Browse by UCL people
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Number of items: 96.
Article
Adams, D;
Baldock, R;
Bhattacharya, S;
Copp, AJ;
Dickinson, M;
Greene, NDE;
Henkelman, M;
... West, D; + view all
(2013)
Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening.
Disease Models and Mechanisms
, 6
(3)
pp. 571-579.
10.1242/dmm.011833.
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Ampartzidis, Ioakeim;
Efstathiou, Christoforos;
Paonessa, Francesco;
Thompson, Elliott M;
Wilson, Tyler;
McCann, Conor J;
Greene, Nicholas DE;
... Galea, Gabriel L; + view all
(2023)
Synchronisation of apical constriction and cell cycle progression is a conserved behaviour of pseudostratified neuroepithelia informed by their tissue geometry.
Developmental Biology
, 494
pp. 60-70.
10.1016/j.ydbio.2022.12.002.
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Autuori, MC;
Pai, YJ;
Stuckey, DJ;
Savery, D;
Marconi, AM;
Massa, V;
Lythgoe, MF;
... Greene, NDE; + view all
(2017)
Use of high-frequency ultrasound to study the prenatal development of cranial neural tube defects and hydrocephalus in Gldc-deficient mice.
Prenatal Diagnosis
, 37
(3)
pp. 273-281.
10.1002/pd.5004.
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Bahous, RH;
Jadavji, NM;
Deng, L;
Cosin-Tomas, M;
Lu, J;
Malysheva, O;
Leung, K-Y;
... Rozen, R; + view all
(2017)
High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring.
HUMAN MOLECULAR GENETICS
, 26
(5)
pp. 888-900.
10.1093/hmg/ddx004.
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Baumholtz, AI;
Simard, A;
Nikolopoulou, E;
Oosenbrug, M;
Collins, MM;
Piontek, A;
Krause, G;
... Ryan, AK; + view all
(2017)
Claudins are essential for cell shape changes and convergent extension movements during neural tube closure.
Developmental Biology
, 428
(1)
pp. 25-38.
10.1016/j.ydbio.2017.05.013.
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Bookey, Niamh;
Drago, Paola;
Leung, Kit-Yi;
Hughes, Linda;
MacCooey, Aoife;
Ozaki, Mari;
Henry, Michael;
... Parle-McDermott, Anne; + view all
(2024)
The Differential Translation Capabilities of the Human DHFR2 Gene Indicates a Developmental and Tissue-Specific Endogenous Protein of Low Abundance.
Mol Cell Proteomics
, 23
(3)
, Article 100718. 10.1016/j.mcpro.2024.100718.
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Butler, MB;
Short, NE;
Maniou, E;
Alexandre, P;
Greene, NDE;
Copp, AJ;
Galea, GL;
(2019)
Rho kinase-dependent apical constriction counteracts M-phase apical expansion to enable mouse neural tube closure.
Journal of Cell Science
, 132
, Article jcs230300. 10.1242/jcs.230300.
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Carnaghan, H;
Roberts, T;
Savery, D;
Norris, FC;
McCann, CJ;
Copp, AJ;
Scambler, PJ;
... Eaton, S; + view all
(2013)
Novel exomphalos genetic mouse model: The importance of accurate phenotypic classification.
J Pediatr Surg
, 48
(10)
2036 - 2042.
10.1016/j.jpedsurg.2013.04.010.
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Cearns, MD;
Escuin, S;
Alexandre, P;
Greene, ND;
Copp, AJ;
(2016)
Microtubules, polarity and vertebrate neural tube morphogenesis.
Journal of Anatomy
, 229
(1)
pp. 63-74.
10.1111/joa.12468.
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Che, Xiaoyu;
Liu, Jufen;
Galea, Gabriel L;
Zhang, Yali;
Greene, Nicholas DE;
Zhang, Le;
Jin, Lei;
... Li, Zhiwen; + view all
(2022)
Non-Isolated Neural Tube Defects with Comorbid Malformations Are Responsive to Population-Level Folic Acid Supplementation in Northern China.
Biology
, 11
(9)
, Article 1371. 10.3390/biology11091371.
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Christensen, KE;
Mikael, LG;
Leung, KY;
Lévesque, N;
Deng, L;
Wu, Q;
Malysheva, OV;
... Rozen, R; + view all
(2015)
High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice.
The American Journal of Clinical Nutrition
, 101
(3)
646 - 658.
