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Number of items at this level: 154.

A

Abbas, SH; Pickett, E; Lomas, DA; Thorburn, D; Gooptu, B; Hurst, JR; Marshall, A; (2020) Non-invasive testing for liver pathology in alpha-1 antitrypsin deficiency. BMJ Open Respiratory Research , 7 (1) , Article e000820. 10.1136/bmjresp-2020-000820. Green open access
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Agustí, A; Edwards, LD; Rennard, SI; MacNee, W; Tal-Singer, R; Miller, BE; Vestbo, J; ... Evaluation of COPD Longitudinally to Identify Predictive Surroga; + view all (2012) Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype. PLoS One , 7 (5) , Article e37483. 10.1371/journal.pone.0037483. Green open access
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Al-Hatimy, Fatima; Farooq, Abdulaziz; Al Abiad, Mohamad; Yerramsetti, Shilpi; Al-Nesf, Maryam Ali; Manickam, Chidambaram; Al-Thani, Mohammed H; ... Al-Maadheed, Mohammed; + view all (2022) A Retrospective Study of Non-Communicable Diseases amongst Blue-Collar Migrant Workers in Qatar. International Journal of Environmental Research and Public Health , 19 (4) , Article 2266. 10.3390/ijerph19042266. Green open access
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Andoniadou, CL; Signore, M; Sajedi, E; Gaston-Massuet, C; Kelberman, D; Burns, AJ; Itasaki, N; ... Martinez-Barbera, JP; + view all (2007) Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain. DEVELOPMENT , 134 (8) 1499 - 1508. 10.1242/dev.02829. Green open access
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Ansari, T; Lange, P; Southgate, A; Greco, K; Carvalho, C; Partington, L; Bullock, A; ... Birchall, MA; + view all (2017) Stem Cell-Based Tissue-Engineered Laryngeal Replacement. Stem Cells Translational Medicine , 6 (2) pp. 677-687. 10.5966/sctm.2016-0130. Green open access
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B

