; Hailes, HC; (2016) Chemical cascades in water for the synthesis of functionalized aromatics from furfurals. Green Chemistry , 18 (7) pp. 1855-1858. 10.1039/C5GC02935J.

Huang, W; Chen, W; Singh, V; Zhang, J; Wang, Y; Alabdullatif, M; Bele, E; ... Tiwari, MK; + view all Huang, W; Chen, W; Singh, V; Zhang, J; Wang, Y; Alabdullatif, M; Bele, E; Lye, GJ; Hailes, HC; Tiwari, MK; - view fewer (2025) Modulation-enabled healable and stretchable shape-memory polymer composites for digital light processing 4D printing. Additive Manufacturing , 101 , Article 104699. 10.1016/j.addma.2025.104699.

Jeffries, JWE; Dawson, N; Orengo, C; Moody, TS; Quinn, DJ; Hailes, HC; Ward, JM; (2016) Metagenome Mining: A Sequence Directed Strategy for the Retrieval of Enzymes for Biocatalysis. ChemistrySelect , 1 (10) pp. 2217-2220. 10.1002/slct.201600515.

Jockmann, Emely; Subrizi, Fabiana; Mohr, Michael KF; Carter, Eve M; Hebecker, Pia M; Popadić, Désirée; Hailes, Helen C; Jockmann, Emely; Subrizi, Fabiana; Mohr, Michael KF; Carter, Eve M; Hebecker, Pia M; Popadić, Désirée; Hailes, Helen C; Andexer, Jennifer N; - view fewer (2023) Expanding the Substrate Scope of N- and O-Methyltransferases from Plants for Chemoselective Alkylation. ChemCatChem , Article e202300930. 10.1002/cctc.202300930. (In press).

Karaluka, V; Murata, K; Masuda, S; Shiramatsu, Y; Kawamoto, T; Hailes, HC; Sheppard, TD; Karaluka, V; Murata, K; Masuda, S; Shiramatsu, Y; Kawamoto, T; Hailes, HC; Sheppard, TD; Kamimura, A; - view fewer (2018) Development of a microwave-assisted sustainable conversion of furfural hydrazones to functionalised phthalimides in ionic liquids. RSC Advances , 8 (40) pp. 22617-22624. 10.1039/c8ra03895c.

Kenny, GD; Bienemann, AS; Tagalakis, AD; Pugh, JA; Welser, K; Campbell, F; Tabor, AB; ... Hart, SL; + view all Kenny, GD; Bienemann, AS; Tagalakis, AD; Pugh, JA; Welser, K; Campbell, F; Tabor, AB; Hailes, HC; Gill, SS; Lythgoe, MF; McLeod, CW; White, EA; Hart, SL; - view fewer (2013) Multifunctional receptor-targeted nanocomplexes for the delivery of therapeutic nucleic acids to the brain. Biomaterials , 34 (36) pp. 9190-9200. 10.1016/j.biomaterials.2013.07.081.

Kenny, GD; Villegas-Llerena, C; Tagalakis, AD; Campbell, F; Welser, K; Botta, M; Tabor, AB; ... Hart, SL; + view all Kenny, GD; Villegas-Llerena, C; Tagalakis, AD; Campbell, F; Welser, K; Botta, M; Tabor, AB; Hailes, HC; Lythgoe, MF; Hart, SL; - view fewer (2012) Multifunctional receptor-targeted nanocomplexes for magnetic resonance imaging and transfection of tumours. Biomaterials , 33 (29) 7241 - 7250. 10.1016/j.biomaterials.2012.06.042.

Kudsiova, L; Mohammadi, A; Mustapa, MFM; Campbell, F; Welser, K; Vlaho, D; Story, H; ... Lawrence, MJ; + view all Kudsiova, L; Mohammadi, A; Mustapa, MFM; Campbell, F; Welser, K; Vlaho, D; Story, H; Barlow, DJ; Tabor, AB; Hailes, HC; Lawrence, MJ; - view fewer (2019) Trichain cationic lipids: the potential of their lipoplexes for gene delivery. Biomaterials Science , 7 (1) pp. 149-158. 10.1039/c8bm00965a.

Kudsiova, L; Welser, K; Campbell, F; Mohammadi, A; Dawson, N; Cui, L; Hailes, HC; ... Tabor, AB; + view all Kudsiova, L; Welser, K; Campbell, F; Mohammadi, A; Dawson, N; Cui, L; Hailes, HC; Lawrence, MJ; Tabor, AB; - view fewer (2016) Delivery of siRNA using ternary complexes containing branched cationic peptides: the role of peptide sequence, branching and targeting. Molecular BioSystems , 12 (3) pp. 934-951. 10.1039/c5mb00754b.

