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Number of items: 88.
A
Amini, A;
Wiegmann, V;
Patel, H;
Veraitch, F;
Baganz, F;
(2020)
Bioprocess considerations for T cell therapy: Investigating the impact of agitation, dissolved oxygen and pH on T cell expansion and differentiation.
Biotechnology and Bioengineering
, 117
(10)
pp. 3018-3028.
10.1002/bit.27468.
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Arnott, Patrick Marthijn;
(2020)
Development of DNA Nanopores for New Biotherapeutic Applications.
Doctoral thesis (Eng.D), UCL (University College London).
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B
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Bajić, M;
Oberlintner, A;
Kõrge, K;
Likozar, B;
Novak, U;
(2020)
Formulation of active food packaging by design: Linking composition of the film-forming solution to properties of the chitosan-based film by response surface methodology (RSM) modelling.
International Journal of Biological Macromolecules
, 160
pp. 971-978.
10.1016/j.ijbiomac.2020.05.186.
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Beal, J;
Farny, NG;
Haddock-Angelli, T;
Selvarajah, V;
Baldwin, GS;
Buckley-Taylor, R;
Gershater, M;
... Simona, MF; + view all
(2020)
Robust estimation of bacterial cell count from optical density.
Communications Biology
, 3
, Article 512. 10.1038/s42003-020-01127-5.
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Beal, J;
Goñi-Moreno, A;
Myers, C;
Hecht, A;
De Vicente, MDC;
Parco, M;
Schmidt, M;
... Porcar, M; + view all
(2020)
The long journey towards standards for engineering biosystems: Are the Molecular Biology and the Biotech communities ready to standardise?
EMBO Reports
, 21
(5)
, Article e50521. 10.15252/embr.202050521.
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Bhatta, Mihir;
Dutta, Nalok;
Nandi, Srijita;
Dutta, Shanta;
Saha, Malay Kumar;
(2020)
Mother-to-child HIV transmission and its correlates in India: systematic review and meta-analysis.
BMC Pregnancy Childbirth
, 20
(1)
, Article 509. 10.1186/s12884-020-03193-3.
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C
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Chauhan, VM;
Zhang, H;
Dalby, PA;
Aylott, JW;
(2020)
Advancements in the co-formulation of biologic therapeutics.
Journal of Controlled Release
, 327
pp. 397-405.
10.1016/j.jconrel.2020.08.013.
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Clark, Colleen E.;
(2020)
Characterization and Scalability Assessment of a Parallel Single-Use Bioreactor System for Mammalian Cell Culture.
Doctoral thesis (Ph.D), UCL (University College London).
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Colant, N;
Melinek, B;
Teneb, J;
Goldrick, S;
Rosenberg, W;
Frank, S;
Bracewell, DG;
(2020)
A rational approach to improving titer in Escherichia coli‐based cell‐free protein synthesis reactions.
Biotechnology Progress
, Article e3062. 10.1002/btpr.3062.
(In press).
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Colin, P-Y;
Dalby, PA;
(2020)
Functional and computational identification of a rescue mutation near the active site of an mRNA methyltransferase.
Scientific Reports
, 10
, Article 21841. 10.1038/s41598-020-79026-2.
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Colombo, B;
Pereira, J;
Martins, M;
Torres-Acosta, MA;
Dias, ACR;
Lemos, PC;
Ventura, SPM;
... Serafim, LS; + view all
(2020)
Recovering PHA from mixed microbial biomass: Using non-ionic surfactants as a pretreatment step.
Separation and Purification Technology
, 253
, Article 117521. 10.1016/j.seppur.2020.117521.
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Cornish, E;
Filipovic, I;
Åsenius, F;
Williams, D;
McDonnell, T;
(2020)
Innate immune responses to acute viral infection during pregnancy.
Frontiers in Immunology
10.3389/fimmu.2020.572567.
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Costariol, E;
Rotondi, MC;
Amini, A;
Hewitt, CJ;
Nienow, AW;
Heathman, TRJ;
Rafiq, QA;
(2020)
Demonstrating the Manufacture of Human CAR-T Cells in an Automated Stirred-Tank Bioreactor.
