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Article

Abdelnabi, R; Foo, CS; Kaptein, SJF; Zhang, X; Do, TND; Langendries, L; Vangeel, L; ... Neyts, J; + view all (2021) The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model. EBioMedicine , 72 , Article 103595. 10.1016/j.ebiom.2021.103595. Green open access
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Ashford, F; Best, A; Dunn, SJ; Ahmed, Z; Siddiqui, H; Melville, J; Wilkinson, S; ... Jamrozy, D; + view all (2022) SARS-CoV-2 Testing in the Community: Testing Positive Samples with the TaqMan SARS-CoV-2 Mutation Panel To Find Variants in Real Time. Journal of Clinical Microbiology , 60 (4) , Article e02408-21. 10.1128/jcm.02408-21. Green open access
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Aswad, A; Aimola, G; Wight, D; Roychoudhury, P; Zimmermann, C; Hill, J; Lassner, D; ... Kaufer, BB; + view all (2020) Evolutionary history of endogenous Human Herpesvirus 6 reflects human migration out of Africa. Molecular Biology and Evolution 10.1093/molbev/msaa190. (In press). Green open access
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Atkinson, Laura; Lee, Jack CD; Lennon, Alexander; Shah, Divya; Storey, Nathaniel; Morfopoulou, Sofia; Harris, Kathryn A; ... Brown, Julianne R; + view all (2023) Untargeted metagenomics protocol for the diagnosis of infection from CSF and tissue from sterile sites. Heliyon , 9 (9) , Article E19854. 10.1016/j.heliyon.2023.e19854. Green open access
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Baltas, I; Boshier, FAT; Williams, CA; Bayzid, N; Cotic, M; Guerra-Assunção, JA; Irish-Tavares, D; ... Mahungu, TW; + view all (2021) Post-vaccination COVID-19: A case-control study and genomic analysis of 119 breakthrough infections in partially vaccinated individuals. Clinical Infectious Diseases , Article ciab714. 10.1093/cid/ciab714. (In press). Green open access
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Bate, J; Baker, S; Breuer, J; Chisholm, JC; Gray, J; Hambleton, S; Houlton, A; ... Heath, PT; + view all (2019) PEPtalk2: Results of a pilot randomised controlled trial to compare VZIG and aciclovir as postexposure prophylaxis (PEP) against chickenpox in children with cancer. Archives of Disease in Childhood , 104 (1) pp. 25-29. 10.1136/archdischild-2017-314212. Green open access
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Bekegnran, Cesar P; Driouich, Jean-Selim; Breuer, Judith; Barthelemy, Karine; Giocanti, Madeleine; de Lamballerie, Xavier; Kreins, Alexandra Y; ... Solas, Caroline; + view all (2023) Simultaneous quantitation of favipiravir and its hydroxide metabolite in human plasma and hamster matrices using a UPLC-MS/MS method. Biomedical Chromatography 10.1002/bmc.5689. (In press). Green open access
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Besbassi, Hajar; Garcia-Fogeda, Irene; Quinlivan, Mark; Breuer, Judy; Abrams, Steven; Hens, Niel; Ogunjimi, Benson; (2023) Modeling antibody dynamics following herpes zoster indicates that higher varicella-zoster virus viremia generates more VZV-specific antibodies. Frontiers in Immunology , 14 , Article 1104605. 10.3389/fimmu.2023.1104605. Green open access
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Bharucha, T; Houlihan, CF; Breuer, J; (2019) Herpesvirus Infections of the Central Nervous System. Seminars in Neurology , 39 (3) pp. 369-382. 10.1055/s-0039-1687837. Green open access
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Bharucha, T; Ming, D; Breuer, J; (2017) A critical appraisal of 'Shingrix', a novel herpes zoster subunit vaccine (HZ/Su or GSK1437173A) for varicella zoster virus. Human Vaccines & Immunotherapeutics , 13 (8) pp. 1789-1797. 10.1080/21645515.2017.1317410. Green open access
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Bharucha, T; Oeser, C; Balloux, F; Brown, JR; Carbo, EC; Charlett, A; Chiu, CY; ... Field, N; + view all (2020) STROBE-metagenomics: a STROBE extension statement to guide the reporting of metagenomics studies. Lancet Infectious Diseases , 20 (10) E251-E260. 10.1016/S1473-3099(20)30199-7. Green open access
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Bonanni, P; Breuer, J; Gershon, A; Gershon, M; Hryniewicz, W; Papaevangelou, V; Rentier, B; ... Wutzler, P; + view all (2009) Varicella vaccination in Europe - taking the practical approach. BMC Medicine , 7 , Article 26. 10.1186/1741-7015-7-26. Green open access
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Boshier, FAT; Pang, J; Penner, J; Parker, M; Alders, N; Bamford, A; Grandjean, L; ... Breuer, J; + view all (2021) Evolution of viral variants in remdesivir-treated and untreated SARS-CoV-2-infected pediatrics patients. Journal of Medical Virology 10.1002/jmv.27285. (In press). Green open access
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Boshier, FAT; Venturini, C; Stirrup, O; Guerra-Assunção, JA; Alcolea-Medina, A; Becket, AH; Byott, M; ... COG-UK HOCI Variant Substudy consortium*, The COVID-19 Genomics; + view all (2021) The Alpha variant was not associated with excess nosocomial SARS-CoV-2 infection in a multi-centre UK hospital study. Journal of Infection , 83 (6) pp. 693-700. 10.1016/j.jinf.2021.09.022. Green open access
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Bouwes Bavinck, JN; Feltkamp, MCW; Green, AC; Fiocco, M; Euvrard, S; Harwood, CA; Proby, CM; ... EPI-HPV-UV-CA group, .; + view all (2018) Human papillomavirus and post-transplant cutaneous squamous-cell carcinoma: a multicenter, prospective cohort study. American Journal of Transplantation , 18 (5) pp. 1220-1230. 10.1111/ajt.14537. Green open access
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Bramley, Alexandra; Crocker-Buque, Tim; Breuer, Judith; Mahungu, Tabitha W; (2021) Evidence of the reduction of acute circulating communicable viruses during the SARS-CoV-2 pandemic in London. [Letter]. Journal of Infection , 83 (4) pp. 496-522. 10.1016/j.jinf.2021.08.029. Green open access
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Braspenning, SE; Sadaoka, T; Breuer, J; Verjans, GMGM; Ouwendijk, WJD; Depledge, DP; (2020) Decoding the Architecture of the Varicella-Zoster Virus Transcriptome. mBio , 11 (5) , Article e01568-20. 10.1128/mbio.01568-20. Green open access
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Brenner, N; Mentzer, AJ; Butt, J; Michel, A; Prager, K; Brozy, J; Weissbrich, B; ... Waterboer, T; + view all (2018) Validation of Multiplex Serology detecting human herpesviruses 1-5. PLoS One , 13 (12) , Article e0209379. 10.1371/journal.pone.0209379. Green open access
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Breuer, J; (2018) Molecular Genetic Insights Into Varicella Zoster Virus (VZV), the vOka Vaccine Strain, and the Pathogenesis of Latency and Reactivation. The Journal of Infectious Diseases , 218 (suppl_2) S75-S80. 10.1093/infdis/jiy279. Green open access
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Breuer, J; Pacou, M; Gauthier, A; Brown, MM; (2014) Herpes zoster as a risk factor for stroke and TIA: A retrospective cohort study in the UK. Neurology , 82 (3) pp. 206-212. 10.1212/WNL.0000000000000038. Green open access
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Bridges, R; Correia, S; Wegner, F; Venturini, C; Palser, A; Whiter, RE; Kellam, P; ... Farrell, PJ; + view all (2019) Essential role of inverted repeat in Epstein-Barr virus IR-1 in B cell transformation; geographical variation of the viral genome. Philosophical Transactions Of The Royal Society B-biological Sciences , 374 (1773) , Article 20180299. 10.1098/rstb.2018.0299. Green open access