Lechner, H; Soriano, P; Poschner, R; Hailes, HC; Ward, JM; Kroutil, W; (2017) Library of norcoclaurine synthases and their immobilization for biocatalytic transformations. Biotechnology Journal 10.1002/biot.201700542. (In press).

Leipold, L; Dobrijevic, D; Jeffries, J; Bawn, M; Moody, T; Ward, J; Hailes, HC; (2018) The identification and use of robust transaminases from a domestic drain metagenome. RSC Green Chemistry , 1 pp. 75-86. 10.1039/c8gc02986e.

Lichman, BR; Gershater, MC; Lamming, ED; Pesnot, T; Sula, A; Keep, NH; Hailes, HC; Lichman, BR; Gershater, MC; Lamming, ED; Pesnot, T; Sula, A; Keep, NH; Hailes, HC; Ward, JM; - view fewer (2015) 'Dopamine-first' mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile. FEBS J , 282 (6) 1137 - 1151. 10.1111/febs.13208.

Lichman, BR; Lamming, ED; Pesnot, T; Smith, JM; Hailes, HC; Ward, JM; (2015) One-pot triangular chemoenzymatic cascades for the syntheses of chiral alkaloids from dopamine. Green Chemistry , 17 (2) pp. 852-855. 10.1039/c4gc02325k.

Lichman, BR; Lamming, ED; Pesnot, T; Smith, JM; Hailes, HC; Ward, JM; (2014) One-pot triangular chemoenzymatic cascades for the syntheses of chiral alkaloids from dopamine. Green Chemistry , 17 (2) pp. 852-855. 10.1039/c4gc02325k.

Lichman, BR; Sula, A; Pesnot, T; Hailes, HC; Ward, JM; Keep, NH; (2017) Structural Evidence for the Dopamine-First Mechanism of Norcoclaurine Synthase. Biochemistry , 56 (40) pp. 5274-5277. 10.1021/acs.biochem.7b00769.

Lichman, BR; Zhao, J; Hailes, HC; Ward, JM; (2017) Enzyme catalysed Pictet-Spengler formation of chiral 1,1 '-disubstituted- and spiro-tetrahydroisoquinolines. Nature Communications , 8 , Article 14883. 10.1038/ncomms14883.

Locks, A; Bowles, BJ; Brown, S; Hailes, HC; Hilton, ST; (2025) 3D Printing with tuneable degradation: Thiol-ene and thiol-yne containing formulations for biomedical applications. International Journal of Pharmaceutics , 674 , Article 125432. 10.1016/j.ijpharm.2025.125432.

Maitra, A; Evangelopoulos, D; Chrzastek, A; Martin, LT; Hanrath, A; Chapman, E; Hailes, HC; ... Bhakta, S; + view all Maitra, A; Evangelopoulos, D; Chrzastek, A; Martin, LT; Hanrath, A; Chapman, E; Hailes, HC; Lipman, M; McHugh, TD; Waddell, SJ; Bhakta, S; - view fewer (2020) Carprofen elicits pleiotropic mechanisms of bactericidal action with the potential to reverse antimicrobial drug resistance in tuberculosis. Journal of Antimicrobial Chemotherapy , Article dkaa307. 10.1093/jac/dkaa307.

Manunta, MDI; McAnulty, RJ; Tagalakis, AD; Bottoms, SE; Campbell, F; Hailes, HC; Tabor, AB; ... Hart, SL; + view all Manunta, MDI; McAnulty, RJ; Tagalakis, AD; Bottoms, SE; Campbell, F; Hailes, HC; Tabor, AB; Laurent, GJ; O'Callaghan, C; Hart, SL; - view fewer (2011) Nebulisation of Receptor-Targeted Nanocomplexes for Gene Delivery to the Airway Epithelium. PLOS ONE , 6 (10) , Article e26768. 10.1371/journal.pone.0026768.

Martin, Liam T; Daniel, Chris; Guldberg-Allen, Marcus; Navaratnarajah, Anushandan; Anselmi, Silvia; Burova, Tina-Maria D; Willcocks, Sam; ... Bhakta, Sanjib; + view all Martin, Liam T; Daniel, Chris; Guldberg-Allen, Marcus; Navaratnarajah, Anushandan; Anselmi, Silvia; Burova, Tina-Maria D; Willcocks, Sam; Hailes, Helen C; Bhakta, Sanjib; - view fewer (2025) Development of Carprofen analogues with activity against Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry , 127 , Article 118226. 10.1016/j.bmc.2025.118226.

