Browse by UCL people
Group by: Type | Date
Number of items: 118.
Article
Abdalla, Y;
Ferianc, M;
Awad, A;
Kim, J;
Elbadawi, M;
Basit, AW;
Orlu, M;
(2024)
Smart laser Sintering: Deep Learning-Powered powder bed fusion 3D printing in precision medicine.
International Journal of Pharmaceutics
, 661
, Article 124440. 10.1016/j.ijpharm.2024.124440.
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Abdalla, Youssef;
Ferianc, Martin;
Alfassam, Haya;
Awad, Atheer;
Qiao, Ruochen;
Rodrigues, Miguel;
Orlu, Mine;
... Shorthouse, David; + view all
(2025)
A Novel Semi‐Automated Pipeline for Optimizing 3D‐Printed Drug Formulations.
Advanced Intelligent Systems
10.1002/aisy.202401112.
(In press).
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Abdalla, Youssef;
McCoubrey, Laura E;
Ferraro, Fabiana;
Sonnleitner, Lisa Maria;
Guinet, Yannick;
Siepmann, Florence;
Hedoux, Alain;
... Shorthouse, David; + view all
(2024)
Machine learning of Raman spectra predicts drug release from polysaccharide coatings for targeted colonic delivery.
Journal of Controlled Release
, 374
pp. 103-111.
10.1016/j.jconrel.2024.08.010.
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Abdelhakim, HE;
Williams, GR;
Craig, DQM;
Orlu, M;
Tuleu, C;
(2020)
Human mouthfeel panel investigating the acceptability of electrospun and solvent cast orodispersible films.
International Journal of Pharmaceutics
, 585
, Article 119532. 10.1016/j.ijpharm.2020.119532.
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Alkahtani, Manal E;
Sun, Siyuan;
Chapman, Christopher AR;
Gaisford, Simon;
Orlu, Mine;
Elbadawi, Moe;
Basit, Abdul W;
(2024)
3D printed electro-responsive system with programmable drug release.
Materials Today Advances
, 23
, Article 100509. 10.1016/j.mtadv.2024.100509.
(In press).
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Alkahtani, ME;
Elbadawi, M;
Chapman, CAR;
Green, RA;
Gaisford, S;
Orlu, M;
Basit, AW;
(2023)
Electroactive Polymers for On-Demand Drug Release.
Advanced Healthcare Materials
, Article 2301759. 10.1002/adhm.202301759.
(In press).
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Alkahtani, ME;
Aodah, AH;
Abu Asab, OA;
Basit, AW;
Orlu, M;
Tawfik, EA;
(2021)
Fabrication and Characterization of Fast-Dissolving Films Containing Escitalopram/Quetiapine for the Treatment of Major Depressive Disorder.
Pharmaceutics
, 13
(6)
, Article 891. 10.3390/pharmaceutics13060891.
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Alsaeed, D;
Davies, N;
Gilmartin, JF-M;
Jamieson, E;
Kharicha, K;
Liljas, AEM;
Raimi-Abraham, BT;
... Orlu Gul, M; + view all
(2016)
Older people's priorities in health and social care research and practice: a public engagement workshop.
Research Involvement and Engagement
, 2
, Article 2. 10.1186/s40900-016-0016-0.
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Alsaeed, D;
Furniss, D;
Blandford, A;
Smith, F;
Orlu, M;
(2018)
Carers’ experiences of home enteral feeding: a survey exploring medicines administration challenges and strategies.
Journal of Clinical Pharmacy and Therapeutics
, 43
pp. 359-365.
10.1111/jcpt.12664.
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Alsaeed, D;
Jamieson, E;
Gul, MO;
Smith, FJ;
(2016)
Challenges to optimal medicines use in people living with dementia and their caregivers: A literature review.
International Journal of Pharmaceutics
, 512
(2)
pp. 396-404.
10.1016/j.ijpharm.2015.12.050.
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Alsaeed, D;
Orlu, M;
Smith, F;
(2021)
Optimising medication use along dementia progression: Recommendations from a qualitative study.
Healthcare
, 9
(8)
, Article 982. 10.3390/healthcare9080982.
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Awad, A;
Madla, CM;
McCoubrey, LE;
Ferraro, F;
Gavins, FKH;
Buanz, A;
Gaisford, S;
... Basit, AW; + view all
(2022)
Clinical translation of advanced colonic drug delivery technologies.
Advanced Drug Delivery Reviews
, 181
, Article 114076. 10.1016/j.addr.2021.114076.
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Bakhshi, PK;
Bain, J;
Gul, MO;
Stride, E;
Edirisinghe, M;
Staniland, SS;
(2016)
Manufacturing Man-Made Magnetosomes: High-Throughput In Situ Synthesis of Biomimetic Magnetite Loaded Nanovesicles.
Macromolecular Bioscience
, 16
(11)
pp. 1555-1561.
10.1002/mabi.201600181.
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Bhanu, C;
Nimmons, D;
Petersen, I;
Orlu, M;
Davis, D;
Hussain, H;
Magammanage, S;
(2021)
Drug-induced orthostatic hypotension: A systematic review and meta-analysis of randomised controlled trials.
