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Number of items: 150.

2024

Breeze, Charles E; Haugen, Eric; Gutierrez-Arcelus, María; Yao, Xiaozheng; Teschendorff, Andrew; Beck, Stephan; Dunham, Ian; ... Berndt, Sonja I; + view all Breeze, Charles E; Haugen, Eric; Gutierrez-Arcelus, María; Yao, Xiaozheng; Teschendorff, Andrew; Beck, Stephan; Dunham, Ian; Stamatoyannopoulos, John; Franceschini, Nora; Machiela, Mitchell J; Berndt, Sonja I; - view fewer (2024) FORGEdb: a tool for identifying candidate functional variants and uncovering target genes and mechanisms for complex diseases. Genome Biology , 25 (1) , Article 3. 10.1186/s13059-023-03126-1.

Smeeth, Demelza; Ecker, Simone; Chervova, Olga; McEwen, Fiona; Karam, Elie; Beck, Stephan; Pluess, Michael; (2024) War Exposure and DNA Methylation in Syrian Refugee Children and Adolescents. JAMA Psychiatry 10.1001/jamapsychiatry.2024.3714. (In press).

2023

Chen, Kezhong; Kang, Guannan; Zhang, Zhihong; Lizaso, Analyn; Beck, Stephan; Lyskjær, Iben; Chervova, Olga; ... Wang, Jun; + view all Chen, Kezhong; Kang, Guannan; Zhang, Zhihong; Lizaso, Analyn; Beck, Stephan; Lyskjær, Iben; Chervova, Olga; Li, Bingsi; Shen, Haifeng; Wang, Chenyang; Li, Bing; Zhao, Heng; Li, Xi; Yang, Fan; Kanu, Nnennaya; Wang, Jun; - view fewer (2023) Individualized dynamic methylation-based analysis of cell-free DNA in postoperative monitoring of lung cancer. BMC Medicine , 21 , Article 255. 10.1186/s12916-023-02954-z.

Chen, Kezhong; Yang, Fan; Shen, Haifeng; Wang, Chenyang; Li, Xi; Chervova, Olga; Wu, Shuailai; ... Wang, Jun; + view all Chen, Kezhong; Yang, Fan; Shen, Haifeng; Wang, Chenyang; Li, Xi; Chervova, Olga; Wu, Shuailai; Qiu, Fujun; Peng, Di; Zhu, Xin; Chuai, Shannon; Beck, Stephan; Kanu, Nnennaya; Carbone, David; Zhang, Zhihong; Wang, Jun; - view fewer (2023) Individualized tumor-informed circulating tumor DNA analysis for postoperative monitoring of non-small cell lung cancer. Cancer Cell , 41 (10) 1749-1762.e6. 10.1016/j.ccell.2023.08.010.

Haefliger, Simon; Chervova, Olga; Davies, Christopher; Nottley, Steven; Hargreaves, Steven; Sumathi, Vaiyapuri P; Amary, Fernanda; ... Lyskjaer, Iben; + view all Haefliger, Simon; Chervova, Olga; Davies, Christopher; Nottley, Steven; Hargreaves, Steven; Sumathi, Vaiyapuri P; Amary, Fernanda; Tirabosco, Roberto; Pillay, Nischalan; Beck, Stephan; Flanagan, Adrienne M; Lyskjaer, Iben; - view fewer (2023) Subclassification of epithelioid sarcoma with potential therapeutic impact. The Journal of Pathology 10.1002/path.6135. (In press).

Lazebnik, Teddy; Beck, Stephan; Shami, Labib; (2023) Academic co-authorship is a risky game. Scientometrics , 128 , Article 12. 10.1007/s11192-023-04843-x.

Owen, Nicholas; Toms, Maria; Tian, Yuan; Toualbi, Lyes; Richardson, Rose; Young, Rodrigo; Tracey-White, Dhani; ... Moosajee, Mariya; + view all Owen, Nicholas; Toms, Maria; Tian, Yuan; Toualbi, Lyes; Richardson, Rose; Young, Rodrigo; Tracey-White, Dhani; Dhami, Pawan; Beck, Stephan; Moosajee, Mariya; - view fewer (2023) Loss of the crumbs cell polarity complex disrupts epigenetic transcriptional control and cell cycle progression in the developing retina. The Journal of Pathology , 259 pp. 441-454. 10.1002/path.6056.

Veturi, Yoga Advaith; Woof, William; Lazebnik, Teddy; Moghul, Ismail; Woodward-Court, Peter; Wagner, Siegfried K; Cabral de Guimarães, Thales Antonio; ... Pontikos, Nikolas; + view all Veturi, Yoga Advaith; Woof, William; Lazebnik, Teddy; Moghul, Ismail; Woodward-Court, Peter; Wagner, Siegfried K; Cabral de Guimarães, Thales Antonio; Daich Varela, Malena; Liefers, Bart; Patel, Praveen J; Beck, Stephan; Webster, Andrew R; Mahroo, Omar; Keane, Pearse A; Michaelides, Michel; Balaskas, Konstantinos; Pontikos, Nikolas; - view fewer (2023) SynthEye: Investigating the Impact of Synthetic Data on Artificial Intelligence-assisted Gene Diagnosis of Inherited Retinal Disease. Ophthalmology Science , 3 (2) , Article 100258. 10.1016/j.xops.2022.100258.

Widayati, Tyas Arum; Schneider, Jadesada; Panteleeva, Kseniia; Chernysheva, Elizabeth; Hrbkova, Natalie; Beck, Stephan; Voloshin, Vitaly; Widayati, Tyas Arum; Schneider, Jadesada; Panteleeva, Kseniia; Chernysheva, Elizabeth; Hrbkova, Natalie; Beck, Stephan; Voloshin, Vitaly; Chervova, Olga; - view fewer (2023) Open access-enabled evaluation of epigenetic age acceleration in colorectal cancer and development of a classifier with diagnostic potential. Frontiers in Genetics , 14 , Article 1258648. 10.3389/fgene.2023.1258648.

2022

Breeze, CE; Beck, S; Berndt, SI; Franceschini, N; (2022) The missing diversity in human epigenomic studies. Nature Genetics , 54 pp. 737-739. 10.1038/s41588-022-01081-4.

