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Number of items: 318.

A

Abdallah, S; Benetos, E; Gold, NE; Hargreaves, S; Weyde, T; Wolff, D; (2016) Digital Music Lab: A Framework for Analysing Big Music Data. In: Proceedings of the 2016 24th European Signal Processing Conference (EUSIPCO). (pp. pp. 1118-1122). IEEE: Budapest, Hungary. Green open access
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Abdel-Gadir, A; Berber, R; Porter, JB; Quinn, PD; Suri, D; Kellman, P; Hart, AJ; ... Skinner, JA; + view all (2016) Detection of metallic cobalt and chromium liver deposition following failed hip replacement using T2* and R2 magnetic resonance. Journal of Cardiovascular Magnetic Resonance , 18 , Article 29. 10.1186/s12968-016-0248-z. Green open access
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Abdel-Gadir, A; Vorasettakarnkij, Y; Ngamkasem, H; Nordin, S; Ako, EA; Tumkosit, M; Sucharitchan, P; ... Moon, JC; + view all (2016) Ultrafast Magnetic Resonance Imaging for Iron Quantification in Thalassemia Participants in the Developing World The TIC-TOC Study (Thailand and UK International Collaboration in Thalassaemia Optimising Ultrafast CMR). Circulation , 134 (5) pp. 432-434. 10.1161/CIRCULATIONAHA.116.022803. Green open access
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Abdollah, MRA; (2016) Developing superparamagnetic iron oxide nanoparticles as targeted cancer nanomedicine. Doctoral thesis , UCL (University College London). Green open access
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Ako, EOI; Barber, N; Kowalik, G; Steeden, JA; Porter, J; Walker, J; Muthurangu, V; (2016) MR-Augmented Cardiopulmonary Exercise Testing - a proof of concept in Sickle Cell Disease. Presented at: Society for Cardiovascular Magnetic Resonance: 19th Annual SCMR Scientific Sessions, Los Angeles, California, USA. Green open access
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Alliouachene, S; Bilanges, B; Chaussade, C; Pearce, W; Foukas, LC; Scudamore, CL; Moniz, LS; (2016) Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice. Diabetologia , 59 (7) pp. 1503-1512. 10.1007/s00125-016-3963-y. Green open access
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Alzoubi, S; Brody, L; Rahman, S; Mahul-Mellier, AL; Mercado, N; Ito, K; El-Bahrawy, M; ... Hajji, N; + view all (2016) Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer. Oncotarget , 7 (28) pp. 44505-44521. 10.18632/oncotarget.9887. Green open access
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Amelina, H; Moiseeva, V; Collopy, LC; Pearson, SR; Armstrong, CA; Tomita, K; (2016) Sequential and counter-selectable cassettes for fission yeast. BMC Biotechnology , 16 , Article 76. 10.1186/s12896-016-0307-4. Green open access
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Aneke, JC; Huntley, N; Porter, J; Eleftheriou, P; (2016) Effect of automated red cell exchanges on oxygen saturation on-air, blood parameters and length of hospitalization in sickle cell disease patients with acute chest syndrome. Nigerian Medical Journal , 57 (3) pp. 190-193. 10.4103/0300-1652.184073. Green open access
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Ang, JE; Pandher, R; Ang, JC; Asad, YJ; Henley, A; Valenti, M; Box, G; ... Raynaud, FI; + view all (2016) Plasma metabolomic changes following PI3K inhibition as pharmacodynamic biomarkers: preclinical discovery to Phase I trial evaluation. Molecular Cancer Therapeutics , 15 (6) pp. 1412-1424. 10.1158/1535-7163.MCT-15-0815. Green open access
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Anguita, E; Gupta, R; Olariu, V; Valk, PJ; Peterson, C; Delwel, R; Enver, T; (2016) A somatic mutation of GFI1B identified in leukemia alters cell fate via a SPI1 (PU.1) centered genetic regulatory network. Developmental Biology , 411 (2) pp. 277-286. 10.1016/j.ydbio.2016.02.002. Green open access
