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Article

Abbosh, Christopher; Frankell, Alexander M; Harrison, Thomas; Kisistok, Judit; Garnett, Aaron; Johnson, Laura; Veeriah, Selvaraju; ... Swanton, Charles; + view all (2023) Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA. Nature , 616 (7957) pp. 553-562. 10.1038/s41586-023-05776-4. Green open access
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Abdel-Aty, H; O'Shea, L; Amos, C; Brown, LC; Grist, E; Attard, G; Clarke, N; ... James, N; + view all (2023) The STAMPEDE2 Trial: a Site Survey of Current Patterns of Care, Access to Imaging and Treatment of Metastatic Prostate Cancer. Clinical Oncology 10.1016/j.clon.2023.07.009. (In press).

Al Bakir, Maise; Huebner, Ariana; Martínez-Ruiz, Carlos; Grigoriadis, Kristiana; Watkins, Thomas BK; Pich, Oriol; Moore, David A; ... Swanton, Charles; + view all (2023) The evolution of non-small cell lung cancer metastases in TRACERx. Nature 10.1038/s41586-023-05729-x. (In press). Green open access
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Angeles, Martina Aida; Boria, Felix; Shushkevich, Alexander B; Bizzarri, Nicolo; Theofanakis, Charalampos; Schivardi, Gabriella; Kacperczyk-Bartnik, Joanna; ... Ramirez, Pedro T; + view all (2023) Interviews conducted at the European Society of Gynaecological Oncology 2022 Congress: a ENYGO-IJGC Fellows initiative. International Journal of Gynecological Cancer , 33 (1) pp. 12-18. 10.1136/ijgc-2022-004160. Green open access
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Arend, Rebecca C; Monk, Bradley J; Shapira-Frommer, Ronnie; Haggerty, Ashley F; Alvarez, Edwin A; Amit, Amnon; Alvarez Secord, Angeles; ... OVAL/GOG-3018 Investigators; + view all (2023) Ofranergene Obadenovec (Ofra-Vec, VB-111) With Weekly Paclitaxel for Platinum-Resistant Ovarian Cancer: Randomized Controlled Phase III Trial (OVAL Study/GOG 3018). Journal of Clinical Oncology , 42 (2) pp. 170-179. 10.1200/JCO.22.02915.