PLoS Medicine
, 18
(11)
, Article e1003821. 10.1371/journal.pmed.1003821.
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Bhanu, Cini;
Petersen, Irene;
Orlu, Mine;
Davis, Daniel;
Sofat, Reecha;
Bazo-Alvarez, J;
Walters, Kate;
(2023)
Drug-induced Postural Hypotension: cluster analysis of co-prescription patterns in older people in UK primary care.
Pharmacoepidemiology & Drug Safety
, 33
(1)
, Article e5730. 10.1002/pds.5730.
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Bowles, BJ;
Dziemidowicz, K;
Lopez, FL;
Orlu, M;
Tuleu, C;
Edwards, AJ;
Ernest, TB;
(2018)
Co-Processed Excipients for Dispersible Tablets–Part 1: Manufacturability.
AAPS PharmSciTech
, 19
(6)
pp. 2598-2609.
10.1208/s12249-018-1090-4.
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Buanz, AB;
Belaunde, CC;
Soutari, N;
Tuleu, C;
Gul, MO;
Gaisford, S;
(2015)
Ink-jet printing versus solvent casting to prepare oral films: Effect on mechanical properties and physical stability.
International Journal of Pharmaceutics
, 494
(2)
pp. 611-618.
10.1016/j.ijpharm.2014.12.032.
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Bukhary, H;
Williams, GR;
Orlu, M;
(2020)
Fabrication of Electrospun Levodopa-Carbidopa Fixed-Dose Combinations.
Advanced Fiber Materials
10.1007/s42765-020-00031-1.
(In press).
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Bukhary, H;
Williams, GR;
Orlu, M;
(2018)
Electrospun fixed dose formulations of amlodipine besylate and valsartan.
International Journal of Pharmaceutics
, 549
(1-2)
pp. 446-455.
10.1016/j.ijpharm.2018.08.008.
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Bunc, M;
Hanning, SM;
Prieto Garcia, J;
Kristl, J;
Orlu, M;
(2019)
Characterisation of an in vitro aged cell culture model.
Farmacia
, 67
(2)
pp. 240-247.
10.31925/farmacia.2019.2.7.
|
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Burnand, Alice;
Kantilal, Kumud;
Woodward, Abi;
Bhanu, Cini;
Manthorpe, Jill;
Orlu, Mine;
Rait, Greta;
... Davies, Nathan; + view all
(2025)
Identifying risks in dementia care: Insights from a qualitative study with clinical pharmacists.
PLoS One
, 20
(6)
, Article e0325472. 10.1371/journal.pone.0325472.
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Burnand, Alice;
Woodward, Abi;
Kantilal, Kumud;
Bhanu, Cini;
Jani, Yogini;
Orlu, Mine;
Rait, Greta;
... Davies, Nathan; + view all
(2025)
Providing inclusive care and empowering people with dementia as a clinical pharmacist: a qualitative study of clinical pharmacist’s experiences.
Aging & Mental Health
, 29
(8)
pp. 1407-1413.
10.1080/13607863.2025.2481970.
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Burnand, Alice;
Woodward, Abi;
Kolodin, Vladimir;
Manthorpe, Jill;
Jani, Yogini;
Orlu, Mine;
Bhanu, Cini;
... Davies, Nathan; + view all
(2025)
Service delivery and the role of clinical pharmacists in UK primary care for older people, including people with dementia: a scoping review.
BMC Primary Care
, 26
, Article 10. 10.1186/s12875-024-02685-x.
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Clout, AE;
Della Pasqua, O;
Hanna, MG;
Orlu, M;
Pitceathly, RDS;
(2019)
Drug repurposing in neurological diseases: an integrated approach to reduce trial and error.
Journal of Neurology, Neurosurgery and Psychiatry
, 90
(11)
pp. 1270-1275.
10.1136/jnnp-2019-320879.
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Desai, Neel;
Maggioni, Emanuela;
Obrist, Marianna;
Orlu, Mine;
(2022)
Scent-delivery devices as a digital healthcare tool for olfactory training: A pilot focus group study in Parkinson's disease patients.
Digital Health
, 2022
, Article 8. 10.1177/20552076221129061.
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Desai, Neel;
Masen, Marc;
Cann, Philippa;
Hanson, Ben;
Tuleu, Catherine;
Orlu, Mine;
(2022)
Modernising Orodispersible Film Characterisation to Improve Palatability and Acceptability Using a Toolbox of Techniques.
Pharmaceutics
, 14
(4)
p. 732.
10.3390/pharmaceutics14040732.
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Desai, N;
Edwards, AJ;
Ernest, TB;
Tuleu, C;
Orlu, M;
(2020)
'Big Data' informed drug development: a case for acceptability.
Drug Discovery Today
10.1016/j.drudis.2020.12.011.
(In press).
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Desai, N;
Redfearn, A;
MacLeod, G;
Tuleu, C;
Hanson, B;
Orlu, M;
(2020)
How Do Orodispersible Tablets Behave in an In Vitro Oral Cavity Model: A Pilot Study.
Pharmaceutics
, 12
(7)
, Article 651. 10.3390/pharmaceutics12070651.