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Anjos-Afonso, F; Loizou, JI; Bradburn, A; Kanu, N; Purewal, S; Da Costa, C; Bonnet, D; (2016) Perturbed hematopoiesis in mice lacking ATMIN. Blood , 128 (16) pp. 2017-2021. 10.1182/blood-2015-09-672980. Green open access
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Anthias, CN; (2016) Related haematopoietic progenitor cell donor care: the influence of current guidance, and pathways to improvement. Doctoral thesis , UCL (University College London). Green open access
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Arachchillage, DRJ; Mackie, IJ; Efthymiou, M; Chitolie, A; Hunt, BJ; Isenberg, DA; Khamashta, M; ... Cohen, H; + view all (2016) Rivaroxaban limits complement activation compared with warfarin in antiphospholipid syndrome patients with venous thromboembolism. Journal of Thrombosis and Haemostasis , 14 (11) pp. 2177-2186. 10.1111/jth.13475. Green open access
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Aref, S; Bailey, K; Fielding, A; (2016) Measles to the Rescue: A Review of Oncolytic Measles Virus. Viruses , 8 (10) 10.3390/v8100294. Green open access
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Arends, M; Wanner, C; Hughes, D; Mehta, A; Oder, D; Watkinson, OT; Elliott, PM; ... Hollak, CE; + view all (2016) Characterization of Classical and Nonclassical Fabry Disease: A Multicenter Study. Journal of the American Society of Nephrology , 28 (5) pp. 1631-1641. 10.1681/ASN.2016090964. Green open access
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Astle, WJ; Elding, H; Jiang, T; Allen, D; Ruklisa, D; Mann, AL; Mead, D; ... Soranzo, N; + view all (2016) The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Cell , 167 (5) pp. 1415-1429. 10.1016/j.cell.2016.10.042. Green open access
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Attard, G; Antonarakis, ES; (2016) Prostate cancer: AR aberrations and resistance to abiraterone or enzalutamide. Nature Reviews Urology , 13 (12) pp. 697-698. 10.1038/nrurol.2016.212. Green open access
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B

Bachanova, V; Weisdorf, DJ; Wang, T; Marsh, SG; Trachtenberg, E; Haagenson, MD; Spellman, SR; ... Cooley, SA; + view all (2016) Donor KIR B Genotype Improves Progression-Free Survival of Non-Hodgkin Lymphoma Patients Receiving Unrelated Donor Transplantation. Biology of Blood and Marrow Transplantation , 22 (9) pp. 1602-1607. 10.1016/j.bbmt.2016.05.016. Green open access
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Bangham, M; Goldstein, R; Walton, H; Ledermann, JA; (2016) Olaparib treatment for BRCA-mutant ovarian cancer with leptomeningeal disease. Gynecologic Oncology Reports , 18 pp. 22-24. 10.1016/j.gore.2016.10.004. Green open access
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Bartlett, TE; Chindera, K; McDermott, J; Breeze, CE; Cooke, WR; Jones, A; Reisel, D; ... Widschwendter, M; + view all (2016) Epigenetic reprogramming of fallopian tube fimbriae in BRCA mutation carriers defines early ovarian cancer evolution. Nature Communications , 7 , Article ARTN 116. 10.1038/ncomms11620. Green open access
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Beeken, RJ; Croker, H; Heinrich, M; Smith, L; Williams, K; Hackshaw, A; Hines, J; ... Fisher, A; + view all (2016) Study protocol for a randomised controlled trial of brief, habit-based, lifestyle advice for cancer survivors: exploring behavioural outcomes for the Advancing Survivorship Cancer Outcomes Trial (ASCOT). BMJ Open , 6 (11) , Article e011646. 10.1136/bmjopen-2016-011646. Green open access
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Behjati, S; Gundem, G; Wedge, DC; Roberts, ND; Tarpey, PS; Cooke, SL; Van Loo, P; ... Campbell, PJ; + view all (2016) Mutational signatures of ionizing radiation in second malignancies. Nature Communications , 7 , Article 12605. 10.1038/ncomms12605. Green open access
