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Number of items: 110.
A
Abbosh, Christopher;
Frankell, Alexander M;
Harrison, Thomas;
Kisistok, Judit;
Garnett, Aaron;
Johnson, Laura;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2023)
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Nature
, 616
(7957)
pp. 553-562.
10.1038/s41586-023-05776-4.
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Al Bakir, Maise;
Huebner, Ariana;
Martínez-Ruiz, Carlos;
Grigoriadis, Kristiana;
Watkins, Thomas BK;
Pich, Oriol;
Moore, David A;
... Swanton, Charles; + view all
(2023)
The evolution of non-small cell lung cancer metastases in TRACERx.
Nature
10.1038/s41586-023-05729-x.
(In press).
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Arellano-Ballestero, Helena;
Sabry, May;
Lowdell, Mark W;
(2023)
A Killer Disarmed: Natural Killer Cell Impairment in Myelodysplastic Syndrome.
Cells
, 12
(4)
, Article 633. 10.3390/cells12040633.
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B
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Barker, Dominic J;
Maccari, Giuseppe;
Georgiou, Xenia;
Cooper, Michael A;
Flicek, Paul;
Robinson, James;
Marsh, Steven GE;
(2023)
The IPD-IMGT/HLA Database.
Nucleic Acids Research
, 51
(D1)
D1053-D1060.
10.1093/nar/gkac1011.
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Barnes, Josephine L;
Yoshida, Masahiro;
He, Peng;
Worlock, Kaylee B;
Lindeboom, Rik GH;
Suo, Chenqu;
Pett, J Patrick;
... Nikolić, Marko Z; + view all
(2023)
Early human lung immune cell development and its role in epithelial cell fate.
Science Immunology
, 8
(90)
, Article eadf9988. 10.1126/sciimmunol.adf9988.
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Bennett, Clare L;
Perona-Wright, Georgia;
(2023)
Metabolic adaption of mucosal macrophages: Is metabolism a driver of persistence across tissues?
Mucosal Immunology
10.1016/j.mucimm.2023.06.006.
(In press).
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Bichet, DG;
Hopkin, RJ;
Aguiar, P;
Allam, SR;
Chien, YH;
Giugliani, R;
Kallish, S;
... Hughes, DA; + view all
(2023)
Consensus recommendations for the treatment and management of patients with Fabry disease on migalastat: a modified Delphi study.
Frontiers in Medicine
, 10
, Article 1220637. 10.3389/fmed.2023.1220637.
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Bowcock, Stella;
Atkin, Catherine;
Iqbal, Gulnaz;
Pratt, Guy;
Yong, Kwee;
Neal, Richard D;
Planche, Tim;
... Drayson, Mark T; + view all
(2023)
Presenting Symptoms in Newly Diagnosed Myeloma, Relation to Organ Damage, and Implications for Symptom-Directed Screening: A Secondary Analysis from the Tackling Early Morbidity and Mortality in Myeloma (TEAMM) Trial.
Cancers
, 15
(13)
, Article 3337. 10.3390/cancers15133337.
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Burlina, A;
Brand, E;
Hughes, D;
Kantola, I;
Krӓmer, J;
Nowak, A;
Tøndel, C;
... Spada, M; + view all
(2023)
An expert consensus on the recommendations for the use of biomarkers in Fabry disease.
Molecular Genetics and Metabolism
, 139
(2)
, Article 107585. 10.1016/j.ymgme.2023.107585.
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C
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Calvisi, DF;
Boulter, L;
Vaquero, J;
Saborowski, A;
Fabris, L;
Rodrigues, PM;
Coulouarn, C;
... Saito, Y; + view all
(2023)
Criteria for preclinical models of cholangiocarcinoma: scientific and medical relevance.
Nature Reviews Gastroenterology and Hepatology
, 20
pp. 462-480.
10.1038/s41575-022-00739-y.
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Cappellini, MD;
Taher, AT;
Piga, A;
Shah, F;
Voskaridou, E;
Viprakasit, V;
Porter, JB;
... Oliva, EN; + view all
(2023)
Health-related quality of life in patients with β-thalassemia: Data from the phase 3 BELIEVE trial of luspatercept.
