Browse by UCL people
Group by: Type | Date
Number of items: 139.
Article
100,000 Genomes Project Pilot Investigators;
Smedley, D;
Smith, KR;
Martin, A;
Thomas, EA;
McDonagh, EM;
Cipriani, V;
... Caulfield, M; + view all
(2021)
100,000 Genomes Pilot on Rare-Disease Diagnosis in Health Care — Preliminary Report.
New England Journal of Medicine
, 385
(20)
pp. 1868-1880.
10.1056/NEJMoa2035790.
|
Acosta-Herrera, M;
Kerick, M;
Gonzalez-Serna, D;
Wijmenga, C;
Franke, A;
Gregersen, PK;
Padyukov, L;
... Arnett, FC; + view all
(2019)
Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.
Annals of the Rheumatic Diseases
, 78
(3)
pp. 311-319.
10.1136/annrheumdis-2018-214127.
|
Allameen, NA;
Ramos-Lisbona, AI;
Wedderburn, LR;
Lundberg, IE;
Isenberg, DA;
(2025)
An update on autoantibodies in the idiopathic inflammatory myopathies.
Nature Reviews Rheumatology
, 21
(1)
pp. 46-62.
10.1038/s41584-024-01188-4.
|
Almeida, B;
Campanilho-Marques, R;
Arnold, K;
Pilkington, CA;
Wedderburn, LR;
Nistala, K;
Juvenile Dermatomyositis Research Group, .;
(2015)
Analysis of Published Criteria for Clinically Inactive Disease in a Large Juvenile Dermatomyositis Cohort Shows That Skin Disease Is Underestimated.
Arthritis & Rheumatology
, 67
(9)
pp. 2495-2502.
10.1002/art.39200.
|
Arthur, VL;
Shuldiner, E;
Remmers, EF;
Hinks, A;
Grom, AA;
Foell, D;
Martini, A;
... Ombrello, MJ; + view all
(2018)
IL1RN Variation Influences both Disease Susceptibility and Response to Human Recombinant IL-1RA Therapy in Systemic Juvenile Idiopathic Arthritis.
Arthritis & Rheumatology
, 70
(8)
pp. 1319-1330.
10.1002/art.40498.
|
Attrill, Meryl H;
Shinko, Diana;
Alexiou, Vicky;
Kartawinata, Melissa;
CHARMS study;
JIAP study;
Wedderburn, Lucy R;
(2024)
The immune landscape of the inflamed joint defined by spectral flow cytometry.
Clinical and Experimental Immunology
, 218
(3)
pp. 221-241.
10.1093/cei/uxae071.
|
Attrill, Meryl H;
Shinko, Diana;
Viveiros, Telma Martins;
Milighetti, Martina;
De Gruijter, Nina M;
Jebson, Bethany;
Kartawinata, Melissa;
... Pesenacker, Anne M; + view all
(2025)
Treg fitness signatures as a biomarker for disease activity in Juvenile Idiopathic Arthritis.
Journal of Autoimmunity
, 152
, Article 103379. 10.1016/j.jaut.2025.103379.
|
Beesley, Richard;
Luling Feilding, Freya;
CLUSTER Consortium Champions;
Rosser, Elizabeth C;
Shoop-Worrall, Stephanie JW;
McNeece, Alyssia;
Wanstall, Zoe;
... CLUSTER Consortium; + view all
(2023)
Development and implementation of ‘A guide to PPIE – Early Integration into Research Proposals’ in a multi-disciplinary consortium.
Rheumatology
, Article kead482. 10.1093/rheumatology/kead482.
(In press).
|
Bending, D;
Giannakopoulou, E;
Lom, H;
Wedderburn, LR;
(2015)
Synovial Regulatory T Cells Occupy a Discrete TCR Niche in Human Arthritis and Require Local Signals To Stabilize FOXP3 Protein Expression.
Journal of Immunology
, 195
(12)
pp. 5616-5624.
10.4049/jimmunol.1500391.
|
Bending, D;
Pesenacker, AM;
Ursu, S;
Wu, Q;
Lom, H;
Thirugnanabalan, B;
Wedderburn, LR;
(2014)
Hypomethylation at the Regulatory T Cell-Specific Demethylated Region in CD25hi T Cells Is Decoupled from FOXP3 Expression at the Inflamed Site in Childhood Arthritis.
J Immunol
, 193
(6)
pp. 2699-2708.
10.4049/jimmunol.1400599.
|
Binns, EL;
Moraitis, E;
Maillard, S;
Tansley, S;
McHugh, N;
Jacques, TS;
Wedderburn, LR;
... Nistala, K; + view all
(2017)
Effective induction therapy for anti-SRP associated myositis in childhood: A small case series and review of the literature.
Pediatric Rheumatology
, 15
, Article 77. 10.1186/s12969-017-0205-x.
|
Bolton, Chrissy;
Mahony, Christopher B;
Clay, Elizabeth;
Nisa, Patricia Reis;
Lomholt, Søren;
Hackland, Annie;
Chin, Paulynn S;
... Wu, Qiong; + view all
(2025)
Synovial tissue atlas in juvenile idiopathic arthritis reveals pathogenic niches associated with disease severity.
Science Translational Medicine
, 17
(805)
, Article eadt6050. 10.1126/scitranslmed.adt6050.
|
Boros, C;
McCann, L;
Simou, S;
Cancemi, D;
Ambrose, N;
Pilkington, CA;
Cortina-Borja, M;
(2022)
Juvenile Dermatomyositis: what comes next? Long-term outcomes in childhood myositis from a patient perspective.
Pediatric Rheumatology
, 20
, Article 102. 10.1186/s12969-022-00754-y.
|
Botta Gordon-Smith, Sophie;
Ursu, Simona;
Eaton, Simon;
Moncrieffe, Halima;
(2015)
Correlation of Low CD73 Expression on Synovial Lymphocytes With Reduced Adenosine Generation and Higher Disease Severity in Juvenile Idiopathic Arthritis.
Arthritis & Rheumatology
, 67
(2)
pp. 545-554.
10.1002/art.38959.
|
Brugha, Rossa;
Kirkham, Amanda;
Bate, Jessica;
Burke, GA Amos;
Hughes, Ana;
Magwaro, Sophia;
Pope, Ann M;
... OCTAVE-Minor Collaborative Groupˆ; + view all
(2025)
SARS-CoV-2-Specific Immune Responses to Vaccination in Children and Adolescents with Suppressed Immune Systems: A Prospective, Observational Study.
Journal of Pediatrics
, Article 114873. 10.1016/j.jpeds.2025.114873.
|
Cai, RA;
Beste, D;
Chaplin, H;
Varakliotis, S;
Suffield, L;
Josephs, F;
Sen, D;
... Eleftheriou, D; + view all
(2017)
Developing and Evaluating JIApp: Acceptability and Usability of a Smartphone App System to Improve Self-Management in Young People With Juvenile Idiopathic Arthritis.