Breeze, CE; Haugen, E; Reynolds, A; Teschendorff, A; van Dongen, J; Lan, Q; Rothman, N; ... Berndt, SI; + view all Breeze, CE; Haugen, E; Reynolds, A; Teschendorff, A; van Dongen, J; Lan, Q; Rothman, N; Bourque, G; Dunham, I; Beck, S; Stamatoyannopoulos, J; Franceschini, N; Berndt, SI; - view fewer (2022) Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations. Genome Biololgy , 23 (1) , Article 13. 10.1186/s13059-021-02560-3.

Breeze, Charles E; Wong, Jason YY; Beck, Stephan; Berndt, Sonja I; Franceschini, Nora; (2022) Diversity in EWAS: current state, challenges, and solutions. Genome Medicine , 14 , Article 71. 10.1186/s13073-022-01065-3.

Chervova, Olga; Chernysheva, Elizabeth; Panteleeva, Kseniia; Widayati, Tyas Arum; Hrbkova, Natalie; Schneider, Jadesada; Maximov, Vladimir; ... Beck, Stephan; + view all Chervova, Olga; Chernysheva, Elizabeth; Panteleeva, Kseniia; Widayati, Tyas Arum; Hrbkova, Natalie; Schneider, Jadesada; Maximov, Vladimir; Ryabikov, Andrew; Tillmann, Taavi; Pikhart, Hynek; Bobak, Martin; Voloshin, Vitaly; Malyutina, Sofia; Beck, Stephan; - view fewer (2022) Evaluation of Epigenetic Age Acceleration Scores and Their Associations with CVD-Related Phenotypes in a Population Cohort. Biology , 12 (1) , Article 68. 10.3390/biology12010068.

Dupras, Charles; Knoppers, Terese; Palmour, Nicole; Beauchamp, Elisabeth; Liosi, Stamatina; Siebert, Reiner; Berner, Alison May; ... Joly, Yann; + view all Dupras, Charles; Knoppers, Terese; Palmour, Nicole; Beauchamp, Elisabeth; Liosi, Stamatina; Siebert, Reiner; Berner, Alison May; Beck, Stephan; Charest, Ian; Joly, Yann; - view fewer (2022) Researcher perspectives on ethics considerations in epigenetics: an international survey. Clinical Epigenetics , 14 (1) , Article 110. 10.1186/s13148-022-01322-7.

Huerne, Katherine; Palmour, Nicole; Wu, Angela Ruohao; Beck, Stephan; Berner, Alison; Siebert, Reiner; Joly, Yann; (2022) Auditing the Editor: A Review of Key Translational Issues in Epigenetic Editing. The CRISPR Journal 10.1089/crispr.2021.0094.

Lyskjær, Iben; Kara, Neesha; De Noon, Solange; Davies, Christopher; Rocha, Ana Maia; Strobl, Anna-Christina; Usher, Inga; ... Flanagan, Adrienne M; + view all Lyskjær, Iben; Kara, Neesha; De Noon, Solange; Davies, Christopher; Rocha, Ana Maia; Strobl, Anna-Christina; Usher, Inga; Gerrand, Craig; Strauss, Sandra J; Schrimpf, Daniel; von Deimling, Andreas; Beck, Stephan; Flanagan, Adrienne M; - view fewer (2022) Osteosarcoma: Novel prognostic biomarkers using circulating and cell-free tumour DNA. European Journal of Cancer , 168 pp. 1-11. 10.1016/j.ejca.2022.03.002.

Tanić, Miljana; Moghul, Ismail; Rodney, Simon; Dhami, Pawan; Vaikkinen, Heli; Ambrose, John; Barrett, James; ... Beck, Stephan; + view all Tanić, Miljana; Moghul, Ismail; Rodney, Simon; Dhami, Pawan; Vaikkinen, Heli; Ambrose, John; Barrett, James; Feber, Andrew; Beck, Stephan; - view fewer (2022) Comparison and imputation-aided integration of five commercial platforms for targeted DNA methylome analysis. Nature Biotechnology , 40 pp. 1478-1487. 10.1038/s41587-022-01336-9.

Zhu, Tianyu; Liu, Jacklyn; Beck, Stephan; Pan, Sun; Capper, David; Lechner, Matt; Thirlwell, Chrissie; ... Teschendorff, Andrew E; + view all Zhu, Tianyu; Liu, Jacklyn; Beck, Stephan; Pan, Sun; Capper, David; Lechner, Matt; Thirlwell, Chrissie; Breeze, Charles E; Teschendorff, Andrew E; - view fewer (2022) A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution. Nature Methods , 19 pp. 296-306. 10.1038/s41592-022-01412-7.

2021

Bentham, R; Litchfield, K; Watkins, TBK; Lim, EL; Rosenthal, R; Martinez-Ruiz, C; Hiley, CT; ... McGranahan, N; + view all Bentham, R; Litchfield, K; Watkins, TBK; Lim, EL; Rosenthal, R; Martinez-Ruiz, C; Hiley, CT; Al Bakir, M; Salgado, R; Moore, DA; Jamal-Hanjani, M; Swanton, C; McGranahan, N; - view fewer (2021) Using DNA sequencing data to quantify T cell fraction and therapy response. Nature , 597 pp. 555-560. 10.1038/s41586-021-03894-5.

Breeze, CE; Batorsky, A; Lee, MK; Szeto, MD; Xu, X; McCartney, DL; Jiang, R; ... Franceschini, N; + view all Breeze, CE; Batorsky, A; Lee, MK; Szeto, MD; Xu, X; McCartney, DL; Jiang, R; Patki, A; Kramer, HJ; Eales, JM; Raffield, L; Lange, L; Lange, E; Durda, P; Liu, Y; Tracy, RP; Van Den Berg, D; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TO; Evans, KL; Kraus, WE; Shah, S; Tiwari, HK; Hou, L; Whitsel, EA; Jiang, X; Charchar, FJ; Baccarelli, AA; Rich, SS; Morris, AP; Irvin, MR; Arnett, DK; Hauser, ER; Rotter, JI; Correa, A; Hayward, C; Horvath, S; Marioni, RE; Tomaszewski, M; Beck, S; Berndt, SI; London, SJ; Mychaleckyj, JC; Franceschini, N; - view fewer (2021) Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci. Genome Medicine , 13 (1) , Article 74. 10.1186/s13073-021-00877-z.