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Dizon, JIWT;
He, Q;
Shen, X;
Luk, P;
Chong, DYK;
Chan, KMK;
Chan, CWN;
... Ganotice, FA; + view all
(2024)
Which psychological needs profile exhibits higher engagement and favorable attitudes toward interprofessional education? A cluster analysis among health and social care Hong Kong students.
BMC Medical Education
, 24
(1)
, Article 1508. 10.1186/s12909-024-06507-7.
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Dou, L;
Gavins, FKH;
Mai, Y;
Madla, CM;
Taherali, F;
Orlu, M;
Murdan, S;
(2020)
Effect of Food and an Animal’s Sex on P-Glycoprotein Expression and Luminal Fluids in the Gastrointestinal Tract of Wistar Rats.
Pharmaceutics
, 12
(4)
, Article 296. 10.3390/pharmaceutics12040296.
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Dou, L;
Mai, Y;
Madla, CM;
Orlu, M;
Basit, AW;
(2018)
P-glycoprotein expression in the gastrointestinal tract of male and female rats is influenced differently by food.
European Journal of Pharmaceutical Sciences
, 123
pp. 569-575.
10.1016/j.ejps.2018.08.014.
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Dziemidowicz, K;
Lopez, FL;
Bowles, BJ;
Edwards, AJ;
Ernest, TB;
Orlu, M;
Tuleu, C;
(2018)
Co-Processed Excipients for Dispersible Tablets—Part 2: Patient Acceptability.
AAPS PharmSciTech
, 19
(6)
pp. 2646-2657.
10.1208/s12249-018-1104-2.
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Edirisinghe, S;
Raimi-Abraham, BT;
Gilmartin, JF-M;
Orlu-Gul, M;
(2015)
Multi-compartment compliance aids (MCAs): Application to the geriatric community.
European Geriatric Medicine
, 6
(1)
pp. 65-68.
10.1016/j.eurger.2014.05.004.
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Favaron, Alessia;
Abdalla, Youssef;
Basit, Abdul;
Orlu, Mine;
(2025)
Artificial Intelligence’s role in colon-targeted drug delivery.
Expert Opinion on Drug Delivery
10.1080/17425247.2025.2465769.
(In press).
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Favaron, Alessia;
Abdalla, Youssef;
McCoubrey, Laura E;
Nandiraju, Laxmi Prasanna;
Shorthouse, David;
Gaisford, Simon;
Basit, Abdul;
(2024)
Exploring the interactions of JAK inhibitor and S1P receptor modulator drugs with the human gut microbiome: Implications for colonic drug delivery and inflammatory bowel disease.
European Journal of Pharmaceutical Sciences
, 200
, Article 106845. 10.1016/j.ejps.2024.106845.
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Favaron, Alessia;
Sangfuang, Nannapat;
McCoubrey, Laura E;
Awad, Atheer;
Ghyselinck, Jonas;
Marzorati, Massimo;
Verstrepen, Lynn;
... Orlu, Mine; + view all
(2026)
Assessing the effects of tofacitinib on the gut microbiome in inflammatory bowel disease.
European Journal of Pharmaceutical Sciences
, 216
, Article 107365. 10.1016/j.ejps.2025.107365.
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Favaron, Alessia;
Turkgeldi, Engin;
Elbadawi, Moe;
Gaisford, Simon;
Basit, Abdul W;
Orlu, Mine;
(2024)
Do probiotic interventions improve female unexplained infertility? A critical commentary.
Reproductive BioMedicine Online
, 48
(4)
, Article 103734. 10.1016/j.rbmo.2023.103734.
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Fitaihi, Rawan;
Abukhamees, Shorooq;
Orlu, Mine;
Craig, Duncan QM;
(2023)
Transscleral Delivery of Dexamethasone-Loaded Microparticles Using a Dissolving Microneedle Array.
Pharmaceutics
, 15
(6)
, Article 1622. 10.3390/pharmaceutics15061622.
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Ganotice, Fraide A;
Tipoe, George L;
Orlu, Mine;
Tipoe, Eileen;
(2024)
Breaking disciplinary silos: A global approach to interprofessional education.
Medical Education
10.1111/medu.15342.
(In press).
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Gavins, FKH;
Dou, L;
Qin, Y;
Madla, CM;
Murdan, S;
Basit, AW;
Mai, Y;
(2023)
Prandial state and biological sex modulate clinically relevant efflux transporters to different extents in Wistar and Sprague Dawley rats.
Biomedicine and Pharmacotherapy
, 160
, Article 114329. 10.1016/j.biopha.2023.114329.
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Gavins, FKH;
Fu, Z;
Elbadawi, M;
Basit, AW;
Rodrigues, MRD;
Orlu, M;
(2022)
Machine Learning predicts the effect of food on orally administered medicines.
International Journal of Pharmaceutics
, 611
, Article 121329. 10.1016/j.ijpharm.2021.121329.
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Gerrard, SE;
Orlu-Gul, M;
Tuleu, C;
Slater, NK;
(2013)
Modeling the physiological factors that affect drug delivery from a nipple shield delivery system to breastfeeding infants.
Journal of Pharmaceutical Sciences
, 102
(10)
3773 - 3783.
10.1002/jps.23688.