JMIR Mhealth Uhealth
, 5
(8)
, Article e121. 10.2196/mhealth.7229.
|
Cai, RA;
Chaplin, H;
Livermore, P;
Lee, M;
Sen, D;
Wedderburn, LR;
Wilkinson, N;
... Eleftheriou, D; + view all
(2019)
Development of a benchmarking toolkit for adolescent and young adult rheumatology services (BeTAR).
Pediatric Rheumatology
, 17
, Article 23. 10.1186/s12969-019-0323-8.
|
Campanilho-Marques, R;
Almeida, B;
Deakin, C;
Arnold, K;
Gallot, N;
de Iorio, M;
Nistala, K;
... Juvenile Dermatomyositis Research Group, .; + view all
(2016)
Comparison of the Utility and Validity of Three Scoring Tools to Measure Skin Involvement in Patients With Juvenile Dermatomyositis.
Arthritis Care & Research
, 68
(10)
pp. 1514-1521.
10.1002/acr.22867.
|
Campanilho-Marques, R;
Deakin, CT;
Simou, S;
Papadopoulou, C;
Wedderburn, LR;
Pilkington, CA;
Juvenile Dermatomyositis Research Group (JDRG);
(2020)
Retrospective analysis of infliximab and
adalimumab treatment in a large cohort of
juvenile dermatomyositis patients.
Arthritis Research & Therapy
, 22
(1)
, Article 79. 10.1186/s13075-020-02164-5.
|
Chinoy, H;
Li, CK;
Platt, H;
Fertig, N;
Varsani, H;
Gunawardena, H;
Betteridge, Z;
... UK Adult Onset Myositis Immunogenetic Consortium and UK Juvenile; + view all
(2012)
Genetic association study of NF-κB genes in UK Caucasian adult and juvenile onset idiopathic inflammatory myopathy.
Rheumatology
, 51
(5)
794 -799.
10.1093/rheumatology/ker379.
|
Choida, V;
Hall-Craggs, M;
Jebson, B;
Leandro, M;
Fisher, C;
Wedderburn, L;
Ciurtin, C;
(2020)
Biomarkers of response to biologic therapy in juvenile idiopathic arthritis.
Frontiers in Pharmacology
10.3389/fphar.2020.635823.
(In press).
|
Cobb, J;
Cule, E;
Moncrieffe, H;
Hinks, A;
Ursu, S;
Patrick, F;
Kassoumeri, L;
... Thomson, W; + view all
(2014)
Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.
Pharmacogenomics Journal
, 14
(4)
pp. 356-364.
10.1038/tpj.2014.3.
|
Davies, R;
Carrasco, R;
Foster, HE;
Baildam, EM;
Chieng, ASE;
Davidson, JE;
Ioannou, Y;
... Hyrich, KL; + view all
(2016)
Treatment prescribing patterns in patients with juvenile idiopathic arthritis (JIA): Analysis from the UK Childhood Arthritis Prospective Study (CAPS).
Seminars in Arthritis and Rheumatism
, 46
pp. 190-195.
10.1016/j.semarthrit.2016.06.001.
|
De Iorio, M;
Gallot, N;
Valcarcel, B;
Wedderburn, L;
(2018)
A Bayesian semiparametric Markov regression model for juvenile dermatomyositis.
Statistics in Medicine
, 37
(10)
pp. 1711-1731.
10.1002/sim.7613.
|
Deakin, Claire T;
Bowes, John;
Rider, Lisa G;
Miller, Frederick W;
Pachman, Lauren M;
Sanner, Helga;
Rouster-Stevens, Kelly;
... Wedderburn, Lucy R; + view all
(2022)
Association with HLA-DRβ1 position 37 distinguishes juvenile Dermatomyositis from adult-onset myositis.
Human Molecular Genetics
10.1093/hmg/ddac019.
(In press).
|
Deakin, CT;
Cornish, GH;
Ng, KW;
Faulkner, N;
Bolland, W;
Hope, J;
Rosa, A;
... Kassiotis, G; + view all
(2021)
Favourable antibody responses to human coronaviruses in children and adolescents with autoimmune rheumatic diseases.
Med
, 2
(9)
1093-1106.e6.
10.1016/j.medj.2021.08.001.
|
Deakin, CT;
Campanilho-Marques, R;
Simou, S;
Moraitis, E;
Wedderburn, LR;
Pullenayegum, E;
Pilkington, CA;
(2018)
Efficacy and Safety of Cyclophosphamide Treatment in Severe Juvenile Dermatomyositis Shown by Marginal Structural Modeling.
Arthritis & Rheumatology
, 70
(5)
pp. 785-793.
10.1002/art.40418.
|
Deakin, CT;
Papadopoulou, C;
McCann, LJ;
Martin, N;
Al-Obaidi, M;
Compeyrot-Lacassagne, S;
Pilkington, CA;
... Juvenile Dermatomyositis Research Group, .; + view all
(2020)
Identification and prediction of novel classes of long-term disease trajectories for patients with juvenile dermatomyositis using growth mixture models.
Rheumatology
10.1093/rheumatology/keaa497.
(In press).
|
Deakin, CT;
Yasin, SA;
Simou, S;
Arnold, KA;
Tansley, SL;
Betteridge, ZE;
McHugh, NJ;
... UK Juvenile Dermatomyositis Research Group, .; + view all
(2016)
Muscle biopsy in combination with myositis-specific autoantibodies aids prediction of outcomes in juvenile dermatomyositis.
Arthritis & Rheumatology
, 68
(11)
pp. 2806-2816.
10.1002/art.39753.
|
Duurland, CL;
Brown, CC;
O'Shaughnessy, RFL;
Wedderburn, LR;
(2017)
CD161(+) Tconv and CD161(+) Treg Share a Transcriptional and Functional Phenotype despite Limited Overlap in TCR beta Repertoire.
Frontiers in Immunology
, 8
, Article 103. 10.3389/fimmu.2017.00103.
|
Duurland, CL;
Wedderburn, LR;
(2014)
Current developments in the use of biomarkers for juvenile idiopathic arthritis.
Current Rheumatology Reports
, 16
, Article 406. 10.1007/s11926-013-0406-3.
|
Edwards, LA;
Nistala, K;
Mills, DC;
Stephenson, HN;
Zilbauer, M;
Wren, BW;
Dorrell, N;
... Bajaj-Elliott, M; + view all
(2010)
Delineation of the Innate and Adaptive T-Cell Immune Outcome in the Human Host in Response to Campylobacter jejuni Infection.
PLOS ONE
, 5
(11)
, Article e15398. 10.1371/journal.pone.0015398.
|
Enders, FB;
Bader-Meunier, B;
Baildam, E;
Constantin, T;
Dolezalova, P;
Feldman, BM;
Lahdenne, P;
... van Royen-Kerkhof, A; + view all
(2017)
Consensus-based recommendations for the management of juvenile dermatomyositis.
Annals of the Rheumatic Diseases
, 76
(2)
pp. 329-340.
