Browse by UCL Departments and Centres
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Number of items: 129.
A
Agbuduwe, Charles Eromosele;
(2024)
Investigating a Novel Gamma Delta (γδ) T Cell-Based Chimeric Antigen Receptor Therapy for Solid Tumours.
Doctoral thesis (Ph.D), UCL (University College London).
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Al Wattar, BH;
Rogozińska, E;
Vale, C;
Fisher, D;
Petersen, I;
Nicum, S;
Bannington, D;
... Freemantle, N; + view all
(2024)
Effectiveness and safety of menopause treatments: pitfalls of available evidence and future research need.
Climacteric
10.1080/13697137.2023.2297880.
(In press).
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Al-Yousuf, Hannah;
O'Nions, Jenny;
Wilson, Andrew J;
Gohil, Satyen;
Manson, Jessica J;
Payne, Elspeth M;
(2024)
Safety and efficacy of anakinra in hemophagocytic lymphohistiocytosis associated with acute leukemia.
Haematologica
10.3324/haematol.2023.283879.
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Albert, MC;
Uranga-Murillo, I;
Arias, M;
De Miguel, D;
Peña, N;
Montinaro, A;
Varanda, AB;
... Walczak, H; + view all
(2024)
Identification of FasL as a crucial host factor driving COVID-19 pathology and lethality.
Cell Death & Differentiation
10.1038/s41418-024-01278-6.
(In press).
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Alwyn Dart, D. Alwyn;
Koushyar, Sarah;
Uysal-Onganer, Pinar;
(2024)
Exploring the potential link between prostate cancer and magnetic fields.
Medical Hypotheses
, 189
, Article 111384. 10.1016/j.mehy.2024.111384.
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Appios, Anna;
Davies, James;
Sirvent, Sofia;
Henderson, Stephen;
Trzebanski, Sébastien;
Schroth, Johannes;
Law, Morven L;
... Bennett, Clare L; + view all
(2024)
Convergent evolution of monocyte differentiation in adult skin instructs Langerhans cell identity.
Science Immunology
, 9
(99)
, Article eadp0344. 10.1126/sciimmunol.adp0344.
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Arellano Ballestero, Helena;
(2024)
Defining the critical characteristics of Natural Killer cell memory.
Doctoral thesis (Ph.D), UCL (University College London).
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Astier, Clemence;
Ngo, Carine;
Colmet-Daage, Leo;
Marty, Virginie;
Bawa, Olivia;
Nicotra, Claudio;
Ngo-Camus, Maud;
... Postel-Vinay, Sophie; + view all
(2024)
Molecular profiling of biliary tract cancers reveals distinct genomic landscapes between circulating and tissue tumor DNA.
Experimental Hematology & Oncology
, 13
(1)
, Article 2. 10.1186/s40164-023-00470-7.
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B
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Bailey, Christopher;
(2024)
The prevalence, mutagenesis and evolution of focal copy number amplifications and extrachromosomal DNA in cancer.
Doctoral thesis (Ph.D), UCL (University College London).
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Balbi, Gustavo GM;
Ahmadzadeh, Yasaman;
Tektonidou, Maria G;
Pengo, Vittorio;
Sciascia, Savino;
Ugarte, Amaia;
Belmont, H Michael;
... Oliveira de Andrade, Danieli Castro; + view all
(2024)
Damage measured by Damage Index for Antiphospholipid Syndrome (DIAPS) in antiphospholipid antibody-positive patients included in the APS ACTION registry.
Rheumatology
, 63
(3)
pp. 772-779.
10.1093/rheumatology/kead292.
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Balukova, Andrea;
Bokea, Kalliopi;
Barber, Paul R;
Ameer-Beg, Simon M;
MacRobert, Alexander J;
Yaghini, Elnaz;
(2024)
Cellular Imaging and Time-Domain FLIM Studies of Meso-Tetraphenylporphine Disulfonate as a Photosensitising Agent in 2D and 3D Models.
International Journal of Molecular Sciences
, 25
(8)
, Article 4222. 10.3390/ijms25084222.
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Batty, Paul;
Fong, Sylvia;
Franco, Matteo;
Sihn, Choong-Ryoul;
Swystun, Laura L;
Afzal, Saira;
Harpell, Lori M;
... Lillicrap, David; + view all
(2024)
Vector integration and fate in the hemophilia dog liver multi-years following AAV-FVIII gene transfer.