Corpas, M; Beck, S; Glusman, G; Shabani, M; (2021) Editorial: Personal Genomes: Accessing, Sharing, and Interpretation. Frontiers in Genetics , 12 , Article 687584. 10.3389/fgene.2021.687584.

Dritsoula, A; Kislikova, M; Oomatia, A; Webster, AP; Beck, S; Ponticos, M; Lindsey, B; ... Caplin, B; + view all Dritsoula, A; Kislikova, M; Oomatia, A; Webster, AP; Beck, S; Ponticos, M; Lindsey, B; Norman, J; Wheeler, DC; Oates, T; Caplin, B; - view fewer (2021) Epigenome-wide methylation profile of chronic kidney disease-derived arterial DNA uncovers novel pathways in disease-associated cardiovascular pathology. Epigenetics , 16 (7) pp. 718-728. 10.1080/15592294.2020.1819666.

Gangoso, E; Southgate, B; Bradley, L; Rus, S; Galvez-Cancino, F; McGivern, N; Güç, E; ... Pollard, SM; + view all Gangoso, E; Southgate, B; Bradley, L; Rus, S; Galvez-Cancino, F; McGivern, N; Güç, E; Kapourani, C-A; Byron, A; Ferguson, KM; Alfazema, N; Morrison, G; Grant, V; Blin, C; Sou, I; Marques-Torrejon, MA; Conde, L; Parrinello, S; Herrero, J; Beck, S; Brandner, S; Brennan, PM; Bertone, P; Pollard, JW; Quezada, SA; Sproul, D; Frame, MC; Serrels, A; Pollard, SM; - view fewer (2021) Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion. Cell 10.1016/j.cell.2021.03.023. (In press).

Lyskjaer, I; De Noon, S; Tirabosco, R; Rocha, AM; Lindsay, D; Amary, F; Ye, H; ... Flanagan, AM; + view all Lyskjaer, I; De Noon, S; Tirabosco, R; Rocha, AM; Lindsay, D; Amary, F; Ye, H; Schrimpf, D; Stichel, D; Sill, M; Koelsche, C; Pillay, N; Von Deimling, A; Beck, S; Flanagan, AM; - view fewer (2021) DNA methylation-based profiling of bone and soft tissue tumours: a validation study of the 'DKFZ Sarcoma Classifier'. The Journal of Pathology: Clinical Research 10.1002/cjp2.215. (In press).

McErlean, P; Bell, CG; Hewitt, RJ; Busharat, Z; Ogger, PP; Ghai, P; Albers, GJ; ... Byrne, AJ; + view all McErlean, P; Bell, CG; Hewitt, RJ; Busharat, Z; Ogger, PP; Ghai, P; Albers, GJ; Calamita, E; Kingston, S; Molyneaux, PL; Beck, S; Lloyd, CM; Maher, TM; Byrne, AJ; - view fewer (2021) DNA Methylome Alterations are Associated with Airway Macrophage Differentiation and Phenotype During Lung Fibrosis. American Journal of Respiratory and Critical Care Medicine , 204 (8) pp. 954-966. 10.1164/rccm.202101-0004OC.

Smeeth, Demelza; Beck, Stephan; Karam, Elie G; Pluess, Michael; (2021) The role of epigenetics in psychological resilience. The Lancet Psychiatry , 8 (7) pp. 620-629. 10.1016/S2215-0366(20)30515-0.

Turati, VA; Guerra-Assunção, JA; Potter, NE; Gupta, R; Ecker, S; Daneviciute, A; Tarabichi, M; ... Enver, T; + view all Turati, VA; Guerra-Assunção, JA; Potter, NE; Gupta, R; Ecker, S; Daneviciute, A; Tarabichi, M; Webster, AP; Ding, C; May, G; James, C; Brown, J; Conde, L; Russell, LJ; Ancliff, P; Inglott, S; Cazzaniga, G; Biondi, A; Hall, GW; Lynch, M; Hubank, M; Macaulay, I; Beck, S; Van Loo, P; Jacobsen, SE; Greaves, M; Herrero, J; Enver, T; - view fewer (2021) Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia. Nature Cancer , 2 pp. 835-852. 10.1038/s43018-021-00219-3.

2020

AbdulJabbar, K; Raza, SEA; Rosenthal, R; Jamal-Hanjani, M; Veeriah, S; Akarca, A; Lund, T; ... Yuan, Y; + view all AbdulJabbar, K; Raza, SEA; Rosenthal, R; Jamal-Hanjani, M; Veeriah, S; Akarca, A; Lund, T; Moore, DA; Salgado, R; Al Bakir, M; Zapata, L; Hiley, CT; Officer, L; Sereno, M; Smith, CR; Loi, S; Hackshaw, A; Marafioti, T; Quezada, SA; McGranahan, N; Le Quesne, J; Swanton, C; Yuan, Y; - view fewer (2020) Geospatial immune variability illuminates differential evolution of lung adenocarcinoma. Nature Medicine , 26 pp. 1054-1062. 10.1038/s41591-020-0900-x.

Guerra-Assunção, JA; Conde, L; Moghul, I; Webster, AP; Ecker, S; Chervova, O; Chatzipantsiou, C; ... Herrero, J; + view all Guerra-Assunção, JA; Conde, L; Moghul, I; Webster, AP; Ecker, S; Chervova, O; Chatzipantsiou, C; Prieto, PP; Beck, S; Herrero, J; - view fewer (2020) GenomeChronicler: The Personal Genome Project UK Genomic Report Generator Pipeline. Frontiers in Genetics , 11 , Article 518644. 10.3389/fgene.2020.518644.