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Brown, AC; Bryant, JM; Einer-Jensen, K; Holdstock, J; Houniet, DT; Chan, JZ; Depledge, DP; ... Breuer, J; + view all (2015) Rapid Whole-Genome Sequencing of Mycobacterium tuberculosis Isolates Directly from Clinical Samples. Journal of Clinical Microbiology , 53 (7) pp. 2230-2237. 10.1128/JCM.00486-15. Green open access
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Brown, JR; Bharucha, T; Breuer, J; (2018) Encephalitis diagnosis using metagenomics: application of next generation sequencing for undiagnosed cases. Journal of Infection , 76 (3) pp. 225-240. 10.1016/j.jinf.2017.12.014. Green open access
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Brown, JR; Morfopoulou, S; Hubb, J; Emmett, WA; Ip, W; Shah, D; Brooks, T; ... Breuer, J; + view all (2015) Astrovirus VA1/HMO-C: An Increasingly Recognized Neurotropic Pathogen in Immunocompromised Patients. Clin Infect Dis , 60 (6) 881 - 888. 10.1093/cid/ciu940. Green open access
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Brown, JR; Roy, S; Ruis, C; Yara Romero, E; Shah, D; Williams, R; Breuer, J; (2016) Norovirus whole genome sequencing by SureSelect target enrichment: a robust and sensitive method. Journal of Clinical Microbiology , 54 (10) pp. 2530-2537. 10.1128/JCM.01052-16. Green open access
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Brown, JR; Roy, S; Shah, D; Williams, CA; Williams, R; Dunn, H; Hartley, J; ... Breuer, J; + view all (2019) Norovirus transmission dynamics in a paediatric hospital using full genome sequences. Clinical Infectious Diseases , 68 (2) pp. 222-228. 10.1093/cid/ciy438. Green open access
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Brown, JR; Roy, S; Tutill, H; Williams, R; Breuer, J; (2017) Super-infections and relapses occur in chronic norovirus infections. Journal of Clinical Virology , 96 pp. 44-48. 10.1016/j.jcv.2017.09.009. Green open access
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Brown, JR; Shah, D; Breuer, J; (2016) Viral gastrointestinal infections and norovirus genotypes in a paediatric UK hospital, 2014-2015. Journal of Clinical Virology , 84 pp. 1-6. 10.1016/j.jcv.2016.08.298. Green open access
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Brown, L-AK; Clark, I; Brown, JR; Breuer, J; Lowe, DM; (2017) Norovirus infection in primary immune deficiency. Reviews in Medical Virology , 27 (3) 10.1002/rmv.1926. Green open access
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Brown, L-AK; Ruis, C; Clark, I; Roy, S; Brown, JR; Albuquerque, AS; Patel, SY; ... Lowe, DM; + view all (2019) A comprehensive characterization of chronic norovirus infection in immunodeficient hosts. Journal of Allergy and Clinical Immunology , 144 (5) pp. 1450-1453. 10.1016/j.jaci.2019.07.036. Green open access
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Bucciol, G; Moens, L; Payne, K; Wollants, E; Mekahli, D; Levtchenko, E; Vermeulen, F; ... Meyts, I; + view all (2018) Chronic Aichi Virus Infection in a Patient with X-Linked Agammaglobulinemia. Journal of Clinical Immunology , 38 (7) pp. 748-752. 10.1007/s10875-018-0558-z. Green open access
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Buddle, Sarah; Brown, Li-An K; Morfopoulou, Sofia; Torres Montaguth, Oscar Enrique; Scoto, Mariacristina; Herder, Vanessa; Dhawan, Anil; ... Breuer, Judith; + view all (2026) Contaminating plasmid sequences and disrupted vector genomes in the liver following adeno-associated virus gene therapy. Nature Medicine 10.1038/s41591-025-04073-z. (In press). Green open access
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Buddle, Sarah; Torres, Oscar; Morfopoulou, Sofia; Breuer, Judith; Brown, Julianne R; (2025) The use of metagenomics to enhance diagnosis of encephalitis. Expert Review of Molecular Diagnostics pp. 1-18. 10.1080/14737159.2025.2500655. (In press).

Butcher, RMR; Sokana, O; Jack, K; Macleod, CK; Marks, M; Kalae, E; Sui, L; ... Roberts, CH; + view all (2016) Correction: Low Prevalence of Conjunctival Infection with Chlamydia trachomatis in a Treatment-Naïve Trachoma-Endemic Region of the Solomon Islands. [Corrigendum]. PLoS Negl Trop Dis , 10 (10) , Article e0005051. 10.1371/journal.pntd.0005051. Green open access
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Butcher, RMR; Sokana, O; Jack, K; Macleod, CK; Marks, ME; Kalae, E; Sui, L; ... Roberts, CH; + view all (2016) Low Prevalence of Conjunctival Infection with Chlamydia trachomatis in a Treatment-Naive Trachoma-Endemic Region of the Solomon Islands. PLoS Neglected Tropical Diseases , 10 (9) , Article e0004863. 10.1371/journal.pntd.0004863. Green open access
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Butler, Christopher C; Hobbs, FD Richard; Gbinigie, Oghenekome A; Rahman, Najib M; Hayward, Gail; Richards, Duncan B; Dorward, Jienchi; ... PANORAMIC Trial Collaborative, Group; + view all (2023) Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial. Tha Lancet , 401 (10373) pp. 281-193. 10.1016/S0140-6736(22)02597-1. Green open access
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Camiolo, Salvatore; Suarez, Nicolas M; Chalka, Antonia; Venturini, Cristina; Breuer, Judith; Davison, Andrew J; (2021) GRACy: A tool for analysing human cytomegalovirus sequence data. Virus Evolution , 7 (1) , Article veaa099. 10.1093/ve/veaa099. Green open access
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Chan, Michele; Linn, Me Me Nay; O'Hagan, Thomas; Guerra-Assunção, José Afonso; Lackenby, Angie; Workman, Sarita; Dacre, Anna; ... Lowe, David M; + view all (2023) Persistent SARS-CoV-2 PCR Positivity Despite Anti-viral Treatment in Immunodeficient Patients. Journal of Clinical Immunology , 43 pp. 1083-1092. 10.1007/s10875-023-01504-9. Green open access
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Charles, Oscar J; Venturini, Cristina; Gantt, Soren; Atkinson, Claire; Griffiths, Paul; Goldstein, Richard A; Breuer, Judith; (2023) Genomic and geographical structure of human cytomegalovirus. Proceedings of the National Academy of Sciences (PNAS) , 120 (30) , Article e2221797120. 10.1073/pnas.2221797120. Green open access
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Chetty, Kritika; Cheng, Iek; Kaliakatsos, Marios; Gonzalez-Granado, Luis Ignacio; Klapsa, Dimitra; Martin, Javier; Bamford, Alasdair; ... Booth, Claire; + view all (2022) Case report: Novel treatment regimen for enterovirus encephalitis in SCID. Frontiers in Immunology , 13 , Article 930031. 10.3389/fimmu.2022.930031. Green open access
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Chhabra, Preeti; Tully, Damien C; Mans, Janet; Niendorf, Sandra; Barclay, Leslie; Cannon, Jennifer L; Montmayeur, Anna M; ... Vinjé, Jan; + view all (2024) Emergence of Novel Norovirus GII.4 Variant. Emerging Infectious Diseases , 30 (1) pp. 163-167. 10.3201/eid3001.231003. Green open access
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Christiansen, MT; Brown, AC; Kundu, S; Tutill, HJ; Williams, R; Brown, JR; Holdstock, J; ... Breuer, J; + view all (2014) Whole-genome enrichment and sequencing of Chlamydia trachomatis directly from clinical samples. BMC Infect Dis , 14 (1) , Article 591. 10.1186/s12879-014-0591-3. Green open access
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Christiansen, MT; Hullegie, SJ; Schutten, M; Einer-Jensen, K; Tutill, HJ; Breuer, J; Rijnders, BJA; (2017) Use of whole genome sequencing in the Dutch Acute HCV in HIV study: focus on transmitted antiviral resistance. Clinical Microbiology and Infection , 23 (2) 123.e1-123.e4. 10.1016/j.cmi.2016.09.018. Green open access