Bafadhel, M; Barnes, N; Bourke, SC; Compton, C; Criner, GJ; Dransfield, MT; Halpin, DMG; ... Singh, D; + view all (2021) A single blood eosinophil count measurement is as good as two for prediction of ICS treatment response in the IMPACT trial. European Respiratory Journal , 58 (3) , Article 2004522. 10.1183/13993003.04522-2020. Green open access
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Bailey, SR; Townsend, CL; Dent, H; Mallet, C; Tsaliki, E; Riley, EM; Noursadeghi, M; ... Field, N; + view all (2017) A pilot study to understand feasibility and acceptability of stool and cord blood sample collection for a large-scale longitudinal birth cohort. BMC Pregnancy Childbirth , 17 , Article 439. 10.1186/s12884-017-1627-7. Green open access
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Baker, D; Pryce, G; Visintin, C; Sisay, S; Bondarenko, AI; Ho, WSV; Jackson, SJ; ... Selwood, DL; + view all (2017) Big conductance calcium-activated potassium channel openers control spasticity without sedation. British Journal of Pharmacology , 174 (16) pp. 2662-2681. 10.1111/bph.13889. Green open access
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Bazzan, E; Tinè, M; Biondini, D; Benetti, R; Baraldo, S; Turato, G; Fagiuoli, S; ... Cosio, MG; + view all (2018) α1-Antitrypsin Polymerizes in Alveolar Macrophages of Smokers With and Without α1-Antitrypsin Deficiency. Chest , 154 (3) pp. 607-616. 10.1016/j.chest.2018.04.039. Green open access
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Bellingan, GJ; Xu, P; Cooksley, H; Cauldwell, H; Shock, A; Bottoms, S; Haslett, C; ... Laurent, GJ; + view all (2002) Adhesion molecule-dependent mechanisms regulate the rate of macrophage clearance during the resolution of peritoneal inflammation. J EXP MED , 196 (11) 1515 - 1521. 10.1084/jem.20011794. Green open access
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Birgisdottir, AB; Mouilleron, S; Bhujabal, Z; Wirth, M; Sjottem, E; Evjen, G; Zhang, W; ... Johansen, T; + view all (2019) Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy , 15 (8) pp. 1333-1355. 10.1080/15548627.2019.1581009. Green open access
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Bourdin, A; Criner, G; Devouassoux, G; Dransfield, M; Halpin, DMG; Han, MK; Jones, CE; ... Hanania, NA; + view all (2021) InforMing the PAthway of COPD Treatment (IMPACT Trial) Single-Inhaler Triple Therapy (Fluticasone Furoate/Umeclidinium/Vilanterol) Versus Fluticasone Furoate/Vilanterol and Umeclidinium/Vilanterol in Patients With COPD: Analysis o the Western Europe and North America Regions. Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation , 8 (1) pp. 76-90. 10.15326/jcopdf.2020.0158. Green open access
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Bouton, Marie-Christine; Geiger, Margarethe; Sheffield, William P; Irving, James A; Lomas, David A; Song, Sihong; Satyanarayanan, Ritvik S; ... Lucas, Alexandra R; + view all (2023) The under-appreciated world of the serpin family of serine proteinase inhibitors. EMBO Molecular Medicine , Article e17144. 10.15252/emmm.202217144. Green open access
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Briggs, AH; Baker, T; Risebrough, NA; Chambers, M; Gonzalez-McQuire, S; Ismaila, AS; Exuzides, A; ... Lomas, DA; + view all (2017) Development of the Galaxy Chronic Obstructive Pulmonary Disease (COPD) Model Using Data from ECLIPSE: Internal Validation of a Linked-Equations Cohort Model. Medical Decision Making , 37 (4) pp. 469-480. 10.1177/0272989X16653118. Green open access
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Broome, AH; Nabugodi, M; Sreenan, N; Harvey, L; (2014) Editor's note. Tropos , 2 (1) pp. 2-3. 10.14324/111.2057-2212.001. Green open access
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Burton, EA; (2016) Extrastriate form and motion processing in cone dysfunction and normal vision. Doctoral thesis , UCL (University College London). Green open access
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Busch, R; Hobbs, BD; Zhou, J; Castaldi, PJ; McGeachie, MJ; Hardin, ME; Hawrylkiewicz, I; ... NETT Genetics, ECLIPSE, ICGN, and COPDGene Investigators, .; + view all (2017) Genetic Association and Risk Scores in a COPD Meta-Analysis of 16,707 Subjects. American Journal of Respiratory Cell and Molecular Biology , 57 (1) pp. 35-46. 10.1165/rcmb.2016-0331OC. Green open access
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Butler, CR; Hynds, RE; Crowley, C; Gowers, KH; Partington, L; Hamilton, NJ; Carvalho, C; ... Janes, SM; + view all (2017) Vacuum-assisted decellularization: an accelerated protocol to generate tissue-engineered human tracheal scaffolds. Biomaterials , 124 pp. 95-105. 10.1016/j.biomaterials.2017.02.001. Green open access
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C

Celli, B; Locantore, N; Yates, JC; Bakke, P; Calverley, PMA; Crim, C; Coxson, HO; ... Evaluation of COPD Longitudinally to Identify Predictive Surroga; + view all (2021) Markers of disease activity in COPD: an 8-year mortality study in the ECLIPSE cohort. European Respiratory Journal , 57 (3) , Article 2001339. 10.1183/13993003.01339-2020. Green open access
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Cheeseman, HM; Day, S; McFarlane, L; Fleck, S; Miller, A; Cole, T; Sousa-Santos, N; ... Shattock, R; + view all (2018) Combined skin and muscle DNA priming provides enhanced humoral responses to an HIV-1 clade C envelope vaccine. Human Gene Therapy , 29 (9) pp. 1011-1028. 10.1089/hum.2018.075. Green open access
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Chow, PS; (2016) ‘A Symptom of Something Real’: The Øresund Region on Film and Television, 1999–2014. Doctoral thesis , UCL (University College London). Green open access
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Chow, PS; (2010) Losing Control: Lars von Trier and the Production of Authenticity and the Auteur. Masters thesis , National University of Singapore.