Biotechnology Journal
, 15
(9)
, Article 2000177. 10.1002/biot.202000177.
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D
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Dobrijevic, D;
Nematollahi, LA;
Hailes, HC;
Ward, JM;
(2020)
pET expression vector customized for efficient seamless cloning.
Biotechniques
10.2144/btn-2020-0101.
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Durán-Jiménez, G;
Stevens, LA;
Kostas, ET;
Hernández-Montoya, V;
Robinson, JP;
Binner, ER;
(2020)
Rapid, simple and sustainable synthesis of ultra-microporous carbons with high performance for CO2 uptake, via microwave heating.
Chemical Engineering Journal
, 388
, Article 124309. 10.1016/j.cej.2020.124309.
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Duran-Villalobos, CA;
Goldrick, S;
Lennox, B;
(2020)
Multivariate statistical process control of an industrial-scale fed-batch simulator.
Computers and Chemical Engineering
, 132
, Article 106620. 10.1016/j.compchemeng.2019.106620.
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E
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Elgabry, M;
Nesbeth, D;
Johnson, SD;
(2020)
A Systematic Review of the Criminogenic Potential of Synthetic Biology and Routes to Future Crime Prevention.
Frontiers in Bioengineering and Biotechnology
, 8
, Article 571672. 10.3389/fbioe.2020.571672.
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Elgabry, M;
Nesbeth, D;
Johnson, SD;
(2020)
A systematic review protocol for crime trends facilitated by synthetic biology.
Systematic Reviews
, 9
, Article 22. 10.1186/s13643-020-1284-1.
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F
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Farid, SS;
Baron, M;
Stamatis, C;
Nie, W;
Coffman, J;
(2020)
Benchmarking biopharmaceutical process development and manufacturing cost contributions to R&D.
mAbs
, 12
(1)
, Article 1754999. 10.1080/19420862.2020.1754999.
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Farinha, F;
Pepper, RJ;
Oliveira, DG;
McDonnell, T;
Isenberg, DA;
Rahman, A;
(2020)
Outcomes of membranous and proliferative lupus nephritis – analysis of a single-centre cohort with more than 30 years of follow-up.
Rheumatology
10.1093/rheumatology/keaa103.
(In press).
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Fernadez-Cerezo, L;
Rayat, A;
Chatel, A;
Pollard, J;
Lye, G;
Hoare, M;
(2020)
The prediction of the operating conditions on the permeate flux and on protein aggregation during membrane processing of monoclonal antibodies.
Journal of Membrane Science
, 596
, Article 117606. 10.1016/j.memsci.2019.117606.
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Fischer, Vivien;
(2020)
Rapid optimisation of preparative chromatography for monoclonal antibody purification using high-throughput methodology.
Doctoral thesis (Eng.D), UCL (University College London).
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G
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Goldrick, S;
Sandner, V;
Cheeks, M;
Turner, R;
Farid, SS;
McCreath, G;
Glassey, J;
(2020)
Multivariate Data Analysis Methodology to Solve Data Challenges Related to Scale-up Model Validation and Missing Data on a Micro-Bioreactor System.
Biotechnology Journal
, 15
(3)
, Article e1800684. 10.1002/biot.201800684.
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Goldrick, S;
Umprecht, A;
Tang, A;
Zakrzewski, R;
Cheeks, M;
Turner, R;
Charles, A;
... Farid, SS; + view all
(2020)
High-Throughput Raman Spectroscopy Combined with Innovate Data Analysis Workflow to Enhance Biopharmaceutical Process Development.
Processes
, 8
(9)
, Article 1179. 10.3390/pr8091179.
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Gustafsson, K;
Herrmann, T;
Dieli, F;
(2020)
Editorial: Understanding Gamma Delta T Cell Multifunctionality - Towards Immunotherapeutic Applications.
Frontiers in Immunology
, 11
, Article 921. 10.3389/fimmu.2020.00921.
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H
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Hanga, Mariana P;
Ali, Junaid;
Moutsatsou, Panagiota;
de la Raga, Fritz A;
Hewitt, Christopher J;
Nienow, Alvin;
Wall, Ivan;
(2020)
Bioprocess development for scalable production of cultivated meat.