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Bell, LC; Pollara, G; Pascoe, M; Tomlinson, GS; Lehloenya, RJ; Roe, J; Meldau, R; ... Noursadeghi, M; + view all (2016) In Vivo Molecular Dissection of the Effects of HIV-1 in Active Tuberculosis. PLOS Pathogens , 12 (3) , Article e1005469. 10.1371/journal.ppat.1005469. Green open access
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Beltran, M; Yates, CM; Skalska, L; Dawson, M; Reis, FP; Viiri, K; Fisher, CL; ... Jenner, RG; + view all (2016) The interaction of PRC2 with RNA or chromatin is mutually antagonistic. Genome Research , 26 (7) pp. 896-907. 10.1101/gr.197632.115. Green open access
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Bendell, JC; Patel, MR; Yoshida, K; Seraj, J; Weaver, R; Lemech, C; Todaro, TG; ... Arkenau, H-T; + view all (2016) Phase 1 study of cardiac safety of TAS-102 in patients with advanced solid tumors. Cancer Chemother Pharmacol , 77 (6) pp. 1275-1283. 10.1007/s00280-016-3031-9. Green open access
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Benson, AB; Kiss, I; Bridgewater, J; Eskens, FALM; Sasse, C; Vossen, S; Chen, J; ... Krivoshik, A; + view all (2016) BATON-CRC: A Phase II Randomized Trial Comparing Tivozanib Plus mFOLFOX6 with Bevacizumab Plus mFOLFOX6 in Stage IV Metastatic Colorectal Cancer. Clinical Cancer Research , 22 (20) pp. 5058-5067. 10.1158/1078-0432.CCR-15-3117. Green open access
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Bentham, RB; (2016) A bioinfomatic analysis of the role of mitochondrial biogenesis in human pathologies. Doctoral thesis , UCL (University College London). Green open access
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Bentzen, AK; Marquard, AM; Lyngaa, R; Saini, SK; Ramskov, S; Donia, M; Such, L; ... Hadrup, SR; + view all (2016) Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes. Nature Biotechnology , 34 (10) pp. 1037-1045. 10.1038/nbt.3662. Green open access
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Bergerhoff, KF; (2016) Cellular and molecular events controlling acquisition of cytotoxic activity by melanoma-reactive CD4⁺ T cells in vivo. Doctoral thesis , UCL (University College London). Green open access
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Bhatnagar, G; Makanyanga, J; Ganeshan, B; Groves, A; Rodriguez-Justo, M; Halligan, S; Taylor, SA; (2016) MRI texture analysis parameters of contrast-enhanced T1-weighted images of Crohn's disease differ according to the presence or absence of histological markers of hypoxia and angiogenesis. Abdominal Radiology , 41 (7) pp. 1261-1269. 10.1007/s00261-016-0657-3. Green open access
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Blandford, A; Furniss, D; Lyons, I; Chumbley, G; Iacovides, I; Wei, L; Cox, A; ... Franklin, B; + view all (2016) Exploring the Current Landscape of Intravenous Infusion Practices and Errors (ECLIPSE): protocol for a mixed-methods observational study. BMJ Open , 6 , Article e009777. 10.1136/bmjopen-2015-009777. Green open access
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Bochtler, W; Gragert, L; Patel, ZI; Robinson, J; Steiner, D; Hofmann, JA; Pingel, J; ... Mueller, CR; + view all (2016) A comparative reference study for the validation of HLA-matching algorithms in the search for allogeneic hematopoietic stem cell donors and cord blood units. HLA , 87 (6) pp. 439-448. 10.1111/tan.12817. Green open access
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Bock, C; Halbritter, F; Carmona, FJ; Tierling, S; Datlinger, P; Assenov, Y; Berdasco, M; ... Zhang, K; + view all (2016) Quantitative comparison of DNA methylation assays for biomarker development and clinical applications. NATURE BIOTECHNOLOGY , 34 (7) pp. 726-737. 10.1038/nbt.3605. Green open access
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Braso-Maristany, F; Filosto, S; Catchpole, S; Marlow, R; Quist, J; Francesch-Domenech, E; Plumb, DA; ... Tutt, AN; + view all (2016) PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer. Nature Medicine , 22 (11) pp. 1303-1313. 10.1038/nm.4198. Green open access