Litchfield, K; Stanislaw, S; Spain, L; Gallegos, LL; Rowan, A; Schnidrig, D; Rosenbaum, H; ... Turajlic, S; + view all Litchfield, K; Stanislaw, S; Spain, L; Gallegos, LL; Rowan, A; Schnidrig, D; Rosenbaum, H; Harle, A; Au, L; Hill, SM; Tippu, Z; Thomas, J; Thompson, L; Xu, H; Horswell, S; Barhoumi, A; Jones, C; Leith, KF; Burgess, DL; Watkins, TBK; Lim, E; Birkbak, NJ; Lamy, P; Nordentoft, I; Dyrskjøt, L; Pickering, L; Hazell, S; Jamal-Hanjani, M; PEACE Consortium; Larkin, J; Swanton, C; Alexander, NR; Turajlic, S; - view fewer (2020) Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue. Cell Reports , 31 (5) p. 107550. 10.1016/j.celrep.2020.107550.

López, S; Lim, EL; Horswell, S; Haase, K; Huebner, A; Dietzen, M; Mourikis, TP; ... McGranahan, N; + view all López, S; Lim, EL; Horswell, S; Haase, K; Huebner, A; Dietzen, M; Mourikis, TP; Watkins, TBK; Rowan, A; Dewhurst, SM; Birkbak, NJ; Wilson, GA; Van Loo, P; Jamal-Hanjani, M; TRACERx Consortium; Swanton, C; McGranahan, N; - view fewer (2020) Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution. Nature Genetics , 52 (3) pp. 283-293. 10.1038/s41588-020-0584-7.

Oka, A; Takagi, A; Komiyama, E; Yoshihara, N; Mano, S; Hosomichi, K; Suzuki, S; ... Ikeda, S; + view all Oka, A; Takagi, A; Komiyama, E; Yoshihara, N; Mano, S; Hosomichi, K; Suzuki, S; Haida, Y; Motosugi, N; Hatanaka, T; Kimura, M; Ueda, MT; Nakagawa, S; Miura, H; Ohtsuka, M; Tanaka, M; Komiyama, T; Otomo, A; Hadano, S; Mabuchi, T; Beck, S; Inoko, H; Ikeda, S; - view fewer (2020) Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss. EBioMedicine , 57 , Article 102810. 10.1016/j.ebiom.2020.102810.

Teschendorff, AE; Zhu, T; Breeze, CE; Beck, S; (2020) EPISCORE: cell type deconvolution of bulk tissue DNA methylomes from single-cell RNA-Seq data. Genome Biology , 21 , Article 221. 10.1186/s13059-020-02126-9.

Zheng, SC; Breeze, CE; Beck, S; Dong, D; Zhu, T; Ma, L; Ye, W; ... Teschendorff, AE; + view all Zheng, SC; Breeze, CE; Beck, S; Dong, D; Zhu, T; Ma, L; Ye, W; Zhang, G; Teschendorff, AE; - view fewer (2020) EpiDISH web server: Epigenetic Dissection of Intra-Sample-Heterogeneity with online GUI. Bioinformatics , 36 (6) pp. 1950-1951. 10.1093/bioinformatics/btz833.

2019

Bell, CG; Lowe, R; Adams, PD; Baccarelli, AA; Beck, S; Bell, JT; Christensen, BC; ... Rakyan, VK; + view all Bell, CG; Lowe, R; Adams, PD; Baccarelli, AA; Beck, S; Bell, JT; Christensen, BC; Gladyshev, VN; Heijmans, BT; Horvath, S; Ideker, T; Issa, J-PJ; Kelsey, KT; Marioni, RE; Reik, W; Relton, CL; Schalkwyk, LC; Teschendorff, AE; Wagner, W; Zhang, K; Rakyan, VK; - view fewer (2019) DNA methylation aging clocks: challenges and recommendations. Genome Biology , 20 , Article 249. 10.1186/s13059-019-1824-y.

Breeze, CE; Reynolds, AP; van Dongen, J; Dunham, I; Lazar, J; Neph, S; Vierstra, J; ... Beck, S; + view all Breeze, CE; Reynolds, AP; van Dongen, J; Dunham, I; Lazar, J; Neph, S; Vierstra, J; Bourque, G; Teschendorff, AE; Stamatoyannopoulos, JA; Beck, S; - view fewer (2019) eFORGE v2.0: updated analysis of cell type-specific signal in epigenomic data. Bioinformatics 10.1093/bioinformatics/btz456. (In press).

Chervova, O; Conde, L; Guerra-Assunção, JA; Moghul, I; Webster, AP; Berner, A; Larose Cadieux, E; ... Beck, S; + view all Chervova, O; Conde, L; Guerra-Assunção, JA; Moghul, I; Webster, AP; Berner, A; Larose Cadieux, E; Tian, Y; Voloshin, V; Jesus, TF; Hamoudi, R; Herrero, J; Beck, S; - view fewer (2019) The Personal Genome Project-UK, an open access resource of human multi-omics data. Scientific Data , 6 , Article 257. 10.1038/s41597-019-0205-4.

Conesa, A; Beck, S; (2019) Making multi-omics data accessible to researchers. [Editorial comment]. Scientific Data , 6 (1) , Article 251. 10.1038/s41597-019-0258-4.

Dyke, SOM; Saulnier, KM; Dupras, C; Webster, AP; Maschke, K; Rothstein, M; Siebert, R; ... Joly, Y; + view all Dyke, SOM; Saulnier, KM; Dupras, C; Webster, AP; Maschke, K; Rothstein, M; Siebert, R; Walter, J; Beck, S; Pastinen, T; Joly, Y; - view fewer (2019) Points-to-consider on the return of results in epigenetic research. Genome Medicine , 11 (1) , Article 31. 10.1186/s13073-019-0646-6.

Ecker, S; Beck, S; (2019) The epigenetic clock: a molecular crystal ball for human aging? Aging (Albany NY) , 11 (2) pp. 833-835. 10.18632/aging/101712.

