Browse by UCL people
Group by: Type | Date
Number of items: 66.
Article
Andrews, WD;
Davidson, K;
Tamamaki, N;
Ruhrberg, C;
Parnavelas, JG;
(2016)
Altered proliferative ability of neuronal progenitors in PlexinA1 mutant mice.
Journal of Comparative Neurology
, 524
(3)
pp. 518-534.
10.1002/cne.23806.
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Barber, M;
Andrews, WD;
Memi, F;
Gardner, P;
Ciantar, D;
Tata, M;
Ruhrberg, C;
(2018)
Vascular-derived Vegfa promotes cortical interneuron migration and proximity to the vasculature in the developing forebrain.
Cerebral Cortex
, 28
(7)
pp. 2577-2593.
10.1093/cercor/bhy082.
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Barnes, Josephine L;
Yoshida, Masahiro;
He, Peng;
Worlock, Kaylee B;
Lindeboom, Rik GH;
Suo, Chenqu;
Pett, J Patrick;
... Nikolić, Marko Z; + view all
(2023)
Early human lung immune cell development and its role in epithelial cell fate.
Science Immunology
, 8
(90)
, Article eadf9988. 10.1126/sciimmunol.adf9988.
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Brash, James T;
Diez-Pinel, Guillermo;
Colletto, Chiara;
Castellan, Raphael FP;
Fantin, Alessandro;
Ruhrberg, Christiana;
(2024)
The BulkECexplorer compiles endothelial bulk transcriptomes to predict functional versus leaky transcription.
Nature Cardiovascular Research
10.1038/s44161-024-00436-w.
(In press).
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Brash, James T;
Ruhrberg, Christiana;
Fantin, Alessandro;
(2022)
Evaluating VEGF-Induced Vascular Leakage Using the Miles Assay.
Methods in Molecular Biology
, 2475
pp. 289-295.
10.1007/978-1-0716-2217-9_21.
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Brash, JT;
Bolton, RL;
Rashbrook, VS;
Denti, L;
Kubota, Y;
Ruhrberg, C;
(2020)
Tamoxifen-Activated Cre Impairs Retinal Angiogenesis Independently of Gene Deletion.
Circulation Research
, 127
(6)
pp. 849-850.
10.1161/CIRCRESAHA.120.317025.
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Brash, JT;
Denti, L;
Ruhrberg, C;
Bucher, F;
(2019)
VEGF188 promotes corneal reinnervation after injury.
JCI Insight
, 4
(21)
, Article e130979. 10.1172/jci.insight.130979.
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Brash, JT;
Ruhrberg, C;
Fantin, A;
(2018)
Evaluating Vascular Hyperpermeability-inducing Agents in the Skin with the Miles Assay.
Journal of Visualized Experiments
(136)
, Article e57524. 10.3791/57524.
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Canu, G;
Ruhrberg, C;
(2021)
First blood: the endothelial origins of hematopoietic progenitors.
Angiogenesis
10.1007/s10456-021-09783-9.
(In press).
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Castellan, RF;
Vitiello, M;
Vidmar, M;
Johnstone, S;
Iacobazzi, D;
Mellis, D;
Cathcart, B;
... Meloni, M; + view all
(2020)
Mir-96 and miR-183 differentially regulate neonatal and adult post-infarct neovascularisation.
JCI Insight
10.1172/jci.insight.134888.
(In press).
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Cattin, AL;
Burden, JJ;
Van Emmenis, L;
Mackenzie, FE;
Hoving, JJ;
Garcia Calavia, N;
Guo, Y;
... Lloyd, AC; + view all
(2015)
Macrophage-Induced Blood Vessels Guide Schwann Cell-Mediated Regeneration of Peripheral Nerves.
Cell
, 162
(5)
pp. 1127-1139.
10.1016/j.cell.2015.07.021.
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Ceccacci, Elena;
Villa, Emanuela;
Santoro, Fabio;
Minucci, Saverio;
Ruhrberg, Christiana;
Fantin, Alessandro;
(2023)
A Refined Single Cell Landscape of Haematopoiesis in the Mouse Foetal Liver.
Journal of Developmental Biology
, 11
(2)
, Article 15. 10.3390/jdb11020015.