European Journal of Haematology
, 111
(1)
pp. 113-124.
10.1111/ejh.13975.
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Castillo, Simon P;
Galvez-Cancino, Felipe;
Liu, Jiali;
Pollard, Steven M;
Quezada, Sergio A;
Yuan, Yinyin;
(2023)
The tumour ecology of quiescence: Niches across scales of complexity.
Seminars in Cancer Biology
, 92
pp. 139-149.
10.1016/j.semcancer.2023.04.004.
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Cheminant, Morgane;
Fox, Thomas A;
Alligon, Mickael;
Bouaziz, Olivier;
Neven, Bénédicte;
Moshous, Despina;
Blanche, Stephane;
... Suarez, Felipe; + view all
(2023)
Allogeneic stem cell transplantation compared to conservative management in adults with inborn errors of immunity.
Blood
, 141
(1)
pp. 60-71.
10.1182/blood.2022015482.
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Cheok, Kathleen PL;
Kirkwood, Amy A;
Creasey, Thomas;
Tholouli, Eleni;
Chaganti, Sridhar;
Mathew, Amrith;
Dulobdas, Vaishali;
... Roddie, Claire; + view all
(2023)
Improved COVID-19 outcomes in CAR-T patients in the age of vaccination and preemptive pharmacotherapeutics.
Leukemia & Lymphoma
10.1080/10428194.2023.2248329.
(In press).
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Chighizola, Cecilia B;
Pregnolato, Francesca;
Andrade, Danieli;
Tektonidou, Maria;
Pengo, Vittorio;
Ruiz-Irastorza, Guillermo;
Belmont, H Michael;
... AntiPhospholipid Syndrome Alliance For Clinical Trials and Inter, .; + view all
(2023)
Fluctuation of Anti-Domain 1 and Anti-Β2 Glycoprotein I Antibody Titers Over Time in Patients with Persistently Positive Antiphospholipid Antibodies.
Arthritis & Rheumatology
, 75
(6)
pp. 984-995.
10.1002/art.42459.
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Chowdary, P;
Agarwal, B;
Peralta, MR;
Bhagani, S;
Lee, S;
Goldring, J;
Lipman, M;
... Gomez, K; + view all
(2023)
Nebulized Recombinant Tissue Plasminogen Activator (rt-PA) for Acute COVID-19-Induced Respiratory Failure: An Exploratory Proof-of-Concept Trial.
Journal of Clinical Medicine
, 12
(18)
, Article 5848. 10.3390/jcm12185848.
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Cohen, Hannah;
Werring, David J;
Chandretheva, Arvind;
Mittal, Prabal;
Devreese, Katrien MJ;
Isenberg, David A;
ISTH SSC LA/aPL Subcommittee Study Group;
(2023)
Survey on antiphospholipid syndrome diagnosis and antithrombotic treatment in patients with ischemic stroke, other brain ischemic injury, or arterial thromboembolism in other sites: communication from ISTH SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies.
Journal of Thrombosis and Haemostasis
, 21
(10)
pp. 2963-2976.
10.1016/j.jtha.2023.06.020.
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Costoya, Cristobal Javier Costoya;
(2023)
Role of FcγRs in anti-OX40 based immunotherapies.
Doctoral thesis (Ph.D), UCL (University College London).
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Cowan, Annie;
Ferrari, Federico;
Freeman, Samuel S;
Redd, Robert;
El-Khoury, Habib;
Perry, Jacqueline;
Patel, Vidhi;
... Ghobrial, Irene M; + view all
(2023)
Personalised progression prediction in patients with monoclonal gammopathy of undetermined significance or smouldering multiple myeloma (PANGEA): a retrospective, multicohort study.
The Lancet Haematology
, 10
(3)
e203-e212.
10.1016/S2352-3026(22)00386-6.
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Cuadrado Collados, Maria Del Mar;
(2023)
Strategies to Improve Haematological Reconstitution Post-Allogeneic Haematopoietic Stem Cell Transplantation.
Doctoral thesis (M.D(Res)), UCL (University College London).
