Browse by UCL Departments and Centres
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Number of items: 107.
A
Agbebi, TV;
(2019)
Design and characterization of a miniature photobioreactor for microalgae culture.
Masters thesis (M.Phil), UCL (University College London).
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Albay, A;
Artim-Esen, B;
Pericleous, C;
Wincup, C;
Giles, I;
Rahman, A;
McDonnell, T;
(2019)
Domain I of β2GPI is capable of blocking serum IgA antiphospholipid antibodies binding in vitro: an effect enhanced by PEGylation.
Lupus
10.1177/0961203319851571.
(In press).
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Ali, Sadfer;
(2019)
Synthetic Biology Approaches to Lentiviral Packaging Cell Engineering.
Doctoral thesis (Eng.D), UCL (University College London).
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Ali, J;
Rafiq, Q;
Ratcliffe, E;
(2019)
A scaled down model for the translation of bacteriophage culture to manufacturing scale.
Biotechnology and Bioengineering
, 116
(5)
pp. 972-984.
10.1002/bit.26911.
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Ammoury, C;
Younes, M;
El Khoury, M;
Hodroj, MH;
Haykal, T;
Nasr, P;
Sily, M;
... Rizk, S; + view all
(2019)
The pro-apoptotic effect of a Terpene-rich Annona cherimola leaf extract on leukemic cell lines.
BMC Complementary and Alternative Medicine
, 19
(1)
, Article 365. 10.1186/s12906-019-2768-1.
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Antoniou, A;
Lenart, I;
Kriston-Vizi, J;
Takao, I;
Turmaine, M;
McHugh, K;
Ali, S;
... Powis, S; + view all
(2019)
Salmonella exploits HLA-B27 and host Unfolded Protein Responses to promote intracellular replication.
Annals of the Rheumatic Diseases
, 78
(1)
pp. 74-82.
10.1136/ annrheumdis-2018-213532.
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Arnott, PM;
Howorka, S;
(2019)
A Temperature-Gated Nanovalve Self-Assembled from DNA to Control Molecular Transport across Membranes.
ACS Nano
, 13
(3)
pp. 3334-3340.
10.1021/acsnano.8b09200.
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Asra, Aisha Mariam;
(2019)
Novel chassis for engineered pathways and automating biological experiments in the biotechnology industry.
Doctoral thesis (Eng.D), UCL (University College London).
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B
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Bains, S;
(2019)
Teaching Technical Communication to Engineering Students at Scale.
In:
2019 IEEE International Professional Communication Conference (ProComm).
(pp. pp. 83-89).
IEEE: Aachen, Germany, Germany.
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Bains, S;
(2019)
Workshop: Making a Technical Argument –Teaching Technical Analysis and Communication Together.
In:
2019 IEEE International Professional Communication Conference (ProComm).
(pp. pp. 273-274).
IEEE: Aachen, Germany, Germany.
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Bajić, Marijan;
Ročnik, Tina;
Oberlintner, Ana;
Scognamiglio, Francesca;
Novak, Uroš;
Likozar, Blaž;
(2019)
Natural plant extracts as active components in chitosan-based films: A comparative study.
Food Packaging and Shelf Life
, 21
, Article 100365. 10.1016/j.fpsl.2019.100365.
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Bajić, M;
Novak, U;
Likozar, B;
(2019)
Development of bio-based chitosan films with incorporated chestnut extract.
In:
Proceedings of the 5th World Congress on Mechanical, Chemical, and Material Engineering (MCM'19).
Avestia Publishing: Lisbon, Portugal.
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Bandyopadhyay, Sushobhan Kalyankumar;
(2019)
Addressing lipid impurities in Pichia pastoris cells producing virus like particles: genetic and bioprocess studies.
Doctoral thesis (Ph.D), UCL (University College London).
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Braun-Galleani, S;
Henríquez, M-J;
Nesbeth, D;
(2019)
Whole cell biosynthesis of 1-methyl-3-phenylpropylamine and 2-amino-1,3,4-butanetriol using Komagataella phaffii (Pichia pastoris) strain BG-10 engineered with a transgene encoding Chromobacterium violaceum ω- transaminase.