Blood
10.1182/blood.2023022589.
(In press).
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Batty, Paul;
Lillicrap, David;
(2024)
Adeno-associated viral vector integration: implications for long-term efficacy and safety.
Journal of Thrombosis and Haemostasis
10.1016/j.jtha.2024.07.012.
(In press).
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Bayraktutan, Hulya;
Symonds, Peter;
Brentville, Victoria A;
Moloney, Cara;
Galley, Charlotte;
Bennett, Clare L;
Mata, Alvaro;
... Gurnani, Pratik; + view all
(2024)
Sparsely PEGylated poly(beta-amino ester) polyplexes enhance antigen specific T-cell response of a bivalent SARS-CoV-2 DNA vaccine.
Biomaterials
, Article 122647. 10.1016/j.biomaterials.2024.122647.
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Beaton, B;
Hughes, DA;
(2024)
Soluble mannose receptor: A potential biomarker in Gaucher disease.
European Journal of Haematology
10.1111/ejh.14171.
(In press).
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Breeze, Charles E;
Haugen, Eric;
Gutierrez-Arcelus, María;
Yao, Xiaozheng;
Teschendorff, Andrew;
Beck, Stephan;
Dunham, Ian;
... Berndt, Sonja I; + view all
(2024)
FORGEdb: a tool for identifying candidate functional variants and uncovering target genes and mechanisms for complex diseases.
Genome Biology
, 25
(1)
, Article 3. 10.1186/s13059-023-03126-1.
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Brimble, Mark;
Morton, Christopher L;
Winston, Stephen M;
Reeves, Isaiah L;
Spence, Yunyu;
Cheng, Pei-Hsin;
Zhou, Jungfang;
... Davidoff, Andrew M; + view all
(2024)
Pre-existing immunity to a nucleic acid contaminant-derived antigen mediates transaminitis and resultant diminished transgene expression in a mouse model of hepatic rAAV-mediated gene transfer.
Human Gene Therapy
10.1089/hum.2023.188.
(In press).
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Brown, Nicholas F;
Murray, Elizabeth R;
Cutmore, Lauren C;
Howard, Philip;
Masterson, Luke;
Zammarchi, Francesca;
Hartley, John A;
... Marshall, John F; + view all
(2024)
Integrin-αvβ6 targeted peptide-toxin therapy in a novel αvβ6-expressing immunocompetent model of pancreatic cancer.
Pancreatology
10.1016/j.pan.2024.02.013.
(In press).
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C
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Camilleri, Marquita;
(2024)
The Role of Autologous Stem Cell Transplantation in High-Risk Multiple Myeloma in the Novel Agent Era.
Doctoral thesis (M.D(Res)), UCL (University College London).
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Cecchi, Irene;
Radin, Massimo;
Foddai, Silvia Grazietta;
Barinotti, Alice;
Andrade, Danieli;
Tektonidou, Maria G;
Pengo, Vittorio;
... Sciascia, Savino; + view all
(2024)
ANA-positive versus ANA-negative Antiphospholipid Antibody-positive Patients: Results from the APS ACTION Clinical Database and Repository.
Rheumatology
, Article keae583. 10.1093/rheumatology/keae583.
(In press).
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Chen, Jingyu;
Sathiaseelan, Vijitha;
Reddy Chilamakuri, Chandra Sekkar;
Roamio Franklin, Valar Nila;
Jakwerth, Constanze A;
D'Santos, Clive;
Ringshausen, Ingo;
(2024)
ZAP-70 augments tonic B-cell receptor and CCR7 signaling in IGHV–unmutated chronic lymphocytic leukemia.
Blood Advances
, 8
(5)
pp. 1167-1178.
10.1182/bloodadvances.2022009557.
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Chia, Kim Hou;
Takaki, Hiroko;
Fujimitsu, Kazuyuki;
Darling, Sarah;
Zou, Juan;
Rappsilber, Juri;
Yamano, Hiroyuki;
(2024)
CDK1-PP2A-B55 interplay ensures cell cycle oscillation via Apc1-loop300.
Cell Reports
, 43
(5)
, Article 114155. 10.1016/j.celrep.2024.114155.
