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Article

Abel, GA; Gomez-Cano, M; Pham, TM; Lyratzopoulos, G; (2019) Reliability of hospital scores for the Cancer Patient Experience Survey: analysis of publicly reported patient survey data. BMJ Open , 9 (7) , Article e029037. 10.1136/bmjopen-2019-029037. Green open access
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Ahmed, S; Moore, DA; Nimmo, C; Nunn, AJ; Yates, TA; North London TB Journal Club; (2019) Linezolid for drug-susceptible tuberculosis. [Letter]. The Lancet Infectious Diseases , 19 (4) p. 357. 10.1016/S1473-3099(19)30110-0. Green open access
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Aicken, CRH; Wayal, S; Blomquist, PB; Fabiane, SM; Gerressu, M; Hughes, G; Mercer, CH; (2019) Pathways to, and use of, sexual healthcare among Black Caribbean sexual health clinic attendees in England: evidence from cross-sectional bio-behavioural surveys. BMC Health Services Research , 19 (1) , Article 668. 10.1186/s12913-019-4396-3. Green open access
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Al-Allaf, FA; Abduljaleel, Z; Athar, M; Taher, MM; Khan, W; Mehmet, H; Colakogullari, M; ... Bouazzaoui, A; + view all (2019) Modifying inter-cistronic sequence significantly enhances IRES dependent second gene expression in bicistronic vector: Construction of optimised cassette for gene therapy of familial hypercholesterolemia. Non-coding RNA Research , 4 (1) pp. 1-14. 10.1016/j.ncrna.2018.11.005. Green open access
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Allum, WH; Smyth, EC; Blazeby, JM; Grabsch, HI; Griffin, SM; Rowley, S; Cafferty, FH; ... Cunningham, D; + view all (2019) Quality assurance of surgery in the randomized ST03 trial of perioperative chemotherapy in carcinoma of the stomach and gastro‐oesophageal junction. BJS , 106 (9) pp. 1204-1215. 10.1002/bjs.11184. Green open access
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Antoniou, M; Kolamunnage-Dona, R; Wason, J; Bathia, R; Billingham, C; Bliss, JM; Brown, LC; ... Jorgensen, AL; + view all (2019) Biomarker-guided trials: Challenges in practice. Contemporary Clinical Trials Communications , 16 , Article 100493. 10.1016/j.conctc.2019.100493. Green open access
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Banerjee, G; Chan, E; Ambler, G; Wilson, D; Cipolotti, L; Shakeshaft, C; Cohen, H; ... Vahidassr, D; + view all (2019) Effect of small-vessel disease on cognitive trajectory after atrial fibrillation-related ischaemic stroke or TIA. Journal of Neurology , 266 (5) pp. 1250-1259. 10.1007/s00415-019-09256-6. Green open access
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Barber, PR; Weitsman, G; Lawler, K; Barrett, J; Rowley, M; Rodriguez-Justo, M; Fisher, D; ... Ng, T; + view all (2019) HER2-HER3 heterodimer quantification by FRET-FLIM and patient subclass analysis of the COIN colorectal trial. JNCI: Journal of the National Cancer Institute 10.1093/jnci/djz231. (In press). Green open access
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Barnes, J; Hunter, J; Harris, S; Shankar-Hari, M; Diouf, E; Jammer, I; Kalkman, C; ... Mythen, MG; + view all (2019) Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: infection and sepsis. British Journal of Anaesthesia , 122 (4) pp. 500-508. 10.1016/j.bja.2019.01.009. Green open access
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Bath, PM; Scutt, P; Anderson, CS; Ankolekar, S; Appleton, JP; Berge, E; Cala, L; ... Sprigg, N; + view all (2019) Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial. The Lancet , 393 (10175) pp. 1009-1020. 10.1016/S0140-6736(19)30194-1. Green open access
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Bath, PM; Woodhouse, LJ; Krishnan, K; Appleton, JP; Anderson, CS; Berge, E; Cala, L; ... Sprigg, N; + view all (2019) Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage. Stroke 10.1161/strokeaha.119.026389. Green open access
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Bazo-Alvarez, JC; Morris, TP; Carpenter, JR; Hayes, JF; Petersen, I; (2019) Effects of long-term antipsychotics treatment on body weight: A population-based cohort study. Journal of Psychopharmacology 10.1177/0269881119885918. (In press). Green open access
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Berger, N; Lewis, D; Quartagno, M; Njagi, EN; Cummins, S; (2019) Associations between school and neighbourhood ethnic density and physical activity in adolescents: evidence from the Olympic Regeneration in East London (ORiEL) study. Social Science & Medicine , 237 , Article 112426. 10.1016/j.socscimed.2019.112426. Green open access
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Berger, N; Lewis, D; Quartagno, M; Njagi, EN; Cummins, S; (2019) Longitudinal associations between perceptions of the neighbourhood environment and physical activity in adolescents: evidence from the Olympic Regeneration in East London (ORiEL) study. BMC Public Health , 19 , Article 1760. 10.1186/s12889-019-8003-7. Green open access
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Bernardino, JI; Mocroft, A; Wallet, C; de Wit, S; Katlama, C; Reiss, P; Mallon, PW; ... NEAT001/ANRS143 Trial Study Group; + view all (2019) Body composition and adipokines changes after initial treatment with darunavir-ritonavir plus either raltegravir or tenofovir disoproxil fumarate-emtricitabine: A substudy of the NEAT001/ANRS143 randomised trial. PLoS One , 14 (1) , Article e0209911. 10.1371/journal.pone.0209911. Green open access
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Blackshaw, H; Vennik, J; Philpott, C; Thomas, M; Eyles, C; Carpenter, J; Clarke, CS; ... Hopkins, C; + view all (2019) Expert panel process to optimise the design of a randomised controlled trial in chronic rhinosinusitis (the MACRO programme). Trials , 20 , Article 230. 10.1186/s13063-019-3318-3. Green open access
