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Number of items at this level: 392.

A

Ahmed, Saiam; Sydes, Matthew R; Love, Sharon B; James, Nicholas D; Carpenter, james; (2023) PS8C-01 Agreement and completeness of routine versus trial-specific patient outcome data: a systematic review. Presented at: 6th International Clinical Trials Methodology Conference, Harrogate, United Kingdom. Green open access
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Akinlua, JT; Meakin, R; Bashir, I; Freemantle, N; (2018) Beliefs about hypertension among primary health care workers and clients in Nigeria: A qualitative study. PLoS One , 13 (12) , Article e0209334. 10.1371/journal.pone.0209334. Green open access
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Akinlua, JT; Meakin, R; Fadahunsi, P; Freemantle, N; (2016) Beliefs of Health Care Providers, Lay Health Care Providers and Lay Persons in Nigeria Regarding Hypertension. A Systematic Mixed Studies Review. PLOS ONE , 11 (5) , Article e0154287. 10.1371/journal.pone.0154287. Green open access
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Akinlua, JT; Meakin, R; Freemantle, N; (2017) Beliefs about hypertension among Nigerian immigrants to the United Kingdom: A qualitative study. PLoS ONE , 12 (7) , Article e0181909. 10.1371/journal.pone.0181909. Green open access
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Akinlua, JT; Meakin, R; Umar, AM; Freemantle, N; (2015) Current Prevalence Pattern of Hypertension in Nigeria: A Systematic Review. PLoS One , 10 (10) , Article e0140021. 10.1371/journal.pone.0140021. Green open access
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Aktuerk, D; McNulty, D; Ray, D; Begaj, I; Howell, N; Freemantle, N; Pagano, D; (2016) National administrative data produces an accurate and stable risk prediction model for short-term and 1-year mortality following cardiac surgery. International Journal of Cardiology , 203 pp. 196-203. 10.1016/j.ijcard.2015.10.086. Green open access
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Al Wattar, BH; Rogozińska, E; Vale, C; Fisher, D; Petersen, I; Nicum, S; Bannington, D; ... Freemantle, N; + view all (2024) Effectiveness and safety of menopause treatments: pitfalls of available evidence and future research need. Climacteric , 27 (2) pp. 154-158. 10.1080/13697137.2023.2297880. Green open access
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Al-Lamee, R; Howard, JP; Shun-Shin, MJ; Thompson, D; Dehbi, H-M; Sen, S; Nijjer, S; ... Francis, DP; + view all (2018) Fractional Flow Reserve and Instantaneous Wave-Free Ratio as Predictors of the Placebo-Controlled Response to Percutaneous Coronary Intervention in Stable Single-Vessel Coronary Artery Disease: Physiology-Stratified Analysis of ORBITA. Circulation , 137 (23) , Article 118.033801. 10.1161/CIRCULATIONAHA.118.033801. Green open access
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Al-Lamee, R; Thompson, D; Dehbi, H-M; Sen, S; Tang, K; Davies, J; Keeble, T; ... ORBITA Investigators, .; + view all (2018) Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial. The Lancet , 391 (10115) pp. 31-40. 10.1016/S0140-6736(17)32714-9. Green open access
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Ali, A; Mckenzie, E; Hassiotis, A; Priebe, S; Lloyd-Evans, B; Jones, R; Panca, M; ... King, M; + view all (2021) A pilot randomised controlled trial of befriending by volunteers in people with intellectual disability and depressive symptoms. Journal of Intellectual Disability Research 10.1111/jir.12886.. (In press). Green open access
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Ali, A; Mckenzie, E; Rasoul, Z; Hassiotis, A; Priebe, S; Lloyd-Evans, B; Jones, R; ... King, M; + view all (2021) One-to-one volunteer befriending to reduce symptoms of depression in people with intellectual disability: a feasibility RCT. Public Health Research , 9 (10) pp. 1-80. 10.3310/phr09100. Green open access
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Ali, A; Mckenzie, E; Hassiotis, A; Priebe, S; Lloyd-Evans, B; Omar, R; Jones, R; ... King, M; + view all (2020) One-to-one befriending for people with intellectual disability and symptoms of depression: protocol for a pilot randomised controlled trial. BMJ Open , 10 (6) , Article e033989. 10.1136/bmjopen-2019-033989. Green open access
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Almeida Silva Salvado, DS; (2017) SPECT System Design Optimisation for a Simultaneous SPECT/MRI Clinical Scanner. Doctoral thesis , UCL (University College London). Green open access
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AlSowaiegh, R; O’Brien, A; Freemantle, N; (2023) A critique on "A randomized evaluation of on-site monitoring nested in a multinational randomized trial". Clinical Trials 10.1177/17407745231204803. (In press). Green open access
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Arai, L; Panca, M; Morris, S; Curtis-Tyler, K; Lucas, PJ; Roberts, HM; (2015) Time, monetary and other costs of participation in family-based child weight management interventions: qualitative and systematic review evidence. PLoS One , 10 (4) , Article e0123782. 10.1371/journal.pone.0123782. Green open access
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Arden, NK; Cro, S; Sheard, S; Doré, CJ; Bara, A; Tebbs, SA; Hunter, DJ; ... Keen, R; + view all (2016) The effect of vitamin D supplementation on knee osteoarthritis, the VIDEO study: a randomised controlled trial. Osteoarthritis and Cartilage , 24 (11) pp. 1858-1866. 10.1016/j.joca.2016.05.020. Green open access
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Avery, KNL; Williamson, PR; Gamble, C; Francischetto, EOC; Metcalfe, C; Davidson, P; Williams, H; ... Treweek, S; + view all (2017) Informing efficient randomised controlled trials: Exploration of challenges in developing progression criteria for internal pilot studies. BMJ Open , 7 (2) , Article e013537. 10.1136/bmjopen-2016-013537. Green open access
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B

Bailey, JV; Murray, E; (2016) The Men’s Safer Sex Trial: A feasibility randomised controlled trial of an interactive digital intervention to increase condom use in men. Digital Health , 2 pp. 1-12. 10.1177/2055207616679002. Green open access
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Bailey, JV; Webster, R; Hunter, R; Freemantle, N; Rait, G; Michie, S; Estcourt, C; ... Murray, E; + view all (2015) The Men's Safer Sex (MenSS) trial: protocol for a pilot randomised controlled trial of an interactive digital intervention to increase condom use in men. BMJ Open , 5 (2) , Article e007552. 10.1136/bmjopen-2014-007552. Green open access
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Bailey, JV; Webster, R; Hunter, R; Griffin, M; Freemantle, N; Rait, G; Estcourt, C; ... Murray, E; + view all (2016) The Men's Safer Sex project: intervention development and feasibility randomised controlled trial of an interactive digital intervention to increase condom use in men. Health Technol Assess , 20 (91) pp. 1-124. 10.3310/hta20910. Green open access
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Balint, B; Killaspy, H; Marston, L; Barnes, T; Latorre, A; Joyce, E; Clarke, CS; ... Martino, D; + view all (2018) Development and clinimetric assessment of a nurse-administered screening tool for movement disorders in psychosis. BJPsych Open , 4 (5) pp. 404-410. 10.1192/bjo.2018.55. Green open access
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Barili, Fabio; Freemantle, Nicholas; Musumeci, Francesco; Martin, Barbara; Anselmi, Amedeo; Rinaldi, Mauro; Kaul, Sanjay; ... Parolari, Alessandro; + view all (2022) Five-year outcomes in trials comparing transcatheter aortic valve implantation versus surgical aortic valve replacement: a pooled meta-analysis of reconstructed time-to-event data. European Journal of Cardio-Thoracic Surgery , 61 (5) pp. 977-987. 10.1093/ejcts/ezab516. Green open access
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Barili, F; Freemantle, N; Casado, AP; Rinaldi, M; Folliguet, T; Musumeci, F; Gerosa, G; (2020) Mortality in trials on transcatheter aortic valve implantation versus surgical aortic valve replacement: a pooled meta-analysis of Kaplan-Meier-derived individual patient data. European Journal of Cardio-Thoracic Surgery , 58 (2) pp. 221-229. 10.1093/ejcts/ezaa087. Green open access
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Barili, F; Freemantle, N; Folliguet, T; Muneretto, C; De Bonis, M; Czerny, M; Obadia, JF; ... Menicanti, L; + view all (2017) The flaws in the detail of an observational study on transcatheter aortic valve implantation versus surgical aortic valve replacement in intermediate-risks patients. European Journal of Cardio-Thoracic Surgery , 51 (6) pp. 1031-1035. 10.1093/ejcts/ezx058. Green open access
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Barili, F; Freemantle, N; Parolari, A; (2020) Five-Year Outcomes with Transcatheter Aortic-Valve Replacement. The New England Journal of Medicine , 383 (6) pp. 594-596. 10.1056/NEJMc2018853. Green open access
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Barili, F; Parolari, A; Kappetein, PA; Freemantle, N; (2018) Statistical Primer: heterogeneity, random- or fixed-effects model analyses? Interactive CardioVascular and Thoracic Surgery , 27 (3) pp. 317-321. 10.1093/icvts/ivy163. Green open access
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Bastian, Mike; Freemantle, Nick; Rossi, Ana B; Shumel, Brad; Le Bagousse, Gaelle Bego; Wang, Zhixiao; Xu, Yingxin; (2024) Letter to the Editor Regarding ‘Matching-Adjusted Indirect Comparison of the Long-Term Efficacy Maintenance and Adverse Event Rates of Lebrikizumab Versus Dupilumab in Moderate-to-Severe Atopic Dermatitis’. Dermatology and Therapy , 14 (3) pp. 819-821. 10.1007/s13555-024-01106-2. Green open access
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Bekker, LG; Delany-Moretlwe, S; Biccard, B; duToit, L; Lovat, LB; Dehbi, HM; Moonesinghe, R; ... Avidan, MS; + view all (2020) Protecting healthcare workers: A critical part of the COVID-19 response. South African Medical Journal , 110 (12) pp. 1154-1155. 10.7196/SAMJ.2020.v110i12.15048. Green open access
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Bennett, Sophie D; Cross, J Helen; Chowdhury, Kashfia; Ford, Tamsin; Heyman, Isobel; Coughtrey, Anna E; Dalrymple, Emma; ... Shafran, Roz; + view all (2024) Clinical effectiveness of the psychological therapy Mental Health Intervention for Children with Epilepsy in addition to usual care compared with assessment-enhanced usual care alone: a multicentre, randomised controlled clinical trial in the UK. The Lancet 10.1016/S0140-6736(23)02791-5. (In press). Green open access
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Bennett, A; Chow, CK; Chou, M; Dehbi, H-M; Webster, R; Salam, A; Patel, A; ... Rodgers, A; + view all (2017) Efficacy and Safety of Quarter-Dose Blood Pressure–Lowering AgentsNovelty and Significance. Hypertension , 70 (1) pp. 85-93. 10.1161/HYPERTENSIONAHA.117.09202. Green open access