Heliyon
, 5
(8)
, Article e02338. 10.1016/j.heliyon.2019.e02338.
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C
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Codina, N;
Zhang, C;
Chakroun, N;
Dalby, PA;
(2019)
Insights into the stability of a therapeutic antibody Fab fragment by molecular dynamics and its stabilization by computational design.
BioRxiv: Cold Spring Harbor, NY, USA.
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Codina, N;
Hilton, D;
Zhang, C;
Chakroun, N;
Ahmad, SS;
Perkins, SJ;
Dalby, PA;
(2019)
An Expanded Conformation of an Antibody Fab Region by X-Ray Scattering, Molecular Dynamics and smFRET Identifies an Aggregation Mechanism.
Journal of Molecular Biology
10.1016/j.jmb.2019.02.009.
(In press).
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Costariol, E;
Rotondi, M;
Amini, A;
Hewitt, CJ;
Nienow, AW;
Heathman, TRJ;
Micheletti, M;
(2019)
Establishing the scalable manufacture of primary human T-cells in an automated stirred-tank bioreactor.
Biotechnology and Bioengineering
, 116
(10)
pp. 2488-2510.
10.1002/bit.27088.
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D
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De Silva Thompson, D;
Peticone, C;
Burova, I;
Shipley, RJ;
Knowles, JC;
Kim, H-W;
Micheletti, M;
(2019)
Assessing behaviour of osteoblastic cells in dynamic culture conditions using titanium-doped phosphate glass microcarriers.
Journal of Tissue Engineering
, 10
pp. 1-13.
10.1177/2041731419825772.
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Deng, J;
Wang, X;
Zhang, B-Z;
Gao, P;
Lin, Q;
Kao, RY-T;
Gustafsson, K;
... Huang, J-D; + view all
(2019)
Broad and Effective Protection against Staphylococcus aureus Is Elicited by a Multivalent Vaccine Formulated with Novel Antigens.
mSphere
, 4
, Article e00362-19. 10.1128/mSphere.00362-19.
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Dikicioglu, D;
Oliver, SG;
(2019)
Extension of the yeast metabolic model to include iron metabolism and its use to estimate global levels of iron-recruiting enzyme abundance from cofactor requirements.
Biotechnology and Bioengineering
, 116
(3)
pp. 610-621.
10.1002/bit.26905.
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Dobrijevic, D;
Benhamou, L;
Aliev, AE;
Méndez-Sánchez, D;
Dawson, N;
Baud, D;
Tappertzhofen, N;
... Ward, JM; + view all
(2019)
Metagenomic ene-reductases for the bioreduction of sterically challenging enones.
RSC Advances
, 9
(63)
pp. 36608-36614.
10.1039/c9ra06088j.
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Dorward, A;
O'Kennedy, RD;
Folarin, O;
Ward, JM;
Keshavarz-Moore, E;
(2019)
The role of amino acids in the amplification and quality of DNA vectors for industrial applications.
Biotechnology Progress
, 35
(6)
, Article e2883. 10.1002/btpr.2883.
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E
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Edelblum, K;
Gustafsson, K;
Pennington, DJ;
Willcox, BE;
Ribot, JC;
(2019)
Bordeaux 2018: Wine, Cheese, and γδ T Cells.
Frontiers in Immunology
, 10
, Article 2544. 10.3389/fimmu.2019.02544.
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F
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Farid, SS;
(2019)
Integrated Continuous Biomanufacturing: Industrialization on the Horizon.
Biotechnology Journal
, 14
(2)
, Article 1800722. 10.1002/biot.201800722.
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Fernandez-Cerezo, L;
Rayat, ACME;
Chatel, A;
Pollard, JM;
Lye, GJ;
Hoare, M;
(2019)
An ultra scale-down method to investigate monoclonal antibody processing during tangential flow filtration (TFF) using ultrafiltration membranes.
Biotechnology and Bioengineering
, 116
pp. 581-590.
10.1002/bit.26859.
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Fischer, V;
Kucia-Tran, R;
Lewis, W;
Velayudhan, A;
(2019)
Hybrid optimization of preparative chromatography for a ternary monoclonal antibody mixture.