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Gilmartin, JF;
Raimi-Abraham, BT;
Jani, Y;
Smith, F;
Orlu-Gul, M;
(2015)
Taking the guesswork out of supplying multicompartment compliance aids: do pharmacists require further guidance on medication stability?
International Journal of Pharmacy Practice
, 23
(5)
pp. 367-369.
10.1111/ijpp.12183.
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Gilmartin, JF-M;
Raimi-Abraham, BT;
Espadas-Garcia, I;
Gul, MO;
(2016)
Benefits of enhancing international mobility of pharmacy students.
The American Journal of Health-System Pharmacy
, 73
(15)
pp. 1128-1129.
10.2146/ajhp160261.
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Gilmartin-Thomas, J F-M;
Orlu, M;
Alsaeed, D;
Donovan, B;
(2017)
Using public engagement and consultation to inform the development of ageing-and dementia-friendly pharmacies – Innovative practice.
Dementia
10.1177/1471301217725896.
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Gul, MO;
Liu, F;
Hughes, C;
(2016)
Foreword: Special issue-geriatric drug therapy.
International Journal of Pharmaceutics
, 512
(2)
p. 331.
10.1016/j.ijpharm.2016.08.023.
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Hanning, SM;
Lopez, FL;
Wong, IC;
Ernest, TB;
Tuleu, C;
Orlu Gul, M;
(2016)
Patient centric formulations for paediatrics and geriatrics: Similarities and differences.
International Journal of Pharmaceutics
, 512
(2)
pp. 355-359.
10.1016/j.ijpharm.2016.03.017.
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Hanning, SM;
Muhamed, J;
Orlu-Gul, M;
(2015)
Investigation into the dosage form attributes of currently UK licensed cardiovascular and Parkinson's disease drug products.
International Journal of Pharmaceutics
, 479
(1)
159 - 162.
10.1016/j.ijpharm.2014.12.065.
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Hanning, SM;
Orlu Gul, M;
Toni, I;
Neubert, A;
Tuleu, C;
(2017)
A mini-review of non-parenteral clonidine preparations for paediatric sedation.
Journal of Pharmacy and Pharmacology
, 69
(4)
pp. 398-405.
10.1111/jphp.12662.
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Hanning, SM;
Orlu Gul, M;
Winslade, J;
Baarslag, MA;
Neubert, A;
Tuleu, C;
CloSed Consortium, .;
(2016)
Quality and clinical supply considerations of Paediatric Investigation Plans for IV preparations-A case study with the FP7 CloSed project.
International Journal of Pharmaceutics
, 511
(2)
pp. 1158-1162.
10.1016/j.ijpharm.2016.04.051.
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J M S Alsaeed, D;
Orlu Gul, M;
Smith, F;
(2016)
Understanding the challenges to optimal medicines use in people living with dementia and their caregivers.
International Journal of Pharmacy and Practice
, 24
(52)
pp. 33-60.
10.1111/ijpp.12279.
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Jani, YH;
Liu, F;
Orlu, M;
Desai, N;
Du Chayla, F;
Ruiz, F;
Vallet, T;
(2022)
Medicine acceptability for older people in hospital and care home: the influence of setting.
International Journal of Pharmacy Practice
, 30
(1)
pp. 67-74.
10.1093/ijpp/riab077.
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Januskaite, Patricija;
Goyanes, Alvaro;
Orlu, Mine;
Basit, Abdul W;
(2025)
Sex-specific formulations of doxazosin mesylate via direct powder extrusion 3D printing.
Drug Delivery and Translational Research
10.1007/s13346-025-01862-4.
(In press).
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Karimpoor, M;
Yebra-Fernandez, E;
Parhizkar, M;
Orlu, M;
Craig, D;
Khorashad, JS;
Edirisinghe, M;
(2018)
Alginate foam-based three-dimensional culture to investigate drug sensitivity in primary leukaemia cells.
Interface
, 15
(141)
10.1098/rsif.2017.0928.
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Keeley, A;
Teo, M;
Zarina, A;
John, F;
Manish, G;
Ali, R-S;
Orlu, M;
(2019)
In vitro dissolution model can predict the in vivo taste masking performance of coated multiparticulates.
Molecular Pharmaceutics
, 16
(5)
10.1021/acs.molpharmaceut.9b00060.
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Kucuk, I;
Ahmad, Z;
Edirisinghe, M;
Orlu-Gul, M;
(2014)
Utilization of microfluidic V-junction device to prepare surface itraconazole adsorbed nanospheres.
Int J Pharm
, 472
(1-2)
pp. 339-346.
10.1016/j.ijpharm.2014.06.023.
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Liu, F;
Ranmal, S;
Batchelor, HK;
Orlu-Gul, M;
Ernest, TB;
Thomas, IW;
Flanagan, T;
... Tuleu, C; + view all
(2015)
Formulation factors affecting acceptability of oral medicines in children.
International Journal of Pharmaceutics
, 492
(1-2)
pp. 341-343.
10.1016/j.ijpharm.2015.05.013.
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Liu, F;
Ranmal, S;
Batchelor, HK;
Orlu-Gul, M;
Ernest, TB;
Thomas, IW;
Flanagan, T;
(2014)
Patient-centred pharmaceutical design to improve acceptability of medicines: similarities and differences in paediatric and geriatric populations.
