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Article

(2015) Contralateral cerebello-thalamo-cortical pathways with prominent involvement of associative areas in humans in vivo. Brain Structure and Function , 220 (6) pp. 3369-3384. 10.1007/s00429-014-0861-2. Green open access
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Al-Araji, Sarmad; Moccia, Marcello; Jha, Ashwani; Zhang, Le; Eshaghi, Arman; Kanber, Baris; Bianchi, Alessia; ... Ciccarelli, Olga; + view all (2025) Effectiveness of Disease-Modifying Therapies in Patients With Late-Onset Relapsing-Remitting Multiple Sclerosis. Neurology , 105 (4) , Article e213967. 10.1212/WNL.000000000021396. Green open access
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Almouzain, L; Stevenson, F; Chard, D; Rahman, NA; Hamilton, F; (2021) Switching treatments in clinically stable relapsing remitting multiple sclerosis patients planning for pregnancy. Multiple Sclerosis Journal - Experimental, Translational and Clinical , 7 (1) 10.1177/20552173211001571. Green open access
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Ananthavarathan, Piriyankan; Sahi, Nitin; Chung, Karen; Haider, Lukas; Prados, Ferran; Trip, S Anand; Ciccarelli, Olga; ... Chard, Declan T; + view all (2024) The evolving contribution of MRI measures towards the prediction of secondary progressive multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry 10.1136/jnnp-2024-333917. Green open access
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Baheerathan, A; Brownlee, WJ; Chard, DT; Shields, K; Gregory, R; Trip, SA; (2017) Antecedent anti-NMDA receptor encephalitis in two patients with multiple sclerosis. Multiple Sclerosis and Related Disorders , 12 pp. 20-22. 10.1016/j.msard.2016.12.009. Green open access
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Baheerathan, A; Brownlee, WJ; Rugg-Gunn, F; Chard, DT; Trip, SA; (2017) Neuromyelitis optica spectrum disorder related tonic spasms responsive to lacosamide. Multiple Sclerosis and Related Disorders , 13 pp. 73-74. 10.1016/j.msard.2017.02.009. Green open access
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Bodini, B; Chard, D; Altmann, DR; Tozer, D; Miller, DH; Thompson, AJ; Wheeler-Kingshott, CAM; (2015) White and grey matter damage in primary-progressive MS: the chicken or the egg? Neurology , 86 (2) pp. 170-176. 10.​1212/​WNL.​0000000000002237. Green open access
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Bouman, Piet M; Noteboom, Samantha; Nobrega Santos, Fernando A; Beck, Erin S; Bliault, Gregory; Castellaro, Marco; Calabrese, Massimiliano; ... Steenwijk, Martijn D; + view all (2023) Multicenter Evaluation of AI-generated DIR and PSIR for Cortical and Juxtacortical Multiple Sclerosis Lesion Detection. Radiology , 307 (2) , Article 221425. 10.1148/radiol.221425. Green open access
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Brown, J William L; Prados, Ferran; Altmann, Daniel R; Kanber, Baris; Stutters, Jonathan; Cunniffe, Nick G; Jones, Joanne L; ... Chard, Declan; + view all (2022) Remyelination varies between and within lesions in multiple sclerosis following bexarotene. Annals of Clinical and Translational Neurology , 9 (10) pp. 1626-1642. 10.1002/acn3.51662. Green open access
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Brown, J William L; Prados Carrasco, F; Eshaghi, A; Sudre, CH; Button, T; Pardini, M; Samson, RS; ... Chard, DT; + view all (2020) Periventricular magnetisation transfer ratio abnormalities in multiple sclerosis improve after alemtuzumab. Multiple Sclerosis Journal , 26 (9) 1093 -1101. 10.1177/1352458519852093. Green open access
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Brown, JWL; Cunniffe, NG; Prados, F; Kanber, B; Jones, JL; Needham, E; Georgieva, Z; ... Coles, AJ; + view all (2021) Safety and efficacy of bexarotene in patients with relapsing-remitting multiple sclerosis (CCMR One): a randomised, double-blind, placebo-controlled, parallel-group, phase 2a study. The Lancet Neurology , 20 (9) pp. 709-720. 10.1016/S1474-4422(21)00179-4. Green open access
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Brown, W; Chowdhury, A; Kanber, B; Prados Carrasco, F; Eshaghi, A; Sudre, CH; Pardini, M; ... Chard, DT; + view all (2019) Magnetisation transfer ratio abnormalities in primary and secondary progressive multiple sclerosis. Multiple Sclerosis Journal (In press). Green open access
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Brown, WL; Pardini, M; Brownlee, WJ; Fernando, K; Samson, R; Prados Carrasco, F; Ourselin, S; ... Chard, DT; + view all (2016) An abnormal periventricular magnetisation transfer ratio gradient occurs early in multiple sclerosis. Brain , 140 (2) pp. 387-398. 10.1093/brain/aww296. Green open access
