Browse by UCL people
2025
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Anker, Stefan D;
Robertson, Michele;
McMurray, John JV;
Jhund, Pardeep S;
White, Claire;
Reid, Chante;
Bhandari, Sunil;
... Ford, Ian; + view all
(2025)
Recurrent event analyses in patients receiving maintenance dialysis and the effect of higher- versus lower-dose chronic intravenous iron therapy: A report focusing on heart failure events from the PIVOTAL trial.
European Journal of Heart Failure
10.1002/ejhf.3670.
(In press).
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Bakker, WM;
Heerspink, HJL;
Jongs, N;
Correa-Rotter, R;
Rossing, P;
Toto, RD;
Wheeler, DC;
... Vart, P; + view all
(2025)
Effects of Dapagliflozin on Health-Related Quality of Life in Patients with CKD.
Journal of the American Society of Nephrology
10.1681/ASN.0000000776.
(In press).
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Briggs, Juliet;
Ralston, Elizabeth;
Wilkinson, Thomas J;
Walklin, Christy;
Mangahis, Emmanuel;
Young, Hannah ML;
Castle, Ellen M;
... Greenwood, Sharlene A; + view all
(2025)
Digital physical activity intervention via the Kidney BEAM platform in patients with polycystic kidney disease: a randomized controlled trial.
Clinical Kidney Journal
, 18
(3)
, Article sfaf041. 10.1093/ckj/sfaf041.
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Garcia Sanchez, JJ;
Priest, S;
Guiang, H;
Zara, A;
Wheeler, DC;
Moura, AF;
Johnston-Webber, C;
(2025)
Response to the Letter to the Editor Entitled “IMPACT CKD – All Roads Must Not Lead to Dialysis”.
[Letter].
Kidney International Reports
, 10
(8)
pp. 2886-2887.
10.1016/j.ekir.2025.06.026.
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Gonzalez, Andrea Matus;
Cazzolli, Rosanna;
Madero, Magdalena;
Evangelidis, Nicole;
Howell, Martin;
Sautenet, Benedicte;
Bernier-Jean, Amelie;
... SONG-CKD Stakeholder Workshop, Investigators; + view all
(2025)
A Core Outcome Set for Trials in CKD: Report of the Standardized Outcomes in Nephrology-Chronic Kidney Disease (SONG-CKD) Stakeholder Workshops.
American Journal of Kidney Diseases
, 85
(6)
pp. 745-753.
10.1053/j.ajkd.2024.10.013.
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Habte-Asres, Hellena Hailu;
Rosenthal, Miranda;
Nitsch, Dorothea;
Wheeler, David C;
(2025)
Closing the policy gap in diabetes care for individuals with advanced CKD.
Diabetic Medicine
, 42
(2)
, Article e15381. 10.1111/dme.15381.
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Heerspink, HJL;
Chertow, GM;
Rossing, P;
Correa-Rotter, R;
Sjöström, CD;
Toto, RD;
Wheeler, DC;
(2025)
Effects of Dapagliflozin on Progression of Chronic Kidney Disease According to Different Rates of Pre-Trial Progression.
Clinical Journal of the American Society of Nephrology
10.2215/CJN.0000000810.
(In press).
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Hughes, Anastasia;
Ju, Angela;
Cazzolli, Rosanna;
Howell, Martin;
Guha, Chandana;
Levin, Adeera;
Manera, Karine;
... Jaure, Allison; + view all
(2025)
Patient-reported outcome measures for fatigue in patients with chronic kidney disease: a systematic review.
BMJ Open
, 15
(7)
, Article e099592. 10.1136/bmjopen-2025-099592.
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Markham-Lee, Zoe;
Bhagat-Jones, Swati;
Carlton, Jill;
Frankel, Andrew;
Fraser, Simon;
Habte-Asres, Hellena H;
Hill, Claire;
... Hills, Claire E; + view all
(2025)
Research recommendations from the 2024 Breakthrough T1D, Diabetes UK and Kidney Research UK, diabetes and kidney disease expert workshop.
Diabetic Medicine
, Article e70013. 10.1111/dme.70013.
(In press).
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McDonnell, Thomas;
Kalra, Philip A;
Vuilleumier, Nicolas;
Cockwell, Paul;
Wheeler, David C;
Fraser, Simon DS;
Banks, Rosamonde E;
(2025)
The Impact of Primary Renal Diagnosis on Prognosis and the Varying Predictive Power of Albuminuria in the NURTuRE-CKD Study.
American Journal of Nephrology
, 56
(1)
pp. 1-12.
10.1159/000541770.
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Mcewan, Phil;
Foos, Volker;
Roberts, Geraint;
Jenkins, Robert H;
Evans, Marc;
Wheeler, David C;
Chen, Jieling;
(2025)
Beyond glycated haemoglobin: Modelling contemporary management of type 2 diabetes with the updated Cardiff model.
Diabetes, Obesity and Metabolism
, 27
(4)
pp. 1752-1761.
10.1111/dom.16141.
(In press).
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Molad, Jeremy;
Miwa, Kaori;
Nash, Philip S;
Ambler, Gareth;
Best, Jonathan;
Wilson, Duncan;
Hallevi, Hen;
... Koga, Masatoshi; + view all
(2025)
Increased risk of recurrent stroke in patients with impaired kidney function: results of a pooled analysis of individual patient data from the MICON international collaboration.
Journal of Neurology, Neurosurgery and Psychiatry
10.1136/jnnp-2024-335110.
(In press).
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Nash, PS;
Dehbi, HM;
Ahmed, N;
Arram, L;
Best, JG;
Balogun, M;
Bennett, K;
... OPTIMAS Investigators; + view all
(2025)
Anticoagulation Timing in Acute Stroke With Atrial Fibrillation According to Chronic Kidney Disease: The OPTIMAS Trial.
Stroke
, 56
(8)
pp. 1970-1979.
10.1161/STROKEAHA.125.051457.
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Onoja, Anthony;
McDonnell, Thomas;
Annessi, Isabelle;
Banks, Rosamonde E;
Bergin, Marianne;
Cockwell, Paul;
Dusaulcy, Rodolphe;
... Geifman, Nophar; + view all
(2025)
Biomarkers of Kidney Failure and All-Cause Mortality in CKD.