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Bennett, S; (2021) M.I.C.E – Mental Health Intervention for Children with Epilepsy: A randomised controlled, multi-centre clinical trial evaluating the clinical and cost-effectiveness of MATCH-ADTC in addition to usual care compared to usual care alone for children and young people with common mental health disorders and epilepsy – Study protocol. Trials , 22 , Article 132. 10.1186/s13063-020-05003-9. Green open access
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Bennett, S; Heyman, I; Coughtrey, A; Buszewicz, M; Byford, S; Dore, C; Fonagy, P; ... Shafran, R; + view all (2019) Assessing feasibility of routine identification tools for mental health disorder in neurology clinics. Archives of Disease in Childhood , 104 (12) pp. 1161-1166. 10.1136/archdischild-2018-316595. Green open access
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Best, Jonathan G; Arram, Liz; Ahmed, Norin; Balogun, Maryam; Bennett, Kate; Bordea, Ekaterina; Campos, Marta G; ... OPTIMAS investigators, .; + view all (2022) Optimal timing of anticoagulation after acute ischemic stroke with atrial fibrillation (OPTIMAS): Protocol for a randomized controlled trial. International Journal of Stroke , 17 (5) pp. 583-589. 10.1177/17474930211057722. Green open access
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Beyersdorf, F; Bauer, T; Freemantle, N; Walther, T; Frerker, C; Herrmann, E; Bleiziffer, S; ... Hamm, CW; + view all (2021) Five-year outcome in 18 010 patients from the German Aortic Valve Registry. European Journal of Cardio-Thoracic Surgery , 60 (5) pp. 1139-1146. 10.1093/ejcts/ezab216. Green open access
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Bhat, A; Irizar, H; Thygesen, JH; Kuchenbaecker, K; Pain, O; Adams, RA; Zartaloudi, E; ... Bramon, E; + view all (2021) Transcriptome-wide association study reveals two genes that influence mismatch negativity. Cell Reports , 34 (11) , Article 108868. 10.1016/j.celrep.2021.108868. Green open access
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Blackstone, James; Williams, Thomas; Nicholas, Jennifer M; Bordea, Ekaterina; De Angelis, Floriana; Bianchi, Alessia; Calvi, Alberto; ... Chataway, Jeremy; + view all (2024) Evaluating the effectiveness of simvastatin in slowing the progression of disability in secondary progressive multiple sclerosis (MS-STAT2): protocol for a multicentre, randomised controlled, double-blind, phase 3 clinical trial in the UK. BMJ Open , 14 (9) , Article e086414. 10.1136/bmjopen-2024-086414. Green open access
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Blakey, R; Ranlund, S; Zartaloudi, E; Cahn, W; Calafato, S; Colizzi, M; Crespo-Facorro, B; ... Bramon, E; + view all (2018) Associations between psychosis endophenotypes across brain functional, structural, and cognitive domains. Psychological Medicine , 48 (8) pp. 1325-1340. 10.1017/S0033291717002860. Green open access
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Blencowe, NS; Brown, JM; Cook, JA; Metcalfe, C; Morton, DG; Nicholl, J; Sharples, LD; ... Members of the MRC Hub for Trials Methodology Research Network W; + view all (2015) Interventions in randomised controlled trials in surgery: issues to consider during trial design. Trials , 16 , Article 392. 10.1186/s13063-015-0918-4. Green open access
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Blonde, L; Bailey, T; Sullivan, SD; Freemantle, N; (2021) Insulin glargine 300 units/mL for the treatment of individuals with type 2 diabetes in the real world: A review of the DELIVER programme. Diabetes, Obesity and Metabolism 10.1111/dom.14405. (In press). Green open access
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Bonadonna, RC; Mauricio, D; Mueller-Wieland, D; Freemantle, N; Bigot, G; Mauquoi, C; Ciocca, A; ... Gourdy, P; + view all (2021) Impact of Age on the Effectiveness and Safety of Insulin Glargine 300 U/mL: Results from the REALI European Pooled Data Analysis. Diabetes Therapy , 12 pp. 1073-1097. 10.1007/s13300-021-01030-0. Green open access
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Bordea, Ekaterina; (2020) TARVA Health Economics Analysis Plan. University College London (UCL): London, UK. Green open access
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Bortolussi, G; McNulty, D; Waheed, H; Mawhinney, JA; Freemantle, N; Pagano, D; (2019) Identifying cardiac surgery operations in hospital episode statistics administrative database, with an OPCS-based classification of procedures, validated against clinical data. BMJ Open , 9 (3) , Article e023316. 10.1136/bmjopen-2018-023316. Green open access
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Bosch, M; McKenzie, JE; Mortimer, D; Tavender, EJ; Francis, JJ; Brennan, SE; Knott, JC; ... NET Program; + view all (2014) Implementing evidence-based recommended practices for the management of patients with mild traumatic brain injuries in Australian emergency care departments: study protocol for a cluster randomised controlled trial. Trials , 15 , Article 281. 10.1186/1745-6215-15-281. Green open access
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Bosch, M; McKenzie, JE; Ponsford, JL; Turner, S; Chau, M; Tavender, EJ; Knott, JC; ... Green, SE; + view all (2019) Evaluation of a targeted, theory-informed implementation intervention designed to increase uptake of emergency management recommendations regarding adult patients with mild traumatic brain injury: results of the NET cluster randomised trial. Implementation Science , 14 (1) , Article 4. 10.1186/s13012-018-0841-7. Green open access
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Boshier, FAT; Venturini, C; Stirrup, O; Guerra-Assunção, JA; Alcolea-Medina, A; Becket, AH; Byott, M; ... COG-UK HOCI Variant Substudy consortium*, The COVID-19 Genomics; + view all (2021) The Alpha variant was not associated with excess nosocomial SARS-CoV-2 infection in a multi-centre UK hospital study. Journal of Infection , 83 (6) pp. 693-700. 10.1016/j.jinf.2021.09.022. Green open access
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Brauer, R; Wei, L; Ma, T; Athauda, D; Girges, C; Vijiaratnam, N; Auld, G; ... Foltynie, T; + view all (2020) Diabetes medications and risk of Parkinson's disease: a cohort study of patients with diabetes. Brain , 143 (10) pp. 3067-3076. 10.1093/brain/awaa262. Green open access
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Brown, L-AK; Freemantle, N; Breuer, J; Dehbi, H-M; Chowdhury, K; Jones, G; Ikeji, F; ... Lowe, DM; + view all (2021) Early antiviral treatment in outpatients with COVID-19 (FLARE): a structured summary of a study protocol for a randomised controlled trial. Trials , 22 (1) , Article 193. 10.1186/s13063-021-05139-2. Green open access
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Bunce, C; Czanner, G; Grzeda, MT; Doré, CJ; Freemantle, N; (2017) Ophthalmic statistics note 12: multivariable or multivariate: what's in a name? British Journal of Ophthalmology , 101 (10) pp. 1303-1305. 10.1136/bjophthalmol-2017-310846. Green open access
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Bunce, C; Czanner, G; Moschandreas, J; Stratton, IM; Doré, C; Freemantle, N; Ophthalmic Statistics Group, .; (2020) Ophthalmic statistics note 14: method agreement studies in ophthalmology: the intraclass correlation coefficient? British Journal of Dermatology 10.1136/bjophthalmol-2019-314947. (In press). Green open access
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Bunce, C; Patel, KV; Xing, W; Freemantle, N; Doré, CJ; (2014) Ophthalmic statistics note 2: Absence of evidence is not evidence of absence. British Journal of Ophthalmology , 98 (5) 703 - 705. 10.1136/bjophthalmol-2013-304811. Green open access
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Bunce, C; Patel, KV; Xing, W; Freemantle, N; Doré, CJ; (2014) Ophthalmic statistics note 1: Unit of analysis. British Journal of Ophthalmology , 98 (3) 408 - 412. 10.1136/bjophthalmol-2013-304587. Green open access
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Bunce, C; Quartilho, A; Freemantle, N; Doré, CJ; Ophthalmic Statistics Group; (2016) Ophthalmic statistics note 8: missing data - exploring the unknown. [Editorial comment]. British Journal of Ophthalmology , 100 (3) pp. 291-294. 10.1136/bjophthalmol-2015-307821. Green open access
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Bunce, C; Stephenson, J; Doré, CJ; Freemantle, N; Ophthalmic Statistics Group, .; (2016) Ophthalmic statistics note 10: data transformations. British Journal of Ophthalmology , 100 (12) pp. 1591-1593. 10.1136/bjophthalmol-2016-308824. Green open access
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Bunce, C; Stratton, IM; Elders, A; Czanner, G; Doré, C; Freemantle, N; Ophthalmic Statistics Group; (2019) Ophthalmic statistics note 13: method agreement studies in ophthalmology-please don't carry on correlating…. British Journal of Ophthalmology , 103 (9) pp. 1201-1203. 10.1136/bjophthalmol-2018-313759. Green open access
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Buxton, H; Gomes, M; Gafoor, R; Taylor, Z; Totsika, V; (2024) Measuring quality of life of adults with intellectual disabilities: Psychometric evaluation of the personal outcomes scale in the United Kingdom. Journal of Applied Research in Intellectual Disabilities , 37 (2) , Article e13189. 10.1111/jar.13189. Green open access
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C

Calafato, MS; Austin-Zimmerman, I; Thygesen, JH; Sairam, M; Metastasio, A; Marston, L; Abad-Santos, F; ... Bramon, E; + view all (2020) The effect of CYP2D6 variation on antipsychotic-induced hyperprolactinaemia: a systematic review and meta-analysis. The Pharmacogenomics Journal 10.1038/s41397-019-0142-9. (In press). Green open access
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Calafato, MS; Thygesen, JH; Ranlund, S; Zartaloudi, E; Cahn, W; Crespo-Facorro, B; Díez-Revuelta, Á; ... Bramon, E; + view all (2018) Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders. The British Journal of Psychiatry , 213 (3) pp. 535-541. 10.1192/bjp.2018.89. Green open access
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Calvert, M; Duffy, H; Freemantle, N; Davis, R; Lip, GY; Gill, P; (2012) Population health status of South Asian and African-Caribbean communities in the United Kingdom. BMC Health Services Research , 12 , Article 101. 10.1186/1472-6963-12-101. Green open access
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Chau, M; Richards, T; Evans, C; Butcher, A; Collier, T; Klein, A; (2017) The UK Cardiac and Vascular Surgery Interventional Anaemia Response (CAVIAR) Study: protocol for an observational cohort study to determine the impact and effect of preoperative anaemia management in cardiac and vascular surgical patients. BMJ Open , 7 (4) , Article e014872. 10.1136/bmjopen-2016-014872. Green open access