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Calvi, Alberto; Carrasco, Ferran Prados; Tur, Carmen; Chard, Declan T; Stutters, Jonathan; De Angelis, Floriana; John, Nevin; ... MSSMART Investigators, .; + view all (2022) Association of Slowly Expanding Lesions on MRI With Disability in People With Secondary Progressive Multiple Sclerosis. Neurology , 98 (17) e1783-e1793. 10.1212/WNL.0000000000200144. Green open access
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Calvi, Alberto; Mendelsohn, Zoe; Hamed, Weaam; Chard, Declan; Tur, Carmen; Stutters, Jon; MacManus, David; ... Prados, Ferran; + view all (2023) Treatment reduces the incidence of newly appearing multiple sclerosis lesions evolving into chronic active, slowly expanding lesions: A retrospective analysis. European Journal of Neurology 10.1111/ene.16092. (In press). Green open access
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Calvi, Alberto; Tur, Carmen; Chard, Declan; Stutters, Jonathan; Ciccarelli, Olga; Cortese, Rosa; Battaglini, Marco; ... Barkhof, Frederik; + view all (2022) Slowly expanding lesions relate to persisting black-holes and clinical outcomes in relapse-onset multiple sclerosis. NeuroImage: Clinical , 35 , Article 103048. 10.1016/j.nicl.2022.103048. Green open access
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Calvi, A; Haider, L; Prados, F; Tur, C; Chard, D; Barkhof, F; (2020) In vivo imaging of chronic active lesions in multiple sclerosis. Multiple Sclerosis Journal 10.1177/1352458520958589. (In press). Green open access
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Charalambous, T; Clayden, JD; Powell, E; Prados, F; Tur, C; Kanber, B; Chard, D; ... Toosy, AT; + view all (2020) Disrupted principal network organisation in multiple sclerosis relates to disability. Scientific Reports , 10 , Article 3620. 10.1038/s41598-020-60611-4. Green open access
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Charalambous, T; Tur, C; Prados, F; Kanber, B; Chard, DT; Ourselin, S; Clayden, JD; ... Toosy, AT; + view all (2019) Structural network disruption markers explain disability in multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry , 90 (2) pp. 219-226. 10.1136/jnnp-2018-318440. Green open access
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Chard, Declan T; (2024) A memoir of multiple sclerosis Stephen L Hauser, The Face Laughs While the Brain Cries: The Education of a Doctor, St Martin's Press (2023), p. 304, £24·99, ISBN: 978-1-250-28389-4. [Review]. The Lancet Neurology , 23 (1) p. 35. 10.1016/S1474-4422(23)00474-X. Green open access
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Chard, D; (2016) Brain atrophy measurements should be used to guide therapy monitoring in MS - Commentary. Multiple Sclerosis Journal , 22 (12) pp. 1526-1527. 10.1177/1352458516656061. Green open access
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Chard, D; Trip, A; Chataway, J; (2016) New oral drugs for the treatment of multiple sclerosis. British Journal of Hospital Medicine , 77 (9) pp. 502-503. 10.12968/hmed.2016.77.9.502. Green open access
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Chard, D; Trip, SA; (2019) An asymptomatic new lesion on MRI is a relapse and should be treated accordingly - No. Multiple Sclerosis , 25 (14) pp. 1843-1845. 10.1177/1352458519845111. Green open access
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Chard, D; Trip, SA; (2017) Resolving the clinico-radiological paradox in multiple sclerosis. F1000Research , 6 , Article 1828. 10.12688/f1000research.11932.1. Green open access
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Chard, DT; (2019) Commentary on Al Hussona et al. 'New-onset seizures as a sole clinical presentation of multiple sclerosis'. Multiple Sclerosis Journal , 25 (2) pp. 298-299. 10.1177/1352458518781978. Green open access
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Chard, DT; Alahmadi, AAS; Audoin, B; Charalambous, T; Enzinger, C; Hulst, HE; Rocca, MA; ... MAGNIMS Study Group, .; + view all (2021) Mind the gap: from neurons to networks to outcomes in multiple sclerosis. Nature Reviews Neurology , 17 pp. 173-184. 10.1038/s41582-020-00439-8. Green open access
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Chard, DT; Miller, DH; (2016) What lies beneath grey matter atrophy in multiple sclerosis? [Editorial comment]. Brain , 139 (Pt 1) pp. 7-10. 10.1093/brain/awv354. Green open access
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Chard, DT; Miller, DH; (2009) What you see depends on how you look Gray matter lesions in multiple sclerosis. [Editorial comment]. Neurology , 73 (12) 918 - 919. 10.1212/WNL.0b013e3181b99a1e.