10.1136/annrheumdis-2016-209247.
|
Fisher, C;
Ciurtin, C;
Leandro, M;
Sen, D;
Wedderburn, LR;
(2021)
Similarities and Differences Between Juvenile and Adult Spondyloarthropathies.
Frontiers in Medicine
, 8
, Article 681621. 10.3389/fmed.2021.681621.
|
Flood, Chris;
Hirani, Shashivadan P;
Mulligan, Kathleen;
Taylor, Jo;
Harris, Sally;
Wedderburn, Lucy R;
Newman, Stanton P;
(2024)
Economic evaluation of a trial exploring the effects of a web-based support tool for parents of children with juvenile idiopathic arthritis.
Rheumatology
, 63
(SI2)
SI136-SI142.
10.1093/rheumatology/keae188.
|
Gohar, F;
Anink, J;
Moncrieffe, H;
Van Suijlekom-Smit, LWA;
Prince, FHM;
van Rossum, MAJ;
Dolman, KM;
... Holzinger, D; + view all
(2018)
S100A12 Is Associated with Response to Therapy in Juvenile Idiopathic Arthritis.
The Journal of Rheumatology
, 45
(4)
pp. 547-554.
10.3899/jrheum.170438.
|
Gohar, F;
Maschmeyer, P;
Mfarrej, B;
Lemaire, M;
Wedderburn, LR;
Roncarolo, MG;
van Royen-Kerkhof, A;
(2019)
Driving Medical Innovation Through Interdisciplinarity: Unique Opportunities and Challenges.
Frontiers in Medicine
, 6
, Article 35. 10.3389/fmed.2019.00035.
|
Haas, JD;
Nistala, K;
Petermann, F;
Saran, N;
Chennupati, V;
Schmitz, S;
Korn, T;
... Prinz, I; + view all
(2011)
Expression of miRNAs miR-133b and miR-206 in the Il17a/f Locus Is Co-Regulated with IL-17 Production in alpha beta and gamma delta T Cells.
PLOS ONE
, 6
(5)
, Article e20171. 10.1371/journal.pone.0020171.
|
Hanns, L;
Cordingley, L;
Galloway, J;
Norton, S;
Carvalho, LA;
Christie, D;
Sen, D;
... Ioannou, Y; + view all
(2018)
Depressive symptoms, pain and disability for adolescent patients with JIA. Results from the Childhood Arthritis Prospective Study.
Rheumatology
, 57
(8)
pp. 1381-1389.
10.1093/rheumatology/key088.
|
Hawwa, AF;
AlBawab, A;
Rooney, M;
Wedderburn, LR;
Beresford, MW;
McElnay, JC;
(2015)
Methotrexate polyglutamates as a potential marker of adherence to long-term therapy in children with juvenile idiopathic arthritis and juvenile dermatomyositis: an observational, cross-sectional study.
Arthritis Research & Therapy
, 17
, Article 295. 10.1186/s13075-015-0814-z.
|
Hawwa, AF;
AlBawab, A;
Rooney, M;
Wedderburn, LR;
Beresford, MW;
McElnay, JC;
(2014)
A Novel Dried Blood Spot-LCMS Method for the Quantification of Methotrexate Polyglutamates as a Potential Marker for Methotrexate Use in Children.
PLoS ONE
, 9
(2)
, Article e89908. 10.1371/journal.pone.0089908.
|
Hendry, GJ;
Shoop-Worrall, SJ;
Riskowski, JL;
Andrews, P;
Baildam, E;
Chieng, A;
Davidson, J;
... Steultjens, M; + view all
(2018)
Prevalence and course of lower limb disease activity and walking disability over the first 5 years of juvenile idiopathic arthritis: results from the childhood arthritis prospective study.
Rheumatology Advances in Practice
, 2
(2)
10.1093/rap/rky039.
|
Hinks, A;
Bowes, J;
Cobb, J;
Ainsworth, HC;
Marion, MC;
Comeau, ME;
Sudman, M;
... Thomson, W; + view all
(2017)
Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases.
Annals of the Rheumatic Diseases
, 76
(4)
pp. 765-772.
10.1136/annrheumdis-2016-210025.
|
Hinks, A;
Marion, MC;
Cobb, J;
Comeau, ME;
Sudman, M;
Ainsworth, HC;
Bowes, J;
... Prahalad, S; + view all
(2018)
The genetic profile of RF-positive polyarticular juvenile idiopathic arthritis (JIA) resembles adult rheumatoid arthritis (RA).
Arthritis & Rheumatology
, 70
(6)
pp. 957-962.
10.1002/art.40443.
|
Hunter, PJ;
Nistala, K;
Jina, N;
Eddaoudi, A;
Thomson, W;
Hubank, M;
Wedderburn, LR;
(2010)
Biologic Predictors of Extension of Oligoarticular Juvenile Idiopathic Arthritis as Determined From Synovial Fluid Cellular Composition and Gene Expression.
Arthritis and Rheumatism
, 62
(3)
pp. 896-907.
10.1002/art.27284.
|
Hyrich, KL;
Baildam, E;
Pickford, H;
Chieng, A;
Davidson, JE;
Foster, H;
Gardner-Medwin, J;
... Thomson, W; + view all
(2016)
Influence of past breast feeding on pattern and severity of presentation of juvenile idiopathic arthritis.
Archives of Disease in Childhood
, 101
(4)
pp. 348-351.
10.1136/archdischild-2014-308117.
|
Kartawinata, Melissa;
Lin, Wei-Yu;
Jebson, Beth;
O'Brien, Kathryn;
Ralph, Elizabeth;
Welsh, Emma;
Restuadi, Restuadi;
... Wallace, Chris; + view all
(2025)
Identification and validation of interferon-driven gene signature as a predictor of response to methotrexate in juvenile idiopathic arthritis.
Annals of the Rheumatic Diseases
10.1016/j.ard.2025.03.007.
(In press).
|
Kearsley-Fleet, Lianne;
Shaw, Natasha;
Leslie, Jasmine;
Johnson, Michelle;
Wedderburn, Lucy R;
Hyrich, Kimme L;
Humphreys, Jenny H;
(2025)
Mortality rates in children, young people, and young adults with JIA: an observational study using the Clinical Practice Research Datalink (CPRD).
EULAR Rheumatology Open
, 1
(2)
pp. 39-44.
10.1016/j.ero.2025.04.001.
|
Khaosut, P;
Pilkington, C;
Wedderburn, LR;
Compeyrot-Lacassagne, S;
(2019)
An international survey of developing classification criteria for juvenile dermatomyositis-scleroderma overlap.
Rheumatology
, 58
(11)
pp. 2062-2064.
10.1093/rheumatology/kez226.
|
Kolev, M;
West, EE;
Kunz, N;
Chauss, D;
Moseman, EA;
Rahman, J;
Freiwald, T;
... Kemper, C; + view all
(2020)
Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells.
Immunity
, 52
(3)
513-527.e8.