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Clark, SA; Doyle, R; Lucidarme, J; Borrow, R; Breuer, J; (2018) Targeted DNA enrichment and whole genome sequencing of Neisseria meningitidis directly from clinical specimens. International Journal of Medical Microbiology , 308 (2) pp. 256-262. 10.1016/j.ijmm.2017.11.004. Green open access
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Correia, S; Bridges, R; Wegner, F; Venturini, C; Palser, A; Middeldorp, JM; Cohen, JI; ... Farrell, PJ; + view all (2018) Sequence Variation of Epstein-Barr Virus: Viral Types, Geography, Codon Usage, and Diseases. Journal of Virology , 92 (22) , Article e01132-18. 10.1128/JVI.01132-18. Green open access
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Costa, E; Buxton, J; Brown, J; Templeton, KE; Breuer, J; Johannessen, I; (2016) Fatal disseminated varicella zoster infection following zoster vaccination in an immunocompromised patient. BMJ Case Reports , 2016 10.1136/bcr-2015-212688. (In press). Green open access
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Cudini, J; Roy, S; Houldcroft, CJ; Bryant, JM; Depledge, DP; Tutill, H; Veys, P; ... Breuer, J; + view all (2019) Human cytomegalovirus haplotype reconstruction reveals high diversity due to superinfection and evidence of within-host recombination. Proceedings of the National Academy of Sciences of the United States of America , 116 (12) pp. 5693-5698. 10.1073/pnas.1818130116. Green open access
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Datir, R; Kemp, S; El Bouzidi, K; Mlchocova, P; Goldstein, R; Breuer, J; Towers, GJ; ... Gupta, RK; + view all (2020) In Vivo Emergence of a Novel Protease Inhibitor Resistance Signature in HIV-1 Matrix. mBio , 11 (6) 10.1128/mBio.02036-20. Green open access
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Davidson, Jennifer A; Banerjee, Amitava; Strongman, Helen; Herrett, Emily; Smeeth, Liam; Breuer, Judith; Warren-Gash, Charlotte; (2023) Acute Cardiovascular Events After COVID-19 in England in 2020: A Self-Controlled Case Series Study. Clinical Epidemiology , 15 pp. 911-921. 10.2147/CLEP.S421062. Green open access
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de Vries, JJC; Brown, JR; Fischer, N; Sidorov, IA; Morfopoulou, S; Huang, J; Munnink, BBO; ... Claas, ECJ; + view all (2021) Benchmark of thirteen bioinformatic pipelines for metagenomic virus diagnostics using datasets from clinical samples. Journal of Clinical Virology , 141 , Article 104908. 10.1016/j.jcv.2021.104908. Green open access
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Depledge, D; Gray, E; Kundu, S; Cooray, S; Poulsen, A; Aaby, P; Breuer, J; (2014) Evolution of Cocirculating Varicella-Zoster Virus Genotypes during a Chickenpox Outbreak in Guinea-Bissau. Journal of Virology , 88 (24) pp. 13936-13946. 10.1128/JVI.02337-14. Green open access
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Depledge, DP; Brown, J; Macanovic, J; Underhill, G; Breuer, J; (2016) Viral genome sequencing proves nosocomial transmission of fatal varicella. Journal of Infectious Diseases , 214 (9) pp. 1399-1402. 10.1093/infdis/jiw398. Green open access
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Depledge, DP; Cudini, J; Kundu, S; Atkinson, C; Brown, JR; Haque, T; Houldcroft, CJ; ... Breuer, J; + view all (2018) High Viral Diversity and Mixed Infections in Cerebral Spinal Fluid From Cases of Varicella Zoster Virus Encephalitis. The Journal of Infectious Diseases 10.1093/infdis/jiy358. Green open access
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Depledge, DP; Kundu, S; Jensen, NJ; Gray, ER; Jones, M; Steinberg, S; Gershon, A; ... Breuer, J; + view all (2014) Deep Sequencing of Viral Genomes Provides Insight into the Evolution and Pathogenesis of Varicella Zoster Virus and Its Vaccine in Humans. Molecular Biology and Evolution , 31 (2) pp. 397-409. 10.1093/molbev/mst210. Green open access
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Depledge, DP; Ouwendijk, WJD; Sadaoka, T; Braspenning, SE; Mori, Y; Cohrs, RJ; Verjans, GMGM; (2018) A spliced latency-associated VZV transcript maps antisense to the viral transactivator gene 61. Nature Communications , 9 (1) , Article 1167. 10.1038/s41467-018-03569-2. Green open access
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Depledge, DP; Palser, AL; Watson, SJ; Lai, IY; Gray, ER; Grant, P; Kanda, RK; ... Breuer, J; + view all (2011) Correction: specific capture and whole-genome sequencing of viruses from clinical samples. PLOS One , 7 (1) , Article e27805. 10.1371/annotation/3f1444bc-ab9d-4112-958a-2e068792f26f. Green open access
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Depledge, DP; Palser, AL; Watson, SJ; Lai, IY; Gray, ER; Grant, P; Kanda, RK; ... Breuer, J; + view all (2011) Specific capture and whole-genome sequencing of viruses from clinical samples. PLOS One , 6 (11) , Article e27805. 10.1371/journal.pone.0027805. Green open access
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Depledge, DP; Yamanishi, K; Gomi, Y; Gershon, AA; Breuer, J; (2016) Deep Sequencing of Distinct Preparations of the Live Attenuated Varicella-Zoster Virus Vaccine Reveals a Conserved Core of Attenuating Single-Nucleotide Polymorphisms. Journal of Virology , 90 (19) pp. 8698-8704. 10.1128/JVI.00998-16. Green open access
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Devakumar, D; Bamford, A; Ferreira, MU; Broad, J; Rosch, RE; Groce, N; Breuer, J; ... Abubakar, I; + view all (2018) Infectious causes of microcephaly: epidemiology, pathogenesis, diagnosis, and management. The Lancet Infectious Diseases , 18 (1) e13-e13. 10.1016/S1473-3099(17)30398-5. Green open access
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Doyle, RM; Burgess, C; Williams, R; Gorton, R; Booth, H; Brown, J; Bryant, JM; ... Breuer, J; + view all (2018) Direct whole genome sequencing of sputum accurately identifies drug resistant Mycobacterium tuberculosis faster than MGIT culture sequencing. Journal of Clinical Microbiology 10.1128/JCM.00666-18. (In press). Green open access
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Eckert, SE; Chan, JZ-M; Houniet, D; PATHSEEK consortium, .; Breuer, J; Speight, G; (2016) Enrichment by hybridisation of long DNA fragments for Nanopore sequencing. Microbial Genomics , 2 (9) , Article e000087. 10.1099/mgen.0.000087. Green open access
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El Bouzidi, K; Kemp, SA; Datir, RP; Murtala-Ibrahim, F; Aliyu, A; Kwaghe, V; Frampton, D; ... Gupta, RK; + view all (2020) High prevalence of integrase mutation L74I in West African HIV-1 subtypes prior to integrase inhibitor treatment. Journal of Antimicrobial Chemotherapy 10.1093/jac/dkaa033. Green open access
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Eleftheriou, D; Moraitis, E; Hong, Y; Turmaine, M; Venturini, C; Ganesan, V; Breuer, J; ... Brogan, P; + view all (2019) Microparticle-mediated VZV propagation and endothelial activation: Mechanism of VZV vasculopathy. Neurology 10.1212/WNL.0000000000008885. (In press). Green open access
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Flowers, Paul; Leiser, Ruth; Mapp, Fiona; McLeod, Julie; Stirrup, Oliver; Illingworth, Christopher JR; Blackstone, James; (2023) A qualitative process evaluation using the behaviour change wheel approach: Did a whole genome sequence report form (SRF) used to reduce nosocomial SARS-CoV-2 within UK hospitals operate as anticipated? British Journal of Health Psychology 10.1111/bjhp.12666. Green open access