Martin, Liam T; Lamming, Eleanor D; Maitra, Arundhati; Mortazavi, Parisa N; Roddan, Rebecca; Ward, John M; Bhakta, Sanjib; Martin, Liam T; Lamming, Eleanor D; Maitra, Arundhati; Mortazavi, Parisa N; Roddan, Rebecca; Ward, John M; Bhakta, Sanjib; Hailes, Helen C; - view fewer (2023) C-1 Substituted isoquinolines potentiate the antimycobacterial activity of rifampicin and ethambutol. Frontiers in Antibiotics , 2 , Article 1095013. 10.3389/frabi.2023.1095013.

McLaughlin, C; Assmann, M; Parkes, MA; Woodhouse, JL; Lewin, R; Hailes, HC; Worth, GA; McLaughlin, C; Assmann, M; Parkes, MA; Woodhouse, JL; Lewin, R; Hailes, HC; Worth, GA; Fielding, HH; - view fewer (2017) ortho and para chromophores of green fluorescent protein: controlling electron emission and internal conversion. Chemical Science , 8 (2) pp. 1621-1630. 10.1039/C6SC03833F.

Mitchell, N; Kalber, TL; Cooper, MS; Sunassee, K; Chalker, SL; Shaw, KP; Ordidge, KL; ... Tabor, AB; + view all Mitchell, N; Kalber, TL; Cooper, MS; Sunassee, K; Chalker, SL; Shaw, KP; Ordidge, KL; Badar, A; Janes, SM; Blower, PJ; Lythgoe, MF; Hailes, HC; Tabor, AB; - view fewer (2013) Incorporation of paramagnetic, fluorescent and PET/SPECT contrast agents into liposomes for multimodal imaging. Biomaterials , 34 (4) 1179 - 1192. 10.1016/j.biomaterials.2012.09.070.

Mohammadi, A; Kudsiova, L; Mustapa, MFM; Campbell, F; Vlaho, D; Welser, K; Story, H; ... Hailes, HC; + view all Mohammadi, A; Kudsiova, L; Mustapa, MFM; Campbell, F; Vlaho, D; Welser, K; Story, H; Tagalakis, AD; Hart, SL; Barlow, DJ; Tabor, AB; Lawrence, MJ; Hailes, HC; - view fewer (2019) The discovery and enhanced properties of trichain lipids in lipopolyplex gene delivery systems. Organic and Biomolecular Chemistry 10.1039/c8ob02374c.

Mooney, CRS; Parkes, MA; Zhang, L; Hailes, HC; Simperler, A; Bearpark, MJ; Fielding, HH; (2014) Competition between photodetachment and autodetachment of the 2(1)pi pi* state of the green fluorescent protein chromophore anion. JOURNAL OF CHEMICAL PHYSICS , 140 (20) , Article ARTN 205103. 10.1063/1.4874643.

Nasirudeen, MB; Hailes, HC; Evans, JRG; (2017) Preparation of 5-Hydroxymethylfurfural from Glucose and Fructose in Ionic Liquids by Reactive Vacuum Distillation Over a Solid Catalyst. Current Organic Synthesis , 14 (4) pp. 596-603. 10.2174/1570179414666161115155958.

Newgas, Sophie A; Jeffries, Jack WE; Moody, Thomas S; Ward, John M; Hailes, Helen C; (2021) Discovery of New Carbonyl Reductases Using Functional Metagenomics and Applications in Biocatalysis. Advanced Synthesis and Catalysis , 363 (12) pp. 3044-3052. 10.1002/adsc.202100199.

Ni, Yeke; Wang, Yu; Tabor, Alethea B; Ward, John M; Hailes, Helen C; (2023) The use of tyrosinases in a chemoenzymatic cascade as a peptide ligation strategy. RSC Chemical Biology 10.1039/d2cb00237j. (In press).

Payongsri, P; Steadman, D; Hailes, HC; Dalby, PA; (2015) Second generation engineering of transketolase for polar aromatic aldehyde substrates. Enzyme and Microbial Technology , 71 pp. 45-52. 10.1016/j.enzmictec.2015.01.008.

Payongsri, P; Steadman, D; Strafford, J; MacMurray, A; Hailes, HC; Dalby, PA; (2012) Rational substrate and enzyme engineering of transketolase for aromatics. Organic & Biomolecular Chemistry , 10 (45) 9021 - 9029. 10.1039/c2ob25751c.

Pennell, MN; Foster, RW; Turner, PG; Hailes, HC; Tame, CJ; Sheppard, TD; (2014) Gold catalysed synthesis of 3-alkoxyfurans at room temperature. Chemical Communications , 50 (11) 1302 - 1304. 10.1039/c3cc48290a.