Biotechnology and Bioengineering
, 117
(10)
pp. 3029-3039.
10.1002/bit.27469.
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Henríquez, M-J;
Braun-Galleani, S;
Nesbeth, D;
(2020)
Whole cell biosynthetic activity of Komagataella phaffii (Pichia pastoris) GS115 strains engineered with transgenes encoding Chromobacterium violaceum ω-transaminase alone or combined with native transketolase.
Biotechnology Progress
, 36
(1)
, Article e2893. 10.1002/btpr.2893.
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Henríquez, MJ;
Cardós-Elena, RP;
Nesbeth, D;
(2020)
Genomic data mining reveals the transaminase repertoire of Komagataella phaffii (Pichia pastoris) strain GS115 and supports a systematic nomenclature.
Journal of Genetics
, 99
, Article 49. 10.1007/s12041-020-01201-1.
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Hickman, Thomas William Paul;
(2020)
The development of a novel, CoA-dependent, organic acid modification system as a link to a biosynthetic pathway for the nylon 6 monomer, 6-aminocaproic acid.
Doctoral thesis (Ph.D), UCL (University College London).
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Hickman, TWP;
Baud, D;
Benhamou, L;
Hailes, HC;
Ward, JM;
(2020)
Characterisation of four hotdog-fold thioesterases for their implementation in a novel organic acid production system.
Applied Microbiology and Biotechnology
, 104
pp. 4397-4406.
10.1007/s00253-020-10519-w.
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J
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Johnson, TF;
Iacoviello, F;
Hayden, DJ;
Welsh, JH;
Levison, PR;
Shearing, PR;
Bracewell, DG;
(2020)
Packed bed compression visualisation and flow simulation using an erosion-dilation approach.
Journal of Chromatography A
, 1611
, Article 460601. 10.1016/j.chroma.2019.460601.
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Joshi, Jay Ketan Kong;
(2020)
The development of next-generation small volume biophysical screening for the early assessment of monoclonal antibody manufacturability.
Doctoral thesis (Ph.D), UCL (University College London).
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Juodeikis, R;
Lee, MJ;
Mayer, M;
Mantell, J;
Brown, IR;
Verkade, P;
Woolfson, DN;
... Warren, MJ; + view all
(2020)
Effect of metabolosome encapsulation peptides on enzyme activity, coaggregation, incorporation, and bacterial microcompartment formation.
MicrobiologyOpen
, 9
(5)
, Article e1010. 10.1002/mbo3.1010.
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K
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Kamrad, S;
Grossbach, J;
Rodríguez-López, M;
Mülleder, M;
Townsend, S;
Cappelletti, V;
Stojanovski, G;
... Bähler, J; + view all
(2020)
Pyruvate kinase variant of fission yeast tunes carbon metabolism, cell regulation, growth and stress resistance.
Molecular Systems Biology
, 16
(4)
, Article e9270. 10.15252/msb.20199270.
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Kina-Ysa, M;
Flores-Fernández, CN;
Flores-Santos, JC;
Zavaleta, AI;
(2020)
Obtención de hidrolizados proteicos de leguminosas usando una proteasa recombinante de Pseudomonas aeruginosa M211 = Obtaining protein hydrolysates from leguminous using a recombinant protease from Pseudomonas aeruginosa M211.
Revista chilena de nutrición
, 47
(3)
pp. 381-389.
10.4067/S0717-75182020000300381.
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Kõrge, K;
Bajić, M;
Likozar, B;
Novak, U;
(2020)
Active chitosan–chestnut extract films used for packaging and storage of fresh pasta.
International Journal of Food Science & Technology
, 55
(8)
pp. 3043-3052.
10.1111/ijfs.14569.
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Kõrge, K;
Šeme, H;
Bajić, M;
Likozar, B;
Novak, U;
(2020)
Reduction in Spoilage Microbiota and Cyclopiazonic Acid Mycotoxin with Chestnut Extract Enriched Chitosan Packaging: Stability of Inoculated Gouda Cheese.
Foods
, 9
(11)
, Article 1645. 10.3390/foods9111645.