10.3945/ajcn.114.086603.
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Copp, AJ;
Greene, NDE;
Jao, J;
Zash, R;
Mohan, H;
Dontsova, V;
Serghides, L;
(2022)
Dolutegravir and rat whole embryo culture.
Birth Defects Research
, 114
(1)
pp. 23-24.
10.1002/bdr2.1969.
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Copp, Andrew J;
Clark, Maryam;
Greene, Nicholas DE;
(2023)
Morphological phenotyping after mouse whole embryo culture.
Frontiers in Cell and Developmental Biology
, 11
pp. 1-13.
10.3389/fcell.2023.1223849.
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Copp, AJ;
Adzick, NS;
Chitty, LS;
Fletcher, JM;
Holmbeck, GN;
Shaw, GM;
(2015)
Spina bifida.
Nature Reviews Disease Primers
, 1
, Article 15007. 10.1038/nrdp.2015.7.
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Copp, AJ;
Greene, NDE;
(2013)
Neural tube defects-disorders of neurulation and related embryonic processes.
Wiley Interdisciplinary Reviews: Developmental Biology
, 2
(2)
pp. 213-227.
10.1002/wdev.71.
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Copp, AJ;
Stanier, P;
Greene, NDE;
(2013)
Neural tube defects: recent advances, unsolved questions, and controversies.
The Lancet Neurology
, 12
(8)
pp. 799-810.
10.1016/S1474-4422(13)70110-8.
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Crane-Smith, Zoe;
De Castro, Sandra CP;
Nikolopoulou, Evanthia;
Wolujewicz, Paul;
Smedley, Damian;
Lei, Yunping;
Mather, Emma;
... Greene, Nicholas DE; + view all
(2023)
A non-coding insertional mutation of Grhl2 causes gene over-expression and multiple structural anomalies including cleft palate, spina bifida and encephalocele.
Human Molecular Genetics
10.1093/hmg/ddad094.
(In press).
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Culshaw, LH;
Savery, D;
Greene, NDE;
Copp, AJ;
(2019)
Mouse whole embryo culture: Evaluating the requirement for rat serum as culture medium.
Birth Defects Research
, 111
(16)
pp. 1165-1177.
10.1002/bdr2.1538.
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D'Souza, SW;
Copp, AJ;
Greene, NDE;
Glazier, JD;
(2020)
Maternal Inositol Status and Neural Tube Defects: A Role for the Human Yolk Sac in Embryonic Inositol Delivery?
Advances in Nutrition
10.1093/advances/nmaa100.
(In press).
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De Castro, SC;
Malhas, A;
Leung, KY;
Gustavsson, P;
Vaux, DJ;
Copp, AJ;
Greene, ND;
(2012)
Lamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in mice.
PLoS Genet
, 8
(11)
, Article e1003059. 10.1371/journal.pgen.1003059.
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De Castro, SCP;
Gustavsson, P;
Marshall, AR;
Gordon, WM;
Galea, G;
Nikolopoulou, E;
Savery, D;
... Greene, NDE; + view all
(2018)
Over-expression of Grainyhead-like 3 causes spina bifida and interacts genetically with mutant alleles of Grhl2 and Vangl2 in mice.
Human Molecular Genetics
, 27
(24)
pp. 4218-4230.
10.1093/hmg/ddy313.
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De Castro, SCP;
Hirst, CS;
Savery, D;
Rolo, A;
Lickert, H;
Andersen, B;
Copp, AJ;
(2019)
Neural tube closure depends on expression of Grainyhead-like 3 in multiple tissues.
Developmental Biology
, 435
(2)
pp. 130-137.
10.1016/j.ydbio.2018.01.016.
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Dinicola, S;
Unfer, V;
Facchinetti, F;
Soulage, CO;
Greene, ND;
Bizzarri, M;
Laganà, AS;
... Wdowiak, A; + view all
(2021)
Inositols: From Established Knowledge to Novel Approaches.
International Journal of Molecular Sciences
, 22
(19)
, Article 10575. 10.3390/ijms221910575.
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Dontsova, Valeriya;
Mohan, Haneesha;
Blanco, Camille;
Jao, Jennifer;
Greene, Nicholas DE;
Copp, Andrew J;
Zash, Rebecca;
(2023)
Metabolic implications and safety of dolutegravir use in pregnancy.
The Lancet HIV
, 10
(9)
e606-e616.