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Charoy, C;
Dinvaut, S;
Chaix, Y;
Morlé, L;
Sanyas, I;
Bozon, M;
Kindbeiter, K;
... Castellani, V; + view all
(2017)
Genetic specification of left-right asymmetry in the diaphragm muscles and their motor innervation.
eLife
, 6
, Article e18481. 10.7554/eLife.18481.
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D'Amico, Gabriela;
Ruhrberg, Christiana;
(2022)
The Embryonic Mouse Hindbrain Model to Study Sprouting Angiogenesis In Vivo.
Methods in Molecular Biology
, 2441
pp. 3-18.
10.1007/978-1-0716-2059-5_1.
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Diez-Pinel, Guillermo;
Muratore, Alessandro;
Ruhrberg, Christiana;
Canu, Giovanni;
(2026)
Discovery of New Markers for Haemogenic Endothelium and Haematopoietic Progenitors in the Mouse Yolk Sac.
Journal of Developmental Biology
, 14
(1)
, Article 4. 10.3390/jdb14010004.
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Erickson, Alek G;
Motta, Alessia;
Kastriti, Maria Eleni;
Edwards, Steven;
Coulpier, Fanny;
Théoulle, Emy;
Murtazina, Aliia;
... Adameyko, Igor; + view all
(2024)
Motor innervation directs the correct development of the mouse sympathetic nervous system.
Nature Communications
, 15
, Article 7065. 10.1038/s41467-024-51290-0.
(In press).
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Erskine, L;
Francois, U;
Denti, L;
Joyce, A;
Tillo, M;
Bruce, F;
Vargesson, N;
(2017)
VEGF-A and neuropilin 1 (NRP1) shape axon projections in the developing CNS via dual roles in neurons and blood vessels.
Development
, 144
(13)
pp. 2504-2516.
10.1242/dev.151621.
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Fantin, A;
Tacconi, C;
Villa, E;
Ceccacci, E;
Denti, L;
Ruhrberg, C;
(2021)
KIT Is Required for Fetal Liver Hematopoiesis.
Frontiers in Cell and Developmental Biology
, 9
, Article 648630. 10.3389/fcell.2021.648630.
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Fantin, Alessandro;
Ruhrberg, Christiana;
(2022)
The Embryonic Mouse Hindbrain and Postnatal Retina as In Vivo Models to Study Angiogenesis.
Methods in Molecular Biology
, 2475
pp. 275-287.
10.1007/978-1-0716-2217-9_20.
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Fantin, A;
Herzog, B;
Mahmoud, M;
Yamaji, M;
Plein, A;
Denti, L;
Ruhrberg, C;
(2014)
Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis.
Development
, 141
pp. 556-562.
10.1242/dev.103028.
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Fantin, A;
Lampropoulou, A;
Gestri, G;
Raimondi, C;
Senatore, V;
Zachary, I;
Ruhrberg, C;
(2015)
NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells.
Cell Reports
, 13
(9)
pp. 1577-1590.
10.1016/j.celrep.2015.11.049.
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Fantin, A;
Lampropoulou, A;
Gestri, G;
Raimondi, C;
Senatore, V;
Zachary, I;
Ruhrberg, C;
(2015)
NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells.
Cell Reports
, 11
(10)
pp. 1577-1590.
10.1016/j.celrep.2015.05.018.
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Fantin, A;
Lampropoulou, A;
Senatore, V;
Brash, JT;
Prahst, C;
Lange, CA;
Liyanage, SE;
... Ruhrberg, C; + view all
(2017)
VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation.
Journal of Experimental Medicine
, 214
(4)
pp. 1049-1064.
10.1084/jem.20160311.
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Gerhardt, H;
Golding, M;
Fruttiger, M;
Ruhrberg, C;
Lundkvist, A;
Abramsson, A;
Jeltsch, M;
... Betsholtz, C; + view all
(2003)
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia.
J CELL BIOL
, 161
(6)
1163 - 1177.
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Hasan, Sana S;
John, David;
Rudnicki, Martina;
AlZaim, Ibrahim;
Eberhard, Daniel;
Moll, Iris;
Taylor, Jacqueline;
... Fischer, Andreas; + view all
(2025)
Obesity drives depot-specific vascular remodeling in male white adipose tissue.