Joshi, K; Robert de Massy, M; Ismail, M; Reading, JL; Uddin, I; Woolston, A; Hatipoglu, E; ... Chain, B; + view all Joshi, K; Robert de Massy, M; Ismail, M; Reading, JL; Uddin, I; Woolston, A; Hatipoglu, E; Oakes, T; Rosenthal, R; Peacock, T; Ronel, T; Noursadeghi, M; Turati, V; Furness, AJS; Georgiou, A; Wong, YNS; Ben Aissa, A; Werner Sunderland, M; Jamal-Hanjani, M; Veeriah, S; Birkbak, NJ; Wilson, GA; Hiley, CT; Ghorani, E; Guerra-Assunção, JA; Herrero, J; Enver, T; Hadrup, SR; Hackshaw, A; Peggs, KS; McGranahan, N; Swanton, C; TRACERx Consortium, .; Quezada, SA; Chain, B; - view fewer (2019) Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer. Nature Medicine , 25 pp. 1549-1559. 10.1038/s41591-019-0592-2.

Kular, L; Needhamsen, M; Adzemovic, MZ; Kramarova, T; Gomez-Cabrero, D; Ewing, E; Piket, E; ... Jagodic, M; + view all Kular, L; Needhamsen, M; Adzemovic, MZ; Kramarova, T; Gomez-Cabrero, D; Ewing, E; Piket, E; Tegnér, J; Beck, S; Piehl, F; Brundin, L; Jagodic, M; - view fewer (2019) Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis. Clinical Epigenetics , 11 (1) , Article 86. 10.1186/s13148-019-0678-1.

Marioni, RE; Suderman, M; Chen, BH; Horvath, S; Bandinelli, S; Morris, T; Beck, S; ... Hägg, S; + view all Marioni, RE; Suderman, M; Chen, BH; Horvath, S; Bandinelli, S; Morris, T; Beck, S; Ferrucci, L; Pedersen, NL; Relton, CL; Deary, IJ; Hägg, S; - view fewer (2019) Tracking the Epigenetic Clock Across the Human Life Course: A Meta-analysis of Longitudinal Cohort Data. The Journals of Gerontology: Series A , 74 (1) pp. 57-61. 10.1093/gerona/gly060.

Nguyen, HP; Stewart, S; Kukwikila, MN; Jones, SF; Offenbartl-Stiegert, D; Mao, S; Balasubramanian, S; ... Howorka, S; + view all Nguyen, HP; Stewart, S; Kukwikila, MN; Jones, SF; Offenbartl-Stiegert, D; Mao, S; Balasubramanian, S; Beck, S; Howorka, S; - view fewer (2019) A Photo‐responsive Small‐Molecule Approach for the Opto‐epigenetic Modulation of DNA Methylation. Angewandte Chemie: International Edition , 58 (20) pp. 6620-6624. 10.1002/anie.201901139.

Rosenthal, R; Cadieux, EL; Salgado, R; Bakir, MA; Moore, DA; Hiley, CT; Lund, T; ... TRACERx consortium; + view all Rosenthal, R; Cadieux, EL; Salgado, R; Bakir, MA; Moore, DA; Hiley, CT; Lund, T; Tanić, M; Reading, JL; Joshi, K; Henry, JY; Ghorani, E; Wilson, GA; Birkbak, NJ; Jamal-Hanjani, M; Veeriah, S; Szallasi, Z; Loi, S; Hellmann, MD; Feber, A; Chain, B; Herrero, J; Quezada, SA; Demeulemeester, J; Van Loo, P; Beck, S; McGranahan, N; Swanton, C; TRACERx consortium; - view fewer (2019) Neoantigen-directed immune escape in lung cancer evolution. Nature 10.1038/s41586-019-1032-7. (In press).

Saulnier, KM; Bujold, D; Dyke, SOM; Dupras, C; Beck, S; Bourque, G; Joly, Y; (2019) Benefits and barriers in the design of harmonized access agreements for international data sharing. Scientific Data , 6 , Article 297. 10.1038/s41597-019-0310-4.

Teixeira, VH; Pipinikas, CP; Pennycuick, A; Lee-Six, H; Chandrasekharan, D; Beane, J; Morris, TJ; ... Janes, SM; + view all Teixeira, VH; Pipinikas, CP; Pennycuick, A; Lee-Six, H; Chandrasekharan, D; Beane, J; Morris, TJ; Karpathakis, A; Feber, A; Breeze, CE; Ntolios, P; Hynds, RE; Falzon, M; Capitanio, A; Carroll, B; Durrenberger, PF; Hardavella, G; Brown, JM; Lynch, AG; Farmery, H; Paul, DS; Chambers, RC; McGranahan, N; Navani, N; Thakrar, RM; Swanton, C; Beck, S; George, PJ; Spira, A; Campbell, PJ; Thirlwell, C; Janes, SM; - view fewer (2019) Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions. Nature Medicine , 25 pp. 517-525. 10.1038/s41591-018-0323-0.

Zhou, L; Ng, HK; Drautz-Moses, DI; Schuster, SC; Beck, S; Kim, C; Chambers, JC; Zhou, L; Ng, HK; Drautz-Moses, DI; Schuster, SC; Beck, S; Kim, C; Chambers, JC; Loh, M; - view fewer (2019) Systematic evaluation of library preparation methods and sequencing platforms for high-throughput whole genome bisulfite sequencing. Scientific Reports , 9 , Article 10383. 10.1038/s41598-019-46875-5.

2018

Beck, S; (2018) Getting up close and personal with UK genomics and beyond. Genome Medicine , 10 (1) p. 38. 10.1186/s13073-018-0552-3.

Beck, S; Berner, AM; Bignell, G; Bond, M; Callanan, MJ; Chervova, O; Conde, L; ... Wood, JN; + view all Beck, S; Berner, AM; Bignell, G; Bond, M; Callanan, MJ; Chervova, O; Conde, L; Corpas, M; Ecker, S; Elliott, HR; Fioramonti, SA; Flanagan, AM; Gaentzsch, R; Graham, D; Gribbin, D; Guerra-Assuncao, JA; Hamoudi, R; Harding, V; Harrison, PL; Herrero, J; Hofmann, J; Jones, E; Khan, S; Kaye, J; Kerr, P; Libertini, E; Marks, L; McCormack, L; Moghul, I; Pontikos, N; Rajanayagam, S; Rana, K; Semega-Janneh, M; Smith, CP; Strom, L; Umur, S; Webster, AP; Williams, EH; Wint, K; Wood, JN; - view fewer (2018) Personal Genome Project UK (PGP-UK): a research and citizen science hybrid project in support of personalized medicine. BMC Medical Genomics , 11 , Article 108. 10.1186/s12920-018-0423-1.