10.1016/j.immuni.2020.02.006.
|
Lawson-Tovey, Saskia;
Smith, Samantha Louise;
Geifman, Nophar;
Shoop-Worrall, Stephanie;
Ng, Sandra;
Barnes, Michael R;
Wedderburn, Lucy R;
... Al-Mossawi, Hussein; + view all
(2023)
The successes and challenges of harmonising juvenile idiopathic arthritis (JIA) datasets to create a large-scale JIA data resource.
Pediatric Rheumatology
, 21
(1)
, Article 70. 10.1186/s12969-023-00839-2.
|
Lilleker, JB;
Vencovsky, J;
Wang, G;
Wedderburn, LR;
Diederichsen, LP;
Schmidt, J;
Oakley, P;
... all EuroMyositis contributors; + view all
(2018)
The EuroMyositis registry: an international collaborative tool to facilitate myositis research.
Annals of the Rheumatic Diseases
, 77
(1)
pp. 30-39.
10.1136/annrheumdis-2017-211868.
|
Lin, Wei-Yu;
Kartawinata, Melissa;
Jebson, Bethany R;
Restuadi, Restuadi;
Peckham, Hannah;
Radziszewska, Anna;
Deakin, Claire;
... Wallace, Chris; + view all
(2025)
Penalised regression improves imputation of cell-type specific expression using RNA-seq data from mixed cell populations compared to domain-specific methods.
PLOS Computational Biology
, 21
(3)
, Article e1012859. 10.1371/journal.pcbi.1012859.
|
Livermore, P;
Gibson, F;
Mulligan, K;
Wedderburn, LR;
McCann, LJ;
Gray, S;
(2021)
Mapping the current psychology provision for children and young people with juvenile dermatomyositis.
Rheumatology Advances in Practice
, 5
(3)
, Article rkab062. 10.1093/rap/rkab062.
|
Livermore, Polly;
Kupiec, Klaudia;
Wedderburn, Lucy R;
Knight, Andrea;
Solebo, Ameenat L;
Shafran, Roz;
Robert, Glenn;
... Gibson, Faith; + view all
(2024)
Designing, developing and testing a chatbot for parents and carers of children and young people with rheumatological conditions (the IMPACT study): Protocol for a co-designed proof of concept study.
JMIR Research Protocols
, 13
, Article e57238. 10.2196/57238.
|
Livermore, P;
Eleftheriou, D;
Wedderburn, LR;
(2016)
The lived experience of juvenile idiopathic arthritis in young people receiving etanercept.
Pediatric Rheumatology
, 14
, Article 21. 10.1186/s12969-016-0083-7.
|
Livermore, P;
Gray, S;
Mulligan, K;
Stinson, JN;
Wedderburn, LR;
Gibson, F;
(2019)
Being on the juvenile dermatomyositis rollercoaster: a qualitative study.
Pediatric Rheumatology
, 17
, Article 30. 10.1186/s12969-019-0332-7.
|
Livermore, P;
Wedderburn, LR;
Gibson, F;
(2019)
You give me a name that I can’t say, but I have to explain what it is every day: the power of poetry to share stories from young people with a rare disease.
Journal of Poetry Therapy
10.1080/08893675.2020.1694210.
(In press).
|
Ll Wilkinson, MG;
Deakin, CT;
Papadopoulou, C;
Eleftheriou, D;
Wedderburn, LR;
(2021)
JAK inhibitors: a potential treatment for JDM in the context of the role of interferon-driven pathology.
Pediatric Rheumatology
, 19
(1)
, Article 146. 10.1186/s12969-021-00637-8.
|
Low, Jie Man;
Hyrich, Kimme L;
Ciurtin, Coziana;
McErlane, Flora;
Wedderburn, Lucy R;
CAPS Principal Investigators, .;
(2023)
The impact of psoriasis on wellbeing and clinical outcomes in juvenile psoriatic arthritis.
Rheumatology
, Article kead370. 10.1093/rheumatology/kead370.
(In press).
|
M F Silva, J;
Ladomenou, F;
Carpenter, B;
Chandra, S;
Sedlacek, P;
Formankova, R;
Grandage, V;
... Veys, P; + view all
(2018)
Allogeneic hematopoietic stem cell transplantation for severe, refractory juvenile idiopathic arthritis.
Blood Adv
, 2
(7)
pp. 777-786.
10.1182/bloodadvances.2017014449.
|
McCann, Liza J;
Livermore, Polly;
Wilkinson, Meredyth G Ll;
Wedderburn, Lucy R;
(2022)
Juvenile dermatomyositis. Where are we now?
Clinical and Experimental Rheumatology
, 40
(2)
pp. 394-403.
|
McCann, LJ;
Arnold, K;
Pilkington, CA;
Huber, AM;
Ravelli, A;
Beard, L;
Beresford, MW;
(2014)
Developing a provisional, international Minimal Dataset for Juvenile Dermatomyositis: for use in clinical practice to inform research.
Pediatr Rheumatol Online J
, 12
, Article 31. 10.1186/1546-0096-12-31.
|
McCann, LJ;
Pilkington, CA;
Huber, AM;
Ravelli, A;
Appelbe, D;
Kirkham, JJ;
Williamson, PR;
... Beresford, MW; + view all
(2017)
Development of a consensus core dataset in juvenile dermatomyositis for clinical use to inform research.
Annals of the Rheumatic Diseases
, 77
(2)
pp. 241-250.
10.1136/annrheumdis-2017-212141.
|
McErlane, F;
Beresford, MW;
Baildam, EM;
Chieng, SE;
Davidson, JE;
Foster, HE;
Gardner-Medwin, J;
... Childhood Arthritis Prospective Study (CAPS); + view all
(2013)
Validity of a three-variable Juvenile Arthritis Disease Activity Score in children with new-onset juvenile idiopathic arthritis.
Annals of the Rheumatic Diseases
, 72
(12)
1983 -1988.
10.1136/annrheumdis-2012-202031.
|
McErlane, F;
Carrasco, R;
Kearsley-Fleet, L;
Baildam, EM;
Wedderburn, LR;
Foster, HE;
Ioannou, Y;
... Hyrich, KL; + view all
(2018)
Growth patterns in early juvenile idiopathic arthritis: Results from the Childhood Arthritis Prospective Study (CAPS).
Seminars in Arthritis and Rheumatism
, 48
(1)
pp. 53-60.
10.1016/j.semarthrit.2017.11.002.
|
McErlane, F;
Foster, HE;
Carrasco, R;
Baildam, EM;
Chieng, SEA;
Davidson, JE;
Ioannou, Y;
... Hyrich, KL; + view all
(2014)
Trends in paediatric rheumatology referral times and disease activity indices over a ten-year period among children and young people with Juvenile Idiopathic Arthritis: results from the childhood arthritis prospective Study.
Rheumatology
, 55
(7)
pp. 1225-1234.
10.1093/rheumatology/kew021.
|
McMorrow, Fionnuala K;
Wedderburn, Lucy R;
Chinoy, Hector;
Oldroyd, Alexander;
Lamb, Janine A;
Rider, Lisa G;
Mammen, Andrew L;
... Tansley, Sarah L; + view all
(2025)
Anti-Sp4 and anti-CCAR1 autoantibodies in UK vs US patients with adult and juvenile-onset anti-TIF1γ-positive myositis.