10.1016/S2352-3018(23)00141-8.
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Escuin, S;
Vernay, B;
Savery, D;
Gurniak, CB;
Witke, W;
Greene, NDE;
Copp, AJ;
(2015)
Rho-kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closure.
JOURNAL OF CELL SCIENCE
, 128
(14)
pp. 2468-2481.
10.1242/jcs.164574.
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Escuin, Sarah;
Raza-Knight, Saba Rose;
Savery, Dawn;
Gaston-Massuet, Carles;
Galea, Gabriel L;
Greene, Nicholas DE;
Copp, Andrew J;
(2023)
Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse.
Disease Models and Mechanisms
, 16
(3)
, Article dmm049858. 10.1242/dmm.049858.
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Essmann, CL;
Martinez-Martinez, D;
Pryor, R;
Leung, K-Y;
Krishnan, KB;
Lui, PP;
Greene, NDE;
... Cabreiro, F; + view all
(2020)
Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans.
Nature Communications
, 11
(1)
, Article 1043. 10.1038/s41467-020-14785-0.
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Facchinetti, F;
Cavalli, P;
Copp, AJ;
D'Anna, R;
Kandaraki, E;
Greene, NDE;
Unfer, V;
(2020)
An update on the use of inositols in preventing gestational diabetes mellitus (GDM) and neural tube defects (NTDs).
Expert Opinion on Drug Metabolism & Toxicology
, 16
(12)
pp. 1189-1198.
10.1080/17425255.2020.1828344.
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Fons, JM;
Mozaffari, M;
Malik, D;
Marshall, AR;
Connor, S;
Greene, NDE;
Tucker, AS;
(2020)
Epithelial dynamics shed light on mechanisms underlying ear canal defects.
Development
, 147
(23)
, Article dev194654. 10.1242/dev.194654.
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Galea, GL;
Cho, Y-J;
Galea, G;
Mole, MA;
Rolo, A;
Savery, D;
Moulding, D;
... Copp, AJ; + view all
(2017)
Biomechanical coupling facilitates spinal neural tube closure in mouse embryos.
PNAS - Proceedings of the National Academy of Sciences of the United States of America
, 114
(26)
E5177-E5186.
10.1073/pnas.1700934114.
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Galea, GL;
Maniou, E;
Edwards, TJ;
Marshall, AR;
Ampartzidis, I;
Greene, NDE;
Copp, AJ;
(2021)
Cell non-autonomy amplifies disruption of neurulation by mosaic Vangl2 deletion in mice.
Nature Communications
, 12
(1)
, Article 1159. 10.1038/s41467-021-21372-4.
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Galea, GL;
Nychyk, O;
Mole, MA;
Moulding, D;
Savery, D;
Nikolopoulou, E;
Henderson, DJ;
... Copp, AJ; + view all
(2018)
Vangl2 disruption alters the biomechanics of late spinal neurulation leading to spina bifida in mouse embryos.
Disease Models & Mechanisms
, 11
(3)
, Article dmm032219. 10.1242/dmm.032219.
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Greene, N. D.E.;
Stanier, P.;
Copp, A. J.;
(2009)
Genetics of human neural tube defects.
Human Molecular Genetics
, 18
(R2)
R113-R129.
10.1093/hmg/ddp347.
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Greene, ND;
Copp, AJ;
(2014)
Neural tube defects.
Annual Review of Neuroscience
, 37
pp. 221-242.
10.1146/annurev-neuro-062012-170354.
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Greene, ND;
Leung, KY;
Copp, AJ;
(2017)
Inositol, neural tube closure and the prevention of neural tube defects.
Birth Defects Research
, 109
(2)
pp. 68-80.
10.1002/bdra.23533.
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Greene, ND;
Leung, KY;
Gay, V;
Burren, K;
Mills, K;
Chitty, LS;
Copp, AJ;
(2016)
Inositol for the prevention of neural tube defects: a pilot randomised controlled trial.
British Journal of Nutrition
, 115
(6)
pp. 974-983.
10.1017/S0007114515005322.
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Harlan De Crescenzo, A;
Panoutsopoulos, AA;
Tat, L;
Schaaf, Z;
Racherla, S;
Henderson, L;
Leung, K-Y;
... Zarbalis, KS; + view all
(2020)
Deficient or Excess Folic Acid Supply During Pregnancy Alter Cortical Neurodevelopment in Mouse Offspring.