Dyke, SOM; Linden, M; Lappalainen, I; De Argila, JR; Carey, K; Lloyd, D; Spalding, JD; ... Flicek, P; + view all Dyke, SOM; Linden, M; Lappalainen, I; De Argila, JR; Carey, K; Lloyd, D; Spalding, JD; Cabili, MN; Kerry, G; Foreman, J; Cutts, T; Shabani, M; Rodriguez, LL; Haeussler, M; Walsh, B; Jiang, X; Wang, S; Perrett, D; Boughtwood, T; Matern, A; Brookes, AJ; Cupak, M; Fiume, M; Pandya, R; Tulchinsky, I; Scollen, S; Törnroos, J; Das, S; Evans, AC; Malin, BA; Beck, S; Brenner, SE; Nyrönen, T; Blomberg, N; Firth, HV; Hurles, M; Philippakis, AA; Rätsch, G; Brudno, M; Boycott, KM; Rehm, HL; Baudis, M; Sherry, ST; Kato, K; Knoppers, BM; Baker, D; Flicek, P; - view fewer (2018) Registered access: authorizing data access. European Journal of Human Genetics , 26 pp. 1721-1731. 10.1038/s41431-018-0219-y.

Ecker, S; Pancaldi, V; Valencia, A; Beck, S; Paul, DS; (2018) Epigenetic and Transcriptional Variability Shape Phenotypic Plasticity. BioEssays , 40 (2) , Article 1700148. 10.1002/bies.201700148.

Frampton, D; Schwenzer, H; Marino, G; Butcher, LM; Pollara, G; Kriston-Vizi, J; Venturini, C; ... Fassati, A; + view all Frampton, D; Schwenzer, H; Marino, G; Butcher, LM; Pollara, G; Kriston-Vizi, J; Venturini, C; Austin, R; de Castro, KF; Ketteler, R; Chain, B; Goldstein, RA; Weiss, RA; Beck, S; Fassati, A; - view fewer (2018) Molecular Signatures of Regression of the Canine Transmissible Venereal Tumor. Cancer Cell , 33 (4) 620-633.e6. 10.1016/j.ccell.2018.03.003.

Hasenoehrl, C; Feuersinger, D; Sturm, EM; Bärnthaler, T; Heitzer, E; Graf, R; Grill, M; ... Schicho, R; + view all Hasenoehrl, C; Feuersinger, D; Sturm, EM; Bärnthaler, T; Heitzer, E; Graf, R; Grill, M; Pichler, M; Beck, S; Butcher, L; Thomas, D; Ferreirós, N; Schuligoi, R; Schweiger, C; Haybaeck, J; Schicho, R; - view fewer (2018) G protein-coupled receptor GPR55 promotes colorectal cancer and has opposing effects to cannabinoid receptor 1. International Journal of Cancer , 142 (1) pp. 121-132. 10.1002/ijc.31030.

Maher, GJ; Ralph, HK; Ding, Z; Koelling, N; Mlcochova, H; Giannoulatou, E; Dhami, P; ... Goriely, A; + view all Maher, GJ; Ralph, HK; Ding, Z; Koelling, N; Mlcochova, H; Giannoulatou, E; Dhami, P; Paul, DS; Stricker, SH; Beck, S; McVean, G; Wilkie, AO; Goriely, A; - view fewer (2018) Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes. Genome Research , 28 (12) pp. 1779-1790. 10.1101/gr.239186.118.

Marzi, SJ; Leung, SK; Ribarska, T; Hannon, E; Smith, AR; Pishva, E; Poschmann, J; ... Mill, J; + view all Marzi, SJ; Leung, SK; Ribarska, T; Hannon, E; Smith, AR; Pishva, E; Poschmann, J; Moore, K; Troakes, C; Al-Sarraj, S; Beck, S; Newman, S; Lunnon, K; Schalkwyk, LC; Mill, J; - view fewer (2018) A histone acetylome-wide association study of Alzheimer's disease identifies disease-associated H3K27ac differences in the entorhinal cortex. Nature Neuroscience , 21 pp. 1618-1627. 10.1038/s41593-018-0253-7.

Tanić, M; Krivokuća, A; Čavić, M; Mladenović, J; Plesinac Karapandžić, V; Beck, S; Radulović, S; ... Janković, R; + view all Tanić, M; Krivokuća, A; Čavić, M; Mladenović, J; Plesinac Karapandžić, V; Beck, S; Radulović, S; Susnjar, S; Janković, R; - view fewer (2018) Molecular signature of response to preoperative radiotherapy in locally advanced breast cancer. Radiation Oncology , 13 (1) , Article 193. 10.1186/s13014-018-1129-4.

Thurner, M; van de Bunt, M; Torres, JM; Mahajan, A; Nylander, V; Bennett, AJ; Gaulton, KJ; ... McCarthy, MI; + view all Thurner, M; van de Bunt, M; Torres, JM; Mahajan, A; Nylander, V; Bennett, AJ; Gaulton, KJ; Barrett, A; Burrows, C; Bell, CG; Lowe, R; Beck, S; Rakyan, VK; Gloyn, AL; McCarthy, MI; - view fewer (2018) Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci. eLife , 7 , Article e31977. 10.7554/eLife.31977.

Wang, Y; Karlsson, R; Lampa, E; Zhang, Q; Hedman, ÅK; Almgren, M; Almqvist, C; ... Hägg, S; + view all Wang, Y; Karlsson, R; Lampa, E; Zhang, Q; Hedman, ÅK; Almgren, M; Almqvist, C; McRae, AF; Marioni, RE; Ingelsson, E; Visscher, PM; Deary, IJ; Lind, L; Morris, T; Beck, S; Pedersen, NL; Hägg, S; - view fewer (2018) Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins. Epigenetics 10.1080/15592294.2018.1526028.

Webster, AP; Plant, D; Ecker, S; Zufferey, F; Bell, JT; Feber, A; Paul, DS; ... Worthington, J; + view all Webster, AP; Plant, D; Ecker, S; Zufferey, F; Bell, JT; Feber, A; Paul, DS; Beck, S; Barton, A; Williams, FMK; Worthington, J; - view fewer (2018) Increased DNA methylation variability in rheumatoid arthritis-discordant monozygotic twins. Genome Medicine , 10 (1) , Article 64. 10.1186/s13073-018-0575-9.

