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Number of items: 203.

Article

Abbasizanjani, H; Torabi, F; Bedston, S; Bolton, T; Davies, G; Denaxas, S; Griffiths, R; ... Akbari, A; + view all (2023) Harmonising electronic health records for reproducible research: challenges, solutions and recommendations from a UK-wide COVID-19 research collaboration. BMC Medical Informatics and Decision Making , 23 (1) , Article 8. 10.1186/s12911-022-02093-0. (In press). Green open access
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Aldridge, RW; Menezes, D; Lewer, D; Cornes, M; Evans, H; Blackburn, RM; Byng, R; ... Hayward, A; + view all (2019) Causes of death among homeless people: a population-based cross-sectional study of linked hospitalisation and mortality data in England. Wellcome Open Research , 4 , Article 49. 10.12688/wellcomeopenres.15151.1. Green open access
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Alexander, N; Alexander, DC; Barkhof, F; Denaxas, S; (2021) Identifying and evaluating clinical subtypes of Alzheimer's disease in care electronic health records using unsupervised machine learning. BMC Medical Informatics and Decision Making , 21 , Article 343. 10.1186/s12911-021-01693-6. Green open access
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Alexander, N; Alexander, DC; Barkhof, F; Denaxas, S; (2020) Using Unsupervised Learning to Identify Clinical Subtypes of Alzheimer's Disease in Electronic Health Records. Studies in Health Technology and Informatics , 270 pp. 499-503. 10.3233/SHTI200210. Green open access
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Ali, Nabila MH; Chawner, Samuel JRA; Kushan-Wells, Leila; Bearden, Carrie E; Mulle, Jennifer Gladys; Pollak, Rebecca M; Gur, Raquel E; ... Van den Bree, Marianne BM; + view all (2025) Comparison of autism domains across thirty rare variant genotypes. eBioMedicine , 112 , Article 105521. 10.1016/j.ebiom.2024.105521. Green open access
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Allan, V; Banerjee, A; Shah, AD; Patel, R; Denaxas, S; Casas, JP; Hemingway, H; (2016) Net clinical benefit of warfarin in individuals with atrial fibrillation across stroke risk and across primary and secondary care. Heart , 103 (3) pp. 210-218. 10.1136/heartjnl-2016-309910. Green open access
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Archangelidi, O; Pujades-Rodriguez, M; Timmis, A; Jouven, X; Denaxas, S; Hemingway, H; (2018) Clinically recorded heart rate and incidence of 12 coronary, cardiac, cerebrovascular and peripheral arterial diseases in 233,970 men and women: A linked electronic health record study. European Journal of Preventive Cardiology , 25 (14) pp. 1485-1495. 10.1177/2047487318785228. Green open access
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Austin-Zimmerman, I; Wronska, M; Wang, B; Irizar, H; Thygesen, JH; Bhat, A; Denaxas, S; ... Bramon, E; + view all (2021) The influence of CYP2D6 and CYP2C19 genetic variation on diabetes mellitus risk in people taking antidepressants and antipsychotics. Genes , 12 (11) , Article 1758. 10.3390/genes12111758. Green open access
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Banerjee, A; Pasea, L; Chung, S-C; Direk, K; Asselbergs, F; Grobbee, DE; Kotecha, D; ... Hemingway, H; + view all (2022) A population-based study of 92 clinically recognised risk factors for heart failure: co-occurrence, prognosis and preventive potential. European Journal of Hearth Failure , 24 (3) pp. 466-480. 10.1002/ejhf.2417. Green open access
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Banerjee, A; Pasea, L; Manohar, S; Lai, AG; Hemingway, E; Sofer, I; Katsoulis, M; ... and members of the Health Data Research UK COVID-19 Patient and; + view all (2021) 'What is the risk to me from COVID-19?': Public involvement in providing mortality risk information for people with 'high-risk' conditions for COVID-19 (OurRisk.CoV). Clinical Medicine Journal , 21 (6) e620-e628. 10.7861/clinmed.2021-0386. Green open access
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Banerjee, Amitava; Dashtban, Ashkan; Chen, Suliang; Pasea, Laura; Thygesen, Johan H; Fatemifar, Ghazaleh; Tyl, Benoit; ... Hemingway, Harry; + view all (2023) Identifying subtypes of heart failure from three electronic health record sources with machine learning: an external, prognostic, and genetic validation study. The Lancet Digital Health , 5 (6) e370-e379. 10.1016/S2589-7500(23)00065-1. Green open access
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Banerjee, A; Allan, V; Denaxas, S; Shah, A; Kotecha, D; Lambiase, PD; Jacob, J; ... Hemingway, H; + view all (2019) Subtypes of atrial fibrillation with concomitant valvular heart disease derived from electronic health records: phenotypes, population prevalence, trends and prognosis. EP Europace 10.1093/europace/euz220. (In press). Green open access
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Banerjee, A; Chen, S; Fatemifar, G; Zeina, M; Lumbers, RT; Mielke, J; Gill, S; ... Hemingway, H; + view all (2021) Machine learning for subtype definition and risk prediction in heart failure, acute coronary syndromes and atrial fibrillation: systematic review of validity and clinical utility. BMC Medicine , 19 (1) , Article 85. 10.1186/s12916-021-01940-7. Green open access
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Banerjee, A; Chen, S; Pasea, L; Lai, AG; Katsoulis, M; Denaxas, S; Nafilyan, V; ... Hemingway, H; + view all (2021) Excess deaths in people with cardiovascular diseases during the COVID-19 pandemic. European Journal of Preventive Cardiology 10.1093/eurjpc/zwaa155. (In press). Green open access
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Banerjee, A; Katsoulis, M; Lai, AG; Pasea, L; Treibel, TA; Manisty, C; Denaxas, S; ... Moon, JC; + view all (2020) Clinical academic research in the time of Corona: A simulation study in England and a call for action. PLoS One , 15 (8) , Article e0237298. 10.1371/journal.pone.0237298. Green open access
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Banerjee, A; Pasea, L; Harris, S; Gonzalez-Izquierdo, A; Torralbo, A; Shallcross, L; Noursadeghi, M; ... Hemingway, H; + view all (2020) Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study. The Lancet 10.1016/S0140-6736(20)30854-0. (In press). Green open access
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Barreto, ML; Ichihara, MY; Almeida, BA; Barreto, ME; Cabral, L; Fiaccone, RL; Carreiro, RP; ... Smeeth, L; + view all (2019) The centre for data and knowledge integration for health (CIDACS): Linking health and social data in Brazil. International Journal of Population Data Science , 4 (2) 10.23889/ijpds.v4i2.1140. Green open access
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Barrett, JE; Cakiroglu, A; Bunce, C; Shah, A; Denaxas, S; (2020) Selective recruitment designs for improving observational studies using electronic health records. Statistics in Medicine 10.1002/sim.8556. (In press). Green open access
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Bell, S; Daskalopoulou, M; Rapsomaniki, E; George, J; Britton, A; Bobak, M; Casas, JP; ... Hemingway, H; + view all (2017) Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: population based cohort study using linked health records. the BMJ , 356 , Article j909. 10.1136/bmj.j909. Green open access
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Bidulka, P; Scott, J; Taylor, DM; Udayaraj, U; Caskey, F; Teece, L; Sweeting, M; ... Nitsch, D; + view all (2022) Impact of chronic kidney disease on case ascertainment for hospitalised acute myocardial infarction: an English cohort study. BMJ Open , 12 (3) , Article e057909. 10.1136/bmjopen-2021-057909. Green open access
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Blackburn, RM; Hayward, A; Cornes, M; McKee, M; Lewer, D; Whiteford, M; Menezes, D; ... Aldridge, RW; + view all (2017) Outcomes of specialist discharge coordination and intermediate care schemes for patients who are homeless: analysis protocol for a population-based historical cohort. BMJ Open , 7 (12) , Article e019282. 10.1136/bmjopen-2017-019282. Green open access
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Blackshaw, H; Vennik, J; Philpott, C; Thomas, M; Eyles, C; Carpenter, J; Clarke, CS; ... Hopkins, C; + view all (2019) Expert panel process to optimise the design of a randomised controlled trial in chronic rhinosinusitis (the MACRO programme). Trials , 20 , Article 230. 10.1186/s13063-019-3318-3. Green open access
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Boratto, M; Alonso, P; Pinto, C; Melo, P; Barreto, M; Denaxas, S; (2018) Exploring hybrid parallel systems for probabilistic record linkage. The Journal of Supercomputing 10.1007/s11227-018-2328-3. (In press). Green open access
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Brakenhoff, TB; Franks, B; Goodale, BM; Van de Wijgert, J; Montes, S; Veen, D; Fredslund, EK; ... COVID-RED Consortium; + view all (2021) A prospective, randomized, single-blinded, crossover trial to investigate the effect of a wearable device in addition to a daily symptom diary for the Remote Early Detection of SARS-CoV-2 infections (COVID-RED): a structured summary of a study protocol for a randomized controlled trial. Trials , 22 , Article 694. 10.1186/s13063-021-05643-5. Green open access
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Brakenhoff, TB; Franks, B; Goodale, BM; van de Wijgert, J; Montes, S; Veen, D; Fredslund, EK; ... COVID-RED Consortium; + view all (2021) A prospective, randomized, single-blinded, crossover trial to investigate the effect of a wearable device in addition to a daily symptom diary for the remote early detection of SARS-CoV-2 infections (COVID-RED): a structured summary of a study protocol for a randomized controlled trial. Trials , 22 , Article 412. 10.1186/s13063-021-05241-5. Green open access
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Brauer, R; Smeeth, L; Anaya-Izquierdo, K; Timmis, A; Denaxas, SC; Farrington, CP; Whitaker, H; ... Douglas, I; + view all (2015) Antipsychotic drugs and risks of myocardial infarction: a self-controlled case series study. European Heart Journal , 36 (16) pp. 984-992. 10.1093/eurheartj/ehu263. Green open access
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Bromage, DI; Godec, TR; Pujades-Rodriguez, M; Gonzalez-Izquierdo, A; Denaxas, S; Hemingway, H; Yellon, DM; (2019) Metformin use and cardiovascular outcomes after acute myocardial infarction in patients with type 2 diabetes: a cohort study. Cardiovascular Diabetology , 18 , Article 168. 10.1186/s12933-019-0972-4. Green open access