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Breeze, CE; Paul, DS; van Dongen, J; Butcher, LM; Ambrose, JC; Barrett, JE; Lowe, R; ... Beck, S; + view all (2016) eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data. Cell Reports , 17 (8) pp. 2137-2150. 10.1016/j.celrep.2016.10.059. Green open access
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Bridgewater, J; Lopes, A; Beare, S; Duggan, M; Lee, D; Ricamara, M; McEntee, D; ... Valle, JW; + view all (2016) A phase 1b study of Selumetinib in combination with Cisplatin and Gemcitabine in advanced or metastatic biliary tract cancer: the ABC-04 study. BMC Cancer , 16 (1) p. 153. 10.1186/s12885-016-2174-8. Green open access
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Brimble, MA; Zhou, J; Morton, C; Meagher, M; Nathwani, AC; Gray, JT; Davidoff, AM; (2016) AAV Preparations Contain Contamination from DNA Sequences in Production Plasmids Directly Outside of the ITRs. Presented at: 19th Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT), Washington DC, USA. Green open access
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Brown, N; McBain, C; Nash, S; Hopkins, K; Sanghera, P; Saran, F; Phillips, M; ... Mulholland, P; + view all (2016) Multi-Center Randomized Phase II Study Comparing Cediranib plus Gefitinib with Cediranib plus Placebo in Subjects with Recurrent/Progressive Glioblastoma. PLoS ONE , 11 (5) 10.1371/journal.pone.0156369. Green open access
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Brown, S; Hinsley, S; Ballesteros, M; Bourne, S; McGarry, P; Sherratt, D; Flanagan, L; ... Myeloma UK Clinical Trials Network, .; + view all (2016) The MUK five protocol: a phase II randomised, controlled, parallel group, multi-centre trial of carfilzomib, cyclophosphamide and dexamethasone (CCD) vs. cyclophosphamide, bortezomib (Velcade) and dexamethasone (CVD) for first relapse and primary refractory multiple myeloma. BMC Hematology , 16 , Article 14. 10.1186/s12878-016-0053-9. Green open access
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Burrows, N; Cane, G; Robson, M; Gaude, E; J Howat, W; Szlosarek, PW; Pedley, RB; ... Maxwell, PH; + view all (2016) Hypoxia-induced nitric oxide production and tumour perfusion is inhibited by pegylated arginine deiminase (ADI-PEG20). Scientific Reports , 6 , Article 22950. 10.1038/srep22950. Green open access
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Butcher, LM; Ito, M; Brimpari, M; Morris, TJ; Soares, FA; Ährlund-Richter, L; Carey, N; ... Beck, S; + view all (2016) Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells. Nature Communications , 7 , Article 10458. 10.1038/ncomms10458. Green open access
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C

Campbell, J; Ryan, CJ; Brough, R; Bajrami, I; Pemberton, HN; Chong, IY; Costa-Cabral, S; ... Lord, CJ; + view all (2016) Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines. Cell Reports , 14 (10) pp. 2490-2501. 10.1016/j.celrep.2016.02.023. Green open access
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Cappellini, MD; Cassiman, D; Marinakis, T; Rosenbaum, H; Bauduer, F; Bjerrum, OW; Fraga, C; ... Villarrubia, J; + view all (2016) Investigating rare haematological disorders - A celebration of 10 years of the Sherlock Holmes symposia. European Oncology and Haematology , 12 (1) pp. 55-61. 10.17925/EOH.2016.12.01.55. Green open access
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Carter, T; Mulholland, P; Chester, K; (2016) Antibody-targeted nanoparticles for cancer treatment. Immunotherapy , 8 (8) pp. 941-958. 10.2217/imt.16.11. Green open access
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Carter, T; Shawy, H; Cohn-Brown, D; Chester, K; Mulholland, P; (2016) Ipilimumab and Bevacizumab in Glioblastoma. Clinical Oncology , 28 (10) pp. 622-626. 10.1016/j.clon.2016.04.042. Green open access