Biotechnology Progress
, 35
(5)
, Article e2849. 10.1002/btpr.2849.
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Flores-Fernández, CN;
Cárdenas-Fernández, M;
Dobrijevic, D;
Jurlewicz, K;
Zavaleta, AI;
Ward, JM;
Lye, GJ;
(2019)
Novel extremophilic proteases from Pseudomonas aeruginosa M211 and their application in the hydrolysis of dried distiller's grain with solubles.
Biotechnology Progress
, 35
(1)
, Article e2728. 10.1002/btpr.2728.
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Folarin, O;
Nesbeth, D;
Ward, JM;
Keshavarz-Moore, E;
(2019)
Application of Plasmid Engineering to Enhance Yield and Quality of Plasmid for Vaccine and Gene Therapy.
Bioengineering
, 6
(2)
, Article 54. 10.3390/bioengineering6020054.
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G
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Gangadharan, N;
Turner, R;
Field, R;
Oliver, SG;
Slater, N;
Dikicioglu, D;
(2019)
Metaheuristic approaches in biopharmaceutical process development data analysis.
Bioprocess and Biosystems Engineering
, 42
(9)
pp. 1399-1408.
10.1007/s00449-019-02147-0.
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Goh, H-Y;
Sulu, M;
Alosert, H;
Lewis, GL;
Josland, GD;
Merriman, DE;
(2019)
Applications of off-gas mass spectrometry in fed-batch mammalian cell culture.
Bioprocess and Biosystems Engineering
10.1007/s00449-019-02242-2.
(In press).
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Goldrick, S;
Duran-Villalobos, CA;
Jankauskas, K;
Lovett, D;
Farid, SS;
Lennox, B;
(2019)
Modern day monitoring and control challenges outlined on an industrial-scale benchmark fermentation process.
Computers and Chemical Engineering
, 130
, Article 106471. 10.1016/j.compchemeng.2019.05.037.
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Gruber, Pia;
(2019)
Challenges of Chemoenzymatic and Biocatalytic Reaction Cascades and Online Monitoring at a Microscale.
Doctoral thesis (Ph.D), UCL (University College London).
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H
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Hailes, H;
Ward, J;
Wang, Y;
Tappertzhofen, N;
Mendez-Sanchez, D;
Bawn, M;
Lyu, B;
(2019)
Design and use of de novo cascades for new benzylisoquinoline alkaloid biosynthesis.
Angewandte Chemie
, 58
(30)
pp. 10120-10125.
10.1002/anie.201902761.
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Hailes, HC;
Subrizi, F;
Benhamou, L;
Ward, J;
Sheppard, T;
(2019)
Aminopolyols from carbohydrates: the amination of sugars and sugar‐derived tetrahydrofurans with transaminases.
Angewandte Chemie International Edition
, 58
(12)
pp. 3854-3858.
10.1002/anie.201813712.
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Hales, JE;
Matmon, G;
Dalby, PA;
Ward, JM;
Aeppli, G;
(2019)
Virus lasers for biological detection.
Nature Communications
, 10
(1)
, Article 3594. 10.1038/s41467-019-11604-z.
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Heathman, TRJ;
Nienow, AW;
Rafiq, QA;
Coopman, K;
Kara, B;
Hewitt, CJ;
(2019)
Development of a process control strategy for the serum-free microcarrier expansion of human mesenchymal stem cells towards cost-effective and commercially viable manufacturing.
Biochemical Engineering Journal
, 141
pp. 200-209.
10.1016/j.bej.2018.10.018.
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I
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Isimite, J;
Baganz, F;
Hass, V;
(2019)
A systems engineering framework for the design of bioprocess operator training simulators.
In: Wang, Y, (ed.)
Proceedings of the 2018 International Seminar on Food Safety and Environmental Engineering (FSEE 2018).
EDP Sciences: Guangzhou, China.
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J
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Jankauskas, K;
Farid, SS;
(2019)
Multi-objective biopharma capacity planning under uncertainty using a flexible genetic algorithm approach.
Computers & Chemical Engineering
, 128
pp. 35-52.
10.1016/j.compchemeng.2019.05.023.