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Castro-de-Araujo, Luis Fernando Silva; Cortes, Fanny; de Siqueira Filha, Noêmia Teixeira; Rodrigues, Elisângela da Silva; Machado, Daiane Borges; de Araujo, Jacyra Azevedo Paiva; Lewis, Glyn; ... Barreto, Mauricio L; + view all (2022) Patterns of multimorbidity and some psychiatric disorders: A systematic review of the literature. Frontiers in Psychology , 13 , Article 940978. 10.3389/fpsyg.2022.940978. Green open access
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Chahal, C Anwar A; Alahdab, Fares; Asatryan, Babken; Addison, Daniel; Aung, Nay; Chung, Mina K; Denaxas, Spiros; ... Armoundas, Antonis A; + view all (2025) Data Interoperability and Harmonization in Cardiovascular Genomic and Precision Medicine. Circulation: Genomic and Precision Medicine , 18 (3) , Article e004624. 10.1161/CIRCGEN.124.004624. Green open access
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Chapman, M; Mumtaz, S; Rasmussen, LV; Karwath, A; Gkoutos, GV; Gao, C; Thayer, D; ... Curcin, V; + view all (2021) Desiderata for the development of next-generation electronic health record phenotype libraries. GigaScience , 10 (9) , Article giab059. 10.1093/gigascience/giab059. Green open access
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Chawner, SJRA; Doherty, JL; Anney, RJL; Antshel, KM; Bearden, CE; Bernier, R; Chung, WK; ... van den Bree, MBM; + view all (2021) A Genetics-First Approach to Dissecting the Heterogeneity of Autism: Phenotypic Comparison of Autism Risk Copy Number Variants. The American Journal of Psychiatry , 178 (1) pp. 77-86. 10.1176/appi.ajp.2020.20010015. Green open access
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Chung, Sheng-Chia; Providencia, Rui; Sofat, Reecha; Pujades-Rodriguez, Mar; Torralbo, Ana; Fatemifar, Ghazaleh; Fitzpatrick, Natalie K; ... Denaxas, Spiros; + view all (2022) Incidence, morbidity, mortality and disparities in dementia: A population linked electronic health records study of 4.3 million individuals. Alzheimer's & Dementia 10.1002/alz.12635. (In press). Green open access
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Chung, S-C; Pujades-Rodriguez, M; Duyx, B; Denaxas, SC; Pasea, L; Hingorani, A; Timmis, A; ... Hemingway, H; + view all (2018) Time spent at blood pressure target and the risk of death and cardiovascular diseases. PLoS One , 13 (9) , Article e0202359. 10.1371/journal.pone.0202359. Green open access
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Clarke, Caroline S; Williamson, Elizabeth; Denaxas, Spiros; Carpenter, James R; Thomas, Mike; Blackshaw, Helen; Schilder, Anne GM; ... MACRO programme team; + view all (2022) Observational retrospective study calculating health service costs of patients receiving surgery for chronic rhinosinusitis in England, using linked patient-level primary and secondary care electronic data. BMJ Open , 12 (2) , Article e055603. 10.1136/bmjopen-2021-055603. Green open access
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Cleary, F; Kim, L; Prieto-Merino, D; Wheeler, D; Steenkamp, R; Fluck, R; Adlam, D; ... Nitsch, D; + view all (2022) Association between practice coding of chronic kidney disease (CKD) in primary care and subsequent hospitalisations and death: a cohort analysis using national audit data. BMJ open , 12 (10) , Article e064513. 10.1136/bmjopen-2022-064513. Green open access
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Collins, Gary S; Moons, Karel GM; Dhiman, Paula; Riley, Richard D; Beam, Andrew L; Van Calster, Ben; Ghassemi, Marzyeh; ... Logullo, Patricia; + view all (2024) TRIPOD+AI statement: updated guidance for reporting clinical prediction models that use regression or machine learning methods. BMJ , 385 , Article e078378. 10.1136/bmj-2023-078378. Green open access
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Dashtban, Ashkan; Mizani, Mehrdad A; Pasea, Laura; Denaxas, Spiros; Corbett, Richard; Mamza, Jil B; Gao, He; ... Banerjee, Amitava; + view all (2023) Identifying subtypes of chronic kidney disease with machine learning: development, internal validation and prognostic validation using linked electronic health records in 350,067 individuals. EBioMedicine , 89 , Article 104489. 10.1016/j.ebiom.2023.104489. Green open access
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Daskalopoulou, M; George, J; Walters, K; Osborn, DP; Batty, GD; Stogiannis, D; Rapsomaniki, E; ... Hemingway, H; + view all (2016) Depression as a Risk Factor for the Initial Presentation of Twelve Cardiac, Cerebrovascular, and Peripheral Arterial Diseases: Data Linkage Study of 1.9 Million Women and Men. PLOS One , 11 (4) , Article e0153838. 10.1371/journal.pone.0153838. Green open access
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Denaxas, S; Direk, K; Gonzalez-Izquierdo, A; Pikoula, M; Cakiroglu, A; Moore, J; Hemingway, H; (2017) Methods for enhancing the reproducibility of biomedical research findings using electronic health records. BioData Mining , 10 , Article 31. 10.1186/s13040-017-0151-7. Green open access
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Denaxas, S; Gonzalez-Izquierdo, A; Direk, K; Fitzpatrick, NK; Fatemifar, G; Banerjee, A; Dobson, RJB; ... Hemingway, H; + view all (2019) UK phenomics platform for developing and validating electronic health record phenotypes: CALIBER. Journal of the American Medical Informatics Association , 26 (12) pp. 1545-1559. 10.1093/jamia/ocz105. (In press). Green open access
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Denaxas, S; Shah, AD; Mateen, BA; Kuan, V; Quint, JK; Fitzpatrick, N; Torralbo, A; ... Hemingway, H; + view all (2020) A semi-supervised approach for rapidly creating clinical biomarker phenotypes in the UK Biobank using different primary care EHR and clinical terminology systems. JAMIA Open , Article ooaa047. 10.1093/jamiaopen/ooaa047. Green open access
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Denaxas, SC; Asselbergs, FW; Moore, JH; (2016) The tip of the iceberg: challenges of accessing hospital electronic health record data for biological data mining. BioData Mining , 9 , Article 29. 10.1186/s13040-016-0109-1. Green open access
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Denaxas, SC; George, J; Herrett, E; Shah, AD; Kalra, D; Hingorani, AD; Kivimaki, M; ... Hemingway, H; + view all (2012) Data Resource Profile: Cardiovascular disease research using linked bespoke studies and electronic health records (CALIBER). International Journal of Epidemiology , 41 (6) pp. 1625-1638. 10.1093/ije/dys188. Gold open access
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Dennis, JM; Mateen, BA; Sonabend, R; Thomas, NJ; Patel, KA; Hattersley, AT; Denaxas, S; ... Vollmer, SJ; + view all (2020) Type 2 Diabetes and COVID-19–Related Mortality in the Critical Care Setting: A National Cohort Study in England, March–July 2020. Diabetes Care 10.2337/dc20-1444. (In press). Green open access
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Dickerman, BA; García-Albéniz, X; Logan, RW; Denaxas, S; Hernán, MA; (2020) Emulating a target trial in case-control designs: an application to statins and colorectal cancer. International Journal of Epidemiology , 49 (5) pp. 1637-1646. 10.1093/ije/dyaa144. Green open access
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Dickerman, Barbra A; García-Albéniz, Xabier; Logan, Roger W; Denaxas, Spiros; Hernán, Miguel A; (2023) Evaluating Metformin Strategies for Cancer Prevention: A Target Trial Emulation Using Electronic Health Records. Epidemiology , 34 (3) pp. 690-699. 10.1097/EDE.0000000000001626. Green open access
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Dickerman, BA; Garcia-Albeniz, X; Logan, RW; Denaxas, S; Hernan, MA; (2019) Avoidable flaws in observational analyses: an application to statins and cancer. Nature Medicine , 25 (10) pp. 1601-1605. 10.1038/s41591-019-0597-x. Green open access
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Dutey-Magni, P; Gill, MJ; Mcnulty, D; Sohal, G; Hayward, A; Shallcross, L; (2021) Feasibility study of hospital antimicrobial stewardship analytics using electronic health records. JAC-Antimicrobial Resistance , 3 (1) , Article dlab018. 10.1093/jacamr/dlab018. Green open access
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Elkheder, Musaab; Gonzalez-Izquierdo, Arturo; Qummer Ul Arfeen, Muhammad; Kuan, Valerie; Lumbers, R Thomas; Denaxas, Spiros; Shah, Anoop D; (2022) Translating and evaluating historic phenotyping algorithms using SNOMED CT. Journal of the American Medical Informatics Association 10.1093/jamia/ocac158. (In press). Green open access
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Eyre, M; Burns, R; Kirkby, V; Smith, C; Denaxas, S; Nguyen, V; Hayward, A; ... Aldridge, R; + view all (2021) Impact of baseline cases of cough and fever on UK COVID-19 diagnostic testing rates: estimates from the Bug Watch community cohort study [version 2; peer review: 1 approved, 1 approved with reservations]. Wellcome Open Research , 5 , Article 225. 10.12688/wellcomeopenres.16304.2. Green open access
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Eyre, MT; Burns, R; Kirkby, V; Smith, C; Denaxas, S; Nguyen, V; Hayward, A; ... Aldridge, RW; + view all (2020) Impact of baseline cases of cough and fever on UK COVID-19 diagnostic testing rates: estimates from the Bug Watch community cohort study [version 1; peer review: 1 approved, 1 approved with reservations]. Wellcome Open Research , 5 p. 225. 10.12688/wellcomeopenres.16304.1. Green open access
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Farmer, RE; Mathur, R; Schmidt, AF; Bhaskaran, K; Fatemifar, G; Eastwood, SV; Finan, C; ... Chaturvedi, N; + view all (2019) Associations Between Measures of Sarcopenic Obesity and Risk of Cardiovascular Disease and Mortality: A Cohort Study and Mendelian Randomization Analysis Using the UK Biobank. Journal of the American Heart Association , 8 (13) , Article e011638. 10.1161/JAHA.118.011638. Green open access