Christensen, Ronja; Cruciani, Alessandro; Al-Araji, Sarmad; Bianchi, Alessia; Chard, Declan; Fourali, Samih; Hamed, Weaam; ... Ciccarelli, Olga; + view all (2025) Single-centre, prospective cohort to predict optimal individualised treatment response in multiple sclerosis (POINT-MS): a cohort profile. BMJ Open , 15 (9) , Article e103440. 10.1136/bmjopen-2025-103440. Green open access
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Chung, KK; Altmann, D; Barkhof, F; Miszkiel, K; Brex, PA; O'Riordan, J; Ebner, M; ... Chard, DT; + view all (2020) A thirty year clinical and MRI observational study of multiple sclerosis and clinically isolated syndromes. Annals of Neurology , 87 (1) pp. 63-74. 10.1002/ana.25637. Green open access
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Ciccarelli, O; Thomas, DL; DeVita, E; Wheeler-Kingshott, CAM; Kachramanoglou, C; Kapoor, R; Leary, S; ... Thompson, AJ; + view all (2013) Low Myo‐inositol indicating astrocytic damage in a case series of neuromyelitis optica. Annals of Neurology , 74 (2) pp. 301-305. 10.1002/ana.23909. Green open access
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Colato, Elisa; Prados, Ferran; Stutters, Jonathan; Bianchi, Alessia; Narayanan, Sridar; Arnold, Douglas L; Wheeler-Kingshott, Claudia; ... Eshaghi, Arman; + view all (2023) Networks of microstructural damage predict disability in multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry pp. 1-12. 10.1136/jnnp-2022-330203. Green open access
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Colato, Elisa; Stutters, Jonathan; Narayanan, Sridar; Arnold, Douglas L; Chataway, Jeremy; Wheeler-Kingshott, Claudia AM Gandini; Barkhof, Frederik; ... Chard, Declan T; + view all (2024) Longitudinal network-based brain grey matter MRI measures are clinically relevant and sensitive to treatment effects in multiple sclerosis. Brain Communications , 6 (4) , Article fcae234. 10.1093/braincomms/fcae234. Green open access
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Colato, E; Stutters, J; Tur, C; Narayanan, S; Arnold, DL; Gandini Wheeler-Kingshott, CAM; Barkhof, F; ... Eshaghi, A; + view all (2021) Predicting disability progression and cognitive worsening in multiple sclerosis using patterns of grey matter volumes. Journal of Neurology, Neurosurgery & Psychiatry 10.1136/jnnp-2020-325610. (In press). Green open access
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Cole, JH; Raffel, J; Friede, T; Eshaghi, A; Brownlee, WJ; Chard, D; De Stefano, N; ... MAGNIMS study group; + view all (2020) Longitudinal assessment of multiple sclerosis with the brain-age paradigm. Annals of Neurology , 88 (1) pp. 93-105. 10.1002/ana.25746. Green open access
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De Angelis, F; Brownlee, WJ; Chard, DT; Trip, SA; (2019) New MS diagnostic criteria in practice. Practical Neurology , 19 (1) 10.1136/practneurol-2018-001945. Green open access
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De Meo, Ermelinda; Carrasco, Ferran Prados; Brown, J William L; Coles, Alasdair J; Cunniffe, Nick G; Jolly, Amy E; Kanber, Baris; ... Chard, Declan; + view all (2025) An MRI assessment of mechanisms underlying lesion growth and shrinkage in multiple sclerosis. Annals of Clinical and Translational Neurology , 12 (4) pp. 686-700. 10.1002/acn3.52308. Green open access
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De Meo, Ermelinda; Nistri, Riccardo; Eyre, Michael; Hemingway, Cheryl; Lim, Ming; Rossor, Thomas; Biswas, Asthik; ... Hacohen, Yael; + view all (2025) Understanding Mechanisms of Whole Brain and Regional Grey Matter Atrophy in Children With MOGAD. Annals of Clinical and Translational Neurology 10.1002/acn3.70123. (In press). Green open access
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Dobson, R; Ramagopalan, S; Topping, J; Smith, P; Solanky, B; Schmierer, K; Chard, D; (2016) A Risk Score for Predicting Multiple Sclerosis. PLoS ONE , 11 (11) , Article e0164992. 10.1371/journal.pone.0164992. Green open access
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Ebner, M; Chung, K; Prados Carrasco, F; Cardoso, MJ; Chard, DT; Vercauteren, T; Ourselin, S; (2017) Volumetric reconstruction from printed films: Enabling 30 year longitudinal analysis in MR neuroimaging. NeuroImage 10.1016/j.neuroimage.2017.09.056. (In press). Green open access
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Engels, K; Schiffmann, I; Weierstall, R; Rahn, AC; Daubmann, A; Pust, G; Chard, D; ... Heesen, C; + view all (2019) Emotions towards magnetic resonance imaging in people with multiple sclerosis. Acta Neurologica Scandinavica , 139 (6) pp. 497-504. 10.1111/ane.13082. Green open access
