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A trial of three non-invasive blood pressure monitors compared with invasive blood pressure assessment in atrial fibrillation and sinus rhythm

Eysenck, W; Ammar, A; Kanthasamy, V; Freemantle, N; Veasey, RA; Patel, NR; Furniss, SS; (2019) A trial of three non-invasive blood pressure monitors compared with invasive blood pressure assessment in atrial fibrillation and sinus rhythm. International Journal of Clinical Practice , 73 (12) , Article e13410. 10.1111/ijcp.13410. Green open access

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Abstract

OBJECTIVE: To investigate the accuracy of three non‐invasive blood pressure (BP) devices in atrial fibrillation (AF) compared with invasive arterial BP. METHODS: One hundred patients aged 45‐90 years, 63% male (50 in AF and 50 age matched controls in sinus rhythm [SR]) were identified with arterial lines measuring beat‐to‐beat BP fluctuation. Non‐invasive BP measurements utilising the manual sphygmomanometer (MS), PulseCor R6.5 (PC) and automated sphygmomanometer (AS) were taken simultaneously with invasive BP in a randomised sequence. This was repeated three times in each patient. RESULTS: In SR differences in systolic BP (SBP) for MS, AS and PC were −0.34 mm Hg (95% CI −2.31 to 1.63; P = .733), −3.80 mm Hg (95% CI −5.73 to −1.87; P = .0001) and −3.90 mm Hg (95% CI −5.90 to −1.90; P = .0001) and for diastolic BP (DBP) were 6.02 mm Hg (95% CI 4.39‐7.64; P < .0001), 8.95 mm Hg (95% CI 7.36‐10.55; P < .0001) and 7.54 mm Hg (95% CI 5.89‐9.18; P < .0001), respectively. In AF mean differences in SBP for MS, AS and PC were −7.33 mm Hg (95% CI −9.11 to −5.55; P < .0001), −5.29 mm Hg (95% CI −7.08 to −3.50; P < .0001) and −5.75 mm Hg (95% CI −7.54 to −3.96; P < .0001) respectively and for DBP were 5.28 mm Hg (95% CI 4.03‐6.54; P < .0001), 6.26 mm Hg (95% CI 5.00‐7.52; P < .0001) and 6.89 mm Hg (95% CI 5.64‐8.15; P < .0001) respectively. CONCLUSIONS: The MS is accurate in SR because of direct assessment of Korotkoff sounds. Non‐invasive BP assessment in AF is significantly less accurate. These findings have important prognostic and therapeutic implications.

Type: Article
Title: A trial of three non-invasive blood pressure monitors compared with invasive blood pressure assessment in atrial fibrillation and sinus rhythm
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/ijcp.13410
Publisher version: https://doi.org/10.1111/ijcp.13410
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > Comprehensive CTU at UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10084598
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