Journal of the American Society of Nephrology
10.1681/ASN.0000000767.
(In press).
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Oshima, M;
Buizen, L;
Jongs, N;
Levin, A;
Chertow, GM;
Wheeler, DC;
Heerspink, HJL;
... Neuen, BL; + view all
(2025)
SGLT2 Inhibition and Hospitalizations in Patients with CKD: A Meta-Analysis of Kidney Outcome Trials.
Clinical Journal of the American Society of Nephrology
10.2215/CJN.0000000771.
(In press).
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Pogson, Cathy Margaret;
Austin, Rosalynn;
Patel, Jignesh Prakash;
Wheeler, David Collins;
(2025)
Medication review interventions for adults living with advanced chronic kidney disease: A scoping review.
British Journal of Clinical Pharmacology
, 91
(4)
pp. 1132-1156.
10.1111/bcp.16363.
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Pollock, Carol;
Carrero, Juan-Jesus;
Kanda, Eiichiro;
Ofori-Asenso, Richard;
Chen, Hungta;
Garcia Sanchez, Juan Jose;
Pentakota, Surendra;
... Wheeler, David C; + view all
(2025)
Correction: Baseline Characteristics of the DISCOVER CKD Prospective Cohort.
[Corrigendum].
Advances in Therapy
10.1007/s12325-025-03107-9.
(In press).
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Wasehuus, Victor;
Smeijer, J David;
Ambery, Phil;
Greasley, Peter J;
Wijkmark, Emma;
Wheeler, David C;
Rossing, Peter;
(2025)
Effects of combined treatment with zibotentan and dapagliflozin compared to dapagliflozin alone in patients with diabetic and non-diabetic chronic kidney disease.
Diabetes, Obesity and Metabolism
10.1111/dom.16468.
(In press).
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2024
Ålund, Oskar;
Unwin, Robert;
Challis, Benjamin;
Kalra, Philip A;
Taal, Maarten W;
Wheeler, David C;
Fraser, Simon DS;
... Söderberg, Magnus; + view all
(2024)
A note on performance metrics for the Kidney Failure Risk Equation.
Nephrology Dialysis Transplantation
, 39
(9)
pp. 1523-1525.
10.1093/ndt/gfae098.
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Apperloo, Ellen M;
Neuen, Brendon L;
Fletcher, Robert A;
Jongs, Niels;
Anker, Stefan D;
Bhatt, Deepak L;
Butler, Javed;
... Heerspink, Hiddo JL; + view all
(2024)
Efficacy and safety of SGLT2 inhibitors with and without glucagon-like peptide 1 receptor agonists: a SMART-C collaborative meta-analysis of randomised controlled trials.
The Lancet Diabetes & Endocrinology
, 12
(8)
pp. 545-557.
10.1016/S2213-8587(24)00155-4.
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Cardoza, Kathryn;
Kang, Amy;
Smyth, Brendan;
Yi, Tae Won;
Pollock, Carol;
Agarwal, Rajiv;
Bakris, George;
... Mahaffey, Kenneth W; + view all
(2024)
Geographic and racial variability in kidney, cardiovascular and safety outcomes with canagliflozin: A secondary analysis of the CREDENCE randomized trial.
Diabetes, Obesity and Metabolism
, 26
(9)
pp. 3530-3540.
10.1111/dom.15685.
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Chertow, Glenn M;
Chang, Anna Marie;
Felker, G Michael;
Heise, Mark;
Velkoska, Elena;
Fellstrom, Bengt;
Charytan, David M;
... Wolf, Myles; + view all
(2024)
Author Correction: IL-6 inhibition with clazakizumab in patients receiving maintenance dialysis: a randomized phase 2b trial.
Nature Medicine
10.1038/s41591-024-03156-7.
(In press).
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Correa-Rotter, Ricardo;
Wheeler, David C;
McEwan, Phil;
(2024)
The Broader Effects of Delayed Progression to End-Stage Kidney Disease: Delaying the Inevitable or a Meaningful Change?
Advances in Therapy
10.1007/s12325-024-02950-6.
(In press).
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Fishbane, Steven;
Carrero, Juan-Jesus;
Kumar, Supriya;
Kanda, Eiichiro;
Hedman, Katarina;
Ofori-Asenso, Richard;
Kashihara, Naoki;
... Pecoits-Filho, Roberto; + view all
(2024)
Hyperkalemia Burden and Treatment Pathways in Patients with CKD: Findings From the DISCOVER CKD Retrospective Cohort.
Kidney360
, 5
(7)
pp. 974-986.
10.34067/KID.0000000000000468.
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Fletcher, Robert A;
Herrington, William G;
Agarwal, Rajiv;
Mayne, Kaitlin J;
Arnott, Clare;
Jardine, Meg J;
Mahaffey, Kenneth W;
... Neuen, Brendon L; + view all
(2024)
Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Cause-Specific Cardiovascular Death in Patients with CKD: A Meta-Analysis of CKD Progression Trials.
Clinical Journal of the American Society of Nephrology
, 19
(9)
pp. 1180-1182.
10.2215/CJN.0000000000000470.
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Gansevoort, Ron T;
Wheeler, David C;
Martínez Debén, Francisco;
Speeckaert, Marijn;
Thomas, Dirk;
Berger, Mario;
Klein, Stefan;
... Schmieder, Roland E; + view all
(2024)
The soluble guanylate cyclase activator runcaciguat significantly improves albuminuria in patients with chronic kidney disease: a randomized placebo-controlled clinical trial.
Nephrology Dialysis Transplantation
10.1093/ndt/gfae261.
(In press).
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Ha, Jeffrey T;
Hiremath, Swapnil;
Jun, Min;
Green, Suetonia C;
Wheeler, David C;
Coyne, Daniel W;
Perkovic, Vlado;
(2024)
Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors in Kidney Disease.
NEJM Evidence
, 3
(9)
pp. 1-12.
10.1056/EVIDoa2300189.
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Habte-Asres, Hellena Hailu;
Hou, Chuyou;
Forbes, Angus;
Wheeler, David C;
(2024)
Organisational initiatives to improve care in the prevention and management of cardiometabolic conditions: A scoping review.