Rheumatology
, 64
(6)
pp. 3900-3905.
10.1093/rheumatology/keae574.
|
Mellors, J;
Dhaliwal, R;
Longet, S;
Tipton, T;
OCTAVE Consortium;
OPTIC Consortium;
Barnes, E;
... Carroll, M; + view all
(2025)
Complement-mediated enhancement of SARS-CoV-2 antibody neutralisation potency in vaccinated individuals.
Nature Communications
, 16
, Article 2666. 10.1038/s41467-025-57947-8.
|
Mulligan, Kathleen;
Hirani, Shashivadan P;
Harris, Sally;
Taylor, Jo;
Wedderburn, Lucy R;
Newman, Stanton;
(2022)
The Effects of a Web-Based Tool for Parents of Children With Juvenile Idiopathic Arthritis: Randomized Controlled Trial.
Journal of Medical Internet Research
, 24
(5)
, Article e29787. 10.2196/29787.
|
Mulligan, K;
Kassoumeri, L;
Etheridge, A;
Moncrieffe, H;
Wedderburn, LR;
Newman, S;
(2013)
Mothers' reports of the difficulties that their children experience in taking methotrexate for Juvenile Idiopathic Arthritis and how these impact on quality of life.
Pediatric Rheumatology
, 11
, Article 23. 10.1186/1546-0096-11-23.
|
Mulligan, K;
Wedderburn, LR;
Newman, S;
(2015)
The experience of taking methotrexate for juvenile idiopathic arthritis: results of a cross-sectional survey with children and young people.
Pediatric Rheumatology
, 13
(58)
10.1186/s12969-015-0052-6.
|
Naja1, M;
Wedderburn, L;
Ciurtin, C;
(2020)
COVID-19 infection in children and adolescents.
British Journal of Hospital Medicine
pp. 1-10.
10.12968/hmed.2020.0321.
(In press).
|
Ng, KW;
Faulkner, N;
Cornish, GH;
Rosa, A;
Harvey, R;
Hussain, S;
Ulferts, R;
... Kassiotis, G; + view all
(2020)
Preexisting and de novo humoral immunity to SARS-CoV-2 in humans.
Science
, Article eabe1107. 10.1126/science.abe1107.
(In press).
|
Nguyen, Huong D;
Jouen, Fabienne;
Déchelotte, Benoit;
Cordel, Nadège;
Gitiaux, Cyril;
Bodemer, Christine;
Quatier, Pierre;
... UK JDM Cohort and Biomarker study, .; + view all
(2024)
TIF1-gamma IgG2 isotype is not associated with malignancy in juvenile dermatomyositis patients.
Rheumatology
10.1093/rheumatology/keae182.
(In press).
|
Nigrovic, PA;
Colbert, RA;
Holers, VM;
Ozen, S;
Ruperto, N;
Thompson, SD;
Wedderburn, LR;
... Martini, A; + view all
(2021)
Biological classification of childhood arthritis: roadmap to a molecular nomenclature.
Nature Reviews Rheumatology
, 17
pp. 257-269.
10.1038/s41584-021-00590-6.
|
Nistala, K;
Varsani, H;
Wittkowski, H;
Vogl, T;
Krol, P;
Shah, V;
Mamchaoui, K;
... Wedderburn, LR; + view all
(2013)
Myeloid related protein induces muscle derived inflammatory mediators in juvenile dermatomyositis.
Arthritis Research & Therapy
, 15
(5)
, Article R131. 10.1186/ar4311.
|
Nistala, K;
Wedderburn, LR;
(2013)
Update in juvenile myositis.
Curr Opin Rheumatol
, 25
(6)
742 - 746.
10.1097/01.bor.0000434674.62644.02.
|
Ohl, K;
Nickel, H;
Moncrieffe, H;
Klemm, P;
Scheufen, A;
Foell, D;
Wixler, V;
... Tenbrock, K; + view all
(2018)
The transcription factor CREM drives an inflammatory phenotype of T cells in oligoarticular juvenile idiopathic arthritis.
Pediatric Rheumatology
, 16
, Article 39. 10.1186/s12969-018-0253-x.
|
Ombrello, MJ;
Arthur, VL;
Remmers, EF;
Hinks, A;
Tachmazidou, I;
Grom, AA;
Foell, D;
... Thomson, W; + view all
(2017)
Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications.
Annals of the Rheumatic Diseases
, 76
(5)
pp. 906-913.
10.1136/annrheumdis-2016-210324.
|
Omoyinmi, E;
Forabosco, P;
Hamaoui, R;
Bryant, A;
Hinks, A;
Ursu, S;
Childhood Arthritis Prospective Study (CAPS);
... Woo, P; + view all
(2012)
Association of the IL-10 gene family locus on chromosome 1 with juvenile idiopathic arthritis (JIA).
PLOS One
, 7
(10)
, Article e47673. 10.1371/journal.pone.0047673.
|
Omoyinmi, E;
Hamaoui, R;
Pesenacker, A;
Nistala, K;
Moncrieffe, H;
Ursu, S;
Wedderburn, LR;
(2012)
Th1 and Th17 cell subpopulations are enriched in the peripheral blood of patients with systemic juvenile idiopathic arthritis.
Rheumatology
, 51
(10)
1881 -1886.
10.1093/rheumatology/kes162.
|
Papadopoulou, Charalampia;
Chew, Christine;
Wilkinson, Meredyth G Ll;
McCann, Liza;
Wedderburn, Lucy R;
(2023)
Juvenile idiopathic inflammatory myositis: an update on pathophysiology and clinical care.
Nature Reviews Rheumatology
, 19
pp. 343-362.
10.1038/s41584-023-00967-9.
|
Papadopoulou, C;
Hong, Y;
Krol, P;
Al Obaidi, M;
Pilkington, C;
Wedderburn, LR;
Brogan, PA;
(2021)
The Vasculopathy of Juvenile Dermatomyositis: endothelial injury, hypercoagulability, and increased arterial stiffness.
Arthritis Rheumatology
10.1002/art.41639.
(In press).
|
Papadopoulou, C;
Wedderburn, LR;
(2017)
Treatment of Juvenile Dermatomyositis: An Update.
Pediatric Drugs
, 19
(5)
pp. 423-434.
10.1007/s40272-017-0240-6.
|
Parkes, J;
Rothwell, S;
Day, P;
McHugh, NJ;
Betteridge, Z;
Cooper, R;
Ollier, WE;
... Lamb, J; + view all
(2016)
Systematic Protein-Protein Interaction and Pathway Analyses in the Idiopathic Inflammatory Myopathies.
Arthritis Research & Therapy
, 18
, Article 156. 10.1186/s13075-016-1061-7.
|
Parkes, JE;
Rothwell, S;
Oldroyd, A;
Chinoy, H;
Lamb, JA;
Lundberg, IE;
Miller, FW;
... Betteridge, ZE; + view all
(2018)
Genetic background may contribute to the latitude-dependent prevalence of dermatomyositis and anti-TIF1-γ autoantibodies in adult patients with myositis.