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Jankauskas, K;
Papageorgiou, LG;
Farid, SS;
(2019)
Fast genetic algorithm approaches to solving discrete-time mixed integer linear programming problems of capacity planning and scheduling of biopharmaceutical manufacture.
Computers and Chemical Engineering
, 121
pp. 212-223.
10.1016/j.compchemeng.2018.09.019.
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Jankauskas, Karolis;
(2019)
Biopharmaceutical Scheduling Using a Flexible Genetic Algorithm Approach.
Doctoral thesis (Ph.D), UCL (University College London).
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Jasulaityte, G;
Johansson, HJ;
Bracewell, DG;
(2019)
Chromatography process development aided by a dye‐based assay.
Journal of Chemical Technology & Biotechnology
, 95
(1)
pp. 132-141.
10.1002/jctb.6214.
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Johnson, Thomas Francis;
(2019)
Three dimensional representation and analysis of individual bead and packed bed scale chromatography using X-ray computed tomography and focused ion beam microscopy.
Doctoral thesis (Eng.D), UCL (University College London).
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Jury, E;
Manson, J;
Ciurtin, C;
Bradford, C;
McDonnell, T;
Isenberg, D;
Robinson, G;
(2019)
Characterization of a subset of patients with rheumatoid arthritis for whom current management strategies are inadequate.
ACR Open Rheumatology
, 1
(3)
pp. 145-155.
10.1002/acr2.1021.
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K
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Kolmar, JF;
Thum, O;
Baganz, F;
(2019)
Improving product specificity of whole-cell alkane oxidation in non-conventional media: a multivariate analysis approach.
Biotechnology Journal
, 14
(10)
, Article 1800581. 10.1002/biot.201800581.
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Kostas, ET;
Cooper, M;
Shepherd, BJ;
Robinson, JP;
(2019)
Identification of Bio-oil Compound Utilizing Yeasts Through Phenotypic Microarray Screening.
Waste and Biomass Valorization
10.1007/s12649-019-00636-7.
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Kostas, ET;
Williams, OSA;
Duran-Jimenez, G;
Tapper, AJ;
Cooper, M;
Meehan, R;
Robinson, JP;
(2019)
Microwave pyrolysis of Laminaria digitata to produce unique seaweed-derived bio-oils.
Biomass and Bioenergy
, 125
pp. 41-49.
10.1016/j.biombioe.2019.04.006.
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L
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Lara, AR;
Jaen, KE;
Folarin, O;
Keshavarz-Moore, E;
Buechs, J;
(2019)
Effect of the oxygen transfer rate on oxygen-limited production of plasmid DNA by Escherichia coli.
Biochemical Engineering Journal
, 150
, Article 107303. 10.1016/j.bej.2019.107303.
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Li, Y;
Ducci, A;
Micheletti, M;
(2019)
Mixing Time in Intermediate-Sized Orbitally Shaken Reactors with Small Orbital Diameters.
Chemical Engineering & Technology
, 42
(8)
pp. 1611-1617.
10.1002/ceat.201900063.
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Livanos, Maria;
(2019)
Production of DARPins in the Yeast Pichia pastoris.
Doctoral thesis (Ph.D), UCL (University College London).
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Lularevic, M;
Racher, AJ;
Jaques, C;
Kiparissides, A;
(2019)
Improving the accuracy of flux balance analysis through the implementation of carbon availability constraints for intracellular reactions.
Biotechnology and Bioengineering
, 116
(9)
pp. 2339-2352.
10.1002/bit.27025.
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M
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Maldonado, SL;
Krull, J;
Rasch, D;
Panjan, P;
Sesay, AM;
Marques, MPC;
Szita, N;
(2019)
Application of a multiphase microreactor chemostat for the determination of reaction kinetics of Staphylococcus carnosus.
Bioprocess and Biosystems Engineering
, 42
pp. 953-961.
10.1007/s00449-019-02095-9.
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Malik, S;
Hagopian, J;
Mohite, S;
Cao, L;
Els, LS;
Giannakopoulos, S;
Beckett, R;
... Parker, B; + view all
(2019)
Robotic Extrusion of Algae-Laden Hydrogels for Large-Scale Applications.
Global Challenges
, Article 1900064. 10.1002/gch2.201900064.