Drugs
, 74
(16)
1871 - 1889.
10.1007/s40265-014-0297-2.
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Lopez, F;
Mistry, P;
Batchelor, HK;
Bennett, J;
Coupe, A;
Ernest, TB;
Orlu, M;
(2018)
Acceptability of placebo multiparticulate formulations in children and adults.
Scientific Reports
, 8
, Article 9210. 10.1038/s41598-018-27446-6.
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Lopez, FL;
Bowles, A;
Gul, MO;
Clapham, D;
Ernest, TB;
Tuleu, C;
(2016)
Effect of formulation variables on oral grittiness and preferences of multiparticulate formulations in adult volunteers.
European Journal of Pharmaceutical Sciences
, 92
pp. 156-162.
10.1016/j.ejps.2016.07.006.
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Lopez, FL;
Ernest, TB;
Orlu, M;
Tuleu, C;
(2018)
The effect of administration media on palatability and ease of swallowing of multiparticulate formulations.
International Journal of Pharmacology
, 551
(1-2)
pp. 67-75.
10.1016/j.ijpharm.2018.08.021.
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Lopez, FL;
Ernest, TB;
Tuleu, C;
Gul, MO;
(2015)
Formulation approaches to pediatric oral drug delivery: benefits and limitations of current platforms.
Expert Opinion on Drug Delivery
, 12
(11)
pp. 1727-1740.
10.1517/17425247.2015.1060218.
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Madla, Christine M;
Qin, Yujia;
Gavins, Francesca KH;
Liu, Jing;
Dou, Liu;
Orlu, Mine;
Murdan, Sudaxshina;
... Basit, Abdul W; + view all
(2022)
Sex Differences in Intestinal P-glycoprotein Expression in Wistar versus Sprague Dawley Rats.
Pharmaceutics
, 14
(5)
, Article 1030. 10.3390/pharmaceutics14051030.
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Madla, CM;
Gavins, FKH;
Merchant, H;
Orlu, M;
Murdan, S;
Basit, AW;
(2021)
Let's talk about sex: Differences in drug therapy in males and females.
Advanced Drug Delivery Reviews
, 175
, Article 113804. 10.1016/j.addr.2021.05.014.
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Mai, Y;
Gavins, FKH;
Dou, L;
Liu,, J;
Taherali, F;
Alkahtani, ME;
Murdan, S;
... Orlu, M; + view all
(2021)
A non-nutritive feeding intervention alters the expression of efflux transporters in the gastrointestinal tract.
Pharmaceutics
, 13
(11)
, Article 1789. 10.3390/pharmaceutics13111789.
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Mai, Y;
Dou, L;
Yao, Z;
Madla, CM;
Gavins, FKH;
Taherali, F;
Yin, H;
... Basit, AW; + view all
(2021)
Quantification of P-Glycoprotein in the Gastrointestinal Tract of Humans and Rodents: Methodology, Gut Region, Sex, and Species Matter.
Molecular Pharmaceutics
, 18
pp. 1895-1904.
10.1021/acs.molpharmaceut.0c00574.
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Marconati, M;
Lopez, F;
Tuleu, C;
Orlu, M;
Ramaioli, M;
(2019)
In vitro and sensory tests to design easy-to-swallow multi-particulate formulations.
European Journal of Pharmaceutical Sciences
, 132
pp. 157-162.
10.1016/j.ejps.2019.02.026.
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McCoubrey, Laura E;
Shen, Chenghao;
Mwasambu, Sydney;
Favaron, Alessia;
Sangfuang, Nannapat;
Thomaidou, Stavrina;
Orlu, Mine;
... Basit, Abdul W; + view all
(2024)
Characterising and preventing the gut microbiota's inactivation of trifluridine, a colorectal cancer drug.
European Journal of Pharmaceutical Sciences
, 203
, Article 106922. 10.1016/j.ejps.2024.106922.
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McCoubrey, LE;
Ferraro, F;
Seegobin, N;
Verin, J;
Alfassam, HA;
Awad, A;
Marzorati, M;
... Basit, AW; + view all
(2024)
Poly(D,L-lactide-co-glycolide) particles are metabolised by the gut microbiome and elevate short chain fatty acids.
Journal of Controlled Release
, 369
pp. 163-178.
10.1016/j.jconrel.2024.03.039.
|
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McCoubrey, LE;
Gaisford, S;
Orlu, M;
Basit, AW;
(2022)
Predicting drug-microbiome interactions with machine learning.
Biotechnology Advdances
, 54
, Article 107797. 10.1016/j.biotechadv.2021.107797.
|
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McCoubrey, LE;
Seegobin, N;
Elbadawi, M;
Hu, Y;
Orlu, M;
Gaisford, S;
Basit, AW;
(2022)
Active Machine learning for formulation of precision probiotics.
International Journal of Pharmaceutics
, 616
, Article 121568. 10.1016/j.ijpharm.2022.121568.
|
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McCoubrey, LE;
Thomaidou, S;
Elbadawi, M;
Gaisford, S;
Orlu, M;
Basit, AW;
(2021)
Machine Learning Predicts Drug Metabolism and Bioaccumulation by Intestinal Microbiota.