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Blagden, SP; Hamilton, AL; Mileshkin, L; Wong, S; Michael, A; Hall, M; Goh, JC; ... Gabra, H; + view all (2019) Phase IB Dose Escalation and Expansion Study of AKT Inhibitor Afuresertib with Carboplatin and Paclitaxel in Recurrent Platinum-resistant Ovarian Cancer. Clinical Cancer Research , 25 (5) pp. 1472-1478. 10.1158/1078-0432.CCR-18-2277. Green open access
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Blenkinsop, A; Choodari-Oskooei, B; (2019) Multiarm, multistage randomized controlled trials with stopping boundaries for efficacy and lack of benefit: An update to nstage. The Stata Journal , 19 (4) pp. 782-802. 10.1177/1536867X19893616. Green open access
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Blenkinsop, A; Parmar, MK; Choodari-Oskooei, B; (2019) Assessing the impact of efficacy stopping rules on the error rates under the multi-arm multi-stage framework. Clinical Trials 10.1177/1740774518823551. (In press). Green open access
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Bourke, C; Gough, E; Pimundu, G; Shonhai, A; Berejena, C; Terry, L; Baumard, L; ... Prendergast, AJ; + view all (2019) Cotrimoxazole reduces systemic inflammation in HIV infection by altering the gut microbiome and immune activation. Science Translational Medicine , 11 (486) , Article eaav0537. 10.1126/scitranslmed.aav0537. Green open access
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Brady, M; Rodger, A; Asboe, D; Cambiano, V; Clutterbuck, D; Desai, M; Field, N; ... Young, I; + view all (2019) BHIVA/BASHH guidelines on the use of HIV pre-exposure prophylaxis (PrEP) 2018. HIV Medicine , 20 (S2) S2-S80. 10.1111/hiv.12718. Green open access
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Brown, P; Tan, A-C; El-Esawi, MA; Liehr, T; Blanck, O; Gladue, DP; Almeida, GMF; ... Shalchyan, V; + view all (2019) Large expert-curated database for benchmarking document similarity detection in biomedical literature search. Database pp. 1-66. 10.1093/database/baz085. Green open access
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Buckley, MA; Woods, NT; Tyrer, JP; Mendoza-Fandiño, G; Lawrenson, K; Hazelett, DJ; Najafabadi, HS; ... Freedman, ML; + view all (2019) Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus. Cancer Research , 79 (3) pp. 467-481. 10.1158/0008-5472.CAN-17-3864. Green open access
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Bujkiewicz, S; Jackson, D; Thompson, JR; Turner, RM; Städler, N; Abrams, KR; White, IR; (2019) Bivariate network meta-analysis for surrogate endpoint evaluation. Statistics in Medicine 10.1002/sim.8187. Green open access
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Burdett, S; Boeve, L; Ingleby, F; Fisher, D; Rydzewska, L; Vale, C; van Andel, G; ... Tierney, J; + view all (2019) Prostate Radiotherapy for Metastatic Hormone-sensitive Prostate Cancer: A STOPCAP Systematic Review and Meta-analysis. European Urology 10.1016/j.eururo.2019.02.003. (In press). Green open access
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Burzykowski, T; Coart, E; Saad, ED; Shi, Q; Sommeijer, DW; Bokemeyer, C; Diaz-Rubio, E; ... Zalcberg, JR; + view all (2019) Evaluation of Continuous Tumor-Size-Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer. JAMA Network Open , 2 (9) , Article e1911750. 10.1001/jamanetworkopen.2019.11750. Green open access
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Butcher, E; Dezateux, C; Cortina-Borja, M; Knowles, RL; (2019) Prevalence of permanent childhood hearing loss detected at the universal newborn hearing screen: Systematic review and meta-analysis. PLoS One , 14 (7) , Article e0219600. 10.1371/journal.pone.0219600. Green open access
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Butcher, EJ; Dezateux, C; Knowles, R; (2019) Risk factors for permanent childhood hearing impairment. Archives of Disease in Childhood: Fetal & Neonatal 10.1136/archdischild-2018-315866. Green open access
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Bwakura-Dangarembizi, M; Amadi, B; Bourke, CD; Robertson, RC; Mwapenya, B; Chandwe, K; Kapoma, C; ... Prendergast, AJ; + view all (2019) Health Outcomes, Pathogenesis and Epidemiology of Severe Acute Malnutrition (HOPE-SAM): rationale and methods of a longitudinal observational study. BMJ Open , 9 (1) , Article e023077. 10.1136/bmjopen-2018-023077. Green open access
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Calaminus, G; Jenney, M; Hjorth, L; Baust, K; Bernstein, M; Bielack, S; Vos, PD; ... Nagarajan, R; + view all (2019) Quality of Life of Patients With Osteosarcoma in the European American Osteosarcoma Study-1 (EURAMOS-1): Development and Implementation of a Questionnaire Substudy. JMIR Research Protocols , 8 (9) , Article e14406. 10.2196/14406. Green open access
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Chan, MK; Goodall, R; Judd, A; Klein, N; Chiappini, E; Klimkait, T; Ngo-Giang-Huong, N; ... Babiker, AGA; + view all (2019) Predictors of faster virological suppression in early treated infants with perinatal HIV from Europe and Thailand. AIDS , 33 (7) pp. 1155-1165. 10.1097/QAD.0000000000002172. Green open access
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Chappell, E; Lyall, H; Riordan, A; Thorne, C; Foster, C; Butler, K; Prime, K; ... Collins, J; + view all (2019) The cascade of care for children and adolescents with HIV in the UK and Ireland, 2010 to 2016. Journal of the International AIDS Society , 22 (9) , Article e25379. 10.1002/jia2.25379. Green open access
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Cheng, SF; Brown, MM; Simister, R; Richards, T; (2019) The prevalence of carotid stenosis in patients presenting with ischaemic stroke: a one-year prospective observational study. British Journal of Surgery , 106 (7) pp. 872-878. 10.1002/bjs.11136. Green open access
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Cheng, SF; Zarkali, A; Richards, T; Simister, R; Chandratheva, A; (2019) Carotid artery stenosis, an underestimated cause of stroke recurrence in patients with ischaemic monocular visual loss. Annals of the Royal College of Surgeons of England , 101 (8) pp. 579-583. 10.1308/rcsann.2019.0071. Green open access