Nutrition, Metabolism and Cardiovascular Diseases
, 34
(12)
pp. 2630-2641.
10.1016/j.numecd.2024.09.004.
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Habte-Asres, Hellena Hailu;
Jiang, Yutong;
Rosenthal, Miranda;
Wheeler, David Collins;
(2024)
Burden of impaired awareness of hypoglycemia in people with diabetes undergoing hemodialysis.
BMJ Open Diabetes Research & Care
, 12
(1)
, Article e003730. 10.1136/bmjdrc-2023-003730.
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Heerspink, Hiddo;
Nolan, Stephen;
Carrero, Juan-Jesus;
Arnold, Matthew;
Pecoits-Filho, Roberto;
Sanchez, Juan Jose Garcia;
Wittbrodt, Eric;
... Wheeler, David C; + view all
(2024)
Clinical Outcomes in Patients with CKD and Rapid or Non-rapid eGFR Decline: A Report from the DISCOVER CKD Retrospective Cohort.
Advances in Therapy
, 41
(8)
pp. 3264-3277.
10.1007/s12325-024-02913-x.
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Heerspink, Hiddo Jl;
Provenzano, Michele;
Vart, Priya;
Jongs, Niels;
Correa-Rotter, Ricardo;
Rossing, Peter;
Mark, Patrick B;
... Chertow, Glenn M; + view all
(2024)
Dapagliflozin and Blood Pressure in Patients with Chronic Kidney Disease and Albuminuria.
American Heart Journal
, 270
pp. 125-135.
10.1016/j.ahj.2024.02.006.
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Kotwal, Sradha S;
Perkovic, Vlado;
Jardine, Meg J;
Kim, Dana;
Shah, Nasir A;
Lin, Enmoore;
Coggan, Sarah;
... GKPTN and CAPTIVATE Investigators; + view all
(2024)
The Global Kidney Patient Trials Network and the CAPTIVATE Platform Clinical Trial Design: A Trial Protocol.
Jama Network Open
, 7
(12)
, Article e2449998. 10.1001/jamanetworkopen.2024.49998.
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Lucas, Bethany J;
Cockwell, Paul;
Fraser, Simon DS;
Kalra, Philip A;
Wheeler, David C;
Taal, Maarten W;
(2024)
Associations With Baseline Blood Pressure Control in NURTuRE-CKD.
Kidney International Reports
, 9
(5)
pp. 1508-1512.
10.1016/j.ekir.2024.02.013.
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Matus Gonzalez, Andrea;
Evangelidis, Nicole;
Howell, Martin;
Jaure, Allison;
Sautenet, Benedicte;
Madero, Magdalena;
Ashuntantang, Gloria;
... SONG-CKD, Investigators; + view all
(2024)
Outcomes for clinical trials involving adults with chronic kidney disease: a multinational Delphi survey involving patients, caregivers, and health professionals.
Nephrology Dialysis Transplantation
, 39
(8)
pp. 1310-1321.
10.1093/ndt/gfae010.
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McEwan, P;
Hafner, M;
Jha, V;
Correa-Rotter, R;
Chernin, G;
De Nicola, L;
Villanueva, R;
... Garcia Sanchez, JJ; + view all
(2024)
Correction.
[Corrigendum].
Journal of Medical Economics
, 27
(1)
pp. 165-166.
10.1080/13696998.2024.2305006.
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McEwan, Phil;
Davis, Jason A;
Gabb, Peter D;
Wheeler, David C;
Rossing, Peter;
Chertow, Glenn M;
Correa-Rotter, Ricardo;
... Garcia Sanchez, Juan Jose; + view all
(2024)
Dapagliflozin in chronic kidney disease: cost-effectiveness beyond the DAPA-CKD trial.
Clinical Kidney Journal
, 17
(2)
, Article sfae025. 10.1093/ckj/sfae025.
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McEwan, Phil;
Gabb, Peter D;
Davis, Jason A;
Sanchez, Juan Jose Garcia;
Sjöström, C David;
Barone, Salvatore;
Kashioulis, Pavlos;
... Heerspink, Hiddo JL; + view all
(2024)
The long-term effects of dapagliflozin in chronic kidney disease: a time-to-event analysis.
Nephrology Dialysis Transplantation
, Article gfae106. 10.1093/ndt/gfae106.
(In press).
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Nash, Philip S;
Fandler-Hoefler, Simon;
Ambler, Gareth;
Zhang, Wenpeng;
Ozkan, Hatice;
Locatelli, Martina;
Du, Yang;
... Werring, David J; + view all
(2024)
Associations of Cerebral Small Vessel Disease and Chronic Kidney Disease in Patients With Acute Intracerebral Hemorrhage: A Cross-Sectional Study.
Neurology
, 103
(2)
, Article e209540. 10.1212/WNL.0000000000209540.
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Patel, Siddharth M;
Kang, Yu Mi;
Im, KyungAh;
Neuen, Brendon L;
Anker, Stefan D;
Bhatt, Deepak L;
Butler, Javed;
... Wiviott, Stephen D; + view all
(2024)
Sodium-Glucose Cotransporter-2 Inhibitors and Major Adverse Cardiovascular Outcomes: A SMART-C Collaborative Meta-Analysis.
Circulation
, 149
(23)
pp. 1789-1801.
10.1161/CIRCULATIONAHA.124.069568.
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Phillips, Thomas;
Harris, Scott;
Aiyegbusi, Olalekan Lee;
Lucas, Bethany;
Benavente, Melissa;
Roderick, Paul J;
Cockwell, Paul;
... Fraser, Simon DS; + view all
(2024)
Potentially modifiable factors associated with health-related quality of life among people with chronic kidney disease: baseline findings from the National Unified Renal Translational Research Enterprise CKD (NURTuRE-CKD) cohort.
Clinical Kidney Journal
, 17
(2)
, Article sfae010. 10.1093/ckj/sfae010.
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Pinter, Jule;
Smyth, Brendan;
Stuard, Stefano;
Jardine, Meg;
Wanner, Christoph;
Rossignol, Patrick;
Wheeler, David C;
... Genser, Bernd; + view all
(2024)
Impact of Dialysate and Plasma Sodium on Mortality in a Global Historical Hemodialysis Cohort.
