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Number of items: 113.
Article
Alliouachene, S;
Bilanges, B;
Chicanne, G;
Anderson, KE;
Pearce, W;
Ali, K;
Valet, C;
... Vanhaesebroeck, B; + view all
(2015)
Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity.
Cell Reports
, 13
(9)
pp. 1881-1894.
10.1016/j.celrep.2015.10.052.
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Altshuler, DM;
Durbin, RM;
Abecasis, GR;
Bentley, DR;
Chakravarti, A;
Clark, AG;
Donnelly, P;
... Abecasis, GR; + view all
(2015)
A global reference for human genetic variation.
NATURE
, 526
(7571)
68-+.
10.1038/nature15393.
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Amary, MF;
Ye, H;
Forbes, G;
Damato, S;
Maggiani, F;
Pollock, R;
Tirabosco, R;
(2015)
Isocitrate dehydrogenase 1 mutations (IDH1) and p16/CDKN2A copy number change in conventional chondrosarcomas.
Virchows Arch
, 466
(2)
217 - 222.
10.1007/s00428-014-1685-4.
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Amelina, H;
Subramaniam, S;
Moiseeva, V;
Armstrong, CA;
Pearson, SR;
Tomita, K;
(2015)
Telomere protein Rap1 is a charge resistant scaffolding protein in chromosomal bouquet formation.
BMC Biol
, 13
(1)
, Article 37. 10.1186/s12915-015-0149-x.
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Artim-Esen, B;
Pericleous, C;
Mackie, I;
Ripoll, VM;
Latchman, D;
Isenberg, D;
Rahman, A;
... Giles, I; + view all
(2015)
Anti-factor Xa antibodies in patients with antiphospholipid syndrome and their effects upon coagulation assays.
Arthritis Research & Therapy
, 17
, Article 47. 10.1186/s13075-015-0568-7.
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Arya, M;
Thrasivoulou, C;
Henrique, R;
Millar, M;
Hamblin, R;
Davda, R;
Aare, K;
... Ahmed, A; + view all
(2015)
Targets of Wnt/ß-catenin transcription in penile carcinoma.
PLoS One
, 10
(4)
, Article e0124395. 10.1371/journal.pone.0124395.
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Badar, A;
Kiru, L;
Kalber, TL;
Jathoul, A;
Straathof, K;
Årstad, E;
Lythgoe, MF;
(2015)
Fluorescence-guided development of a tricistronic vector encoding bimodal optical and nuclear genetic reporters for in vivo cellular imaging.
EJNMMI Res
, 5
, Article 18. 10.1186/s13550-015-0097-z.
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Bandula, S;
Punwani, S;
Rosenberg, WM;
Jalan, R;
Hall, AR;
Dhillon, A;
Moon, JC;
(2015)
Equilibrium Contrast-enhanced CT Imaging to Evaluate Hepatic Fibrosis: Initial Validation by Comparison with Histopathologic Sampling.
Radiology
, 275
(1)
136 - 143.
10.1148/radiol.14141435.
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Beavan, M;
McNeill, A;
Proukakis, C;
Hughes, DA;
Mehta, A;
Schapira, AH;
(2015)
Evolution of prodromal clinical markers of Parkinson disease in a GBA mutation-positive cohort.
JAMA Neurol
, 72
(2)
201 - 208.
10.1001/jamaneurol.2014.2950.
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Billen, A;
Madrigal, JA;
Strydom, A;
Szydlo, RM;
Switzer, GE;
Shaw, BE;
(2015)
Predonation Health-Related Quality of Life Scores Predict Time to Recovery in Hematopoietic Stem Cell Donors.
Biology of Blood and Marrow Transplantation
, 21
(2)
pp. 350-356.
10.1016/j.bbmt.2014.10.028.
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Bitton, DA;
Atkinson, SR;
Rallis, C;
Smith, GC;
Ellis, DA;
Chen, Y;
Malecki, M;
... Bahler, J; + view all
(2015)
Widespread exon skipping triggers degradation by nuclear RNA surveillance in fission yeast.
Genome Research
, 25
(6)
pp. 884-896.
10.1101/gr.185371.114.
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Bogaerts, J;
Sydes, MR;
Keat, N;
McConnell, A;
Benson, A;
Ho, A;
Roth, A;
... Seymour, M; + view all
(2015)
Clinical trial designs for rare diseases: studies developed and discussed by the International Rare Cancers Initiative.
Eur J Cancer
, 51
(3)
pp. 271-281.
10.1016/j.ejca.2014.10.027.