Pesnot, T; Gershater, MC; Edwards, M; Ward, JM; Hailes, HC; (2017) One-Pot Phosphate-Mediated Synthesis of Novel 1,3,5-Trisubstituted Pyridinium Salts: A New Family of S. aureus Inhibitors. Molecules , 22 (4) , Article 626. 10.3390/molecules22040626.

Popadić, D; Mhaindarkar, D; Dang Thai, MHN; Hailes, HC; Mordhorst, S; Andexer, JN; (2021) A bicyclic S-adenosylmethionine regeneration system applicable with different nucleosides or nucleotides as cofactor building blocks. RSC Chemical Biology 10.1039/d1cb00033k. (In press).

Prout, Luba; Hailes, Helen C; Ward, John M; (2024) Natural transaminase fusions for biocatalysis. RSC Advances , 14 (6) pp. 4264-4273. 10.1039/d3ra07081f.

Richter, N; Simon, RC; Kroutil, W; Ward, JM; Hailes, HC; (2014) Synthesis of pharmaceutically relevant 17-α-amino steroids using an ω-transaminase. Chem Commun (Camb) , 50 pp. 6098-6100. 10.1039/c3cc49080g.

Richter, N; Simon, RC; Lechner, H; Kroutil, W; Ward, JM; Hailes, HC; (2015) ω-Transaminases for the amination of functionalised cyclic ketones. Organic & Biomolecular Chemistry , 13 (33) pp. 8843-8851. 10.1039/c5ob01204j.

Rios-Solis, L; Halim, M; Cazares, A; Morris, P; Ward, JM; Hailes, HC; Dalby, PA; ... Lye, GJ; + view all Rios-Solis, L; Halim, M; Cazares, A; Morris, P; Ward, JM; Hailes, HC; Dalby, PA; Baganz, F; Lye, GJ; - view fewer (2011) A toolbox approach for the rapid evaluation of multi-step enzymatic syntheses comprising a 'mix and match' E. coli expression system with microscale experimentation. Biocatalysis and Biotransformation , 29 (5) pp. 192-203. 10.3109/10242422.2011.609589.

Rios-Solis, L; Morris, P; Grant, C; Odeleye, AOO; Hailes, HC; Ward, JM; Dalby, PA; ... Lye, GJ; + view all Rios-Solis, L; Morris, P; Grant, C; Odeleye, AOO; Hailes, HC; Ward, JM; Dalby, PA; Baganz, F; Lye, GJ; - view fewer (2015) Modelling and optimisation of the one-pot, multi-enzymatic synthesis of chiral amino-alcohols based on microscale kinetic parameter determination. CHEMICAL ENGINEERING SCIENCE , 122 360 - 372. 10.1016/j.ces.2014.09.046.

Rizzo, Andrea; Aranda, Carmen; Galman, James; Alcasabas, Annette; Pandya, Akash; Bornadel, Amin; Costa, Bruna; ... Dominguez, Beatriz; + view all Rizzo, Andrea; Aranda, Carmen; Galman, James; Alcasabas, Annette; Pandya, Akash; Bornadel, Amin; Costa, Bruna; Hailes, Helen C; Ward, John M; Jeffries, Jack WE; Dominguez, Beatriz; - view fewer (2024) Broadening The Substrate Scope of Aldolases Through Metagenomic Enzyme Discovery. ChemBioChem , Article e202400278. 10.1002/cbic.202400278. (In press).

Roddan, R; Subrizi, F; Broomfield, J; Ward, JM; Keep, NH; Hailes, HC; (2021) Chemoenzymatic Cascades toward Methylated Tetrahydroprotoberberine and Protoberberine Alkaloids. Organic Letters , 23 (16) pp. 6342-6347. 10.1021/acs.orglett.1c02110.

Roddan, Rebecca; Carter, Eve M; Thair, Benjamin; Hailes, Helen C; (2022) Chemoenzymatic approaches to plant natural product inspired compounds. Natural Product Reports 10.1039/d2np00008c. (In press).

Roddan, R; Gygli, G; Sula, A; Mendez-Sanchez, D; Pleiss, J; Ward, JM; Keep, NH; Roddan, R; Gygli, G; Sula, A; Mendez-Sanchez, D; Pleiss, J; Ward, JM; Keep, NH; Hailes, HC; - view fewer (2019) Acceptance and Kinetic Resolution of α-Methyl-Substituted Aldehydes by Norcoclaurine Synthases. ACS Catalysis , 9 (10) pp. 9640-9649. 10.1021/acscatal.9b02699.