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Gale, R; Gill, C; Pikoula, M; Lee, AY; Hanson, RLW; Denaxas, S; Egan, C; ... UK EMR Database Users Group; + view all (2020) Multicentre study of 4626 patients assesses the effectiveness, safety and burden of two categories of treatments for central retinal vein occlusion: intravitreal anti-vascular endothelial growth factor injections and intravitreal Ozurdex injections. British Journal of Ophthalmology 10.1136/bjophthalmol-2020-317306. (In press). Green open access
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Gale, R; Pikoula, M; Lee, AY; Denaxas, S; Egan, C; Tufail, A; Taylor, P; (2020) Real world evidence on 5661 patients treated for macular oedema secondary to branch retinal vein occlusion with intravitreal anti-vascular endothelial growth factor, intravitreal dexamethasone or macular laser. British Journal of Ophthalmology 10.1136/bjophthalmol-2020-315836. (In press). Green open access
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Garfield, V; Farmaki, A-E; Fatemifar, G; Eastwood, SV; Mathur, R; Rentsch, CT; Denaxas, S; ... Chaturvedi, N; + view all (2021) The Relationship Between Glycaemia, Cognitive Function, Structural Brain Outcomes and Dementia: A Mendelian Randomisation Study in the UK Biobank. Diabetes 10.2337/db20-0895. (In press). Green open access
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George, J; Mathur, R; Shah, AD; Pujades-Rodriguez, M; Denaxas, S; Smeeth, L; Timmis, A; (2017) Ethnicity and the first diagnosis of a wide range of cardiovascular diseases: Associations in a linked electronic health record cohort of 1 million patients. PLoS ONE , 12 (6) , Article e0178945. 10.1371/journal.pone.0178945. Green open access
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George, J; Rapsomaniki, E; Pujades-Rodriguez, M; Shah, AD; Denaxas, S; Herrett, E; Smeeth, L; ... Hemingway, H; + view all (2015) How Does Cardiovascular Disease First Present in Women and Men? Incidence of 12 Cardiovascular Diseases in a Contemporary Cohort of 1,937,360 People. Circulation , 132 (14) pp. 1320-1328. 10.1161/CIRCULATIONAHA.114.013797. Green open access
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Gho, JMIH; Schmidt, AF; Pasea, L; Koudstaal, S; Pujades-Rodriguez, M; Denaxas, S; Shah, AD; ... Asselbergs, FW; + view all (2018) An electronic health records cohort study on heart failure following myocardial infarction in England: incidence and predictors. BMJ Open , 8 (3) , Article e018331. 10.1136/bmjopen-2017-018331. Green open access
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Godec, Thomas R; Bromage, Daniel I; Pujades-Rodriguez, Mar; Cannatà, Antonio; Gonzalez-Izquierdo, Arturo; Denaxas, Spiros; Hemingway, Harry; ... McDonagh, Theresa A; + view all (2022) Cardiovascular outcomes associated with treatment of type 2 diabetes in patients with ischaemic heart failure. ESC Heart Failure 10.1002/ehf2.13910. (In press). Green open access
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Graul, Emily L; Stone, Philip W; Massen, Georgie M; Hatam, Sara; Adamson, Alexander; Denaxas, Spiros; Peters, Nicholas S; (2023) Determining prescriptions in electronic healthcare record data: methods for development of standardized, reproducible drug codelists. JAMIA Open , 6 (3) , Article ooad078. 10.1093/jamiaopen/ooad078. (In press). Green open access
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Gurdasani, D; Bhatt, S; Costello, A; Denaxas, S; Flaxman, S; Greenhalgh, T; Griffin, S; ... Pagel, C; + view all (2021) Vaccinating adolescents against SARS-CoV-2 in England: a risk-benefit analysis. Journal of the Royal Society of Medicine 10.1177/01410768211052589. (In press). Green open access
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Handy, Alex; Banerjee, Amitava; Wood, Angela M; Dale, Caroline; Sudlow, Cathie LM; Tomlinson, Christopher; Bean, Daniel; ... CVD-COVID-UK Consortium; + view all (2022) Evaluation of antithrombotic use and COVID-19 outcomes in a nationwide atrial fibrillation cohort. Heart 10.1136/heartjnl-2021-320325. (In press). Green open access
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Harrisa, S; Shi, S; Brealey, D; MacCallum, NS; Denaxas, S; Perez-Suarez, D; Ercole, A; ... Singer, M; + view all (2018) Critical Care Health Informatics Collaborative (CCHIC): Data, tools and methods for reproducible research: A multi-centre UK intensive care database. International Journal of Medical Informatics , 112 pp. 82-89. 10.1016/j.ijmedinf.2018.01.006. Green open access
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Hartmann, Sylvia; Yasmeen, Summaira; Jacobs, Benjamin M; Denaxas, Spiros; Pirmohamed, Munir; Gamazon, Eric R; Caulfield, Mark J; ... Langenberg, Claudia; + view all (2023) ADRA2A and IRX1 are putative risk genes for Raynaud's phenomenon. Nature Communications , 14 , Article 6156. 10.1038/s41467-023-41876-5. Green open access
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Hemingway, H; Asselbergs, FW; Danesh, J; Dobson, R; Maniadakis, N; Maggioni, A; van Thiel, GJ; ... BigData@Heart Consortium, .; + view all (2018) Big data from electronic health records for early and late translational cardiovascular research: challenges and potential. European Heart Journal , 39 (16) pp. 1481-1495. 10.1093/eurheartj/ehx487. Green open access
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Hemingway, H; Feder, GS; Fitzpatrick, NK; Denaxas, S; Shah, AD; Timmis, AD; (2017) Using nationwide 'big data' from linked electronic health records to help improve outcomes in cardiovascular diseases: 33 studies using methods from epidemiology, informatics, economics and social science in the ClinicAl disease research using LInked Bespoke studies and Electronic health Records (CALIBER) programme. Programme Grants for Applied Research , 5 (4) xxxvi, 1-329. 10.3310/pgfar05040. Green open access
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Hemingway, H; Lyons, R; Li, Q; Buchan, I; Ainsworth, J; Pell, J; Morris, A; (2020) A national initiative in data science for health: An evaluation of the UK Farr Institute. International Journal of Population Data Science , 5 (1) 10.23889/ijpds.v5i1.1128. Green open access
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Henry, Albert; Mo, Xiaodong; Finan, Chris; Chaffin, Mark D; Speed, Doug; Issa, Hanane; Denaxas, Spiros; ... HERMES Consortium; + view all (2025) Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes. Nature Genetics 10.1038/s41588-024-02064-3. (In press). Green open access
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Henry, A; Katsoulis, M; Masi, S; Fatemifar, G; Denaxas, S; Acosta, D; Garfield, V; (2019) The relationship between sleep duration, cognition, and dementia: A Mendelian randomization study. International Journal of Epidemiology , Article dyz071. 10.1093/ije/dyz071. Green open access
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Herrett, E; George, J; Denaxas, S; Bhaskaran, K; Timmis, A; Hemingway, H; Smeeth, L; (2013) Type and timing of heralding in ST-elevation and non-ST-elevation myocardial infarction: an analysis of prospectively collected electronic healthcare records linked to the national registry of acute coronary syndromes. European Heart Journal: Acute Cardiovascular Care , 2 (3) pp. 235-245. 10.1177/2048872613487495. Green open access
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Hingorani, A; Kuan, V; Finan, C; Kruger, F; Gaulton, A; Chopade, S; Sofat, R; ... Casas, JP; + view all (2017) Flipping the odds of drug development success through human genomics. bioRxiv 10.1101/170142. Green open access
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Hingorani, AD; Kuan, V; Finan, C; Kruger, FA; Gaulton, A; Chopade, S; Sofat, R; ... Casas, JP; + view all (2019) Improving the odds of drug development success through human genomics: modelling study. Scientific Reports , 9 (1) , Article 18911. 10.1038/s41598-019-54849-w. Green open access
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Hopkins, C; Williamson, E; Morris, S; Clarke, CS; Thomas, M; Evans, H; Little, P; ... MACRO programme team; + view all (2019) Antibiotic usage in chronic rhinosinusitis: analysis of national primary care electronic health records. Rhinology , 57 (6) pp. 420-429. 10.4193/Rhin19.136. Green open access
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Howe, LJ; Dudbridge, F; Schmidt, AF; Finan, C; Denaxas, S; Asselbergs, FW; Hingorani, AD; (2020) Polygenic risk scores for coronary artery disease and subsequent event risk amongst established cases. Human Molecular Genetics 10.1093/hmg/ddaa052. (In press). Green open access
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Johnson, R; Evans, M; Cramer, H; Bennert, K; Morris, R; Eldridge, S; Juttner, K; ... Feder, G; + view all (2015) Feasibility and impact of a computerised clinical decision support system on investigation and initial management of new onset chest pain: a mixed methods study. BMC Medical Informatics and Decision Making , 15 , Article 71. 10.1186/s12911-015-0189-8. Green open access
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Jordan, Kelvin P; Rathod-Mistry, Trishna; Bailey, James; Chen, Ying; Clarson, Lorna; Denaxas, Spiros; Hayward, Richard A; ... Mamas, Mamas A; + view all (2022) Long-Term Cardiovascular Risk and Management of Patients Recorded in Primary Care With Unattributed Chest Pain: An Electronic Health Record Study. Journal of the American Heart Association , Article e023146. 10.1161/JAHA.121.023146. Green open access
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Jordan, Kelvin P; Rathod-Mistry, Trishna; van der Windt, Danielle A; Bailey, James; Chen, Ying; Clarson, Lorna; Denaxas, Spiros; ... Mamas, Mamas A; + view all (2023) Determining cardiovascular risk in patients with unattributed chest pain in UK primary care: an electronic health record study. European Journal of Preventive Cardiology , Article zwad055. 10.1093/eurjpc/zwad055. (In press). Green open access
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Jordan, KP; Timmis, A; Croft, P; van der Windt, DA; Denaxas, S; Gonzalez-Izquierdo, A; Hayward, RA; ... Hemingway, H; + view all (2017) Prognosis of undiagnosed chest pain: linked electronic health record cohort study. The BMJ , 357 , Article j1194. 10.1136/bmj.j1194. Green open access
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Josephson, CB; Wiebe, S; Delgado-Garcia, G; Gonzalez-Izquierdo, A; Denaxas, S; Sajobi, TT; Lamidi, M; ... Keezer, MR; + view all (2021) Association of Enzyme-Inducing Antiseizure Drug Use With Long-term Cardiovascular Disease. JAMA Neurology , 78 (11) pp. 1367-1374. 10.1001/jamaneurol.2021.3424.