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Castillo, SD; Tzouanacou, E; Zaw-Thin, M; Berenjeno, IM; Parker, VE; Chivite, I; Milà-Guasch, M; ... Vanhaesebroeck, B; + view all (2016) Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans. Science Translational Medicine , 8 (332) , Article 332ra43. 10.1126/scitranslmed.aad9982. Green open access
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Castillo, SD; Vanhaesebroeck, B; Sebire, NJ; (2016) Phosphoinositide 3-kinase: a new kid on the block in vascular anomalies. The Journal of Pathology , 240 (4) pp. 387-396. 10.1002/path.4802. Green open access
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Caxaria, SMGL; (2016) Induced pluripotent stem cells (iPSCs) for research and therapy: induction of hepatic differentiation in iPSCs and evaluation of their quality as a model of in vivo development in the context of coagulation. Doctoral thesis , UCL (University College London). Green open access
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Chaganti, S; Illidge, T; Barrington, S; Mckay, P; Linton, K; Cwynarski, K; McMillan, A; ... British Committee for Standards in Haematology, British Committee for Standards in Haematology; + view all (2016) Guidelines for the management of diffuse large B-cell lymphoma. Br J Haematol , 174 (1) pp. 43-56. 10.1111/bjh.14136. Green open access
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Chakravarthy, A; Henderson, S; Thirdborough, SM; Ottensmeier, CH; Su, X; Lechner, M; Feber, A; ... Fenton, TR; + view all (2016) Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx. Journal Of Clinical Oncology , 34 (34) pp. 4132-4141. 10.1200/JCO.2016.68.2955. Green open access
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Chatterjee, M; Turner, DC; Felip, E; Lena, H; Cappuzzo, F; Horn, L; Garon, EB; ... Flotten, O; + view all (2016) Systematic evaluation of pembrolizumab dosing in patients with advanced non-small-cell lung cancer. Annals of Oncology , 27 (7) pp. 1291-1298. 10.1093/annonc/mdw174. Green open access
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Chen, L; Ge, B; Casale, FP; Vasquez, L; Kwan, T; Garrido-Martín, D; Watt, S; ... Soranzo, N; + view all (2016) Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells. Cell , 167 (5) 1398-1414.e24. 10.1016/j.cell.2016.10.026. Green open access
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Chen, Y; Breeze, CE; Zhen, S; Beck, S; Teschendorff, AE; (2016) Tissue-independent and tissue-specific patterns of DNA methylation alteration in cancer. Epigenetics & Chromatin , 9 , Article 10. 10.1186/s13072-016-0058-4. Green open access
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Chervova, O; Oksanen, L; (2016) Time reversal method with stabilizing boundary conditions for Photoacoustic tomography. Inverse Problems , 32 (12) , Article 125004. 10.1088/0266-5611/32/12/125004. Green open access
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Cheung, A; Bax, HJ; Josephs, DH; Ilieva, KM; Pellizzari, G; Opzoomer, J; Bloomfield, J; ... Karagiannis, SN; + view all (2016) Targeting folate receptor alpha for cancer treatment. Oncotarget , 7 (32) pp. 52553-52574. 10.18632/oncotarget.9651. Green open access
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Childs, A; Kirkwood, A; Edeline, J; Tu, VL; Watkins, J; Lamarca, A; Alrifai, D; ... Meyer, T; + view all (2016) Ki-67 index and response to chemotherapy in patients with neuroendocrine tumours. Endocrine-Related Cancer , 23 (7) pp. 563-570. 10.1530/ERC-16-0099. Green open access
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Childs, A; Vesely, C; Ensell, L; Lowe, H; Luong, TV; Caplin, ME; Toumpanakis, C; ... Meyer, T; + view all (2016) Expression of somatostatin receptors 2 and 5 in circulating tumour cells from patients with neuroendocrine tumours. British Journal of Cancer , 115 (12) pp. 1540-1547. 10.1038/bjc.2016.377. Green open access