Roddan, R; Sula, A; Méndez-Sánchez, D; Subrizi, F; Lichman, BR; Broomfield, J; Richter, M; ... Hailes, HC; + view all Roddan, R; Sula, A; Méndez-Sánchez, D; Subrizi, F; Lichman, BR; Broomfield, J; Richter, M; Andexer, JN; Ward, JM; Keep, NH; Hailes, HC; - view fewer (2020) Single step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases. Communications Chemistry , 3 (1) 10.1038/s42004-020-00416-8. (In press).

Roddan, R; Ward, JM; Keep, NH; Hailes, HC; (2020) Pictet–Spenglerases in alkaloid biosynthesis: Future applications in biocatalysis. Current Opinion in Chemical Biology , 55 pp. 69-76. 10.1016/j.cbpa.2019.12.003.

Rowland, T; Hailes, HC; Evans, JRG; (2015) Sea salt as a potential ocean mirror material. RSC Advances , 5 (49) pp. 38926-38930. 10.1039/c5ra03469h.

Salinger, Matthew T; Castellano Garrido, Daniel; Lamming, Eleanor D; Ward, John M; Moody, Thomas S; Jeffries, Jack WE; Hailes, Helen C; (2024) An Alternative Cascade for the Selective Methylation of Catechols and Tetrahydroisoquinolines by O-Methyltransferases. ChemCatChem , 16 (7) , Article e202400492. 10.1002/cctc.202400492.

Salinger, Matthew T; Ward, John M; Moody, Thomas S; Jeffries, Jack WE; Hailes, Helen C; (2024) Bioalkylation Strategies to Synthesize Allylated Tetrahydroisoquinolines by Using Norcoclaurine Synthase and O-Methyltransferases. ChemCatChem , Article e202401668. 10.1002/cctc.202401668. (In press).

Sanchez-Vazquez, SA; Hailes, HC; Evans, JRG; (2013) Hydrophobic Polymers from Food Waste: Resources and Synthesis. POLYMER REVIEWS , 53 (4) 627 - 694. 10.1080/15583724.2013.834933.

Sanchez-Vazquez, SA; Sheppard, TD; Evans, JRG; Hailes, HC; (2014) The selective conversion of D-limonene to p,alpha-dimethylstyrene. RSC ADVANCES , 4 (106) 61652 - 61655. 10.1039/c4ra11558a.

Sayer, C; Martinez-Torres, RJ; Richter, N; Isupov, MN; Hailes, HC; Littlechild, JA; Ward, JM; (2014) The substrate specificity, enantioselectivity and structure of the (R)-selective amine : pyruvate transaminase from Nectria haematococca. FEBS JOURNAL , 281 (9) 2240 - 2253. 10.1111/febs.12778.

Sciscione, Fabiola; Guillaumé, Simon; Aliev, Abil E; Cook, Declan T; Bronstein, Hugo; Hailes, Helen C; Beard, Paul C; ... Tabor, Alethea B; + view all Sciscione, Fabiola; Guillaumé, Simon; Aliev, Abil E; Cook, Declan T; Bronstein, Hugo; Hailes, Helen C; Beard, Paul C; Kalber, Tammy L; Ogunlade, Olumide; Tabor, Alethea B; - view fewer (2023) EGFR-targeted semiconducting polymer nanoparticles for photoacoustic imaging. Bioorganic and Medicinal Chemistry , 91 , Article 117412. 10.1016/j.bmc.2023.117412.

Sciscione, Fabiola; Hailes, Helen C; Miodownik, Mark; (2023) The performance and environmental impact of pro-oxidant additive containing plastics in the open unmanaged environment—a review of the evidence. Royal Society Open Science , 10 (5) , Article 230089. 10.1098/rsos.230089.

Sciscione, Fabiola; Prout, Luba; Jeffries, Jack WE; Karam, Hajar J; Constantinou, Achilleas; Peng, Fei; Al-Salem, SM; ... Miodownik, Mark; + view all Sciscione, Fabiola; Prout, Luba; Jeffries, Jack WE; Karam, Hajar J; Constantinou, Achilleas; Peng, Fei; Al-Salem, SM; Hailes, Helen C; Miodownik, Mark; - view fewer (2025) Comparison of the behaviour of pro-oxidant additive containing plastic degradation in the unmanaged natural environment and in the laboratory. Royal Society Open Science , 12 (3) , Article 241270. 10.1098/rsos.241270.

Sehl, T; Hailes, HC; Ward, JM; Menyes, U; Pohl, M; Rother, D; (2014) Efficient 2-step biocatalytic strategies for the synthesis of all nor(pseudo) ephedrine isomers. Green Chemistry , 16 (6) pp. 3341-3348. 10.1039/c4gc00100a.