Cerebral Cortex
, Article bhaa248. 10.1093/cercor/bhaa248.
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Henderson, DJ;
Conway, SJ;
Greene, NDE;
Gerrelli, D;
Murdoch, JN;
Anderson, RH;
Copp, AJ;
(2001)
Cardiovascular defects associated with abnormalities in midline development in the Loop-tail mouse mutant.
CIRCULATION RESEARCH
, 89
(1)
pp. 6-12.
10.1161/hh1301.092497.
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Hughes, A;
Greene, NDE;
Copp, AJ;
Galea, GL;
(2017)
Valproic acid disrupts the biomechanics of late spinal neural tube closure in mouse embryos.
Mechanisms of Development
, 149
pp. 20-26.
10.1016/j.mod.2017.12.001.
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Ishida, M;
Cullup, T;
Boustred, C;
James, C;
Docker, J;
English, C;
GOSgene, .;
... Stanier, PM; + view all
(2018)
A targeted sequencing panel identifies rare damaging variants in multiple genes in the cranial neural tube defect, anencephaly.
Clinical Genetics
, 93
(4)
pp. 870-879.
10.1111/cge.13189.
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Jamet, Sophie;
Ha, Seungshin;
Ho, Tzu-Hua;
Houghtaling, Scott;
Timms, Andrew;
Yu, Kai;
Paquette, Alison;
... Beier, David R; + view all
(2022)
The Arginine Methyltransferase Carm1 is Necessary for Heart Development.
G3: Genes | Genomes | Genetics
, Article jkac155. 10.1093/g3journal/jkac155.
(In press).
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Lang, MB;
Leung, KY;
Greene, NDE;
Malone, KM;
Saginc, G;
Randi, AM;
Kiprianos, A;
... Mason, JC; + view all
(2023)
The actions of methotrexate on endothelial cells are dependent on the shear stress-induced regulation of one carbon metabolism.
Frontiers in Immunology
, 14
, Article 1209490. 10.3389/fimmu.2023.1209490.
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Leung, Kit-Yi;
Weston, Eleanor;
De Castro, Sandra CP;
Nikolopoulou, Evanthia;
Sudiwala, Sonia;
Savery, Dawn;
Eaton, Simon;
... Greene, Nicholas DE; + view all
(2024)
Association of embryonic inositol status with susceptibility to neural tube defects, metabolite profile, and maternal inositol intake.
FASEB Journal
, 38
(11)
, Article e23738. 10.1096/fj.202400206R.
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Leung, K-Y;
De Castro, SCP;
Galea, GL;
Copp, AJ;
Greene, NDE;
(2021)
Glycine Cleavage System H Protein Is Essential for Embryonic Viability, Implying Additional Function Beyond the Glycine Cleavage System.
Frontiers in Genetics
, 12
, Article 625120. 10.3389/fgene.2021.625120.
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Leung, K-Y;
De Castro, SCP;
Santos, C;
Savery, D;
Prunty, H;
Gold-Diaz, D;
Bennett, S;
... Greene, NDE; + view all
(2020)
Regulation of glycine metabolism by the glycine cleavage system and conjugation pathway in mouse models of Non-Ketotic Hyperglycinemia.
Journal of Inherited Metabolic Disease
, 43
(6)
pp. 1186-1198.
10.1002/jimd.12295.
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Leung, K-Y;
Pai, YJ;
Chen, Q;
Santos, C;
Calvani, E;
Sudiwala, S;
Savery, D;
... Greene, NDE; + view all
(2017)
Partitioning of One-Carbon Units in Folate and Methionine Metabolism Is Essential for Neural Tube Closure.
Cell Rep
, 21
(7)
pp. 1795-1808.
10.1016/j.celrep.2017.10.072.
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Leung, KY;
De Castro, SC;
Savery, D;
Copp, AJ;
Greene, ND;
(2013)
Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse.
Brain: A Journal of Neurology
, 136
(9)
pp. 2836-2841.
10.1093/brain/awt209.
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Lin, S;
Ren, A;
Wang, L;
Santos, C;
Huang, Y;
Jin, L;
Li, Z;
(2019)
Aberrant methylation of Pax3 gene and neural tube defects in association with exposure to polycyclic aromatic hydrocarbons.
Clinical Epigenetics
, 11
(1)
, Article 13. 10.1186/s13148-019-0611-7.