Journal of the American Society of Nephrology
, 35
(2)
pp. 167-176.
10.1681/ASN.0000000000000262.
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Pippias, M;
Alfano, G;
Kelly, DM;
Soler, MJ;
De Chiara, L;
Olanrewaju, TO;
Arruebo, S;
... Zaidi, D; + view all
(2024)
Capacity for the management of kidney failure in the International Society of Nephrology Western Europe region: report from the 2023 ISN Global Kidney Health Atlas (ISN-GKHA).
Kidney International Supplements
, 13
(1)
pp. 136-151.
10.1016/j.kisu.2024.01.008.
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Pollock, Carol;
Carrero, Juan-Jesus;
Kanda, Eiichiro;
Ofori-Asenso, Richard;
Chen, Hungta;
Garcia Sanchez, Juan Jose;
Pentakota, Surendra;
... Wheeler, David C; + view all
(2024)
Baseline Characteristics of the DISCOVER CKD Prospective Cohort.
Advances in Therapy
10.1007/s12325-024-03028-z.
(In press).
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Seidu, Samuel;
Alabraba, Vicki;
Davies, Sarah;
Newland-Jones, Philip;
Fernando, Kevin;
Bain, Stephen C;
Diggle, Jane;
... Wilding, John PH; + view all
(2024)
SGLT2 Inhibitors – The New Standard of Care for Cardiovascular, Renal and Metabolic Protection in Type 2 Diabetes: A Narrative Review.
Diabetes Therapy
10.1007/s13300-024-01550-5.
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Stamellou, Eleni;
Saritas, Turgay;
Froissart, Marc;
Kronenberg, Florian;
Stenvinkel, Peter;
Wheeler, David C;
Eckardt, Kai-Uwe;
... Fotheringham, James; + view all
(2024)
Identifying individuals at risk of needing CKD associated medications in a European kidney disease cohort.
BMC Nephrology
, 25
, Article 60. 10.1186/s12882-024-03497-y.
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Tangri, Navdeep;
Mathur, Vandana S;
Bushinsky, David A;
Klaerner, Gerrit;
Li, Elizabeth;
Parsell, Dawn;
Stasiv, Yuri;
... Inker, Lesley A; + view all
(2024)
VALOR-CKD: A Multicenter, Randomized, Double-Blind Placebo-Controlled Trial Evaluating Veverimer in Slowing Progression of Chronic Kidney Disease in Patients with Metabolic Acidosis.
Journal of the American Society of Nephrology
, 35
(3)
pp. 311-320.
10.1681/ASN.0000000000000292.
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Wheeler, David C;
Søndergaard, Henning;
Gwynn, Cathy;
Hedman, Katarina;
Hedberg, Jonatan;
Allum, Alaster;
Chung, Hui-Lan;
... Morris, Jon; + view all
(2024)
Randomised, blinded, cross-over evaluation of the palatability of and preference for different potassium binders in participants with chronic hyperkalaemia in the USA, Canada and Europe: the APPETIZE study.
BMJ Open
, 14
(2)
, Article e074954. 10.1136/bmjopen-2023-074954.
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Young, Hannah ML;
Castle, Ellen M;
Briggs, Juliet;
Walklin, Christy;
Billany, Roseanne E;
Asgari, Elham;
Bhandari, Sunil;
... Greenwood, Sharlene A; + view all
(2024)
The development and internal pilot trial of a digital physical activity and emotional well-being intervention (Kidney BEAM) for people with chronic kidney disease.
Science Reports
, 14
(1)
, Article 700. 10.1038/s41598-023-50507-4.
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2023
Beernink, Jelle M;
Persson, Frederik;
Jongs, Niels;
Laverman, Gozewijn D;
Chertow, Glenn M;
McMurray, John JV;
Langkilde, Anna Maria;
... Heerspink, Hiddo JL; + view all
(2023)
Efficacy of Dapagliflozin by Baseline Diabetes Medications: A Prespecified Analysis From the DAPA-CKD Study.
Diabetes Care
, Article dc221514. 10.2337/dc22-1514.
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Bhandari, Sunil;
Parfrey, Patrick;
White, Claire;
Anker, Stefan D;
Farrington, Kenneth;
Ford, Ian;
Kalra, Philip A;
... PIVOTAL Investigators, Committees; + view all
(2023)
Predictors of quality of life in patients within the first year of commencing haemodialysis based on baseline data from the PIVOTAL trial and associations with the study outcomes.
Journal of Nephrology
, 36
pp. 1651-1662.
10.1007/s40620-023-01571-6.
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Charytan, David M;
Mahaffey, Kenneth W;
Jardine, Meg J;
Cannon, Christopher P;
Neal, Bruce;
Lambers Heerspink, Hiddo J;
Agarwal, Rajiv;
... Wheeler, David C; + view all
(2023)
Cardiorenal protective effects of canagliflozin in CREDENCE according to glucose lowering.
BMJ Open Diabetes Research and Care
, 11
(3)
, Article e003270. 10.1136/bmjdrc-2022-003270.
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Chertow, Glenn M;
Correa-Rotter, Ricardo;
Vart, Priya;
Jongs, Niels;
McMurray, John JV;
Rossing, Peter;
Langkilde, Anna Maria;
... DAPA‐CKD Trial Committees and Investigators; + view all
(2023)
Effects of Dapagliflozin in Chronic Kidney Disease, With and Without Other Cardiovascular Medications: DAPA-CKD Trial.
Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease
, 12
(9)
, Article e028739. 10.1161/JAHA.122.028739.
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Desai, Nihar R;
Navaneethan, Sankar D;
Nicholas, Susanne B;
Pantalone, Kevin M;
Wanner, Christoph;
Hamacher, Stefanie;
Gay, Alain;
(2023)
Design and rationale of FINE-REAL: A prospective study of finerenone in clinical practice.
Journal of Diabetes and its Complications
, 37
(4)
, Article 108411. 10.1016/j.jdiacomp.2023.108411.
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Ebert, Thomas;
Sattar, Nosheen;
Greig, Marni;
Lamina, Claudia;
Froissart, Marc;
Eckardt, Kai-Uwe;
Floege, Jürgen;
... Fotheringham, James; + view all
(2023)
Use of Analog and Human Insulin in a European Hemodialysis Cohort With Type 2 Diabetes: Associations With Mortality, Hospitalization, MACE, and Hypoglycemia.