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Chiappini, E; Ene, L; Galli, L; Giaquinto, C; Goetghebuer, T; Judd, A; Malyuta, R; ... Thorne, C; + view all (2019) Severe haematologic toxicity is rare in high risk HIV-exposed infants receiving combination neonatal prophylaxis. HIV Medicine , 20 (5) pp. 291-307. 10.1111/hiv.12696. Green open access
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Clamp, AR; James, EC; McNeish, IA; Dean, A; Kim, J-W; O'Donnell, DM; Hook, J; ... Ledermann, JA; + view all (2019) Weekly dose-dense chemotherapy in first-line epithelial ovarian, fallopian tube, or primary peritoneal carcinoma treatment (ICON8): primary progression free survival analysis results from a GCIG phase 3 randomised controlled trial. The Lancet 10.1016/s0140-6736(19)32259-7. Green open access
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Clarke, NW; Ali, A; Ingleby, FC; Hoyle, A; Amos, CL; Attard, G; Brawley, CD; ... James, ND; + view all (2019) Addition of docetaxel to hormonal therapy in low- and high-burden metastatic hormone sensitive prostate cancer: long-term survival results from the STAMPEDE trial. Annals of Oncology 10.1093/annonc/mdz396. (In press). Green open access
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Clough, RE; Barillà, D; Delsart, P; Ledieu, G; Spear, R; Crichton, S; Mounier Vehier, C; ... Haulon, S; + view all (2019) Long-term Survival and Risk Analysis in 136 Consecutive Patients With Type B Aortic Dissection Presenting to a Single Centre Over an 11 Year Period. European Journal of Vascular and Endovascular Surgery , 57 (5) pp. 633-638. 10.1016/j.ejvs.2018.08.042. Green open access
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Collaborative Initiative for Paediatric HIV Education & Research, .; (2019) Incidence of switch to second-line antiretroviral therapy and associated factors in children with HIV: A global analysis. The Lancet HIV , 6 (2) e105-e115. 10.1016/S2352-3018(18)30319-9. Green open access
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Collins, I; Wools-Kaloustian, K; Goodall, R; Smith, C; Judd, A; The Collaborative Initiative for Paediatric HIV Education and Re, .; (2019) Incidence of switching to second-line antiretroviral therapy and associated factors in children with HIV: an international cohort collaboration. The Lancet HIV , 6 (2) e105-e115. 10.1016/S2352-3018(18)30319-9. Green open access
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Cook, JA; Julious, SA; Sones, W; Hampson, LV; Hewitt, C; Berlin, JA; Ashby, D; ... Vale, LD; + view all (2019) Practical help for specifying the target difference in sample size calculations for RCTs: the DELTA(2) five-stage study, including a workshop. Health Technology Assessment , 23 (60) pp. 1-88. 10.3310/hta23600. Green open access
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Copelyn, J; Thompson, LC; Le Prevost, M; Castro, H; Sturgeon, K; Rowson, K; Brice, S; ... Adolescents and Adults Living with Perinatal HIV (AALPHI) Steeri; + view all (2019) Self-harm in young people with perinatal HIV and HIV negative young people in England: cross sectional analysis. BMC Public Health , 19 (1) , Article 1165. 10.1186/s12889-019-7424-7. Green open access
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Cragg, WJ; Cafferty, F; Diaz-Montana, C; James, EC; Joffe, J; Mascarenhas, M; Yorke-Edwards, V; (2019) Early warnings and repayment plans: novel trial management methods for monitoring and managing data return rates in a multi-centre phase III randomised controlled trial with paper Case Report Forms. Trials , 20 (1) , Article 241. 10.1186/s13063-019-3343-2. Green open access
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Crichton, S; Belfrage, E; Collins, IJ; Doerholt, K; Judd, A; Le Coeur, S; Spoulou, V; ... Group authorship: The European Pregnancy and Paediatric HIV Coho, .; + view all (2019) Height and timing of growth spurt during puberty in young people living with vertically acquired HIV in Europe and Thailand. AIDS 10.1097/QAD.0000000000002294. (In press). Green open access
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Cro, S; Carpenter, JR; Kenward, MG; (2019) Information‐anchored sensitivity analysis: theory and application. Journal of the Royal Statistical Society: Series A (Statistics in Society) , 182 (2) pp. 623-645. 10.1111/rssa.12423. Green open access
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Crosbie, EJ; Ryan, NAJ; Arends, MJ; Bosse, T; Burn, J; Cornes, JM; Crawford, R; ... Evans, DG; + view all (2019) The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome. Genetics in Medicine 10.1038/s41436-019-0489-y. (In press). Green open access
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Cross, ELA; Sivyer, KA; Islam, J; Santillo, M; Mowbray, F; Peto, TEA; Walker, A; ... Llewelyn, M; + view all (2019) Adaptation and implementation of the ARK (Antibiotic Review Kit) Intervention to safely and substantially reduce antibiotic use in hospitals: A feasibility study. Journal of Hospital Infection , 103 (3) pp. 268-275. 10.1016/j.jhin.2019.07.017. Green open access
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Davey, RT; Fernández-Cruz, E; Markowitz, N; Pett, S; Babiker, AG; Wentworth, D; Khurana, S; ... INSIGHT FLU-IVIG Study Group; + view all (2019) Anti-influenza hyperimmune intravenous immunoglobulin for adults with influenza A or B infection (FLU-IVIG): a double-blind, randomised, placebo-controlled trial. The Lancet Respiratory Medicine , 7 (11) pp. 951-963. 10.1016/S2213-2600(19)30253-X. Green open access
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De Maio, N; Shaw, LP; Hubbard, A; George, S; Sanderson, ND; Swann, J; Wick, R; ... Stoesser, N; + view all (2019) Comparison of long-read sequencing technologies in the hybrid assembly of complex bacterial genomes. Microbial Genomics , 5 (9) 10.1099/mgen.0.000294. Green open access