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Butcher, LM;
Beck, S;
(2015)
Probe Lasso: a novel method to rope in differentially methylated regions with 450K DNA methylation data.
Methods
, 72
21 - 28.
10.1016/j.ymeth.2014.10.036.
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Cattin, AL;
Burden, JJ;
Van Emmenis, L;
Mackenzie, FE;
Hoving, JJ;
Garcia Calavia, N;
Guo, Y;
... Lloyd, AC; + view all
(2015)
Macrophage-Induced Blood Vessels Guide Schwann Cell-Mediated Regeneration of Peripheral Nerves.
Cell
, 162
(5)
pp. 1127-1139.
10.1016/j.cell.2015.07.021.
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Church, DM;
Schneider, VA;
Steinberg, K;
Schatz, MC;
Quinlan, AR;
Chin, C-S;
Kitts, PA;
... Flicek, P; + view all
(2015)
Extending reference assembly models.
Genome Biology
, 16
(1)
, Article 13. 10.1186/s13059-015-0587-3.
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Cohen, H;
Doré, CJ;
Clawson, S;
Hunt, BJ;
Isenberg, D;
Khamashta, M;
Muirhead, N;
(2015)
Rivaroxaban in antiphospholipid syndrome (RAPS) protocol: a prospective, randomized controlled phase II/III clinical trial of rivaroxaban versus warfarin in patients with thrombotic antiphospholipid syndrome, with or without SLE.
Lupus
, 24
(10)
pp. 1087-1094.
10.1177/0961203315581207.
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Cohen, H;
Hunt, B;
Efythymiou, M;
Arachchillage, D;
Ruiz, M;
Clawson, S;
Muirhead, N;
... Collaborators, RAPST; + view all
(2015)
Raps (rivaroxaban in antiphospholipid syndrome): a prospective randomised controlled phase II/III clinical trial of rivaroxaban vs. warfarin in patients with thrombotic antiphospholipid syndrome, with or without SLE.
Journal of Thrombosis and Haemostasis
, 13
, Article LB003. DOI: 10.1111/jth.12993.
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Cook, R;
Zoumpoulidou, G;
Luczynski, MT;
Rieger, S;
Moquet, J;
Spanswick, VJ;
Hartley, JA;
... Mittnacht, S; + view all
(2015)
Direct Involvement of Retinoblastoma Family Proteins in DNA Repair by Non-homologous End-Joining.
Cell Rep
, 10
(12)
2006 - 2018.
10.1016/j.celrep.2015.02.059.
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Dabrowska, A;
Venero, JL;
Iwasawa, R;
Hankir, MK;
Rahman, S;
Boobis, A;
Hajji, N;
(2015)
PGC-1α controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity.
Aging (Albany NY)
, 7
(9)
pp. 629-647.
10.18632/aging.100790.
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Denas, O;
Sandstrom, R;
Cheng, Y;
Beal, K;
Herrero, J;
Hardison, RC;
Taylor, J;
(2015)
Genome-wide comparative analysis reveals human-mouse regulatory landscape and evolution.
BMC Genomics
, 16
, Article 87. 10.1186/s12864-015-1245-6.
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Dickson, GJ;
Bustraan, S;
Hills, RK;
Ali, A;
Goldstone, AH;
Burnett, AK;
Linch, DC;
(2015)
The value of molecular stratification for CEBPA_DM and NPM1_MUT_FLT3_WT genotypes in older patients with acute myeloid leukaemia.
British Journal of Haematology
10.1111/bjh.13873.
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Ecker, S;
Pancaldi, V;
Rico, D;
Valencia, A;
(2015)
Higher gene expression variability in the more aggressive subtype of chronic lymphocytic leukemia.
Genome Medicine
, 7
, Article 8. 10.1186/s13073-014-0125-z.
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Feber, A;
Arya, M;
De Winter, P;
Saqib, M;
Nigam, R;
Malone, PR;
Tan, WS;
... Kelly, JD; + view all
(2015)
Epigenetics Markers of Metastasis and HPV-Induced Tumorigenesis in Penile Cancer.
Clinical Cancer Research
, 21
(5)
pp. 1196-1206.
10.1158/1078-0432.CCR-14-1656.
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Fennell, A;
Fernández-Álvarez, A;
Tomita, K;
Cooper, JP;
(2015)
Telomeres and centromeres have interchangeable roles in promoting meiotic spindle formation.
Journal of Cell Biology
, 208
(4)
pp. 415-428.
10.1083/jcb.201409058.
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Field, N;
Lechner, M;
(2015)
Exploring the implications of HPV infection for head and neck cancer.