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D
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Dalmia, S;
Sharma, R;
Ramaswami, U;
Hughes, D;
Jahnke, N;
Cole, D;
Smith, S;
(2023)
Enzyme replacement therapy for late-onset Pompe disease.
Cochrane Database of Systematic Reviews
, 2023
(12)
, Article CD012993. 10.1002/14651858.CD012993.pub2.
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de Botton, Stephane;
Fenaux, Pierre;
Yee, Karen;
Recher, Christian;
Wei, Andrew H;
Montesinos, Pau;
Taussig, David C;
... Cortes, Jorge; + view all
(2023)
Olutasidenib (FT-2102) induces durable complete remissions in patients with relapsed or refractory IDH1-mutated AML.
Blood Advances
, 7
(13)
pp. 3117-3127.
10.1182/bloodadvances.2022009411.
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Ding, Wen Y;
Kuzmuk, Valeryia;
Hunter, Sarah;
Lay, Abigail;
Hayes, Bryony;
Beesley, Matthew;
Rollason, Ruth;
... Saleem, Moin A; + view all
(2023)
Adeno-associated virus gene therapy prevents progression of kidney disease in genetic models of nephrotic syndrome.
Science Translational Medicine
, 15
(708)
, Article eabc8226. 10.1126/scitranslmed.abc8226.
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Dumontet, Charles;
Demangel, Delphine;
Galia, Perrine;
Karlin, Lionel;
Roche, Laurent;
Fauvernier, Mathieu;
Golfier, Camille;
... Garderet, Laurent; + view all
(2023)
Clinical characteristics and outcome of 318 families with familial monoclonal gammopathy: A multicenter Intergroupe Francophone du Myélome study.
American Journal of Hematology
, 98
(2)
pp. 264-271.
10.1002/ajh.26785.
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E
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El-Galaly, Tarec Christoffer;
Gaidzik, Verena I;
Gaman, Mihnea-Alexandru;
Antic, Darko;
Okosun, Jessica;
Copland, Mhairi;
Sexl, Veronika;
... Grønbæk, Kirsten; + view all
(2023)
A Lack of Diversity, Equity, and Inclusion in Clinical Research Has Direct Impact on Patient Care.
Hemasphere
, 7
(3)
, Article e842. 10.1097/HS9.0000000000000842.
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F
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Fang, Z;
Corbizi Fattori, G;
McKerrell, T;
Boucher, RH;
Jackson, A;
Fletcher, RS;
Forte, D;
... Méndez-Ferrer, S; + view all
(2023)
Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis.
Nature Communications
, 14
, Article 7725. 10.1038/s41467-023-43175-5.
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Foley, JH;
Shehu, E;
Riddell, A;
Gray, E;
Goodale, A;
Yu, IM;
Verhoef, D;
... Nathwani, AC; + view all
(2023)
Differences in wild-type– and R338L-tenase complex formation are at the root of R338L-factor IX assay discrepancies.
Blood Advances
, 7
(3)
pp. 458-467.
10.1182/bloodadvances.2022007435.
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Frankell, AM;
Dietzen, M;
Al Bakir, M;
Lim, EL;
Karasaki, T;
Ward, S;
Veeriah, S;
... Gilbert, K; + view all
(2023)
The evolution of lung cancer and impact of subclonal selection in TRACERx.
Nature
, 616
pp. 525-533.
10.1038/s41586-023-05783-5.
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Freeman, SD;
Thomas, A;
Thomas, I;
Hills, RK;
Vyas, P;
Gilkes, A;
Metzner, M;
... Russell, NH; + view all
(2023)
Fractionated vs single-dose gemtuzumab ozogamicin with determinants of benefit in older patients with AML: the UK NCRI AML18 trial.
Blood
, 142
(20)
pp. 1697-1707.
10.1182/blood.2023020630.
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G
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Galvez-Cancino, Felipe;
Simpson, Alexander P;
Costoya, Cristobal;
Matos, Ignacio;
Qian, Danwen;
Peggs, Karl S;
Litchfield, Kevin;
(2023)
Fcγ receptors and immunomodulatory antibodies in cancer.