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Dennis, ML; Benova, L; Abuya, T; Quartagno, M; Bellows, B; Campbell, OMR; (2019) Initiation and continuity of maternal healthcare: examining the role of vouchers and user-fee removal on maternal health service use in Kenya. Health Policy and Planning , Article czz004. 10.1093/heapol/czz004. (In press). Green open access
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Dheda, K; Gumbo, T; Maartens, G; Dooley, KE; Murray, M; Furin, J; Nardell, EA; ... Warren, RM; + view all (2019) The Lancet Respiratory Medicine Commission: 2019 update: epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant and incurable tuberculosis. The Lancet Respiratory Medicine , 7 (9) pp. 820-826. 10.1016/s2213-2600(19)30263-2. Green open access
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Diaz Montana, C; Cragg, W; Choudhury, R; Joffe, N; Sydes, M; Stenning, S; (2019) Implementing monitoring triggers and matching of triggered and control sites in the TEMPER study: A description and evaluation of a triggered monitoring management system. Trials , 20 , Article 227. 10.1186/s13063-019-3301-z. Green open access
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Dingle, K; Didelot, X; Quan, P; Eyre, DW; Stoesser, N; Marwick, C; Coia, J; ... Crook, D; + view all (2019) A role for tetracycline selection in recent evolution of the agriculture-associated Clostridium difficile PCR-ribotype 078. mBio , 10 (2) , Article e02790-18. 10.1128/mBio.02790-18. Green open access
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Donker, T; Smieszek, T; Henderson, KL; Walker, TM; Hope, R; Johnson, AP; Woodford, N; ... Robotham, JV; + view all (2019) Using hospital network-based surveillance for antimicrobial resistance as a more robust alternative to self-reporting. PLOS ONE , 14 (7) , Article e0219994. 10.1371/journal.pone.0219994. Green open access
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Donovan, J; Rohlwink, UK; Tucker, EW; Hiep, NTT; Thwaites, GE; Figaji, AA; Aarnoutse, RE; ... Wilkinson, RJ; + view all (2019) Checklists to guide the supportive and critical care of tuberculous meningitis [version 1; peer review: 2 approved]. Wellcome Open Research , 4 , Article 163. 10.12688/wellcomeopenres.15512.1. Green open access
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Dörk, T; Peterlongo, P; Mannermaa, A; Bolla, MK; Wang, Q; Dennis, J; Ahearn, T; ... Easton, DF; + view all (2019) Two truncating variants in FANCC and breast cancer risk. Scientific Reports , 9 (1) , Article 12524. 10.1038/s41598-019-48804-y. Green open access
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Dunn, DT; Glidden, DV; (2019) The Connection between the Averted Infections Ratio and the Rate Ratio in Active-control Trials of Pre-exposure Prophylaxis Agents. Statistical Communications in Infectious Diseases , 11 (1) , Article 20190006. 10.1515/scid-2019-0006. Green open access
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Durteste, M; Kyselyova, G; Volokha, A; Judd, A; Thorne, C; Cortina-Borja, M; Malyuta, R; ... Study of Young People Living with HIV in Ukraine, .; + view all (2019) Anxiety symptoms and felt stigma among young people living with perinatally or behaviourally-acquired HIV in Ukraine: A cross-sectional survey. PLoS One , 14 (1) , Article e0210412. 10.1371/journal.pone.0210412. Green open access
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Edwards, MR; Forbes, G; MacDonald, N; Berdunov, V; Mihaylova, B; Dias, P; Thomson, A; ... OPTIMISE II investigators, .; + view all (2019) Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usual care in patients undergoing major elective gastrointestinal surgery. BMJ Open , 9 , Article e023455. 10.1136/bmjopen-2018-023455. Green open access
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Embleton-Thirsk, A; Deane, E; Townsend, S; Farrelly, L; Popoola, B; Parker, J; Rustin, G; ... Kaplan, R; + view all (2019) Impact of retrospective data verification to prepare the ICON6 trial for use in a marketing authorization application. Clinical Trials , 16 (5) pp. 502-511. 10.1177/1740774519862528. Green open access
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Esmail, H; Lipman, MC; Nunn, A; Walker, TM; (2019) Individualising therapy for drug-sensitive tuberculosis. The Lancet Respiratory Medicine , 7 (10) pp. 834-835. 10.1016/S2213-2600(19)30247-4. Green open access
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Eyre, DW; Didelot, X; Buckley, AM; Freeman, J; Moura, I; Crook, D; Peto, TEA; ... Dingle, KE; + view all (2019) Clostridium difficile trehalose metabolism variants are common and not associated with adverse patient outcomes when variably present in the same lineage. EBioMedicine , 43 pp. 347-355. 10.1016/j.ebiom.2019.04.038. Green open access
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Eyre, DW; Peto, TEA; Crook, DW; Walker, AS; Wilcox, MH; (2019) Hash-based core genome multi-locus sequencing typing for Clostridium difficile. Journal of Clinical Microbiology 10.1128/JCM.01037-19. (In press). Green open access
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Eyre, DW; Shaw, R; Adams, H; Cooper, T; Crook, DW; Griffin, R-M; Mannion, P; ... Craine, N; + view all (2019) Whole-genome sequencing to determine the extent of Clostridium difficile transmission in a high incidence setting in North Wales in 2015. Journal of Antimicrobial Chemotherapy , 74 (4) pp. 1092-1100. 10.1093/jac/dky523. Green open access
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Farmer, RE; Ford, D; Mathur, R; Chaturvedi, N; Kaplan, R; Smeeth, L; Bhaskaran, K; (2019) Metformin use and risk of cancer in patients with type 2 diabetes: a cohort study of primary care records using inverse probability weighting of marginal structural models. International Journal of Epidemiology 10.1093/ije/dyz005. (In press). Green open access