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Cheng, AYY; Wong, J; Freemantle, N; Acharya, SH; Ekinci, E; (2020) The Safety and Efficacy of Second-Generation Basal Insulin Analogues in Adults with Type 2 Diabetes at Risk of Hypoglycemia and Use in Other Special Populations: A Narrative Review. Diabetes Therapy , 11 pp. 2555-2593. 10.1007/s13300-020-00925-8. Green open access
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China, L; Freemantle, N; Forrest, E; Kallis, Y; Ryder, SD; Wright, G; O'Brien, A; (2021) Targeted Albumin Therapy Does Not Improve Short-Term Outcome in Hyponatremic Patients Hospitalized With Complications of Cirrhosis: Data From the ATTIRE Trial. The American Journal of Gastroenterology , 116 pp. 2292-2295. 10.14309/ajg.0000000000001488. Green open access
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China, L; Freemantle, N; Forrest, E; Kallis, Y; Ryder, SD; Wright, G; Portal, AJ; ... O'Brien, A; + view all (2021) A Randomized Trial of Albumin Infusions in Hospitalized Patients with Cirrhosis. The New England Journal of Medicine , 384 (9) pp. 808-817. 10.1056/NEJMoa2022166. Green open access
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China, L; Freemantle, N; O'Brien, A; (2021) Randomized Trials of Interventions for Hospitalized Patients with Cirrhosis. Reply. The New England Journal of Medicine , 384 (23) , Article e90. 10.1056/NEJMc2105498. Green open access
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China, L; Tittanegro, T; Crocombe, D; Forrest, E; Kallis, Y; Ryder, SD; Wright, G; ... O'Brien, A; + view all (2023) Investigating potential confounding by indication when considering the association between proton pump inhibitor use, infection, hepatic encephalopathy and mortality in hospitalised decompensated cirrhosis: a post-hoc analysis of the ATTIRE trial. eClinicalMedicine , 58 , Article 101924. 10.1016/j.eclinm.2023.101924. Green open access
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Chiuzan, C; Dehbi, HM; (2024) The 3 + 3 design in dose-finding studies with small sample sizes: Pitfalls and possible remedies. Clinical Trials 10.1177/17407745241240401. (In press). Green open access
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Cho, G; Anie, KA; Buckton, J; Kiilu, P; Layton, M; Alexander, L; Hemmaway, C; ... Meredith, S; + view all (2016) SWIM (sickle with ibuprofen and morphine) randomised controlled trial fails to recruit: lessons learnt. BMJ OPEN , 6 (6) 10.1136/bmjopen-2016-011276. Green open access
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Chow, CK; Thakkar, J; Bennett, A; Hillis, G; Burke, M; Usherwood, T; Vo, K; ... Rodgers, A; + view all (2017) Quarter-dose quadruple combination therapy for initial treatment of hypertension: placebo-controlled, crossover, randomised trial and systematic review. The Lancet , 389 (10073) pp. 1035-1042. 10.1016/S0140-6736(17)30260-X. Green open access
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Chowdhury, K; Dore, C; Burr, JM; Bunce, C; Raynor, M; Edwards, M; Larkin, DFP; (2019) A randomised, controlled, observer-masked trial of corneal cross-linking for progressive keratoconus in children: the KERALINK protocol. BMJ Open , 9 (9) , Article e028761. 10.1136/bmjopen-2018-028761. Green open access
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Chowdhury, K; Doré, CJ; Bunce, C; Larkin, DFP; (2020) Corneal cross-linking versus standard care in children with keratoconus - a randomised, multicentre, observer-masked trial of efficacy and safety (KERALINK): a statistical analysis plan. Trials , 21 , Article 523. 10.1186/s13063-020-04392-1. Green open access
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Choy, E; Freemantle, N; Proudfoot, C; Chen, C-I; Pollissard, L; Kuznik, A; van Hoogstraten, H; ... Thi-Minh-Thao, H; + view all (2019) Indirect Treatment Comparison of the Efficacy and Safety of Sarilumab Monotherapy in Rheumatoid Arthritis Patients with Inadequate Response to Conventional Disease-Modifying Antirheumatic Drugs. Advances in Therapy , 36 (4) pp. 817-827. 10.1007/s12325-019-00912-x. Green open access
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Choy, E; Freemantle, N; Proudfoot, C; Chen, CI; Pollissard, L; Kuznik, A; Van Hoogstraten, H; ... Huynh, TMT; + view all (2019) Evaluation of the efficacy and safety of sarilumab combination therapy in patients with rheumatoid arthritis with inadequate response to conventional disease-modifying antirheumatic drugs or tumour necrosis factor α inhibitors: Systematic literature review and network meta-analyses. RMD Open , 5 , Article e000798. 10.1136/rmdopen-2018-000798. Green open access
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Christie, D; Hudson, LD; Kinra, S; Wong, ICK; Nazareth, I; Cole, TJ; Sovio, U; ... Viner, RM; + view all (2017) A community-based motivational personalised lifestyle intervention to reduce BMI in obese adolescents: results from the Healthy Eating and Lifestyle Programme (HELP) randomised controlled trial. Archives of Disease in Childhood , 102 (8) pp. 695-701. 10.1136/archdischild-2016-311586. Green open access
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Ciurtin, C; Leandro, M; Fitz-Clarence, H; Nguyen, H; Walsh, SB; Isenberg, DA; (2015) Clinical trials perception in rheumatology patients: experience from a single rheumatology tertiary center. The Journal of Rheumatology , 42 (6) pp. 988-993. 10.3899/jrheum.141091. Green open access
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Clarke, CS; Duffy, L; Lewis, G; Freemantle, N; Gilbody, S; Kendrick, T; Kessler, D; ... Hunter, RM; + view all (2021) Cost-Utility Analysis of Discontinuing Antidepressants in England Primary Care Patients Compared with Long-Term Maintenance: The ANTLER Study. APPLIED HEALTH ECONOMICS AND HEALTH POLICY 10.1007/s40258-021-00693-x. Green open access
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Cleland, John GF; Bristow, Michael R; Freemantle, Nicholas; Olshansky, Brian; Gras, Daniel; Saxon, Leslie; Tavazzi, Luigi; ... de Mets, David; + view all (2022) The effect of cardiac resynchronization without a defibrillator on morbidity and mortality: an individual patient data meta-analysis of COMPANION and CARE-HF. European Journal of Heart Failure 10.1002/ejhf.2524. (In press). Green open access
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Cleland, John GF; McMurray, John JV; Freemantle, Nick; (2024) Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction. The New England Journal of Medicine , 391 (1) pp. 94-95. 10.1056/NEJMc2406095. Green open access
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Cohen, H; Doré, CJ; Clawson, S; Hunt, BJ; Isenberg, D; Khamashta, M; Muirhead, N; (2015) Rivaroxaban in antiphospholipid syndrome (RAPS) protocol: a prospective, randomized controlled phase II/III clinical trial of rivaroxaban versus warfarin in patients with thrombotic antiphospholipid syndrome, with or without SLE. Lupus , 24 (10) pp. 1087-1094. 10.1177/0961203315581207. Green open access
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Cohen, H; Hunt, B; Efythymiou, M; Arachchillage, D; Ruiz, M; Clawson, S; Muirhead, N; ... Collaborators, RAPST; + view all (2015) Raps (rivaroxaban in antiphospholipid syndrome): a prospective randomised controlled phase II/III clinical trial of rivaroxaban vs. warfarin in patients with thrombotic antiphospholipid syndrome, with or without SLE. Journal of Thrombosis and Haemostasis , 13 , Article LB003. DOI: 10.1111/jth.12993. Green open access
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Cohen, H; Hunt, BJ; Efthymiou, M; Arachchillage, DR; Mackie, IJ; Clawson, S; Sylvestre, Y; ... RAPS trial investigators, .; + view all (2016) Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised, controlled, open-label, phase 2/3, non-inferiority trial. Lancet Haematology , 3 (9) e426-e436. 10.1016/S2352-3026(16)30079-5. Green open access
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Connor, C; Birchwood, M; Freemantle, N; Palmer, C; Channa, S; Barker, C; Patterson, P; (2016) Don't turn your back on the symptoms of psychosis: the results of a proof-of-principle, quasi-experimental intervention to reduce duration of untreated psychosis. BMC Psychiatry , 16 , Article 127. 10.1186/s12888-016-0816-7. Green open access
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Connor, C; Birchwood, M; Palmer, C; Channa, S; Freemantle, N; Lester, H; Patterson, P; (2013) Don't turn your back on the symptoms of psychosis: a proof-of-principle, quasi-experimental public health trial to reduce the duration of untreated psychosis in Birmingham, UK. BMC Psychiatry , 13 , Article 67. 10.1186/1471-244X-13-67. Green open access
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Contoli, Marco; Porsbjerg, Celeste; Buchs, Sarah; Larsen, Julie Rask; Freemantle, Nick; Fritzsching, Benedikt; (2023) Real-world, long-term effectiveness of allergy immunotherapy in allergic rhinitis: Subgroup analyses of the REACT study. The Journal of Allergy and Clinical Immunology , 152 (2) 445-452.E4. 10.1016/j.jaci.2023.02.024. Green open access
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Contoli, Marco; Porsbjerg, Celeste; Fritzsching, Benedikt; Buchs, Sarah; Rask Larsen, Julie; Freemantle, Nick; (2023) Long-term, real-world effects of allergy immunotherapy in children with allergic rhinitis and pre-existing asthma - a subgroup analysis of the REACT study. Allergologie , 46 (10) Green open access
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Cook, A; Embleton, A; Jayson, G; Kaplan, R; Kristensen, G; Parmar, MK; Pfisterer, J; ... Perren, T; + view all (2017) ICON7: Ovarian cancer, platinum second-line chemotherapy and overall survival. Presented at: 42nd ESMO Congress (ESMO 2017), Madrid, Spain. Green open access
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Cook, JA; Bunce, C; Doré, CJ; Freemantle, N; Ophthalmic Statistics Group, .; (2015) Ophthalmic statistics note 6: effect sizes matter. Br J Ophthalmol , 99 (5) 580 - 581. 10.1136/bjophthalmol-2014-306303. Green open access
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Cooper, C; Harvey, NC; Bishop, NJ; Kennedy, S; Papageorghiou, AT; Schoenmakers, I; Fraser, R; ... Javaid, MK; + view all (2016) Maternal gestational vitamin D supplementation and off spring bone health (MAVIDOS): a multicentre, double-blind, randomised placebo-controlled trial. The Lancet Diabetes & Endocrinology , 4 (5) pp. 393-402. 10.1016/S2213-8587(16)00044-9. Green open access
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Cosgrove, DO; Dore, C; Tourasse, C; Ohlinger, R; Madjar, H; Hooley, R; Balu-Maestro, C; ... Larsen, L; + view all (2010) Preliminary assessment of ShearWave (TM) elastography features in predicting breast lesion malignancy. In: Royal College of Radiologists Breast Group Annual Scientific Meeting 2010. (pp. S5). BioMed Central Green open access
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Crocombe, Dominic; Ahmed, Norin; Balakrishnan, Indran; Bordea, Ekaterina; Chau, Marisa; China, Louise; Corless, Lynsey; ... O'Brien, Alastair; + view all (2022) ASEPTIC: primary antibiotic prophylaxis using co-trimoxazole to prevent SpontanEous bacterial PeritoniTIs in Cirrhosis-study protocol for an interventional randomised controlled trial. Trials , 23 (1) , Article 812. 10.1186/s13063-022-06727-6. Green open access