Arthritis Research and Therapy
, 20
, Article 117. 10.1186/s13075-018-1617-9.
|
Peckham, Hannah;
Radziszewska, Anna;
Sikora, Justyna;
de Gruijter, Nina M;
Restuadi, Restuadi;
Kartawinata, Melissa;
Martin-Gutierrez, Lucia;
... Ciurtin, Coziana; + view all
(2025)
Estrogen influences class-switched memory B cell frequency only in humans with two X chromosomes.
Journal of Experimental Medicine
, 222
(4)
, Article e20241253. 10.1084/jem.20241253.
|
Peckham, H;
de Gruijter, NM;
Raine, C;
Radziszewska, A;
Ciurtin, C;
Wedderburn, LR;
Rosser, EC;
... Deakin, CT; + view all
(2020)
Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission.
Nature Communications
, 11
, Article 6317. 10.1038/s41467-020-19741-6.
|
Pesenacker, AM;
Wedderburn, LR;
(2013)
T regulatory cells in childhood arthritis - novel insights.
Expert Rev Mol Med
, 15
, Article e13. 10.1017/erm.2013.14.
|
Piper, C;
Pesenacker, AM;
Bending, D;
Thirugnanabalan, B;
Varsani, H;
Wedderburn, LR;
Nistala, K;
(2014)
T cell GM-CSF expression in juvenile arthritis is contingent upon Th17 plasticity.
Arthritis Rheumatol
, 66
(7)
pp. 1955-1960.
10.1002/art.38647.
|
Piper, CJM;
Wilkinson, MGL;
Deakin, CT;
Otto, GW;
Dowle, S;
Duurland, CL;
Adams, S;
... Marques, R; + view all
(2018)
CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α.
Frontiers in Immunology
, 9
, Article 1372. 10.3389/fimmu.2018.01372.
|
Rashid, A;
Cordingley, L;
Carrasco, R;
Foster, HE;
Baildam, EM;
Chieng, A;
Davidson, JE;
... Thomson, W; + view all
(2017)
Patterns of pain over time among children with juvenile idiopathic arthritis.
Archives of Disease in Childhood
10.1136/archdischild-2017-313337.
|
|
Ravelli, Angelo;
Rosina, Silvia;
MacMahon, Jayne M;
Baird, Talia;
Rebollo-Giménez, Ana Isabel;
Hinze, Claas;
McCann, Liza J;
... Feldman, Brian M; + view all
(2025)
Treating juvenile dermatomyositis to target: Paediatric Rheumatology European Society/Childhood Arthritis and Rheumatology Research Alliance-endorsed recommendations from an international task force.
Annals of the Rheumatic Diseases
10.1016/j.ard.2025.04.024.
(In press).
|
Rietveld, A;
Wienke, J;
Visser, E;
Vree Egberts, W;
Schlumberger, W;
van Engelen, B;
van Royen-Kerkhof, A;
... Juvenile Dermatomyositis Research Group; + view all
(2021)
Anti‐cN‐1A autoantibodies are absent in juvenile dermatomyositis.
Arthritis & Rheumatology
, 73
(7)
pp. 1329-1333.
10.1002/art.41660.
|
Rosser, EC;
Lom, H;
Bending, D;
Duurland, CL;
Bajaj-Elliott, M;
Wedderburn, LR;
(2018)
Brief Report: Innate lymphoid cells and T-cells contribute to the IL-17A signature detected in the synovial fluid of patients with Juvenile Idiopathic Arthritis.
Arthritis and Rheumatology
10.1002/art.40731.
(In press).
|
Rosser, EC;
Piper, CJM;
Matei, DE;
Blair, PA;
Rendeiro, AF;
Orford, M;
Alber, DG;
... Mauri, C; + view all
(2020)
Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells.
Cell Metabolism
10.1016/j.cmet.2020.03.003.
(In press).
|
Rothwell, Simon;
Amos, Christopher I;
Miller, Frederick W;
Rider, Lisa G;
Lundberg, Ingrid E;
Gregersen, Peter K;
Vencovsky, Jiri;
... Myositis Genetics Consortium, .; + view all
(2023)
Identification of Novel Associations and Localization of Signals in Idiopathic Inflammatory Myopathies Using Genome-Wide Imputation.
Arthritis & Rheumatology
10.1002/art.42434.
(In press).
|
Rothwell, S;
Chinoy, H;
Lamb, JA;
Miller, FW;
Rider, LG;
Wedderburn, LR;
McHugh, NJ;
... Myositis Genetics Consortium (MYOGEN), .; + view all
(2019)
Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups.
Annals of the Rheumatic Diseases
, 78
pp. 996-1002.
10.1136/annrheumdis-2019-215046.
|
Shoop-Worrall, SJ;
Verstappen, SM;
McDonagh, JE;
Baildam, E;
Chieng, A;
Davidson, J;
Foster, H;
... Hyrich, KL; + view all
(2018)
Long‐Term Outcomes Following Achievement of Clinically Inactive Disease in Juvenile Idiopathic Arthritis.
Arthritis & Rheumatology
, 70
(9)
pp. 1519-1529.
10.1002/art.40519.
|
Shoop-Worrall, SJW;
Hyrich, KL;
Verstappen, SM;
Sergeant, JC;
Baildam, E;
Chieng, A;
Davidson, J;
... McDonagh, JE; + view all
(2020)
Comparing Proxy, Adolescent and Adult Assessments of Functional Ability in Adolescents with Juvenile Idiopathic Arthritis.
Arthritis Care and Research
, 72
(4)
pp. 517-524.
10.1002/acr.23877.
|
Shoop-Worrall, SJW;
Hyrich, KL;
Wedderburn, LR;
Thomson, W;
Geifman, N;
Baildam, E;
Barnes, M;
... Yarwood, A; + view all
(2020)
Patient-reported wellbeing and clinical disease measures over time captured by multivariate trajectories of disease activity in individuals with juvenile idiopathic arthritis in the UK: a multicentre prospective longitudinal study.
The Lancet Rheumatology
10.1016/s2665-9913(20)30269-1.
(In press).
|
Shoop-Worrall, SJW;
Verstappen, SMM;
Baildam, E;
Chieng, A;
Davidson, J;
Foster, H;
Ioannou, Y;
... Hyrich, KL; + view all
(2017)
How common is clinically inactive disease in a prospective cohort of patients with juvenile idiopathic arthritis? The importance of definition.
Annals of the Rheumatic Diseases
, 76
(8)
pp. 1381-1388.
10.1136/annrheumdis-2016-210511.
|
Shoop-Worrall, SJW;
Wu, Q;
Davies, R;
Hyrich, KL;
Wedderburn, LR;
(2019)
Predicting disease outcomes in juvenile idiopathic arthritis: challenges, evidence, and new directions.
The Lancet Child & Adolescent Health
, 3
(10)
pp. 725-733.