Josephson, Colin B; Gonzalez-Izquierdo, Arturo; Denaxas, Spiros; Sajobi, Tolulope T; Klein, Karl Martin; Wiebe, Samuel; (2023) Independent Associations of Incident Epilepsy and Enzyme-Inducing and Non–Enzyme-Inducing Antiseizure Medications With the Development of Osteoporosis. JAMA Neurology , 80 (8) pp. 843-850. 10.1001/jamaneurol.2023.1580. Green open access
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Josephson, CB; Gonzalez-Izquierdo, A; Denaxas, S; Fitzpatrick, NK; Sajobi, TT; Engbers, JDT; Patten, S; ... Wiebe, S; + view all (2017) Serotonin reuptake inhibitors and mortality in epilepsy: A linked primary-care cohort study. Epilepsia , 58 (11) pp. 2002-2009. 10.1111/epi.13904. Green open access
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Katsoulis, M; Lai, AG; Diaz-Ordaz, K; Gomes, M; Pasea, L; Banerjee, A; Denaxas, S; ... Hemingway, H; + view all (2021) Identifying adults at high-risk for change in weight and BMI in England: a longitudinal, large-scale, population-based cohort study using electronic health records. The Lancet Diabetes and Endocrinology , 9 (10) pp. 681-694. 10.1016/S2213-8587(21)00207-2. Green open access
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Katsoulis, M; Lai, AG; Kipourou, DK; Gomes, M; Banerjee, A; Denaxas, S; Lumbers, RT; ... Diaz-Ordaz, K; + view all (2023) On the estimation of the effect of weight change on a health outcome using observational data, by utlilising the target trial emulation framework. International Journal of Obesity 10.1038/s41366-023-01396-0. (In press). Green open access
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Katsoulis, M; Pasea, L; Lai, AG; Dobson, RJB; Denaxas, S; Hemingway, H; Banerjee, A; (2021) Obesity during the COVID-19 pandemic: both cause of high risk and potential effect of lockdown? A population-based electronic health record study. Public Health , 191 pp. 41-47. 10.1016/j.puhe.2020.12.003. Green open access
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Katsoulis, M; Denaxas, S; Patel, R; Hemingway, H; (2017) Low-density lipoprotein cholesterol and atrial fibrillation; A Mendelian randomization study using UK-Biobank data. International Journal of Population Data Science , 1 (1) 10.23889/ijpds.v1i1.322. Green open access
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Katsoulis, M; Gomes, M; Lai, AG; Henry, A; Denaxas, S; Lagiou, P; Nafilyan, V; ... Lumbers, RT; + view all (2020) Estimating the effect of reduced attendance at emergency departments for suspected cardiac conditions on cardiac mortality during the COVID-19 pandemic. Circulation: Cardiovascular Quality and Outcomes 10.1161/CIRCOUTCOMES.120.007085. (In press). Green open access
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Katsoulis, M; Stavola, BD; Diaz-Ordaz, K; Gomes, M; Lai, A; Lagiou, P; Wannamethee, G; ... Hemingway, H; + view all (2021) Weight Change and the Onset of Cardiovascular Diseases: Emulating Trials Using Electronic Health Records. Epidemiology , 32 (5) pp. 744-755. 10.1097/EDE.0000000000001393. Green open access
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Kennedy, J; Parker, M; Seaborne, M; Mhereeg, M; Walker, A; Walker, V; Denaxas, S; ... Brophy, S; + view all (2023) Healthcare use attributable to COVID-19: a propensity-matched national electronic health records cohort study of 249,390 people in Wales, UK. BMC Medicine , 21 (1) , Article 259. 10.1186/s12916-023-02897-5. Green open access
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Kerr, S; Bedston, S; Cezard, G; Sampri, A; Murphy, S; Bradley, DT; Morrison, K; ... Sheikh, A; + view all (2024) Undervaccination and severe COVID-19 outcomes: meta-analysis of national cohort studies in England, Northern Ireland, Scotland, and Wales. The Lancet , 403 (10426) pp. 554-566. 10.1016/S0140-6736(23)02467-4. Green open access
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Kotecha, D; Asselbergs, FW; Achenbach, S; Anker, SD; Atar, D; Baigent, C; Banerjee, A; ... Grobbee, DE; + view all (2022) CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research. The BMJ , 378 , Article e069048. 10.1136/bmj-2021-069048. Green open access
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Koudstaal, S; Pujades-Rodriguez, M; Denaxas, S; Gho, JM; Shah, AD; Yu, N; Patel, RS; ... Hemingway, H; + view all (2016) Prognostic burden of heart failure recorded in primary care, acute hospital admissions, or both: a population-based linked electronic health record cohort study in 2.1 million people. European Journal of Heart Failure 10.1002/ejhf.709. (In press). Green open access
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Kuan, Valerie; Denaxas, Spiros; Patalay, Praveetha; Nitsch, Dorothea; Mathur, Rohini; Gonzalez-Izquierdo, Arturo; Sofat, Reecha; ... Multimorbidity Mechanism and Therapeutic Research Collaborative; + view all (2022) Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study. The Lancet Digital Health 10.1016/S2589-7500(22)00187-X. (In press). Green open access
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Kuan, V; Denaxas, S; Gonzalez-Izquierdo, A; Direk, K; Bhatti, O; Husain, S; Sutaria, S; ... Hingorani, A; + view all (2019) A chronological map of 308 physical and mental health conditions from 4 million individuals in the English National Health Service. The Lancet Digital Health , 1 (2) e63-e77. 10.1016/S2589-7500(19)30012-3. Green open access
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Kuan, V; Fraser, HC; Hingorani, M; Denaxas, S; Gonzalez-Izquierdo, A; Direk, K; Nitsch, D; ... Hingorani, AD; + view all (2021) Data-driven identification of ageing-related diseases from electronic health records. Scientific Reports , 11 , Article 2938. 10.1038/s41598-021-82459-y. Green open access
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Lai, AG; Chang, WH; Parisinos, CA; Katsoulis, M; Blackburn, RM; Shah, AD; Nguyen, V; ... Hemingway, H; + view all (2021) An informatics consult approach for generating clinical evidence for treatment decisions. BMC Medical Informatics and Decision Making , 21 (1) , Article 281. 10.1186/s12911-021-01638-z. Green open access
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Lai, AG; Pasea, L; Banerjee, A; Hall, G; Denaxas, S; Chang, WH; Katsoulis, M; ... Hemingway, H; + view all (2020) Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study. BMJ Open , 10 (11) , Article e043828. 10.1136/bmjopen-2020-043828. Green open access
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Lee, IO; Wolstencroft, J; Housby, H; Van den Bree, MBM; Chawner, SJRA; Hall, J; IMAGINE ID Consortium; (2024) The inequity of education, health and care plan provision for children and young people with intellectual and developmental disabilities. Journal of Intellectual Disability Research , 68 (10) pp. 1167-1183. 10.1111/jir.13139. Green open access
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Lewer, D; Padmanathan, P; Qummer ul Arfeen, M; Denaxas, S; Forbes, H; Gonzalez-Izquierdo, A; Hickman, M; (2020) Healthcare use by people who use illicit opioids (HUPIO): development of a cohort based on electronic primary care records in England [version 1; peer review: 2 approved]. Wellcome Open Research , 5 , Article 282. 10.12688/wellcomeopenres.16431.1. Green open access
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Lewer, D; Menezes, D; Cornes, M; Blackburn, RM; Byng, R; Clark, M; Denaxas, S; ... Aldridge, R; + view all (2021) Hospital readmission among people experiencing homelessness in England: a cohort study of 2772 matched homeless and housed inpatients. Journal of Epidemiology & Community Health 10.1136/jech-2020-215204. (In press). Green open access
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Lewer, D; Padmanathan, P; Qummer ul Arfeen, M; Denaxas, S; Forbes, H; Gonzalez-Izquierdo, A; Hickman, M; (2021) Healthcare use by people who use illicit opioids (HUPIO): development of a cohort based on electronic primary care records in England [version 2; peer review: 2 approved]. Wellcome Open Research , 5 p. 282. 10.12688/wellcomeopenres.16431.2. Green open access
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Lhatoo, SD; Bernasconi, N; Blumcke, I; Braun, K; Buchhalter, J; Denaxas, S; Galanopoulou, A; ... Wiebe, S; + view all (2020) Big data in epilepsy: Clinical and research considerations. Report from the Epilepsy Big Data Task Force of the International League Against Epilepsy. Epilepsia , 61 (9) pp. 1869-1883. 10.1111/epi.16633. Green open access
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Lumbers, RT; Shah, S; Lin, H; Czuba, T; Henry, A; Swerdlow, D; Malarstig, A; ... Smith, JG; + view all (2021) The genomics of heart failure: design and rationale of the HERMES consortium. ESC Heart Failure 10.1002/ehf2.13517. (In press). Green open access
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Lyons, J; Akbari, A; Abrams, KR; Azcoaga Lorenzo, A; Ba Dhafari, T; Chess, J; Denaxas, S; ... Owen, RK; + view all (2023) Trajectories in chronic disease accrual and mortality across the lifespan in Wales, UK (2005–2019), by area deprivation profile: linked electronic health records cohort study on 965,905 individuals. The Lancet Regional Health Europe , 32 , Article 100687. 10.1016/j.lanepe.2023.100687. Green open access
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Lyons, J; Akbari, A; Agrawal, U; Harper, G; Azcoaga-Lorenzo, A; Bailey, R; Rafferty, J; ... Lyons, RA; + view all (2021) Protocol for the development of the Wales Multimorbidity e-Cohort (WMC): data sources and methods to construct a population-based research platform to investigate multimorbidity. BMJ Open , 11 (1) , Article e047101. 10.1136/bmjopen-2020-047101. Green open access
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Makadia, Rupa; Shoaibi, Azza; Rao, Gowtham A; Ostropolets, Anna; Rijnbeek, Peter R; Voss, Erica A; Duarte-Salles, Talita; ... Ryan, Patrick B; + view all (2023) Evaluating the impact of alternative phenotype definitions on incidence rates across a global data network. JAMIA Open , 6 (4) , Article ooad096. 10.1093/jamiaopen/ooad096. Green open access