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Forbes, H; Douglas, I; Finn, A; Breuer, J; Bhaskaran, K; Smeeth, L; Packer, S; ... Warren-Gash, C; + view all (2020) Risk of herpes zoster after exposure to varicella to explore the exogenous boosting hypothesis: self controlled case series study using UK electronic healthcare data. The BMJ , 368 , Article l6987. 10.1136/bmj.l6987. Green open access
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Forbes, HJ; Benjamin, L; Breuer, J; (2017) Correction: The association between human herpesvirus infections and stroke: a systematic review protocol. BMJ Open , 7 (7) , Article e016427. 10.1136/bmjopen-2017-016427corr1. Green open access
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Forbes, HJ; Benjamin, L; Breuer, J; Brown, MM; Langan, SM; Minassian, C; Smeeth, L; ... Warren-Gash, C; + view all (2017) The association between human herpesvirus infections and stroke: a systematic review protocol. BMJ Open , 7 (5) , Article e016427. 10.1136/bmjopen-2017-016427. Green open access
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Forbes, HJ; Williamson, E; Benjamin, L; Breuer, J; Brown, MM; Langan, SM; Minassian, C; ... Warren-Gash, C; + view all (2018) Association of herpesviruses and stroke: Systematic review and meta-analysis. PLoS One , 13 (11) , Article e0206163. 10.1371/journal.pone.0206163. Green open access
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Fragaszy, EB; Quinlivan, M; Breuer, J; Craig, R; Hutchings, S; Kidd, M; Mindell, J; (2015) Population-level susceptibility, severity and spread of pandemic influenza: design of, and initial results from, a pre-pandemic and hibernating pandemic phase study using cross-sectional data from the Health Survey for England (HSE). Public Health Research , 3 (6) 10.3310/phr03060. Green open access
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Fu, Michael X; Ingram, Jennifer; Roberts, Courtney; Nurmi, Visa; Watkins, Emma; Dempsey, Nina; Golubchik, Tanya; ... Harvala, Heli; + view all (2024) Blood donation screening for hepatitis B virus core antibodies: The importance of confirmatory testing and initial implication for rare blood donor groups. Vox Sanguinis 10.1111/vox.13608. (In press). Green open access
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Fu, MX; Simmonds, P; Andreani, J; Baklan, H; Webster, M; Asadi, R; Golubchik, T; ... Harvala, H; + view all (2023) Ultrasensitive PCR system for HBV DNA detection: Risk stratification for occult hepatitis B virus infection in English blood donors. Journal of Medical Virology , 95 (10) , Article e29144. 10.1002/jmv.29144. Green open access
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Gaiottino, J; Giovannoni, G; Breuer, J; Tang, JW; (2019) Chronic-relapsing varicella zoster meningitis – Successfully treated with varicella vaccine. Journal of Infection , 79 (1) pp. 61-74. 10.1016/j.jinf.2019.04.009. Green open access
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Gates, S; Andreani, J; Dewar, R; Smith, DB; Templeton, K; Child, HT; Breuer, J; ... Harvala, H; + view all (2023) Postpandemic rebound of adeno-associated virus type 2 (AAV2) infections temporally associated with an outbreak of unexplained severe acute hepatitis in children in the United Kingdom. Journal of Medical Virology , 95 (7) , Article e28921. 10.1002/jmv.28921. Green open access
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Gbinigie, Oghenekome; Ogburn, Emma; Allen, Julie; Dorward, Jienchi; Dobson, Melissa; Madden, Tracie-Ann; Yu, Ly-Mee; ... Butler, Christopher C; + view all (2023) Platform adaptive trial of novel antivirals for early treatment of COVID-19 In the community (PANORAMIC): protocol for a randomised, controlled, open-label, adaptive platform trial of community novel antiviral treatment of COVID-19 in people at increased risk of more severe disease. BMJ Open , 13 (8) , Article e069176. 10.1136/bmjopen-2022-069176. Green open access
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Ghasemian, Ehsan; Faal, Nkoyo; Pickering, Harry; Sillah, Ansumana; Breuer, Judith; Bailey, Robin L; Mabey, David; (2024) Genomic insights into local-scale evolution of ocular Chlamydia trachomatis strains within and between individuals in Gambian trachoma-endemic villages. Microbial Genomics , 10 (3) , Article 001210. 10.1099/mgen.0.001210. Green open access
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Gil, E; Roy, S; Best, T; Hatcher, J; Breuer, J; (2023) Increasing rhinovirus prevalence in paediatric intensive care patients since the SARS-CoV2 pandemic. Journal of Clinical Virology , 166 , Article 105555. 10.1016/j.jcv.2023.105555. Green open access
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Göbel, K; Pankratz, S; Asaridou, C-M; Herrmann, AM; Bittner, S; Merker, M; Ruck, T; ... Meuth, SG; + view all (2016) Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells. Nature Communications , 7 , Article 11626. 10.1038/ncomms11626. Green open access
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Grant, HE; Roy, S; Williams, R; Tutill, H; Ferns, B; Cane, PA; Carswell, JW; ... Leigh Brown, AJ; + view all (2022) A large population sample of African HIV genomes from the 1980s reveals a reduction in subtype D over time associated with propensity for CXCR4 tropism. Retrovirology , 19 , Article 28. 10.1186/s12977-022-00612-5. Green open access
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Gray, ER; Garson, JA; Breuer, J; Edwards, S; Kellam, P; Pillay, D; Towers, GJ; (2011) No Evidence of XMRV or Related Retroviruses in a London HIV-1-Positive Patient Cohort. PLOS ONE , 6 (3) , Article e18096. 10.1371/journal.pone.0018096. Green open access
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Groom, HCT; Boucherit, VC; Makinson, K; Randal, E; Baptista, S; Hagan, S; Gow, JW; ... Bishop, KN; + view all (2010) Absence of xenotropic murine leukaemia virus-related virus in UK patients with chronic fatigue syndrome. Retrovirology , 7 , Article 10. 10.1186/1742-4690-7-10. Green open access
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Guerra-Assunção, José Afonso; van Kampen, Jeroen JA; Roy, Sunando; Remeijer, Lies; Breuer, Judy; Verjans, Georges MGM; (2021) Cluster of Symptomatic Graft-to-Host Transmission of Herpes Simplex Virus Type 1 in an Endothelial Keratoplasty Setting. Ophthalmology Science , 1 (3) , Article 100051. 10.1016/j.xops.2021.100051. Green open access
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Harbecke, R; Jensen, NJ; Depledge, DP; Johnson, GR; Ashbaugh, ME; Schmid, DS; Breuer, J; ... Oxman, MN; + view all (2020) Recurrent herpes zoster in the Shingles Prevention Study: Are second episodes caused by the same varicella-zoster virus strain? Vaccine , 38 (2) pp. 150-157. 10.1016/j.vaccine.2019.10.038. Green open access
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Heath, G; Depledge, DP; Brown, JR; Hale, AD; Tutil, H; Williams, R; Breuer, J; (2017) Acute Retinal Necrosis Caused by the Zoster Vaccine Virus. Clinical Infectious Diseases , 65 (12) pp. 2122-2125. 10.1093/cid/cix683. Green open access
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Herberg, U; Linden, K; Dewald, O; Gatzweiler, E; Seehase, M; Duerr, GD; Doerner, J; ... Breuer, J; + view all (2016) 3D Real-Time Echocardiography Combined with Mini Pressure Wire Generate Reliable Pressure-Volume Loops in Small Hearts. PLoS One , 11 (10) , Article e0165397. 10.1371/journal.pone.0165397. Green open access
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Ho, Antonia; Orton, Richard; Tayler, Rachel; Asamaphan, Patawee; Herder, Vanessa; Davis, Chris; Tong, Lily; ... Thomson, Emma C; + view all (2023) Adeno-associated virus 2 infection in children with non-A-E hepatitis. Nature 10.1038/s41586-023-05948-2. (In press). Green open access