Nature Reviews Cancer
, 24
(1)
pp. 51-71.
10.1038/s41568-023-00637-8.
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Garbowski, Maciej W;
Cabantchik, Ioav;
Hershko, Chaim;
Hider, Robert;
Porter, John B;
(2023)
The clinical relevance of detectable plasma iron species in iron overload states and subsequent to intravenous iron-carbohydrate administration.
American Journal of Hematology
, 98
(3)
pp. 533-540.
10.1002/ajh.26819.
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Garbowski, MW;
Ugidos, M;
Risueño, A;
Shetty, JK;
Schwickart, M;
Hermine, O;
Porter, JB;
... Vodala, S; + view all
(2023)
Luspatercept stimulates erythropoiesis, increases iron utilization, and redistributes body iron in transfusion-dependent thalassemia.
American Journal of Hematology
10.1002/ajh.27102.
(In press).
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Garcia-Diaz, Claudia;
Pöysti, Anni;
Mereu, Elisabetta;
Clements, Melanie P;
Brooks, Lucy J;
Galvez-Cancino, Felipe;
Castillo, Simon P;
... Parrinello, Simona; + view all
(2023)
Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin.
Cell Reports
, 42
(5)
, Article 112472. 10.1016/j.celrep.2023.112472.
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Gardner, Oliver FW;
Agabalyan, Natacha;
Weil, Ben;
Ali, Mohammed HI;
Lowdell, Mark W;
Bulstrode, Neil W;
Ferretti, Patrizia;
(2023)
Human platelet lysate enhances proliferation but not chondrogenic differentiation of pediatric mesenchymal progenitors.
Cytotherapy
, 25
(3)
pp. 286-297.
10.1016/j.jcyt.2022.11.007.
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Ghorani, Ehsan;
Swanton, Charles;
Quezada, Sergio A;
(2023)
Cancer cell-intrinsic mechanisms driving acquired immune tolerance.
Immunity
, 56
(10)
pp. 2270-2295.
10.1016/j.immuni.2023.09.004.
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Gkrouzman, Elena;
Willis, Rohan;
Andrade, Danieli;
Tektonidou, Maria G;
Pengo, Vittorio;
Ruiz-Irastorza, Guillermo;
Belmont, H Michael;
... APS, ACTION; + view all
(2023)
Associations Among Antiphospholipid Antibody Types, Isotypes, and Titers: An AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) Study.
Laboratory Investigation
, 103
(6)
, Article 100147. 10.1016/j.labinv.2023.100147.
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Goyal, Lipika;
Meric-Bernstam, Funda;
Hollebecque, Antoine;
Valle, Juan W;
Morizane, Chigusa;
Karasic, Thomas B;
Abrams, Thomas A;
... FOENIX-CCA2 Study Investigators; + view all
(2023)
Futibatinib for FGFR2-Rearranged Intrahepatic Cholangiocarcinoma.
New England Journal of Medicine
, 388
(3)
pp. 228-239.
10.1056/NEJMoa2206834.
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Gregucci, Fabiana;
Spada, Sheila;
Barcellos-Hoff, Mary Helen;
Bhardwaj, Nina;
Hak, Charleen Chan Wah;
Fiorentino, Alba;
Guha, Chandan;
... Formenti, Silvia C; + view all
(2023)
Updates on radiotherapy-immunotherapy combinations: Proceedings of 6(th) annual ImmunoRad conference.
OncoImmunology
, 12
(1)
, Article 2222560. 10.1080/2162402X.2023.2222560.
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Gupta, Shweta;
Kaffo, Eleanor;
Baker, Robert;
Nacheva, Elisabeth;
O'Nions, Jenny;
Wilson, Andrew J;
Gupta, Rajeev;
(2023)
The Use of Targeted RNA- Sequencing Assay in the Diagnostic Evaluation of Acute Myeloid Leukaemia(AML).
Presented at: 65th ASH Annual Meeting, San Diego, CA, USA.