Sheppard, T; Hailes, H; Benhamou, L; Ward, D; Bucar, D-K; Lye, G; Foster, R; ... Sloan, L; + view all Sheppard, T; Hailes, H; Benhamou, L; Ward, D; Bucar, D-K; Lye, G; Foster, R; Tame, C; Wheelhouse, K; Sloan, L; - view fewer (2019) Functionalised tetrahydrofuran fragments from carbohydrates or sugar beet pulp biomass. Green Chemistry , 21 (8) pp. 2035-2042. 10.1039/C9GC00448C.

Stahl, T; Bofinger, R; Lam, I; Fallon, KJ; Johnson, P; Ogunlade, O; Vassileva, V; ... Tabor, AB; + view all Stahl, T; Bofinger, R; Lam, I; Fallon, KJ; Johnson, P; Ogunlade, O; Vassileva, V; Pedley, RB; Beard, PC; Hailes, HC; Bronstein, H; Tabor, AB; - view fewer (2017) Tunable Semiconducting Polymer Nanoparticles with INDT-Based Conjugated Polymers for Photoacoustic Molecular Imaging. Bioconjugate Chemistry , 28 (6) pp. 1734-1740. 10.1021/acs.bioconjchem.7b00185.

Stojanovski, Gorjan; Bawn, Maria; Locks, Amy; Ambrose-Dempster, Esther; Ward, John M; Jeffries, Jack WE; Hailes, Helen C; (2025) Functional Enrichment and Sequence-Based Discovery Identify Promiscuous and Efficient Poly Lactic Acid Degrading Enzymes. Environmental Science & Technology 10.1021/acs.est.4c07279.

Stojanovski, Gorjan; Hailes, Helen C; Ward, John M; (2022) Facile and selective N-alkylation of gentamicin antibiotics via chemoenzymatic synthesis. Green Chemistry 10.1039/d2gc03600b. (In press).

Stojanovski, G; Dobrijevic, D; Hailes, HC; Ward, JM; (2020) Identification and catalytic properties of new epoxide hydrolases from the genomic data of soil bacteria. Enzyme and Microbial Technology , 139 , Article 109592. 10.1016/j.enzmictec.2020.109592.

Strafford, J; Payongsri, P; Hibbert, EG; Morris, P; Batth, SS; Steadman, D; Smith, ME; ... Dalby, PA; + view all Strafford, J; Payongsri, P; Hibbert, EG; Morris, P; Batth, SS; Steadman, D; Smith, ME; Ward, JM; Hailes, HC; Dalby, PA; - view fewer (2012) Directed evolution to re-adapt a co-evolved network within an enzyme. Journal of Biotechnology , 157 (1) 237 - 245. 10.1016/j.jbiotec.2011.11.017.

Subrizi, F; Wang, Y; Thair, B; Méndez‐Sánchez, D; Roddan, R; Cárdenas‐Fernández, M; Siegrist, J; ... Hailes, HC; + view all Subrizi, F; Wang, Y; Thair, B; Méndez‐Sánchez, D; Roddan, R; Cárdenas‐Fernández, M; Siegrist, J; Richter, M; Andexer, JN; Ward, JM; Hailes, HC; - view fewer (2021) Multienzyme One-Pot Cascades Incorporating Methyltransferases for the Strategic Diversification of Tetrahydroisoquinoline Alkaloids. Angewandte Chemie International Edition , 60 (34) pp. 18673-18679. 10.1002/anie.202104476.

Subrizi, F; Wang, Y; Thair, B; Méndez‐Sánchez, D; Roddan, R; Cárdenas‐Fernández, M; Siegrist, J; ... Hailes, HC; + view all Subrizi, F; Wang, Y; Thair, B; Méndez‐Sánchez, D; Roddan, R; Cárdenas‐Fernández, M; Siegrist, J; Richter, M; Andexer, JN; Ward, JM; Hailes, HC; - view fewer (2021) Multienzyme One-Pot Cascades Incorporating Methyltransferases for the Strategic Diversification of Tetrahydroisoquinoline Alkaloids. Angewandte Chemie , 133 (34) pp. 18821-18827. 10.1002/ange.202104476.

Subrizi, F; Benhamou, L; Ward, JM; Sheppard, TD; Hailes, HC; (2019) Aminopolyols from Carbohydrates: Amination of Sugars and Sugar‐Derived Tetrahydrofurans with Transaminases. Angewandte Chemie , 131 (12) pp. 3894-3898. 10.1002/ange.201813712.