Sexually Transmitted Infections
, 91
(4)
pp. 229-230.
10.1136/sextrans-2014-051808.
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Furniss, D;
Masci, P;
Curzon, P;
Mayer, A;
Blandford, A;
(2015)
Exploring medical device design and use through layers of Distributed Cognition: How a glucometer is coupled with its context.
Journal of Biomedical Informatics
, 53
pp. 330-341.
10.1016/j.jbi.2014.12.006.
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Futter, CE;
Tomas, A;
Vaughan, SO;
Burgoyne, T;
Sorkin, A;
Hochhauser, D;
(2015)
WASH and Tsg101/ALIX-dependent diversion of stress-internalised EGFR from the canonical endocytic pathway.
Nature Communications
, 6
, Article 7324. 10.1038/ncomms8324.
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Gale, RE;
Tawana, K;
Wang, J;
Renneville, A;
Bodor, C;
Hills, R;
Loveday, C;
... Fitzgibbon, J; + view all
(2015)
Disease evolution and outcomes in familial AML with germline CEBPA mutations.
Blood
, 126
(10)
pp. 1214-1223.
10.1182/blood-2015-05-647172.
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Gale, RE;
Lamb, K;
Allen, C;
El-Sharkawi, D;
Stowe, C;
Jenkinson, S;
Tinsley, S;
... Linch, DC; + view all
(2015)
Simpson's Paradox and the Impact of Different DNMT3A Mutations on Outcome in Younger Adults With Acute Myeloid Leukemia.
Journal of Clinical Oncology
, 33
(18)
pp. 2072-2083.
10.1200/JCO.2014.59.2022.
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Galluzzi, L;
Bravo-San Pedro, JM;
Vitale, I;
Aaronson, SA;
Abrams, JM;
Adam, D;
Alnemri, ES;
... Kroemer, G; + view all
(2015)
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.
Cell Death and Differentiation
, 22
(1)
pp. 58-73.
10.1038/cdd.2014.137.
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Ghorashian, S;
Veliça, P;
Chua, I;
McNicol, AM;
Carpenter, B;
Holler, A;
Nicholson, E;
... Stauss, HJ; + view all
(2015)
CD8 T cell tolerance to a tumor-associated self-antigen is reversed by CD4 T cells engineered to express the same T cell receptor.
Journal of Immunology
, 194
(3)
1080 - 1089.
10.4049/jimmunol.1401703.
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Goldstein, R;
Sosabowski, J;
Livanos, M;
Leyton, J;
Vigor, K;
Bhavsar, G;
Nagy-Davidescu, G;
... Chester, K; + view all
(2015)
Development of the designed ankyrin repeat protein (DARPin) G3 for HER2 molecular imaging.
Eur J Nucl Med Mol Imaging
, 42
(2)
288 - 301.
10.1007/s00259-014-2940-2.
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Gonçalves, MR;
Johnson, SP;
Ramasawmy, R;
Pedley, RB;
Lythgoe, MF;
Walker-Samuel, S;
(2015)
Decomposition of spontaneous fluctuations in tumour oxygenation using BOLD MRI and independent component analysis.
British Journal of Cancer
, 113
(8)
pp. 1168-1177.
10.1038/bjc.2015.270.
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Gonzalez Malagon, SG;
Melidoni, AN;
Hernandez, D;
Omar, BA;
Houseman, L;
Veeravalli, S;
Scott, F;
... Shephard, EA; + view all
(2015)
The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing.
Biochemical Pharmacology
, 96
(3)
pp. 267-277.
10.1016/j.bcp.2015.05.013.
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Gravells, P;
Ahrabi, S;
Vangala, RK;
Tomita, K;
Brash, JT;
Brustle, LA;
Chung, C;
... Porter, AC; + view all
(2015)
Use of the HPRT gene to study nuclease-induced DNA double-strand break repair.
Human Molecular Genetics
, 24
(24)
pp. 7097-7110.
10.1093/hmg/ddv409.
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Guggenheim, JA;
Allen, TJ;
Plumb, A;
Zhang, EZ;
Rodriguez-Justo, M;
Punwani, S;
Beard, PC;
(2015)
Photoacoustic imaging of human lymph nodes with endogenous lipid and hemoglobin contrast.
Journal of Biomedical Optics
, 20
(5)
050504.
10.1117/1.JBO.20.5.050504.
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Guillermet-Guibert, J;
Smith, LB;
Halet, G;
Whitehead, MA;
Pearce, W;
Rebourcet, D;
León, K;
... Vanhaesebroeck, B; + view all
(2015)
Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells.