Cosgrove, CA; Lacey, CJ; Cope, AV; Bartolf, A; Morris, G; Yan, C; Baden, S; ... Shattock, RJ; + view all (2016) Comparative Immunogenicity of HIV-1 gp140 Vaccine Delivered by Parenteral, and Mucosal Routes in Female Volunteers; MUCOVAC2, A Randomized Two Centre Study. PLoS One , 11 (5) , Article e0152038. 10.1371/journal.pone.0152038. Green open access
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D

Day, NC; Kumar, S; Criner, G; Dransfield, M; Halpin, DMG; Han, MK; Jones, CE; ... Lipson, DA; + view all (2020) Single-inhaler triple therapy fluticasone furoate/umeclidinium/vilanterol versus fluticasone furoate/vilanterol and umeclidinium/vilanterol in patients with COPD: results on cardiovascular safety from the IMPACT trial. Respiratory Research , 21 , Article 139. 10.1186/s12931-020-01398-w. Green open access
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Dickens, JA; Ordonez, A; Chambers, JE; Beckett, AJ; Patel, V; Malzer, E; Dominicus, CS; ... Marciniak, SJ; + view all (2016) The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z-alpha(1)-antitrypsin. FASEB Journal , 30 (12) pp. 4083-4097. 10.1096/fj.201600430R. Green open access
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Dransfield, MT; Crim, C; Criner, GJ; Day, NC; Halpin, DMG; Han, MK; Jones, CE; ... Lange, P; + view all (2020) Risk of Exacerbation and Pneumonia with Single Inhaler Triple Versus Dual Therapy in IMPACT. Annals of the American Thoracic Society 10.1513/AnnalsATS.202002-096OC. (In press). Green open access
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Drewry, DH; Wells, CI; Andrews, DM; Angell, R; Al-Ali, H; Axtman, AD; Capuzzi, SJ; ... Willson, TM; + view all (2017) Progress towards a public chemogenomic set for protein kinases and a call for contributions. PLOS ONE , 12 (8) , Article e0181585. 10.1371/journal.pone.0181585. Green open access
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E

Elliott, MJ; Butler, CR; Varanou-Jenkins, A; Partington, L; Carvalho, C; Samuel, E; Crowley, C; ... Birchall, MA; + view all (2017) Tracheal Replacement Therapy with a Stem Cell-Seeded Graft: Lessons from Compassionate Use Application of a GMP-Compliant Tissue-Engineered Medicine. Stem Cells Translational Medicine , 6 (6) pp. 1458-1464. 10.1002/sctm.16-0443. Green open access
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Elliston, ELK; Lomas, DA; Irving, JA; (2018) In Vitro Approaches for the Assessment of Serpin Polymerization. Methods in Molecular Biology , 1826 pp. 87-107. 10.1007/978-1-4939-8645-3_6. Green open access
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Engleitner, H; Jha, A; Herron, D; Nelson, A; Rees, G; McNally, N; Williams, B; (2021) Enrolment in clinical research at UCLH and geographically distributed indices of deprivation [version 1; peer review: awaiting peer review]. Wellcome Open Research , 6 , Article 342. 10.12688/wellcomeopenres.17300.1. Green open access
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ENOMOTO, K; (2012) Psychological factors associated with pain 24 hours post-tooth extraction. Doctoral thesis , UCL (University College London). Green open access
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F