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Lin, S;
Wang, L;
Huang, Y;
Wang, Y;
Wang, C;
Greene, NDE;
Ren, A;
(2018)
Oxidative Stress and Apoptosis in Benzo[a]pyrene-Induced Neural Tube Defects.
Free Radical Biology and Medicine
, 116
pp. 149-158.
10.1016/j.freeradbiomed.2018.01.004.
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Liu, J;
Zhang, Y;
Zhang, L;
Jin, L;
Greene, N;
Li, Z;
Ren, A;
(2021)
Preplanned Studies: Orofacial Clefts in High Prevalence Area of Birth Defects — Five Counties, Shanxi Province, China, 2000–2020.
China CDC Weekly
, 3
(37)
pp. 773-777.
10.46234/ccdcw2021.192.
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Liu, J;
Li, Z;
Greene, NDE;
Li, H;
Ren, A;
(2017)
The recurrence risk of neural tube defects (NTDs) in a population with high prevalence of NTDs in northern China.
Oncotarget
, 8
(42)
pp. 72577-72583.
10.18632/oncotarget.19890.
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Liu, J;
Xie, J;
Li, Z;
Greene, NDE;
Ren, A;
(2018)
Sex differences in the prevalence of neural tube defects and preventive effects of folic acid (FA) supplementation among five counties in northern China: results from a population-based birth defect surveillance programme.
BMJ Open
, 8
(11)
, Article e022565. 10.1136/bmjopen-2018-022565.
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Maniou, E;
Staddon, MF;
Marshall, AR;
Greene, NDE;
Copp, AJ;
Banerjee, S;
Galea, GL;
(2021)
Hindbrain neuropore tissue geometry determines asymmetric cell-mediated closure dynamics in mouse embryos.
Proceedings of the National Academy of Sciences
, 118
(19)
, Article e2023163118. 10.1073/pnas.2023163118.
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Marshall, Abigail R;
Galea, Gabriel L;
Copp, Andrew J;
Greene, Nicholas DE;
(2023)
The surface ectoderm exhibits spatially heterogenous tension that correlates with YAP localisation during spinal neural tube closure in mouse embryos.
Cells & Development
, 174
, Article 203840. 10.1016/j.cdev.2023.203840.
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Marshall, Abigail R;
Maniou, Eirini;
Moulding, Dale;
Greene, Nicholas DE;
Copp, Andrew J;
Galea, Gabriel L;
(2022)
Two-Photon Cell and Tissue Level Laser Ablation Methods to Study Morphogenetic Biomechanics.
Methods in Molecular Biology
, 2438
pp. 217-230.
10.1007/978-1-0716-2035-9_14.
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Massa, V;
Avagliano, L;
Grazioli, P;
De Castro, SCP;
Parodi, C;
Savery, D;
Vergani, P;
... Greene, NDE; + view all
(2019)
Dynamic acetylation profile during mammalian neurulation.
Birth Defects Research
10.1002/bdr2.1618.
(In press).
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Massa, V.;
Greene, N.D.E.;
Copp, A.J.;
(2009)
Do cells become homeless during neural tube closure?
Cell Cycle
, 8
(16)
pp. 2479-2480.
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McShane, SG;
Molè, MA;
Savery, D;
Greene, ND;
Tam, PP;
Copp, AJ;
(2015)
Cellular basis of neuroepithelial bending during mouse spinal neural tube closure.
Developmental Biology
, 404
(2)
pp. 113-124.
10.1016/j.ydbio.2015.06.003.
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Medeiros, Tânia Catarina;
Ovciarikova, Jana;
Li, Xianhe;
Krueger, Patrick;
Bartsch, Tim;
Reato, Silvia;
Crow, John C;
... Pernas, Lena; + view all
(2025)
Mitochondria protect against an intracellular pathogen by restricting access to folate.
Science
, 389
(6761)
, Article eadr6326. 10.1126/science.adr6326.
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Mohan, Haneesha;
Nguyen, Jessica;
Yee, Audrey;
Laurette, Evelyn Yukino;
Sanghvi, Tanvi;
Tejada, Oscar;
Jao, Jennifer;
... Serghides, Lena; + view all
(2025)
Fetal Defects in Mice Treated with Integrase Strand Transfer Inhibitors: Comparison of Dolutegravir, Raltegravir, Bictegravir and Cabotegravir.