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Houldcroft, CJ; Beale, MA; Breuer, J; (2017) Clinical and biological insights from viral genome sequencing. [Review]. Nature Reviews Microbiology , 15 (3) pp. 183-192. 10.1038/nrmicro.2016.182. Green open access
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Houldcroft, CJ; Breuer, J; (2015) Tales from the crypt and coral reef: the successes and challenges of identifying new herpesviruses using metagenomics. Front Microbiol , 6 , Article 188. 10.3389/fmicb.2015.00188. Green open access
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Houldcroft, CJ; Breuer, J; Bryant, J; Depledge, D; Margetts, B; Simmonds, J; Nicolaou, S; ... PATHSEEK, .; + view all (2016) Detection of low frequency multi-drug resistance and novel putative maribavir resistance in immunocompromised paediatric patients with cytomegalovirus. Frontiers in Microbiology , 7 , Article 1317. 10.3389/fmicb.2016.01317. Green open access
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Houldcroft, CJ; Roy, S; Morfopoulou, S; Margetts, BK; Depledge, DP; Cudini, J; Shah, D; ... Breuer, J; + view all (2018) Use of Whole-genome Sequencing of Adenovirus in Immunocompromised Paediatric Patients to Identify Nosocomial Transmission and Mixed-genotype Infection. The Journal of Infectious Diseases , 218 (8) pp. 1261-1271. 10.1093/infdis/jiy323. Green open access
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Houlihan, CF; Bharucha, T; Breuer, J; (2019) Advances in molecular diagnostic testing for central nervous system infections. Current Opinion in Infectious Diseases , 32 (3) pp. 244-250. 10.1097/QCO.0000000000000548. Green open access
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Hu, M; Depledge, DP; Flores Cortes, E; Breuer, J; Schang, LM; (2019) Chromatin dynamics and the transcriptional competence of HSV-1 genomes during lytic infections. PLoS Pathogens , 15 (11) , Article e1008076. 10.1371/journal.ppat.1008076. Green open access
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Illingworth, Christopher JR; Guerra-Assuncao, Jose A; Gregg, Samuel; Charles, Oscar; Pang, Juanita; Roy, Sunando; Abdelnabi, Rana; ... Breuer, Judith; + view all (2024) Genetic consequences of effective and suboptimal dosing with mutagenic drugs in a hamster model of SARS-CoV-2 infection. Virus Evolution , 10 (1) , Article veae001. 10.1093/ve/veae001. Green open access
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Illingworth, CJR; Roy, S; Beale, MA; Tutill, H; Williams, R; Breuer, J; (2017) On the effective depth of viral sequence data. Virus Evolution , 3 (2) , Article vex030. 10.1093/ve/vex030. Green open access
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Jackson, Susan; Marshall, Julia L; Mawer, Andrew; Lopez-Ramon, Raquel; Harris, Stephanie A; Satti, Iman; Hughes, Eileen; ... COV-CHIM01 study team; + view all (2024) Safety, tolerability, viral kinetics, and immune correlates of protection in healthy, seropositive UK adults inoculated with SARS-CoV-2: a single-centre, open-label, phase 1 controlled human infection study. The Lancet Microbe 10.1016/S2666-5247(24)00025-9. (In press). Green open access
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Johnson, Sarah May; Hassell, Jane; Manning, Gerard Leslie Peter; Sudhakar, Sniya; Brierley, Joe; Grandjean, Louis; Breuer, Judith; (2024) Acute Post‐Measles Encephalitis in a Returning Traveller: Highlighting the Need for MMR Vaccination. Reviews in Medical Virology , 34 (6) , Article e2588. 10.1002/rmv.2588. Green open access
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Jones, J; Depledge, DP; Breuer, J; Ebert-Keel, K; Elliott, G; (2019) Genetic and phenotypic intrastrain variation in herpes simplex virus type 1 Glasgow strain 17 syn+-derived viruses. Journal of General Virology , 100 (12) pp. 1701-1713. 10.1099/jgv.0.001343. Green open access
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Jones, M; Dry, IR; Frampton, D; Singh, M; Kanda, RK; Yee, MB; Kellam, P; ... Breuer, J; + view all (2014) RNA-seq Analysis of Host and Viral Gene Expression Highlights Interaction between Varicella Zoster Virus and Keratinocyte Differentiation. PLoS Pathogens , 10 (1) , Article e1003896. 10.1371/journal.ppat.1003896. Green open access
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Jones, TPW; Buckland, M; Breuer, J; Lowe, DM; (2019) Viral infection in primary antibody deficiency syndromes. Reviews in Medical Virology , 29 (4) , Article e2049. 10.1002/rmv.2049. Green open access
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Kaptein, SJF; Jacobs, S; Langendries, L; Seldeslachts, L; Ter Horst, S; Liesenborghs, L; Hens, B; ... Delang, L; + view all (2020) Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity. Proceedings of the National Academy of Sciences (PNAS) 10.1073/pnas.2014441117. (In press). Green open access
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Kembou-Ringert, Japhette E; Readman, John; Smith, Claire M; Breuer, Judith; Standing, Joseph F; (2022) Applications of the hollow-fibre infection model (HFIM) in viral infection studies. Journal of Antimicrobial Chemotherapy 10.1093/jac/dkac394. (In press). Green open access
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Kennedy, PGE; Montague, P; Scott, F; Grinfeld, E; Ashrafi, GH; Breuer, J; Rowan, EG; (2013) Varicella-Zoster Viruses Associated with Post-Herpetic Neuralgia Induce Sodium Current Density Increases in the ND7-23 Nav-1.8 Neuroblastoma Cell Line. PLoS ONE , 8 (1) , Article e51570. 10.1371/journal.pone.0051570. Green open access
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Knight, Chanice; Andreani, Julien; Garrett, Neil; Winter, Mark; Golubchik, Tanya; Breuer, Judy; Reynolds, Claire; ... Simmonds, Peter; + view all (2023) Absence of detectable monkeypox virus DNA in 11,000 English blood donations during the 2022 outbreak. Transfusion , 63 (4) pp. 690-695. 10.1111/trf.17266. Green open access
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Kreins, Alexandra Y; Roux, Emma; Pang, Juanita; Cheng, Iek; Charles, Oscar; Roy, Sunando; Mohammed, Reem; ... Breuer, Judith; + view all (2024) Favipiravir induces HuNoV viral mutagenesis and infectivity loss with clinical improvement in immunocompromised patients. Clinical Immunology , Article 109901. 10.1016/j.clim.2024.109901. Green open access
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Lassalle, F; Beale, MA; Bharucha, T; Williams, CA; Williams, RJ; Cudini, J; Goldstein, R; ... Breuer, J; + view all (2020) Whole genome sequencing of Herpes Simplex Virus 1 directly from human cerebrospinal fluid reveals selective constraints in neurotropic viruses. Virus Evolution , 6 (1) , Article veaa012. 10.1093/ve/veaa012. Green open access
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Lassalle, F; Depledge, DP; Reeves, MB; Brown, AC; Christiansen, MT; Tutill, HJ; Williams, RJ; ... Breuer, J; + view all (2016) Islands of linkage in an ocean of pervasive recombination reveals two-speed evolution of human cytomegalovirus genomes. Virus Evolution , 2 (1) , Article vew017. 10.1093/ve/vew017. Green open access
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Leiser, Ruth; McLeod, Julie; Mapp, Fiona; Stirrup, Oliver; Blackstone, James; Illingworth, Christopher JR; Nebbia, Gaia; ... Flowers, Paul; + view all (2025) Insights into the implementation of a whole genome sequencing report form (SRF) to reduce nosocomial SARS-CoV-2 in UK hospitals within an unfolding pandemic: A qualitative process evaluation using normalisation process theory. PLoS ONE , 20 (4) , Article e0321534. 10.1371/journal.pone.0321534. Green open access