Attard, G; Murphy, L; Clarke, NW; Sachdeva, A; Jones, C; Hoyle, A; Cross, W; ... McPhail, N; + view all (2023) Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy: final results from two randomised phase 3 trials of the STAMPEDE platform protocol. The Lancet Oncology , 24 (5) pp. 443-456. 10.1016/S1470-2045(23)00148-1. Green open access
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Bahri, M; Anstee, JE; Opzoomer, JW; Arnold, JN; (2023) Perivascular tumor-associated macrophages and their role in cancer progression. Essays in Biochemistry , 67 (6) pp. 919-928. 10.1042/EBC20220242. Green open access
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Barnes, Josephine L; Yoshida, Masahiro; He, Peng; Worlock, Kaylee B; Lindeboom, Rik GH; Suo, Chenqu; Pett, J Patrick; ... Nikolić, Marko Z; + view all (2023) Early human lung immune cell development and its role in epithelial cell fate. Science Immunology , 8 (90) , Article eadf9988. 10.1126/sciimmunol.adf9988. Green open access
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Bassey-Archibong, Blessing Iquo; Rajendra Chokshi, Chirayu; Aghaei, Nikoo; Kieliszek, Agata Monika; Tatari, Nazanin; McKenna, Dillon; Singh, Mohini; ... Singh, Sheila Kumari; + view all (2023) An HLA-G/SPAG9/STAT3 axis promotes brain metastases. Proceedings of the National Academy of Sciences (PNAS) , 120 (8) , Article e2205247120. 10.1073/pnas.2205247120. Green open access
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Bedran, Georges; Gasser, Hans-Christof; Weke, Kenneth; Wang, Tongjie; Bedran, Dominika; Laird, Alexander; Battail, Christophe; ... Alfaro, Javier A; + view all (2023) The Immunopeptidome from a Genomic Perspective: Establishing the Noncanonical Landscape of MHC Class I–Associated Peptides. Cancer Immunology Research , 11 (6) pp. 747-762. 10.1158/2326-6066.CIR-22-0621. Green open access
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Bewicke-Copley, Findlay; Korfi, Koorosh; Araf, Shamza; Hodkinson, Brendan; Kumar, Emil; Cummin, Thomas; Ashton-Key, Margaret; ... Fitzgibbon, Jude; + view all (2023) Longitudinal expression profiling identifies a poor risk subset of patients with ABC-type diffuse large B-cell lymphoma. Blood Advances , 7 (5) pp. 845-855. 10.1182/bloodadvances.2022007536. Green open access
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Boere, Ingrid; Vergote, Ignace; Hanssen, Rob; Jalving, Mathilde; Gennigens, Christine; Ottevanger, Petronella; van de Wouw, Yes J; ... Ledermann, Jonathan; + view all (2023) CINOVA: a phase II study of CPC634 (nanoparticulate docetaxel) in patients with platinum resistant recurrent ovarian cancer. International Journal of Gynecologic Cancer , 33 (8) pp. 1247-1252. 10.1136/ijgc-2023-004308. Green open access
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Bonaca, Marc P; Moslehi, Javid J; Ledermann, Jonathan A; Michelon, Elisabete; Wei, Caimiao; Moran, Michael; Monk, Bradley J; (2023) Left Ventricular Ejection Fraction in Patients With Ovarian Cancer Treated With Avelumab, Pegylated Liposomal Doxorubicin, or Both. The Oncologist , 28 (10) e977-e980. 10.1093/oncolo/oyad213. Green open access
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Bosse, T; Creutzberg, CL; Crosbie, EJ; Han, K; Horeweg, N; Leary, A; Kroep, JR; ... RAINBO, Res Consortium; + view all (2023) Refining adjuvant treatment in endometrial cancer based on molecular features: the RAINBO clinical trial program. International Journal of Gynecological Cancer , 33 (1) pp. 109-117. 10.1136/ijgc-2022-004039. Green open access
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Caswell, Deborah R; Gui, Philippe; Mayekar, Manasi K; Law, Emily K; Pich, Oriol; Bailey, Chris; Boumelha, Jesse; ... Swanton, Charles; + view all (2023) The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance. Nature Genetics 10.1038/s41588-023-01592-8. (In press). Green open access
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Cerone, Maria Antonietta; Mills, Tara C; Sharpe, Rowena; McBride, David; MacDonald, Moira; MacMahon, Suzanne; Mugalaasi, Hood; ... SMP2, consortium; + view all (2023) The Cancer Research UK Stratified Medicine Programme as a model for delivering personalised cancer care. British Journal of Cancer 10.1038/s41416-022-02107-8. (In press). Green open access
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Chen, Kezhong; Kang, Guannan; Zhang, Zhihong; Lizaso, Analyn; Beck, Stephan; Lyskjær, Iben; Chervova, Olga; ... Wang, Jun; + view all (2023) Individualized dynamic methylation-based analysis of cell-free DNA in postoperative monitoring of lung cancer. BMC Medicine , 21 , Article 255. 10.1186/s12916-023-02954-z. Green open access
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Chi, Kim N; Rathkopf, Dana; Smith, Matthew R; Efstathiou, Eleni; Attard, Gerhardt; Olmos, David; Lee, Ji Youl; ... MAGNITUDE Principal Investigators; + view all (2023) Niraparib and Abiraterone Acetate for Metastatic Castration-Resistant Prostate Cancer. Journal of Clinical Oncology 10.1200/JCO.22.01649. (In press). Green open access
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Chi, KN; Sandhu, S; Smith, MR; Attard, G; Saad, M; Olmos, D; Castro, E; ... Efstathiou, E; + view all (2023) Niraparib plus abiraterone acetate with prednisone in patients with metastatic castration-resistant prostate cancer and homologous recombination repair gene alterations: second interim analysis of the randomized phase III MAGNITUDE trial. Annals of Oncology 10.1016/j.annonc.2023.06.009. (In press). Green open access
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Davis, LM; Elmaraghi, C; Buscombe, JR; Gaze, MN; (2023) Clinical perspectives on dosimetry in molecular radiotherapy. Physica Medica , 114 , Article 103154. 10.1016/j.ejmp.2023.103154. Green open access
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De Noon, Solange; Piggott, Robert; Trotman, Jamie; Tadross, John A; Fittall, Matthew; Hughes, Debbie; Ye, Hongtao; ... Flanagan, Adrienne M; + view all (2023) Recurrent FOSL1 rearrangements in desmoplastic fibroblastoma. The Journal of Pathology , 259 (2) pp. 119-124. 10.1002/path.6038. Green open access
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Deng, Jinhai; Pan, Teng; Liu, Zaoqu; McCarthy, Caitlin; Vicencio, Jose M; Cao, Lulu; Alfano, Giovanna; ... Ng, Tony; + view all (2023) The role of TXNIP in cancer: a fine balance between redox, metabolic, and immunological tumor control. British Journal of Cancer 10.1038/s41416-023-02442-4. (In press). Green open access
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Di Pilato, Mauro; Gao, Yun; Sun, Yi; Fu, Amina; Grass, Carina; Seeholzer, Thomas; Feederle, Regina; ... Keller, Peter; + view all (2023) Translational Studies Using the MALT1 Inhibitor (S)-Mepazine to Induce Treg Fragility and Potentiate Immune Checkpoint Therapy in Cancer. Journal of Immunotherapy and Precision Oncology , 6 (2) pp. 61-73. 10.36401/JIPO-22-18. Green open access
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Fernandez-Perez, Maria P; Perez-Navarro, Enrique; Alonso-Gordoa, Teresa; Conteduca, Vicenza; Font, Albert; Vazquez-Estevez, Sergio; Gonzalez-del-Alba, Aranzazu; ... Gonzalez-Billalabeitia, Enrique; + view all (2023) A correlative biomarker study and integrative prognostic model in chemotherapy-naive metastatic castration-resistant prostate cancer treated with enzalutamide. Prostate , 83 (4) pp. 376-384. 10.1002/pros.24469. Green open access
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Ferrer, M; Anthony, TG; Ayres, JS; Biffi, G; Brown, JC; Caan, BJ; Cespedes Feliciano, EM; ... Janowitz, T; + view all (2023) Cachexia: A systemic consequence of progressive, unresolved disease. Cell , 186 (9) pp. 1824-1845. 10.1016/j.cell.2023.03.028. Green open access
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Fittall, Matthew; Liu, Justin; Platt, James; Ionescu, Maria; Sheehan, Remarez; Johal, Sukhmunni; Mew, Rosie; ... Lee, Lennard YW; + view all (2023) The National COVID Cancer Antibody Survey: a hyper-accelerated study proof of principle for cancer research. British Journal of Cancer , 128 (11) pp. 1977-1980. 10.1038/s41416-023-02251-9. Green open access
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Floerchinger, Alessia; Klein, Jessica E; Finkbeiner, Maximiliane SC; Schaefer, Theresa E; Fuchs, Gwendolin; Doerner, Johannes; Zirngibl, Hubert; ... Engeland, Christine E; + view all (2023) A vector-encoded bispecific killer engager to harness virus-activated NK cells as anti-tumor effectors. Cell Death & Disease , 14 (2) , Article 104. 10.1038/s41419-023-05624-3. Green open access
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Frankell, AM; Dietzen, M; Al Bakir, M; Lim, EL; Karasaki, T; Ward, S; Veeriah, S; ... Gilbert, K; + view all (2023) The evolution of lung cancer and impact of subclonal selection in TRACERx. Nature , 616 pp. 525-533. 10.1038/s41586-023-05783-5. Green open access
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Galvez-Cancino, Felipe; Simpson, Alexander P; Costoya, Cristobal; Matos, Ignacio; Qian, Danwen; Peggs, Karl S; Litchfield, Kevin; (2023) Fcγ receptors and immunomodulatory antibodies in cancer. Nature Reviews Cancer , 24 (1) pp. 51-71. 10.1038/s41568-023-00637-8.