10.1016/S2352-4642(19)30188-9.
|
Soponkanaporn, S;
Deakin, CT;
Schutz, PW;
Marshall, LR;
Yasin, SA;
Johnson, CM;
Sag, E;
... Jacques, TS; + view all
(2019)
Expression of myxovirus‐resistance protein A: a possible marker of muscle disease activity and autoantibody specificities in juvenile dermatomyositis.
Neuropathology and Applied Neurobiology
, 45
(4)
pp. 410-420.
10.1111/nan.12498.
|
Syntakas, AE;
Kartawinata, M;
Evans, NML;
Nguyen, HD;
Papadopoulou, C;
Al Obaidi, M;
Pilkington, C;
... The JDCBS; + view all
(2025)
Spatial transcriptomic analysis of muscle biopsy from patients with treatment-naive juvenile dermatomyositis reveals mitochondrial abnormalities despite disease-related interferon-driven signature.
Annals of the Rheumatic Diseases
10.1016/j.ard.2025.07.015.
(In press).
|
Tansley, SL;
Betteridge, ZE;
Gunawardena, H;
Jacques, TS;
Owens, CM;
Pilkington, C;
Arnold, K;
... McHugh, NJ; + view all
(2014)
Anti-MDA5 autoantibodies in juvenile dermatomyositis identify a distinct clinical phenotype: a prospective cohort study.
Arthritis Res Ther
, 16
(4)
, Article R138. 10.1186/ar4600.
|
Tansley, SL;
Betteridge, ZE;
Shaddick, G;
Gunawardena, H;
Arnold, K;
Wedderburn, LR;
McHugh, NJ;
(2014)
Calcinosis in juvenile dermatomyositis is influenced by both anti-NXP2 autoantibody status and age at disease onset.
Rheumatology (Oxford)
, 53
(12)
pp. 2204-2208.
10.1093/rheumatology/keu259.
|
Tansley, SL;
Betteridge, ZE;
Simou, S;
Jacques, TS;
Pilkington, C;
Wood, M;
Warrier, K;
... Juvenile Dermatomyositis Research Group; + view all
(2017)
Anti-HMGCR Autoantibodies in Juvenile Idiopathic Inflammatory Myopathies Identify a Rare but Clinically Important Subset of Patients.
The Journal of Rheumatology
, 44
(4)
pp. 488-492.
10.3899/jrheum.160871.
|
Tansley, SL;
Simou, S;
Shaddick, G;
Betteridge, ZE;
Almeida, B;
Gunawardena, H;
Thomson, W;
... McHugh, NJ; + view all
(2017)
Autoantibodies in juvenile-onset myositis: Their diagnostic value and associated clinical phenotype in a large UK cohort.
J Autoimmun
10.1016/j.jaut.2017.06.007.
(In press).
|
Thompson, KN;
Bonham, KS;
Ilott, NE;
Britton, GJ;
Colmenero, P;
Bullers, SJ;
McIver, LJ;
... Huttenhower, C; + view all
(2023)
Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes.
Science translational medicine
, 15
(706)
, Article eabn4722. 10.1126/scitranslmed.abn4722.
|
Tordoff, Melissa;
Smith, Samantha L;
Lawson-Tovey, Saskia;
Dick, Andrew D;
Beresford, Michael W;
Ramanan, Athimalaipet V;
Hyrich, Kimme L;
... LUSTER Consortium, .; + view all
(2024)
Integration of Genetic and Clinical Risk Factors for Risk Classification of Uveitis in Patients With Juvenile Idiopathic Arthritis.
Arthritis & Rheumatology
, 76
(12)
pp. 1789-1796.
10.1002/art.42955.
|
Turro, E;
Astle, WJ;
Megy, K;
Gräf, S;
Greene, D;
Shamardina, O;
Allen, HL;
... Ouwehand, WH; + view all
(2020)
Whole-genome sequencing of patients with rare diseases in a national health system.
Nature
, 583
pp. 96-102.
10.1038/s41586-020-2434-2.
|
van Dijkhuizen, EHP;
De Iorio, M;
Wedderburn, LR;
Deakin, CT;
JDRG;
(2018)
Clinical signs and symptoms in a joint model of four disease activity parameters in juvenile dermatomyositis: a prospective, longitudinal, multicenter cohort study.
Arthritis Research & Therapy
, 20
(1)
, Article 180. 10.1186/s13075-018-1687-8.
|
van Dijkhuizen, EP;
Deakin, CT;
Wedderburn, LR;
De Iorio, M;
(2017)
Modelling disease activity in juvenile dermatomyositis: A Bayesian approach.
Statistical Methods in Medical Research
10.1177/0962280217713233.
(In press).
|
Varnier, GC;
Pilkington, CA;
Wedderburn, LR;
(2018)
Juvenile dermatomyositis: novel treatment approaches and outcomes.
Current Opinion in Rheumatology
, 30
(6)
pp. 650-654.
10.1097/BOR.0000000000000538.
|
Varsani, H;
Charman, SC;
Li, CK;
Marie, SKN;
Amato, AA;
Banwell, B;
Bove, KE;
... Wedderburn, LR; + view all
(2015)
Validation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease.
Annals of the Rheumatic Diseases
, 74
(1)
pp. 204-210.
10.1136/annrheumdis-2013-203396.
|
Webb, K;
Wedderburn, LR;
(2015)
Advances in the treatment of polyarticular juvenile idiopathic arthritis.
Current Opinion in Rheumatology
, 27
(5)
pp. 505-510.
10.1097/BOR.0000000000000206.
|
Wedderburn, Lucy R;
Ramanan, Athimalaipet V;
Croft, Adam P;
Hyrich, Kimme L;
Dick, Andrew;
(2022)
Towards molecular-pathology informed clinical trials in childhood arthritis to achieve precision medicine in juvenile idiopathic arthritis.
Annals of the Rheumatic Diseases
10.1136/ard-2022-222553.
(In press).
|
Wedderburn, LR;
Webb, K;
Peckham, H;
Radziszewska, A;
Menon, M;
Oliveri, P;
Simpson, F;
... Ioannou, Y; + view all
(2019)
Sex and Pubertal Differences in the Type 1 Interferon Pathway Associate With Both X Chromosome Number and Serum Sex Hormone Concentration.
Frontiers in Immunology
, 9
, Article 3167. 10.3389/fimmu.2018.03167.
|
Wei, W;
Tuna, S;
Keogh, MJ;
Smith, KR;
Aitman, TJ;
Beales, PL;
Bennett, DL;
... Chinnery, PF; + view all
(2019)
Germline selection shapes human mitochondrial DNA diversity.
Science
, 364
(6442)
, Article eaau6520. 10.1126/science.aau6520.
|
Wickwar, S;
Buerkle, K;
McBain, H;
Ciciriello, S;
Osborne, RH;
Wedderburn, LR;
Newman, SP;
(2013)
Adaptation of the methotrexate in rheumatoid arthritis knowledge questionnaire (MiRAK) for use with parents of children with juvenile idiopathic arthritis: a qualitative study.