Subrizi, F; Cárdenas-Fernández, M; Lye, GJ; Ward, JM; Dalby, PA; Sheppard, TD; Hailes, HC; (2016) Transketolase catalysed upgrading of l -arabinose: the one-step stereoselective synthesis of l -gluco-heptulose. Green Chemistry , 18 (10) pp. 3158-3165. 10.1039/C5GC02660A.

Szpara, R; Goyder, A; Porter, MJ; Hailes, HC; Sheppard, TD; (2021) Regioselective Dehydration of Sugar Thioacetals under Mild Conditions. Organic Letters 10.1021/acs.orglett.1c00424. (In press).

Taneepanichskul, N.; Hailes, H.C.; Miodownik, M.; (2025) Using hyperspectral imaging and machine learning to identify food-contaminated compostable and recyclable plastics. UCL Open: Environment , 7 , Article 4. 10.14324/111.444/ucloe.3237.

Taneepanichskul, Nutcha; Hailes, Helen C; Miodownik, Mark; (2024) Using hyperspectral imaging to identify and classify large microplastic contamination in industrial composting processes. Frontiers in Sustainability , 5 , Article 1332163. 10.3389/frsus.2024.1332163.

Taneepanichskul, Nutcha; Hailes, Helen C; Miodownik, Mark; (2023) Automatic identification and classification of compostable and biodegradable plastics using hyperspectral imaging. Frontiers in Sustainability , 4 , Article 1125954. 10.3389/frsus.2023.1125954.

Tau, Omri; Henley, Alice; Boichenko, Anton N; Kleshchina, Nadezhda N; Riley, River; Wang, Bingxing; Winning, Danielle; ... Fielding, Helen H; + view all Tau, Omri; Henley, Alice; Boichenko, Anton N; Kleshchina, Nadezhda N; Riley, River; Wang, Bingxing; Winning, Danielle; Lewin, Ross; Parkin, Ivan P; Ward, John M; Hailes, Helen C; Bochenkova, Anastasia V; Fielding, Helen H; - view fewer (2022) Liquid-microjet photoelectron spectroscopy of the green fluorescent protein chromophore. Nature Communications , 13 (1) , Article 507. 10.1038/s41467-022-28155-5.

Tay, J; Parkes, MA; Addison, K; Chan, Y; Zhang, L; Hailes, HC; Bulman Page, PC; ... Fielding, HH; + view all Tay, J; Parkes, MA; Addison, K; Chan, Y; Zhang, L; Hailes, HC; Bulman Page, PC; Meech, SR; Blancafort, L; Fielding, HH; - view fewer (2017) The Effect of Conjugation on the Competition between Internal Conversion and Electron Detachment: A Comparison between Green Fluorescent and Red Kaede Protein Chromophores. The Journal of Physical Chemistry Letters , 8 pp. 765-771. 10.1021/acs.jpclett.7b00174.

Tonoli, A; Anselmi, S; Ward, JM; Hailes, HC; Jeffries, JWE; (2025) Expanding the Enzymatic Toolbox for Carboligation: Increasing the Diversity of the ‘Split’ Transketolase Sequence Space. ChemBioChem , Article e202401028. 10.1002/cbic.202401028. (In press).

Villegas-Torres, MF; Martinez-Torres, RJ; Cázares-Körner, A; Hailes, H; Baganz, F; Ward, J; (2015) Multi-step biocatalytic strategies for chiral amino alcohol synthesis. Enzyme and Microbial Technology , 81 pp. 23-30. 10.1016/j.enzmictec.2015.07.003.

Wang, Yu; Subrizi, Fabiana; Carter, Eve M; Sheppard, Tom D; Ward, John M; Hailes, Helen C; (2022) Enzymatic synthesis of benzylisoquinoline alkaloids using a parallel cascade strategy and tyrosinase variants. Nature Communications , 13 , Article 5436. 10.1038/s41467-022-33122-1.

Wang, Y; Tappertzhofen, N; Méndez‐Sánchez, D; Bawn, M; Lyu, B; Ward, JM; Hailes, HC; (2019) Design and Use of de novo Cascades for the Biosynthesis of New Benzylisoquinoline Alkaloids. Angewandte Chemie , 131 (30) pp. 10226-10231. 10.1002/ange.201902761.

Weber, Douglas; de Souza Bastos, Lucas; Winkler, Margit; Ni, Yeke; Aliev, Abil E; Hailes, Helen C; Rother, Doerte; (2023) Multi-enzyme catalysed processes using purified and whole-cell biocatalysts towards a 1,3,4-substituted tetrahydroisoquinoline. RSC Advances , 13 (15) pp. 10097-10109. 10.1039/d3ra01210g.