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Fawcett, N; Young, B; Peto, L; Quan, TP; Gillot, R; Wu, J; Middlemass, C; ... Sandoe, JAT; + view all (2019) ‘Caveat emptor’: the cautionary tale of endocarditis and the potential pitfalls of clinical coding 1 data: an electronic health records study. BMC Medicine , 17 (169) 10.1186/s12916-019-1390-x. Green open access
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Femminella, GD; Frangou, E; Love, SB; Busza, G; Holmes, C; Ritchie, C; Lawrence, R; ... Edison, P; + view all (2019) Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer's disease: study protocol for a randomised controlled trial (ELAD study). Trials , 20 , Article 191. 10.1186/s13063-019-3259-x. Green open access
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Ferreira, MA; Gamazon, ER; Al-Ejeh, F; Aittomäki, K; Andrulis, IL; Anton-Culver, H; Arason, A; ... Chenevix-Trench, G; + view all (2019) Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer. Nature Communications , 10 , Article 1741. 10.1038/s41467-018-08053-5. Green open access
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Fidler, K; Foster, C; Lim, EJ; Patel, A; Welch, S; Menson, E; Klein, N; ... Collaborative HIV Paediatric Study (CHIPS) Steering Committee; + view all (2019) Reactivity of Routine HIV Antibody Tests in Children with Perinatally-Acquired HIV-1 in England: Cross Sectional Analysis. Pediatric Infectious Disease Journal , 38 (2) pp. 146-148. 10.1097/INF.0000000000002143. Green open access
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Figlioli, G; Bogliolo, M; Catucci, I; Caleca, L; Lasheras, SV; Pujol, R; Kiiski, JI; ... Durda, K; + view all (2019) The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer. NPJ Breast Cancer , 5 , Article 38. 10.1038/s41523-019-0127-5. Green open access
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Fitzgerald, FC; Lhomme, E; Harris, K; Kenny, J; Doyle, R; Kityo, C; Shaw, LP; ... CHAPAS-3 Trial Team; + view all (2019) Microbial translocation does not drive immune activation in Ugandan children with HIV. Journal of Infectious Diseases , 219 (1) pp. 89-100. 10.1093/infdis/jiy495. Green open access
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Folgori, L; Lutsar, I; Standing, JF; Walker, A; Roilides, E; Zaoutis, T; Jafri, H; ... Sharland, M; + view all (2019) Standardising neonatal and paediatric antibiotic clinical trial design and conduct: the PENTA-ID network view. BMJ Open , 9 (12) , Article e032592. 10.1136/bmjopen-2019-032592. Green open access
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Freeman, SC; Fisher, D; White, IR; Auperin, A; Carpenter, JR; (2019) Identifying inconsistency in network meta-analysis: Is the net heat plot a reliable method? Statistics in Medicine , 38 (29) pp. 5547-5564. 10.1002/sim.8383. Green open access
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Freriksen, JJM; van Seyen, M; Judd, A; Gibb, DM; Collins, IJ; Greupink, R; Russel, FGM; ... Burger, DM; + view all (2019) Review article: Direct-acting antivirals for the treatment of HCV during pregnancy and lactation: implications for maternal dosing, foetal exposure, and safety for mother and child. Alimentary Pharmacology and Therapeutics 10.1111/apt.15476. (In press). Green open access
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Gaba, F; Piek, J; Menon, U; Manchanda, R; (2019) Risk reducing early salpingectomy and delayed oophorectomy as a two staged alternative for primary prevention of ovarian cancer in increased risk women: a commentary. BJOG: An International Journal of Obstetrics and Gynaecology , 126 (7) pp. 831-839. 10.1111/1471-0528.15651. Green open access
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Galli, L; Crichton, S; Buzzoni, C; Goetghebuer, T; Jourdain, G; Judd, A; Klein, N; ... Goodall, R; + view all (2019) CD4 recovery following antiretroviral treatment interruptions in children and adolescents with HIV infection in Europe and Thailand. HIV Medicine 10.1111/hiv.12745. (In press). Green open access
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Gastine, S; Rashed, AN; Hsia, Y; Jackson, C; Barker, CIS; Mathur, S; Tomlin, S; ... Sharland, M; + view all (2019) GAPPS (Grading and Assessment of Pharmacokinetic-Pharmacodynamic Studies) a critical appraisal system for antimicrobial PKPD studies - development and application in pediatric antibiotic studies. Expert Review of Clinical Pharmacology , 12 (12) pp. 1091-1098. 10.1080/17512433.2019.1695600. Green open access
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Geary, B; Walker, MJ; Snow, JT; Lee, DCH; Pernemalm, M; Maleki-Dizaji, S; Azadbakht, N; ... Whetton, AD; + view all (2019) Identification of a Biomarker Panel for Early Detection of Lung Cancer Patients. Journal of Proteome Research , 18 (9) pp. 3369-3382. 10.1021/acs.jproteome.9b00287. Green open access
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George, E; Kiguli, S; Olupot Olupot, P; Opoka, R; Engoru, C; Akech, S; Nyeko, R; ... Walker, A; + view all (2019) Mortality risk over time after early fluid resuscitation in African children. Critical Care , 23 , Article 377. 10.1186/s13054-019-2619-y. Green open access
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Gilbert, DC; Vale, CL; (2019) Reply to Comments on "Increased risk of second cancers at sites associated with HPV after a prior HPV-associated malignancy, a systematic review and meta-analysis". British Journal of Cancer , 120 , Article 956. 10.1038/s41416-019-0440-7. Green open access
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Gilbert, DC; Wakeham, K; Langley, RE; Vale, CL; (2019) Increased risk of second cancers at sites associated with HPV after a prior HPV-associated malignancy, a systematic review and meta-analysi. British Journal of Cancer , 120 (2) pp. 256-268. 10.1038/s41416-018-0273-9. Green open access