American Journal of Kidney Diseases
10.1053/j.ajkd.2023.05.010.
(In press).
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Fletcher, Robert A;
Jongs, Niels;
Chertow, Glenn M;
McMurray, John JV;
Arnott, Clare;
Jardine, Meg J;
Mahaffey, Kenneth W;
... Neuen, Brendon L; + view all
(2023)
Effect of SGLT2 Inhibitors on Discontinuation of Renin–angiotensin System Blockade: A Joint Analysis of the CREDENCE and DAPA-CKD Trials.
Journal of the American Society of Nephrology
, 34
(12)
pp. 1965-1975.
10.1681/ASN.0000000000000248.
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Garcia Sanchez, JJ;
James, G;
Carrero, JJ;
Arnold, M;
Lam, CSP;
Pollock, C;
Chen, H;
... Pecoits-Filho, R; + view all
(2023)
Health Care Resource Utilization and Related Costs of Patients With CKD From the United States: A Report From the DISCOVER CKD Retrospective Cohort.
Kidney International Reports
, 8
(4)
pp. 785-795.
10.1016/j.ekir.2023.01.037.
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Greenwood, SA;
Oliveira, BA;
Asgari, E;
Ayis, S;
Baker, LA;
Beckley-Hoelscher, N;
Goubar, A;
... Bramham, K; + view all
(2023)
A Randomized Trial of Intravenous Iron Supplementation and Exercise on Exercise Capacity in Iron-Deficient Nonanemic Patients With CKD.
Kidney International Reports
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Evaluating the effect of a digital health intervention to enhance physical activity in people with chronic kidney disease (Kidney BEAM): a multicentre, randomised controlled trial in the UK.
The Lancet Digital Health
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Efficacy and safety of zibotentan and dapagliflozin in patients with chronic kidney disease: study design and baseline characteristics of the ZENITH-CKD trial.
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Zibotentan in combination with dapagliflozin compared with dapagliflozin in patients with chronic kidney disease (ZENITH-CKD): a multicentre, randomised, active-controlled, phase 2b, clinical trial.
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Kidney International
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The sodium-glucose cotransporter-2 inhibitor canagliflozin does not increase risk of non-genital skin and soft tissue infections in people with type 2 diabetes mellitus: A pooled post hoc analysis from the CANVAS Program and CREDENCE randomized double-blind trials.
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Dapagliflozin and Anemia in Patients with Chronic Kidney Disease.
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Novel Anemia Therapies in CKD: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
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Ferric Carboxymaltose in Iron-Deficient Patients with Hospitalized Heart Failure and Reduced Kidney Function.
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Major cardiovascular events and subsequent risk of kidney failure with replacement therapy: a CKD Prognosis Consortium study.
European Heart Journal
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Design and population of the VALOR-CKD study: a multicenter, randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of veverimer in slowing progression of chronic kidney disease in patients with metabolic acidosis.
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Translating the efficacy of dapagliflozin in chronic kidney disease to lower healthcare resource utilization and costs: a medical care cost offset analysis.
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Hypertension and small vessel disease: do the drugs work?
British Journal of Hospital Medicine
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Defining myocardial infarction in trials of people receiving hemodialysis: consensus report from the SONG-HD MI Expert Working group.
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Diabetic Medicine
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Diabetes, Obesity and Metabolism
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An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease.
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Associations with age and glomerular filtration rate in a referred population with chronic kidney disease: Methods and baseline data from a UK multicentre cohort study (NURTuRE-CKD).
Nephrology Dialysis Transplantation
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Glycemic Control and Effects of Canagliflozin in Reducing Albuminuria and eGFR: A Post Hoc Analysis of the CREDENCE Trial.
Clinical Journal of the American Society of Nephrology
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Omitted Study Rationale and Acknowledgment of Race as a Social Construct.
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Efficacy and Safety of Dapagliflozin in Patients with Chronic Kidney Disease across the Spectrum of Frailty.
The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences
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Effectiveness and Safety of Dapagliflozin for Black vs White Patients With Chronic Kidney Disease in North and South America: A Secondary Analysis of a Randomized Clinical Trial.
Jama Network Open
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The effect of a novel, digital physical activity and emotional well-being intervention on health-related quality of life in people with chronic kidney disease: trial design and baseline data from a multicentre prospective, wait-list randomised controlled trial (kidney BEAM).
BMC Nephrology
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The Role of Expert Opinion in Projecting Long-Term Survival Outcomes Beyond the Horizon of a Clinical Trial.
Advances in Therapy
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Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes. An Individual-Participant Data Meta-Analysis.
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Kidney and Cardiovascular Effects of Canagliflozin According to Age and Sex: A Post Hoc Analysis of the CREDENCE Randomized Clinical Trial.
American Journal of Kidney Diseases
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Effects of canagliflozin on cardiovascular and kidney events in patients with chronic kidney disease with and without peripheral arterial disease: Integrated analysis from the CANVAS Program and CREDENCE trial.
Diabetes, Obesity and Metabolism
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Effects of Dapagliflozin in Chronic Kidney Disease Across the Spectrum of Age and by Sex.
Journal of General Internal Medicine
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Empagliflozin and incidence of events consistent with acute kidney injury: Pooled safety analysis in >15 000 individuals.
Diabetes, Obesity and Metabolism
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Research engagement by British early-career practitioners in nephrology: a multidisciplinary survey.
BMJ Open
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Dialysis Initiation in Patients With Chronic Coronary Disease and Advanced Chronic Kidney Disease in ISCHEMIA-CKD.
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The high-volume haemodiafiltration vs high-flux haemodialysis registry trial (H4RT): a multi-centre, unblinded, randomised, parallel-group, superiority study to compare the effectiveness and cost-effectiveness of high-volume haemodiafiltration and high-flux haemodialysis in people with kidney failure on maintenance dialysis using linkage to routine healthcare databases for outcomes.
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Quételet (Body Mass) Index and Effects of Dapagliflozin in CKD.
Diabetes, Obesity and Metabolism
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Association between practice coding of chronic kidney disease (CKD) in primary care and subsequent hospitalisations and death: a cohort analysis using national audit data.