The Journal of Infectious Diseases
, Article jiaf362. 10.1093/infdis/jiaf362.
(In press).
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Mohan, H;
Guzman Lenis, M;
Laurette, EY;
Tejada, O;
Sanghvi, T;
Leung, K-Y;
Cahill, LS;
... Serghides, L; + view all
(2021)
In response to the Letter to the Editor by Romach et al. re our publication "Dolutegravir in pregnant mice is associated with increased rates of fetal defects at therapeutic but not at supratherapeutic levels".
EBioMedicine
, 66
, Article 103334. 10.1016/j.ebiom.2021.103334.
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Mohan, H;
Lenis, MG;
Laurette, EY;
Tejada, O;
Sanghvi, T;
Leung, K-Y;
Cahill, LS;
... Serghides, L; + view all
(2021)
Dolutegravir in pregnant mice is associated with increased rates of fetal defects at therapeutic but not at supratherapeutic levels.
EBioMedicine
, 63
, Article 103167. 10.1016/j.ebiom.2020.103167.
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Mohd-Zin, Siti Waheeda;
Tan, Amelia Cheng Wei;
Atroosh, Wahib M;
Thong, Meow-Keong;
Azizi, Abu Bakar;
Greene, Nicholas DE;
Abdul-Aziz, Noraishah Mydin;
(2022)
Eph and Ephrin Variants in Malaysian Neural Tube Defect Families.
Genes
, 13
(6)
, Article 952. 10.3390/genes13060952.
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Mohd-Zin, SW;
Abdullah, N-L;
Abdullah, A;
Greene, NDE;
Cheah, P-S;
Ling, K-H;
Yusof, H;
... Abdul-Aziz, NM; + view all
(2016)
Identification of the genomic mutation in Epha4rb-2J/rb-2J mice.
Genome
, 59
(7)
pp. 439-448.
10.1139/gen-2015-0142.
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Molè, MA;
Galea, GL;
Rolo, A;
Weberling, A;
Nychyk, O;
De Castro, SC;
Savery, D;
... Copp, AJ; + view all
(2020)
Integrin-Mediated Focal Anchorage Drives Epithelial Zippering during Mouse Neural Tube Closure.
Developmental Cell
, 52
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321-334.e6.
10.1016/j.devcel.2020.01.012.
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Murdoch, JN;
Damrau, C;
Paudyal, A;
Bogani, D;
Wells, S;
Greene, ND;
Stanier, P;
(2014)
Genetic interactions between planar cell polarity genes cause diverse neural tube defects in mice.
Dis Model Mech
, 7
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1153 - 1163.
10.1242/dmm.016758.
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Nikolopoulou, E;
Galea, GL;
Rolo, A;
Greene, ND;
Copp, AJ;
(2017)
Neural tube closure: cellular, molecular and biomechanical mechanisms.
Development
, 144
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pp. 552-566.
10.1242/dev.145904.
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Nikolopoulou, E;
Hirst, CS;
Galea, G;
Venturini, C;
Moulding, D;
Marshall, AR;
Rolo, A;
... Greene, NDE; + view all
(2019)
Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2.
Nature Communications
, 10
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Nivrenjeet, S;
Mohd-Zin, SW;
Nisheljeet, S;
Azizi, AB;
Palaniandy, K;
Firdaus-Raih, M;
Ariffin, MHM;
... Abdul-Aziz, NM; + view all
(2022)
Inflammation in embryology: A review of neuroinflammation in spina bifida.
Neuroscience Research Notes
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, Article 132. 10.31117/neuroscirn.v5i1.132.
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Norris, FC;
Siow, BM;
Cleary, JO;
Wells, JA;
De Castro, SC;
Ordidge, RJ;
Greene, ND;
... Lythgoe, MF; + view all
(2015)
Diffusion microscopic MRI of the mouse embryo: Protocol and practical implementation in the splotch mouse model.
Magnetic Resonance in Medicine
, 73
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731 - 739.
10.1002/mrm.25145.
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Nychyk, O;
Galea, GL;
Molè, M;
Savery, D;
Greene, NDE;
Stanier, P;
Copp, AJ;
(2021)
Vangl2-environment interaction causes severe neural tube defects, without abnormal neuroepithelial convergent extension.
Disease Models & Mechanisms
10.1242/dmm.049194.
(In press).