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Mante, J;
Gangadharan, N;
Sewell, DJ;
Turner, R;
Field, R;
Oliver, SG;
Slater, N;
(2019)
A heuristic approach to handling missing data in biologics manufacturing databases.
Bioprocess and Biosystems Engineering
, 42
(4)
pp. 657-663.
10.1007/s00449-018-02059-5.
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Marques, MP;
Boyd, A;
Polizzi, K;
Szita, N;
(2019)
Microfluidic devices towards personalized health and wellbeing.
Journal of Chemical Technology and Biotechnology
, 94
(8)
pp. 2412-2415.
10.1002/jctb.6009.
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Martin-Gutierrez, L;
Wilton, J;
Robinson, G;
McDonnell, T;
Isenberg, D;
Wincup, C;
Kalea, A;
... Ciurtin, C; + view all
(2019)
Designing a diet interventional study for autoimmune rheumatic disease: asking patients what they think.
Presented at: EULAR: Annual European Congress of Rheumatology, Madrid, Spain.
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Martinez, M;
Spitali, M;
Norrant, EL;
Bracewell, DG;
(2019)
Precipitation as an Enabling Technology for the Intensification of Biopharmaceutical Manufacture.
Trends in Biotechnology
, 37
(3)
pp. 237-241.
10.1016/j.tibtech.2018.09.001.
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McDonnell, T;
Wincup, C;
Buchholz, I;
Pericleous, C;
Giles, I;
Ripoll, V;
Cohen, H;
... Rahman, A; + view all
(2019)
The role of beta-2-glycoprotein I in health and disease associating structure with function: More than just APS.
Blood Reviews
, Article 100610. 10.1016/j.blre.2019.100610.
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Mohammed, Reema;
(2019)
Defining The Role Of Oxygen Tension In Human Pluripotent Stem Cell Fate Decisions.
Doctoral thesis (Ph.D), UCL (University College London).
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Morris, Christopher W;
(2019)
Protein Precipitation for the Purification of Therapeutic Protein.
Doctoral thesis (Eng.D), UCL (University College London).
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N
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Neves Dos Reis, Joana;
(2019)
Development of strategies for isolation and functional testing of cell lines for neuronal regeneration.
Doctoral thesis (Ph.D), UCL (University College London).
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O
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Oh, G;
Sirunyan, AM;
Tumasyan, A;
Adam, W;
Ambrogi, F;
Asilar, E;
Bergauer, T;
... Woods, N; + view all
(2019)
Beyond nPDFs effects : Prompt J/psi and psi(2S) production in pPb and pp collisions.
Nuclear Physics A
, 982
pp. 743-746.
10.1016/j.nuclphysa.2018.10.028.
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Oshinbolu, Sheun;
(2019)
Analysis of critical quality attributes in monoclonal antibodies for upstream process development.
Doctoral thesis (Eng.D), UCL (University College London).
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Oyebolu, FB;
Allmendinger, R;
Farid, SS;
Branke, J;
(2019)
Dynamic scheduling of multi-product continuous biopharmaceutical facilities: A hyper-heuristic framework.
Computers and Chemical Engineering
, 125
pp. 71-88.
10.1016/j.compchemeng.2019.03.002.
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P
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Panagopoulou, TI;
Rafiq, QA;
(2019)
CAR-T immunotherapies: Biotechnological strategies to improve safety, efficacy and clinical outcome through CAR engineering.
Biotechnology Advances
, 37
(7)
, Article 107411. 10.1016/j.biotechadv.2019.06.010.
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Partridge, TA;
Ahmed, M;
Choudhary, SB;
van der Walle, CF;
Patel, SM;
Bishop, SM;
Mantle, MD;
(2019)
Application of Magnetic Resonance to Assess Lyophilized Drug Product Reconstitution.
Pharmaceutical Research
, 36
(5)
p. 71.
10.1007/s11095-019-2591-x.
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Pathak, M;
Lintern, K;
Johnson, TF;
Nair, AM;
Mukherji, S;
Bracewell, DG;
Rathore, AS;
(2019)
Analytical tools for monitoring changes in physical and chemical properties of chromatography resin upon reuse.