Faravelli, G; Raimondi, S; Marchese, L; Partridge, FA; Soria, C; Mangione, PP; Canetti, D; ... Giorgetti, S; + view all (2019) C. elegans expressing D76N β_{2}-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis. Scientific Reports , 9 , Article 19960. 10.1038/s41598-019-56498-5. Green open access
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Faull, SV; Elliston, ELK; Gooptu, B; Jagger, AM; Aldobiyan, I; Redzej, A; Badaoui, M; ... Lomas, DA; + view all (2020) The structural basis for Z α₁-antitrypsin polymerization in the liver. Science Advances , 6 (43) , Article eabc1370. 10.1126/sciadv.abc1370. Green open access
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Fisk, M; Cheriyan, J; Mohan, D; Forman, J; Mäki-Petäjä, KM; McEniery, CM; Fuld, J; ... Wilkinson, IB; + view all (2018) The p38 mitogen activated protein kinase inhibitor losmapimod in chronic obstructive pulmonary disease patients with systemic inflammation, stratified by fibrinogen: A randomised double-blind placebo-controlled trial. PLoS One , 13 (3) , Article e0194197. 10.1371/journal.pone.0194197. Green open access
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Fisk, M; McEniery, CM; Gale, N; Mäki-Petäjä, K; Forman, JR; Munnery, M; Woodcock-Smith, J; ... ERICA Consortium and ACCT Investigators; + view all (2018) Surrogate Markers of Cardiovascular Risk and Chronic Obstructive Pulmonary Disease: A Large Case-Controlled Study. Hypertension , 71 (3) pp. 499-506. 10.1161/HYPERTENSIONAHA.117.10151. Green open access
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Flynn, MD; Beasley, P; Tooke, JE; (1992) Adrenal suppression with intranasal betamethasone drops. Journal of Laryngology and Otology , 106 (9) 827 - 828. 10.1017/S0022215100120997. Green open access
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Fromme, M; Schneider, CV; Pereira, V; Hamesch, K; Pons, M; Reichert, MC; Benini, F; ... Strnad, P; + view all (2021) Hepatobiliary phenotypes of adults with alpha-1 antitrypsin deficiency. Gut 10.1136/gutjnl-2020-323729. (In press). Green open access
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G

Ghosh, AJ; Hobbs, BD; Moll, M; Saferali, A; Boueiz, A; Yun, JH; Sciurba, F; ... Hersh, CP; + view all (2022) Alpha-1 Antitrypsin MZ Heterozygosity Is an Endotype of Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine , 205 (3) pp. 313-323. 10.1164/rccm.202106-1404OC. Green open access
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Goodwin, GB; (2014) The double movement in the Andes: land reform, land markets, and indigenous mobilisation in Highland Ecuador (1964-1994). Doctoral thesis , UCL (University College London). Green open access
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Gordon, C; Yardley, S; Lomas, DA; Edwards, SJL; (2021) Limitations to Contingency Measures: Reflections from COVID-19 Surges in the UK. The American Journal of Bioethics , 21 (8) pp. 31-34. 10.1080/15265161.2021.1940365. Green open access
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Greene, CM; Marciniak, SJ; Teckman, J; Ferrarotti, I; Brantly, ML; Lomas, DA; Stoller, JK; (2018) Author Correction: α1-Antitrypsin deficiency. [Corrigendum]. Nature Reviews Disease Primers , 4 , Article 40. 10.1038/s41572-018-0043-2. Green open access
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Greene, CM; Marciniak, SJ; Teckman, J; Ferrarotti, I; Brantly, ML; Lomas, DA; Stoller, JK; (2016) α1-Antitrypsin deficiency. Nature Reviews Disease Primers , 2 , Article 16051. 10.1038/nrdp.2016.51. Green open access
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Guzman, JD; Pesnot, T; Barrera, DA; Davies, HM; McMahon, E; Evangelopoulos, D; Mortazavi, PN; ... Bhakta, S; + view all (2015) Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase. J Antimicrob Chemother , 70 (6) pp. 1691-1703. 10.1093/jac/dkv010. Green open access
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H