Ganguli, Sushila; Wyatt, Tom; Nyga, Agata; Lawson, Rachel H; Meyer, Tim; Baum, Buzz; Matthews, Helen K; (2023) Oncogenic Ras deregulates cell-substrate interactions during mitotic rounding and respreading to alter cell division orientation. Current Biology 10.1016/j.cub.2023.05.061. (In press). Green open access
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Gaze, MN; Smeulders, N; Ackwerh, R; Allen, C; Bal, N; Boutros, M; Cho, A; ... Hoskin, PJ; + view all (2023) A National Referral Service for Paediatric Brachytherapy: An Evolving Practice and Outcomes Over 13 Years. Clinical Oncology , 35 (4) pp. 237-244. 10.1016/j.clon.2022.12.008. Green open access
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Genoud, Vassilis; Kinnersley, Ben; Brown, Nicholas F; Ottaviani, Diego; Mulholland, Paul; (2023) Therapeutic Targeting of Glioblastoma and the Interactions with Its Microenvironment. Cancers , 15 (24) , Article 5790. 10.3390/cancers15245790. Green open access
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Gong, Grace Q; Bilanges, Benoit; Allsop, Ben; Masson, Glenn R; Roberton, Victoria; Askwith, Trevor; Oxenford, Sally; ... Vanhaesebroeck, Bart; + view all (2023) A small-molecule PI3Kα activator for cardioprotection and neuroregeneration. Nature , 618 pp. 159-168. 10.1038/s41586-023-05972-2. Green open access
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González-Martín, A; Harter, P; Leary, A; Lorusso, D; Miller, RE; Pothuri, B; Ray-Coquard, I; ... ESMO Guidelines Committee; + view all (2023) Newly diagnosed and relapsed epithelial ovarian cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up. Annals of Oncology , 34 (10) pp. 833-848. 10.1016/j.annonc.2023.07.011.

Grigoriadis, Kristiana; Huebner, Ariana; Bunkum, Abigail; Colliver, Emma; Frankell, Alexander M; Hill, Mark S; Thol, Kerstin; ... McGranahan, Nicholas; + view all (2023) CONIPHER: a computational framework for scalable phylogenetic reconstruction with error correction. Nature Protocols 10.1038/s41596-023-00913-9. (In press).

Hagos, Yeman B; Lecat, Catherine SY; Patel, Dominic; Mikolajczak, Anna; Castillo, Simon P; Lyon, Emma J; Foster, Kane; ... Yuan, Yinyin; + view all (2023) Deep learning enables spatial mapping of the mosaic microenvironment of myeloma bone marrow trephine biopsies. Cancer Research 10.1158/0008-5472.can-22-2654. Green open access
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Han, H; Yang, Y; Jiao, Y; Qi, H; Han, Z; Wang, L; Dong, L; ... Lei, H; + view all (2023) Leverage of nuclease-deficient CasX for preventing pathological angiogenesis. Molecular Therapy - Nucleic Acids , 33 pp. 738-748. 10.1016/j.omtn.2023.08.001. Green open access
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Han, Haote; Yang, Yanhui; Han, Zhuo; Wang, Luping; Dong, Lijun; Qi, Hui; Liu, Bing; ... Lei, Hetian; + view all (2023) NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial Cells. Cells , 12 (2) , Article 207. 10.3390/cells12020207. Green open access
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Hasan, AM Mahedi; Cremaschi, Paolo; Wetterskog, Daniel; Jayaram, Anuradha; Wong, Stephen Q; Williams, Scott; Pasam, Anupama; ... Attard, Gerhardt; + view all (2023) Copy number architectures define treatment-mediated selection of lethal prostate cancer clones. Nature Communications , 14 , Article 4823. 10.1038/s41467-023-40315-9. Green open access
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Hessey, Sonya; Fessas, Petros; Zaccaria, Simone; Jamal-Hanjani, Mariam; Swanton, Charles; (2023) Insights into the metastatic cascade through research autopsies. Trends Cancer 10.1016/j.trecan.2023.03.002. Green open access
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Hill, William; Lim, Emilia L.; Weeden, Clare E.; Lee, Claudia; Augustine, Marcellus; Chen, Kezhong; Kuan, Feng-Che; (2023) Lung adenocarcinoma promotion by air pollutants. Nature , 616 pp. 159-167. 10.1038/s41586-023-05874-3. Green open access
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Hol, MLF; Indelicato, DJ; Slater, O; Kolb, F; Hewitt, RJ; Ong, J; Becking, AG; ... Suttie, M; + view all (2023) Facial deformation following treatment for pediatric head and neck rhabdomyosarcoma; the difference between treatment modalities. Results of a trans-Atlantic, multicenter cross-sectional cohort study. Pediatric Blood and Cancer , 70 (8) , Article e30412. 10.1002/pbc.30412. Green open access
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Howlett, Sarah; Carter, Thomas J; Shaw, Heather M; Nathan, Paul D; (2023) Tebentafusp: a first-in-class treatment for metastatic uveal melanoma. Therapeutic Advances in Medical Oncology , 15 10.1177/17588359231160140. Green open access
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Huebner, Ariana; Black, James RM; Sarno, Francesca; Pazo, Roberto; Juez, Ignacio; Medina, Laura; Garcia-Carbonero, Rocio; ... Toledo, Rodrigo A; + view all (2023) ACT-Discover: identifying karyotype heterogeneity in pancreatic cancer evolution using ctDNA. Genome Medicine , 15 (1) , Article 27. 10.1186/s13073-023-01171-w. Green open access
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Hughes, Tessa; Dijkstra, Krijn K; Rawlins, Emma L; Hynds, Robert E; (2023) Open questions in human lung organoid research. Frontiers in Pharmacology , 13 , Article 1083017. 10.3389/fphar.2022.1083017. Green open access
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Huntley, C; Torr, B; Sud, A; Rowlands, CF; Way, R; Snape, K; Hanson, H; ... Turnbull, C; + view all (2023) Utility of polygenic risk scores in UK cancer screening: a modelling analysis. The Lancet Oncology , 24 (6) pp. 658-668. 10.1016/S1470-2045(23)00156-0. Green open access
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Jamal-Hanjani, Mariam; (2023) Body composition and lung cancer-associated cachexia in TRACERx. Nature Medicine , 29 pp. 846-858. 10.1038/s41591-023-02232-8. Green open access
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Jamal-Hanjani, Mariam; (2023) High resolution phylogenetic ctDNA tracking predicts relapse risk and metastatic dissemination patterns in early-stage lung cancer. Nature (In press).