Electrophoresis
, 40
(23-24)
pp. 3074-3083.
10.1002/elps.201900089.
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Pereira Chilima, Tania D.;
(2019)
Decisional Tools for Enabling Successful Manufacture and Commercialisation of Cell Therapy Products.
Doctoral thesis (Eng.D), UCL (University College London).
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Pericleous, C;
D'Souza, A;
McDonnell, T;
Ripoll, VM;
Leach, O;
Isenberg, D;
Giles, I;
(2019)
Antiphospholipid antibody levels in early systemic lupus erythematosus: are they associated with subsequent mortality and vascular events?
Rheumatology
, Article kez239. 10.1093/rheumatology/kez239.
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Planamente, S;
Frank, S;
(2019)
Bio-engineering of bacterial microcompartments: a mini review.
[Review].
Biochemical Society Transactions
, 47
(3)
pp. 765-777.
10.1042/BST20170564.
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Q
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Qin, H;
Dong, Z;
Wang, X;
Cheng, WA;
Wen, F;
Xue, W;
Sun, H;
... Kwak, LW; + view all
(2019)
CAR T cells targeting BAFF-R can overcome CD19 antigen loss in B cell malignancies.
Science Translational Medicine
, 11
(511)
, Article eaaw9414. 10.1126/scitranslmed.aaw9414.
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Qiong, L;
Gu, Q;
He, W;
(2019)
Resilience of Chinese Teachers: Why Perceived Work Conditions and Relational Trust Matter.
Measurement: Interdisciplinary Research and Perspectives
, 17
(3)
pp. 143-159.
10.1080/15366367.2019.1588593.
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R
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Raimes, William N.M.;
(2019)
An Automated Microfluidic Perfusion System for the Derivation of Induced Pluripotent Stem Cells.
Doctoral thesis (Ph.D), UCL (University College London).
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Robinson, G;
McDonnell, T;
Wincup, C;
Martin-Gutierrez, L;
Wilton, J;
Kalea, A;
Ciurtin, C;
... Jury, E; + view all
(2019)
Cardiovascular disease in SLE: what do patients think about using diet as a therapeutic?
Presented at: European League Against Rheumatism (EULAR) 2019, Madrid, Spain.
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Robinson, GA;
Mcdonnell, T;
Wincup, C;
Martin-Gutierrez, L;
Wilton, J;
Kalea, AZ;
Ciurtin, C;
... Jury, EC; + view all
(2019)
Diet and lupus: what do the patients think?
Lupus
, 28
(6)
pp. 755-763.
10.1177/0961203319845473.
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Robinson, MJ;
Matejtschuk, P;
Longstaff, C;
Dalby, PA;
(2019)
Selective stabilisation and destabilisation of protein domains in tissue-type plasminogen activator using formulation excipients.
Molecular Pharmaceutics
, 16
(2)
pp. 744-755.
10.1021/acs.molpharmaceut.8b01024.
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Roddan, R;
Gygli, G;
Sula, A;
Mendez-Sanchez, D;
Pleiss, J;
Ward, JM;
Keep, NH;
(2019)
Acceptance and Kinetic Resolution of α-Methyl-Substituted Aldehydes by Norcoclaurine Synthases.
ACS Catalysis
, 9
(10)
pp. 9640-9649.
10.1021/acscatal.9b02699.
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Ruscic, J;
Perry, C;
Mukhopadhyay, T;
Takeuchi, Y;
Bracewell, DG;
(2019)
Lentiviral Vector Purification Using Nanofiber Ion Exchange Chromatography.
Molecular Therapy: Methods & Clinical Development
, 15
pp. 52-62.
10.1016/j.omtm.2019.08.007.
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Rutley, James David;
(2019)
Evaluation of Single-Use Bioreactors for Rapid Development of Industrial Fermentation Processes.
Doctoral thesis (Eng.D), UCL (University College London).
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S
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Samaras, J;
Micheletti, M;
Ducci, A;
(2019)
Suspension and Mixing Characterization of Intermittent Agitation Modes in DASGIP Bioreactors.
Chemical Engineering and Technology
, 42
(8)
pp. 1587-1593.
10.1002/ceat.201900069.
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