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Glidden, DV; Mehrotra, ML; Dunn, DT; Geng, EH; (2019) Mosaic effectiveness: measuring the impact of novel PrEP methods. The Lancet HIV , 6 (11) e800-e806. 10.1016/S2352-3018(19)30227-9. Green open access
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Godolphin, PJ; Bath, PM; Algra, A; Berge, E; Brown, MM; Chalmers, J; Duley, L; ... Chen, C; + view all (2019) Outcome Assessment by Central Adjudicators Versus Site Investigators in Stroke Trials: A Systematic Review and Meta-Analysis. Stroke , 50 (8) pp. 2187-2196. 10.1161/STROKEAHA.119.025019. Green open access
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Godolphin, PJ; Bath, PM; Montgomery, AA; (2019) Short email with attachment versus long email without attachment when contacting authors to request unpublished data for a systematic review: a nested randomised trial. BMJ OPEN , 9 (1) , Article e025273. 10.1136/bmjopen-2018-025273. Green open access
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Godolphin, PJ; Godolphin, EJ; (2019) Robust assessment of two-treatment higher-order cross-over designs against missing values. Computational Statistics & Data Analysis , 132 pp. 31-45. 10.1016/j.csda.2018.06.020. Green open access
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Godolphin, PJ; Godolphin, EJ; (2019) Robustness of crossover trials against subject drop-out - Examples of perpetually connected designs. Statistical Methods in Medical Research , 28 (3) pp. 788-800. 10.1177/0962280217736541. Green open access
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González Martín, A; Oza, A; Embleton, AC; Pfisterer, J; Ledermann, J; Pujade-Lauraine, E; Kristensen, G; ... Perren, T; + view all (2019) Exploratory outcome analyses according to stage and/or residual disease in the ICON7 trial of carboplatin and paclitaxel with or without bevacizumab for newly diagnosed ovarian cancer. Gynecologic Oncology , 152 (1) 10.1016/j.ygyno.2018.08.036. Green open access
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Gossez, M; Martin, GE; Pace, M; Ramjee, G; Premraj, A; Kaleebu, P; Rees, H; ... SPARTAC Trial Investigators, .; + view all (2019) Virological remission after antiretroviral therapy interruption in female African HIV seroconverters. AIDS , 33 (2) pp. 185-197. 10.1097/QAD.0000000000002044. Green open access
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Grant, DJ; Manichaikul, A; Alberg, AJ; Bandera, EV; Barnholtz-Sloan, J; Bondy, M; Cote, ML; ... Schildkraut, JM; + view all (2019) Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women. Cancer Medicine 10.1002/cam4.1996. (In press). Green open access
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Gray, V; Briggs, S; Palles, C; Jaeger, E; Iveson, T; Kerr, R; Saunders, MP; ... Church, DN; + view all (2019) Pattern Recognition Receptor Polymorphisms as Predictors of Oxaliplatin Benefit in Colorectal Cancer. Journal of the National Cancer Institute 10.1093/jnci/djy215. (In press). Green open access
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Griffiths, GO; Cowan, R; Grigor, KM; Uscinska, BM; Sydes, MR; Russell, M; (2019) BA08: An open-label, single-arm, non-randomised, phase 2 trial of cisplatin, methotrexate and vinblastine (CMV) for pure squamous cell cancer of the urinary tract. PLoS One , 14 (1) , Article e0210785. 10.1371/journal.pone.0210785. Green open access
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Gupta, RK; Lipman, M; Jackson, C; Sitch, A; Southern, J; Drobniewski, F; Deeks, JJ; ... Abubakar, I; + view all (2019) Quantitative Interferon Gamma Release Assay and Tuberculin Skin Test Results to Predict Incident Tuberculosis: A Prospective Cohort Study. American Journal of Respiratory and Critical Care Medicine 10.1164/rccm.201905-0969OC. (In press). Green open access
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Gupta, RK; Rosenberg, G; Eriksen, J; Lipman, M; Jackson, C; Roy, A; Zenner, D; ... Abubakar, I; + view all (2019) Tuberculosis following renal transplantation in England, Wales and Northern Ireland: a national registry-based cohort study. European Respiratory Journal , 54 (4) , Article 1802245. 10.1183/13993003.02245-2018. Green open access
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Haddow, LJ; Godi, C; Sokolska, M; Cardoso, MJ; Oliver, R; Winston, A; Stöhr, W; ... Jäger, HR; + view all (2019) Brain Perfusion, Regional Volumes, and Cognitive Function in Human Immunodeficiency Virus–positive Patients Treated With Protease Inhibitor Monotherapy. Clinical Infectious Diseases , 68 (6) pp. 1031-1040. 10.1093/cid/ciy617. Green open access
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Hague, D; Townsend, S; Masters, L; Rauchenberger, M; Van Looy, N; Diaz Montana, C; Gannon, M; ... Sydes, M; + view all (2019) Changing platforms without stopping the train: experiences of data management and data management systems when adapting platform protocols by adding and closing comparisons. Trials , 20 , Article 294. 10.1186/s13063-019-3322-7. Green open access
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Haidari, G; Day, S; Wood, M; Ridgers, H; Cope, A; Fleck, S; Yan, C; ... Shattock, RJ; + view all (2019) The Safety and Immunogenicity of GTU (R) MultiHIV DNA Vaccine Delivered by Transcutaneous and Intramuscular Injection With or Without Electroporation in HIV-1 Positive Subjects on Suppressive ART. Frontiers in Immunology , 10 , Article 2911. 10.3389/fimmu.2019.02911. Green open access
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Harder, H; Starkings, RML; Fallowfield, LJ; Menon, U; Jacobs, IJ; Jenkins, VA; UKCTOCS trialists, .; (2019) Sexual functioning in 4,418 postmenopausal women participating in UKCTOCS: a qualitative free-text analysis. Menopause , 26 (10) pp. 1100-1109. 10.1097/GME.0000000000001377. Green open access
