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Precipitation as an Enabling Technology for the Intensification of Biopharmaceutical Manufacture

Martinez, M; Spitali, M; Norrant, EL; Bracewell, DG; (2019) Precipitation as an Enabling Technology for the Intensification of Biopharmaceutical Manufacture. Trends in Biotechnology , 37 (3) pp. 237-241. 10.1016/j.tibtech.2018.09.001. Green open access

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Abstract

Advances in precipitation have demonstrated the capability of purifying therapeutic proteins such as antibodies from biological sources in a scalable and cost-effective manner. We discuss the latest developments in the unit operation for downstream processing applications and provide a perspective on exploring precipitation for bioprocess intensification.

Type: Article
Title: Precipitation as an Enabling Technology for the Intensification of Biopharmaceutical Manufacture
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.tibtech.2018.09.001
Publisher version: https://doi.org/10.1016/j.tibtech.2018.09.001
Language: English
Additional information: This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Keywords: Bioprocessing, continuous, precipitation, process intensification
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Biochemical Engineering
URI: https://discovery.ucl.ac.uk/id/eprint/10059542
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