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Clements, Melanie;
Simpson Ragdale, Holly;
Garcia-Diaz, Claudia;
Parrinello, Simona;
(2024)
Generation of immunocompetent somatic glioblastoma mouse models through in situ transformation of subventricular zone neural stem cells.
STAR Protocols
, 5
(1)
, Article 102928. 10.1016/j.xpro.2024.102928.
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Constantinou, Georgia;
(2024)
Investigating immunity and cancer in a mouse model of PTEN hamartoma tumour syndrome (PHTS).
Doctoral thesis (Ph.D), UCL (University College London).
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Crolley, Valerie;
Bridgewater, John;
(2024)
Futibatinib for the Treatment of Previously Treated, Unresectable, Locally Advanced or Metastatic Intrahepatic Cholangiocarcinoma with Fibroblast Growth Factor Receptor 2 (FGFR2) Gene Fusions or Other Rearrangements.
touchREVIEWS in Oncology & Haematology
, 20
(1)
pp. 12-19.
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D
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Dart, D.Alwyn;
Bevan, Charlotte L;
Uysal-Onganer, Pinar;
Jiang, Wen Guo;
(2024)
Analysis of androgen receptor expression and activity
in the mouse brain.
Scientific Reports
, 14
, Article 11115. 10.1038/s41598-024-61733-9.
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de Tute, Ruth;
Counsell, Nicholas;
Clifton-Hadley, Laura;
D'Sa, Shirley;
Pratt, Guy;
Campbell, Gavin;
Campbell, Lauren;
... Auer, Rebecca; + view all
(2024)
Long-term outcomes by bone marrow B-cell depletion from the R2W trial of bortezomib with cyclophosphamide and rituximab in Waldenstrőm macroglobulinaemia.
Leukemia
, 38
pp. 822-828.
10.1038/s41375-024-02162-5.
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Dias, J;
Garcia, J;
Agliardi, G;
Roddie, C;
(2024)
CAR-T cell manufacturing landscape—Lessons from the past decade and considerations for early clinical development.
Molecular Therapy Methods and Clinical Development
, 32
(2)
, Article 101250. 10.1016/j.omtm.2024.101250.
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Dillon, Magnus T;
Guevara, Jeane;
Mohammed, Kabir;
Patin, Emmanuel C;
Smith, Simon A;
Dean, Emma;
Jones, Gemma N;
... Harrington, Kevin J; + view all
(2024)
Durable responses to ATR inhibition with ceralasertib in tumors with genomic defects and high inflammation.
Journal of Clinical Investigation
, 134
(2)
, Article e175369. 10.1172/JCI175369.
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E
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Edeline, Julien;
Bridgewater, John;
Campillo-Gimenez, Boris;
Neveu, Estelle;
Phelip, Jean-Marc;
Neuzillet, Cindy;
Boudjema, Karim;
... Lamarca, Angela; + view all
(2024)
Chemotherapy with or without selective internal radiation therapy for intrahepatic cholangiocarcinoma: Data from clinical trials.
Hepatology
, 79
(1)
pp. 96-106.
10.1097/HEP.0000000000000544.
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Efthymiou, Maria;
Bertolaccini, Maria Laura;
Cohen, Hannah;
(2024)
Viewpoint: Lupus anticoagulant detection and interpretation in antiphospholipid syndrome.
Rheumatology
, 63
(SI)
SI54-SI63.
10.1093/rheumatology/kead623.
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El-Khoueiry, AB;
Trojan, J;
Meyer, T;
Yau, T;
Melero, I;
Kudo, M;
Hsu, C;
... Sangro, B; + view all
(2024)
Nivolumab in sorafenib-naive and sorafenib-experienced patients with advanced hepatocellular carcinoma: 5-year follow-up from CheckMate 040.
Annals of Oncology
10.1016/j.annonc.2023.12.008.
(In press).
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Enfield, Katey SS;
Colliver, Emma;
Lee, Claudia SY;
Magness, Alastair;
Moore, David A;
Sivakumar, Monica;
Grigoriadis, Kristiana;
... Angelova, Mihaela; + view all
(2024)
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer.
Cancer Discovery
, 14
(1)
pp. 1-30.
10.1158/2159-8290.CD-23-1380.