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Kostas, ET;
Durán-Jiménez, G;
Shepherd, BJ;
Meredith, W;
Stevens, LA;
Williams, OSA;
Lye, GJ;
(2020)
Microwave pyrolysis of olive pomace for bio-oil and bio-char production.
Chemical Engineering Journal
, 387
, Article 123404. 10.1016/j.cej.2019.123404.
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Kostas, ET;
White, DA;
Cook, DJ;
(2020)
Bioethanol Production from UK Seaweeds: Investigating Variable Pre-treatment and Enzyme Hydrolysis Parameters.
BioEnergy Research
, 13
pp. 271-285.
10.1007/s12155-019-10054-1.
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L
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Lanphere, C;
Arnott, PM;
Jones, SF;
Korlova, K;
Howorka, S;
(2020)
A Biomimetic DNA-Based Membrane Gate for Protein-Controlled Transport of Cytotoxic Drugs.
Angewandte Chemie International Edition
10.1002/anie.202011583.
(In press).
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Li, Y;
Ducci, A;
Micheletti, M;
(2020)
Study on mixing characteristics in shaken microwell systems.
Biochemical Engineering Journal
, 153
, Article 107392. 10.1016/j.bej.2019.107392.
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Li, Yi;
(2020)
Free surface, flow and mixing characterisation in orbitally shaken reactors.
Doctoral thesis (Ph.D), UCL (University College London).
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Lu, X;
Yao, Y;
Yang, Y;
Zhang, Z;
Gu, J;
Mojovic, L;
Knezevic-Jugovic, Z;
... Hao, J; + view all
(2020)
Ethylene glycol and glycolic acid production by wild-type Escherichia coli.
Biotechnology and Applied Biochemistry
, 68
(4)
pp. 744-755.
10.1002/bab.1987.
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Lu, Yang;
(2020)
Design and optimisation of operon constructs for expression and characterisation of Class I cytochrome P450s from actinomycetes.
Doctoral thesis (Ph.D), UCL (University College London).
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Lularevic, Maximilian;
(2020)
A combined mathematical and experimental investigation of lactate metabolism in industrial CHO cell cultures.
Doctoral thesis (Eng.D), UCL (University College London).
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M
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Malcı, K;
Walls, LE;
Rios-Solis, L;
(2020)
Multiplex Genome Engineering Methods for Yeast Cell Factory Development.
Frontiers in Bioengineering and Biotechnology
, 8
, Article 589468. 10.3389/fbioe.2020.589468.
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Martinez, M;
Mannall, G;
Spitali, M;
Norrant, EL;
Bracewell, DG;
(2020)
Reactor Design for Continuous Monoclonal Antibody Precipitation Based Upon Micro‐mixing.
Journal of Chemical Technology & Biotechnology
10.1002/jctb.6652.
(In press).
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Mota Pacheco, Luis Erick;
(2020)
Biocatalytic conversion of renewable feedstocks for production of value-added chemicals.
Doctoral thesis (Ph.D), UCL (University College London).
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N
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Novak, U;
Bajić, M;
Kõrge, K;
Oberlintner, A;
Murn, J;
Lokar, K;
Triler, KV;
(2020)
From waste/residual marine biomass to active biopolymer-based packaging film materials for food industry applications- A review.
Physical Sciences Reviews
, 5
(3)
, Article 20190099. 10.1515/psr-2019-0099.
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Nowrouzi, B;
Li, RA;
Walls, LE;
D'Espaux, L;
Malcı, K;
Liang, L;
Jonguitud-Borrego, N;
... Rios-Solis, L; + view all
(2020)
Enhanced production of taxadiene in Saccharomyces cerevisiae.
Microbial Cell Factories
, 19
, Article 200. 10.1186/s12934-020-01458-2.
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P
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Papachristodoulou, M;
Doutch, J;
Leung, HSB;
Church, A;
Charleston, T;
Clifton, LA;
Butler, PD;
... Bracewell, DG; + view all
(2020)
In situ neutron scattering of antibody adsorption during protein A chromatography.
Journal of Chromatography A
, 1617
, Article 460842. 10.1016/j.chroma.2019.460842.
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Papachristodoulou, Maria;
(2020)
Neutron scattering to characterise protein interactions with solid-liquid interfaces in bioprocessing.