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Mateen, BA; David, AL; Denaxas, S; (2020) Electronic Health Records to Predict Gestational Diabetes Risk. Trends in Pharmacological Sciences , 41 (5) pp. 301-304. 10.1016/j.tips.2020.03.003. Green open access
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Mateen, BA; Wilde, H; Dennis, JM; Duncan, A; Thomas, N; McGovern, A; Denaxas, S; ... Vollmer, S; + view all (2021) Hospital bed capacity and usage across secondary healthcare providers in England during the first wave of the COVID-19 pandemic: a descriptive analysis. BMJ Open , 11 (1) , Article e042945. 10.1136/bmjopen-2020-042945. Green open access
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McGrail, K; Jones, K; Akbari, A; Bennett, T; Boyd, A; Carinci, F; Cui, X; ... Kotelchuck, M; + view all (2018) A Position Statement on Population Data Science: The science of data about people. International Journal of Population Data Science , 3 (4) 10.23889/ijpds.v3i1.415. Green open access
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McMahon, C; Denaxas, S; (2016) A novel framework for assessing metadata quality in epidemiological and public health research settings. AMIA Joint Summits on Translational Science pp. 199-208. Green open access
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McMahon, C; Denaxas, SC; (2019) A novel metadata management model to capture consent for record linkage in longitudinal health research studies. Informatics for Health and Social Care , 44 (2) pp. 176-188. 10.1080/17538157.2017.1364251. Green open access
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Mizani, Mehrdad A; Dashtban, Ashkan; Pasea, Laura; Lai, Alvina G; Thygesen, Johan; Tomlinson, Chris; Handy, Alex; ... CVD-COVID-UK Consortium; + view all (2022) Using national electronic health records for pandemic preparedness: validation of a parsimonious model for predicting excess deaths among those with COVID-19-a data-driven retrospective cohort study. Journal of the Royal Society of Medicine 10.1177/01410768221131897. (In press). Green open access
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Morley, KI; Wallace, J; Denaxas, SC; Hunter, RJ; Patel, RS; Perel, P; Shah, AD; ... Hemingway, H; + view all (2014) Defining disease phenotypes using national linked electronic health records: a case study of atrial fibrillation. PLoS One , 9 (11) , Article e110900. 10.1371/journal.pone.0110900. Green open access
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Owen, Rhiannon K; Lyons, Jane; Akbari, Ashley; Guthrie, Bruce; Agrawal, Utkarsh; Alexander, Daniel C; Azcoaga-Lorenzo, Amaya; ... Abrams, Keith R; + view all (2023) Effect on life expectancy of temporal sequence in a multimorbidity cluster of psychosis, diabetes, and congestive heart failure among 1·7 million individuals in Wales with 20-year follow-up: a retrospective cohort study using linked data. Lancet Public Health , 8 (7) e535-e545. 10.1016/S2468-2667(23)00098-1. Green open access
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Papez, Vaclav; Moinat, Maxim; Voss, Erica A; Bazakou, Sofia; Van Winzum, Anne; Peviani, Alessia; Payralbe, Stefan; ... Denaxas, Spiros; + view all (2023) Transforming and evaluating the UK Biobank to the OMOP Common Data Model for COVID-19 research and beyond. Journal of the American Medical Informatics Association , 30 (1) pp. 103-111. 10.1093/jamia/ocac203. Green open access
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Papez, V; Moinat, M; Payralbe, S; Asselbergs, FW; Lumbers, RT; Hemingway, H; Dobson, R; (2021) Transforming and evaluating electronic health record disease phenotyping algorithms using the OMOP common data model: a case study in heart failure. JAMIA Open , Article ooab001. 10.1093/jamiaopen/ooab001. Green open access
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Pasea, L; Chung, S-C; Pujades-Rodriguez, M; Moayyeri, A; Denaxas, S; Fox, KAA; Wallentin, L; ... Hemingway, H; + view all (2017) Personalising the decision for prolonged dual antiplatelet therapy: development, validation and potential impact of prognosticmodels for cardiovascular events and bleeding in myocardial infarction survivors. European Heart Journal , 38 (14) pp. 1048-1055. 10.1093/eurheartj/ehw683. Green open access
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Pasea, L; Chung, S-C; Pujades-Rodriguez, M; Shah, AD; Alvarez-Madrazo, S; Allan, V; Teo, JT; ... Hemingway, H; + view all (2019) Bleeding in cardiac patients prescribed antithrombotic drugs: electronic health record phenotyping algorithms, incidence, trends and prognosis. BMC Medicine , 17 , Article 206. 10.1186/s12916-019-1438-y. Green open access
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Patel, Riyaz S; Denaxas, Spiros; Howe, Laurence J; Eggo, Rosalind M; Shah, Anoop D; Allen, Naomi E; Danesh, John; ... Hemingway, Harry; + view all (2022) Reproducible disease phenotyping at scale: Example of coronary artery disease in UK Biobank. PLoS One , 17 (4) , Article e0264828. 10.1371/journal.pone.0264828. Green open access
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Pathak, N; Zhang, CX; Boukari, Y; Burns, R; Mathur, R; Gonzalez-Izquierdo, A; Denaxas, S; ... Aldridge, RW; + view all (2021) Development and Validation of a Primary Care Electronic Health Record Phenotype to Study Migration and Health in the UK. International Journal of Environmental Research and Public Health , 18 (24) , Article 13304. 10.3390/ijerph182413304. Green open access
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Pathak, Neha; Zhang, Claire X; Boukari, Yamina; Burns, Rachel; Menezes, Dee; Hugenholtz, Gregory; French, Rebecca S; ... Aldridge, Robert W; + view all (2024) Sexual and reproductive health and rights of migrant women attending primary care in England: A population-based cohort study of 1.2 million individuals of reproductive age (2009–2018). Journal of Migration and Health , 9 , Article 100214. 10.1016/j.jmh.2024.100214. Green open access
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Pathak, N; Patel, P; Burns, R; Haim, L; Zhang, CX; Boukari, Y; Gonzales-Izquierdo, A; ... Aldridge, RW; + view all (2021) Healthcare resource utilisation and mortality outcomes in international migrants to the UK: analysis protocol for a linked population-based cohort study using Clinical Practice Research Datalink (CPRD), Hospital Episode Statistics (HES) and the Office for National Statistics (ONS) [version 2; peer review: 1 approved with reservations, 1 not approved]. Wellcome Open Research , 5 , Article 156. 10.12688/wellcomeopenres.15931.2. Green open access
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Pathak, N; Patel, P; Burns, R; Haim, L; Zhang, CX; Boukari, Y; Gonzales-Izquierdo, A; ... Aldridge, RW; + view all (2020) Healthcare resource utilisation and mortality outcomes in international migrants to the UK: analysis protocol for a linked population-based cohort study using Clinical Practice Research Datalink (CPRD), Hospital Episode Statistics (HES) and the Office for National Statistics (ONS) [version 1; peer review: awaiting peer review]. Wellcome Open Research , 5 , Article 156. 10.12688/wellcomeopenres.15931.1. Green open access
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Philpott, C; Le Conte, S; Beard, D; Cook, J; Sones, W; Morris, S; Clarke, CS; ... MACRO programme team; + view all (2019) Clarithromycin and endoscopic sinus surgery for adults with chronic rhinosinusitis with and without nasal polyps: study protocol for the MACRO randomised controlled trial. Trials , 20 , Article 246. 10.1186/s13063-019-3314-7. Green open access
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Pikoula, Maria; Kallis, Constantinos; Madjiheurem, Sephora; Quint, Jennifer K; Bafadhel, Mona; Denaxas, Spiros; (2023) Evaluation of data processing pipelines on real-world electronic health records data for the purpose of measuring patient similarity. PLoS One , 18 (6) , Article e0287264. 10.1371/journal.pone.0287264. Green open access
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Pikoula, Maria; Quint, Jennifer K; Kallis, Constantinos; Henry, Albert; Denaxas, Spiros; (2025) Identification of clinically meaningful, overlapping obstructive respiratory disease subtypes via data-driven approaches in a primary care population. BMC Pulmonary Medicine , 25 , Article 487. 10.1186/s12890-025-03953-x. Green open access
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Pikoula, M; Jennifer K, Q; Francis, N; Harry, H; Liam, S; Spiros, D; (2019) Identifying clinically important COPD sub-types using data-driven approaches in primary care population based electronic health records. BMC Medical Informatics and Decision Making , 19 (1) , Article 86. 10.1186/s12911-019-0805-0. Green open access
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Pineda-Moncusí, Marta; Allery, Freya; Delmestri, Antonella; Bolton, Thomas; Nolan, John; Thygesen, Johan H; Handy, Alex; ... CVD-COVID-UK/COVID-IMPACT Consortium; + view all (2024) Ethnicity data resource in population-wide health records: completeness, coverage and granularity of diversity. Scientific Data , 11 (1) , Article 221. 10.1038/s41597-024-02958-1. Green open access
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Pita, RD; Pinto, C; Sena, S; Fiaccone, R; Amorim, L; Reis, S; Barreto, M; ... Barreto, ME; + view all (2018) On the Accuracy and Scalability of Probabilistic Data Linkage over the Brazilian 114 Million Cohort. IEEE Journal of Biomedical and Health Informatics 10.1109/JBHI.2018.2796941. (In press). Green open access
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Planell-Morell, P; Bajekal, M; Denaxas, S; Raine, R; Alexander, DC; (2020) Trajectories of Disease Accumulation Using Electronic Health Records. Studies in Health Technology and Informatics , 270 pp. 469-473. 10.3233/SHTI200204. Green open access
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Prugger, Christof; Perier, Marie-Cécile; Gonzalez-Izquierdo, Arturo; Hemingway, Harry; Denaxas, Spiros; Empana, Jean-Philippe; (2023) Incidence of 12 common cardiovascular diseases and subsequent mortality risk in the general population. European Journal of Preventive Cardiology , 30 (15) pp. 1715-1722. 10.1093/eurjpc/zwad192. Green open access