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H
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Hagos, Yeman B;
Lecat, Catherine SY;
Patel, Dominic;
Mikolajczak, Anna;
Castillo, Simon P;
Lyon, Emma J;
Foster, Kane;
... Yuan, Yinyin; + view all
(2023)
Deep learning enables spatial mapping of the mosaic microenvironment of myeloma bone marrow trephine biopsies.
Cancer Research
10.1158/0008-5472.can-22-2654.
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Harding, James J;
Fan, Jia;
Oh, Do-Youn;
Choi, Hye Jin;
Kim, Jin Won;
Chang, Heung-Moon;
Bao, Lequn;
... HERIZON-BTC-01 study group; + view all
(2023)
Zanidatamab for HER2-amplified, unresectable, locally advanced or metastatic biliary tract cancer (HERIZON-BTC-01): a multicentre, single-arm, phase 2b study.
The Lancet Oncology
, 24
(7)
pp. 772-782.
10.1016/S1470-2045(23)00242-5.
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Howell, Rowan;
Davies, James;
Clarke, Matthew A;
Appios, Anna;
Mesquita, Inês;
Jayal, Yashoda;
Ringham-Terry, Ben;
... Bennett, Clare L; + view all
(2023)
Localized immune surveillance of primary melanoma in the skin deciphered through executable modeling.
Science Advances
, 9
(15)
, Article eadd1992. 10.1126/sciadv.add1992.
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Hubig, L;
Sussex, AK;
MacCulloch, A;
Hughes, D;
Graham, R;
Morris, L;
Raza, S;
... Gallop, K; + view all
(2023)
Quality of Life with Late-Onset Pompe Disease: Qualitative Interviews and General Public Utility Estimation in the United Kingdom.
Journal of Health Economics and Outcomes Research
, 10
(1)
pp. 41-50.
10.36469/001c.68157.
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Huerga Encabo, H;
Aramburu, IV;
Garcia-Albornoz, M;
Piganeau, M;
Wood, H;
Song, A;
Ferrelli, A;
... Bonnet, D; + view all
(2023)
Loss of TET2 in human hematopoietic stem cells alters the development and function of neutrophils.
Cell Stem Cell
, 30
(6)
781-799.e9.
10.1016/j.stem.2023.05.004.
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Hughes, D;
Gonzalez, D;
Maegawa, G;
Bernat, JA;
Holida, M;
Giraldo, P;
Atta, MG;
... Goker-Alpan, O; + view all
(2023)
Long-term safety and efficacy of pegunigalsidase alfa: A multicenter 6-year study in adult patients with Fabry disease.
Genetics in Medicine
, 25
(12)
, Article 100968. 10.1016/j.gim.2023.100968.
(In press).
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Hughes, D;
Lenny, A;
Shah, K;
Longworth, L;
Devercelli, G;
Ayodele, O;
(2023)
Estimation of Health State Utility Values in Fabry Disease Using Vignette Development and Valuation.
Journal of Health Economics and Outcomes Research
, 10
(1)
pp. 80-88.
10.36469/001c.71344.
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Hughes, DA;
Deegan, P;
Giraldo, P;
Göker-Alpan, Ö;
Lau, H;
Lukina, E;
Revel-Vilk, S;
... Zimran, A; + view all
(2023)
Reply to Mistry et al. The Two Substrate Reduction Therapies for Type 1 Gaucher Disease Are Not Equivalent. Comment on “Hughes et al. Switching between Enzyme Replacement Therapies and Substrate Reduction Therapies in Patients with Gaucher Disease: Data from the Gaucher Outcome Survey (GOS). J. Clin. Med. 2022, 11, 5158”.
Journal of Clinical Medicine
, 12
(12)
, Article 4017. 10.3390/jcm12124017.
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Hughes, Derralynn A;
Ferrante, Francesca;
(2023)
GALILEO-1: a Phase I/II safety and efficacy study of FLT201 gene therapy for Gaucher disease type 1.
Future Rare Diseases
10.2217/frd-2022-0019.
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I
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Iland, Harry J;
Russell, Nigel;
Dillon, Richard;
Schuh, Andre C;
Tedjaseputra, Aditya;
Wei, Andrew;
Khwaja, Asim;
... Tholoui, Eleni; + view all
(2023)
Characteristics and outcomes of patients with acute promyelocytic leukemia and extreme hyperleukocytosis at presentation.