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Crocombe, Dominic; Freemantle, Nick; O'Brien, Alastair; (2022) Additional Analyses for the Published Primary Norfloxacin Prophylaxis for APASL-Defined Acute-on-Chronic Liver Failure. American Journal of Gastroenterology , 117 (5) pp. 814-815. 10.14309/ajg.0000000000001702. Green open access
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Crossan, C; Dehbi, HM; Williams, H; Poulter, N; Rodgers, A; Jan, S; Thom, S; (2018) A protocol for an economic evaluation of a polypill in patients with established or at high risk of cardiovascular disease in a UK NHS setting: RUPEE (NHS) study. BMJ Open , 8 (3) , Article e013063. 10.1136/bmjopen-2016-013063. Green open access
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Cumberland, PM; Czanner, G; García-Fiñana, M; Bunce, C; Doré, CJ; Freemantle, N; (2014) Ophthalmic statistics note: The perils of dichotomising continuous variables. British Journal of Ophthalmology , 98 (6) 841 - 843. 10.1136/bjophthalmol-2014-304930. Green open access
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Davies, JE; Sen, S; Dehbi, H-M; Al-Lamee, R; Petraco, R; Nijjer, SS; Bhindi, R; ... Escaned, J; + view all (2017) Use of the Instantaneous Wave-free Ratio or Fractional Flow Reserve in PCI. New England Journal of Medicine , 376 (19) pp. 1824-1834. 10.1056/NEJMoa1700445. Green open access
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Day, AC; Burr, JM; Bennett, K; Bunce, C; Doré, CJ; Rubin, GS; Nanavaty, MA; ... FACT group, .; + view all (2020) Femtosecond Laser-Assisted Cataract Surgery Versus Phacoemulsification Cataract Surgery (FACT): A Randomized Noninferiority Trial. Ophthalmology 10.1016/j.ophtha.2020.02.028. (In press). Green open access
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Day, AC; Burr, JM; Bennett, K; Doré, CJ; Bunce, C; Hunter, R; Nanavaty, MA; ... FACT trial group¢; + view all (2020) Femtosecond laser-assisted cataract surgery compared with phacoemulsification cataract surgery (FACT): a randomised non-inferiority trial, 1 year outcomes. Journal of Cataract and Refractive Surgery 10.1097/j.jcrs.0000000000000257. (In press). Green open access
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Day, AC; Burr, JM; Bennett, K; Hunter, R; Bunce, C; Doré, CJ; Nanavaty, MA; ... Wilkins, MR; + view all (2021) Femtosecond laser-assisted cataract surgery compared with phacoemulsification: the FACT non-inferiority RCT. Health Technology Assessment , 25 (6) pp. 1-68. 10.3310/hta25060. Green open access
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Day, AC; Burr, JM; Bunce, C; Doré, CJ; Sylvestre, Y; Wormald, RP; Round, J; ... Wilkins, MR; + view all (2015) Randomised, single-masked non-inferiority trial of femtosecond laser-assisted versus manual phacoemulsification cataract surgery for adults with visually significant cataract: the FACT trial protocol. BMJ Open , 5 (11) , Article e010381. 10.1136/bmjopen-2015-010381. Green open access
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Day, E; Copello, A; Seddon, JL; Christie, M; Bamber, D; Powell, C; Bennett, C; ... Freemantle, N; + view all (2018) A pilot feasibility randomised controlled trial of an adjunct brief social network intervention in opiate substitution treatment services. BMC Psychiatry , 18 , Article 8. 10.1186/s12888-018-1600-7. Green open access
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Day, E; Copello, A; Seddon, JL; Christie, M; Bamber, D; Powell, C; George, S; ... Freemantle, N; + view all (2013) Pilot study of a social network intervention for heroin users in opiate substitution treatment: study protocol for a randomized controlled trial. Trials , 14 , Article 264. 10.1186/1745-6215-14-264. Green open access
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Dayan, Victor; Grant, Stuart W; Brophy, James M; Barili, Fabio; Freemantle, Nick; (2024) Composite end points and competing risks analysis. Interdisciplinary CardioVascular and Thoracic Surgery , 39 (1) , Article ivae126. 10.1093/icvts/ivae126. Green open access
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Dehbi, Hakim‐Moulay; Embleton‐Thirsk, Andrew; McCaw, Zachary Ryan; (2022) Sample size calculation for randomized selection trials with a time‐to‐event endpoint and a margin of practical equivalence. Statistics in Medicine 10.1002/sim.9490. (In press). Green open access
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Dehbi, HM; O'Quigley, J; Iasonos, A; (2021) Controlled backfill in oncology dose-finding trials. Contemporary Clinical Trials , 111 , Article 106605. 10.1016/j.cct.2021.106605. Green open access
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Dehbi, H-M; Hackshaw, A; (2020) Sample size calculation in randomised phase II selection trials using a margin of practical equivalence. Trials , 21 , Article 301. 10.1186/s13063-020-04248-8. Green open access
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Dehbi, H-M; Lowe, DM; O'Quigley, J; (2020) Early phase dose-finding trials in virology. Statistics in Medicine 10.1002/sim.8771. (In press). Green open access
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Dehbi, H-M; Mallick, U; Wadsley, J; Newbold, K; Harmer, C; Hackshaw, A; (2019) Recurrence after low-dose radioiodine ablation and recombinant human thyroid-stimulating hormone for differentiated thyroid cancer (HiLo): long-term results of an open-label, non-inferiority randomised controlled trial. Lancet Diabetes and Endocrinology , 7 (1) pp. 44-51. 10.1016/S2213-8587(18)30306-1. Green open access
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Dehbi, H-M; Royston, P; Hackshaw, A; (2017) Life expectancy difference and life expectancy ratio: two measures of treatment effects in randomised trials with non-proportional hazards. BMJ (357) , Article j2250. 10.1136/bmj.j2250. Green open access
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Dehbi, HM; Blangiardo, M; Gulliver, J; Fecht, D; de Hoogh, K; Al-Kanaani, Z; Tillin, T; ... Hansell, AL; + view all (2016) Air pollution and cardiovascular mortality with over 25 years follow-up: A combined analysis of two British cohorts. Environment International 10.1016/j.envint.2016.12.004. Green open access
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Downs, M; Blighe, A; Carpenter, R; Feast, A; Froggatt, K; Gordon, S; Hunter, R; + view all (2021) A complex intervention to reduce avoidable hospital admissions in nursing homes: a research programme including the BHiRCH-NH pilot cluster RCT. (Programme Grants for Applied Research 9:2 , pp. pp. 1-200 ). National Institute for Health Research: Perth, Scotland. Green open access
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Dowswell, G; Ryan, A; Taylor, A; Daley, A; Freemantle, N; Brookes, M; Jones, J; ... Sue, W; + view all (2012) Designing an intervention to help people with colorectal adenomas reduce their intake of red and processed meat and increase their levels of physical activity: a qualitative study. BMC Cancer , 12 , Article 255. 10.1186/1471-2407-12-255. Green open access
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Drake, RJ; Husain, N; Marshall, M; Lewis, SW; Tomenson, B; Chaudhry, IB; Everard, L; ... Birchwood, M; + view all (2020) Effect of delaying treatment of first-episode psychosis on symptoms and social outcomes: a longitudinal analysis and modelling study. The Lancet Psychiatry , 7 (7) pp. 602-610. 10.1016/S2215-0366(20)30147-4. Green open access
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Duffy, L; Clarke, CS; Lewis, G; Marston, L; Freemantle, N; Gilbody, S; Hunter, R; ... Lewis, G; + view all (2021) Antidepressant medication to prevent depression relapse in primary care: the ANTLER RCT. Health Technology Assessment , 25 (69) 10.3310/hta25690. Green open access
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Duffy, L; Bacon, F; Clarke, CS; Donkor, Y; Freemantle, N; Gilbody, S; Hunter, R; ... Lewis, G; + view all (2019) A randomised controlled trial assessing the use of citalopram, sertraline, fluoxetine and mirtazapine in preventing relapse in primary care patients who are taking long-term maintenance antidepressants (ANTLER: ANTidepressants to prevent reLapse in dEpRession): study protocol for a randomised controlled trial. Trials , 20 (1) , Article 319. 10.1186/s13063-019-3390-8. Green open access
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Dulai, Rajdip; Sulke, Neil; Freemantle, Nick; Lambiase, Pier D; Farwell, David; Srinivasan, Neil T; Tan, Stuart; ... Veasey, Rick A; + view all (2024) Pulmonary Vein Isolation vs Sham Intervention in Symptomatic Atrial Fibrillation: The SHAM-PVI Randomized Clinical Trial. JAMA: Journal of the American Medical Association 10.1001/jama.2024.17921. (In press). Green open access
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Eastwood, SV; Tillin, T; Dehbi, H-M; Wright, A; Forouhi, NG; Godsland, I; Whincup, P; ... Chaturvedi, N; + view all (2015) Ethnic Differences in Associations Between Fat Deposition and Incident Diabetes and Underlying Mechanisms: The SABRE Study. Obecity , 23 (3) pp. 699-706. 10.1002/oby.20997. Green open access
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Ehrenstein, M; Shipa, M; Yeoh, S-A; Embleton-Thirsk, A; Mukerjee, D; (2021) The synergistic efficacy of hydroxychloroquine with methotrexate is accompanied by increased erythrocyte mean corpuscular volume. Rheumatology , 61 (2) pp. 787-793. 10.1093/rheumatology/keab403. Green open access
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Elstad, Maria; Ahmed, Saiam; Røislien, Jo; Douiri, Abdel; (2023) Evaluation of the reported data linkage process and associated quality issues for linked routinely collected healthcare data in multimorbidity research: a systematic methodology review. BMJ Open , 13 (5) , Article e069212. 10.1136/bmjopen-2022-069212. Green open access
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Embleton, AC; Clark, E; Townsend, S; Farrelly, L; Jones, C; Kaplan, R; (2015) Impact of retrospective data verification on the results of the academic-led ICON6 trial. Presented at: 3rd International Clinical Trials Methodology Conference, Glasgow, UK. Green open access
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Embleton-Thirsk, A; Deane, E; Townsend, S; Farrelly, L; Popoola, B; Parker, J; Rustin, G; ... Kaplan, R; + view all (2019) Impact of retrospective data verification to prepare the ICON6 trial for use in a marketing authorization application. Clinical Trials , 16 (5) pp. 502-511. 10.1177/1740774519862528. Green open access
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Embleton-Thirsk, Andrew; (2021) Identifying, profiling and learning from non-commercial clinical trials used in regulatory submissions. Doctoral thesis (Ph.D), UCL (University College London).