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Enshaei, A;
Joy, M;
Butler, E;
Kirkwood, AA;
Messina, M;
Pavoni, C;
Morgades, M;
... Moorman, AV; + view all
(2024)
A robust and validated integrated prognostic index for defining risk groups in adult acute lymphoblastic leukemia: an EWALL collaborative study.
Blood Advances
, 8
(5)
pp. 1155-1166.
10.1182/bloodadvances.2023011661.
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F
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Ferrari, Mathieu;
Righi, Matteo;
Baldan, Vania;
Wawrzyniecka, Patrycja;
Bulek, Anna;
Kinna, Alexander;
Ma, Biao;
... Pule, Martin; + view all
(2024)
Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies.
Nature Communications
, 15
, Article 1583. 10.1038/s41467-024-45854-3.
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Ferreira Lopes, Joao Andre;
(2024)
A framework to quantify the quality-of-life value of progression-free survival in cancer clinical trials.
Doctoral thesis (Ph.D), UCL (University College London).
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Fittall, MW;
Brewer, M;
de Boisanger, J;
Kviat, L;
Babiker, A;
Taylor, H;
Saran, F;
... Rosenfelder, N; + view all
(2024)
Predicting Survival with Brain Metastases in the Stereotactic Radiosurgery Era: are Existing Prognostic Scores Still Relevant? Or Can we do Better?
Clinical Oncology
10.1016/j.clon.2024.01.037.
(In press).
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Fotopoulou, C;
Hall, M;
Lord, R;
Miller, R;
Sundar, S;
Roebuck, N;
Fildes, L;
... Ledermann, J; + view all
(2024)
Perspectives of Healthcare Professionals on the Management and Treatment of Advanced Ovarian Cancer in the UK: Results From the KNOW-OC Survey.
Clinical Oncology
, 36
(1)
e1-e10.
10.1016/j.clon.2023.10.052.
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Fowler, Daniel;
Barisa, Marta;
Southern, Alba;
Nattress, Callum;
Hawkins, Elizabeth;
Vassalou, Eleni;
Kanouta, Angeliki;
... Fisher, Jonathan; + view all
(2024)
Payload-delivering engineered γδ T cells display enhanced cytotoxicity, persistence, and efficacy in preclinical models of osteosarcoma.
Science Translational Medicine
, 16
(749)
, Article eadg9814. 10.1126/scitranslmed.adg9814.
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G
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Geukens, Tatjana;
Maetens, Marion;
Hooper, Jody E;
Oesterreich, Steffi;
Lee, Adrian;
Miller, Lori;
Atkinson, Jenny M;
... Desmedt, Christine; + view all
(2024)
Research autopsy programmes in oncology: shared experience from 14 centres across the world.
The Journal of Pathology
10.1002/path.6271.
(In press).
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Ghimire, Prajwal;
Kinnersley, Ben;
Karami, Golestan;
Arumugam, Prabhu;
Houlston, Richard;
Ashkan, Keyoumars;
Modat, Marc;
(2024)
Radiogenomic biomarkers for immunotherapy in glioblastoma: A systematic review of magnetic resonance imaging studies.
Neuro-Oncology Advances
, 6
(1)
, Article vdae055. 10.1093/noajnl/vdae055.
(In press).
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Ghorashian, Sara;
Lucchini, Giovanna;
Richardson, Rachel;
Nguyen, Kyvi;
Terris, Craig;
Guvenel, Aleks;
Oporto Espuelas, Macarena;
... Amrolia, Persis J; + view all
(2024)
CD19/CD22 targeting with co-transduced CAR T-cells to prevent antigen negative relapse after CAR T-cell therapy of B-ALL.
Blood
, 143
(2)
pp. 118-123.
10.1182/blood.2023020621.
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Giurgiu, M;
Wittstruck, N;
Rodriguez-Fos, E;
González, RC;
Brückner, L;
Krienelke-Szymansky, A;
Helmsauer, K;
... Henssen, AG; + view all
(2024)
Decoil: Reconstructing Extrachromosomal DNA Structural Heterogeneity from Long-Read Sequencing Data.
In:
Research in Computational Molecular Biology. RECOMB 2024.
(pp. pp. 406-411).