Blood Advances
, 7
(11)
pp. 2580-2585.
10.1182/bloodadvances.2022007126.
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Iskander, Deena;
Roy, Noémi BA;
Payne, Elspeth;
Drasar, Emma;
Hennessy, Kelly;
Harrington, Yvonne;
Christodoulidou, Chrysi;
... De la Fuente, Josu; + view all
(2023)
Diamond-Blackfan anemia in adults: In pursuit of a common approach for a rare disease.
Blood Reviews
, 61
, Article 101097. 10.1016/j.blre.2023.101097.
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J
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Jeyakumar, Jey M;
Kia, Azadeh;
Tam, Lawrence CS;
McIntosh, Jenny;
Spiewak, Justyna;
Mills, Kevin;
Heywood, Wendy;
... Nathwani, Amit; + view all
(2023)
Preclinical evaluation of FLT190, a liver-directed AAV gene therapy for Fabry disease.
Gene Therapy
10.1038/s41434-022-00381-y.
(In press).
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Jha, R;
Kinna, A;
Hotblack, A;
Bughda, R;
Bulek, A;
Gannon, I;
Ilca, T;
... Pule, M; + view all
(2023)
Designer Small-Molecule Control System Based on Minocycline-Induced Disruption of Protein–Protein Interaction.
ACS Chemical Biology
, 19
(2)
pp. 308-324.
10.1021/acschembio.3c00521.
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K
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Katipally, Rohan R;
Martinez, Carlos A;
Pugh, Siân A;
Bridgewater, John A;
Primrose, John N;
Domingo, Enric;
Maughan, Timothy S;
... with the S:CORT Consortium; + view all
(2023)
Integrated Clinical-Molecular Classification of Colorectal Liver Metastases: A Biomarker Analysis of the Phase 3 New EPOC Randomized Clinical Trial.
JAMA Oncology
10.1001/jamaoncol.2023.2535.
(In press).
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Kefas, Joanna;
Bridgewater, John;
Vogel, Arndt;
Stein, Alexander;
Primrose, John;
(2023)
Adjuvant therapy of biliary tract cancers.
Therapeutic Advances in Medical Oncology
, 15
10.1177/17588359231163785.
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Khan, Abdullah O;
Rodriguez-Romera, Antonio;
Reyat, Jasmeet S;
Olijnik, Aude-Anais;
Colombo, Michela;
Wang, Guanlin;
Wen, Wei Xiong;
... Psaila, Bethan; + view all
(2023)
Human bone marrow organoids for disease modelling, discovery and validation of therapeutic targets in hematological malignancies.
Cancer Discovery
, 13
(2)
pp. 364-385.
10.1158/2159-8290.CD-22-0199.
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Kirkeby, Agnete;
Nelander, Jenny;
Hoban, Deirdre B;
Rogelius, Nina;
Bjartmarz, Hjálmar;
Novo Nordisk Cell Therapy R&D;
Storm, Petter;
... Parmar, Malin; + view all
(2023)
Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson’s disease, STEM-PD.
Cell Stem Cell
, 30
(10)
1299-1314.E9.
10.1016/j.stem.2023.08.014.
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Kokalaki, E;
Ma, B;
Ferrari, M;
Grothier, T;
Hazelton, W;
Manzoor, S;
Costu, E;
... Pule, M; + view all
(2023)
Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR.
Molecular Therapy
, 31
(7)
pp. 2089-2104.
10.1016/j.ymthe.2023.03.020.
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Kuhnl, A;
Kirkwood, AA;
Roddie, C;
Menne, T;
Tholouli, E;
Bloor, A;
Besley, C;
... Townsend, W; + view all
(2023)
CAR T in patients with large B-cell lymphoma not fit for autologous transplant.
British Journal of Haematology
, 202
(1)
pp. 65-73.
10.1111/bjh.18810.
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L
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Lee, Lydia;
Lim, Wen Chean;
Galas-Filipowicz, Daria;
Fung, Kent;
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