Nature Communications
, 16
(1)
, Article 5392. 10.1038/s41467-025-60910-2.
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Howard, S;
Oleari, R;
Poliandri, A;
Chantzara, V;
Fantin, A;
Ruiz-Babot, G;
Metherell, L;
... Dunkel, L; + view all
(2018)
HS6ST1 insufficiency causes self-limited delayed puberty in contrast with other GnRH deficiency genes.
Journal of Clinical Endocrinology and Metabolism
, 103
(9)
pp. 3420-3429.
10.1210/jc.2018-00646.
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Ioannou, Elena;
Ruhrberg, Christiana;
(2022)
Whole-Mount Immunofluorescence Protocol for 3D Imaging, Reconstruction, and Quantification of Fourth Pharyngeal Arch Artery Formation.
Methods in Molecular Biology
, 2441
pp. 41-62.
10.1007/978-1-0716-2059-5_4.
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Jafree, DJ;
Long, DA;
Scambler, PJ;
Ruhrberg, C;
(2021)
Mechanisms and cell lineages in lymphatic vascular development.
Angiogenesis
10.1007/s10456-021-09784-8.
(In press).
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Jafree, DJ;
Moulding, D;
Kolatsi-Joannou, M;
Perretta Tejedor, N;
Price, KL;
Milmoe, NJ;
Walsh, CL;
... Long, DA; + view all
(2020)
Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease.
eLife
, 8
, Article e48183. 10.7554/eLife.48183.
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Lanahan, A;
Zhang, X;
Fantin, A;
Zhuang, Z;
Rivera-Molina, F;
Speichinger, K;
Prahst, C;
... Simons, M; + view all
(2013)
The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis.
Dev Cell
, 25
(2)
156 - 168.
10.1016/j.devcel.2013.03.019.
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Le, Viet-Hang;
Orniacki, Clarisse;
Murcia-Belmonte, Verónica;
Denti, Laura;
Schütz, Dagmar;
Stumm, Ralf;
Ruhrberg, Christiana;
(2024)
CXCL12 promotes the crossing of retinal ganglion cell axons at the optic chiasm.
Development
, 151
(2)
, Article dev202446. 10.1242/dev.202446.
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Liyanage, SE;
Fantin, A;
Villacampa, P;
Lange, CA;
Denti, L;
Cristante, E;
Smith, AJ;
... Ruhrberg, C; + view all
(2016)
Myeloid-Derived Vascular Endothelial Growth Factor and Hypoxia-Inducible Factor Are Dispensable for Ocular Neovascularization-Brief Report.
Arteriosclerosis, Thrombosis, and Vascular Biology
, 36
(1)
pp. 19-24.
10.1161/ATVBAHA.115.306681.
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Lumb, R;
Tata, M;
Xu, X;
Joyce, A;
Marchant, C;
Harvey, N;
Ruhrberg, C;
(2018)
Neuropilins guide preganglionic sympathetic axons and chromaffin cell precursors to establish the adrenal medulla.
Development
10.1242/dev.162552.
(In press).
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Marie Delalande, J;
Natarajan, D;
Vernay, B;
Finlay, M;
Ruhrberg, C;
Thapar, N;
Burns, AJ;
(2014)
Vascularisation is not necessary for gut colonisation by enteric neural crest cells.
Dev Biol
, 385
(2)
pp. 220-229.
10.1016/j.ydbio.2013.11.007.
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Oleari, R;
Caramello, A;
Campinoti, S;
Lettieri, A;
Ioannou, E;
Paganoni, A;
Fantin, A;
... Ruhrberg, C; + view all
(2019)
Plxna1 and Plxna3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons.
Development
, 146
, Article dev176461. 10.1242/dev.176461.
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Plein, A;
Fantin, A;
Denti, L;
Pollard, JW;
Ruhrberg, C;
(2018)
Erythro-myeloid progenitors contribute endothelial cells to blood vessels.
Nature
, 562
pp. 223-228.
10.1038/s41586-018-0552-x.
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Plein, A;
Fantin, A;
Ruhrberg, C;
(2014)
Neuropilin regulation of angiogenesis, arteriogenesis and vascular permeability.