Escaned, J; Ryan, N; Mejía-Rentería, H; Cook, CM; Dehbi, HM; Alegria-Barrero, E; Alghamdi, A; ... Götberg, M; + view all (2018) Safety of the Deferral of Coronary Revascularization on the Basis of Instantaneous Wave-Free Ratio and Fractional Flow Reserve Measurements in Stable Coronary Artery Disease and Acute Coronary Syndromes. JACC: Cardiovascular Interventions , 11 (15) pp. 1437-1449. 10.1016/j.jcin.2018.05.029. Green open access
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Eysenck, W; Ammar, A; Kanthasamy, V; Freemantle, N; Veasey, RA; Patel, NR; Furniss, SS; (2019) A trial of three non-invasive blood pressure monitors compared with invasive blood pressure assessment in atrial fibrillation and sinus rhythm. International Journal of Clinical Practice , 73 (12) , Article e13410. 10.1111/ijcp.13410. Green open access
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Eysenck, W; Freemantle, N; Sulke, N; (2020) A randomized trial evaluating the accuracy of AF detection by four external ambulatory ECG monitors compared to permanent pacemaker AF detection. Journal of Interventional Cardiac Electrophysiology , 57 pp. 361-369. 10.1007/s10840-019-00515-0. Green open access
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Eysenck, W; Sulke, N; Freemantle, N; Patel, NR; Furniss, SS; Veasey, RA; (2019) The effect of atrial fibrillation intervention on nocturnal respiratory events in elderly patients with persistent AF. The Clinical Respiratory Journal , 13 (5) pp. 280-288. 10.1111/crj.13008. Green open access
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Eysenck, W; van Zalen, J; Freemantle, N; Lloyd, G; Furniss, S; Sulke, N; (2019) The hemodynamic effects of a central iliac arteriovenous anastomosis at 6 months in patients with resistant and uncontrolled hypertension. The Journal of Clinical Hypertension , 21 (9) pp. 1399-1405. 10.1111/jch.13646. Green open access
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Eysenck, W; van Zalen, J; Freemantle, N; Lloyd, G; Furniss, S; Sulke, N; (2019) Central arteriovenous anastomosis for the treatment of patients with uncontrolled hypertension and paroxysmal AF. [Letter]. American Heart Journal , 207 pp. 86-87. 10.1016/j.ahj.2018.09.010. Green open access
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Falcaro, M; Ben-Shlomo, Y; King, M; Freemantle, N; Walters, K; (2019) Factors associated with discontinuation of antidepressant treatment after a single prescription among patients aged 55 or over: evidence from English primary care. Social Psychiatry and Psychiatric Epidemiology , 54 pp. 1545-1553. 10.1007/s00127-019-01678-x. Green open access
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Farris, O; Royston, R; Absoud, M; Ambler, G; Barnes, J; Hunter, R; Kyriakopoulos, M; ... Hassiotis, A; + view all (2020) Clinical and cost effectiveness of a parent mediated intervention to reduce challenging behaviour in pre-schoolers with moderate to severe intellectual disability (EPICC-ID) study protocol: a multi-centre, parallel-group randomised controlled trial. BMC Psychiatry , 20 , Article 35. 10.1186/s12888-020-2451-6. Green open access
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Feliciano, Josephine Louella; McLoone, Dylan; Xu, Yingxin; Quek, Ruben GW; Kuznik, Andreas; Pouliot, Jean-Francois; Gullo, Giuseppe; ... Freemantle, Nick; + view all (2023) Impact of the treatment crossover design on comparative efficacy in EMPOWER-Lung 1: Cemiplimab monotherapy as first-line treatment of advanced non-small cell lung cancer. Frontiers in Oncology , 12 , Article 1081729. 10.3389/fonc.2022.1081729. Green open access
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Fletcher, K; Mant, J; McManus, R; Campbell, S; Betts, J; Taylor, C; Virdee, S; ... Hobbs, FDR; + view all (2010) Protocol for Past BP: a randomised controlled trial of different blood pressure targets for people with a history of stroke of transient ischaemic attack (TIA) in primary care. BMC CARDIOVASC DISOR , 10 , Article 37. 10.1186/1471-2261-10-37. Green open access
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Founti, P; Bunce, C; Khawaja, AP; Doré, CJ; Mohamed-Noriega, J; Garway-Heath, DF; United Kingdom Glaucoma Treatment Study Group; (2020) Risk factors for visual field deterioration in the United Kingdom Glaucoma Treatment Study. Ophthalmology , 127 (12) pp. 1642-1651. 10.1016/j.ophtha.2020.06.009. Green open access
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Fowler, D; Hodgekins, J; French, P; Marshall, M; Freemantle, N; McCrone, P; Everard, L; ... Birchwood, M; + view all (2018) Social recovery therapy in combination with early intervention services for enhancement of social recovery in patients with first-episode psychosis (SUPEREDEN3): a single-blind, randomised controlled trial. Lancet Psychiatry , 5 (1) pp. 41-50. 10.1016/S2215-0366(17)30476-5. Green open access
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Freemantle, N; Piketty, C; (2021) Efficacy and Safety of Nemolizumab for Treatment of Adult Atopic Dermatitis. Journal of Investigational Allergology and Clinical Immunology , 31 (6) pp. 528-529. 10.18176/jiaci.0727. Green open access
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Freemantle, N; Xu, Y; Wilson, FR; (2022) Corrigendum to “Network meta-analysis of immune-oncology monotherapy as first-line treatment for advanced non-small-cell lung cancer in patients with PD-L1 expression ⩾50%”. [Corrigendum]. Therapeutic Advances in Medical Oncology , 14 pp. 1-23. 10.1177/17588359221127078. Green open access
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Freemantle, Nick; Irs, Alar; (2023) Will the ROB-ME checklist prevent omission bias in meta-analyses? The bmj , 383 , Article 2653. 10.1136/bmj.p2653. Green open access
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Freemantle, Nick; Myers, Patrick O; Siepe, Matthias; (2023) Do all roads lead to Rome? Critical reassessment of the individual patient meta-analysis on bypass grafts by Gaudino et al. European Journal of Cardio-Thoracic Surgery , 63 (1) , Article ezac564. 10.1093/ejcts/ezac564. Green open access
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Freemantle, Nick; Xu, Yingxin; Wilson, Florence R; Guyot, Patricia; Chen, Chieh-; Keeping, Sam; Konidaris, Gerasimos; ... Rietschel, Petra; + view all (2022) Network meta-analysis of immune-oncology monotherapy as first-line treatment for advanced non-small-cell lung cancer in patients with PD-L1 expression ⩾50%. Therapeutic Advances in Medical Oncology , 14 pp. 1-23. 10.1177/17588359221105024. Green open access
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Freemantle, N; (2016) Author's reply to Goldacre. [Rapid communication]. British Medical Journal , 352 , Article i889. 10.1136/bmj.i889. Green open access
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Freemantle, N; Bonadonna, RC; Gourdy, P; Mauricio, D; Mueller-Wieland, D; Bigot, G; Ciocca, A; ... Bonnemaire, M; + view all (2020) Rationale and methodology for a European pooled analysis of postmarketing interventional and observational studies of insulin glargine 300 U/mL in diabetes: protocol of REALI project. BMJ Open , 10 (4) , Article e033659. 10.1136/bmjopen-2019-033659. Green open access
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Freemantle, N; Cooper, C; Roux, C; Díez-Pérez, A; Guillemin, F; Jonsson, B; Ortolani, S; ... Martinez, L; + view all (2010) Baseline observations from the POSSIBLE EU® study: Characteristics of postmenopausal women receiving bone loss medications. Archives of Osteoporosis , 5 (1-2) 61 - 72. 10.1007/s11657-010-0035-7. Green open access
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Freemantle, N; Danchin, N; Calvi-Gries, F; Vincent, M; Home, PD; (2016) Relationship of glycaemic control and hypoglycaemic episodes to 4-year cardiovascular outcomes in people with type 2 diabetes starting insulin. Diabetes, Obesity and Metabolism , 18 (2) pp. 152-158. 10.1111/dom.12598. Green open access
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Freemantle, N; Evans, M; Christensen, T; Wolden, ML; Bjorner, JB; (2013) A comparison of health-related quality of life (health utility) between insulin degludec and insulin glargine: a meta-analysis of phase 3 trials. DIABETES OBESITY & METABOLISM , 15 (6) 564 - 571. 10.1111/dom.12086. Green open access
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Freemantle, N; Ginsberg, DA; McCool, R; Fleetwood, K; Arber, M; Khalaf, K; Loveman, C; ... Glanville, J; + view all (2016) Comparative assessment of onabotulinumtoxinA and mirabegron for overactive bladder: an indirect treatment comparison. BMJ Open , 6 (2) , Article e009122. 10.1136/bmjopen-2015-009122. Green open access
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Freemantle, N; Irs, A; De Paulis, R; Pagano, D; Falk, V; Beyersdorf, F; (2019) Transcatheter versus surgical aortic valve replacement: what does the latest evidence tell us? European Journal of Cardio-Thoracic Surgery , 56 (1) pp. 7-9. 10.1093/ejcts/ezz163. Green open access
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Freemantle, N; Khalaf, K; Loveman, C; Stanisic, S; Gultyaev, D; Lister, J; Drake, M; (2016) OnabotulinumtoxinA in the treatment of overactive bladder: a cost-effectiveness analysis versus best supportive care in England and Wales. European Journal of Health Economics , 17 (7) pp. 911-921. 10.1007/s10198-015-0737-2. Green open access
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Freemantle, N; Mauricio, D; Giaccari, A; Bailey, T; Roussel, R; Franco, D; Berthou, B; ... Davies, M; + view all (2020) Real-world outcomes of treatment with insulin glargine 300 U/mL versus standard-of-care in people with uncontrolled type 2 diabetes mellitus. Current Medical Research and Opinion 10.1080/03007995.2019.1708287. Green open access
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Freemantle, N; McNulty, D; Frier, BM; (2019) Emergency hospital admissions with hypoglycaemia: analysis of hospital episode statistics in England and a UK tertiary hospital electronic health record. Presented at: 55th EASD Annual Meeting of the European Association for the Study of Diabetes, Barcelona, Spain. Green open access
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Freemantle, N; Milojevic, M; Lim, S; Fremes, S; Pagano, D; (2019) 32nd EACTS Annual Meeting clinical trials update: ART, IMPAG, MITRA-FR and COAPT. European Journal of Cardio-Thoracic Surgery , 55 (2) pp. 186-190. 10.1093/ejcts/ezy396. Green open access