PLoS Genetics
, 11
(7)
, Article e1005304. 10.1371/journal.pgen.1005304.
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Hamilton, NJ;
Kanani, M;
Roebuck, DJ;
Hewitt, RJ;
Cetto, R;
Culme-Seymour, EJ;
Toll, E;
... Birchall, MA; + view all
(2015)
Tissue-engineered tracheal replacement in a child: a 4-year follow-up study.
Am J Transplant
, 15
(10)
pp. 2750-2757.
10.1111/ajt.13318.
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Henderson, S;
Fenton, T;
(2015)
APOBEC3 genes: retroviral restriction factors to cancer drivers.
Trends in Molecular Medicine
, 21
(5)
pp. 274-284.
10.1016/j.molmed.2015.02.007.
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Jenkinson, S;
Kirkwood, AA;
Goulden, N;
Vora, A;
Linch, DC;
Gale, RE;
(2015)
Impact of PTEN abnormalities on outcome in pediatric patients with T-cell acute lymphoblastic leukemia treated on the MRC UKALL2003 trial.
Leukemia
10.1038/leu.2015.206.
(In press).
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Kalimuthu, SN;
Tilley, C;
Forbes, G;
Ye, H;
Lehovsky, K;
Pillay, N;
Seddon, BM;
... Flanagan, AM; + view all
(2015)
Clinical outcome in patients with peripherally-sited atypical lipomatous tumours and dedifferentiated liposarcoma.
The Journal of Pathology: Clinical Research
, 1
(2)
pp. 106-112.
10.1002/cjp2.12.
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Khan, I;
Morris, S;
Hackshaw, A;
Lee, SM;
(2015)
Cost-effectiveness of first-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy.
BMJ Open
, 5
(7)
, Article e006733. 10.1136/bmjopen-2014-006733.
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Kottaridis, PD;
North, J;
Tsirogianni, M;
Marden, C;
Samuel, ER;
Jide-Banwo, S;
Grace, S;
(2015)
Two-Stage Priming of Allogeneic Natural Killer Cells for the Treatment of Patients with Acute Myeloid Leukemia: A Phase I Trial.
PLoS One
, 10
(6)
, Article e0123416. 10.1371/journal.pone.0123416.
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Koumoutsea, EV;
Garbowski, M;
Porter, J;
(2015)
Synergistic intracellular iron chelation combinations: mechanisms and conditions for optimizing iron mobilization.
British Journal of Haematology
, 170
(6)
pp. 874-883.
10.1111/bjh.13512.
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Kulis, M;
Merkel, A;
Heath, S;
Queirós, AC;
Schuyler, RP;
Castellano, G;
Beekman, R;
... Martín-Subero, JI; + view all
(2015)
Whole-genome fingerprint of the DNA methylome during human B cell differentiation.
Nature Genetics
, 47
(7)
pp. 746-756.
10.1038/ng.3291.
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Lavery, DL;
Martinez, P;
Gay, LJ;
Cereser, B;
Novelli, MR;
Rodriguez-Justo, M;
Meijer, SL;
... Jansen, M; + view all
(2015)
Evolution of oesophageal adenocarcinoma from metaplastic columnar epithelium without goblet cells in Barrett's oesophagus.
Gut
, 65
(6)
pp. 907-913.
10.1136/gutjnl-2015-310748.
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Lee, AJX;
Michail, M;
Quaderi, SA;
Richardson, JA;
Aggarwal, SK;
Speechly-Dick, ME;
(2015)
Implementation of NICE Clinical Guideline 95 for assessment of stable chest pain in a rapid access chest pain clinic reduces the mean number of investigations and cost per patient.
Open Heart
, 2
(1)
, Article e000151. 10.1136/openhrt-2014-000151.
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Levine, AP;
Connor, TM;
Oygar, DD;
Neild, GH;
Segal, AW;
Maxwell, PH;
Gale, DP;
(2015)
Combinatorial Conflicting Homozygosity (CCH) analysis enables the rapid identification of shared genomic regions in the presence of multiple phenocopies.
BMC Genomics
, 16
, Article 163. 10.1186/s12864-015-1360-4.
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Levine, AP;
Duchen, MR;
de Villiers, S;
Rich, PR;
Segal, AW;
(2015)
Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity.
PLoS One
, 10
(4)
, Article e0125906. 10.1371/journal.pone.0125906.
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Löhle, M;
Hughes, D;
Milligan, A;
Richfield, L;
Reichmann, H;
Mehta, A;
Schapira, AH;
(2015)
Clinical prodromes of neurodegeneration in Anderson-Fabry disease.