Haidari, G; Cope, A; Miller, A; Venables, S; Yan, C; Ridgers, H; Reijonen, K; ... Shattock, RJ; + view all (2017) Combined skin and muscle vaccination differentially impact the quality of effector T cell functions: the CUTHIVAC-001 randomized trial. Scientific Reports , 7 , Article 13011. 10.1038/s41598-017-13331-1. Green open access
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Haidari, G; Day, S; Wood, M; Ridgers, H; Cope, A; Fleck, S; Yan, C; ... Shattock, RJ; + view all (2019) The Safety and Immunogenicity of GTU (R) MultiHIV DNA Vaccine Delivered by Transcutaneous and Intramuscular Injection With or Without Electroporation in HIV-1 Positive Subjects on Suppressive ART. Frontiers in Immunology , 10 , Article 2911. 10.3389/fimmu.2019.02911. Green open access
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Halpin, DMG; Birk, R; Brealey, N; Criner, GJ; Dransfield, MT; Hilton, E; Lomas, DA; ... Lipson, DA; + view all (2018) Single-inhaler triple therapy in symptomatic COPD patients: FULFIL subgroup analyses. ERJ Open Research , 4 (2) , Article 00119-2017. 10.1183/23120541.00119-2017. Green open access
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Halpin, DMG; Criner, GJ; Dransfield, MT; Han, MK; Hartley, B; Harvey, C; Jones, CE; ... Lipson, DA; + view all (2020) Triple Versus Dual Combination Therapy in Chronic Obstructive Pulmonary Disease in Asian Countries: Analysis of the IMPACT Trial. Pulmonary Therapy 10.1007/s41030-020-00136-3. (In press). Green open access
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Halpin, DMG; Dransfield, MT; Han, MK; Jones, CE; Kilbride, S; Lange, P; Lipson, DA; ... Criner, GJ; + view all (2020) The Effect of Exacerbation History on Outcomes in the IMPACT Trial. European Respiratory Journal , 55 , Article 1901921. 10.1183/13993003.01921-2019. Green open access
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Hamid, S; Donaldson, IA; Hu, Y; Rodell, R; Villarini, B; Bonmati, E; Tranter, P; ... Ahmed, HU; + view all (2019) The SmartTarget Biopsy Trial: A Prospective, Within-person Randomised, Blinded Trial Comparing the Accuracy of Visual-registration and Magnetic Resonance Imaging/Ultrasound Image-fusion Targeted Biopsies for Prostate Cancer Risk Stratification. European Urology , 75 (5) pp. 733-740. 10.1016/j.eururo.2018.08.007. Green open access
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Han, MK; Criner, GJ; Dransfield, MT; Halpin, DMG; Jones, CE; Kilbride, S; Lange, P; ... Singh, D; + view all (2021) Prognostic value of clinically important deterioration in COPD: IMPACT trial analysis. ERJ Open Research , 7 (1) , Article 00663-2020. 10.1183/23120541.00663-2020. Green open access
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Han, MK; Criner, GJ; Dransfield, MT; Halpin, DMG; Jones, CE; Kilbride, S; Lange, P; ... Martinez, FJ; + view all (2020) The Effect of ICS Withdrawal and Baseline Inhaled Treatment on Exacerbations in the IMPACT Study: A Randomized, Double-blind Multicenter Trial. American Journal of Respiratory and Critical Care Medicine 10.1164/rccm.201912-2478OC. (In press). Green open access
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Hanania, NA; Mannino, DM; Criner, GJ; Dransfield, MT; Han, MK; Jones, CE; Kilbride, S; ... Lipson, DA; + view all (2021) Effect of Age on the Efficacy and Safety of Once-Daily Single-Inhaler Triple Therapy Fluticasone Furoate/Umeclidinium/Vilanterol in Patients With Chronic Obstructive Pulmonary Disease: A Post Hoc Analysis of the IMPACT Trial. Chest , 159 (3) pp. 985-995. 10.1016/j.chest.2020.09.253. Green open access
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Haq, I; Irving, JA; Faull, SV; Dickens, JA; Ordóñez, A; Belorgey, D; Gooptu, B; (2013) Reactive centre loop mutants of α-1-antitrypsin reveal position-specific effects on intermediate formation along the polymerization pathway. Bioscience Reports , 33 (3) , Article e00046. 10.1042/BSR20130038. Green open access
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Haq, I; Irving, JA; Saleh, AD; Dron, L; Regan-Mochrie, GL; Motamedi-Shad, N; Hurst, JR; ... Lomas, DA; + view all (2016) Deficiency Mutations of α1-antitrypsin Differentially Affect Folding, Function and Polymerization. American Journal of Respiratory Cell and Molecular Biology , 54 (1) pp. 71-80. 10.1165/rcmb.2015-0154OC. Green open access
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Hardin, M; Cho, MH; Sharma, S; Glass, K; Castaldi, PJ; McDonald, M-L; Aschard, H; ... COPDGene and Evaluation of COPD Longitudinally to Identify Predi; + view all (2017) Sex-Based Genetic Association Study Identifies CELSR1 as a Possible Chronic Obstructive Pulmonary Disease Risk Locus among Women. American Journal of Respiratory Cell and Molecular Biology , 56 (3) pp. 332-341. 10.1165/rcmb.2016-0172OC. Green open access
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Hartley, B; Criner, GJ; Dransfield, MT; Halpin, DMG; Han, MK; Jones, CE; Kilbride, S; ... Lettis, S; + view all (2019) Misinterpretation of time-to-first event curves can lead to inappropriate treatment. [Letter]. European Respiratory Journal , 54 (3) , Article 1900634. 10.1183/13993003.00634-2019. Green open access
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Hayden, Lystra P; Hobbs, Brian D; Busch, Robert; Cho, Michael H; Liu, Ming; Lopes-Ramos, Camila M; Lomas, David A; ... DeMeo, Dawn L; + view all (2023) X chromosome associations with chronic obstructive pulmonary disease and related phenotypes: an X chromosome-wide association study. Respiratory Research , 24 (1) , Article 38. 10.1186/s12931-023-02337-1. Green open access
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Hobbs, BD; de Jong, K; Lamontagne, M; Bossé, Y; Shrine, N; Artigas, MS; Wain, LV; ... International COPD Genetics Consortium, .; + view all (2017) Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. Nature Genetics , 49 pp. 426-432. 10.1038/ng.3752. Green open access
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Hull, EA; (2015) Antibody Conjugates via Disulfide Bridging: Towards therapeutic and diagnostic applications. Doctoral thesis , UCL (University College London). Green open access
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I