Karasaki, T; Moore, DA; Veeriah, S; Naceur-Lombardelli, C; Toncheva, A; Magno, N; Ward, S; ... Jamal-Hanjani, M; + view all (2023) Evolutionary characterization of lung adenocarcinoma morphology in TRACERx. Nature Medicine , 29 pp. 833-845. 10.1038/s41591-023-02230-w. Green open access
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Karasaki, Takahiro; Moore, David A; Jamal-Hanjani, Mariam; (2023) Clinicogenomic landscape of morphological evolution in lung adenocarcinoma. Nature Medicine , 29 (4) pp. 795-796. 10.1038/s41591-023-02231-9. Green open access
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Kelly, SM; Turcas, A; Corning, C; Bailey, S; Cañete, A; Clementel, E; di Cataldo, A; ... Mandeville, H; + view all (2023) Radiotherapy quality assurance in paediatric clinical trials: first report from six QUARTET-affiliated trials. Radiotherapy and Oncology , 182 , Article 109549. 10.1016/j.radonc.2023.109549. Green open access
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Keshwani, K; Boterberg, T; Dieckmann, K; Janssens, GO; Laprie, A; Timmermann, B; Gaze, MN; (2023) Radical skeletal metastatic site irradiation in highrisk neuroblastoma: systematic review and proposal for a randomised trial: a report from the SIOPEN Radiotherapy Committee. Journal of Cancer Metastasis and Treatment , 9 (1) 10.20517/2394-4722.2022.32. Green open access
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Kobialka, Piotr; Llena, Judith; Deleyto-Seldas, Nerea; Munar-Gelabert, MARGALIDA; Dengra, JOSE A; Villacampa, ALBA; Albinyà-Pedrós, Alba; ... Graupera, Mariona; + view all (2023) PI3K-C2β limits mTORC1 signaling and angiogenic growth. Science Signaling , 16 (813) , Article eadg19. 10.1126/scisignal.adg1913. Green open access
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Kudo, Masatoshi; Finn, Richard S; Ikeda, Masafumi; Sung, Max W; Baron, Ari D; Okusaka, Takuji; Kobayashi, Masahiro; ... Llovet, Josep M; + view all (2023) A Phase 1b Study of Lenvatinib plus Pembrolizumab in Patients with Unresectable Hepatocellular Carcinoma: Extended Analysis of Study 116. Liver Cancer 10.1159/000535154. (In press). Green open access
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Ledermann, JA; Shapira-Frommer, R; Santin, AD; Lisyanskaya, AS; Pignata, S; Vergote, I; Raspagliesi, F; ... Matulonis, UA; + view all (2023) Molecular determinants of clinical outcomes of pembrolizumab in recurrent ovarian cancer: Exploratory analysis of KEYNOTE-100. Gynecologic Oncology , 178 pp. 119-129. 10.1016/j.ygyno.2023.09.012.

Li, Y; Jiang, G; Wu, W; Yang, H; Jin, Y; Wu, M; Liu, W; ... Chen, K; + view all (2023) Multi-omics integrated circulating cell-free DNA genomic signatures enhanced the diagnostic performance of early-stage lung cancer and postoperative minimal residual disease. eBioMedicine , 91 , Article 104553. 10.1016/j.ebiom.2023.104553. Green open access
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Liebert, Casril; Morka, Naomi; Satish, Pranav; Freeman, Alex; Kelly, Daniel; Kirkham, Alex; Orczyk, Clement; ... Norris, Joseph M; + view all (2023) Diagnostic potential of radiological apical tumor involvement. Journal of Robotic Surgery , 17 pp. 705-706. 10.1007/s11701-022-01413-w. Green open access
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Llovet, JM; Kudo, M; Merle, P; Meyer, T; Qin, S; Ikeda, M; Xu, R; ... Finn, RS; + view all (2023) Lenvatinib plus pembrolizumab versus lenvatinib plus placebo for advanced hepatocellular carcinoma (LEAP-002): a randomised, double-blind, phase 3 trial. The Lancet Oncology , 24 (12) pp. 1399-1410. 10.1016/S1470-2045(23)00469-2.