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Hollis, RL; Churchman, M; Michie, CO; Rye, T; Knight, L; McCavigan, A; Perren, T; ... Gourley, C; + view all (2019) High EMSY expression defines a BRCA-like subgroup of high-grade serous ovarian carcinoma with prolonged survival and hypersensitivity to platinum. Cancer 10.1002/cncr.32079. (In press). Green open access
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Hopkins, C; Williamson, E; Morris, S; Clarke, CS; Thomas, M; Evans, H; Little, P; ... MACRO programme team; + view all (2019) Antibiotic usage in chronic rhinosinusitis: analysis of national primary care electronic health records. Rhinology , 57 (6) pp. 420-429. 10.4193/Rhin19.136. Green open access
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HORNE, R; Glendinning, E; King, K; Chalder, T; Sabin, C; Walker, A; Campbell, L; ... Cooper, V; + view all (2019) Protocol of a two arm randomised, multi-centre, 12-month controlled trial: Evaluating the impact of a Cognitive Behavioural Therapy (CBT)-based intervention Supporting UPtake and Adherence to antiretrovirals (SUPA) in adults with HIV. BMC Public Health , 19 , Article 905. 10.1186/s12889-019-6893-z. Green open access
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Hostettler, IC; Bernal-Quiros, M; Wong, A; Sharma, N; Wilson, D; Seiffge, D; Shakeshaft, C; ... Houlden, H; + view all (2019) C9orf72 and intracerebral haemorrhage. Neurobiology of Aging , 84 237.e1-237.e3. 10.1016/j.neurobiolaging.2019.07.007. Green open access
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Houston, KA; Gibb, J; Olupot-Olupot, P; Obonyo, N; Mpoya, A; Nakuya, M; Muhindo, R; ... Maitland, K; + view all (2019) Gastroenteritis aggressive versus slow treatment for rehydration (GASTRO): a phase II rehydration trial for severe dehydration: WHO plan C versus slow rehydration. BMC Medicine , 17 (1) , Article 122. 10.1186/s12916-019-1356-z. Green open access
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Hoyle, AP; Ali, A; James, ND; Cook, A; Parker, CC; de Bono, JS; Attard, G; ... STAMPEDE Investigators; + view all (2019) Abiraterone in "High-" and "Low-risk" Metastatic Hormone-sensitive Prostate Cancer. European Urology , 76 (6) pp. 719-728. 10.1016/j.eururo.2019.08.006. Green open access
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Hsia, Y; Sharland, M; Jackson, C; Wong, ICK; Magrini, N; Bielicki, JA; (2019) Consumption of oral antibiotic formulations for young children according to the WHO Access, Watch, Reserve (AWaRe) antibiotic groups: an analysis of sales data from 70 middle-income and high-income countries. The Lancet Infectious Diseases , 19 (1) pp. 67-75. 10.1016/S1473-3099(18)30547-4. Green open access
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Indolfi, G; Bailey, H; Serranti, D; Giaquinto, C; Thorne, C; PENTAHep Study Group; (2019) Treatment and Monitoring of Children with Chronic Hepatitis C in the Pre-DAA Era: a European Survey of 38 Paediatric Specialists. Journal of Viral Hepatitis , 26 (8) pp. 961-968. 10.1111/jvh.13111. Green open access
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Jackson, C; Hsia, Y; Basmaci, R; Bielicki, J; Heath, PT; Versporten, A; Goossens, H; (2019) Global Divergence From World Health Organization Treatment Guidelines for Neonatal and Pediatric Sepsis. The Pediatric Infectious Disease Journal , 38 (11) pp. 1104-1106. 10.1097/inf.0000000000002433. Green open access
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Jackson, C; Hsia, Y; Bielicki, JA; Ellis, S; Stephens, P; Wong, ICK; Sharland, M; (2019) Estimating global trends in total and childhood antibiotic consumption, 2011-2015. BMJ Global Health , 4 (1) , Article e001241. 10.1136/bmjgh-2018-001241. Green open access
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Jin, Z; Collier, TS; Dai, DLY; Chen, V; Hollander, Z; Ng, RT; McManus, BM; ... Bystrom, C; + view all (2019) Development and Validation of Apolipoprotein AI-Associated Lipoprotein Proteome Panel for the Prediction of Cholesterol Efflux Capacity and Coronary Artery Disease. Clinical Chemistry , 65 (1) 10.1373/clinchem.2018.291922. Green open access
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Kelly, C; Mwandumba, HC; Heyderman, RS; Jambo, K; Kamng'ona, R; Chammudzi, M; Sheha, I; ... Khoo, S; + view all (2019) HIV-Related Arterial Stiffness in Malawian Adults Is Associated With the Proportion of PD-1–Expressing CD8⁺ T Cells and Reverses With Antiretroviral Therapy. Journal of Infectious Diseases , 219 (12) pp. 1948-1958. 10.1093/infdis/jiz015. Green open access
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Kerns, S; Other authors, M; Sydes, M; Other authors, MO; (2019) Radiogenomics Consortium Genome-Wide Association Study Meta-analysis of Late Toxicity after Prostate Cancer Radiotherapy. Journal of the National Cancer Institute , Article djz075. 10.1093/jnci/djz075. Green open access
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Kolakowska, A; Maresca, AF; Collins, IJ; Cailhol, J; (2019) Update on Adverse Effects of HIV Integrase Inhibitors. Current Treatment Options in Infectious Diseases , 11 pp. 372-387. 10.1007/s40506-019-00203-7. Green open access
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Kong, LY; Eyre, D; Corbeil, J; Raymond, F; Walker, AS; Wilcox, MH; Crook, DW; ... Loo, VG; + view all (2019) Clostridium difficile: Investigating Transmission Patterns Between Infected and Colonized Patients Using Whole Genome Sequencing. Clinical Infectious Diseases , 68 (2) pp. 204-209. 10.1093/cid/ciy457. Green open access
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Kyselyova, G; Martsynovska, V; Volokha, A; Nizova, N; Malyuta, R; Judd, A; Thorne, C; (2019) Young people in HIV care in Ukraine: a national survey on characteristics and service provision [version 1; peer review: 2 approved]. F1000Research , 8 , Article 323. 10.12688/f1000research.18573.1. Green open access
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Kyselyova, G; Martsynovska, V; Volokha, A; Nizova, N; Malyuta, R; Judd, A; Thorne, C; (2019) Young people in HIV care in Ukraine: a national survey on characteristics and service provision [version 2; peer review: 2 approved]. F1000Research , 8 , Article 323. 10.12688/f1000research.18573.2. Green open access