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Sodium-Glucose Cotransporter-2 Inhibitor and Glucagon-Like Peptide-1 Receptor Agonist Combination Therapy in Type 2 Diabetes: Protocol for a Kidney End Points Real-world Study (COMBi-KID Study).
JMIR Research Protocols
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New strategies to improve clinical outcomes for diabetic kidney disease.
BMC Medicine
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The effect of intravenous iron supplementation on exercise capacity in iron-deficient but not anaemic patients with chronic kidney disease: study design and baseline data for a multicentre prospective double-blind randomised controlled trial.
BMC Nephrology
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Glycaemic variability and progression of chronic kidney disease in people with diabetes and comorbid kidney disease: Retrospective cohort study.
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Effects of Dapagliflozin in People without Diabetes and with Microalbuminuria.
Clinical Journal of the American Society of Nephrology
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Canagliflozin Reduces Kidney-Related Adverse Events in Type 2 Diabetes and CKD: Findings From the Randomized CREDENCE Trial.
American Journal of Kidney Diseases
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Low Adherence to Kidney Disease: Improving Global Outcomes 2012 CKD Clinical Practice Guidelines Despite Clear Evidence of Utility.
Kidney International Reports
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Correlates and Consequences of an Acute Change in eGFR in Response to the SGLT2 Inhibitor Dapagliflozin in Patients with CKD.
Journal of the American Society of Nephrology
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Bone Mineral Density and Vascular Calcification in Children and Young Adults With CKD 4 to 5 or on Dialysis.
Kidney International Reports
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The burden of subclinical cardiovascular disease in children and young adults with chronic kidney disease and on dialysis.
Clinical Kidney Journal
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Effect of Canagliflozin on Total Cardiovascular Burden in Patients With Diabetes and Chronic Kidney Disease: A Post Hoc Analysis From the CREDENCE Trial.
Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease
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The impact of canagliflozin on the risk of neuropathy events: a post-hoc exploratory analysis of the CREDENCE trial.
Diabetes & Metabolism
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Effect of Oral Methylprednisolone on Decline in Kidney Function or Kidney Failure in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial.
Journal of the American Medical Association
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Extrapolated longer-term effects of the DAPA-CKD trial: a modelling analysis.
Nephrology Dialysis Transplantation
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Cost-Effectiveness of Dapagliflozin as a Treatment for Chronic Kidney Disease: A Health-Economic Analysis of DAPA-CKD.
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Sodium-Glucose Cotransporter 2 Inhibitors and Risk of Hyperkalemia in People With Type 2 Diabetes: A Meta-Analysis of Individual Participant Data From Randomized, Controlled Trials.
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Healthcare resource utilisation and related costs of patients with CKD from the UK: a report from the DISCOVER CKD retrospective cohort.
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The Kidney Protective Effects of the Sodium–Glucose Cotransporter-2 Inhibitor, Dapagliflozin, Are Present in Patients With CKD Treated With Mineralocorticoid Receptor Antagonists.
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Dapagliflozin and new-onset type 2 diabetes in patients with chronic kidney disease or heart failure: pooled analysis of the DAPA-CKD and DAPA-HF trials.
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Correa-Rotter, Ricardo;
Rossing, Peter;
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(2022)
Effects of Dapagliflozin on Hospitalizations in Patients With Chronic Kidney Disease : A Post Hoc Analysis of DAPA-CKD.
Annals of Internal Medicine
10.7326/M22-2115.
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Cizman, Borut;
Carroll, Kevin;
McMurray, John J;
Perkovic, Vlado;
Jha, Vivekanand;
Johansen, Kirsten L;
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(2022)
Efficacy and Safety of Daprodustat for Treatment of Anemia of Chronic Kidney Disease in Incident Dialysis Patients A Randomized Clinical Trial.
JAMA Internal Medicine
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An Analysis of Vascular Access Thrombosis Events From the Proactive IV irOn Therapy in hemodiALysis Patients Trial.
Kidney International Reports
10.1016/j.ekir.2022.05.008.
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Levin, Adeera;
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Elsäßer, Amelie;
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Safety of Empagliflozin in Patients With Type 2 Diabetes and Chronic Kidney Disease: Pooled Analysis of Placebo-Controlled Clinical Trials.
Diabetes Care
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Correa-Rotter, Ricardo;
Hou, Fan Fan;
Jongs, Niels;
Chertow, Glenn M;
Langkilde, Anna Maria;
McMurray, John JV;
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(2022)
Efficacy and Safety of Dapagliflozin in Patients With CKD Across Major Geographic Regions.
Kidney International Reports
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10.1016/j.ekir.2022.01.1060.
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Vart, Priya;
Vaduganathan, Muthiah;
Jongs, Niels;
Remuzzi, Giuseppe;
Wheeler, David C;
Hou, Fan Fan;
McCausland, Finnian;
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(2022)
Estimated Lifetime Benefit of Combined RAAS and SGLT2 Inhibitor Therapy in Patients with Albuminuric CKD without Diabetes.
Clinical Journal of the American Society of Nephrology
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10.2215/CJN.08900722.
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Vart, Priya;
Cherney, David Z;
Chertow, Glenn M;
Jongs, Niels;
Langkilde, Anna Maria;
Mann, Johannes FE;
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(2022)
Effect of dapagliflozin on kidney and cardiovascular outcomes by baseline KDIGO risk categories: a post hoc analysis of the DAPA-CKD trial.
Diabetologia
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The Place and Value of Sodium-Glucose Cotransporter 2 Inhibitors in the Evolving Treatment Paradigm for Type 2 Diabetes Mellitus: A Narrative Review.
Diabetes Therapy
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Young, Tamara K;
Toussaint, Nigel D;
Di Tanna, Gian Luca;
Arnott, Clare;
Hockham, Carinna;
Kang, Amy;
Schutte, Aletta E;
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(2022)
Risk Factors for Fracture in Patients with Coexisting Chronic Kidney Disease and Type 2 Diabetes: An Observational Analysis from the CREDENCE Trial.