Martínez-Ruiz, C; Black, JRM; Puttick, C; Hill, MS; Demeulemeester, J; Larose Cadieux, E; Thol, K; ... McGranahan, N; + view all (2023) Genomic–transcriptomic evolution in lung cancer and metastasis. Nature , 616 pp. 543-552. 10.1038/s41586-023-05706-4. Green open access
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Masoud, AG; Lin, J; Zhu, LF; Tao, K; Ness, NW; Kassiri, Z; Moore, RB; ... Murray, AG; + view all (2023) Endothelial phosphoinositide 3-kinase-β inactivation confers protection from immune-mediated vascular injury. American Journal of Transplantation , 23 (2) pp. 202-213. 10.1016/j.ajt.2022.11.014. Green open access
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Massana-Muñoz, Xènia; Goret, Marie; Nattarayan, Vasugi; Reiss, David; Kretz, Christine; Chicanne, Gaetan; Payrastre, Bernard; ... Laporte, Jocelyn; + view all (2023) Inactivating the lipid kinase activity of PI3KC2β is sufficient to rescue myotubular myopathy in mice. JCI Insight , 8 (9) , Article e151933. 10.1172/jci.insight.151933. Green open access
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McDonald, James; Sayers, Judith; Anker, Stefan D; Arends, Jann; Balstad, Trude; Baracos, Vickie; Brown, Leo; ... Cancer Cachexia Endpoints Working, Group; + view all (2023) Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle 10.1002/jcsm.13321. (In press). Green open access
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Meyer, Tim; Galani, Sevasti; Lopes, Andre; Vogel, Arndt; (2023) Aetiology of liver disease and response to immune checkpoint inhibitors: an updated meta-analysis confirms benefit in those with non-viral liver disease. Journal of Hepatology , 79 (2) e73-e76. 10.1016/j.jhep.2023.04.012.

Moore, KN; Angelergues, A; Konecny, GE; García, Y; Banerjee, S; Lorusso, D; Lee, JY; ... Van Gorp, T; + view all (2023) Mirvetuximab Soravtansine in FRα-Positive, Platinum-Resistant Ovarian Cancer. New England Journal of Medicine , 389 (23) pp. 2162-2174. 10.1056/NEJMoa2309169.

Morgan, Robert D; Clamp, Andrew R; Barnes, Bethany M; Timms, Kirsten; Schlecht, Helene; Yarram-Smith, Laura; Wallis, Yvonne; ... Jayson, Gordon C; + view all (2023) Homologous recombination deficiency in newly diagnosed FIGO stage III/IV high-grade epithelial ovarian cancer: a multi-national observational study. International Journal of Gynecological Cancer 10.1136/ijgc-2022-004211. (In press). Green open access
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Muñoz-Ruiz, Miguel; Llorian, Miriam; D'Antuono, Rocco; Pavlova, Anna; Mavrigiannaki, Anna Maria; McKenzie, Duncan; García-Cassani, Bethania; ... Hayday, Adrian C; + view all (2023) Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis. Journal of Allergy and Clinical Immunology 10.1016/j.jaci.2023.07.015. (In press). Green open access
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Ng, Kenrick; Metcalf, Rob; Sacco, Joseph; Kong, Anthony; Wheeler, Graham; Forsyth, Sharon; Bhat, Reshma; ... Forster, Martin; + view all (2023) Protocol for the EACH trial: a multicentre phase II study evaluating the safety and antitumour activity of the combination of avelumab, an anti-PD-L1 agent, and cetuximab, as any line treatment for patients with recurrent/metastatic head and neck squamous cell cancer (HNSCC) in the UK. BMJ Open , 13 (11) , Article e070391. 10.1136/bmjopen-2022-070391. Green open access
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Ng, Kevin W; Boumelha, Jesse; Enfield, Katey SS; Almagro, Jorge; Cha, Hongui; Pich, Oriol; Karasaki, Takahiro; ... Kassiotis, George; + view all (2023) Antibodies against endogenous retroviruses promote lung cancer immunotherapy. Nature 10.1038/s41586-023-05771-9. (In press). Green open access
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Nuttall Musson, Ellen; Miller, Rowan E; Mansour, Marc R; Lockley, Michelle; Ledermann, Jonathan A; Payne, Elspeth M; (2023) Monitoring clone dynamics and reversibility in clonal haematopoiesis and myelodysplastic neoplasm associated with PARP inhibitor therapy-a role for early monitoring and intervention. Leukemia 10.1038/s41375-023-02040-6. (In press). Green open access
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Oxley, Samuel; Kalra, Ashwin; Sideris, Michail; Itzkowitz, Nicole; Evans, Olivia; Atakpa, Emma Christine; Brentnall, Adam R; ... Manchanda, Ranjit; + view all (2023) Impact of Multiple COVID-19 Waves on Gynaecological Cancer Services in the UK. Cancers , 15 (4) , Article 1273. 10.3390/cancers15041273. Green open access
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Pearce, David RR; Akarca, Ayse UU; De Maeyer, Roel PH; Kostina, Emily; Huebner, Ariana; Sivakumar, Monica; Karasaki, Takahiro; ... Hynds, Robert EE; + view all (2023) Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer. Frontiers in Oncology , 13 , Article 1156743. 10.3389/fonc.2023.1156743. Green open access
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Peipert, John Devin; Goble, Sandra; Isaacson, Jeff; Tang, Xiaodan; Wallace, Katrine; Coleman, Robert L; Ledermann, Jonathan A; (2023) Patient-reported outcomes of maintenance rucaparib in patients with recurrent ovarian carcinoma in ARIEL3, a phase III, randomized, placebo-controlled trial. Gynecologic Oncology , 175 pp. 1-7. 10.1016/j.ygyno.2023.05060.

