Martinez, M;
Spitali, M;
Norrant, EL;
Bracewell, DG;
(2019)
Precipitation as an Enabling Technology for the Intensification of Biopharmaceutical Manufacture.
Trends in Biotechnology
, 37
(3)
pp. 237-241.
10.1016/j.tibtech.2018.09.001.
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Abstract
Advances in precipitation have demonstrated the capability of purifying therapeutic proteins such as antibodies from biological sources in a scalable and cost-effective manner. We discuss the latest developments in the unit operation for downstream processing applications and provide a perspective on exploring precipitation for bioprocess intensification.
| Type: | Article |
|---|---|
| Title: | Precipitation as an Enabling Technology for the Intensification of Biopharmaceutical Manufacture |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.tibtech.2018.09.001 |
| Publisher version: | https://doi.org/10.1016/j.tibtech.2018.09.001 |
| Language: | English |
| Additional information: | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
| Keywords: | Bioprocessing, continuous, precipitation, process intensification |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Biochemical Engineering |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10059542 |
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