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Pujades-Rodriguez, M; George, J; Shah, AD; Rapsomaniki, E; Denaxas, S; West, R; Smeeth, L; ... Hemingway, H; + view all (2015) Heterogeneous associations between smoking and a wide range of initial presentations of cardiovascular disease in 1 937 360 people in England: lifetime risks and implications for risk prediction. International Journal of Epidemiology , 44 (1) 129 - 141. 10.1093/ije/dyu218. Green open access
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Pujades-Rodriguez, M; Timmis, A; Stogiannis, D; Rapsomaniki, E; Denaxas, S; Shah, A; Feder, G; ... Hemingway, H; + view all (2014) Socioeconomic deprivation and the incidence of 12 cardiovascular diseases in 1.9 million women and men: implications for risk prediction and prevention. PLoS One , 9 (8) , Article e104671. 10.1371/journal.pone.0104671. Green open access
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Rafiq, M; Hayward, A; Warren-Gash, C; Denaxas, S; Gonzalez-Izquierdo, A; Lyratzopoulos, G; Thomas, S; (2019) Allergic disease, corticosteroid use and risk of Hodgkin's lymphoma: A UK Nationwide case-control study. Journal of Allergy and Clinical Immunology 10.1016/j.jaci.2019.10.033. (In press). Green open access
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Rafiq, M; Hayward, A; Warren-Gash, C; Denaxas, S; Gonzalez-Izquierdo, A; Lyratzopoulos, G; Thomas, S; (2019) Socioeconomic deprivation and regional variation in Hodgkin’s lymphoma incidence in the UK: A population-based cohort study of 10 million individuals. BMJ Open , 9 (9) , Article e029228. 10.1136/bmjopen-2019-029228. Green open access
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Rapsomaniki, E; Shah, A; Perel, P; Denaxas, S; George, J; Nicholas, O; Udumyan, R; ... Hemingway, H; + view all (2014) Prognostic models for stable coronary artery disease based on electronic health record cohort of 102 023 patients. Eur Heart J , 35 (13) pp. 844-852. 10.1093/eurheartj/eht533. Green open access
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Rapsomaniki, E; Thuresson, M; Yang, E; Blin, P; Hunt, P; Chung, S-C; Stogiannis, D; ... Hemingway, H; + view all (2016) Using big data from health records from four countries to evaluate chronic disease outcomes: a study in 114 364 survivors of myocardial infarction. European Heart Journal - Quality of Care and Clinical Outcomes , 2 (3) pp. 172-183. 10.1093/ehjqcco/qcw004. Green open access
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Rapsomaniki, E; Timmis, A; George, J; Pujades-Rodriguez, M; Denaxas, S; Shah, AD; Hingorani, A; ... Hemingway, H; + view all (2015) Blood pressure and incidence of twelve cardiovascular diseases; lifetime risks, healthy life-years lost, and age-specific associations in 1.25 million people. The Lancet , 383 (9932) pp. 1899-1911. 10.1016/S0140-6736(14)60685-1. Green open access
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Rapsomaniki, E; Timmis, A; George, J; Pujades-Rodriguez, M; Shah, AD; Denaxas, S; White, IR; ... Hemingway, H; + view all (2014) Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1.25 million people. Lancet , 383 (9932) pp. 1899-1911. 10.1016/S0140-6736(14)60685-1. Green open access
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Schaffer, Andrea L; Park, Robin Y; Tazare, John; Bhaskaran, Krishnan; MacKenna, Brian; Denaxas, Spiros; Dillingham, Iain; ... Walker, Alex; + view all (2024) Changes in sick notes associated with COVID-19 from 2020 to 2022: a cohort study in 24 million primary care patients in OpenSAFELY-TPP. BMJ Open , 14 (7) , Article e080600. 10.1136/bmjopen-2023-080600. Green open access
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Schmidt, AF; Holmes, MV; Preiss, D; Swerdlow, DI; Denaxas, S; Fatemifar, G; Faraway, R; ... Hingorani, AD; + view all (2019) Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9. BMC Cardiovascular Disorders , 19 (1) , Article 240. 10.1186/s12872-019-1187-z. Green open access
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Schwartz, R; Warwick, A; Olvera-Barrios, A; Pikoula, M; Lee, AY; Denaxas, S; Taylor, P; ... of the UK EMR Users Group; + view all (2021) Evolving Treatment Patterns and Outcomes of Neovascular Age-Related Macular Degeneration Over a Decade. Ophthalmology Retina , 5 (8) e11-e22. 10.1016/j.oret.2021.04.001. Green open access
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Scott, J; Bidulka, P; Taylor, DM; Udayaraj, U; Caskey, FJ; Birnie, K; Deanfield, J; ... Nitsch, D; + view all (2023) Management and outcomes of myocardial infarction in people with impaired kidney function in England. BMC Nephrology , 24 (1) , Article 325. 10.1186/s12882-023-03377-x. Green open access
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Shah, AD; Bailey, E; Williams, T; Denaxas, S; Dobson, R; Hemingway, H; (2019) Natural language processing for disease phenotyping in UK primary care records for research: a pilot study in myocardial infarction and death. Journal of Biomedical Semantics , 10 , Article 20. 10.1186/s13326-019-0214-4. Green open access
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Shah, AD; Denaxas, S; Nicholas, O; Hingorani, AD; Hemingway, H; (2017) Neutrophil Counts and Initial Presentation of 12 Cardiovascular Diseases: A CALIBER Cohort Study. Journal of the American College of Cardiology , 69 (9) pp. 1160-1169. 10.1016/j.jacc.2016.12.022. Green open access
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Shah, AD; Denaxas, S; Nicholas, O; Hingorani, AD; Hemingway, H; (2016) Low eosinophil and low lymphocyte counts and the incidence of 12 cardiovascular diseases: a CALIBER cohort study. Open Heart , 3 (2) , Article e000477. 10.1136/openhrt-2016-000477. Green open access
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Shah, AD; Langenberg, C; Rapsomaniki, E; Denaxas, S; Pujades Rodriguez, M; Gale, CP; Deanfield, J; ... Hemingway, H; + view all (2015) Type 2 diabetes and incidence of a wide range of cardiovascular diseases: a cohort study in 1-9 million people. Lancet Diabetes and Endocrinology , 3 (2) pp. 105-113. 10.1016/S2213-8587(14)70219-0. Green open access
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Shah, AD; Thornley, S; Chung, SC; Denaxas, S; Jackson, R; Hemingway, H; (2017) White cell count in the normal range and short-term and long-term mortality: international comparisons of electronic health record cohorts in England and New Zealand. BMJ Open , 7 (2) , Article e013100. 10.1136/bmjopen-2016-013100. Green open access
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Shah, S; Henry, A; Roselli, C; Lin, H; Sveinbjörnsson, G; Fatemifar, G; Hedman, ÅK; ... Lumbers, RT; + view all (2020) Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure. Nature Communications , 11 , Article 163. 10.1038/s41467-019-13690-5. Green open access
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Smith, C; Williams, H; Jhass, A; Patel, S; Crayton, E; Lorencatto, F; Michie, S; ... Shallcross, L; + view all (2020) Antibiotic prescribing in UK care homes 2016-2017: retrospective cohort study of linked data. BMC Health Services Research , 20 , Article 555. Green open access
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Smith, CM; Shallcross, LJ; Dutey-Magni, P; Conolly, A; Fuller, C; Hill, S; Jhass, A; ... PASS research group; + view all (2021) Incidence, healthcare-seeking behaviours, antibiotic use and natural history of common infection syndromes in England: results from the Bug Watch community cohort study. BMC Infectious Diseases , 21 , Article 105. 10.1186/s12879-021-05811-7. Green open access
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Steele, AJ; Denaxas, SC; Shah, AD; Hemingway, H; Luscombe, NM; (2018) Machine learning models in electronic health records can outperform conventional survival models for predicting patient mortality in coronary artery disease. PLoS ONE , 13 (8) , Article e0202344. 10.1371/journal.pone.0202344. Green open access
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Studer, R; Sartini, C; Suzart-Woischnik, K; Agrawal, R; Natani, H; Gill, S; Wirta, SB; ... Kotecha, D; + view all (2021) Identification and mapping real-world data sources for heart failure, acute coronary syndrome, and atrial fibrillation. Cardiology 10.1159/000520674. (In press). Green open access
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Surendran, P; Stewart, ID; Au Yeung, VPW; Pietzner, M; Raffler, J; Wörheide, MA; Li, C; ... Langenberg, C; + view all (2022) Rare and common genetic determinants of metabolic individuality and their effects on human health. Nature Medicine , 28 pp. 2321-2332. 10.1038/s41591-022-02046-0. Green open access
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Takada, T; Nijman, S; Denaxas, S; Snell, KIE; Uijl, A; Nguyen, T-L; Asselbergs, FW; (2021) Internal-external cross-validation helped to evaluate the generalizability of prediction models in large clustered datasets. Journal of Clinical Epidemiology 10.1016/j.jclinepi.2021.03.025. (In press). Green open access
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Tan, Yen Yi; Papez, Vaclav; Chang, Wai Hoong; Mueller, Stefanie H; Denaxas, Spiros; Lai, Alvina G; (2022) Comparing clinical trial population representativeness to real-world populations: an external validity analysis encompassing 43 895 trials and 5 685 738 individuals across 989 unique drugs and 286 conditions in England. The Lancet Healthy Longevity 10.1016/S2666-7568(22)00186-6. (In press). Green open access
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Taylor, Kurt; Eastwood, Sophie; Walker, Venexia; Cezard, Genevieve; Knight, Rochelle; Al Arab, Marwa; Wei, Yinghui; ... Denholm, Rachel; + view all (2024) Incidence of diabetes after SARS-CoV-2 infection in England and the implications of COVID-19 vaccination: a retrospective cohort study of 16 million people. The Lancet Diabetes & Endocrinology , 12 (8) pp. 558-568. 10.1016/S2213-8587(24)00159-1. Green open access
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Terman, Samuel W; Josephson, Colin Bruce; Goyal, Parag; Gonzalez-Izquierdo, Arturo; Morrison, Jean; Denaxas, Spiros; Wiebe, Samuel; (2025) Lamotrigine and Cardiac Arrhythmias: A Target Trial Approach. Neurology , 105 (1) , Article e213640. 10.1212/WNL.0000000000213640.