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Freemantle, N; Murray, E; Khadjesari, ZCS; Hunter, R; Linke, S; (2014) Health on the Web: randomised controlled trial of online screening and brief alcohol intervention delivered in a workplace setting. [Dataset]. , Article e0127371. 10.1371/journal.pone.0127371. Green open access
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Freemantle, N; Pagano, D; (2021) Concerns with the new SYNTAX score. Lancet , 397 (10276) p. 795. 10.1016/S0140-6736(21)00223-3. Green open access
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Freemantle, N; Pagano, D; (2018) Interpretation of results of pooled analysis of individual patient data. [Letter]. The Lancet , 392 (10150) p. 817. 10.1016/S0140-6736(18)31786-0. Green open access
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Freemantle, N; Pagano, D; (2018) Randomized trials and propensity score analyses in transcatheter aortic valve replacement: how should we interpret the results? European Journal of Cardio-Thoracic Surgery , 53 (6) pp. 1108-1111. 10.1093/ejcts/ezy120. Green open access
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Freemantle, N; Rait, G; (2015) Catalogue of errors in papers reporting clinical trials. BMJ , 351 , Article h4843. 10.1136/bmj.h4843. Green open access
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Freemantle, N; Ray, D; Falcaro, M; McNulty, D; Shallcross, L; Wood, J; Pagano, D; (2016) BMI upon discharge from hospital and its relationship with survival: an observational study utilising linked patient records. Journal of the Royal Society of Medicine , 109 (6) pp. 230-238. 10.1177/0141076816639047. Green open access
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Freemantle, N; Ray, D; McNulty, D; Rosser, D; Bennett, S; Keogh, BE; Pagano, D; (2015) Increased mortality associated with weekend hospital admission: a case for expanded seven day services? British Medical Journal , 351 , Article h4596. 10.1136/bmj.h4596. Green open access
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Freemantle, N; Ruel, M; Gaudino, MFL; Pagano, D; (2018) On the pooling and subgrouping of data from percutaneous coronary intervention versus coronary artery bypass grafting trials: a call to circumspection. On the pooling and subgrouping of data from percutaneous coronary intervention versus coronary artery bypass grafting trials: a call to circumspection , 53 (5) pp. 915-918. 10.1093/ejcts/ezy140. Green open access
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Freemantle, N; Slee, A; Nazareth, I; (2019) Pharmacological treatments for generalised anxiety disorder – Authors' reply. [Letter]. The Lancet , 394 (10205) p. 1230. 10.1016/S0140-6736(19)31415-1. Green open access
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Freemantle, N; Strack, TR; Real World Trialists; (2006) Will availability of inhaled human insulin (Exubera (R)) improve management of type 2 diabetes? The design of the Real World trial. Trials , 7 , Article 25. 10.1186/1745-6215-7-25. Green open access
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Fritszching, Benedikt; Porsbjerg, Celeste; Buchs, Sarah; Larsen, Julie Rask; Freemantle, Nick; Contoli, Marco; (2023) High baseline prevalence of atopic comorbidities and medication use in children treated with allergy immunotherapy in the REAl-world effeCtiveness in allergy immunoTherapy (REACT) study. Frontiers in Pediatrics , 11 , Article 1136942. 10.3389/fped.2023.1136942. Green open access
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Fritzsching, Benedikt; Contoli, Marco; Porsbjerg, Celeste; Buchs, Sarah; Larsen, Julie Rask; Elliott, Lisa; Rodriguez, Mercedes Romano; (2022) Long-term real-world effectiveness of allergy immunotherapy in patients with allergic rhinitis and asthma: Results from the REACT study, a retrospective cohort study. The Lancet Regional Health - Europe , 13 , Article 100275. 10.1016/j.lanepe.2021.100275. Green open access
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Fritzsching, Benedikt; Contoli, Marco; Porsbjerg, Celeste; Buchs, Sarah; Larsen, Julie Rask; Elliott, Lisa; Romano, Mercedes; (2022) Need for longitudinal studies to assess the real-world effectiveness of allergy immunotherapy in patients with allergic rhinitis and asthma - Authors's reply. The Lancet Regional Health - Europe , 17 , Article 100388. 10.1016/j.lanepe.2022.100388. Green open access
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Fritzsching, Benedikt; Contoli, Marco; Porsbjerg, Celeste; Buchs, Sarah; Larsen, Julie Rask; Freemantle, Nick; (2022) Real-world evidence: Methods for assessing long-term health and effectiveness of allergy immunotherapy. Journal of Allergy and Clinical Immunology , 149 (3) pp. 881-883. 10.1016/j.jaci.2021.12.781. Green open access
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Gafoor, Rafael; (2024) A Comprehensive Guide to Coding and Programming in Stata: Introduction. In: A Comprehensive Guide to Coding and Programming in Stata. (pp. 1-5). Taylor & Francis: Abingdon, UK. Green open access
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Gamble, Carrol; Lewis, Steff; Stocken, Deborah; Juszczak, Edmund; Bradburn, Mike; Doré, Caroline; Kean, Sharon; (2023) Determining a risk-proportionate approach to the validation of statistical programming for clinical trials. Clinical Trials 10.1177/17407745231204036. (In press). Green open access
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Gamble, C; Krishan, A; Stocken, D; Lewis, S; Juszczak, E; Dore, C; Williamson, PR; ... Loder, E; + view all (2017) Guidelines for the Content of Statistical Analysis Plans in Clinical Trials. JAMA - Journal of the American Medical Association , 318 (23) pp. 2337-2343. 10.1001/jama.2017.18556.

Garattini, L; Freemantle, N; Nobili, A; Mannucci, PM; (2023) Conceptualizing a model for European health systems: the institutional framework. Internal and Emergency Medicine , 18 pp. 1213-1215. 10.1007/s11739-023-03261-4. Green open access
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Garattini, Livio; Badinella Martini, Marco; Freemantle, Nick; Nobili, Alessandro; Mannucci, Pier Mannuccio; (2023) A European national health and social service model: imagining a rational philosophy for health care organizations. Internal and Emergency Medicine , 18 pp. 2435-2437. 10.1007/s11739-023-03409-2. Green open access
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Garattini, Livio; Bozzetto, Michela; Remuzzi, Giuseppe; Freemantle, Nick; Nobili, Alessandro; (2022) Primary care in a National Health Service: time for radical reform. Family Practice , 39 (5) pp. 994-995. 10.1093/fampra/cmac019. Green open access
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Garattini, Livio; Freemantle, Nick; Nobili, Alessandro; Mannucci, Pier Mannuccio; (2023) A European national health and social service model: a few rules of the game. Internal and Emergency Medicine , 18 pp. 1583-1585. 10.1007/s11739-023-03301-z. Green open access
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Garattini, Livio; Martini, Marco Badinella; Freemantle, Nicholas; Nobili, Alessandro; Mannucci, Pier Mannuccio; (2023) A European national health and social service model: a rational network of health care facilities. Internal and Emergency Medicine , 18 pp. 1855-1857. 10.1007/s11739-023-03342-4. Green open access
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Garattini, Livio; Martini, Marco Badinella; Freemantle, Nick; Nobili, Alessandro; (2022) Integrated care in a National Health Service: better horizontal than vertical for general practice? Family Practice , 39 (6) pp. 1194-1195. 10.1093/fampra/cmac046. Green open access
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Garattini, L; Curto, A; Freemantle, N; (2016) Vaccination planning in Italy: increasing vaccines while reducing coverage? Expert Review of Pharmacoeconomics & Outcomes Research , 16 (5) pp. 547-548. 10.1080/14737167.2016.1215918. Green open access
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Garattini, L; Curto, A; Padula, A; Freemantle, N; (2016) Real-world evidence in economic evaluations: really realistic? Journal of The Royal Society Of Medicine , 109 (11) pp. 404-407. 10.1177/0141076816671258. Green open access
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Garattini, L; Padula, A; Freemantle, N; (2021) Do European pharmacists really have to trespass on medicine? The European Journal of Health Economics , 22 pp. 1-4. 10.1007/s10198-020-01185-w. Green open access
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Garattini, L; Padula, A; Freemantle, N; (2020) Pricing vaccines and drugs in Europe: worth differentiating? The European Journal of Health Economics 10.1007/s10198-020-01211-x. (In press). Green open access
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Garattini, L; Zanetti, M; Freemantle, N; (2020) The Italian NHS: What Lessons to Draw from COVID-19? Applied Health Economics and Health Policy 10.1007/s40258-020-00594-5. (In press). Green open access
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Gaudino, Mario; Flather, Marcus; Capodanno, Davide; Milojevic, Milan; Bhatt, Deepak L; Zoccai, Giuseppe Biondi; Boden, William E; ... Sandner, Sigrid; + view all (2024) European Association of Cardio-Thoracic Surgery (EACTS) expert consensus statement on perioperative myocardial infarction after cardiac surgery. European Journal of Cardio-Thoracic Surgery , 65 (2) , Article ezad415. 10.1093/ejcts/ezad415. Green open access
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Gaudino, Mario; Freemantle, Nick; Sadaba, Rafael; (2023) In memoriam: Professor Domenico Pagano. European Heart Journal , 44 (5) pp. 338-339. 10.1093/eurheartj/ehac725. Green open access
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Gaudino, M; Freemantle, N; Farkouh, ME; (2020) The conundrum of the treatment for left main coronary disease. European Heart Journal , 41 (34) pp. 3236-3238. 10.1093/eurheartj/ehaa318. Green open access
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Gaudino, M; Pagano, D; Freemantle, N; (2020) Commentary: The left main controversy: Is this a real subgroup requiring custom clinical recommendations? The Journal of Thoracic and Cardiovascular Surgery 10.1016/j.jtcvs.2020.04.102. (In press). Green open access
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Geddes, J; Freemantle, N; Harrison, P; Bebbington, P; Natl Schizophrenia Guideline Dev; (2000) Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta-regression analysis. BRIT MED J , 321 (7273) 1371 - 1376. Green open access