Irving, JA; Haq, I; Dickens, JA; Faull, SV; Lomas, DA; (2014) Altered native stability is the dominant basis for susceptibility of α1-antitrypsin mutants to polymerisation. Biochem J , 460 (1) pp. 103-115. 10.1042/BJ20131650. Green open access
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Irving, JA; Miranda, E; Haq, I; Perez, J; Kotov, VR; Faull, SV; Motamedi-Shad, N; (2015) An antibody raised against a pathogenic serpin variant induces mutant-like behaviour in the wild-type protein. Biochem J , 468 (1) pp. 99-108. 10.1042/BJ20141569. Green open access
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Ishii, T; Angata, T; Wan, ES; Cho, MH; Motegi, T; Gao, C; Ohtsubo, K; ... Kida, K; + view all (2017) Influence of SIGLEC9 polymorphisms on COPD phenotypes including exacerbation frequency. Respirology , 22 (4) pp. 684-690. 10.1111/resp.12952. Green open access
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Ismaila, AS; Risebrough, N; Schroeder, M; Shah, D; Martin, A; Goodall, EC; Ndirangu, K; ... Lomas, DA; + view all (2019) Cost-Effectiveness Of Once-Daily Single-Inhaler Triple Therapy In COPD: The IMPACT Trial. International Journal of Chronic Obstructive Pulmonary Disease , 14 pp. 2681-2695. 10.2147/COPD.S216072. Green open access
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J

Jagger, AM; Waudby, CA; Irving, JA; Christodoulou, J; Lomas, DA; (2020) High-resolution ex vivo NMR spectroscopy of human Z α1-antitrypsin. Nature Communications , 11 , Article 6371. 10.1038/s41467-020-20147-7. Green open access
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K