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Lindesmith, Lisa C; Brewer-Jensen, Paul D; Conrad, Helen; O'Reilly, Kathleen M; Mallory, Michael L; Kelly, Daniel; Williams, Rachel; ... Baric, Ralph S; + view all (2023) Emergent variant modeling of the serological repertoire to norovirus in young children. Cell Reports Medicine , 4 (3) , Article 100954. 10.1016/j.xcrm.2023.100954. Green open access
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Lindesmith, Lisa C; Brewer-Jensen, Paul D; Mallory, Michael L; Zweigart, Mark R; May, Samantha R; Kelly, Daniel; Williams, Rachel; ... Baric, Ralph S; + view all (2022) Antigenic Site Immunodominance Redirection Following Repeat Variant Exposure. Viruses , 14 (6) , Article 1293. 10.3390/v14061293. Green open access
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Low, N; Unemo, M; Skov Jensen, J; Breuer, J; Stephenson, JM; (2014) Molecular Diagnostics for Gonorrhoea: Implications for Antimicrobial Resistance and the Threat of Untreatable Gonorrhoea. PLoS Med , 11 (2) , Article e1001598. 10.1371/journal.pmed.1001598. Green open access
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Lum, SH; Turner, A; Guiver, M; Bonney, D; Martland, T; Davies, E; Newbould, M; ... Wynn, R; + view all (2016) An emerging opportunistic infection: fatal astrovirus (VA1/HMO-C) encephalitis in a pediatric stem cell transplant recipient. Transplant Infectious Disease , 18 (6) pp. 960-964. 10.1111/tid.12607. Green open access
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Lumby, CK; Zhao, L; Breuer, J; Illingworth, CJR; (2020) A large effective population size for established within-host influenza virus infection. eLife , 9 , Article e56915. 10.7554/eLife.56915. Green open access
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Lumby, CK; Zhao, L; Oporto, M; Best, T; Tutill, H; Shah, D; Veys, P; ... Breuer, J; + view all (2020) Favipiravir and Zanamivir Cleared Infection with Influenza B in a Severely Immunocompromised Child. Clinical Infectious Diseases 10.1093/cid/ciaa023. (In press). Green open access
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Manouchehrinia, A; Tanasescu, R; Kareem, H; Jerca, OP; Jabeen, F; Shafei, R; Breuer, J; ... Constantinescu, CS; + view all (2017) Prevalence of a history of prior varicella/herpes zoster infection in multiple sclerosis. Journal of NeuroVirology , 23 (6) pp. 839-844. 10.1007/s13365-017-0569-1. Green open access
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Mavri, Masa; Kubale, Valentina; Depledge, Daniel P; Zuo, Jianmin; Huang, Christene A; Breuer, Judith; Vrecl, Milka; ... Spiess, Katja; + view all (2022) Epstein-Barr Virus-Encoded BILF1 Orthologues From Porcine Lymphotropic Herpesviruses Display Common Molecular Functionality. Frontiers in Endocrinology , 13 , Article 862940. 10.3389/fendo.2022.862940. Green open access
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Meyts, I; Bucciol, G; Jansen, K; Wollants, E; Breuer, J; (2023) Aichivirus: an Emerging Pathogen in Patients with Primary and Secondary B-Cell Deficiency. Journal of Clinical Immunology , 43 pp. 532-535. 10.1007/s10875-022-01410-6. Green open access
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Morfopoulou, Sofia; Buddle, Sarah; Montaguth, Oscar Enrique Torres; Atkinson, Laura; Guerra-Assunção, José Afonso; Marjaneh, Mahdi Moradi; Chiozzi, Riccardo Zenezini; ... Breuer, Judith; + view all (2023) Genomic investigations of unexplained acute hepatitis in children. Nature 10.1038/s41586-023-06003-w. (In press). Green open access
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Morfopoulou, S; Brown, JR; Davies, EG; Anderson, G; Virasami, A; Qasim, W; Chong, WK; ... Breuer, J; + view all (2016) Human Coronavirus OC43 Associated with Fatal Encephalitis. [Letter]. New England Journal of Medicine , 375 (5) 497-+. 10.1056/NEJMc1509458. Green open access
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Morfopoulou, S; Mee, ET; Connaughton, SM; Brown, JR; Gilmour, K; Chong, WK; Duprex, WP; ... Breuer, J; + view all (2017) Deep sequencing reveals persistence of cell-associated mumps vaccine virus in chronic encephalitis. Acta Neuropathologica , 133 (1) pp. 139-147. 10.1007/s00401-016-1629-y. Green open access
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Nimmo, C; Brien, K; Millard, J; Grant, AD; Padayatchi, N; Pym, AS; O'Donnell, M; ... Balloux, F; + view all (2020) Dynamics of within-host Mycobacterium tuberculosis diversity and heteroresistance during treatment. EBioMedicine , 55 , Article 102747. 10.1016/j.ebiom.2020.102747. Green open access
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Nimmo, C; Doyle, R; Burgess, C; Williams, R; Gorton, R; McHugh, TD; Brown, M; ... Breuer, J; + view all (2017) Rapid identification of a Mycobacterium tuberculosis full genetic drug resistance profile through whole genome sequencing directly from sputum. International Journal of Infectious Diseases , 62 pp. 44-46. 10.1016/j.ijid.2017.07.007. Green open access
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Nimmo, C; Shaw, LP; Doyle, R; Williams, R; Brien, K; Burgess, C; Breuer, J; ... Pym, AS; + view all (2019) Whole genome sequencing Mycobacterium tuberculosis directly from sputum identifies more genetic diversity than sequencing from culture. BMC Genomics , 20 (1) , Article 389. 10.1186/s12864-019-5782-2. Green open access
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O'Reilly, Kathleen M; Sandman, Frank; Allen, David; Jarvis, Christopher; Gimma, Amy; Douglas, Amy; Larkin, Lesley; ... Edmunds, W John; + view all (2021) Predicted norovirus resurgence in 2021-2022 due to the relaxation of nonpharmaceutical interventions associated with COVID-19 restrictions in England: a mathematical modeling study. BMC Medicine , 19 (1) , Article 299. 10.1186/s12916-021-02153-8. Green open access
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Ortiz, Arturo Torres; Kendall, Michelle; Storey, Nathaniel; Hatcher, James; Dunn, Helen; Roy, Sunando; Williams, Rachel; ... Grandjean, Louis; + view all (2023) Within-host diversity improves phylogenetic and transmission reconstruction of SARS-CoV-2 outbreaks. eLife , Article e84384. 10.7554/eLife.84384. (In press). Green open access
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Ouwendijk, WJD; Depledge, DP; Rajbhandari, L; Lenac Rovis, T; Jonjic, S; Breuer, J; Venkatesan, A; ... Sadaoka, T; + view all (2020) Varicella-zoster virus VLT-ORF63 fusion transcript induces broad viral gene expression during reactivation from neuronal latency. Nature Communications , 11 (1) , Article 6324. 10.1038/s41467-020-20031-4. Green open access
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Pang, J; Slyker, JA; Roy, S; Bryant, J; Atkinson, C; Cudini, J; Farquhar, C; ... Breuer, J; + view all (2020) Mixed cytomegalovirus genotypes in HIV positive mothers show compartmentalization and distinct patterns of transmission to infants. Elife , 9 , Article e63199. 10.7554/eLife.63199. (In press). Green open access
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Penner, Justin; Hassell, Jane; Brown, Julianne R; Mankad, Kshitij; Storey, Nathaniel; Atkinson, Laura; Ranganathan, Nisha; ... Morfopoulou, Sofia; + view all (2023) Translating metagenomics into clinical practice for complex paediatric neurological presentations. Journal of Infection , 87 (5) pp. 451-458. 10.1016/j.jinf.2023.08.002. Green open access