Doctoral thesis (Ph.D), UCL (University College London).
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Papathanasiou, MM;
Stamatis, C;
Lakelin, M;
Farid, S;
Titchener-Hooker, N;
Shah, N;
(2020)
Autologous CAR T-cell therapies supply chain: challenges and opportunities?
Cancer Gene Therapy
10.1038/s41417-019-0157-z.
(In press).
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Patel, N;
Farid, S;
Morris, S;
(2020)
How should we evaluate the cost-effectiveness of CAR T-cell therapies?
Health Policy and Technology
10.1016/j.hlpt.2020.03.002.
(In press).
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Pereira Chilima, TD;
Moncaubeig, F;
Farid, SS;
(2020)
Estimating capital investment and facility footprint in cell therapy facilities.
Biochemical Engineering Journal
, 155
, Article 107439. 10.1016/j.bej.2019.107439.
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Peticone, C;
Thompson, DDS;
Dimov, N;
Jevans, B;
Glass, N;
Micheletti, M;
Knowles, JC;
... Wall, IB; + view all
(2020)
Characterisation of osteogenic and vascular responses of hMSCs to Ti-Co doped phosphate glass microspheres using a microfluidic perfusion platform.
Journal of Tissue Engineering
, 11
pp. 1-19.
10.1177/2041731420954712.
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R
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Roddan, R;
Sula, A;
Méndez-Sánchez, D;
Subrizi, F;
Lichman, BR;
Broomfield, J;
Richter, M;
... Hailes, HC; + view all
(2020)
Single step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases.
Communications Chemistry
, 3
(1)
10.1038/s42004-020-00416-8.
(In press).
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Roddan, R;
Ward, JM;
Keep, NH;
Hailes, HC;
(2020)
Pictet–Spenglerases in alkaloid biosynthesis: Future applications in biocatalysis.
Current Opinion in Chemical Biology
, 55
pp. 69-76.
10.1016/j.cbpa.2019.12.003.
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S
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Samaras, JJ;
Ducci, A;
Micheletti, M;
(2020)
Flow, suspension and mixing dynamics in DASGIP bioreactors, Part 2.
AIChE Journal
, 66
(11)
, Article e16999. 10.1002/aic.16999.
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Samaras, JJ;
Micheletti, M;
Ducci, A;
(2020)
Flow, suspension, and mixing dynamics in DASGIP bioreactors: Part 1.
AIChE Journal
10.1002/aic.17014.
(In press).
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Santos, M;
O'Sullivan, B;
Müller, S;
Bunescu, A;
Baganz, F;
Marques, MPC;
Hailes, H;
... Wohlgemuth, R; + view all
(2020)
Chemoenzymatic microfluidic cascade reaction: Coupling of a diels-alder reaction with a transketolase-catalyzed reaction.
In:
MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences.
(pp. pp. 693-694).
CBMS: Online conference.
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Sawant, N;
Kaur, K;
Holland, DA;
Hickey, JM;
Agarwal, S;
Brady, JR;
Dalvie, NC;
... Volkin, DB; + view all
(2020)
Rapid Developability Assessments to Formulate Recombinant Protein Antigens as Stable, Low-Cost, Multi-Dose Vaccine Candidates: Case-Study With Non-Replicating Rotavirus (NRRV) Vaccine Antigens.
Journal of Pharmaceutical Sciences
10.1016/j.xphs.2020.11.039.
(In press).
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Silva Couto, P;
Rotondi, MC;
Bersenev, A;
Hewitt, CJ;
Nienow, AW;
Verter, F;
Rafiq, QA;
(2020)
Expansion of human mesenchymal stem/stromal cells (hMSCs) in bioreactors using microcarriers: lessons learnt and what the future holds.
Biotechnology Advances
, 45
, Article 107636. 10.1016/j.biotechadv.2020.107636.
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Song, Zhongdi;
(2020)
Optimisation of Phaeodactylum tricornutum as a microalgal expression host for industrial biotechnology.
Doctoral thesis (Ph.D), UCL (University College London).