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Eshaghi, A; Marinescu, RV; Young, AL; Firth, NC; Prados Carrasco, F; Cardoso, MJ; Tur Gomez, C; ... MAGNIMS Study Group, .; + view all (2018) Progression of regional grey matter atrophy in multiple sclerosis. Brain , 141 (6) pp. 1665-1677. 10.1093/brain/awy088. Green open access
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Eshaghi, A; Prados Carrasco, F; Brownlee, W; Altmann, DR; Tur Gomez, C; Cardoso, MJ; de Angelis, F; ... Ciccarelli, O; + view all (2018) Deep grey matter volume loss drives disability worsening in multiple sclerosis. Annals of Neurology , 83 (2) pp. 210-222. 10.1002/ana.25145. Green open access
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Eshaghi, A; Young, A; Wijeratne, PA; Prados, F; Arnold, DL; Narayanan, S; Guttmann, CRG; ... Ciccarelli, O; + view all (2021) Identifying multiple sclerosis subtypes using unsupervised machine learning and MRI data. Nature Communications , 12 , Article 2078. 10.1038/s41467-021-22265-2. Green open access
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Filippi, M; Bruck, W; Chard, D; Fazekas, F; Geurts, JJG; Enzinger, C; Hametner, S; ... Rocca, MA; + view all (2019) Association between pathological and MRI findings in multiple sclerosis. Lancet Neurology , 18 (2) pp. 198-210. 10.1016/S1474-4422(18)30451-4. Green open access
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Filippi, M; Preziosa, P; Barkhof, F; Chard, DT; De Stefano, N; Fox, RJ; Gasperini, C; ... Rocca, MA; + view all (2020) Diagnosis of Progressive Multiple Sclerosis From the Imaging Perspective: A Review. JAMA Neurology 10.1001/jamaneurol.2020.4689. (In press).

Freund, Magalie; Schiffmann, Insa; Rahn, Anne Christin; Chard, Declan; Lukas, Carsten; Scheiderbauer, Jutta; Sippel, Anna; (2022) Understanding Magnetic Resonance Imaging in Multiple Sclerosis (UMIMS): Development and Piloting of an Online Education Program About Magnetic Resonance Imaging for People With Multiple Sclerosis. Frontiers in Neurology , 13 , Article 856240. 10.3389/fneur.2022.856240. Green open access
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Geraldes, Ruth; Arrambide, Georgina; Banwell, Brenda; Rovira, Àlex; Cortese, Rosa; Lassmann, Hans; Messina, Silvia; ... MAGNIMS Study Group; + view all (2024) The influence of MOGAD on diagnosis of multiple sclerosis using MRI. Nature Reviews Neurology , 20 pp. 620-635. 10.1038/s41582-024-01005-2. Green open access
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Geraldes, R; Juryńczyk, M; Dos Passos, G; Prichler, A; Chung, K; Hagens, M; Ruggieri, S; ... MAGNIMS study group; + view all (2020) Distinct influence of different vascular risk factors on white matter brain lesions in multiple sclerosis. Journal of Neurology, Neurosurgery & Psychiatry , 91 (4) pp. 388-391. 10.1136/jnnp-2019-322369. Green open access
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Geraldes, R; Juryńczyk, M; Dos Passos, GR; Pichler, A; Chung, K; Hagens, M; Ruggieri, S; ... MAGNIMS study group, .; + view all (2020) The role of pontine lesion location in differentiating multiple sclerosis from vascular risk factor-related small vessel disease. Multiple Sclerosis Journal 10.1177/1352458520943777. (In press). Green open access
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Geurts, JJ; Chard, DT; (2016) Visualization of cortical MS lesions with MRI need not be further improved - YES. Multiple Sclerosis , 23 (1) 10.1177/1352458516665498. Green open access
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Goebl, Philipp; Wingrove, Jed; Abdelmannan, Omar; Brito Vega, Barbara; Stutters, Jonathan; Ramos, Silvia Da Graca; Kenway, Owain; ... Eshaghi, Arman; + view all (2025) Enabling new insights from old scans by repurposing clinical MRI archives for multiple sclerosis research. Nature Communications , 16 , Article 3149. 10.1038/s41467-025-58274-8. Green open access
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Haider, Lukas; Chung, Karen K; Mangesius, Stephanie; Furtner, Julia; Ciccarelli, Olga; Chard, Declan T; Barkhof, Frederik; (2023) The relation of sarcopenia and disability in multiple sclerosis. Multiple Sclerosis and Related Disorders , 77 , Article 104855. 10.1016/j.msard.2023.104855. Green open access
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Haider, L; Chung, KK; Birch, G; Eshaghi, A; Mangesius, S; Prados Carrasco, F; Tur Gomez, C; ... Chard, DT; + view all (2021) Linear brain atrophy measures in multiple sclerosis and clinically isolated syndromes: A 30-year follow-up. Journal of Neurology, Neurosurgery & Psychiatry , 92 (8) pp. 839-846. 10.1136/jnnp-2020-325421. Green open access