Neurology
, 84
(14)
1454 - 1464.
10.1212/WNL.0000000000001450.
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Maruani, A;
Smith, ME;
Miranda, E;
Chester, KA;
Chudasama, V;
Caddick, S;
(2015)
A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy.
Nat Commun
, 6
, Article 6645. 10.1038/ncomms7645.
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Mazza, G;
Rombouts, K;
Rennie Hall, A;
Urbani, L;
Vinh Luong, T;
Al-Akkad, W;
Longato, L;
... Pinzani, M; + view all
(2015)
Decellularized human liver as a natural 3D-scaffold for liver bioengineering and transplantation.
Scientific Reports
, 5
, Article 13079. 10.1038/srep13079.
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McDonald, SAC;
Graham, TA;
Lavery, DL;
Wright, NA;
Jansen, M;
(2015)
The Barrett's Gland in Phenotype Space.
Cellular and Molecular Gastroenterology and Hepatology
, 1
(1)
pp. 41-54.
10.1016/j.jcmgh.2014.10.001.
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Morris, TJ;
Beck, S;
(2015)
Analysis pipelines and packages for Infinium HumanMethylation450 BeadChip (450k) data.
Methods
, 72
3 - 8.
10.1016/j.ymeth.2014.08.011.
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Mukherjee, S;
Hurt, CN;
Gwynne, S;
Bateman, A;
Gollins, S;
Radhakrishna, G;
Hawkins, M;
... Crosby, T; + view all
(2015)
NEOSCOPE: a randomised Phase II study of induction chemotherapy followed by either oxaliplatin/capecitabine or paclitaxel/carboplatin based chemoradiation as pre-operative regimen for resectable oesophageal adenocarcinoma.
BMC Cancer
, 15
, Article 48. 10.1186/s12885-015-1062-y.
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Mura, M;
Hopkins, TG;
Michael, T;
Abd-Latip, N;
Weir, J;
Aboagye, E;
Mauri, F;
... Blagden, SP; + view all
(2015)
LARP1 post-transcriptionally regulates mTOR and contributes to cancer progression.
Oncogene
, 34
(39)
pp. 5025-5036.
10.1038/onc.2014.428.
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Nunes, JP;
Morais, M;
Vassileva, V;
Robinson, E;
Rajkumar, VS;
Smith, ME;
Pedley, RB;
... Chudasama, V; + view all
(2015)
Functional native disulfide bridging enables delivery of a potent, stable and targeted antibody-drug conjugate (ADC).
Chemical Communications
, 51
(53)
pp. 10624-10627.
10.1039/c5cc03557k.
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Ohnmacht, SA;
Marchetti, C;
Gunaratnam, M;
Besser, RJ;
Haider, SM;
Di Vita, G;
Lowe, HL;
... Neidle, S; + view all
(2015)
A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer.
Scientific Reports
, 5
, Article 11385. 10.1038/srep11385.
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Oza, AM;
Cook, AD;
Pfisterer, J;
Embleton, A;
Ledermann, JA;
Pujade-Lauraine, E;
Kristensen, G;
... ICON7, trial investigators; + view all
(2015)
Standard chemotherapy with or without bevacizumab for women with newly diagnosed ovarian cancer (ICON7): overall survival results of a phase 3 randomised trial.
Lancet Oncology
, 16
(8)
pp. 928-936.
10.1016/S1470-2045(15)00086-8.
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Pallett, LJ;
Gill, US;
Quaglia, A;
Sinclair, LV;
Jover-Cobos, M;
Schurich, A;
Singh, KP;
... Maini, MK; + view all
(2015)
Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells.
Nature Medicine
, 21
(6)
pp. 591-600.
10.1038/nm.3856.
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Paul, DS;
Jones, A;
Sellar, RS;
Mayor, NP;
Feber, A;
Webster, AP;
Afonso, N;
... Beck, S; + view all
(2015)
A donor-specific epigenetic classifier for acute graft-versus-host disease severity in hematopoietic stem cell transplantation.
Genome Medicine
, 7
(1)
, Article 128. 10.1186/s13073-015-0246-z.
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Phillips, EH;
Westwood, JP;
Brocklebank, V;
Wong, EKS;
Tellez, JO;
Marchbank, KJ;
Mcguckin, S;
... Scully, MA; + view all
(2015)
The role of ADAMTS-13 activity and complement mutational analysis in differentiating acute thrombotic microangiopathies.
Journal of Thrombosis and Haemostasis
, 14
(1)
pp. 175-185.
10.1111/jth.13189.
