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Chemoenzymatic approaches to plant natural product inspired compounds

Roddan, Rebecca; Carter, Eve M; Thair, Benjamin; Hailes, Helen C; (2022) Chemoenzymatic approaches to plant natural product inspired compounds. Natural Product Reports 10.1039/d2np00008c. (In press). Green open access

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Abstract

Complex molecules produced by plants have provided us with a range of medicines, flavour and fragrance compounds and pesticides. However, there are challenges associated with accessing these in an economically viable manner, including low natural abundance and the requirement for complex multi-step synthetic strategies. Chemoenzymatic approaches provide a valuable alternative strategy by combining traditional synthetic methods with biocatalysis. This review highlights recent chemoenzymatic syntheses towards plant natural products and analogues, focusing on the advantages of incorporating biocatalysts into a synthetic strategy.

Type: Article
Title: Chemoenzymatic approaches to plant natural product inspired compounds
Open access status: An open access version is available from UCL Discovery
DOI: 10.1039/d2np00008c
Publisher version: http://dx.doi.org/10.1039/d2np00008c
Language: English
Additional information: This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
UCL classification: UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Chemistry
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10146378
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