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Gee, B; Hodgekins, J; Fowler, D; Marshall, M; Everard, L; Lester, H; Jones, PB; ... Birchwood, M; + view all (2016) The course of negative symptom in first episode psychosis and the relationship with social recovery. Schizophrenia Research , 174 (1-3) pp. 165-171. 10.1016/j.schres.2016.04.017. Green open access
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Gee, B; Hodgekins, J; Lavis, A; Notley, C; Birchwood, M; Everard, L; Freemantle, N; ... Fowler, D; + view all (2019) Lived experiences of negative symptoms in first-episode psychosis: A qualitative secondary analysis. Early Intervention in Psychiatry , 13 (4) pp. 773-779. 10.1111/eip.12558. Green open access
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Gill, PS; Beavan, J; Calvert, M; Freemantle, N; (2011) The Unmet Need for Interpreting Provision in UK Primary Care. PLOS ONE , 6 (6) , Article e20837. 10.1371/journal.pone.0020837. Green open access
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Gill, PS; Calvert, M; Davis, R; Davies, MK; Freemantle, N; Lip, GY; (2011) Prevalence of heart failure and atrial fibrillation in minority ethnic subjects: the Ethnic-Echocardiographic Heart of England Screening Study (E-ECHOES). PLOS One , 6 (11) , Article e26710. 10.1371/journal.pone.0026710. Green open access
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Gill, PS; Davis, R; Davies, M; Freemantle, N; Lip, GYH; (2009) Rationale and study design of a cross sectional study documenting the prevalence of Heart Failure amongst the minority ethnic communities in the UK: the E-ECHOES Study (Ethnic - Echocardiographic Heart of England Screening Study). BMC CARDIOVASC DISOR , 9 , Article 47. 10.1186/1471-2261-9-47. Green open access
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Gill, PS; Shankar, A; Quirke, T; Freemantle, N; (2009) Access to interpreting services in England: secondary analysis of national data. BMC Public Health , 9 , Article 12. 10.1186/1471-2458-9-12. Green open access
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Gilson, R; Nugent, D; Bennett, K; Dore, C; Murray, M; Meadows, J; Haddow, L; ... Copas, A; + view all (2020) Imiquimod versus podophyllotoxin, with and without human papillomavirus vaccine, for anogenital warts: the HIPvac factorial RCT. Health Technology Assessment , 24 (47) 10.3310/hta24470. Green open access
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Girges, C; Vijiaratnam, N; Athauda, D; Auld, G; Gandhi, S; Foltynie, T; (2021) The Future of Incretin-Based Approaches for Neurodegenerative Diseases in Older Adults: Which to Choose? A Review of their Potential Efficacy and Suitability. Drugs & Aging , 38 pp. 355-373. 10.1007/s40266-021-00853-7. Green open access
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Goldberg, Andrew J; Bordea, Ekaterina; Chowdhury, Kashfia; Hauptmannova, Iva; Blackstone, James; Brooking, Deirdre; Deane, Elizabeth L; ... TARVA Study, Group; + view all (2024) Cost-Utility Analysis of Total Ankle Replacement Compared with Ankle Arthrodesis for Patients Aged 50-85 Years with End-Stage Ankle Osteoarthritis: The TARVA Study. PharmacoEconomics - Open 10.1007/s41669-023-00449-4. (In press). Green open access
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Goldberg, Andrew J; Chowdhury, Kashfia; Bordea, Ekaterina; Blackstone, James; Brooking, Deirdre; Deane, Elizabeth L; Hauptmannova, Iva; ... Doré, Caroline J; + view all (2023) Total ankle replacement versus ankle arthrodesis for patients aged 50-85 years with end-stage ankle osteoarthritis: the TARVA RCT. Health Technology Assessment , 27 (5) 10.3310/PTYJ1146. Green open access
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Goldberg, Andrew J; Chowdhury, Kashfia; Bordea, Ekaterina; Hauptmannova, Iva; Blackstone, James; Brooking, Deirdre; Deane, Elizabeth L; ... TARVA Study Group†; + view all (2022) Total Ankle Replacement Versus Arthrodesis for End-Stage Ankle Osteoarthritis : A Randomized Controlled Trial. Annals of Internal Medicine 10.7326/M22-2058. (In press).

Goldberg, AJ; Zaidi, R; Thomson, C; Doré, CJ; Skene, SS; Cro, S; Round, J; ... TARVA study group, .; + view all (2016) Total ankle replacement versus arthrodesis (TARVA): protocol for a multicentre randomised controlled trial. BMJ Open , 6 (9) , Article e012716. 10.1136/bmjopen-2016-012716. Green open access
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Gomes, Manuel; Latimer, Nick; Soares, Marta; Dias, Sofia; Baio, Gianluca; Freemantle, Nick; Dawoud, Dalia; ... Grieve, Richard; + view all (2022) Target Trial Emulation for Transparent and Robust Estimation of Treatment Effects for Health Technology Assessment Using Real-World Data: Opportunities and Challenges. PharmacoEconomics , 40 pp. 577-586. 10.1007/s40273-022-01141-x. Green open access
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González Martín, A; Oza, A; Embleton, AC; Pfisterer, J; Ledermann, J; Pujade-Lauraine, E; Kristensen, G; ... Perren, T; + view all (2019) Exploratory outcome analyses according to stage and/or residual disease in the ICON7 trial of carboplatin and paclitaxel with or without bevacizumab for newly diagnosed ovarian cancer. Gynecologic Oncology , 152 (1) 10.1016/j.ygyno.2018.08.036. Green open access
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Goranitis, I; Coast, J; Day, E; Copello, A; Freemantle, N; Frew, E; (2017) Maximizing Health or Sufficient Capability in Economic Evaluation? A Methodological Experiment of Treatment for Drug Addiction. Medical Decision Making , 37 (5) pp. 498-511. 10.1177/0272989X16678844. Green open access
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Goranitis, I; Coast, J; Day, E; Copello, A; Freemantle, N; Seddon, J; Bennett, C; (2016) Measuring Health and Broader Well-Being Benefits in the Context of Opiate Dependence: The Psychometric Performance of the ICECAP-A and the EQ-5D-5L. Value in Health , 19 (6) pp. 820-828. 10.1016/j.jval.2016.04.010. Green open access
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Goring, S; Taylor, A; Mueller, K; Li, TJJ; Korol, EE; Levy, AR; Freemantle, N; (2019) Characteristics of non-randomised studies using comparisons with external controls submitted for regulatory approval in the USA and Europe: a systematic review. BMJ Open , 9 (2) , Article e024895. 10.1136/bmjopen-2018-024895. Green open access
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Gourdy, P; Bonadonna, RC; Freemantle, N; Mauricio, D; Mueller-Wieland, D; Bigot, G; Mauquoi, C; ... Bonnemaire, M; + view all (2021) Does Gender Influence the Effectiveness and Safety of Insulin Glargine 300 U/ml in Patients with Uncontrolled Type 2 Diabetes? Results from the REALI European Pooled Analysis. Diabetes Therapy 10.1007/s13300-021-01179-8. (In press). Green open access
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Gourdy, Pierre; Bonadonna, Riccardo C; Mauricio, Didac; Müller-Wieland, Dirk; Mauquoi, Celine; Vera, Carine; Bonnemaire, Mireille; (2024) Effectiveness and safety of insulin glargine 300 U/mL in insulin-naïve individuals according to diabetes duration: Results from the REALI European pooled data analysis. Diabetes, Obesity and Metabolism 10.1111/dom.16008. (In press). Green open access
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Graham, HL; Copello, A; Griffith, E; Freemantle, N; McCrone, P; Clarke, L; Walsh, K; ... Birchwood, M; + view all (2016) Pilot randomised trial of a brief intervention for comorbid substance misuse in psychiatric in-patient settings. Acta Psychiatrica Scandinavica , 133 (4) pp. 298-309. 10.1111/acps.12530. Green open access
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Griffiths, SL; Bogatsu, T; Longhi, M; Butler, E; Alexander, B; Bandawar, M; Everard, L; ... Upthegrove, R; + view all (2023) Five-year illness trajectories across racial groups in the UK following a first episode psychosis. Social Psychiatry and Psychiatric Epidemiology 10.1007/s00127-023-02428-w. (In press). Green open access
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Griffiths, SL; Leighton, SP; Mallikarjun, PK; Blake, G; Everard, L; Jones, PB; Fowler, D; ... Upthegrove, R; + view all (2021) Structure and stability of symptoms in first episode psychosis: a longitudinal network approach. Translational Psychiatry , 11 , Article 567. 10.1038/s41398-021-01687-y. Green open access
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Griffiths, SL; Wood, SJ; Fowler, D; Freemantle, N; Hodgekins, J; Jones, PB; Singh, S; ... Birchwood, M; + view all (2021) Improved social functioning following social recovery therapy in first episode psychosis: Do social cognition and neurocognition change following therapy, and do they predict treatment response? Schizophrenia Research , 228 pp. 249-255. 10.1016/j.schres.2020.12.023. Green open access
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Guest, J; Ovcinnikova, O; Panca, M; (2015) Cost-effectiveness of using an extensively hydrolyzed casein formula plus the probiotic Lactobacillus rhamnosus GG compared to an extensively hydrolyzed formula alone or an amino acid formula as first-line dietary management for cow’s milk allergy in the US. ClinicoEconomics and Outcomes Research , 7 pp. 145-51. 10.2147/CEOR.S75071. Green open access
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Guest, J; Panca, M; Ovcinnikova, O; Nocerino, R; (2015) Relative cost-effectiveness of an extensively hydrolyzed casein formula containing the probiotic Lactobacillus rhamnosus GG in managing infants with cow’s milk allergy in Italy. ClinicoEconomics and Outcomes Research pp. 325-336. 10.2147/CEOR.S80130. Green open access
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Guest, JF; Panca, M; Sladkevicius, E; Gough, N; Linch, M; (2013) Cost Effectiveness of First-Line Treatment with Doxorubicin/Ifosfamide Compared to Trabectedin Monotherapy in the Management of Advanced Soft Tissue Sarcoma in Italy, Spain, and Sweden. Sarcoma , 2013 pp. 1-19. 10.1155/2013/725305. Green open access
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Guest, JF; Panca, M; Sladkevicius, E; Taheri, S; Stradling, J; (2014) Clinical Outcomes and Cost- effectiveness of Continuous Positive Airway Pressure to Manage Obstructive Sleep Apnea in Patients With Type 2Diabetes in the U. K. Diabetes Care , 37 (5) pp. 1263-1271. 10.2337/dc13-2539. Green open access