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Peters, RPH; Doyle, R; Redelinghuys, MJ; McIntyre, JA; Verjans, GM; Breuer, J; Kock, MM; (2017) Chlamydia trachomatis Biovar L2 Infection in Women in South Africa. Emerg Infect Dis , 23 (11) pp. 1913-1915. 10.3201/eid2311.170758. Green open access
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Pheasant, K; Moller-Levet, CS; Jones, J; Depledge, D; Breuer, J; Elliott, G; (2019) Nuclear-cytoplasmic compartmentalization of the herpes simplex virus 1 infected cell transcriptome is co-ordinated by the viral endoribonuclease vhs and cofactors to facilitate the translation of late proteins. PLoS Pathogens , 14 (11) , Article e1007331. 10.1371/journal.ppat.1007331. (In press). Green open access
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Pickering, H; Chernet, A; Sata, E; Zerihun, M; Williams, CA; Breuer, J; Nute, AW; ... Nash, SD; + view all (2020) Genomics of Ocular Chlamydia trachomatis after 5 years of SAFE interventions for trachoma in Amhara, Ethiopia. The Journal of Infectious Diseases 10.1093/infdis/jiaa615. (In press). Green open access
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Pitt, Rachel; Doyle, Ronan; Theilgaard Christiansen, Mette; Horner, Paddy; Hathorn, Emma; Alexander, Sarah; Woodford, Neil; ... Breuer, Judith; + view all (2022) Whole-genome sequencing of Chlamydia trachomatis isolates from persistently infected patients. International Journal of STD and AIDS 10.1177/09564624211048662. (In press). Green open access
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Roy, S; Hartley, J; Dunn, H; Williams, R; Williams, CA; Breuer, J; (2019) Whole-genome Sequencing Provides Data for Stratifying Infection Prevention and Control Management of Nosocomial Influenza A. Clinical Infectious Diseases 10.1093/cid/ciz020. (In press). Green open access
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Rueeger, Sina; Hammer, Christian; Loetscher, Alexis; McLaren, Paul J; Lawless, Dylan; Naret, Olivier; Depledge, Daniel P; ... Fellay, Jacques; + view all (2021) The influence of human genetic variation on Epstein–Barr virus sequence diversity. Scientific Reports , 11 , Article 4586. 10.1038/s41598-021-84070-7. Green open access
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Ruis, C; Brown, L-AK; Roy, S; Atkinson, C; Williams, R; Burns, SO; Yara-Romero, E; ... Lowe, DM; + view all (2018) Mutagenesis in Norovirus in Response to Favipiravir Treatment. New England Journal of Medicine , 379 (22) pp. 2173-2176. 10.1056/NEJMc1806941. Green open access
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Ruis, C; Roy, S; Brown, JR; Allen, DJ; Goldstein, RA; Breuer, J; (2017) The emerging GII.P16-GII.4 Sydney 2012 norovirus lineage is circulating worldwide, arose by late-2014 and contains polymerase changes that may increase virus transmission. PLoS ONE , 12 (6) , Article e0179572. 10.1371/journal.pone.0179572. Green open access
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Sadaoka, Tomohiko; Depledge, Daniel P; Rajbhandari, Labchan; Breuer, Judith; Venkatesan, Arun; Cohen, Jeffrey; (2022) A Variant Allele in Varicella-Zoster Virus Glycoprotein B Selected during Production of the Varicella Vaccine Contributes to Its Attenuation. Genetics and Molecular Biology , 13 (4) pp. 1-19. 10.1128/mbio.01864-22. Green open access
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Sadaoka, T; Depledge, DP; Rajbhandari, L; Venkatesan, A; Breuer, J; Cohen, JI; (2016) In vitro system using human neurons demonstrates that varicella-zoster vaccine virus is impaired for reactivation, but not latency. Proceedings Of The National Academy Of Sciences Of The United States Of America , 113 (17) E2403-E2412. 10.1073/pnas.1522575113. Green open access
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Sanchez Clemente, Nuria; Penner, Justin; Breuer, Judith; Ip, Winnie; Booth, Claire; (2022) Case Report: A Severe Paediatric Presentation of COVID-19 in APDS2 Immunodeficiency. Frontiers in Immunology , 13 , Article 881259. 10.3389/fimmu.2022.881259. Green open access
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Schneider-Hohendorf, T; Mohan, H; Bien, CG; Breuer, J; Becker, A; Görlich, D; Kuhlmann, T; ... Schwab, N; + view all (2016) CD8(+) T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing. Nature Communications , 7 , Article 11153. 10.1038/ncomms11153. Green open access
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Shah, D; Brown, JR; Lee, JCD; Carpenter, ML; Wall, G; Breuer, J; (2022) Use of a sample-to-result shotgun metagenomics platform for the detection and quantification of viral pathogens in paediatric immunocompromised patients. Journal of Clinical Virology Plus , 2 (2) , Article 100073. 10.1016/j.jcvp.2022.100073. (In press). Green open access
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Standing, Joseph F; Buggiotti, Laura; Guerra-Assuncao, Jose Afonso; Woodall, Maximillian; Ellis, Samuel; Agyeman, Akosua A; Miller, Charles; ... PANORAMIC Virology Group; + view all (2024) Randomized controlled trial of molnupiravir SARS-CoV-2 viral and antibody response in at-risk adult outpatients. Nature Communications , 15 , Article 1652. 10.1038/s41467-024-45641-0. Green open access
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Stirrup, O; Boshier, F; Venturini, C; Guerra-Assunção, JA; Alcolea-Medina, A; Beckett, A; Charalampous, T; ... Breuer, J; + view all (2021) SARS-CoV-2 lineage B.1.1.7 is associated with greater disease severity among hospitalised women but not men: multicentre cohort study. BMJ Open Respiratory Research , 8 (1) , Article e001029. 10.1136/bmjresp-2021-001029. Green open access
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Stirrup, Oliver; Blackstone, James; Mapp, Fiona; MacNeil, Alyson; Panca, Monica; Holmes, Alison; Machin, Nicholas; ... Breuer, Judith; + view all (2022) Effectiveness of rapid SARS-CoV-2 genome sequencing in supporting infection control for hospital-onset COVID-19 infection: multicenter, prospective study. eLife , 11 10.7554/elife.78427. (In press). Green open access
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Stirrup, O; Hughes, J; Parker, M; Partridge, DG; Shepherd, JG; Blackstone, J; Coll, F; ... Breuer, J; + view all (2021) Rapid feedback on hospital onset SARS-CoV-2 infections combining epidemiological and sequencing data. e-Life , 10 10.7554/eLife.65828. (In press). Green open access
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Storey, Nathaniel; Brown, Julianne R; Pereira, Rui PA; O'Sullivan, Denise M; Huggett, Jim F; Williams, Rachel; Breuer, Judith; (2021) Single base mutations in the nucleocapsid gene of SARS-CoV-2 affects amplification efficiency of sequence variants and may lead to assay failure. Journal of Clinical Virology Plus , 1 (3) , Article 100037. 10.1016/j.jcvp.2021.100037. Green open access
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Thomson, E; Ip, CLC; Badhan, A; Christiansen, MT; Adamson, W; Ansari, MA; Bibby, D; ... Simmonds, P; + view all (2016) Comparison of Next-Generation Sequencing Technologies for Comprehensive Assessment of Full-Length Hepatitis C Viral Genomes. Journal Of Clinical Microbiology , 54 (10) pp. 2470-2484. 10.1128/JCM.00330-16. Green open access
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Tommasi, C; Breuer, J; (2022) The Biology of Varicella-Zoster Virus Replication in the Skin. Viruses , 14 (5) , Article 982. 10.3390/v14050982. Green open access
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Torres Montaguth, Oscar Enrique; Buddle, Sarah; Morfopoulou, Sofia; Breuer, Judith; (2025) Clinical metagenomics for diagnosis and surveillance of viral pathogens. Nature Reviews Microbiology 10.1038/s41579-025-01223-5. (In press).