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Pipinikas, C;
Dibra, H;
Karpathakis, A;
Feber, A;
Novelli, M;
Oukrif, D;
Fusai, G;
... Thirlwell, C; + view all
(2015)
Epigenetic dysregulation and poorer prognosis in DAXX-deficient pancreatic neuroendocrine tumours.
[Letter].
Endocrine-Related Cancer
, 22
(3)
L13-L18.
10.1530/ERC-15-0108.
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Rahman, S;
Housein, Z;
Dabrowska, A;
Mayán, MD;
Boobis, AR;
Hajji, N;
(2015)
E2F1-mediated FOS induction in arsenic trioxide-induced cellular transformation: effects of global H3K9 hypoacetylation and promoter-specific hyperacetylation in vitro.
Environ Health Perspect
, 123
(5)
pp. 484-492.
10.1289/ehp.1408302.
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Rajkomar, A;
Mayer, A;
Blandford, AE;
(2015)
Understanding safety-critical interactions with a home medical device through Distributed Cognition.
Journal of Biomedical Informatics
, 56
pp. 179-194.
10.1016/j.jbi.2015.06.002.
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Ramasawmy, R;
Campbell-Washburn, AE;
Wells, JA;
Johnson, SP;
Pedley, RB;
Walker-Samuel, S;
Lythgoe, MF;
(2015)
Hepatic arterial spin labelling MRI: an initial evaluation in mice.
NMR in Biomedicine
, 28
(2)
pp. 272-280.
10.1002/nbm.3251.
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Roques, M;
Wall, RJ;
Douglass, AP;
Ramaprasad, A;
Ferguson, DJ;
Kaindama, ML;
Brusini, L;
... Tewari, R; + view all
(2015)
Plasmodium P-Type Cyclin CYC3 Modulates Endomitotic Growth during Oocyst Development in Mosquitoes.
PLOS Pathogens
, 11
(11)
, Article e1005273. 10.1371/journal.ppat.1005273.
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Rudan, MV;
Barrington, C;
Henderson, S;
Ernst, C;
Odom, DT;
Tanay, A;
Hadjur, S;
(2015)
Comparative Hi-C Reveals that CTCF Underlies Evolution of Chromosomal Domain Architecture.
Cell Reports
, 10
(8)
pp. 1297-1309.
10.1016/j.celrep.2015.02.004.
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Samani, A;
Davagnanam, I;
Cockerell, OC;
Ramsay, A;
Patani, R;
Chataway, J;
(2015)
Lymphomatosis Cerebri: a treatable cause of rapidly progressive dementia.
Journal of Neurology, Neurosurgery & Psychiatry
, 86
(2)
pp. 238-240.
10.1136/jnnp-2013-307327.
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Shimizu, Y;
Taraborrelli, L;
Walczak, H;
(2015)
Linear ubiquitination in immunity.
Immunol Rev
, 266
(1)
pp. 190-207.
10.1111/imr.12309.
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Smith, AM;
Sewell, GW;
Levine, AP;
Chew, TS;
Dunne, J;
O'Shea, NR;
Smith, PJ;
... Segal, AW; + view all
(2015)
Disruption of macrophage pro-inflammatory cytokine release in Crohn's disease is associated with reduced optineurin expression in a subset of patients.
Immunology
, 144
(1)
45 - 55.
10.1111/imm.12338.
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Smith, L;
McCourt, O;
Heinrich, M;
Paton, B;
Yong, K;
Wardle, J;
Fisher, A;
(2015)
Multiple myeloma and physical activity: a scoping review.
BMJ Open
, 5
, Article e009576. 10.1136/bmjopen-2015-009576.
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Smith, NMG;
Mlcochova, P;
Watters, SA;
Aasa-Chapman, MMI;
Rabin, N;
Moore, S;
Edwards, SG;
... Gupta, RK; + view all
(2015)
Proof of principle for immune control of 1 global HIV1 reactivation in vivo.
Clinical Infectious Diseases
10.1093/cid/civ219.
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Spiro, SG;
Hackshaw, A;
(2015)
Research in progress—LungSEARCH: a randomised controlled trial of surveillance for the early detection of lung cancer in a high-risk group.
Thorax
, 71
pp. 91-93.
10.1136/thoraxjnl-2015-207433.
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Stowe, C;
Pizzey, A;
Kalber, T;
Badar, A;
Lythgoe, M;
Pule, M;
(2015)
Flow-Based Single Cell Deposition for High-Throughput Screening of Protein Libraries.
PLoS One
, 10
(11)
, Article e0140730. 10.1371/journal.pone.0140730.