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Haider, L; Prados Carrasco, F; Chung, K; Goodkin, O; Kanber, B; Sudre, C; Yiannakas, M; ... Barkhof, F; + view all (2021) Cortical involvement determines impairment 30 years after a clinically isolated syndrome. Brain , 144 (5) pp. 1384-1395. 10.1093/brain/awab033. Green open access
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Kearney, H; Rocca, M; Valsasina, P; Balk, L; Sastre-Garriga, J; Reinhardt, J; Ruggieri, S; ... Chard, D; + view all (2014) Magnetic resonance imaging correlates of physical disability in relapse onset multiple sclerosis of long disease duration. Mult Scler , 20 (1) pp. 72-80. 10.1177/1352458513492245. Green open access
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Lageman, Senne B; Jolly, Amy; Sahi, Nitin; Prados, Ferran; Kanber, Baris; Eshaghi, Arman; Tur, Carmen; ... Chard, Declan T; + view all (2025) Explaining cognitive function in multiple sclerosis through networks of grey and white matter features: a joint independent component analysis. Journal of Neurology , 272 (2) , Article 142. 10.1007/s00415-024-12795-2. Green open access
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Lehnert, Thomas; Röver, Christian; Köpke, Sascha; Rio, Jordi; Chard, Declan; Fittipaldo, Andrea V; Friede, Tim; ... Rahn, Anne C; + view all (2022) Immunotherapy for people with clinically isolated syndrome or relapsing-remitting multiple sclerosis: treatment response by demographic, clinical, and biomarker subgroups (PROMISE)—a systematic review protocol. Systematic Reviews , 11 , Article 134. 10.1186/s13643-022-01997-2. Green open access
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Liu, Z; Pardini, M; Yaldizli, Ö; Sethi, V; Muhlert, N; Wheeler-Kingshott, CA; Samson, RS; ... Chard, DT; + view all (2015) Magnetization transfer ratio measures in normal-appearing white matter show periventricular gradient abnormalities in multiple sclerosis. Brain , 138 (5) pp. 1239-1246. 10.1093/brain/awv065. Green open access
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Liu, Z; Pardini, M; Yaldizli, O; Sethi, V; Muhlert, N; Wheeler-Kingshott, CAM; Samson, RS; ... Chard, DT; + view all (2015) Magnetisation transfer ratio measures in normal appearing white matter show periventricular gradient abnormalities in multiple sclerosis. Brain , 138 (5) pp. 1239-1246. 10.1093/brain/awv065. Green open access
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Mallik, S; Muhlert, N; Samson, RS; Sethi, V; Wheeler-Kingshott, CA; Miller, DH; Chard, DT; (2015) Regional patterns of grey matter atrophy and magnetisation transfer ratio abnormalities in multiple sclerosis clinical subgroups: A voxel-based analysis study. Mult Scler , 21 (4) 423 - 432. 10.1177/1352458514546513. Green open access
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Mcmurran, Christopher E; De Meo, Ermelinda; Cunniffe, Nick G; Brown, J William L; Prados, Ferran; Kanber, Baris; Cole, James H; ... Chard, Declan T; + view all (2025) Exploratory analysis of biological age measures in a remyelination clinical trial. Brain Communications , 7 (1) , Article fcaf032. 10.1093/braincomms/fcaf032. Green open access
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McMurran, Christopher E; Mukherjee, Trisha; Brown, J William L; Michell, Andrew W; Chard, Declan T; Franklin, Robin JM; Coles, Alasdair J; (2022) Remyelination in humans due to a retinoid-X receptor agonist is age-dependent. Annals of Clinical and Translational Neurology , 9 (7) pp. 1090-1094. 10.1002/acn3.51595. Green open access
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Meijer, KA; Cercignani, M; Muhlert, N; Sethi, V; Chard, D; Geurts, JJG; Ciccarelli, O; (2016) Patterns of white matter damage are non-random and associated with cognitive function in secondary progressive multiple sclerosis. NeuroImage: Clinical , 12 pp. 123-131. 10.1016/j.nicl.2016.06.009. Green open access
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Muhlert, N; Sethi, V; Cipolotti, L; Haroon, H; Parker, GJ; Yousry, T; Wheeler-Kingshott, C; ... Chard, D; + view all (2015) The grey matter correlates of impaired decision-making in multiple sclerosis. Journal of Neurology, Neurosurgery & Psychiatry , 86 (5) pp. 530-536. 10.1136/jnnp-2014-308169. Green open access