Pediatric Rheumatology
, 11
, Article 27. 10.1186/1546-0096-11-27.
|
Wienke, J;
Bellutti Enders, F;
Lim, J;
Mertens, JS;
van den Hoogen, LL;
Wijngaarde, CA;
Yeo, JG;
... van Wijk, F; + view all
(2019)
Galectin-9 and CXCL10 as biomarkers for disease activity in juvenile dermatomyositis: a longitudinal cohort study and multi-cohort validation.
Arthritis and Rheumatology
, 71
(8)
pp. 1377-1390.
10.1002/art.40881.
|
Wienke, J;
Deakin, CT;
Wedderburn, LR;
van Wijk, F;
van Royen-Kerkhof, A;
(2018)
Systemic and Tissue Inflammation in Juvenile Dermatomyositis: From Pathogenesis to the Quest for Monitoring Tools.
Frontiers in Immunology
, 9
, Article 2951. 10.3389/fimmu.2018.02951.
|
Wilkinson, Meredyth G Ll;
Moulding, Dale;
McDonnell, Thomas CR;
Orford, Michael;
Wincup, Chris;
Ting, Joanna YJ;
Otto, Georg W;
... Wedderburn, Lucy R; + view all
(2022)
Role of CD14+ monocyte-derived oxidised mitochondrial DNA in the inflammatory interferon type 1 signature in juvenile dermatomyositis.
Annals of the Rheumatic Diseases
10.1136/ard-2022-223469.
(In press).
|
Wilkinson, MGL;
Wu, W;
O’Brien, K;
Deakin, CT;
Wedderburn, LR;
Livermore, P;
(2021)
A survey to understand the feelings towards and impact of COVID-19 on the households of juvenile dermato myositis patients from a parent or carer perspective.
Rheumatology Advances in Practice
, 5
(3)
, Article rkab058. 10.1093/rap/rkab058.
|
Wu, Q;
Chaplin, H;
Ambrose, N;
Sen, D;
Leandro, MJ;
Wing, C;
Daly, N;
... Ioannou, Y; + view all
(2016)
Juvenile arthritis disease activity score is a better reflector of active disease than the disease activity score 28 in adults with polyarticular juvenile idiopathic arthritis.
Annals of the Rheumatic Diseases
, 75
(3)
pp. 635-636.
10.1136/annrheumdis-2015-208462.
|
Wu, Q;
Pesenacker, AM;
Stansfield, A;
King, D;
Barge, D;
Foster, HE;
Abinun, M;
(2014)
Immunological characteristics and T cell receptor clonal diversity in children with systemic juvenile idiopathic arthritis undergoing T cell depleted autologous stem cell transplantation.
Immunology
, 142
(2)
pp. 227-236.
10.1111/imm.12245.
|
Wu, Q;
Wedderburn, LR;
McCann, LJ;
(2018)
Juvenile dermatomyositis: Latest advances.
Best Practice & Research: Clinical Rheumatology
, 31
(4)
pp. 535-557.
10.1016/j.berh.2017.12.003.
|
Yarwood, Annie;
Shoop-Worrall, Stephanie;
López-Isac, Elena;
Smith, Samantha Louise;
Morris, Andrew P;
Baildam, Eileen;
Chieng, Alice;
... Eyre, Stephen; + view all
(2022)
No evidence that genetic predictors of susceptibility predict changes in core outcomes in JIA.
Rheumatology
, 61
(10)
pp. 4136-4144.
10.1093/rheumatology/keab942.
|
Yasin, SA;
Schutz, PW;
Deakin, CT;
Sag, E;
Varsani, H;
Simou, S;
Marshall, LR;
... UK Juvenile Dermatomyositis Research Group (UK-Ireland); + view all
(2019)
Histological heterogeneity in a large clinical cohort of juvenile idiopathic inflammatory myopathy: analysis by myositis autoantibody and pathological features.
Neuropathology and Applied Neurobiology
, 45
(5)
pp. 495-512.
10.1111/nan.12528.
|
Yeung, RS;
Albani, S;
Feldman, BM;
Mellins, E;
Prakken, B;
Wedderburn, LR;
(2016)
Enhancing translational research in paediatric rheumatology through standardization.
Nature Reviews Rheumatology
, 12
(11)
pp. 684-690.
10.1038/nrrheum.2016.156.
|
|
Zhu, Catherine;
Han, Younghun;
Byun, Jinyoung;
Xiao, Xiangjun;
Rothwell, Simon;
Miller, Frederick W;
Lundberg, Ingrid E;
... Myositis Genetics Consortium, (MYOGEN); + view all
(2025)
Meta-analyses uncover the genetic architecture of Idiopathic Inflammatory Myopathies.
Arthritis & Rheumatology
, 77
(6)
750 -764.
10.1002/art.43088.
|
Working / discussion paper
Wedderburn, L;
Peckham, H;
De Gruijter, N;
Raine, C;
Radziszewska, A;
Ciurtin, C;
Rosser, E;
... Webb, K; + view all
(2020)
Sex-bias in COVID-19: a meta-analysis and review of sex differences in disease and immunity.
Research Square: Durham, NC, USA.
|
Conference item
Shoop-Worrall, S;
Hyrich, K;
Wedderburn, L;
Geifmanon, N;
(2022)
DISTINCT CLUSTERS OF JIA AT METHOTREXATE INITIATION IDENTIFIED USING TOPOLOGICAL DATA ANALYSIS.
Presented at: EULAR 2022 European Congress of Rheumatology, Copenhagen, Denmark.
|
Webb, K;
Butler, G;
Ciurtin, C;
Peckham, H;
Radziszewska, A;
Wedderburn, L;
Ioannou, J;
(2018)
Pubertal females produce an enhanced interferon-alpha anti-viral response compared to males, which is associated with X chromosome number, and not sex hormones.
Presented at: 57th European Society of Paediatric Endocrinology Congress (ESPE), Athens, Greece.
|
Webb, K;
Butler, G;
Ciurtin, C;
Peckham, H;
Radziszewska, A;
Wedderburn, L;
Ioannou, J;
(2018)
Sex Differences in Autoimmune Disease: Testosterone is Associated with a Decrease in Expression of Key Anti-viral Genes During Puberty, Which may Decrease the Risk of Autoimmunity in Males.
Presented at: 57th European Society of Paediatric Endocrinology Congress (ESPE), Athens, Greece.
|
Webb, K;
Butler, G;
Ciurtin, C;
Peckham, H;
Radziszewska, A;
Wedderburn, L;
Ioannou, Y;
(2018)
Juvenile systemic lupus erythematosus with a baseline high interferon signature associates with increased immune cell TLR7 expression and enhanced TLR7 dependent IFNα production.
Presented at: 57th European Society of Paediatric Endocrinology Congress (ESPE), Athens, Greece.
|
Thesis
Lom, Hannah RG;
(2017)
Defining the T cell and innate lymphoid cell signature in childhood arthritis.
Doctoral thesis , UCL (University College London).
|