Springer, Cham
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Giurgiu, Madalina;
Wittstruck, Nadine;
Rodriguez-Fos, Elias;
Chamorro Gonzalez, Rocio;
Brueckner, Lotte;
Krienelke-Szymansky, Annabell;
Helmsauer, Konstantin;
... Henssen, Anton G; + view all
(2024)
Reconstructing extrachromosomal DNA structural heterogeneity from long-read sequencing data using Decoil.
Genome Research
10.1101/gr.279123.124.
(In press).
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Glasbey, J;
Beggs, A;
Glimelius, B;
Gray, R;
Handley, K;
Laurberg, S;
Magill, L;
... Furniss, D; + view all
(2024)
Risk of Bowel Obstruction in Patients Undergoing Neoadjuvant Chemotherapy for High-risk Colon Cancer: A Nested Case-control-matched Analysis of an International, Multicenter, Randomized Controlled Trial (FOxTROT).
Annals of Surgery
, 280
(2)
pp. 283-293.
10.1097/SLA.0000000000006145.
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Goh, Vicky;
Mallett, Susan;
Boulter, Victor;
Glynne-Jones, Robert;
Khan, Saif;
Lessels, Sarah;
Patel, Dominic;
... Halligan, Steve; + view all
(2024)
Multivariable prognostic modelling to improve prediction of colorectal cancer recurrence: the PROSPeCT trial.
European Radiology
10.1007/s00330-024-10803-7.
(In press).
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Gong, Grace Q;
Vanhaesebroeck, Bart;
(2024)
Precision Targeting of Mutant PI3Kα.
Cancer Discovery
, 14
(2)
pp. 204-207.
10.1158/2159-8290.cd-23-1392.
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Grigoriadis, Kristiana;
Huebner, Ariana;
Bunkum, Abigail;
Colliver, Emma;
Frankell, Alexander M;
Hill, Mark S;
Thol, Kerstin;
... McGranahan, Nicholas; + view all
(2024)
CONIPHER: a computational framework for scalable phylogenetic reconstruction with error correction.
Nature Protocols
, 19
pp. 159-183.
10.1038/s41596-023-00913-9.
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Grillone, Katia;
Ascrizzi, Serena;
Cremaschi, Paolo;
Amato, Jussara;
Polerà, Nicoletta;
Croci, Ottavio;
Rocca, Roberta;
... Tassone, Pierfrancesco; + view all
(2024)
An unbiased lncRNAs dropout CRISPR-Cas9 screen reveals RP11-350G8.5 as a novel therapeutic target for Multiple Myeloma.
Blood
10.1182/blood.2023021991.
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H
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Hackshaw, Allan;
Fajardo, Otto;
Dafni, Urania;
Gelderblom, Hans;
Garrido, Pilar;
Siena, Salvatore;
Taylor, Matthew H;
... Nikolaidis, Christos; + view all
(2024)
Characteristics and Survival Outcomes of Patients With Metastatic RET Fusion-Positive Solid Tumors Receiving Non-RET Inhibitor Standards of Care in a Real-World Setting.
JCO Precision Oncology
, 8
(8)
, Article e2300334. 10.1200/PO.23.00334.
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Hall Hickman, Alexander;
Jenner, Richard G;
(2024)
Apparent RNA bridging between PRC2 and chromatin is an artifact of non-specific chromatin precipitation upon RNA degradation.
Cell Reports
, 43
(3)
, Article 113856. 10.1016/j.celrep.2024.113856.
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Halliday, Neil;
Eden, Nadia;
Somers, Henry;
Burke, Niall;
Silva, Hiroshi;
Brito, Camila Gx;
Hall, Andrew;
... Thorburn, Douglas; + view all
(2024)
Common variable immunodeficiency disorder-related liver disease is common and results in portal hypertension and an increased risk of death.
Hepatology Communications
, 8
(1)
, Article e0322. 10.1097/HC9.0000000000000322.
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Haran, Shaun;
Chindera, Kantaraja;
Sabry, May;
Wilkinson, Nafisa;
Arora, Rupali;
Zubiak, Agnieszka;
Bartlett, Thomas E;
... Widschwendter, Martin; + view all
(2024)
Natural Killer Cell Dysfunction in Premenopausal BRCA1 Mutation Carriers: A Potential Mechanism for Ovarian Carcinogenesis.