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Chuang, LS; Villaverde, N; Hui, KY; Mortha, A; Rahman, A; Levine, AP; Haritunians, T; ... Cho, JH; + view all (2016) A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GMCSF. Gastroenterology , 151 (4) 710-723.e2. 10.1053/j.gastro.2016.06.045. Green open access
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Chung, R; Maulik, A; Hamarneh, A; Hochhauser, D; Hausenloy, DJ; Walker, JM; Yellon, DM; (2016) Effect of Remote Ischaemic Conditioning in ONCology patients undergoing chemotherapy: rationale and design of the ERIC-ONC study - a single-center, blinded, randomized controlled trial. Clinical Cardiology , 39 (2) pp. 72-82. 10.1002/clc.22507. Green open access
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Cohen, H; Hunt, BJ; Efthymiou, M; Arachchillage, DR; Mackie, IJ; Clawson, S; Sylvestre, Y; ... RAPS trial investigators, .; + view all (2016) Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised, controlled, open-label, phase 2/3, non-inferiority trial. Lancet Haematology , 3 (9) e426-e436. 10.1016/S2352-3026(16)30079-5. Green open access
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Cook, G; Ashcroft, AJ; Cairns, DA; Williams, CD; Brown, JM; Cavenagh, JD; Snowden, JA; ... National Cancer Research Institute Haemato-oncology Clinical Stu, .; + view all (2016) The effect of salvage autologous stem-cell transplantation on overall survival in patients with relapsed multiple myeloma (final results from BSBMT/UKMF Myeloma X Relapse [Intensive]): a randomised, open-label, phase 3 trial. Lancet Haematology , 3 (7) e340-e351. 10.1016/S2352-3026(16)30049-7. Green open access
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Cortés, E; Huidobro, PA; Sinclair, HG; Guldbrand, S; Peveler, WJ; Davies, T; Parrinello, S; ... Maier, SA; + view all (2016) Plasmonic Nanoprobes for Stimulated Emission Depletion Nanoscopy. ACS Nano , 10 (11) pp. 10454-10461. 10.1021/acsnano.6b06361. Green open access
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Coulter, TI; Chandra, A; Bacon, CM; Babar, J; Curtis, J; Screaton, N; Goodlad, JR; ... Cant, AJ; + view all (2016) Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study. J Allergy Clin Immunol 10.1016/j.jaci.2016.06.021. Green open access
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Crockford, AJ; (2016) Deciphering tetraploid tolerance. Doctoral thesis , UCL (University College London). Green open access
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Crowley, C; Klanrit, P; Butler, CR; Varanou, A; Platé, M; Hynds, RE; Chambers, RC; ... Janes, SM; + view all (2016) Surface modification of a POSS-nanocomposite material to enhance cellular integration of a synthetic bioscaffold. Biomaterials , 83 pp. 283-293. 10.1016/j.biomaterials.2016.01.005. Green open access
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D

Dangoor, A; Seddon, B; Gerrand, C; Grimer, R; Whelan, J; Judson, I; (2016) UK guidelines for the management of soft tissue sarcomas. Clinical Sarcoma Research , 6 , Article 20. 10.1186/s13569-016-0060-4. Green open access
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de Boer, SM; Powell, ME; Mileshkin, L; Katsaros, D; Bessette, P; Haie-Meder, C; Ottevanger, PB; ... Creutzberg, CL; + view all (2016) Toxicity and quality of life after adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): an open-label, multicentre, randomised, phase 3 trial. Lancet Oncology , 17 (8) pp. 1114-1126. 10.1016/S1470-2045(16)30120-6. Green open access
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De Ruysscher, D; Lueza, B; Le Péchoux, C; Johnson, DH; O'Brien, M; Murray, N; Spiro, S; ... RTT-SCLC Collaborative Group; + view all (2016) Impact of thoracic radiotherapy timing in limited-stage small-cell lung cancer: usefulness of the individual patient data meta-analysis. Annals of Oncology , 27 (10) pp. 1818-1828. 10.1093/annonc/mdw263. Green open access