Pinder, Christopher L; Jankovic, Dylan; Fox, Thomas A; Kirkwood, Amy; Enfield, Louise; Alrubayyi, Aljawharah; Touizer, Emma; ... Morris, Emma C; + view all (2023) Humoral and cellular responses to SARS-CoV-2 in patients with B-cell haematological malignancies improve with successive vaccination. British Journal of Haematology 10.1111/bjh.18962. (In press). Green open access
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Propper, David J; Gao, Fangfei; Saunders, Mark P; Sarker, Debashis; Hartley, John A; Spanswick, Victoria J; Lowe, Helen L; ... Hochhauser, Daniel; + view all (2023) PANTHER: AZD8931, inhibitor of EGFR, ERBB2 and ERBB3 signalling, combined with FOLFIRI: a Phase I/II study to determine the importance of schedule and activity in colorectal cancer. British Journal of Cancer , 128 (2) pp. 245-254. 10.1038/s41416-022-02015-x. Green open access
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Pruis, Melinda A; Krebs, Matthew G; Plummer, Ruth; De Vos, Filip; Angevin, Eric; Prenen, Hans; Forster, Martin D; ... Lolkema, Martijn P; + view all (2023) A Phase I Trial of the Dual MET Kinase/OCT-2 Inhibitor OMO-1 in Metastatic Solid Malignancies Including MET Exon 14 Mutated Lung Cancer. The Oncologist , Article oyad146. 10.1093/oncolo/oyad146. (In press). Green open access
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Purro, Silvia A; Farmer, Michael; Noble, Elizabeth; Sarell, Claire J; Powell, Megan; Yip, Daniel; Giggins, Lauren; ... Collinge, John; + view all (2023) Two mouse models of Alzheimer's disease accumulate amyloid at different rates and have distinct Aβ oligomer profiles unaltered by ablation of cellular prion protein. PLoS One , 18 (11) , Article e0294465. 10.1371/journal.pone.0294465. Green open access
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Qin, Shukui; Kudo, Masatoshi; Meyer, Tim; Bai, Yuxian; Guo, Yabing; Meng, Zhiqiang; Satoh, Taroh; ... Zhu, Andrew X; + view all (2023) Tislelizumab vs Sorafenib as First-Line Treatment for Unresectable Hepatocellular Carcinoma: A Phase 3 Randomized Clinical Trial. JAMA Oncology 10.1001/jamaoncol.2023.4003. (In press). Green open access
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Qin, Xiao; Cardoso Rodriguez, Ferran; Sufi, Jahangir; Vlckova, Petra; Claus, Jeroen; Tape, Christopher J; (2023) An oncogenic phenoscape of colonic stem cell polarization. Cell , 186 (25) 5554-5568.e18. 10.1016/j.cell.2023.11.004. Green open access
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Rajan, Sanjana; Zaccaria, Simone; Cannon, Matthew V; Cam, Maren; Gross, Amy C; Raphael, Benjamin J; Roberts, Ryan D; (2023) Structurally Complex Osteosarcoma Genomes Exhibit Limited Heterogeneity within Individual Tumors and across Evolutionary Time. Cancer Research Communications , 3 (4) pp. 564-575. 10.1158/2767-9764.CRC-22-0348. Green open access
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Ramos Zapatero, María; Tong, Alexander; Opzoomer, James W; O’Sullivan, Rhianna; Cardoso Rodriguez, Ferran; Sufi, Jahangir; Vlckova, Petra; ... Tape, Christopher J; + view all (2023) Trellis tree-based analysis reveals stromal regulation of patient-derived organoid drug responses. Cell , 186 (25) 5606-5619.e24. 10.1016/j.cell.2023.11.005. Green open access
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Rane, Jayant K; Frankell, Alexander M; Weeden, Clare E; Swanton, Charles; (2023) Clonal Evolution in Healthy and Premalignant Tissues: Implications for Early Cancer Interception Strategies. Cancer Prevention Research , 16 (7) pp. 369-378. 10.1158/1940-6207.CAPR-22-0469. Green open access
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Reading, James L; Caswell, Deborah R; Swanton, Charles; (2023) Tumor heterogeneity impairs immunogenicity in mismatch repair deficient tumors. Nature Genetics , 55 (10) pp. 1610-1612. 10.1038/s41588-023-01492-x. Green open access
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Sacher, Adrian; LoRusso, Patricia; Patel, Manish R; Miller, Wilson H; Garralda, Elena; Forster, Martin D; Santoro, Armando; ... GO42144 Investigator and Study Group; + view all (2023) Single-Agent Divarasib (GDC-6036) in Solid Tumors with a KRAS G12C Mutation. New England Journal of Medicine , 389 (8) pp. 710-721. 10.1056/NEJMoa2303810. Green open access
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Sasieni, P; Smittenaar, R; Hubbell, E; Broggio, J; Neal, RD; Swanton, C; (2023) Modelled mortality benefits of multi-cancer early detection screening in England. British Journal of Cancer , 129 pp. 72-80. 10.1038/s41416-023-02243-9. Green open access
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Sessa, C; Balmaña, J; Bober, SL; Cardoso, MJ; Colombo, N; Curigliano, G; Domchek, SM; ... ESMO, Guidelines Committee; + view all (2023) Risk reduction and screening of cancer in hereditary breast-ovarian cancer syndromes: ESMO Clinical Practice Guideline. Annals of Oncology , 34 (1) pp. 33-47. 10.1016/j.annonc.2022.10.004. Green open access
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Shovlin, CL; Patel, D; Bielowka, A; Ledermann, JA; Modarresi, A; Bernabeu-Herrero, ME; Aldred, MA; (2023) MEK 1 inhibition and bleeding in hereditary haemorrhagic telangiectasia. British Journal of Haematology 10.1111/bjh.19167. (In press). Green open access
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Silveira, Maria Jose; Martins, Claudia; Cruz, Tania; Castro, Flavia; Amorim-Costa, Angela; Chester, Kerry; Oliveira, Maria Jose; (2023) scFv biofunctionalized nanoparticles to effective and safe targeting of CEA-expressing colorectal cancer cells. Journal of Nanobiotechnology , 21 (1) , Article 357. 10.1186/s12951-023-02126-4. Green open access
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Spain, Lavinia; Coulton, Alexander; Lobon, Irene; Rowan, Andrew; Schnidrig, Desiree; Shepherd, Scott TC; Shum, Benjamin; ... Turajlic, Samra; + view all (2023) Late-Stage Metastatic Melanoma Emerges through a Diversity of Evolutionary Pathways. Cancer Discovery , 13 (6) pp. 1364-1385. 10.1158/2159-8290.CD-22-1427. Green open access
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Starkey, Thomas; Ionescu, Maria; Tilby, Michael; Little, Martin W; Burke, Emma; Fittall, Matthew; Khan, Sam R; ... NCRI, Consumer Forum; + view all (2023) A population-scale temporal case-control evaluation of COVID-19 disease phenotype and related outcome rates in patients with cancer in England (UKCCP). Scientific Reports , 13 (1) , Article 11327. 10.1038/s41598-023-36990-9. Green open access
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Stavrinides, Vasilis; Eksi, Ece; Finn, Ron; Texeira-Mendes, Larissa; Rana, Sarina; Trahearn, Nick; Grey, Alistair; ... Orczyk, Clement; + view all (2023) Magnetic Resonance Imaging Follow-up of Targeted Biopsy-negative Prostate Lesions. European Urology Focus 10.1016/j.euf.2023.03.011. (In press). Green open access
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Stavrinides, Vasilis; Norris, Joseph M; Karapanagiotis, Solon; Giganti, Francesco; Grey, Alistair; Trahearn, Nick; Freeman, Alex; ... PROMIS Group; + view all (2023) Regional Histopathology and Prostate MRI Positivity: A Secondary Analysis of the PROMIS Trial. Radiology , 307 (1) , Article 220762. 10.1148/radiol.220762. Green open access
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Strauss, Sandra; (2023) Incidence and survival of soft tissue sarcoma in England between 2013-2017, an analysis from the National Cancer Registration and Analysis Service. International Journal of Cancer , 152 (9) pp. 1789-1803. 10.1002/ijc.34409. Green open access
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Sundar, Sudha; Nordin, Andy; Morrison, Jo; Wood, Nick; Ghaem-Maghami, Sadaf; Nieto, Jo; Phillips, Andrew; ... Fotopoulou, Christina; + view all (2023) British Gynaecological Cancer Society Recommendations for Evidence Based, Population Data Derived Quality Performance Indicators for Ovarian Cancer. Cancers , 15 (2) , Article 337. 10.3390/cancers15020337. Green open access
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Tang, WHW; Yimer, H; Tummala, M; Shao, S; Chung, G; Clement, J; Chu, BC; ... Roberts, LR; + view all (2023) Performance of a targeted methylation-based multi-cancer early detection test by race and ethnicity. Preventive Medicine , 167 , Article 107384. 10.1016/j.ypmed.2022.107384. Green open access
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Taniere, Phillipe; Nicholson, Andrew G; Gosney, John R; Montero Fernandez, Maria Angeles; Bury, Danielle; Moore, David Allan; Verghese, Eldo; ... Ryan, Jacqueline; + view all (2023) Landscape of cancer biomarker testing in England following genomic services reconfiguration: insights from a nationwide pathologist survey. Journal of Clinical Pathology 10.1136/jcp-2023-208890. (In press). Green open access
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Tape, Christopher J; (2023) Plastic persisters: revival stem cells in colorectal cancer. Trends in Cancer 10.1016/j.trecan.2023.11.003. (In press). Green open access
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Thagaard, J; Broeckx, G; Page, DB; Jahangir, CA; Verbandt, S; Kos, Z; Gupta, R; ... Reis-Filho, JS; + view all (2023) Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: a report of the international immuno-oncology biomarker working group. Journal of Pathology , 260 (5) pp. 498-513. 10.1002/path.6155. Green open access
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Thomas, Maya; Murali, Sanjana; Simpson, Benjamin Scott S; Freeman, Alex; Kirkham, Alex; Kelly, Daniel; Whitaker, Hayley C; ... Norris, Joseph M; + view all (2023) Use of artificial intelligence in the detection of primary prostate cancer in multiparametric MRI with its clinical outcomes: a protocol for a systematic review and meta-analysis. BMJ Open , 13 (8) , Article e074009. 10.1136/bmjopen-2023-074009. Green open access
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Tirotta, Fabio; Bacon, Andrew; Collins, Shane; Desai, Anant; Liu, Hanhua; Paley, Lizz; Strauss, Dirk; (2023) Primary retroperitoneal sarcoma: A comparison of survival outcomes in specialist and non-specialist sarcoma centres. European Journal of Cancer , 188 pp. 20-28. 10.1016/j.ejca.2023.04.004. Green open access
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Tommasini, Fabio; Benoist, Thomas; Shibuya, Soichi; Woodall, Maximillian NJ; Naldi, Eleonora; Palor, Machaela; Orr, Jessica C; ... De Coppi, Paolo; + view all (2023) Lung viral infection modelling in a bioengineered whole-organ. Biomaterials , 301 , Article 122203. 10.1016/j.biomaterials.2023.122203.