Microcirculation
, 21
(4)
pp. 315-323.
10.1111/micc.12124.
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Raimondi, C;
Brash, JT;
Fantin, A;
Ruhrberg, C;
(2016)
NRP1 function and targeting in neurovascular development and eye disease.
Progress in Retinal and Eye Research
, 52
pp. 64-83.
10.1016/j.preteyeres.2016.02.003.
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Raimondi, C;
Fantin, A;
Lampropoulou, A;
Denti, L;
Chikh, A;
Ruhrberg, C;
(2014)
Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells.
The Journal of Experimental Medicine
, 211
(6)
pp. 1167-1183.
10.1084/jem.20132330.
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Rashbrook, Victoria S;
Brash, James T;
Ruhrberg, Christiana;
(2022)
Cre toxicity in mouse models of cardiovascular physiology and disease.
Nature Cardiovascular Research
, 1
pp. 806-816.
10.1038/s44161-022-00125-6.
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Rashbrook, Victoria S;
Denti, Laura;
Ruhrberg, Christiana;
(2023)
Tamoxifen exacerbates morbidity and mortality in male mice receiving medetomidine anaesthesia.
Animal Welfare
, 32
, Article e78. 10.1017/awf.2023.98.
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Roth, L;
Prahst, C;
Ruckdeschel, T;
Savant, S;
Westrom, S;
Fantin, A;
Riedel, M;
... Augustin, HG; + view all
(2016)
Neuropilin-1 mediates vascular permeability independently of vascular endothelial growth factor receptor-2 activation.
Science Signaling
, 9
(425)
, Article ra42. 10.1126/scisignal.aad3812.
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Ruhrberg, Christiana;
Brash, James T;
Diez-Pinel, Guillermo;
Rinaldi, Luca;
Castellan, Raphael FP;
Fantin, Alessandro;
(2025)
Endothelial transcriptomic, epigenomic and proteomic data challenge the proposed role for TSAd in vascular permeability.
Angiogenesis
, 28
(2)
, Article 21. 10.1007/s10456-025-09971-x.
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Ruhrberg, C;
(2001)
Endogenous inhibitors of angiogenesis.
J CELL SCI
, 114
(18)
3215 - 3216.
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Ruhrberg, C;
Hajibagheri, MAN;
Parry, DAD;
Watt, FM;
(1997)
Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin.
J CELL BIOL
, 139
(7)
1835 - 1849.
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Ruhrberg, C;
Hajibagheri, MAN;
Simon, M;
Dooley, TP;
Watt, FM;
(1996)
Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin.
J CELL BIOL
, 134
(3)
715 - 729.
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Schwarz, Q;
Maden, CH;
Davidson, K;
Ruhrberg, C;
(2009)
Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root ganglia.
DEVELOPMENT
, 136
(11)
1785 - 1789.
10.1242/dev.034322.
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Schwarz, Q;
Maden, CH;
Vieira, JM;
Ruhrberg, C;
(2009)
Neuropilin 1 signaling guides neural crest cells to coordinate pathway choice with cell specification.
P NATL ACAD SCI USA
, 106
(15)
6164 - 6169.
10.1073/pnas.0811521106.
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Schwarz, Q;
Vieira, JM;
Howard, B;
Eickholt, BJ;
Ruhrberg, C;
(2008)
Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells.
DEVELOPMENT
, 135
(9)
1605 - 1613.
10.1242/dev.015412.
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Shibata-Germanos, S;
Goodman, JR;
Grieg, A;
Trivedi, CA;
Benson, BC;
Foti, SC;
Faro, A;
... Rihel, J; + view all
(2019)
Structural and functional conservation of non-lumenized lymphatic endothelial cells in the mammalian leptomeninges.
Acta Neuropathologica
10.1007/s00401-019-02091-z.
(In press).
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Tacconi, Carlotta;
Plein, Alice;
Colletto, Chiara;
Villa, Emanuela;
Denti, Laura;
Barone, Cristiana;
Javanmardi, Yousef;
... Ruhrberg, Christiana; + view all
(2022)
KIT is dispensable for physiological organ vascularisation in the embryo.
Angiogenesis
10.1007/s10456-022-09837-6.
