UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Management of the vertebrae as an organ at risk in paediatric radiotherapy clinical trials: Initial QUARTET experience

Turcas, A; Kelly, SM; Bernier-Chastagner, V; Bolle, S; Cameron, A; Corning, C; Clementel, E; ... Mandeville, HC; + view all (2023) Management of the vertebrae as an organ at risk in paediatric radiotherapy clinical trials: Initial QUARTET experience. Radiotherapy and Oncology , 187 , Article 109810. 10.1016/j.radonc.2023.109810. Green open access

[thumbnail of PIIS0167814023003675.pdf]
Preview
Text
PIIS0167814023003675.pdf - Other

Download (1MB) | Preview

Abstract

Irradiation of the vertebrae in prepubertal patients, if non-homogenous, can result in future growth deformities including kyphoscoliosis. Vertebral delineation and dosimetry were assessed for 101 paediatric cases reviewed within QUARTET-affiliated trials. Despite the availability of published consensus guidelines, a high variability in vertebral delineation was observed, with impact on dosimetry.

Type: Article
Title: Management of the vertebrae as an organ at risk in paediatric radiotherapy clinical trials: Initial QUARTET experience
Location: Ireland
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.radonc.2023.109810
Publisher version: https://doi.org/10.1016/j.radonc.2023.109810
Language: English
Additional information: © 2023 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Keywords: Radiotherapy, Pediatrics, Clinical trial, Quality assurance, Vertebrae
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Oncology
URI: https://discovery.ucl.ac.uk/id/eprint/10182201
Downloads since deposit
4Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item