Journal of Diabetes Research
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Bjornstad, P;
Greasley, PJ;
Wheeler, DC;
Chertow, GM;
Langkilde, AM;
Heerspink, HJL;
van Raalte, DH;
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The potential roles of osmotic and non-osmotic sodium handling in mediating effects of SGLT2 inhibitors on heart failure.
Journal of Cardiac Failure
10.1016/j.cardfail.2021.07.003.
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Kang, Amy;
Smyth, Brendan;
Yi, Tae Won;
Di Tanna, Gian Luca;
Pollock, Carol A;
De Zeeuw, Dick;
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(2021)
133-LB: Canagliflozin Improves Cardiovascular and Renal Outcomes across Broad Geographic Regions: Results from CREDENCE.
Presented at: 81st Scientific Sessions, Virtual.
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Chertow, GM;
Vart, P;
Jongs, N;
Toto, RD;
Gorriz, JL;
Hou, FF;
McMurray, JJV;
... DAPA-CKD Trial Committees and Investigators, .; + view all
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Effects of Dapagliflozin in Stage 4 Chronic Kidney Disease.
Journal of the American Society of Nephrology
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10.1681/ASN.2021020167.
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Oomatia, A;
Webster, AP;
Beck, S;
Ponticos, M;
Lindsey, B;
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(2021)
Epigenome-wide methylation profile of chronic kidney disease-derived arterial DNA uncovers novel pathways in disease-associated cardiovascular pathology.
Epigenetics
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10.1080/15592294.2020.1819666.
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Qureshi, AR;
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Eckardt, KU;
Wheeler, DC;
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Time-dependent lipid profile inversely associates with mortality in hemodialysis patients – independent of inflammation/malnutrition.
Journal of Internal Medicine
10.1111/joim.13291.
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Price, AM;
Mehta, S;
Hiemstra, TF;
Kaur, A;
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Effects of Spironolactone and Chlorthalidone on Cardiovascular Structure and Function in Chronic Kidney Disease: A Randomized, Open-Label Trial.
Clinical Journal of the American Society of Nephrology
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10.2215/CJN.01930221.
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Standardised Outcomes in Nephrology - Chronic Kidney Disease (SONG-CKD): a protocol for establishing a core outcome set for adults with chronic kidney disease who do not require kidney replacement therapy.
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Perspectives on blood pressure by patients on haemo- and peritoneal dialysis.
Nephrology
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10.1111/nep.13775.
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The International Society of Nephrology Advancing Clinical Trials (ISN-ACT) Network: current activities and future goals.
Kidney International
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10.1016/j.kint.2020.10.048.
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Survival on four compared with three times per week haemodialysis in high ultrafiltration patients: an observational study.
Clinical Kidney Journal
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10.1093/ckj/sfaa250.
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The PrEscription of intraDialytic exercise to improve quAlity of Life in patients with chronic kidney disease trial: study design and baseline data for a multicentre randomized controlled trial.
Clinical Kidney Journal
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Randomized Trial—PrEscription of intraDialytic exercise to improve quAlity of Life in Patients Receiving Hemodialysis.
Kidney International Reports
10.1016/j.ekir.2021.05.034.
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Exercise programme to improve quality of life for patients with end-stage kidney disease receiving haemodialysis: the PEDAL RCT.
Health Technology Assessment
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(2021)
A pre-specified analysis of the Dapagliflozin and Prevention of Adverse Outcomes in Chronic Kidney Disease (DAPA-CKD) randomized controlled trial on the incidence of abrupt declines in kidney function.
Kidney International
10.1016/j.kint.2021.09.005.
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(2021)
Effect of dapagliflozin on the rate of decline in kidney function in patients with chronic kidney disease with and without type 2 diabetes: a prespecified analysis from the DAPA-CKD trial.
Lancet Diabetes Endocrinol
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Dapagliflozin in Patients with Chronic Kidney Disease.
New England Journal of Medicine
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McMurray, JJV;
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(2021)
Effects of dapagliflozin on mortality in patients with chronic kidney disease: a pre-specified analysis from the DAPA-CKD randomized controlled trial.
European Heart Journal
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10.1093/eurheartj/ehab094.
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Understanding and Overcoming the Challenges Related to Cardiovascular Trials Involving Patients with Kidney Disease.
Clinical Journal of the American Society of Nephrology
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Kidney, Cardiovascular, and Safety Outcomes of Canagliflozin according to Baseline Albuminuria: A CREDENCE Secondary Analysis.
Clinical Journal of the American Society of Nephrology
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Heart Failure Hospitalization in Adults Receiving Hemodialysis and the Effect of Intravenous Iron Therapy.
JACC: Heart Failure
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10.1016/j.jchf.2021.04.005.
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Correa-Rotter, R;
Rossing, P;
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(2021)
Effect of dapagliflozin on urinary albumin excretion in patients with chronic kidney disease with and without type 2 diabetes: a prespecified analysis from the DAPA-CKD trial.
Lancet Diabetes and Endocrinology
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10.1016/S2213-8587(21)00243-6.
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Crabtree, NJ;
Ferro, CJ;
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Mitsioni, A;
Biassoni, L;
Kaur, A;
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(2021)
Routine serum biomarkers, but not dual-energy X-ray absorptiometry, correlate with cortical bone mineral density in children and young adults with chronic kidney disease.
Nephrology Dialysis Transplantation
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10.1093/ndt/gfaa199.
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Kang, Amy;
Xia, Chao;
Arnott, Clare;
Di Tanna, Gian Luca;
Krishnan, Arun V;
Pollock, Carol A;
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(2021)
131-LB: The Impact of Canagliflozin on the Risk of Neuropathy Events: Results from the CREDENCE Trial.
Presented at: 81st Scientific Sessions, Virtual.
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Mark, Patrick B;
Jhund, Pardeep S;
Walters, Matthew R;
Petrie, Mark C;
Power, Albert;
White, Claire;
Robertson, Michele;
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(2021)
Stroke in Hemodialysis Patients Randomized to Different Intravenous Iron Strategies: A Prespecified Analysis from the PIVOTAL Trial.
Kidney360
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10.34067/KID.0004272021.
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Stefánsson, BV;
Jongs, N;
Postmus, D;
Correa-Rotter, R;
Chertow, GM;
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Effects of Dapagliflozin in Patients With Kidney Disease, With and Without Heart Failure.