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Orriss, IR;
Lanham, S;
Savery, D;
Greene, NDE;
Stanier, P;
Oreffo, R;
Copp, AJ;
(2018)
Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice.
Scientific Reports
, 8
, Article 3325. 10.1038/s41598-018-21718-x.
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Pai, Y-J;
Abdullah, NL;
Mohd-Zin, SW;
Mohammed, RS;
Rolo, A;
Greene, NDE;
Abdul-Aziz, NM;
(2012)
Epithelial fusion during neural tube morphogenesis.
Birth Defects Research Part A: Clinical and Molecular Teratology
, 94
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pp. 817-823.
10.1002/bdra.23072.
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Pai, YJ;
Leung, KY;
Savery, D;
Hutchin, T;
Prunty, H;
Heales, S;
Brosnan, ME;
... Greene, ND; + view all
(2015)
Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice.
Nat Commun
, 6
, Article 6388. 10.1038/ncomms7388.
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Palmer, AJ;
Savery, D;
Massa, V;
Copp, AJ;
Greene, NDE;
(2021)
Genetic interaction of Pax3 mutation and canonical Wnt signaling modulates neural tube defects and neural crest abnormalities.
Genesis
, Article e23445. 10.1002/dvg.23445.
(In press).
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Perry, CJ;
Finch, P;
Müller-Taubenberger, A;
Leung, K-Y;
Warren, EC;
Damstra-Oddy, J;
Sharma, D;
... Williams, RSB; + view all
(2020)
A new mechanism for Cannabidiol in regulating the one-carbon cycle and methionine levels in Dictyostelium and in mammalian epilepsy models.
British Journal of Pharmacology
, 177
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pp. 912-928.
10.1111/bph.14892.
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Pravenec, M;
Leung, K-Y;
Zidek, V;
Mlejnek, P;
Simakova, M;
Silhavy, J;
Kozich, V;
(2018)
Genetically Determined Folate Deficiency Is Associated With Abnormal Hepatic Folate Profiles in the Spontaneously Hypertensive Rat.
Physiological Research
, 67
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pp. 417-422.
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Pryor, SE;
Massa, V;
Savery, D;
Andre, P;
Yang, Y;
Greene, ND;
Copp, AJ;
(2014)
Vangl-dependent planar cell polarity signalling is not required for neural crest migration in mammals.
Development
, 141
pp. 3153-3158.
10.1242/dev.111427.
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Pryor, SE;
Massa, V;
Savery, D;
Greene, NDE;
Copp, AJ;
(2012)
Convergent extension analysis in mouse whole embryo culture.
Methods in Molecular Biology
, 839
pp. 133-146.
10.1007/978-1-61779-510-7_11.
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Riche, R;
Liao, M;
Pena, IA;
Leung, KY;
Lepage, N;
Greene, NDE;
Sarafoglou, K;
... Samarut, E; + view all
(2018)
Glycine decarboxylase deficiency-induced motor dysfunction in zebrafish is rescued by counterbalancing glycine synaptic level.
JCI Insight
, 3
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, Article e124642. 10.1172/jci.insight.124642.
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Robinson, A;
Partridge, D;
Malhas, A;
De Castro, SC;
Gustavsson, P;
Thompson, DN;
Vaux, DJ;
... Greene, ND; + view all
(2013)
Is LMNB1 a susceptibility gene for neural tube defects in humans?
Birth Defects Research Part A: Clinical and Molecular Teratology
, 97
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pp. 398-402.
10.1002/bdra.23141.
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Rolo, A;
Escuin, S;
Greene, ND;
Copp, AJ;
(2018)
Rho GTPases in mammalian spinal neural tube closure.
Small GTPases
, 9
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pp. 283-289.
10.1080/21541248.2016.1235388.
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Rolo, A;
Galea, GL;
Savery, D;
Greene, NDE;
Copp, AJ;
(2019)
Novel mouse model of encephalocele: post-neurulation origin and relationship to open neural tube defects.
Disease Models & Mechanisms
10.1242/dmm.040683.
(In press).
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Rolo, A;
Savery, D;
Escuin, S;
de Castro, SC;
Armer, HE;
Munro, PM;
Molè, MA;
... Copp, AJ; + view all
Regulation of cell protrusions by small GTPases during fusion of the neural folds.
Elife
, 5
, Article e13273. 10.7554/eLife.13273.