Pharmaceutics
, 13
(12)
, Article 2001. 10.3390/pharmaceutics13122001.
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McCoubrey, LE;
Elbadawi, M;
Orlu, M;
Gaisford, S;
Basit, AW;
(2021)
Machine learning uncovers adverse drug effects on intestinal bacteria.
Pharmaceutics
, 13
(7)
, Article 1026. 10.3390/pharmaceutics13071026.
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McCoubrey, LE;
Elbadawi, M;
Orlu, M;
Gaisford, S;
Basit, AW;
(2021)
Harnessing machine learning for development of microbiome therapeutics.
Gut Microbes
, 13
(1)
pp. 1-20.
10.1080/19490976.2021.1872323.
|
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|
Merchant, HA;
Liu, F;
Gul, MO;
Basit, AW;
(2016)
Age-mediated changes in the gastrointestinal tract.
International Journal of Pharmaceutics
, 512
(2)
pp. 382-395.
10.1016/j.ijpharm.2016.04.024.
|
|
Mieiro, L;
Beuscart, J-B;
Knol, W;
Van Riet-Nales, D;
Orlu, M;
(2019)
Achieving Appropriate Medication for Older Adults: A Multidimensional Perspective.
Maturitas
, 124
pp. 43-47.
10.1016/j.maturitas.2019.03.007.
|
|
Nimmons, D;
Bhanu, C;
Orlu, M;
Schrag, A;
Walters, K;
(2021)
Orthostatic Hypotension and Antiparkinsonian Drugs: A Systematic Review and Meta-analysis.
Journal of Geriatric Psychiatry and Neurology
10.1177/08919887211060017.
(In press).
|
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O'Reilly, CS;
Elbadawi, M;
Desai, N;
Gaisford, S;
Basit, AW;
Orlu, M;
(2021)
Machine Learning and Machine Vision Accelerate 3D Printed Orodispersible Film Development.
Pharmaceutics
, 13
(12)
, Article 2187. 10.3390/pharmaceutics13122187.
|
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Orlu, M;
Goyanes, A;
Scarpa, M;
Kamlow, M;
Gaisford, S;
Basit, AW;
(2017)
Patient acceptability of 3D printed medicines.
International Journal of Pharmaceutics
, 530
(1-2)
pp. 71-78.
10.1016/j.ijpharm.2017.07.064.
|
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Orlu, M;
Ranmal, SR;
Sheng, Y;
Tuleu, C;
Seddon, P;
(2017)
Acceptability of orodispersible films for delivery of medicines to infants and preschool children.
Drug Delivery
, 24
(1)
pp. 1243-1248.
10.1080/10717544.2017.1370512.
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Pollard, TD;
Ong, JJ;
Goyanes, A;
Orlu, M;
Gaisford, S;
Elbadawi, M;
Basit, AW;
(2021)
Electrochemical biosensors: a nexus for precision medicine.
Drug Discovery Today
, 26
(1)
pp. 69-79.
10.1016/j.drudis.2020.10.021.
|
|
Raimi-Abraham, BT;
del Valle, AG;
Galcera, CV;
Barker, SA;
Orlu, M;
(2017)
Investigating the Physical Stability of Repackaged Medicine Stored into Commercially Available Multi-Compartment Compliance Aids (MCAs).
Journal of Pharmaceutical Health Services Research
, 8
(2)
pp. 81-89.
10.1111/jphs.12176.
|
|
Ranmal, SR;
O'Brien, F;
Lopez, F;
Ruiz, F;
Orlu, M;
Tuleu, C;
Walsh, J;
(2018)
Methodologies for assessing the acceptability of oral formulations among children and older adults: a systematic review.
Drug Discovery Today
, 23
(4)
pp. 830-847.
10.1016/j.drudis.2018.01.038.
|
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Redfearn, A;
Scarpa, M;
Orlu, M;
Hanson, B;
(2019)
In Vitro Oral Cavity Model for Screening the Disintegration Behavior of Orodispersible Films: A Bespoke Design.
Journal of Pharmaceutical Sciences
, 108
(5)
pp. 1831-1836.
10.1016/j.xphs.2018.12.025.
|
|
Ruiz, F;
Keeley, A;
Léglise, P;
Tuleu, C;
Lachuer, C;
Rwabihama, J-P;
Bachalat, N;
... Boudy, V; + view all
(2019)
Sex Differences in Medicine Acceptability: A New Factor to Be Considered in Medicine Formulation.
Pharmaceutics
, 11
(8)
, Article 368. 10.3390/pharmaceutics11080368.
|
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|
Scarpa, M;
Paudel, A;
Kloprogge, F;
Kai Hsiao, W;
Bresciani, M;
Gaisford, S;
Orlu, M;
(2018)
Key acceptability attributes of orodispersible films.
European Journal of Pharmaceutics and Biopharmaceutics
, 125
pp. 131-140.
10.1016/j.ejpb.2018.01.003.
|
|
Scarpa, M;
Stegemann, S;
Hsiao, W-K;
Pichler, H;
Gaisford, S;
Bresciani, M;
Paudel, A;
(2017)
Orodispersible Films: Towards Drug Delivery in Special Populations.
International Journal of Pharmaceutics
, 523
(1)
pp. 327-335.