Weitsman, G; Mitchell, NJ; Evans, R; Cheung, A; Kalber, TL; Bofinger, R; Fruhwirth, GO; ... Ng, T; + view all Weitsman, G; Mitchell, NJ; Evans, R; Cheung, A; Kalber, TL; Bofinger, R; Fruhwirth, GO; Keppler, M; Wright, ZV; Barber, PR; Gordon, P; de Koning, T; Wulaningsih, W; Sander, K; Vojnovic, B; Ameer-Beg, S; Lythgoe, M; Arnold, JN; Årstad, E; Festy, F; Hailes, HC; Tabor, AB; Ng, T; - view fewer (2017) Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor. Oncogene , 36 pp. 3618-3628. 10.1038/onc.2016.522.

Woodhouse, JL; Henley, A; Lewin, R; Ward, JM; Hailes, HC; Bochenkova, AV; Fielding, HH; (2021) A photoelectron imaging study of the deprotonated GFP chromophore anion and RNA fluorescent tags. Physical Chemistry Chemical Physics 10.1039/d1cp01901e. (In press).

Yu, H; López, RIH; Steadman, D; Méndez-Sánchez, D; Higson, S; Cázares-Körner, A; Sheppard, TD; ... Dalby, PA; + view all Yu, H; López, RIH; Steadman, D; Méndez-Sánchez, D; Higson, S; Cázares-Körner, A; Sheppard, TD; Ward, JM; Hailes, HC; Dalby, PA; - view fewer (2020) Engineering transketolase to accept both unnatural donor and acceptor substrates and produce α‐hydroxyketones. The FEBS Journal , 287 (9) pp. 1758-1776. 10.1111/febs.15108.

Zaw Thin, M; Allan, H; Bofinger, R; Kostelec, TD; Guillaume, S; Connell, JJ; Patrick, PS; ... Kalber, TL; + view all Zaw Thin, M; Allan, H; Bofinger, R; Kostelec, TD; Guillaume, S; Connell, JJ; Patrick, PS; Hailes, HC; Tabor, AB; Lythgoe, MF; Stuckey, DJ; Kalber, TL; - view fewer (2020) Multi-modal imaging probe for assessing the efficiency of stem cell delivery to orthotopic breast tumours. Nanoscale 10.1039/d0nr03237a. (In press).

Zhao, J; Méndez-Sánchez, D; Roddan, R; Ward, JM; Hailes, HC; (2021) Norcoclaurine Synthase-Mediated Stereoselective Synthesis of 1,1'-Disubstituted, Spiro- and Bis-Tetrahydroisoquinoline Alkaloids. ACS Catalysis , 11 (1) pp. 131-138. 10.1021/acscatal.0c04704.

Zhao, J; Lichman, BR; Ward, JM; Hailes, HC; (2018) One-pot chemoenzymatic synthesis of trolline and tetrahydroisoquinoline analogues. Chemical Communications , 54 (11) pp. 1323-1326. 10.1039/c7cc08024g.

Zhao, J; Méndez-Sánchez, D; Ward, JM; Hailes, HC; (2019) Biomimetic Phosphate-Catalyzed Pictet–Spengler Reaction for the Synthesis of 1,1′-Disubstituted and Spiro-Tetrahydroisoquinoline Alkaloids. The Journal of Organic Chemistry , 84 (12) pp. 7702-7710. 10.1021/acs.joc.9b00527.

Proceedings paper

Santos, M; O'Sullivan, B; Müller, S; Bunescu, A; Baganz, F; Marques, MPC; Hailes, H; ... Wohlgemuth, R; + view all Santos, M; O'Sullivan, B; Müller, S; Bunescu, A; Baganz, F; Marques, MPC; Hailes, H; Szita, N; Wohlgemuth, R; - view fewer (2020) Chemoenzymatic microfluidic cascade reaction: Coupling of a diels-alder reaction with a transketolase-catalyzed reaction. In: MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences. (pp. pp. 693-694). CBMS: Online conference.

Thesis

Lamming, ED; (2015) Synthesis of N-heterocycles as anti-asthma drugs and compounds with antimycobacterial properties. Doctoral thesis , UCL (University College London).

Newgas, Sophie Alice; (2018) Biocatalysis using plant and metagenomic enzymes for organic synthesis. Doctoral thesis (Ph.D), UCL (University College London).

Rizzo, Andrea; (2025) Discovery and characterisation of C-C bond forming enzymes from genomic and metagenomic sources for applications in industrial biocatalysis. Doctoral thesis (Ph.D), UCL (University College London).

This list was generated on Sun Jan 18 13:50:11 2026 GMT.