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Takaoka, Minoru;
Zhao, Xiaohui;
Lim, Hwee Ying;
Magnussen, Costan G;
Ang, Owen;
Suffee, Nadine;
Schrank, Patricia R;
... Mallat, Ziad; + view all
(2024)
Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis.
Nature
, 634
pp. 457-465.
10.1038/s41586-024-07993-x.
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Tata, M;
Ruhrberg, C;
(2018)
Cross-talk between blood vessels and neural progenitors in the developing brain.
Neuronal Signaling
, 2
(1)
, Article NS20170139. 10.1042/NS20170139.
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Tata, M;
Ruhrberg, C;
(2018)
The Mouse Hindbrain As a Model for Studying Embryonic Neurogenesis.
Journal of Visualized Experiments
(131)
, Article e56793. 10.3791/56793.
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Tata, M;
Ruhrberg, C;
Fantin, A;
(2015)
Vascularisation of the central nervous system.
Mechanisms of Development
, 138
(1)
pp. 26-36.
10.1016/j.mod.2015.07.001.
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Tata, M;
Wall, I;
Joyce, A;
Vieira, JM;
Kessaris, N;
Ruhrberg, C;
(2016)
Regulation of embryonic neurogenesis by germinal zone vasculature.
Proceedings of the National Academy of Sciences of the United States of America
, 113
(47)
pp. 13414-13419.
10.1073/pnas.1613113113.
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Tillo, M;
Charoy, C;
Schwarz, Q;
Maden, CH;
Davidson, K;
Fantin, A;
Ruhrberg, C;
(2016)
2- and 6-O-sulfated proteoglycans have distinct and complementary roles in cranial axon guidance and motor neuron migration.
Development
, 143
(11)
pp. 1907-1913.
10.1242/dev.126854.
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Tillo, M;
Erskine, L;
Cariboni, A;
Fantin, A;
Joyce, A;
Denti, L;
Ruhrberg, C;
(2015)
VEGF189 binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the developing brain.
Development
, 142
(2)
314 - 319.
10.1242/dev.115998.
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Tillo, M;
Ruhrberg, C;
Mackenzie, F;
(2012)
Emerging roles for semaphorins and VEGFs in synaptogenesis and synaptic plasticity.
Cell Adhesion & Migration
, 6
(6)
541 - 546.
10.4161/cam.22408.
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Tillo, M;
Schwarz, Q;
Ruhrberg, C;
(2014)
Mouse hindbrain ex vivo culture to study facial branchiomotor neuron migration.
Journal of Visualized Experiments
, 85
, Article e51397. 10.3791/51397.
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Vieira, JR;
Shah, B;
Dupraz, S;
Paredes, I;
Himmels, P;
Schermann, G;
Adler, H;
... Ruiz de Almodóvar, C; + view all
(2022)
Endothelial PlexinD1 signaling instructs spinal cord vascularization and motor neuron development.
Neuron
, 110
(24)
4074-4089.e6.
10.1016/j.neuron.2022.12.005.
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Whisler, Jordan;
Shahreza, Somayeh;
Schlegelmilch, Karin;
Ege, Nil;
Javanmardi, Yousef;
Malandrino, Andrea;
Agrawal, Ayushi;
... Moeendarbary, Emad; + view all
(2023)
Emergent mechanical control of vascular morphogenesis.
Science Advances
, 9
(32)
, Article eadg9781. 10.1126/sciadv.adg9781.
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Book chapter
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Tata, M;
Tillo, M;
Ruhrberg, C;
(2015)
Neuropilins in Development and Disease of the Nervous System.
In: Pruszak, J, (ed.)
Neural Surface Antigens: From Basic Biology Towards Biomedical Applications.
(pp. 65-75).
Elsevier: London, UK.
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Thesis
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Navarro-Aragall, Ariadna Gador;
(2019)
Mechanisms in murine cardiovascular development.
Doctoral thesis (Ph.D), UCL (University College London).
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Tata, MAJ;
(2016)
Vascular regulation of embryonic neurogenesis.
Doctoral thesis , UCL (University College London).
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Tillo, M;
(2015)
Defining novel molecular mechanisms in hindbrain development.
Doctoral thesis , (UCL) University College London.
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