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Song, Z;
Lye, GJ;
Parker, BM;
(2020)
Morphological and biochemical changes in Phaeodactylum tricornutum triggered by culture media: Implications for industrial exploitation.
Algal Research
, 47
, Article 101822. 10.1016/j.algal.2020.101822.
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Spice, AJ;
Aw, R;
Bracewell, DG;
Polizzi, KM;
(2020)
Improving the reaction mix of a Pichia pastoris cell-free system using a design of experiments approach to minimise experimental effort.
Synthetic and Systems Biotechnology
, 5
(3)
pp. 137-144.
10.1016/j.synbio.2020.06.003.
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Spice, AJ;
Aw, R;
Bracewell, DG;
Polizzi, KM;
(2020)
Synthesis and Assembly of Hepatitis B Virus-Like Particles in a Pichia pastoris Cell-Free System.
Frontiers in Bioengineering and Biotechnology
, 8
, Article 72. 10.3389/fbioe.2020.00072.
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Stojanovski, G;
Dobrijevic, D;
Hailes, HC;
Ward, JM;
(2020)
Identification and catalytic properties of new epoxide hydrolases from the genomic data of soil bacteria.
Enzyme and Microbial Technology
, 139
, Article 109592. 10.1016/j.enzmictec.2020.109592.
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T
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Tan, R;
Franzreb, M;
(2020)
Continuous ultrafiltration/diafiltration using a 3D‐printed two membrane single pass module.
Biotechnology and Bioengineering
, 117
(3)
pp. 654-661.
10.1002/bit.27233.
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Torres‐Acosta, MA;
González‐Mora, A;
Ruiz‐Ruiz, F;
Rito‐Palomares, M;
Benavides, J;
(2020)
Economic Evaluation of M13 Bacteriophage Production at Large‐Scale for Therapeutic Applications using Aqueous Two‐Phase Systems.
Journal of Chemical Technology & Biotechnology
, 95
(11)
pp. 2822-2833.
10.1002/jctb.6526.
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V
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Velez-Suberbie, ML;
Morris, SA;
Kaur, K;
Hickey, JM;
Joshi, SB;
Volkin, DB;
Bracewell, DG;
(2020)
Holistic process development to mitigate proteolysis of a subunit rotavirus vaccine candidate produced in Pichia pastoris by means of an acid pH pulse during fed‐batch fermentation.
Biotechnology Progress
, 36
(3)
, Article e2966. 10.1002/btpr.2966.
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W
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Walls, LE;
Rios-Solis, L;
(2020)
Sustainable Production of Microbial Isoprenoid Derived Advanced Biojet Fuels Using Different Generation Feedstocks: A Review.
Frontiers in Bioengineering and Biotechnology
, 8
, Article 599560. 10.3389/fbioe.2020.599560.
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Wang, Y;
Gu, J;
Lu, X;
Zhang, Z;
Yang, Y;
Sun, S;
Kostas, ET;
... Hao, J; + view all
(2020)
2,3-Dihydroxyisovalerate production by Klebsiella pneumoniae.
Applied Microbiology and Biotechnology
, 104
pp. 6601-6613.
10.1007/s00253-020-10711-y.
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Watkins, H;
Robinson, JM;
Breed, MF;
Parker, B;
Weinstein, P;
(2020)
Microbiome-Inspired Green Infrastructure: A Toolkit for Multidisciplinary Landscape Design.
Trends in Biotechnology
, 38
(12)
pp. 1305-1308.
10.1016/j.tibtech.2020.04.009.
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Wei, X;
Hellier, P;
Baganz, F;
(2020)
Impact on performance and emissions of the aspiration of algal biomass suspensions in the intake air of a direct injection diesel engine.
Energy Conversion and Management
, 205
, Article 112347. 10.1016/j.enconman.2019.112347.
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Wei, Xinyu;
(2020)
Evaluating alternative routes of using algal biomass for energy production.
Doctoral thesis (Ph.D), UCL (University College London).
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Wiegmann, V;
Martinez, CB;
Baganz, F;
(2020)
Using a Parallel Micro-Cultivation System (Micro-Matrix) as a Process Development Tool for Cell Culture Applications.
Animal Cell Biotechnology
, 2095
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