Turcas, A; Kelly, SM; Bernier-Chastagner, V; Bolle, S; Cameron, A; Corning, C; Clementel, E; ... Mandeville, HC; + view all (2023) Management of the vertebrae as an organ at risk in paediatric radiotherapy clinical trials: Initial QUARTET experience. Radiotherapy and Oncology , 187 , Article 109810. 10.1016/j.radonc.2023.109810. Green open access
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Usaite, Ieva; Biswas, Dhruva; Dijkstra, Krijn; Watkins, Thomas Bk; Pich, Oriol; Puttick, Clare; Angelova, Mihaela; ... Kanu, Nnennaya; + view all (2023) Quantifying the impact of immunotherapy on RNA dynamics in cancer. Journal for ImmunoTherapy of Cancer , 11 (11) , Article e007870. 10.1136/jitc-2023-007870. Green open access
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van Ewijk, Roelof; Cleirec, Morgane; Herold, Nikolas; le Deley, Marie-Cécile; van Eijkelenburg, Natasha; Boudou-Rouquette, Pascaline; Risbourg, Séverine; ... FOSTER Consortium, .; + view all (2023) A systematic review of recent phase-II trials in refractory or recurrent osteosarcoma: Can we inform future trial design? Cancer Treatment Reviews , 120 , Article 102625. 10.1016/j.ctrv.2023.102625. (In press). Green open access
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Velikova, Galina; Morden, James P; Haviland, Joanne S; Emery, Charlotte; Barrett-Lee, Peter; Earl, Helena; Bloomfield, David; ... Cameron, David; + view all (2023) Accelerated versus standard epirubicin followed by cyclophosphamide, methotrexate, and fluorouracil or capecitabine as adjuvant therapy for breast cancer (UK TACT2; CRUK/05/19): quality of life results from a multicentre, phase 3, open-label, randomised, controlled trial. The Lancet Oncology 10.1016/s1470-2045(23)00460-6. (In press). Green open access
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Vogel, Arndt; Grant, Robert C; Meyer, Tim; Sapisochin, Gonzalo; O'Kane, Grainne M; Saborowski, Anna; (2023) Adjuvant and neoadjuvant therapies for hepatocellular carcinoma. Hepatology 10.1097/HEP.0000000000000726. (In press).

