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Acute Retinal Necrosis Caused by the Zoster Vaccine Virus

Heath, G; Depledge, DP; Brown, JR; Hale, AD; Tutil, H; Williams, R; Breuer, J; (2017) Acute Retinal Necrosis Caused by the Zoster Vaccine Virus. Clinical Infectious Diseases , 65 (12) pp. 2122-2125. 10.1093/cid/cix683. Green open access

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Abstract

We report acute retinal necrosis caused by the vaccine Oka strain following immunization of a 78-year-old woman with live zoster vaccine. Whole genome sequencing confirmed the ocular vOka strain to be derived from the vaccine and excluded the presence of new mutations or recombination with wild-type Varicella zoster virus.

Type: Article
Title: Acute Retinal Necrosis Caused by the Zoster Vaccine Virus
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/cid/cix683
Publisher version: https://doi.org/10.1093/cid/cix683
Language: English
Additional information: This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: Science & Technology, Life Sciences & Biomedicine, Immunology, Infectious Diseases, Microbiology, Varicella zoster virus, zoster, shingles, vaccine, retinitis, HERPES-ZOSTER, SAFETY
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Infection, Immunity and Inflammation Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10040252
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