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Santos, C;
Pai, YJ;
Mahmood, MR;
Leung, K-Y;
Savery, D;
Waddington, SN;
Copp, AJ;
(2020)
Impaired folate one-carbon metabolism causes formate-preventable hydrocephalus in glycine decarboxylase-deficient mice.
Journal of Clinical Investigation
, 130
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pp. 1446-1452.
10.1172/jci132360.
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Savery, D;
Maniou, E;
Culshaw, LH;
Greene, NDE;
Copp, AJ;
Galea, GL;
(2019)
Refinement of inducible gene deletion in embryos of pregnant mice.
Birth Defects Research
10.1002/bdr2.1628.
(In press).
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Scott, TA;
Quintaneiro, LM;
Norvaisas, P;
Lui, PP;
Wilson, MP;
Leung, K-Y;
Herrera-Dominguez, L;
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(2017)
Host-Microbe Co-metabolism Dictates Cancer Drug Efficacy in C. elegans.
Cell
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442-456.e18.
10.1016/j.cell.2017.03.040.
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Sudiwala, S;
De Castro, SC;
Leung, KY;
Brosnan, JT;
Brosnan, ME;
Mills, K;
Copp, AJ;
(2016)
Formate supplementation enhances folate-dependent nucleotide biosynthesis and prevents spina bifida in a mouse model of folic acid-resistant neural tube defects.
Biochimie
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pp. 63-70.
10.1016/j.biochi.2016.02.010.
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Sudiwala, S;
Palmer, A;
Massa, V;
Burns, AJ;
Dunlevy, LPE;
De Castro, SCP;
Savery, D;
... Greene, NDE; + view all
(2019)
Cellular mechanisms underlying Pax3-related neural tube defects and their prevention by folic acid.
Disease Models & Mechanisms
10.1242/dmm.042234.
(In press).
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Unfer, V;
Kandaraki, E;
Pkhaladze, L;
Roseff, S;
Vazquez-Levin, MH;
Laganà, AS;
Shiao-Yng, C;
... Nestler, J; + view all
(2024)
When one size does not fit all: Reconsidering PCOS etiology, diagnosis, clinical subgroups, and subgroup-specific treatments.
Endocrine and Metabolic Science
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, Article 100159. 10.1016/j.endmts.2024.100159.
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Weston, Eleanor;
Pangilinan, Faith;
Eaton, Simon;
Orford, Michael;
Leung, Kit-Yi;
Copp, Andrew J;
Mills, James L;
... Greene, Nicholas DE; + view all
(2022)
Investigating Genetic Determinants of Plasma Inositol Status in Adult Humans.
The Journal of Nutrition
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pp. 2333-2342.
10.1093/jn/nxac204.
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Ybot-Gonzalez, P;
Greene, NDE;
Copp, AJ;
Henderson, DJ;
Massa, V;
(2023)
Editorial: Maternal-foetal crosstalk impacts on offspring development.
Frontiers in Cell and Developmental Biology
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, Article 1133159. 10.3389/fcell.2023.1133159.
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Zhang, Y;
Liu, J;
Zhang, L;
Jin, L;
D E Greene, N;
Li, Z;
Ren, A;
(2021)
Passive Smoking During the Periconceptional Period and Risk for Neural Tube Defects in Offspring — Five Counties, Shanxi Province, China, 2010–2016.
China CDC Weekly
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pp. 778-782.
10.46234/ccdcw2021.193.
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Book chapter
|
Copp, A;
Jones, V;
Greene, N;
(2019)
Genetics and Developmental Biology of Closed Dysraphic Conditions.
In: Tubbs, RS and Oskouian, RJ and Blount, JP and Oakes, WJ, (eds.)
Occult Spinal Dysraphism.
(pp. 325-344).
Springer: Cham, Switzerland.
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Working / discussion paper
|
Ampartzidis, Ioakeim;
Efstathiou, Christoforos;
Paonessa, Francesco;
Thompson, Elliott;
Wilson, Tyler;
McCann, Conor;
Greene, Nicholas DE;
... Galea, Gabriel; + view all
(2022)
Synchronisation of apical constriction and cell cycle progression is a conserved behaviour of pseudostratified neuroepithelia informed by their tissue geometry.
BioRxiv: Cold Spring Harbor, NY, USA.
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Thesis
|
Danielsen, KE;
(2016)
Cell cycle heterogeneity as a regulator of epithelial bending during neural tube closure.
Doctoral thesis , UCL (University College London).
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