Zheng, S; Breeze, C; Beck, S; Teschendorff, AE; (2018) Identification of differentially methylated cell types in epigenome-wide association studies. Nature Methods , 15 1059 -1066. 10.1038/s41592-018-0213-x.

Zheng, SC; Webster, AP; Dong, D; Feber, A; Graham, DG; Sullivan, R; Jevons, S; ... Teschendorff, AE; + view all Zheng, SC; Webster, AP; Dong, D; Feber, A; Graham, DG; Sullivan, R; Jevons, S; Lovat, LB; Beck, S; Widschwendter, M; Teschendorff, AE; - view fewer (2018) A novel cell-type deconvolution algorithm reveals substantial contamination by immune cells in saliva, buccal and cervix. Epigenomics , 10 (7) pp. 925-940. 10.2217/epi-2018-0037.

2017

Barrett, JE; Feber, A; Herrero, J; Tanic, M; Wilson, GA; Swanton, C; Beck, S; (2017) Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection. BMC Bioinformatics , 18 , Article 354. 10.1186/s12859-017-1753-2.

Budin-Ljøsne, I; Teare, HJ; Kaye, J; Beck, S; Bentzen, HB; Caenazzo, L; Collett, C; ... Mascalzoni, D; + view all Budin-Ljøsne, I; Teare, HJ; Kaye, J; Beck, S; Bentzen, HB; Caenazzo, L; Collett, C; D'Abramo, F; Felzmann, H; Finlay, T; Javaid, MK; Jones, E; Katić, V; Simpson, A; Mascalzoni, D; - view fewer (2017) Dynamic Consent: a potential solution to some of the challenges of modern biomedical research. BMC Medical Ethics , 18 , Article 4. 10.1186/s12910-016-0162-9.

Butcher, LM; Beck, S; (2017) Nano-MeDIP-seq Methylome Analysis Using Low DNA Concentrations. Methods in Molecular Biology: Population Epigenetics , 1589 pp. 115-138. 10.1007/7651_2015_259.

Cheung, WA; Shao, X; Morin, A; Siroux, V; Kwan, T; Ge, B; Aissi, D; ... Grundberg, E; + view all Cheung, WA; Shao, X; Morin, A; Siroux, V; Kwan, T; Ge, B; Aissi, D; Chen, L; Vasquez, L; Allum, F; Guenard, F; Bouzigon, E; Simon, M-M; Boulier, E; Redensek, A; Watt, S; Datta, A; Clarke, L; Flicek, P; Mead, D; Paul, DS; Beck, S; Bourque, G; Lathrop, M; Tchernof, A; Vohl, M-C; Demenais, F; Pin, I; Downes, K; Stunnenberg, HG; Soranzo, N; Pastinen, T; Grundberg, E; - view fewer (2017) Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome. Genome Biology , 18 , Article 50. 10.1186/s13059-017-1173-7.

Ecker, S; Beck, S; (2017) Epigenetic variation taking center stage in immunological research. Epigenomics , 9 (4) pp. 375-378. 10.2217/epi-2017-0006.

Ecker, S; Chen, L; Pancaldi, V; Bagger, FO; Fernández, JM; Carrillo de Santa Pau, E; Juan, D; ... Paul, DS; + view all Ecker, S; Chen, L; Pancaldi, V; Bagger, FO; Fernández, JM; Carrillo de Santa Pau, E; Juan, D; Mann, AL; Watt, S; Casale, FP; Sidiropoulos, N; Rapin, N; Merkel, A; BLUEPRINT Consortium, .; Stunnenberg, HG; Stegle, O; Frontini, M; Downes, K; Pastinen, T; Kuijpers, TW; Rico, D; Valencia, A; Beck, S; Soranzo, N; Paul, DS; - view fewer (2017) Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types. Genome Biology , 18 , Article 18. 10.1186/s13059-017-1156-8.

Feber, A; Dhami, P; Dong, L; de Winter, P; Tan, WS; Martínez-Fernández, M; Paul, DS; ... Kelly, JD; + view all Feber, A; Dhami, P; Dong, L; de Winter, P; Tan, WS; Martínez-Fernández, M; Paul, DS; Hynes-Allen, A; Rezaee, S; Gurung, P; Rodney, S; Mehmood, A; Villacampa, F; de la Rosa, F; Jameson, C; Cheng, KK; Zeegers, MP; Bryan, RT; James, ND; Paramio, JM; Freeman, A; Beck, S; Kelly, JD; - view fewer (2017) UroMark - a urinary biomarker assay for the detection of bladder cancer. Clinical Epigenetics , 9 , Article 8. 10.1186/s13148-016-0303-5.

Karpathakis, A; Dibra, H; Pipinikas, C; Feber, A; Morris, T; Francis, JM; Oukrif, D; ... Thirlwell, C; + view all Karpathakis, A; Dibra, H; Pipinikas, C; Feber, A; Morris, T; Francis, JM; Oukrif, D; Mandair, D; Pericleous, M; Mohmaduvesh, M; Serra, S; Ogunbiyi, O; Novelli, M; Luong, TV; Asa, SL; Kulke, MH; Toumpanakis, C; Meyer, T; Caplin, M; Beck, S; Thirlwell, C; - view fewer (2017) Progressive epigenetic dysregulation in neuroendocrine tumour liver metastasis. Endocrine-Related Cancer , 24 (2) L21-L25. 10.1530/ERC-16-0419.

Kling, T; Wenger, A; Beck, S; Caren, H; (2017) Validation of the Methylation EPIC BeadChip for fresh-frozen and formalin-fixed paraffinembedded tumours. Clinical Epigenetics , 9 , Article 33. 10.1186/s13148-017-0333-7.

