UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Novel exomphalos genetic mouse model: The importance of accurate phenotypic classification.

Carnaghan, H; Roberts, T; Savery, D; Norris, FC; McCann, CJ; Copp, AJ; Scambler, PJ; ... Eaton, S; + view all (2013) Novel exomphalos genetic mouse model: The importance of accurate phenotypic classification. J Pediatr Surg , 48 (10) 2036 - 2042. 10.1016/j.jpedsurg.2013.04.010. Green open access

[thumbnail of 1-s2.0-S0022346813003527-main.pdf]
Preview
 PDF
1-s2.0-S0022346813003527-main.pdf
Download (1MB)

Abstract

Rodent models of abdominal wall defects (AWD) may provide insight into the pathophysiology of these conditions including gut dysfunction in gastroschisis, or pulmonary hypoplasia in exomphalos. Previously, a Scribble mutant mouse model (circletail) was reported to exhibit gastroschisis. We further characterise this AWD in Scribble knockout mice.

Type: Article
Title: Novel exomphalos genetic mouse model: The importance of accurate phenotypic classification.
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.jpedsurg.2013.04.010
Publisher version: http://dx.doi.org/10.1016/j.jpedsurg.2013.04.010
Language: English
Additional information: © 2013 Elsevier Inc. Open access under CC BY license.
Keywords: Abdominal wall defect, Exomphalos, Gastroschisis, In amnio micro-MRI, Interstitial cells of Cajal, Rodent model, Scrib
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Experimental and Translational Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept
URI: https://discovery.ucl.ac.uk/id/eprint/1393441
Downloads since deposit
138Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item