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Palesi, F; De Rinaldis, A; Castellazzi, G; Calamante, F; Muhlert, N; Chard, D; Tournier, JD; ... Wheeler-Kingshott, CAM; + view all (2017) Contralateral cortico-ponto-cerebellar pathways reconstruction in humans in vivo: implications for reciprocal cerebro-cerebellar structural connectivity in motor and non-motor areas. Scientific Reports , 7 , Article 12841. 10.1038/s41598-017-13079-8. Green open access
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Palesi, F; Tournier, JD; Calamante, F; Muhlert, N; Castellazzi, G; Chard, D; D'Angelo, E; (2016) Reconstructing contralateral fiber tracts: methodological aspects of cerebello-thalamocortical pathway reconstruction. Functional Neurology , 31 (4) pp. 229-238. 10.11138/FNeur/2016.31.4.229. Green open access
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Pardini, M; Brown, JWL; Magliozzi, R; Reynolds, R; Chard, DT; (2021) Surface-in pathology in multiple sclerosis: a new view on pathogenesis? Brain , 144 (6) pp. 1646-1654. 10.1093/brain/awab025. Green open access
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Pardini, M; Petracca, M; Harel, A; Fleysher, L; Oesingmann, N; Bommarito, G; Fabian, M; ... Inglese, M; + view all (2017) The relationship between cortical lesions and periventricular NAWM abnormalities suggests a shared mechanism of injury in primary-progressive MS. NeuroImage: Clinical , 16 pp. 111-115. 10.1016/j.nicl.2017.07.001. Green open access
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Pardini, M; Sudre, CH; Prados, F; Yaldizli, Ö; Sethi, V; Muhlert, N; Samson, RS; ... Chard, DT; + view all (2016) Relationship of grey and white matter abnormalities with distance from the surface of the brain in multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry , 87 (11) pp. 1212-1217. 10.1136/jnnp-2016-313979. Green open access
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Rahn, AC; Köpke, S; Stellmann, J-P; Schiffmann, I; Lukas, C; Chard, D; Heesen, C; (2019) Magnetic resonance imaging as a prognostic disability marker in clinically isolated syndrome: A systematic review. [Review]. Acta Neurologica Scandinavica , 139 (1) 18 -32. 10.1111/ane.13010. Green open access
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Sahi, N; Al-Araji, SA; Ciccarelli, O; Chard, DT; Trip, SA; (2022) Treatment-refractory warts associated with fingolimod. Practical Neurology 10.1136/pn-2022-003477. (In press). Green open access
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Sahi, N; Haider, L; Chung, K; Carrasco, FP; Kanber, B; Samson, R; Thompson, AJ; ... Chard, D; + view all (2024) Evaluating multiple sclerosis severity loci 30 years after a clinically isolated syndrome. Brain Communications , 6 (6) , Article fcae443. 10.1093/braincomms/fcae443. Green open access
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Sahi, Nitin; Ciccarelli, Olga; Houlden, Henry; Chard, Declan T; (2025) Unlocking Multiple Sclerosis Genetics. Neurology , 105 (8) , Article e214141. 10.1212/wnl.0000000000214141. (In press). Green open access
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Sahi, Nitin; Haider, Lukas; Chung, Karen; Prados Carrasco, Ferran; Kanber, Baris; Samson, Rebecca; Thompson, Alan J; ... Chard, Declan; + view all (2023) Genetic influences on disease course and severity, 30 years after a clinically isolated syndrome. Brain Communications , 5 (5) , Article fcad255. 10.1093/braincomms/fcad255. Green open access
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Savini, G; Pardini, M; Castellazzi, G; Lascialfari, A; Chard, D; D'Angelo, E; Wheeler-Kingshott, CAMG; (2019) Default Mode Network Structural Integrity and Cerebellar Connectivity Predict Information Processing Speed Deficit in Multiple Sclerosis. Frontiers in Cellular Neuroscience , 13 , Article 21. 10.3389/fncel.2019.00021. Green open access
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Sethi, V; Muhlert, N; Ron, M; Golay, X; Wheeler-Kingshott, CA; Miller, DH; Chard, DT; (2013) MS Cortical Lesions on DIR: Not Quite What They Seem? PLoS One , 8 (11) , Article e78879. 10.1371/journal.pone.0078879. Green open access
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Sethi, V; Yousry, T; Muhlert, N; Tozer, DJ; Altmann, D; Ron, M; Wheeler-Kingshott, CAM; ... Chard, DT; + view all (2015) A longitudinal study of cortical grey matter lesion subtypes in relapse-onset multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry , 87 pp. 750-753. 10.1136/jnnp-2015-311102. Green open access
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Strik, M; Chard, DT; Dekker, I; Meijer, KA; Eijlers, AJ; Pardini, M; Uitdehaag, BM; ... Schoonheim, MM; + view all (2020) Increased functional sensorimotor network efficiency relates to disability in multiple sclerosis. Multiple Sclerosis Journal 10.1177/1352458520966292. (In press). Green open access
