Halonen, JI;
Dehbi, H-M;
Hansell, AL;
Gulliver, J;
Fecht, D;
Blangiardo, M;
Kelly, FJ;
... Tonne, C; + view all
(2017)
Associations of night-time road traffic noise with carotid intima-media thickness and blood pressure: The Whitehall II and SABRE study cohorts.
Environment International
, 98
pp. 54-61.
10.1016/j.envint.2016.09.023.
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Abstract
BACKGROUND: Road traffic noise has been linked to increased risk of stroke, for which hypertension and carotid intima-media thickness (cIMT) are risk factors. A link between traffic noise and hypertension has been established, but there are few studies on blood pressure and no studies on cIMT. OBJECTIVES: To examine cross-sectional associations for long-term exposure to night-time noise with cIMT, systolic blood pressure (SBP), diastolic blood pressure (DBP) and hypertension. METHODS: The study population consisted of 2592 adults from the Whitehall II and SABRE cohort studies living within Greater London who had cIMT, SBP and DBP measured. Exposure to night-time road traffic noise (A-weighted dB, referred to as dBA) was estimated at each participant's residential postcode centroid. RESULTS: Mean night-time road noise levels were 52 dBA (SD = 4). In the pooled analysis adjusted for cohort, sex, age, ethnicity, marital status, smoking, area-level deprivation and NOx there was a 9.1 μm (95% CI: − 7.1, 25.2) increase in cIMT in association with 10 dBA increase in night-time noise. Analyses by noise categories of 55–60 dBA (16.2 μm, 95% CI: − 8.7, 41.2), and > 60 dBA (21.2 μm, 95% CI: − 2.5, 44.9) vs. < 55 dBA were also positive but non-significant, expect among those not using antihypertensive medication and exposed to > 60 dBA vs. < 55 dBA (32.6 μm, 95% CI: 6.2, 59.0). Associations for SBP, DPB and hypertension were close to null. CONCLUSIONS: After adjustments, including for air pollution, the association between night-time road traffic noise and cIMT was only observed among non-medication users but associations with blood pressure and hypertension were largely null.
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