Liu, F;
Ranmal, S;
Batchelor, HK;
Orlu-Gul, M;
Ernest, TB;
Thomas, IW;
Flanagan, T;
(2014)
Patient-centred pharmaceutical design to improve acceptability of medicines: similarities and differences in paediatric and geriatric populations.
Drugs
, 74
(16)
1871 - 1889.
10.1007/s40265-014-0297-2.
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Abstract
Patient acceptability of a medicinal product is a key aspect in the development and prescribing of medicines. Children and older adults differ in many aspects from the other age subsets of population and require particular considerations in medication acceptability. This review highlights the similarities and differences in these two age groups in relation to factors affecting acceptability of medicines. New and conventional formulations of medicines are considered regarding their appropriateness for use in children and older people. Aspects of a formulation that impact acceptability in these patient groups are discussed, including, for example, taste/smell/viscosity of a liquid and size/shape of a tablet. A better understanding of the acceptability of existing formulations highlights opportunities for the development of new and more acceptable medicines and facilitates safe and effective prescribing for the young and older populations.
Type: | Article |
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Title: | Patient-centred pharmaceutical design to improve acceptability of medicines: similarities and differences in paediatric and geriatric populations |
Location: | New Zealand |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1007/s40265-014-0297-2 |
Publisher version: | http://dx.doi.org/10.1007/s40265-014-0297-2 |
Language: | English |
Additional information: | This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. https://creativecommons.org/licenses/by-nc/3.0/ |
Keywords: | Dosage Form, Oropharyngeal Dysphagia, Solid Dosage Form, Sour Taste, Chewable Tablet |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharmaceutics |
URI: | https://discovery.ucl.ac.uk/id/eprint/1451141 |
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