Uijl, A; Koudstaal, S; Direk, K; Denaxas, S; Groenwold, RHH; Banerjee, A; Hoes, AW; ... Asselbergs, FW; + view all (2019) Risk factors for incident heart failure in age- and sex-specific strata: a population-based cohort using linked electronic health records. European Journal of Heart Failure 10.1002/ejhf.1350. (In press). Green open access
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Uijl, A; Vaartjes, I; Denaxas, S; Hemingway, H; Shah, A; Cleland, J; Grobbee, D; ... Koudstaal, S; + view all (2021) Temporal trends in heart failure medication prescription in a population-based cohort study. BMJ Open , 11 (3) , Article e043290. 10.1136/bmjopen-2020-043290. Green open access
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Van Smeden, Maarten; Heinze, Georg; Van Calster, Ben; Asselbergs, Folkert W; Vardas, Panos E; Bruining, Nico; De Jaegere, Peter; ... Moons, Karel GM; + view all (2022) Critical appraisal of artificial intelligence-based prediction models for cardiovascular disease. European Heart Journal 10.1093/eurheartj/ehac238. (In press). Green open access
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Vasey, Baptiste; Nagendran, Myura; Campbell, Bruce; Clifton, David A; Collins, Gary S; Denaxas, Spiros; Denniston, Alastair K; ... DECIDE-AI expert group; + view all (2022) Reporting guideline for the early stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI. The British Medical Journal , 377 , Article e070904. 10.1136/bmj-2022-070904. Green open access
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Vasey, Baptiste; Nagendran, Myura; Campbell, Bruce; Clifton, David A; Collins, Gary S; Denaxas, Spiros; Denniston, Alastair K; ... DECIDE-AI expert group; + view all (2022) Reporting guideline for the early-stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI. Nature Medicine , 28 pp. 924-933. 10.1038/s41591-022-01772-9. Green open access
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Vauvelle, Andre; Creed, Paidi; Denaxas, Spiros; (2022) Neural-signature methods for structured EHR prediction. BMC Medical Informatics and Decision Making volume , 22 (1) , Article 320. 10.1186/s12911-022-02055-6. Green open access
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Vetrivel, Krishnika; Salejee, Ayesha; Kharunyam, Bheena; Dehbi, Hakim-Moulay; Denaxas, Spiros; Freemantle, Nicholas; Al Wattar, Bassel H; (2025) Predicting the risk of ovarian hyperstimulation syndrome in women undergoing assisted reproductive technology treatments: a systematic review and quality assessment of prediction models. F&S Reviews , 6 (1) , Article 100086. 10.1016/j.xfnr.2024.100086.

Voss, EA; Shoaibi, A; Yin Hui Lai, L; Blacketer, C; Alshammari, T; Makadia, R; Haynes, K; ... Ryan, PB; + view all (2023) Contextualising adverse events of special interest to characterise the baseline incidence rates in 24 million patients with COVID-19 across 26 databases: a multinational retrospective cohort study. eClinicalMedicine , 58 , Article 101932. 10.1016/j.eclinm.2023.101932. Green open access
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Wang, Z; Shah, AD; Tate, AR; Denaxas, S; Shawe-Taylor, J; Hemingway, H; (2012) Extracting diagnoses and investigation results from unstructured text in electronic health records by semi-supervised machine learning. PLOS One , 7 (1) , Article e30412. 10.1371/journal.pone.0030412. Green open access
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Wei, Wei-Qi; Rowley, Robb; Wood, Angela; MacArthur, Jacqueline; Embi, Peter J; Denaxas, Spiros; (2024) Improving reporting standards for phenotyping algorithm in biomedical research: 5 fundamental dimensions. Journal of the American Medical Informatics Association , 31 (4) pp. 1036-1041. 10.1093/jamia/ocae005. Green open access
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Wei, Yinghui; Horne, Elsie Mf; Knight, Rochelle; Cezard, Genevieve; Walker, Alex J; Fisher, Louis; Denholm, Rachel; ... CONVALESCENCE study; + view all (2025) Patient characteristics associated with clinically coded long COVID: an OpenSAFELY study using electronic health records. BJGP Open , Article BJGPO.2024.0140. 10.3399/BJGPO.2024.0140. (In press). Green open access
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Whiteley, William N; Ip, Samantha; Cooper, Jennifer A; Bolton, Thomas; Keene, Spencer; Walker, Venexia; Denholm, Rachel; ... CVD-COVID-UK consortium; + view all (2022) Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: A population-based cohort study of 46 million adults in England. PLOS Med , 19 (2) , Article e1003926. 10.1371/journal.pmed.1003926. Green open access
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Whitfield, E; White, B; Barclay, ME; Rafiq, M; Renzi, C; Rous, B; Denaxas, S; (2025) Differences in recording of cancer diagnosis between datasets in England: A population-based study of linked cancer registration, hospital, and primary care data. Cancer Epidemiology , 94 , Article 102703. 10.1016/j.canep.2024.102703. (In press). Green open access
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Whitfield, Emma; White, Becky; Denaxas, Spiros; Lyratzopoulos, Georgios; (2023) Diagnostic windows in non-neoplastic diseases: a systematic review. British Journal of General Practice 10.3399/BJGP.2023.0044. (In press). Green open access
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Wilde, H; Mellan, T; Hawryluk, I; Dennis, JM; Denaxas, S; Pagel, C; Duncan, A; ... Vollmer, SJ; + view all (2021) The association between mechanical ventilator compatible bed occupancy and mortality risk in intensive care patients with COVID-19: a national retrospective cohort study. BMC Medicine , 19 , Article 213. 10.1186/s12916-021-02096-0. Green open access
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Williamson, E; Denaxas, S; Morris, S; Clarke, C; Thomas, M; EVANS, H; Direk, K; ... Carpenter, J; + view all (2019) Risk of mortality and cardiovascular events following macrolide prescription in chronic rhinosinusitis patients: a cohort study using linked primary care electronic health records. Rhinology , 57 (4) pp. 252-260. 10.4193/Rhin18.237. Green open access
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Wolstencroft, J; Hull, L; Warner, L; Akhtar, TN; Mandy, W; IMAGINE-ID consortium, .; Skuse, D; (2021) 'We have been in lockdown since he was born': a mixed methods exploration of the experiences of families caring for children with intellectual disability during the COVID-19 pandemic in the UK. BMJ Open , 11 (9) , Article e049386. 10.1136/bmjopen-2021-049386. Green open access
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Wolstencroft, Jeanne; Wicks, Francesca; Srinivasan, Ramya; Wynn, Sarah; Ford, Tamsin; Baker, Kate; Chawner, Samuel JRA; ... Raymond, F Lucy; + view all (2022) Neuropsychiatric risk in children with intellectual disability of genetic origin: IMAGINE, a UK national cohort study. The Lancet Psychiatry , 9 (9) pp. 715-724. 10.1016/S2215-0366(22)00207-3. Green open access
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Wood, A; Denholm, R; Hollings, S; Cooper, J; Ip, S; Walker, V; Denaxas, S; ... CVD-COVID-UK consortium, .; + view all (2021) Linked electronic health records for research on a nationwide cohort of more than 54 million people in England: data resource. BMJ , 373 , Article n826. 10.1136/bmj.n826. Green open access
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Wright, F Lucy; Cheema, Kate; Goldacre, Raph; Hall, Nick; Herz, Naomi; Islam, Nazrul; Karim, Zainab; ... CVD-COVID-UK Consortium; + view all (2022) Effects of the COVID-19 pandemic on secondary care for cardiovascular disease in the UK: an electronic health record analysis across three countries. European Heart Journal - Quality of Care and Clinical Outcomes , Article qcac077. 10.1093/ehjqcco/qcac077. (In press). Green open access
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Zhang, Ruiqi; Mamza, Jil Billy; Morris, Tamsin; Godfrey, George; Asselbergs, Folkert W; Denaxas, Spiros; Hemingway, Harry; (2022) Lifetime risk of cardiovascular-renal disease in type 2 diabetes: a population-based study in 473,399 individuals. BMC Medicine , 20 , Article 63. 10.1186/s12916-022-02234-2. Green open access
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Zheng, Sean L; Henry, Albert; Cannie, Douglas; Lee, Michael; Miller, David; McGurk, Kathryn A; Bond, Isabelle; ... Lumbers, R Thomas; + view all (2024) Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy. Nature Genetics , 56 (12) pp. 2646-2658. 10.1038/s41588-024-01952-y. Green open access
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Zhou, S-M; Fernandez-Gutierrez, F; Kennedy, J; Cooksey, R; Atkinson, M; Denaxas, S; Siebert, S; ... Brophy, S; + view all (2016) Defining Disease Phenotypes in Primary Care Electronic Health Records by a Machine Learning Approach: A Case Study in Identifying Rheumatoid Arthritis. PLoS ONE , 11 (5) , Article e0154515. 10.1371/journal.pone.0154515. Green open access
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Book chapter

Forssen, H; Patel, R; Fitzpatrick, N; Hingorani, A; Timmis, A; Hemingway, H; Denaxas, S; (2017) Evaluation of Machine Learning Methods to Predict Coronary Artery Disease Using Metabolomic Data. In: Randell, R and Cornet, R and McCowan, C and Peek, N and Scott, PJ, (eds.) Informatics for Health: Connected Citizen-Led Wellness and Population Health. (pp. 111-115). IOS Press Green open access
