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Associations of night-time road traffic noise with carotid intima-media thickness and blood pressure: The Whitehall II and SABRE study cohorts

Halonen, JI; Dehbi, H-M; Hansell, AL; Gulliver, J; Fecht, D; Blangiardo, M; Kelly, FJ; ... Tonne, C; + view all (2017) Associations of night-time road traffic noise with carotid intima-media thickness and blood pressure: The Whitehall II and SABRE study cohorts. Environment International , 98 pp. 54-61. 10.1016/j.envint.2016.09.023. Green open access

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Abstract

BACKGROUND: Road traffic noise has been linked to increased risk of stroke, for which hypertension and carotid intima-media thickness (cIMT) are risk factors. A link between traffic noise and hypertension has been established, but there are few studies on blood pressure and no studies on cIMT. OBJECTIVES: To examine cross-sectional associations for long-term exposure to night-time noise with cIMT, systolic blood pressure (SBP), diastolic blood pressure (DBP) and hypertension. METHODS: The study population consisted of 2592 adults from the Whitehall II and SABRE cohort studies living within Greater London who had cIMT, SBP and DBP measured. Exposure to night-time road traffic noise (A-weighted dB, referred to as dBA) was estimated at each participant's residential postcode centroid. RESULTS: Mean night-time road noise levels were 52 dBA (SD = 4). In the pooled analysis adjusted for cohort, sex, age, ethnicity, marital status, smoking, area-level deprivation and NOx there was a 9.1 μm (95% CI: − 7.1, 25.2) increase in cIMT in association with 10 dBA increase in night-time noise. Analyses by noise categories of 55–60 dBA (16.2 μm, 95% CI: − 8.7, 41.2), and > 60 dBA (21.2 μm, 95% CI: − 2.5, 44.9) vs. < 55 dBA were also positive but non-significant, expect among those not using antihypertensive medication and exposed to > 60 dBA vs. < 55 dBA (32.6 μm, 95% CI: 6.2, 59.0). Associations for SBP, DPB and hypertension were close to null. CONCLUSIONS: After adjustments, including for air pollution, the association between night-time road traffic noise and cIMT was only observed among non-medication users but associations with blood pressure and hypertension were largely null.

Type: Article
Title: Associations of night-time road traffic noise with carotid intima-media thickness and blood pressure: The Whitehall II and SABRE study cohorts
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.envint.2016.09.023
Publisher version: http://dx.doi.org/10.1016/j.envint.2016.09.023
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Hypertension, Traffic noise, PARTICULATE AIR-POLLUTION, LONG-TERM EXPOSURE, CARDIOVASCULAR-DISEASE, HYPERTENSION, ADULTS, ATHEROSCLEROSIS, RISK, METAANALYSIS, MORTALITY, PROFILE
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Inst of Clinical Trials and Methodology > Comprehensive CTU at UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: https://discovery.ucl.ac.uk/id/eprint/1524678
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