10.1016/j.ijpharm.2017.03.018.
|
|
Shams, T;
Illangakoon, UE;
Parhizkar, M;
Harker, AH;
Edirisinghe, S;
Orlu, M;
Edirisinghe, M;
(2018)
Electrosprayed microparticles for intestinal delivery of prednisolone.
Journal of the Royal Society Interface
, 15
(145)
, Article 20180491. 10.1098/rsif.2018.0491.
|
|
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Shams, T;
Parhizkar, M;
Illangakoon, UE;
Orlu, M;
Edirisinghe, M;
(2017)
Core/shell microencapsulation of indomethacin/paracetamol by co-axial electrohydrodynamic atomization.
Materials & Design
, 136
pp. 204-213.
10.1016/j.matdes.2017.09.052.
|
|
|
Shen, Xiaoai;
Dizon, John Ian Wilzon T;
Chong, Yin Kei Doris;
He, Qing;
Fonseca, Gui;
Kwok, Tai On Tyrone;
Luk, Pauline;
... Ganotice, Fraide A; + view all
(2024)
Uncovering the factors underlying collaboration outcomes in interprofessional education: A preliminary investigation involving healthcare students.
Nurse Education Today
, 141
, Article 106325. 10.1016/j.nedt.2024.106325.
|
|
Sheng, Y;
Soto, J;
Orlu Gul, M;
Cortina-Borja, M;
Tuleu, C;
Standing, J;
(2016)
A New Generalized Poisson Mixture Model for Bimodal Count Data with Drug Effect: an application to Rodent Brief-Access Taste Aversion Experiments.
CPT: Pharmacometrics & Systems Pharmacology
, 5
(8)
pp. 427-436.
|
|
Smaje, A;
Weston-Clarke, M;
Raj, R;
Orlu, M;
Davis, DHJ;
Rawle, M;
(2018)
Factors associated with medication adherence in older patients: A systematic review.
Aging Medicine
, 1
(3)
pp. 254-266.
10.1002/agm2.12045.
|
|
Soto, J;
Ahmed, AM;
Turner, R;
Desset-Brethes, S;
Winzenburg, G;
Gul, MO;
Tuleu, C;
(2016)
Can solubilizing excipients be used with the rat BATA model to assess the taste of poorly water-soluble drugs?
International Journal of Pharmaceutics
, 511
(2)
p. 1148.
10.1016/j.ijpharm.2016.06.109.
|
|
Soto, J;
Keeley, A;
Keating, AV;
Mohamed-Ahmed, AHA;
Sheng, Y;
Winzenburg, G;
Turner, R;
... Tuleu, C; + view all
(2018)
Rats can predict aversiveness of Active Pharmaceutical Ingredients.
European Journal of Pharmaceutics and Biopharmaceutics
, 133
pp. 77-84.
10.1016/j.ejpb.2018.09.027.
|
|
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Soto, J;
Sheng, Y;
Standing, JF;
Orlu Gul, M;
Tuleu, C;
(2015)
Development of a model for robust and exploratory analysis of the rodent brief-access taste aversion data.
European Journal of Pharmaceutics and Biopharmaceutics
, 91
47 - 51.
10.1016/j.ejpb.2015.01.016.
|
|
Soto, J;
Winzenburg, G;
Turner, R;
Desset-Brethes, S;
Sheng, Y;
Orlu-Gul, M;
Tuleu, C;
(2016)
Assessing the bitter taste of medicines: A comparison between rat taste panels (via the brief-access taste aversion (BATA) model) and human taste panels.
International Journal of Pharmaceutics
, 511
(2)
pp. 1127-1128.
10.1016/j.ijpharm.2016.06.063.
|
|
Stillhart, C;
Vučićević, K;
Augustijns, P;
Basit, AW;
Batchelor, H;
Flanagan, TR;
Gesquiere, I;
... Müllertz, A; + view all
(2020)
Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review.
European Journal of Pharmaceutical Sciences
, 147
, Article 105280. 10.1016/j.ejps.2020.105280.
|
|
Sun, Siyuan;
Alkahtani, Manal E;
Gaisford, Simon;
Basit, Abdul W;
Elbadawi, Moe;
Orlu, Mine;
(2023)
Virtually Possible: Enhancing Quality Control of 3D-Printed Medicines with Machine Vision Trained on Photorealistic Images.
Pharmaceutics
, 15
(11)
, Article 2630. 10.3390/pharmaceutics15112630.
|
|
Tawfik, EA;
Scarpa, M;
Abdelhakim, HE;
Bukhary, HA;
Craig, DQM;
Barker, SA;
Orlu, M;
(2021)
A Potential Alternative Orodispersible Formulation to Prednisolone Sodium Phosphate Orally Disintegrating Tablets.
Pharmaceutics
, 13
(1)
, Article 120. 10.3390/pharmaceutics13010120.
|
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|
Tian, Y;
Orlu, M;
Woerdenbag, HJ;
Scarpa, M;
Kiefer, O;
Kottke, D;
Sjöholm, E;
... Visser, JC; + view all
(2019)
Oromucosal films: from patient centricity to production by printing techniques.
Expert Opinion on Drug Delivery
, 16
(9)
pp. 981-993.