Tunnicliffe, Louis; Weil, Rimona S; Breuer, Judith; Rodriguez-Barradas, Maria C; Smeeth, Liam; Rentsch, Christopher T; Warren-Gash, Charlotte; (2024) Herpes Zoster and Risk of Incident Parkinson's Disease in US Veterans: A Matched Cohort Study. Movement Disorders 10.1002/mds.29701. (In press). Green open access
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Vandenberg, O; Kozlakidis, Z; Schrenzel, J; Struelens, MJ; Breuer, J; (2018) Control of Infectious Diseases in the Era of European Clinical Microbiology Laboratory Consolidation: New Challenges and Opportunities for the Patient and for Public Health Surveillance. Frontiers in Medicine , 5 , Article 15. 10.3389/fmed.2018.00015. Green open access
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Venturini, C; Houldcroft, CJ; Lazareva, A; Wegner, F; Morfopoulou, S; Amrolia, PJ; Golwala, Z; ... Breuer, J; + view all (2021) Epstein-Barr virus (EBV) deletions as biomarkers of response to treatment of chronic active EBV. British Journal of Haematology 10.1111/bjh.17790. (In press). Green open access
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Venturini, Cristina; Colston, Julia M; Charles, Oscar; Lankina, Anastasia; Best, Timothy; Atkinson, Claire; Forrest, Calum; ... Breuer, Judith; + view all (2024) Persistent Low-Level Variants in a Subset of Viral Genes Are Highly Predictive of Poor Outcome in Immunocompromised Patients With Cytomegalovirus Infection. The Journal of Infectious Diseases 10.1093/infdis/jiae001. (In press). Green open access
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Warren-Gash, C; Williamson, E; Shiekh, SI; Borjas-Howard, J; Pearce, N; Breuer, JM; Smeeth, L; (2022) No evidence that herpes zoster is associated with increased risk of dementia diagnosis. Annals of Clinical and Translational Neurology 10.1002/acn3.51525. (In press). Green open access
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Warren-Gash, C; Breuer, J; (2019) Herpes zoster in people who are immunocompromised: what are the options for prevention? Lancet Infectious Diseases , 19 (9) pp. 922-924. 10.1016/S1473-3099(19)30399-8. Green open access
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Warren-Gash, C; Breuer, J; (2016) A new herpes zoster subunit vaccine for older adults. Nature Reviews Neurology , 12 (12) pp. 682-683. 10.1038/nrneurol.2016.168. Green open access
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Warren-Gash, C; Forbes, H; Breuer, J; (2017) Varicella and herpes zoster vaccine development: lessons learned. Expert Rev Vaccines , 16 (12) pp. 1191-1201. 10.1080/14760584.2017.1394843. Green open access
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Warren-Gash, C; Forbes, H; Breuer, J; Hayward, AC; Mavrodaris, A; Ridha, BH; Rossor, M; ... Smeeth, L; + view all (2017) Association between human herpesvirus infections and dementia or mild cognitive impairment: a systematic review protocol. BMJ Open , 7 (6) , Article e016522. 10.1136/bmjopen-2017-016522. Green open access
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Warren-Gash, C; Forbes, H; Maple, P; Quinlivan, M; Breuer, J; (2018) Viral load and antibody boosting following herpes zoster diagnosis. Journal of Clinical Virology , 103 pp. 12-15. 10.1016/j.jcv.2018.03.010. Green open access
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Warren-Gash, C; Forbes, HJ; Williamson, E; Breuer, J; Hayward, AC; Mavrodaris, A; Ridha, BH; ... Smeeth, L; + view all (2019) Human herpesvirus infections and dementia or mild cognitive impairment: a systematic review and meta-analysis. Scientific Reports , 9 (1) , Article 4743. 10.1038/s41598-019-41218-w. Green open access
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Watson, SJ; Welkers, MR; Depledge, DP; Coulter, E; Breuer, JM; de Jong, MD; Kellam, P; (2013) Viral population analysis and minority-variant detection using short read next-generation sequencing. Philosophical transactions of the Royal Society of London. Series B, Biological sciences , 368 (1614) , Article 20120205. 10.1098/rstb.2012.0205. Green open access
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Wegner, F; Lassalle, F; Depledge, DP; Balloux, F; Breuer, J; (2019) Co-evolution of sites under immune selection shapes Epstein-Barr Virus population structure. Molecular Biology and Evolution 10.1093/molbev/msz152. (In press). Green open access
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Weinert, LA; Depledge, DP; Kundu, S; Gershon, AA; Nichols, RA; Balloux, F; Welch, JJ; (2015) Rates of vaccine evolution show strong effects of latency: implications for varicella zoster virus epidemiology. Molecular Biology and Evolution , 32 (4) 1020 - 1028. 10.1093/molbev/msu406. Green open access
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Werner, RN; Nikkels, AF; Marinovic, B; Schaefer, M; Czarnecka-Operacz, M; Agius, AM; Bata-Csorgo, Z; ... Nast, A; + view all (2016) European consensus-based (S2k) Guideline on the Management of Herpes Zoster - guided by the European Dermatology Forum (EDF) in cooperation with the European Academy of Dermatology and Venereology (EADV), Part 1: Diagnosis. Journal of the European Academy of Dermatology and Venereology , 31 (1) pp. 9-19. 10.1111/jdv.13995. Green open access
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Werner, RN; Nikkels, AF; MarinoviC, B; Schaefer, M; Czarnecka-Operacz, M; Agius, AM; Bata-Csorgo, Z; ... Nast, A; + view all (2016) European consensus-based (S2k) Guideline on the Management of Herpes Zoster - guided by the European Dermatology Forum (EDF) in cooperation with the European Academy of Dermatology and Venereology (EADV), Part 2: Treatment. Journal of the European Academy of Dermatology and Venereology , 31 (1) pp. 20-29. 10.1111/jdv.13957. Green open access
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Wilkinson, SAJ; Sparks, N; Kele, B; Peacock, TP; Robson, SC; Connor, TR; Loman, NJ; ... Aigrain, L; + view all (2022) Recurrent SARS-CoV-2 mutations in immunodeficient patients. Virus Evolution , 8 (2) 10.1093/ve/veac050. Green open access
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Woodall, Maximillian; Ellis, Samuel; Zhang, Shengyuan; Kembou-Ringert, Japhette; Kite, Kerry-Anne; Buggiotti, Laura; Jacobs, Amy I; ... Smith, Claire M; + view all (2025) Efficient in vitro assay for evaluating drug efficacy and synergy against emerging SARS-CoV-2 strains. Antimicrobial Agents and Chemotherapy , 69 (2) 10.1128/aac.01233-24. Green open access
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Woodall, Maximillian NJ; Cujba, Ana-Maria; Worlock, Kaylee B; Case, Katie-Marie; Masonou, Tereza; Yoshida, Masahiro; Polanski, Krzysztof; ... Smith, Claire M; + view all (2024) Author Correction: Age-specific nasal epithelial responses to SARS-CoV-2 infection. Nature Microbiology , 9 (11) , Article 3076. 10.1038/s41564-024-01757-z. Green open access
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Woodall, Maximillian NJ; Cujba, Ana-Maria; Worlock, Kaylee B; Case, Katie-Marie; Masonou, Tereza; Yoshida, Masahiro; Polanski, Krzysztof; ... Smith, Claire M; + view all (2024) Age-specific nasal epithelial responses to SARS-CoV-2 infection. Nature Microbiology 10.1038/s41564-024-01658-1. (In press). Green open access
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Xavier Lopez-Labrador, F; Brown, JR; Fischer, N; Harvala, H; Van Boheemen, S; Cinek, O; Sayiner, A; ... de Vries, JJC; + view all (2021) Recommendations for the introduction of metagenomic high-throughput sequencing in clinical virology, part I: Wet lab procedure. jJournal of Clinical Virology , 134 , Article 104691. 10.1016/j.jcv.2020.104691. Green open access
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Working / discussion paper

Blackstone, J; Stirrup, O; Mapp, F; Panca, M; Copas, A; Flowers, P; Hockey, L; ... the COVID-19 Genomics UK (COG-UK) Consortium; + view all (2021) Protocol for the COG-UK hospital onset COVID-19 infection (HOCI) multicentre interventional clinical study: evaluating the efficacy of rapid genome sequencing of SARS-CoV-2 in limiting the spread of COVID-19 in United Kingdom NHS hospitals. MedRxiv: Cold Spring Harbor, NY, USA. Green open access
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Ortiz, Arturo Torres; Kendall, Michelle; Storey, Nathaniel; Hatcher, James; Dunn, Helen; Roy, Sunando; Williams, Rachel; ... Grandjean, Louis; + view all (2022) Within-host diversity improves phylogenetic and transmission reconstruction of SARS-CoV-2 outbreaks. BioRxiv: Cold Spring Harbor, NY, USA. Green open access
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Venturini, Cristina; Colston, Julia; Charles, Oscar; Best, Timothy; Atkinson, Claire; Forrest, Calum; Williams, Charlotte; ... Breuer, Judith; + view all (2022) Persistent low-level variants in a subset of HCMV genes are highly predictive of poor outcome in immunocompromised patients with cytomegalovirus infection. MedRxiv: Cold Spring Harbor, NY, USA. Green open access
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Conference item

Higgins, Colin; Petrushkin, Harry; Solebo, Ameenat L; Moore, William; Boyle, Sheila; Arslan, Zainab; Stojanovic, Jelena; ... Marks, Stephen D; + view all (2023) Epstein-barr virus anterior uveitis in a paediatric kidney transplant recipient. Presented at: 55th ESPN Annual Meeting, Vilnius, Lithuania. Green open access
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Lum, SH; Turner, A; Bonney, D; Guiver, M; Breuer, J; Wynn, R; (2016) An emerging opportunistic infection: fatal animal-astrovirus encephalitis in a paediatric stem cell transplant recipient. Presented at: 42nd Annual Meeting of the European Society for Blood and Marrow Transplantation, Valencia, Spain. Green open access
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Thesis

Brown, JR; (2017) Next generation sequencing to understand norovirus in immunocompromised children. Doctoral thesis , UCL (University College London). Green open access
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This list was generated on Sun Feb 1 07:17:58 2026 GMT.