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Functional hemispheric asymmetry and nicotine dependency as variables mediating neurobiological vulnerability to schizotypy in a non-clinical population of college students

Zartaloudi, E; Polemikou, A; (2019) Functional hemispheric asymmetry and nicotine dependency as variables mediating neurobiological vulnerability to schizotypy in a non-clinical population of college students. Personality and Individual Differences , 137 pp. 165-172. 10.1016/j.paid.2018.09.003. Green open access

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Abstract

In the present study, schizotypal personality traits and their neuropsychological correlates were examined amongst a non-clinical sample, so as to gain insight into the variables mediating neurobiological vulnerability to schizotypy. To that effect, 50 young adults completed the Oxford-Liverpool Inventory of Feelings and Experiences, the Fagerström Test of Nicotine Dependence, the Edinburgh Handedness Questionnaire, and a dichotic listening task. Analyses revealed a significant right-hemisphere dominance association to positive schizotypy, and a left-hemisphere dominance association to negative schizotypy. Nicotine dependence emerged as a significant correlate of positive and overall schizotypy, and left-hemisphere dominance. Gender-based interactions were significant for females on positive schizotypy, nicotine dependence and right-hemisphere dominance, and on negative schizotypy for males. The findings of this study can be used to advance our understanding of the factors of risk and resilience in the schizophrenia spectrum.

Type: Article
Title: Functional hemispheric asymmetry and nicotine dependency as variables mediating neurobiological vulnerability to schizotypy in a non-clinical population of college students
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.paid.2018.09.003
Publisher version: https://doi.org/10.1016/j.paid.2018.09.003
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Brain laterality, Schizotypy, Psychosis proneness, Psychotropic
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > Comprehensive CTU at UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10086119
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