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Proceedings paper

Denaxas, Spiros; Liu, Ge; Feng, Qiping; Fatemifar, Ghazaleh; Bastarache, Lisa; Kerchberger, Eric V; Hingorani, Aroon D; ... Hemingway, Harry; + view all (2021) Mapping the Read2/CTV3 controlled clinical terminologies to Phecodes in UK Biobank primary care electronic health records: implementation and evaluation. In: Proceeding of the AMIA Annual Symposium 2021. (pp. pp. 362-371). AMIA (American Medical Informatics Association) Green open access
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Denaxas, S; Gonzalez-Izquierdo, A; Fitzpatrick, N; Direk, K; Hemingway, H; (2019) Phenotyping UK Electronic Health Records from 15 Million Individuals for Precision Medicine: He CALIBER Resource. In: Health Informatics Vision: From Data via Information to Knowledge. (pp. pp. 220-223). IOS Press: Athens, Greece. Green open access
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Denaxas, S; Gonzalez-Izquierdo, A; Pikoula, M; Direk, K; Fitzpatrick, N; Hemingway, H; Smeeth, L; (2017) Methods for Enhancing the Reproducibility of Observational Research Using Electronic Health Records: Preliminary Findings From the Caliber Resource. In: Bamidis, PD and Konstantinidis, ST and Rodrigues, PP, (eds.) Proceedings of the 30th IEEE International Symposium on Computer-Based Medical Systems (IEEE CBMS). (pp. pp. 506-508). IEEE: Thessaloniki, Greece. Green open access
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Denaxas, S; Parkinson, H; Fitzpatrick, N; Sudlow, C; Hemingway, H; (2019) Analyzing the heterogeneity of rule-based EHR phenotyping algorithms in CALIBER and the UK Biobank. In: Wiratunga, N and Coenen, F and Sani, S, (eds.) CEUR Workshop Proceedings vol 2429. (pp. pp. 6-14). CEUR: Macao, China. Green open access
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Denaxas, S; Stenetorp, P; Riedel, S; Pikoula, M; Dobson, R; Hemingway, H; (2018) Application of Clinical Concept Embeddings for Heart Failure Prediction in UK EHR data. In: Proceedings of the 32nd Conference on Neural Information Processing Systems (NIPS 2018). : Montréal, Canada. Green open access
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Denaxas, SC; Fatemifar, G; Patel, R; Hemingway, H; (2017) Deriving research-quality phenotypes from national electronic health records to advance precision medicine: a UK Biobank case-study. In: Proceedings of the BHI-2017 International Conference on Biomedical and Health Informatics. IEEE Engineering in Medicine and Biology Society (EMBS): Orlando, FL, USA. Green open access
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Ibrahim, Z; Wu, H; Bach, K; Dobson, R; Denaxas, S; Wiratunga, N; Massie, S; (2017) Preface: The 2nd International Workshop on Knowledge Discovery in Healthcare Data (KDH). In: Ibrahim, Z and Wu, H and Bach, K and Dobson, R and Denaxas, S and Wiratunga, N and Massie, S and Sani, S, (eds.) KDH@IJCAI 2017: Knowledge Discovery in Healthcare Data: Proceedings of the 2nd International Workshop on Knowledge Discovery in Healthcare Data Co-located with the 26th International Joint Conference on Artificial Intelligence (IJCAI 2017). (pp. pp. 3-4). CEUR Workshop Proceedings: Melbourne, Australia. Green open access
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Mackintosh, M; Gonzalez-Izquierdo, A; Rossor, M; Whitaker, K; Direk, K; Denaxas, S; (2019) Network Structures and Dynamics Of Early Dementia Events Recorded in Primary Care Electronic Health Records. In: Kostkova, P and Wood, C and Bosman, A and Grasso, F and Edelstein, M, (eds.) DPH2019: Proceedings of the International Conference on Digital Public Health. (pp. p. 127). Association for Computing Machinery (ACM): New York, NY, USA. Green open access
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Papež, V; Denaxas, S; Hemingway, H; (2017) Evaluating OpenEHR for Storing Computable Representations of Electronic Health Record Phenotyping Algorithms. In: Proceedings of the 2017 IEEE 30th International Symposium on Computer-Based Medical Systems (CBMS). (pp. pp. 509-514). IEEE: Thessaloniki, Greece. Green open access
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Papez, V; Denaxas, S; Hemingway, H; (2017) Evaluation of Semantic Web Technologies for Storing Computable Definitions of Electronic Health Records Phenotyping Algorithms. In: Proceedings - a conference of the American Medical Informatics Association. AIMA: Washington, DC. Green open access
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Pinto, C; Dantas, R; Sena, S; Reis, S; Fiaccone, R; Amorim, L; Barreto, M; ... Barreto, M; + view all (2017) Accuracy of probabilistic record linkage applied to the Brazilian 100 million cohort project. In: Proceedings of the BHI-2017 International Conference on Biomedical and Health Informatics. IEEE Engineering in Medicine and Biology Society (EMBS): Orlando, FL, USA. Green open access
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Pinto, C; Pita, R; Barbosa, G; Araujo, B; Bertoldo, J; Sena, S; Reis, S; ... Denaxas, S; + view all (2017) Probabilistic integration of large Brazilian socioeconomic and clinical databases. In: Bamidis, PD and Konstantinidis, ST and Rodrigues, PP, (eds.) Proceedings of the 30th IEEE International Symposium on Computer-Based Medical Systems (CBMS). (pp. pp. 515-520). IEEE: New York, USA. Green open access
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Pita, R; Mendonca, E; Reis, S; Barreto, M; Denaxas, S; (2017) A Machine Learning Trainable Model to Assess the Accuracy of Probabilistic Record Linkage. In: Bellatreche, L and Chakravarthy, S, (eds.) Proceedings of the 19th International Conference on Big Data Analytics and Knowledge Discovery: DaWaK 2017. (pp. pp. 214-227). Springer, Cham: Regensburg, Germany. Green open access
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Vauvelle, Andre; Wild, Benjamin; Eils, Roland; Denaxas, Spiros C; (2023) Differentiable sorting for censored time-to-event data. In: Oh, Alice and Naumann, Tristan and Globerson, Amir and Saenko, Kate and Hardt, Moritz and Levine, Sergey, (eds.) Proceedings of the Advances in Neural Information Processing Systems 36 (NeurIPS 2023). Neural Information Processing Systems (In press). Green open access
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Zhe, H; Gonzalez-Izquierdo, A; Denaxas, SC; Sura, A; Guo, Y; Hogan, W; Shenkman, E; (2017) Comparing and Contrasting A Priori and A Posteriori Generalizability Assessment of Clinical Trials on Type 2 Diabetes Mellitus. In: Sarkar, N, (ed.) American Medical Informatics Association (AMIA) 2017 Annual Symposium. Hanley and Belfus, Inc. Green open access
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Working / discussion paper

Katsoulis, M; Lai, AG; Kipourou, D-K; Sofat, R; Gomes, M; Banerjee, A; Denaxas, S; ... Diaz-Ordaz, K; + view all (2020) How to estimate the association between change in a risk factor and a health outcome? ArXiv Green open access
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Conference item

Denaxas, SC; Kunz, H; Smeeth, L; Gonzalez-Izquierdo, A; Boutselakis, H; Pikoula, M; Hemingway, H; (2016) Methods for enhancing the reproducibility of clinical epidemiology research in linked electronic health records: results and lessons learned from the CALIBER platform. Presented at: 2016 International Population Data Linkage Conference (IPDLN), Swansea, UK. Green open access
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Erwood, M; Wicks, F; Wolstencroft, J; Srinivasan, R; Hall, J; Van den Bree, M; Denaxas, S; ... Raymond, FL; + view all (2017) Intellectual disability and copy number variants: mental health in the IMAGINE ID cohort. Presented at: The 20th SSBP International Research Symposium, Oranjerie, Netherlands. Green open access
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Josephson, C; Gonzalez-Iquierdo, A; Denaxas, S; Sajobi, T; Klein, KM; Wiebe, S; (2023) Independent associations of incident epilepsy, enzyme-inducing, and non-enzyme-inducing antiseizure medications with the development of osteoporosis: a population-based analysis. Presented at: 35th International Epilepsy Congress, Dublin, Ireland. Green open access
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Kunz, H; Pasea, L; Denaxas, S; (2019) Classification of atherothrombotic events in myocardial infarctions survivors with supervised machine learning using data from an electronic health record system. Presented at: International Conference on Informatics, Management and Technology in Healthcare, ICIMTH 2019, Athens, Greece. Green open access
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Poster

Mackintosh, M; Denaxas, S; Rossor, M; (2017) Can primary care electronic health records facilitate the prediction of early cognitive decline associated with dementia: a systematic literature review. Presented at: Informatics for Health 2017, Manchester, UK. Green open access
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Dataset

Aldridge, R; (2019) Causes of death among homeless people: a population-based cross-sectional study of linked hospitalisation and mortality data in England. [Dataset]. Wellcome Open: London, UK. Green open access
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This list was generated on Thu Jan 29 11:58:49 2026 GMT.