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Sun, Jun; Xu, Siyao; Tian, Decai; Duan, Yunyun; Xu, Xiaolu; Lv, Shan; Cao, Guanmei; ... Liu, Yaou; + view all (2023) Periventricular gradients in NAWM abnormalities differ in MS, NMOSD and MOGAD. Multiple Sclerosis and Related Disorders , 75 , Article 104732. 10.1016/j.msard.2023.104732. Green open access
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Thompson, AJ; Meijer, KA; Muhlert, N; Sethi, V; Ron, MA; Miller, DH; Chard, D; ... Cercignani, M; + view all (2016) White matter tract abnormalities are associated with cognitive dysfunction and secondary progressive multiple sclerosis. Multiple Sclerosis Journal , 22 (11) pp. 1429-1437. 10.1177/1352458515622694. Green open access
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Tur, C; Grussu, F; De Angelis, F; Prados, F; Kanber, B; Calvi, A; Eshaghi, A; ... Gandini Wheeler-Kingshott, CAM; + view all (2021) Spatial patterns of brain lesions assessed through covariance estimations of lesional voxels in multiple Sclerosis: The SPACE-MS technique. NeuroImage: Clinical , 33 , Article 102904. 10.1016/j.nicl.2021.102904. Green open access
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van de Pavert, SH; Muhlert, N; Sethi, V; Wheeler-Kingshott, CA; Ridgway, GR; Geurts, JJ; Ron, M; ... Ciccarelli, O; + view all (2016) DIR-visible grey matter lesions and atrophy in multiple sclerosis: partners in crime? Journal of Neurology, Neurosurgery and Psychiatry , 87 (5) pp. 461-467. 10.1136/jnnp-2014-310142. Green open access
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Vermersch, P; Berger, T; Gold, R; Lukas, C; Rovira, A; Meesen, B; Chard, D; ... Trojano, M; + view all (2016) The clinical perspective: How to personalise treatment in MS and how may biomarkers including imaging contribute to this? MULTIPLE SCLEROSIS JOURNAL , 22 (2) pp. 18-33. 10.1177/1352458516650739. Green open access
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Wottschel, V; Alexander, DC; Kwok, PP; Chard, DT; Thompson, AJ; Miller, DH; Ciccarelli, O; (2015) Predicting outcome in clinically isolated syndrome using machine learning. NeuroImage , 7 pp. 281-287. 10.1016/j.nicl.2014.11.021. Green open access
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Wottschel, V; Chard, DT; Enzinger, C; Filippi, M; Frederiksen, JL; Gasperini, C; Giorgio, A; ... Ciccarelli, O; + view all (2019) SVM recursive feature elimination analyses of structural brain MRI predicts near-term relapses in patients with clinically isolated syndromes suggestive of Multiple Sclerosis. NeuroImage: Clinical , 24 , Article 102011. 10.1016/j.nicl.2019.102011. Green open access
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Xena-Bosch, Carla; Kodali, Srikirti; Sahi, Nitin; Chard, Declan; Llufriu, Sara; Toosy, Ahmed T; Martinez-Heras, Eloy; (2025) Advances in MRI Optic Nerve Segmentation. Multiple Sclerosis and Related Disorders , 98 , Article 106437. 10.1016/j.msard.2025.106437. Green open access
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Yaldizli, Ö; Pardini, M; Sethi, V; Muhlert, N; Liu, Z; Tozer, DJ; Samson, RS; ... Chard, DT; + view all (2016) Characteristics of lesional and extra-lesional cortical grey matter in relapsing-remitting and secondary progressive multiple sclerosis: A magnetisation transfer and diffusion tensor imaging study. Multiple Sclerosis Journal , 22 (2) pp. 150-159. 10.1177/1352458515586085. Green open access
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Yaldizli, Ö; Penner, IK; Yonekawa, T; Naegelin, Y; Kuhle, J; Pardini, M; Chard, DT; ... Sprenger, T; + view all (2016) The association between olfactory bulb volume, cognitive dysfunction, physical disability and depression in multiple sclerosis. European Journal of Neurology , 23 (3) pp. 510-519. 10.1111/ene.12891. Green open access
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Yaldizli, Ö; Sethi, V; Pardini, M; Tur, C; Mok, KY; Muhlert, N; Liu, Z; ... Chard, DT; + view all (2018) Response to the commentary of Yates RL and DeLuca GC on the study: HLA-DRB1*1501 associations with magnetic resonance imaging measures of grey matter pathology in multiple sclerosis. Multiple Sclerosis and Related Disorders , 19 pp. 168-170. 10.1016/j.msard.2016.08.006. Green open access
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Yaldizli, Ö; Sethi, V; Pardini, M; Tur, C; Mok, KY; Muhlert, N; Liu, Z; ... Chard, DT; + view all (2016) HLA-DRB∗1501 associations with magnetic resonance imaging measures of grey matter pathology in multiple sclerosis. Multiple Sclerosis and Related Disorders , 7 pp. 47-52. 10.1016/j.msard.2016.03.003. Green open access