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Lancia, C; Anninga, J; Spitoni, C; Sydes, MR; Whelan, J; Hogendoorn, PCW; Gelderblom, H; (2019) Method to measure the mismatch between target and achieved received dose intensity of chemotherapy in cancer trials: a retrospective analysis of the MRC BO06 trial in osteosarcoma. BMJ Open , 9 (5) , Article e022980. 10.1136/bmjopen-2018-022980. Green open access
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Lancia, C; Anninga, JK; Sydes, M; Spitoni, C; Whelan, J; Hogendoorn, PCW; Gelderblom, H; (2019) A novel method to address the association between received dose intensity and survival outcome: benefits of approaching treatment intensification at a more individualised level in a trial of the European Osteosarcoma Intergroup. Cancer Chemotherapy and Pharmacology 10.1007/s00280-019-03797-3. (In press). Green open access
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Law, PJ; Timofeeva, M; Fernandez-Rozadilla, C; Broderick, P; Studd, J; Fernandez-Tajes, J; Farrington, S; ... Dunlop, MG; + view all (2019) Association analyses identify 31 new risk loci for colorectal cancer susceptibility. Nature Communications , 10 , Article 2154. 10.1038/s41467-019-09775-w. Green open access
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Lawrie, TA; Rogozińska, E; Sobiesuo, P; Vogel, JP; Ternent, L; Oladapo, OT; (2019) A systematic review of the cost‐effectiveness of uterotonic agents for the prevention of postpartum hemorrhage. International Journal of Gynecology & Obstetrics , 146 (1) pp. 56-64. 10.1002/ijgo.12836. Green open access
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Moore, CL; Stohr, W; Crook, AM; Richert, L; Lelievre, J-D; Pantaleo, G; Garcia, F; ... McCormack, S; + view all (2019) Multi-arm, multi-stage randomised controlled trials for evaluating therapeutic HIV cure interventions. Lancet HIV , 6 (5) e334-e340. 10.1016/S2352-3018(19)30082-7. Green open access
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Morris, TP; (2019) Stata tip 131: Custom legends for graphs that use translucency. The Stata Journal: Promoting communications on statistics and Stata , 19 (3) pp. 738-740. 10.1177/1536867x19874263. Green open access
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Morris, TP; Jarvis, CI; Cragg, W; Phillips, PPJ; Choodari-Oskooei, B; Sydes, MR; (2019) Proposals on Kaplan–Meier plots in medical research and a survey of stakeholder views: KMunicate. BMJ Open , 9 (9) , Article e030215. 10.1136/bmjopen-2019-030215. Green open access
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Morris, TP; White, I; Crowther, MJ; (2019) Using simulation studies to evaluate statistical methods. Statistics in Medicine , 38 (11) pp. 2074-2102. 10.1002/sim.8086. Green open access
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Müller, MD; Jongen, LM; Altinbas, A; Blackham, KA; Nederkoorn, PJ; Macdonald, S; Jäger, R; ... Bonati, LH; + view all (2019) Silent Intracerebral Hemorrhage in Patients Randomized to Stenting or Endarterectomy for Symptomatic Carotid Stenosis. Journal of Stroke , 21 (1) pp. 116-119. 10.5853/jos.2018.02838. Green open access
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Navani, N; Fisher, D; Tierney, JF; Stephens, RJ; Burdett, S; NSCLC Meta-analysis Collaborative Group, .; (2019) The accuracy of clinical staging of stage I-IIIa non-small cell lung cancer: An analysis based on individual participant data. Chest , 155 (3) pp. 502-509. 10.1016/j.chest.2018.10.020. Green open access
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Pham, TM; Carpenter, JR; Morris, TP; Wood, AM; Petersen, I; (2019) Population-calibrated Multiple Imputation for a Binary/categorical Covariate in Categorical Regression Models. Statistics in Medicine , 38 (5) pp. 792-808. 10.1002/sim.8004. Green open access
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Phillips, PPJ; Mitnick, CD; Neaton, JD; Nahid, P; Lienhardt, C; Nunn, AJ; (2019) Keeping phase III tuberculosis trials relevant: Adapting to a rapidly changing landscape. PLOS Medicine , 16 (3) , Article e1002767. 10.1371/journal.pmed.1002767. Green open access
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Quartagno, M; De Stavola, B; Emsley, R; Carpenter, JR; (2019) Effects of saline or albumin fluid bolus in resuscitation: major statistical flaws in the re-analysis of the FEAST trial. The Lancet Respiratory Medicine , 7 (7) pp. 581-593. 10.1016/S2213-2600(19)30114-6. Green open access
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Quartagno, M; De Stavola, B; Emsley, R; Carpenter, JR; (2019) Secondary re-analysis of the FEAST trial. [Letter]. The Lancet Respiratory Medicine , 7 (10) e30-e30. 10.1016/S2213-2600(19)30270-X. Green open access
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Quartagno, M; Goldstein, H; Carpenter, JR; (2019) Multiple Imputation with survey weights: a multilevel approach. Journal of Survey Statistics and Methodology , Article smz036. 10.1093/jssam/smz036. Green open access
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Quartagno, M; Grund, S; Carpenter, J; (2019) jomo: A Flexible Package for Two-level Joint Modelling Multiple Imputation. R Journal , 9 (1) Green open access
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Rashed, AN; Jackson, C; Gastine, S; Hsia, Y; Bielicki, J; Standing, JF; Tomlin, S; (2019) Pediatric pharmacokinetics of the antibiotics in the access and watch groups of the 2019 WHO model list of essential medicines for children: a systematic review. Expert Review of Clinical Pharmacology , 12 (12) pp. 1099-1106. 10.1080/17512433.2019.1693257. Green open access
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Rhodes, KM; Savović, J; Elbers, R; Jones, HE; Higgins, JPT; Sterne, JAC; Welton, NJ;