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Guja, Cristian; Kis, Janos Tibor; Haluzik, Martin; Bonnemaire, Mireille; Bigot, Gregory; Tournay, Mathilde; Freemantle, Nick; (2023) iGlarLixi (insulin glargine 100 U/ml plus lixisenatide) is effective and well tolerated in people with uncontrolled type 2 diabetes regardless of age: A REALI pooled analysis of prospective real-world data. Diabetes, Obesity and Metabolism 10.1111/dom.15027. (In press). Green open access
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Hague, D; Townsend, S; Masters, L; Rauchenberger, M; Van Looy, N; Diaz Montana, C; Gannon, M; ... Sydes, M; + view all (2019) Changing platforms without stopping the train: experiences of data management and data management systems when adapting platform protocols by adding and closing comparisons. Trials , 20 , Article 294. 10.1186/s13063-019-3322-7. Green open access
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Hall, MR; Dehbi, H-M; Banerjee, S; Lord, R; Clamp, A; Ledermann, JA; Nicum, S; ... Rustin, G; + view all (2020) A phase II randomised, placebo-controlled trial of low dose (metronomic) cyclophosphamide and nintedanib (BIBF1120) in advanced ovarian, fallopian tube or primary peritoneal cancer. Gynecologic Oncology , 159 (3) pp. 692-698. 10.1016/j.ygyno.2020.09.048. Green open access
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Halonen, JI; Dehbi, H-M; Hansell, AL; Gulliver, J; Fecht, D; Blangiardo, M; Kelly, FJ; ... Tonne, C; + view all (2017) Associations of night-time road traffic noise with carotid intima-media thickness and blood pressure: The Whitehall II and SABRE study cohorts. Environment International , 98 pp. 54-61. 10.1016/j.envint.2016.09.023. Green open access
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Haluzik, Martin; Seufert, Jochen; Guja, Cristian; Bonnemaire, Mireille; Bigot, Gregory; Tournay, Mathilde; Kis, Janos T; (2022) Effectiveness of iGlarLixi (Insulin Glargine-Lixisenatide) in People with Type 2 Diabetes According to the Time of Administration through the Day. Presented at: UNSPECIFIED. Green open access
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Haluzik, Martin; Seufert, Jochen; Guja, Cristian; Bonnemaire, Mireille; Bigot, Gregory; Tournay, Mathilde; Kis, Janos Tibor; (2023) Effectiveness and Safety of iGlarLixi (Insulin Glargine 100 U/mL Plus Lixisenatide) in Type 2 Diabetes According to the Timing of Daily Administration: Data from the REALI Pooled Analysis. Diabetes Therapy 10.1007/s13300-023-01375-8. (In press). Green open access
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Halvorsen, AR; Kristensen, G; Embleton, A; Adusei, C; Pilar Barretina-Ginesta, M; Beale, P; Helland, A; (2017) Evaluation of Prognostic and Predictive Significance of Circulating MicroRNAs in Ovarian Cancer Patients. Disease Markers , Article 3098542. 10.1155/2017/3098542. Green open access
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Hanh, N; Ahmed, K; Luo, W; Flint, J; Giles, I; (2021) A Systematic Review of the safety of non-TNF inhibitor biologic and targeted synthetic drugs in rheumatic disease in pregnancy. Seminars in Arthritis and Rheumatism , 51 (6) pp. 1-13. 10.1016/j.semarthrit.2021.09.004. Green open access
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Hassan, A; Balal, S; Cook, E; Dehbi, HM; Pardhan, S; Bourne, R; Ahmad, S; (2022) Finger-Prick Autologous Blood (FAB) Eye Drops for Dry Eye Disease: Single Masked Multi-Centre Randomised Controlled Trial. Clinical Ophthalmology , 16 pp. 3973-3979. 10.2147/OPTH.S384586. Green open access
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Hatswell, A; Freemantle, N; Baio, G; Lesaffre, E; van Rosmalen, J; (2020) Summarising salient information on historical controls: A structured assessment of validity and comparability across studies. Clinical Trials 10.1177/1740774520944855. (In press). Green open access
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Hatswell, AJ; Baio, G; Berlin, JA; Irs, A; Freemantle, N; (2016) Regulatory approval of pharmaceuticals without a randomised controlled study: analysis of EMA and FDA approvals 1999-2014. BMJ Open , 6 (6) , Article e011666. 10.1136/bmjopen-2016-011666. Green open access
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Hatswell, AJ; Freemantle, N; Baio, G; (2020) The Effects of Model Misspecification in Unanchored Matching-Adjusted Indirect Comparison (MAIC): Results of a Simulation Study. Value in Health , 23 (6) pp. 751-759. 10.1016/j.jval.2020.02.008. Green open access
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Hatswell, AJ; Freemantle, N; Baio, G; (2016) Economic Evaluations of Pharmaceuticals Granted a Marketing Authorisation Without the Results of Randomised Trials: A Systematic Review and Taxonomy. PharmacoEconomics , 35 (2) pp. 163-176. 10.1007/s40273-016-0460-6. Green open access
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Hawarden, Amy; Price, Marcus; Russell, Bryn; Wilson, Godfrey; Farrelly, Laura; Embleton-Thirsk, Andrew; Parmar, Mahesh; (2023) A three protein signature fails to externally validate as a biomarker to predict surgical outcome in high-grade epithelial ovarian cancer. PLoS ONE , 18 (3) , Article e0281798. 10.1371/journal.pone.0281798. Green open access
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Hayes, Aimee R; Furnace, Myles; Shah, Ruchir; Rundell, Caroline; Muller, Gregory; Dehbi, Hakim-Moulay; Tu, Vinh Luong; ... Mandair, Dalvinder; + view all (2021) High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms and Improved Prognostic Stratification With the New World Health Organization 2019 Classification A Validation Study From a Single-Institution Retrospective Analysis. Pancreas , 50 (4) pp. 516-523. 10.1097/MPA.0000000000001808. Green open access
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Heightman, M; Prashar, J; Hillman, TE; Marks, M; Livingston, R; Ridsdale, HA; Bell, R; ... Banerjee, A; + view all (2021) Post-COVID-19 assessment in a specialist clinical service: a 12-month, single-centre, prospective study in 1325 individuals. BMJ Open Respiratory Research , 8 (1) , Article e001041. 10.1136/bmjresp-2021-001041. Green open access
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Hinchliffe, RF; Mahon, A; Thomas, W; Doré, CJ; Briggs, C; De la Salle, B; Hyde, K; (2016) Results of a prepilot study of potential test material for the external quality assessment of reticulocyte haemoglobin content. International Journal of Laboratory Hematology , 38 (4) e86-e88. 10.1111/ijlh.12514. Green open access
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Hobbs, AJ; Moyes, AJ; Baliga, RS; Ghedia, D; Ochiel, R; Sylvestre, Y; Doré, CJ; ... MacAllister, RJ; + view all (2019) Neprilysin inhibition for pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled, proof-of-concept trial. British Journal of Pharmacology , 176 (9) pp. 1251-1267. 10.1111/bph.14621. Green open access
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Hockey, Leanne Nicole; (2020) Tourette's syndrome: The role of attention and inhibitory mechanisms in the generation and management of tics. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Hodgekins, J; Birchwood, M; Christopher, R; Marshall, M; Coker, S; Everard, L; Lester, H; ... Fowler, D; + view all (2015) Investigating trajectories of social recovery in individuals with first episode psychosis: a latent class growth analysis. British Journal of Psychiatry , 207 (3) pp. 1-8. 10.1192/bjp.bp.114.153486. Green open access
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Home, P; Calvi-Gries, F; Blonde, L; Pilorget, V; Berlingieri, J; Freemantle, N; (2017) Clinical correlates of hypoglycaemia over 4 years in people with type 2 diabetes starting insulin: An analysis from the CREDIT study. Diabetes, Obesity and Metabolism , 20 (4) pp. 921-929. 10.1111/dom.13179. Green open access
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Horne, R; Chapman, SC; Parham, R; Freemantle, N; Forbes, A; Cooper, V; (2013) Understanding Patients' Adherence-Related Beliefs about Medicines Prescribed for Long-Term Conditions: A Meta-Analytic Review of the Necessity-Concerns Framework. PLoS One , 8 (12) , Article e80633. 10.1371/journal.pone.0080633. Green open access
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Howard, Robert; Cort, Elizabeth; Rawlinson, Charlotte; Wiegand, Martin; Downey, Anne; Lawrence, Vanessa; Banerjee, Sube; ... Gould, Rebecca; + view all (2024) Adapted problem adaptation therapy for depression in mild to moderate Alzheimer's disease dementia: A randomized controlled trial. Alzheimer's & Dementia 10.1002/alz.13766. (In press). Green open access
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Hunter, Elaine CM; Wong, Cheuk Lon Malcolm; Gafoor, Rafael; Lewis, Glyn; David, Anthony S; (2023) Cognitive Behaviour Therapy (CBT) for Depersonalization Derealization Disorder (DDD): a self-controlled cross-over study of waiting list vs. active treatment. Cognitive Behaviour Therapy 10.1080/16506073.2023.2255744. (In press). Green open access
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Hunter, R; Wallace, P; Struzzo, P; Vedova, RD; Scafuri, F; Tersar, C; Lygidakis, C; ... Freemantle, N; + view all (2017) Randomised controlled non-inferiority trial of primary care-based facilitated access to an alcohol reduction website: cost-effectiveness analysis. BMJ Open , 7 (11) , Article e014577. 10.1136/bmjopen-2016-014577. Green open access
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Hunter, RM; Baio, G; Butt, T; Morris, S; Round, J; Freemantle, N; (2015) An Educational Review of the Statistical Issues in Analysing Utility Data for Cost-Utility Analysis. Pharmacoeconomics (33) , Article 4. 10.1007/s40273-014-0247-6. Green open access
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Ibrahim, F; Choy, E; Gordon, P; Doré, CJ; Hakim, A; Kitas, G; Isenberg, D; ... Scott, DL; + view all (2014) Second-line agents in myositis: 1-year factorial trial of additional immunosuppression in patients who have partially responded to steroids. Rheumatology (Oxford) , 54 (6) pp. 1050-1055. 10.1093/rheumatology/keu442. Green open access
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Ibrahim, F; Lorente-Cánovas, B; Doré, CJ; Bosworth, A; Ma, MH; Galloway, JB; Cope, AP; ... Scott, DL; + view all (2017) Optimizing treatment with tumour necrosis factor inhibitors in rheumatoid arthritis-a proof of principle and exploratory trial: is dose tapering practical in good responders? Rheumatology , 56 (11) pp. 2004-2014. 10.1093/rheumatology/kex315. Green open access
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This list was generated on Fri Oct 3 01:16:07 2025 BST.