JACC: Heart Failure
10.1016/j.jchf.2021.06.017.
(In press).
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McMurray, JJV;
Wheeler, DC;
Stefánsson, BV;
Jongs, N;
Postmus, D;
Correa-Rotter, R;
Chertow, GM;
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Effect of Dapagliflozin on Clinical Outcomes in Patients with Chronic Kidney Disease, With and Without Cardiovascular Disease.
Circulation
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10.1161/CIRCULATIONAHA.120.051675.
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Relative and Absolute Risk Reductions in Cardiovascular and Kidney Outcomes With Canagliflozin Across KDIGO Risk Categories: Findings From the CANVAS Program.
American Journal of Kidney Diseases
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Bakris, G;
Cannon, CP;
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(2021)
Effects of canagliflozin on serum potassium in people with diabetes and chronic kidney disease: the CREDENCE trial.
European Heart Journal
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10.1093/eurheartj/ehab497.
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James, G;
Carrero, JJ;
Wittbrodt, E;
Fishbane, S;
Sultan, AA;
Heerspink, HJL;
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Methods and rationale of the DISCOVER CKD global observational study.
Clinical Kidney Journal
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10.1093/ckj/sfab046.
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Davies, R;
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The ASCEND-ND trial: Study design and participant characteristics.
Nephrology Dialysis Transplantation
10.1093/ndt/gfab318.
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Persson, Frederik;
Rossing, Peter;
Vart, Priya;
Chertow, Glenn M;
Hou, Fan Fan;
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Correa-Rotter, Ricardo;
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(2021)
317-OR: Efficacy and Safety of Dapagliflozin by Glycemic Status in the DAPA-CKD Trial.
Presented at: 81st Virtual Scientific Sessions, Virtual.
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Persson, F;
Rossing, P;
Vart, P;
Chertow, GM;
Hou, FF;
Jongs, N;
McMurray, JJV;
... DAPA-CKD Trial Committees and Investigators; + view all
(2021)
Efficacy and Safety of Dapagliflozin by Baseline Glycemic Status: A Prespecified Analysis From the DAPA-CKD Trial.
Diabetes Care
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Petrie, MC;
Jhund, PS;
Connolly, E;
Mark, PB;
MacDonald, MR;
Robertson, M;
Anker, SD;
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(2021)
High-dose intravenous iron reduces myocardial infarction in patients on haemodialysis.
Cardiovascular Research
10.1093/cvr/cvab317.
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Vart, Priya;
Chertow, Glenn M;
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Correa-Rotter, Ricardo;
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(2021)
130-LB: Dapagliflozin and the Incidence of Type 2 Diabetes in Patients with Chronic Kidney Disease.
Presented at: 81st Scientific Sessions, Virtual.
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Sarraju, A;
Li, J;
Cannon, CP;
Chang, TI;
Agarwal, R;
Bakris, G;
Charytan, DM;
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(2021)
Effects of Canagliflozin on Cardiovascular, Renal, and Safety Outcomes in Participants With Type 2 Diabetes and Chronic Kidney Disease According to History of Heart Failure: Results From the CREDENCE Trial.
American Heart Journal
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10.1016/j.ahj.2020.12.008.
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McMurray, JJ;
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Jha, V;
Johansen, KL;
Lopes, RD;
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Daprodustat for the Treatment of Anemia in Patients Not Undergoing Dialysis.
The New England Journal of Medicine
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10.1056/NEJMoa2113380.
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Johansen, KL;
Lopes, RD;
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Daprodustat for the Treatment of Anemia in Patients Undergoing Dialysis.
New England Journal of Medicine
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10.1056/NEJMoa2113379.
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Study design and baseline characteristics of patients on dialysis in the ASCEND-D trial.
Nephrology Dialysis Transplantation
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Sjöström, CD;
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Data from a pooled post hoc analysis of 14 placebo-controlled, dapagliflozin treatment studies in patients with type 2 diabetes with and without anemia at baseline.
Data Brief
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Chlorthalidone in Advanced Chronic Kidney Disease - Have We Missed a Trick?
New England Journal of Medicine
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10.1056/NEJMe2118149.
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Hou, FF;
Langkilde, AM;
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(2021)
Safety and efficacy of dapagliflozin in patients with focal segmental glomerulosclerosis: A prespecified analysis of the DAPA-CKD trial.
Nephrology Dialysis Transplantation
10.1093/ndt/gfab335.
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Chertow, GM;
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Hou, FF;
McMurray, JJ;
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(2021)
Effects of dapagliflozin on major adverse kidney and cardiovascular events in patients with diabetic and non-diabetic chronic kidney disease: a prespecified analysis from the DAPA-CKD trial.
Lancet Diabetes & Endocrinology
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Greene, T;
Hou, FF;
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(2021)
A pre-specified analysis of the DAPA-CKD trial demonstrates the effects of dapagliflozin on major adverse kidney events in patients with IgA nephropathy.
Kidney International
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The Therapeutic Evaluation of Steroids in IgA Nephropathy Global (TESTING) Study: Trial Design and Baseline Characteristics.
American Journal of Nephrology
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Ye, N;
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Bakris, G;
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(2021)
Blood Pressure Effects of Canagliflozin and Clinical Outcomes in Type 2 Diabetes and Chronic Kidney Disease: Insights from the CREDENCE Trial.
Circulation
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Kang, Amy;
Cardoza, Kathryn;
Di Tanna, Gian Luca;
Arnott, Clare;
Pollock, Carol A;
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129-LB: Kidney and Cardiovascular Effects of Canagliflozin According to Age and Sex in the CREDENCE Trial.
Presented at: 81st Scientific Sessions, Virtual.
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Mahaffey, KW;
Agarwal, R;
Cannon, CP;
Capuano, G;
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Effects of Canagliflozin in Patients with Baseline eGFR <30 ml/min per 1.73 m²: Subgroup Analysis of the Randomized CREDENCE Trial.
Clinical Journal of the American Society of Nephrology
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Evaluating the Effects of Canagliflozin on Cardiovascular and Renal Events in Patients with Type 2 Diabetes and Chronic Kidney Disease According to Baseline HbA1c, Including Those with HbA1c <7%: Results From the CREDENCE Trial.
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