Cancers
, 16
(6)
, Article 1186. 10.3390/cancers16061186.
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Hessey, Sonya;
(2024)
Tumour evolution and immune evasion in lung cancer from diagnosis to death.
Doctoral thesis (Ph.D), UCL (University College London).
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Hodder, Angus;
Mishra, Avijeet K;
Enshaei, Amir;
Baird, Susan;
Elbeshlawi, Ismail;
Bonney, Denise;
Clesham, Katherine;
... Vora, Ajay; + view all
(2024)
Blinatumomab for First-Line Treatment of Children and Young Persons With B-ALL.
Journal of Clinical Oncology
, 42
(8)
pp. 907-914.
10.1200/JCO.23.01392.
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Hoelzer, D;
Bassan, R;
Boissel, N;
Roddie, C;
Ribera, JM;
Jerkeman, M;
ESMO Guidelines Committee;
(2024)
ESMO Clinical Practice Guideline interim update on the use of targeted therapy in acute lymphoblastic leukaemia.
Annals of Oncology
, 35
(1)
pp. 15-28.
10.1016/j.annonc.2023.09.3112.
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Horna, Pedro;
Weybright, Matthew J;
Ferrari, Mathieu;
Jungherz, Dennis;
Peng, YaYi;
Akbar, Zulaikha;
Tudor Ilca, F;
... Olteanu, Horatiu; + view all
(2024)
Dual T-cell constant β chain (TRBC)1 and TRBC2 staining for the identification of T-cell neoplasms by flow cytometry.
Blood Cancer Journal
, 14
(1)
, Article 34. 10.1038/s41408-024-01002-0.
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Hoskin, Peter J;
Reczko, Krystyna;
Rashid, Memuna;
Hackshaw, Allan;
Lopes, Andres;
SCORAD Investigators;
(2024)
Quality-of-life outcomes in metastatic spinal cord compression: findings from the SCORAD trial.
JNCI: Journal of the National Cancer Institute
, Article djae039. 10.1093/jnci/djae039.
(In press).
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Huang, Shiran;
(2024)
Investigating PBD Dimer-based Antibody-Drug Conjugates (ADCs).
Doctoral thesis (Ph.D), UCL (University College London).
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Hwang, Angela;
Mehra, Vedika;
Chhetri, Jyoti;
Ali, Samira;
Tran, Maxine;
Roddie, Claire;
(2024)
Current Treatment Options for Renal Cell Carcinoma: Focus on
Cell-Based Immunotherapy.
Cancers
, 16
(6)
, Article 1209. 10.3390/cancers16061209.
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Hynds, Robert E;
Huebner, Ariana;
Pearce, David R;
Hil, Mark S;
Akarca, Ayse U;
Moore, David A;
Ward, Sophia;
... Swanton, Charles; + view all
(2024)
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models.
Nature Communications
, 15
, Article 4653. 10.1038/s41467-024-47547-3.
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Hynds, Robert E;
Magin, Chelsea M;
Ikonomou, Laertis;
Aschner, Yael;
Beers, Michael F;
Burgess, Janette K;
Heise, Rebecca L;
... Ryan, Amy L; + view all
(2024)
Stem Cells, Cell Therapies and Bioengineering in Lung Biology and Diseases 2023.
American Journal of Physiology: Lung Cellular and Molecular Physiology
10.1152/ajplung.00052.2024.
(In press).
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I
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Iacoboni, Gloria;
Navarro, Víctor;
Martín-López, Ana África;
Rejeski, Kai;
Kwon, Mi;
Jalowiec, Katarzyna Aleksandra;
Amat, Paula;
... Barba, Pere; + view all
(2024)
Recent Bendamustine Treatment Before Apheresis Has a Negative Impact on Outcomes in Patients With Large B-Cell Lymphoma Receiving Chimeric Antigen Receptor T-Cell Therapy.
Journal of Clinical Oncology
, 42
(2)
pp. 205-217.
10.1200/JCO.23.01097.
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J
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Jacobson, Daniel Hadar;
(2024)
Multi-scale characterisation of homologous
recombination deficiency in breast cancer and
therapeutic implications.
Doctoral thesis (Ph.D), UCL (University College London).
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Jahangir, CA;
Page, DB;
Broeckx, G;
Gonzalez, CA;
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