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Tan, G;
Muffato, M;
Ledergerber, C;
Herrero, J;
Goldman, N;
Gil, M;
Dessimoz, C;
(2015)
Current Methods for Automated Filtering of Multiple Sequence Alignments Frequently Worsen Single-Gene Phylogenetic Inference.
Systematic Biology
, 64
(5)
pp. 778-791.
10.1093/sysbio/syv033.
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Taylor, RM;
Fern, LA;
Solanki, A;
Hooker, L;
Carluccio, A;
Pye, J;
Jeans, D;
... Whelan, JS; + view all
(2015)
Development and validation of the BRIGHTLIGHT Survey, a patient-reported experience measure for young people with cancer.
Health and Quality of Life Outcomes
, 13
, Article 107. 10.1186/s12955-015-0312-7.
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Teschendorff, AE;
Lee, SH;
Jones, A;
Fiegl, H;
Kalwa, M;
Wagner, W;
Chindera, K;
... Widschwendter, M; + view all
(2015)
HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer.
Genome Medicine
, 7
(1)
, Article 108. 10.1186/s13073-015-0233-4.
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Tinsley, S;
Meja, K;
Shepherd, C;
Khwaja, A;
(2015)
Synergistic induction of cell death in haematological malignancies by combined phosphoinositide-3-kinase and BET bromodomain inhibition.
British Journal of Haematology
, 170
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pp. 275-278.
10.1111/bjh.13283.
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Valle, JW;
Wasan, H;
Lopes, A;
Backen, AC;
Palmer, DH;
Morris, K;
Duggan, M;
... Bridgewater, JA; + view all
(2015)
Cediranib or placebo in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer (ABC-03): a randomised phase 2 trial.
Lancet Oncology
, 16
(8)
pp. 967-978.
10.1016/S1470-2045(15)00139-4.
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Vicencio, JM;
Yellon, DM;
Sivaraman, V;
Das, D;
Boi-Doku, C;
Arjun, S;
Zheng, Y;
... Davidson, SM; + view all
(2015)
Plasma exosomes protect the myocardium from ischemia-reperfusion injury.
Journal of the American College of Cardiology
, 65
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pp. 1525-1536.
10.1016/j.jacc.2015.02.026.
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Vlachogiannis, G;
Niederhuth, CE;
Tuna, S;
Stathopoulou, A;
Viiri, K;
de Rooij, DG;
Jenner, RG;
... Ooi, SK; + view all
(2015)
The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis.
Cell Rep
, 10
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pp. 944-956.
10.1016/j.celrep.2015.01.021.
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Waters, AM;
Asfahani, R;
Carroll, P;
Bicknell, L;
Lescai, F;
Bright, A;
Chanudet, E;
... Beales, PL; + view all
(2015)
The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes.
J Med Genet
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147 - 156.
10.1136/jmedgenet-2014-102691.
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Werdehausen, R;
Mittnacht, S;
McLaughlin, LA;
Minett, MS;
Armbruster, A;
Bauer, I;
Wood, JN;
... Eulenburg, V; + view all
(2015)
The lidocaine metabolite N-ethylglycine has antinociceptive effects in experimental inflammatory and neuropathic pain.
PAIN
, 156
(9)
pp. 1647-1659.
10.1097/j.pain.0000000000000206.
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Wilson, D;
Charidimou, A;
Shakeshaft, C;
Ambler, G;
White, M;
Cohen, H;
Yousry, T;
... Werring, DJ; + view all
(2015)
Volume and functional outcome of intracerebral hemorrhage according to oral anticoagulant type.
Neurology
, 86
(4)
pp. 360-366.
10.1212/WNL.0000000000002310.
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Yang, JHM;
Cutler, AJ;
Ferreira, RC;
Reading, JL;
Cooper, NJ;
Wallace, C;
Clarke, P;
... Tree, TIM; + view all
(2015)
Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes.
Diabetes
, 64
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pp. 3891-3902.
10.2337/db15-0516.
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Zelenay, S;
van der Veen, AG;
Boettcher, JP;
Snelgrove, KJ;
Rogers, N;
Acton, SE;
Chakravarty, P;
... Reis e Sousa, C; + view all
(2015)
Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity.
Cell
, 162
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pp. 1257-1270.
10.1016/j.cell.2015.08.015.
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Conference item
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Embleton, AC;
Clark, E;
Townsend, S;
Farrelly, L;
Jones, C;
Kaplan, R;
(2015)
Impact of retrospective data verification on the results of the academic-led ICON6 trial.