10.1080/17425247.2019.1652595.
|
|
Timmis, J;
Orlu, M;
Park, S;
(2018)
Educational potential of using virtual patients for promoting interprofessional learning between medical and pharmacy students: A qualitative study.
Journal of Interprofessional Care
10.1080/13561820.2018.1513461.
(In press).
|
|
Tuleu, C;
Hanning, SM;
Orlu, M;
Krasser, K;
Matiz, S;
Dodoo, C;
Gaisford, S;
(2020)
Characterisation of rectal amoxicillin (RAMOX) for the treatment of pneumonia in children.
Drug Delivery and Translational Research
10.1007/s13346-020-00804-6.
(In press).
|
|
|
Vallet, T;
Michelon, H;
Orlu, M;
Jani, Y;
Leglise, P;
Laribe-Caget, S;
Piccoli, M;
... Boudy, V; + view all
(2020)
Acceptability in the Older Population: The Importance of an Appropriate Tablet Size.
Pharmaceutics
, 12
(8)
, Article 746. 10.3390/pharmaceutics12080746.
|
|
|
Visser, JC;
Wibier, L;
Kiefer, O;
Orlu, M;
Breitkreutz, J;
Woerdenbag, HJ;
Taxis, K;
(2020)
A Pediatrics Utilization Study in The Netherlands to Identify Active Pharmaceutical Ingredients Suitable for Inkjet Printing on Orodispersible Films.
Pharmaceutics
, 12
(2)
, Article 164. 10.3390/pharmaceutics12020164.
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|
|
Wahlich, J;
Elder, D;
Liu, F;
Hughes, C;
Orlu-Gul, M;
(2015)
Meeting commentary–"Parkinson's disease: From patient to product".
International Journal of Pharmaceutics
, 494
(1)
pp. 167-171.
10.1016/j.ijpharm.2015.07.074.
|
|
Wahlich, J;
Orlu, M;
Mair, A;
Stegemann, S;
van Riet-Nales, D;
(2019)
Age-Related Medicine.
Pharmaceutics
, 11
(4)
10.3390/pharmaceutics11040172.
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|
|
Wan, M;
Orlu-Gul, M;
Legay, H;
Tuleu, C;
(2013)
Blinding in pharmacological trials: the devil is in the details.
Archives of Disease in Childhood
, 98
(9)
pp. 656-659.
10.1136/archdischild-2013-304037.
|
|
|
Zhao, L;
Orlu, M;
Williams, GR;
(2021)
Electrospun fixed dose combination fibers for the treatment of cardiovascular disease.
International Journal of Pharmaceutics
, 599
, Article 120426. 10.1016/j.ijpharm.2021.120426.
|
|
ZHI, Zhuo;
Elbadawi, Moe;
Daneshmend, Adam;
Orlu, Mine;
Basit, Abdul;
Demosthenous, Andreas;
Rodrigues, Miguel;
(2024)
HgbNet: predicting hemoglobin level/anemia degree from irregular EHR.
IEEE Access
p. 1.
10.1109/access.2024.3473693.
(In press).
|
|
|
Zhi, Zhuo;
Liu, Ziquan;
Elbadawi, Moe;
Daneshmend, Adam;
Orlu, Mine;
Basit, Abdul;
Demosthenous, Andreas;
(2025)
Borrowing treasures from neighbors: In-context learning for multimodal learning with missing modalities and data scarcity.
Neurocomputing
, 647
, Article 130502. 10.1016/j.neucom.2025.130502.
|
|
Book chapter
|
McCoubrey, Laura;
Batchelor, Hannah;
Basit, Abdul;
Gaisford, Simon;
Orlu, Mine;
(2022)
Impact of the Microbiome on Oral Biopharmaceutics.
In: Batchelor, Hannah, (ed.)
Biopharmaceutics: From Fundamentals to Industrial Practice.
(pp. 277-295).
Wiley
|
|
Orlu, M;
Salunke, S;
Tuleu, C;
(2018)
Paediatric Pharmaceutics—The Science of Formulating Medicines for Children.
In: Tovey, GD, (ed.)
Pharmaceutical Formulation: The Science and Technology of Dosage Forms.
(pp. 258-287).
Royal Society of Chemistry: Cambridge, UK.
|
Poster
|
Scarpa, M;
Redfearn, A;
Hanson, B;
Orlu, M;
(2018)
Novel approach to disintegration testing of orodispersible films: in vitro oral cavity simulator.
Presented at: 10th EuPFI Conference, London, UK.
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|
Thesis
|
Alsaeed, Dalal JMS;
(2018)
Optimising medication use for people living with dementia and their caregivers.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Bukhary, Haitham Abdulrahim;
(2019)
Developing fixed dose combinations for the geriatric population.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Keeley, Alexander Joseph;
(2019)
Enhancing the understanding of palatability assessment used in the development of paediatric medicines.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Lopez Lopez, Felipe;
(2017)
Better medicines for children; elucidating patient acceptability to guide flexible solid oral dosage form design.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Scarpa, Mariagiovanna;
(2019)
Defining end-user acceptability attributes of orodispersible films for patient centricity.
Doctoral thesis (Ph.D), UCL (University College London).
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