Vogel, Arndt; Kelley, Robin Kate; Johnson, Philip; Merle, Philippe; Yau, Thomas; Kudo, Masatoshi; Meyer, Tim; (2023) Predictive and prognostic potential of liver function assessment in patients with advanced hepatocellular carcinoma: a systematic literature review. Liver Cancer , 12 (4) pp. 372-391. 10.1159/000529173. Green open access
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Watkins, Thomas BK; Colliver, Emma C; Huska, Matthew R; Kaufmann, Tom L; Lim, Emilia L; Duncan, Cody B; Haase, Kerstin; ... Schwarz, Roland F; + view all (2023) Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity. PLoS Computational Biology , 19 (10) , Article e1011379. 10.1371/journal.pcbi.1011379. Green open access
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Weeden, CE; Gayevskiy, V; Marceaux, C; Batey, D; Tan, T; Yokote, K; Ribera, NT; ... Asselin-Labat, ML; + view all (2023) Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer. Cancer Cell , 41 (5) 837-852.e6. 10.1016/j.ccell.2023.03.019. Green open access
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Weiner, Adam BB; Liu, Yang; Hakansson, Alex; Zhao, Xin; Proudfoot, James AA; Ho, Julian; Zhang, JJHH; ... Schaeffer, Edward MM; + view all (2023) A novel prostate cancer subtyping classifier based on luminal and basal phenotypes. Cancers 10.1002/cncr.34790. (In press). Green open access
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Woll, Penella J; Gaunt, Piers; Gaskell, Charlotte; Young, Robin; Benson, Charlotte; Judson, Ian R; Seddon, Beatrice M; ... Billingham, Lucinda; + view all (2023) Axitinib in patients with advanced/metastatic soft tissue sarcoma (Axi-STS): an open-label, multicentre, phase II trial in four histological strata. British Journal of Cancer (BJC) 10.1038/s41416-023-02416-6. (In press). Green open access
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Wood, Georgina E; Graves, Laurie A; Rubin, Elyssa M; Reed, Damon R; Riedel, Richard F; Strauss, Sandra J; (2023) Bad to the Bone: Emerging Approaches to Aggressive Bone Sarcomas. American Society of Clinical Oncology Educational Book , 43 (43) , Article e390306. 10.1200/EDBK_390306.

Wu, MY; Shepherd, STC; Fendler, A; Carr, EJ; Au, L; Harvey, R; Dowgier, G; ... Turajlic, S; + view all (2023) Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer. Cancer Cell , 41 (5) pp. 821-823. 10.1016/j.ccell.2023.04.005. Green open access
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Wu, Wenyi; Ma, Gaoen; Qi, Hui; Dong, Lijun; Chen, Fang; Wang, Yun; Mao, Xingxing; ... Lei, Hetian; + view all (2023) Correction to: Genome Editing of Pik3cd Impedes Abnormal Retinal Angiogenesis, by Wu et al. Hum Gene Ther 2023;34(1-2):30-41; doi: 10.1089/hum.2022.079. [Corrigendum]. Human Gene Therapy , 34 (9-10) p. 471. 10.1089/hum.2022.079.correx. Green open access
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Zhang, H; AbdulJabbar, K; Grunewald, T; Akarca, AU; Hagos, Y; Sobhani, F; Lecat, CSY; ... Yuan, Y; + view all (2023) Self-supervised deep learning for highly efficient spatial immunophenotyping. eBioMedicine , 95 , Article 104769. 10.1016/j.ebiom.2023.104769. Green open access
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Zhang, Hanyun; AbdulJabbar, Khalid; Moore, David A; Akarca, Ayse; Enfield, Katey SS; Jamal-Hanjani, Mariam; Raza, Shan E Ahmed; ... Yuan, Yinyin; + view all (2023) Spatial Positioning of Immune Hotspots Reflects the Interplay between B and T Cells in Lung Squamous Cell Carcinoma. Cancer Research , 83 (9) pp. 1410-1425. 10.1158/0008-5472.CAN-22-2589. Green open access
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Ziff, Oliver J; Neeves, Jacob; Mitchell, Jamie; Tyzack, Giulia; Martinez-Ruiz, Carlos; Luisier, Raphaelle; Chakrabarti, Anob M; ... Patani, Rickie; + view all (2023) Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology. Nature Communications , 14 , Article 2176. 10.1038/s41467-023-37630-6. Green open access
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Proceedings paper

Yi, W; Stavrinides, V; Baum, ZMC; Yang, Q; Barratt, DC; Clarkson, MJ; Hu, Y; (2023) Boundary-RL: Reinforcement Learning for Weakly-Supervised Prostate Segmentation in TRUS Images. In: Cao, Xiaohuan and Xu, Xuanang and Rekik, Islem and Cui, Zhiming and Ouyang, Xi, (eds.) Machine Learning in Medical Imaging. (pp. pp. 277-288). Springer Nature: Cham, Switzerland. Green open access
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Thesis

Tran, Hoang Son; (2023) Integrating multi-omics data by mapping subclonal events on tumour evolutionary trees. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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This list was generated on Wed May 8 17:07:25 2024 BST.