Presented at: 3rd International Clinical Trials Methodology Conference, Glasgow, UK.
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Thesis
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Alnabhan, RM;
(2015)
Study of the Activation of Peripheral Blood and Cord Blood Natural Killer Cells.
Doctoral thesis , UCL (University College London).
|
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Alvarez González, C;
(2015)
Human umbilical cord stem cells for regenerative neurology: generation of neural-derived progenitors.
Doctoral thesis , UCL (University College London).
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Bagnobianchi, A;
(2015)
The Molecular Mechanism of Action of Bendamustine.
Doctoral thesis , UCL (University College London).
|
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Bain, OW;
(2015)
In vitro enhancement of retention and vascular support capacity of bone marrow derived stem cells for cardiac repair.
Doctoral thesis , UCL (University College London).
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Dewhurst, SM;
(2015)
Whole genome doubling propagates chromosomal instability and accelerates cancer genome evolution.
Doctoral thesis , UCL (University College London).
|
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Gains, JE;
(2015)
Improving the outcomes for high-risk neuroblastoma through the optimisation of radiotherapeutic techniques.
Doctoral thesis , UCL (University College London).
|
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Goldstein, RM;
(2015)
Development of the G3 Designed ankyrin repeat protein (DARPin) for HER2 imaging.
Doctoral thesis , UCL (University College London).
|
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Griffin, JE;
(2015)
Generation of Mycophenolate Mofetil Resistant Lymphocytes for Adoptive Immunotherapy.
Doctoral thesis , UCL (University College London).
|
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Grimshaw, BD;
(2015)
Developing a universal T cell for use in adoptive immunotherapy.
Doctoral thesis , UCL (University College London).
|
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|
Jamal-Hanjani, M;
(2015)
The role of intratumour heterogeneity and chromosomal instability in cancer.
Doctoral thesis , UCL (University College London).
|
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Jayakody Arachchillage, DR;
(2015)
Interactions between antiphospholipid antibodies, oral anticoagulants and haemostasis activation in thrombotic antiphospholipid syndrome.
Doctoral thesis , UCL (University College London).
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Jenkinson, S;
(2015)
Investigation of genetic alterations in paediatric patients with T-cell lymphoblastic leukaemia.
Doctoral thesis , UCL (University College London).
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Karpathakis, A;
(2015)
Molecular profiling of gastrointestinal neuroendocrine tumours.
Doctoral thesis , UCL (University College London).
|
|
Levine, AP;
(2015)
The genetics of inflammatory bowel disease in extended multiplex Ashkenazi Jewish kindreds.
Doctoral thesis , UCL (University College London).
|
|
Loddo, M;
(2015)
Dysregulation of the cell cycle in breast cancer.
Doctoral thesis , UCL (University College London).
|
|
McGranahan, NL;
(2015)
Mechanisms of cancer evolution and drivers of tumour heterogeneity.
Doctoral thesis , UCL (University College London).
|
|
Papastavrou, YR;
(2015)
Use of Multicomponent Non-Rigid Registration to Improve Alignment of Serial Oncological PET/CT Studies.
Doctoral thesis , UCL (University College London).
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Percy, LA;
(2015)
Exploring mechanisms of drug resistance in multiple myeloma: the roles of the progenitor compartment, APRIL and Notch signalling.
Doctoral thesis , UCL (University College London).
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Philip, BM;
(2015)
RQR8: A universal safety switch for cellular therapies.
Doctoral thesis , UCL (University College London).
|
|
Sanber, KSR;
(2015)
Production of self-inactivating lentiviral vectors by constitutive packaging cell lines for gene therapy clinical applications.
Doctoral thesis , UCL (University College London).
|
|
Shemais, TAH;
(2015)
The epigenetic differences between neurofibromas and malignant peripheral nerve sheath tumours.
Doctoral thesis , UCL (University College London.
|
|
Stewart, SK;
(2015)
DNA hydroxymethylation and methylation dynamics during neural differentiation.
Doctoral thesis , UCL (University College London).
|
|
Underwood, MI;
(2015)
The relationship between ADAMTS13 genotype and phenotype in congenital thrombotic thrombocytopenic purpura and characterisation of ADAMTS13 mutants.
Doctoral thesis , UCL (University College London).
|
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|
Westwood, J-P;
(2015)
The Role of Complement Anaphylatoxins in Systemic Disease.
Doctoral thesis , UCL (University College London).
|
|
Zareian, Nahid;
(2015)
Dissecting the role of cooperating genetic lesions in acute leukaemia.
Doctoral thesis (Ph.D), UCL (University College London).
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