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Dey, A; (2016) Enhancing the neutrophil-mediated anti-cancer response after oncolytic measles virus therapy in B cell malignancy: dissecting out the mechanism. Doctoral thesis , UCL (University College London). Green open access
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Dillon, M; Ellis, S; Grove, L; McLellan, L; Clack, G; Smith, S; Laude, J; ... Harrington, K; + view all (2016) PATRIOT: A phase I study to assess the tolerability, safety and biological effects of a specific ataxia telangiectasia and Rad3-related (ATR) inhibitor (AZD6738) as a single agent and in combination with palliative radiation therapy in patients with solid tumours. Presented at: ASCO 2016 Annual Meeting: Poster Session, Developmental Therapeutics - Clinical Pharmacology and Experimental Therapeutics, Chicago. Green open access
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Dirix, L; Swaisland, H; Verheul, HMW; Rottey, S; Leunen, K; Jerusalem, G; Rolfo, C; ... Plummer, R; + view all (2016) Effect of Itraconazole and Rifampin on the Pharmacokinetics of Olaparib in Patients With Advanced Solid Tumors: Results of Two Phase I Open-label Studies. Clinical Therapeutics , 38 (10) pp. 2286-2299. 10.1016/j.clinthera.2016.08.010. Green open access
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Domingo, E; Freeman-Mills, L; Rayner, E; Glaire, M; Briggs, S; Vermeulen, L; Fessler, E; ... Church, DN; + view all (2016) Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study. Lancet Gastroenterology and Hepatology , 1 (3) pp. 207-216. 10.1016/S2468-1253(16)30014-0. Green open access
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Dondelinger, Y; Darding, M; Bertrand, MJ; Walczak, H; (2016) Poly-ubiquitination in TNFR1-mediated necroptosis. Cellular Molecular Life Sciences , 73 (11) pp. 2165-2176. 10.1007/s00018-016-2191-4. Green open access
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Downes, RJ; Vassiliev, D; (2016) Spectral theoretic characterization of the massless Dirac action. Mathematika , 62 pp. 701-718. 10.1112/S0025579315000509. Green open access
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Drummond, CJ; Esfandiari, A; Liu, J; Lu, X; Hutton, C; Jackson, J; Bennaceur, K; ... Lunec, J; + view all (2016) TP53 mutant MDM2-amplified cell lines selected for resistance to MDM2-p53 binding antagonists retain sensitivity to ionizing radiation. Oncotarget , 7 (29) pp. 46203-46218. 10.18632/oncotarget.10073. Green open access
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Dvorkina, M; Nieddu, V; Chakelam, S; Pezzolo, A; Cantilena, S; Leite, AP; Chayka, O; ... Salomoni, P; + view all (2016) A promyelocytic leukemia protein-thrombospondin 2 axis and the risk of relapse in neuroblastoma. Clinical Cancer Research , 22 (13) pp. 3398-3409. 10.1158/1078-0432.CCR-15-2081. Green open access
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E

Ebinger, S; Oezdemir, EZ; Ziegenhain, C; Tiedt, S; Alves, CC; Grunert, M; Dworzak, M; ... Jeremias, I; + view all (2016) Characterization of Rare, Dormant, and Therapy-Resistant Cells in Acute Lymphoblastic Leukemia. Cancer Cell , 30 (6) pp. 849-862. 10.1016/j.ccell.2016.11.002. Green open access
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Esfandiari, A; Hawthorne, TA; Nakjang, S; Lunec, J; (2016) Chemical Inhibition of Wild-Type p53-Induced Phosphatase 1 (WIP1/PPM1D) by GSK2830371 Potentiates the Sensitivity to MDM2 Inhibitors in a p53-Dependent Manner. Molecular Cancer Therapeutics , 15 (3) pp. 379-391. 10.1158/1535-7163.MCT-15-0651. Green open access
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Flynn, MJ; (2016) Mechanistic and pharmacodynamic studies of ADCT-301, an Antibody Drug Conjugate targeting CD25-expressing haematological malignancies. Doctoral thesis , UCL (University College London).