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Yiannakas, MC; Tozer, DJ; Schmierer, K; Chard, DT; Anderson, VM; Altmann, DR; Miller, DH; (2013) ADvanced IMage Algebra (ADIMA): a novel method for depicting multiple sclerosis lesion heterogeneity, as demonstrated by quantitative MRI. Mult Scler , 19 (6) 732 - 741. 10.1177/1352458512462074. Green open access
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Zhuo, Z; Xu, X; Tian, D; Li, R; Bai, Y; Shi, Y; Xu, S; ... Liu, Y; + view all (2025) Periventricular gradient of normal-appearing white matter in normal aging and multiple neurological diseases. Journal of Advanced Research 10.1016/j.jare.2025.08.059. (In press). Green open access
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Proceedings paper

Charalambous, T; Prados Carrasco, F; Tur Gomez, C; Kanber, B; Ourselin, S; Chard, D; Clayden, JD; ... Toosy, A; + view all (2018) Longitudinal Analysis Framework of DWI Data for Reconstructing Structural Brain Networks with Application to Multiple Sclerosis. In: Kaden, E and Grussu, F and Ning, L and Tax, CMW and Veraart, J, (eds.) Computational Diffusion MRI. (pp. pp. 205-218). Springer: Cham, Switzerland.

Powell, E; Prados, F; Chard, D; Toosy, A; Clayden, JD; Wheeler-Kingshott, CGAM; (2019) Edge Weights and Network Properties in Multiple Sclerosis. In: Frangi, Alejandro and Alberola-Lopez, Carlos, (eds.) Proceedings of the 21st International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI 2018). (pp. pp. 281-291). Springer: Cham, Switzerland. Green open access
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Samson, RS; Cardoso, MJ; Muhlert, N; Sethi, V; Yaldizli, Ö; Ron, MA; Prados Carrasco, F; ... Chard, DT; + view all (2017) Longitudinal outer and inner cortical MTR abnormalities in different MS clinical phenotypes. In: Proceedings of the ISMRM 25th Annual Meeting & Exhibition. International Society for Magnetic Resonance in Medicine (ISMRM): Honululu, HI, USA. Green open access
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Wottschel, V; Alexander, DC; Chard, DT; Ciccarelli, O; Miller, DH; (2014) Prediction of time between CIS onset and clinical conversion to MS using Random Forests. In: Proceedings of the Joint Annual Meeting ISMRM-ESMRMB 2014. International Society for Magnetic Resonance in Medicine (ISMRM): Milan, Italy. Green open access
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Wottschel, V; Ciccarelli, O; Chard, DT; Miller, DH; Alexander, DC; (2013) Prediction of second neurological attack in patients with clinically isolated syndrome using support vector machines. In: PRNI 2013: 3rd International Workshop on Pattern Recognition in NeuroImaging, 22-24 June 2013, Philadelphia, PA, USA. (pp. 82 - 85). IEEE: Piscataway, US. Green open access
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Conference item

De Meo, Ermelinda; Willard, Charles; Jolly, Amy; Craveiro, Licinio; Ganzetti, Marco; Kazlauskaite, Agne; Bernasconi, Corrado; ... Cole, James; + view all (2023) Brain-age association with clinical and neuropsychological biomarkers in progressive multiple sclerosis patients. Presented at: MSMilan2023: 9th Joint ECTRIMS-ACTRIMS meeting, Milan, Italy. Green open access
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Samson, RS; Brownlee, WJ; Cardoso, MJ; Brown, WJL; Pardini, M; Prados Carrasco, F; Ourselin, S; ... Chard, DT; + view all (2016) Outer and inner cortical MTR abnormalities in clinically isolated syndromes. Presented at: ECTRIMS 2016: 32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis, London, UK. Green open access
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Samson, RS; Cardoso, MJ; Brownlee, WJ; Brown, WJL; Pardini, M; Ourselin, S; Wheeler-Kingshott, CAM; (2016) Outer and inner cortical MTR abnormalities observed in clinically isolated syndromes. Presented at: International Society for Magnetic Resonance in Medicine (ISMRM) 24th Annual Meeting & Exhibition 2016, Singapore, Malaysia. Green open access
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Poster

Ananthavarathan, Piriyankan; Sahi, Nitin; Chung, Karen; Prados, Ferran; Trip, Anand; Ciccarelli, Olga; Barkhof, Frederik; ... Chard, Declan; + view all (2023) Do early predictive factors of MS clinical outcomes have a sustained effect over time? Presented at: 9th Joint ECTRIMS-ACTRIMS Meeting, Milan, Italy. Green open access
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