Kerr, JR; Christian, P; Hodgetts, A; Langford, PR; D Devanur, L; Petty, R; Burke, B; ... Clinical Study Grp; + view all (2007) Current research priorities in chronic fatigue syndrome/myalgic encephalomyelitis: disease mechanisms, a diagnostic test and specific treatments. J CLIN PATHOL , 60 (2) 113 - 116. 10.1136/jcp.2006.042374. Green open access
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Khundakar, AA; Hanson, PS; Erskine, D; Lax, NZ; Roscamp, J; Karyka, E; Tsefou, E; ... Morris, CM; + view all (2016) Analysis of primary visual cortex in dementia with Lewy bodies indicates GABAergic involvement associated with recurrent complex visual hallucinations. Acta Neuropathologica Communications , 4 , Article 66. 10.1186/s40478-016-0334-3. Green open access
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Kinsler, VA; O'Hare, P; Bulstrode, N; Calonje, JE; Chong, WK; Hargrave, D; Jacques, T; ... Slater, O; + view all (2017) Melanoma in congenital melanocytic naevi. British Journal of Dermatology , 176 (5) pp. 1131-1143. 10.1111/bjd.15301. Green open access
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Kruppa, AJ; Ott, S; Chandraratna, DS; Irving, JA; Page, RM; Speretta, E; Seto, T; ... Crowther, DC; + view all (2013) Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease , 1832 (12) 2115 - 2126. 10.1016/j.bbadis.2013.07.019. Green open access
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Kurzawa-Akanbi, M; Keogh, M; Tsefou, E; Ramsay, L; Johnson, M; Keers, S; Ochieng, LWSA; ... Morris, CM; + view all (2020) Neuropathological and biochemical investigation of Hereditary Ferritinopathy cases with ferritin light chain mutation: Prominent protein aggregation in the absence of major mitochondrial or oxidative stress. Neuropathology and Applied Neurobiology 10.1111/nan.12634. Green open access
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L

Laffranchi, M; Berardelli, R; Ronzoni, R; Lomas, DA; Fra, A; (2018) Heteropolymerization of α-1-antitrypsin mutants in cell models mimicking heterozygosity. Human Molecular Genetics , 27 (10) pp. 1785-1793. 10.1093/hmg/ddy090. Green open access
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Laffranchi, M; Elliston, EL; Miranda, E; Perez, J; Ronzoni, R; Jagger, AM; Heyer-Chauhan, N; ... Irving, JA; + view all (2020) Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin. JCI Insight , 5 (14) , Article e135459. 10.1172/jci.insight.135459. Green open access
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Laffranchi, M; Elliston, ELK; Gangemi, F; Berardelli, R; Lomas, DA; Irving, JA; Fra, A; (2019) Characterisation of a type II functionally-deficient variant of alpha-1-antitrypsin discovered in the general population. PLoS One , 14 (1) , Article e0206955. 10.1371/journal.pone.0206955. Green open access
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Lakshman Kumar, P; Wilson, AC; Rocco, A; Cho, MH; Wan, E; Hobbs, BD; Washko, GR; ... McDonald, MLN; + view all (2021) Genetic variation in genes regulating skeletal muscle regeneration and tissue remodelling associated with weight loss in chronic obstructive pulmonary disease. Journal of Cachexia, Sarcopenia and Muscle 10.1002/jcsm.12782. (In press). Green open access
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Lee, ARA; Harvey, E; Sreenan, N; Rossoni, S; Powell, M; Woodcock, A; (2016) Editor's Note. Tropos , 3 (1) pp. 3-4. Green open access
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Leeming, DJ; Byrjalsen, I; Sand, JMB; Bihlet, AR; Lange, P; Evaluation of COPD Longitudinally to Identify Surrogate Endpoint; Thal-Singer, R; ... Vestbo, J; + view all (2017) Biomarkers of collagen turnover are related to annual change in FEV1 in patients with chronic obstructive pulmonary disease within the ECLIPSE study. BMC Pulmonary Medicine , 17 , Article 164. 10.1186/s12890-017-0505-4. Green open access
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Liddle, J; Pearce, AC; Arico-Muendel, C; Belyanskaya, S; Brewster, A; Brown, M; Chung, C-W; ... Lomas, DA; + view all (2021) The development of highly potent and selective small molecule correctors of Z α1-antitrypsin misfolding. Bioorganic & Medicinal Chemistry Letters , 41 , Article 127973. 10.1016/j.bmcl.2021.127973. Green open access
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