Flynn, MJ; Zammarchi, F; Tyrer, PC; Akarca, AU; Janghra, N; Britten, CE; Havenith, CEG; ... Hartley, JA; + view all (2016) ADCT-301, a Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody-Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies. Molecular Cancer Therapeutics , 15 (11) pp. 2709-2721. 10.1158/1535-7163.MCT-16-0233. Green open access
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Richardson, SE; (2016) Modeling TEL-AML1 childhood acute lymphoblastic leukaemia using human pluripotent stem cells. Doctoral thesis , UCL (University College London). Green open access
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Roddie, C; (2016) Targeting interference of CTLA-4 co-inhibition to tumour specific T cells to enhance activity and reduce toxicity. Doctoral thesis , UCL (University College London). Green open access
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Rooshenas, L; Elliott, D; Wade, J; Jepson, M; Paramasivan, S; Strong, S; Wilson, C; ... POUT study group; + view all (2016) Conveying Equipoise during Recruitment for Clinical Trials: Qualitative Synthesis of Clinicians' Practices across Six Randomised Controlled Trials. PLoS Med , 13 (10) , Article e1002147. 10.1371/journal.pmed.1002147. Green open access
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Rowley, MI; Coolen, ACC; Vojnovic, B; Barber, PR; (2016) Correction: Robust Bayesian fluorescence lifetime estimation, decay model selection and instrument response determination for low-intensity FLIM imaging. PLoS ONE , 11 (8) , Article e0162224. 10.1371/journal.pone.0162224. Green open access
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Rowley, MI; Coolen, ACC; Vojnovic, B; Barber, PR; (2016) Robust Bayesian Fluorescence Lifetime Estimation, Decay Model Selection and Instrument Response Determination for Low-Intensity FLIM Imaging. PLoS One , 11 (6) , Article e0158404. 10.1371/journal.pone.0158404. Green open access
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Santos e Sousa, P; Ward, S; Lomas, C; Conlan, T; Shorrock, H; Means, TK; Plagnol, V; ... Bennett, CL; + view all (2016) A systems immunology approach to GVHD defines skin-autonomous control of donor T cells. Presented at: 2016 Keystone Symposia Conference: Immunity in Skin Development, Homeostasis and Disease, 28 February - 2 March 2016, Tahoe City, California, USA, Granlibakken, CA. Green open access
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Savas, P; Teo, ZL; Lefevre, C; Flensburg, C; Caramia, F; Alsop, K; Mansour, M; ... Loi, S; + view all (2016) The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE". PLoS Medicine , 13 (12) , Article e1002204. 10.1371/journal.pmed.1002204. Green open access
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Scelo, G; Hofmann, JN; Banks, RE; Bigot, P; Bhatt, RS; Cancel-Tassin, G; Chew, SK; ... Chanock, SJ; + view all (2016) International cancer seminars: a focus on kidney cancer. Annals of Oncology , 27 (8) pp. 1382-1385. 10.1093/annonc/mdw186. Green open access
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