Oka, A; Asano, Y; Hasegawa, M; Fujimoto, M; Ishikawa, O; Kuwana, M; Kawaguchi, Y; ... Ihn, H; + view all Oka, A; Asano, Y; Hasegawa, M; Fujimoto, M; Ishikawa, O; Kuwana, M; Kawaguchi, Y; Yamamoto, T; Takahashi, H; Goto, D; Endo, H; Jinnin, M; Mano, S; Hosomichi, K; Mabuchi, T; Ueda, MT; Nakagawa, S; Beck, S; Bahram, S; Takehara, K; Sato, S; Ihn, H; - view fewer (2017) RXRB is a MHC-encoded susceptibility gene associated with anti-topoisomerase I antibody-positive systemic sclerosis. Journal of Investigative Dermatology , 137 (9) pp. 1878-1886. 10.1016/j.jid.2017.04.028.

Pan, S; Lai, H; Shen, Y; Breeze, C; Beck, S; Hong, T; Wang, C; Pan, S; Lai, H; Shen, Y; Breeze, C; Beck, S; Hong, T; Wang, C; Teschendorff, AE; - view fewer (2017) DNA methylome analysis reveals distinct epigenetic patterns of ascending aortic dissection and bicuspid aortic valve. Cardiovascular Research , 113 (6) pp. 692-704. 10.1093/cvr/cvx050.

Schütte, M; Risch, T; Abdavi-Azar, N; Boehnke, K; Schumacher, D; Keil, M; Yildiriman, R; ... Yaspo, ML; + view all Schütte, M; Risch, T; Abdavi-Azar, N; Boehnke, K; Schumacher, D; Keil, M; Yildiriman, R; Jandrasits, C; Borodina, T; Amstislavskiy, V; Worth, CL; Schweiger, C; Liebs, S; Lange, M; Warnatz, HJ; Butcher, LM; Barrett, JE; Sultan, M; Wierling, C; Golob-Schwarzl, N; Lax, S; Uranitsch, S; Becker, M; Welte, Y; Regan, JL; Silvestrov, M; Kehler, I; Fusi, A; Kessler, T; Herwig, R; Landegren, U; Wienke, D; Nilsson, M; Velasco, JA; Garin-Chesa, P; Reinhard, C; Beck, S; Schäfer, R; Regenbrecht, CR; Henderson, D; Lange, B; Haybaeck, J; Keilholz, U; Hoffmann, J; Lehrach, H; Yaspo, ML; - view fewer (2017) Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors. Nature Communications , 8 , Article 14262. 10.1038/ncomms14262.

Stricker, SH; Koferle, A; Beck, S; (2017) From profiles to function in epigenomics. [Review]. Nature Reviews Genetics , 18 (1) pp. 51-66. 10.1038/nrg.2016.138.

Szlosarek, PW; Steele, JP; Nolan, L; Gilligan, D; Taylor, P; Spicer, J; Lind, M; ... Hackshaw, A; + view all Szlosarek, PW; Steele, JP; Nolan, L; Gilligan, D; Taylor, P; Spicer, J; Lind, M; Mitra, S; Shamash, J; Phillips, MM; Luong, P; Payne, S; Hillman, P; Ellis, S; Szyszko, T; Dancey, G; Butcher, L; Beck, S; Avril, NE; Thomson, J; Johnston, A; Tomsa, M; Lawrence, C; Schmid, P; Crook, T; Wu, B-W; Bomalaski, JS; Lemoine, N; Sheaff, MT; Rudd, RM; Fennell, D; Hackshaw, A; - view fewer (2017) Arginine Deprivation With Pegylated Arginine Deiminase in Patients With Argininosuccinate Synthetase 1-Deficient Malignant Pleural Mesothelioma A Randomized Clinical Trial. JAMA Oncology , 3 (1) pp. 58-66. 10.1001/jamaoncol.2016.3049.

Tanic, M; Beck, S; (2017) Cell-free DNA: Treasure trove for cancer medicine. Nature Materials , 16 (11) pp. 1056-1057. 10.1038/nmat5019.

Tanic, M; Beck, S; (2017) Epigenome-wide association studies for cancer biomarker discovery in circulating cell-free DNA: technical advances and challenges. Current Opinion in Genetics and Development , 42 pp. 48-55. 10.1016/j.gde.2017.01.017.

Teschendorff, AE; Breeze, CE; Zheng, SC; Beck, S; (2017) A comparison of reference-based algorithms for correcting cell-type heterogeneity in Epigenome-Wide Association Studies. BMC Bioinformatics , 18 (1) , Article 105. 10.1186/s12859-017-1511-5.

Tian, Y; Morris, TJ; Webster, AP; Yang, Z; Beck, S; Feber, A; Teschendorff, AE; (2017) ChAMP: Updated Methylation Analysis Pipeline for Illumina BeadChips. Bioinformatics , 33 (24) pp. 3982-3984. 10.1093/bioinformatics/btx513.

Zheng, SC; Beck, S; Jaffe, AE; Koestler, DC; Hansen, KD; Houseman, AE; Irizarry, RA; Zheng, SC; Beck, S; Jaffe, AE; Koestler, DC; Hansen, KD; Houseman, AE; Irizarry, RA; Teschendorff, AE; - view fewer (2017) Correcting for cell-type heterogeneity in epigenome-wide association studies: revisiting previous analyses. Nature Methods , 14 (3) pp. 216-217. 10.1038/nmeth.4187.

2016

Astle, WJ; Elding, H; Jiang, T; Allen, D; Ruklisa, D; Mann, AL; Mead, D; ... Soranzo, N; + view all Astle, WJ; Elding, H; Jiang, T; Allen, D; Ruklisa, D; Mann, AL; Mead, D; Bouman, H; Riveros-Mckay, F; Kostadima, MA; Lambourne, JJ; Sivapalaratnam, S; Downes, K; Kundu, K; Bomba, L; Berentsen, K; Bradley, JR; Daugherty, LC; Delaneau, O; Freson, K; Garner, SF; Grassi, L; Guerrero, J; Haimel, M; Janssen-Megens, EM; Kaan, A; Kamat, M; Kim, B; Mandoli, A; Marchini, J; Martens, JHA; Meacham, S; Megy, K; O'Connell, J; Petersen, R; Sharifi, N; Sheard, SM; Staley, JR; Tuna, S; van der Ent, M; Walter, K; Wang, S-Y; Wheeler, E; Wilder, SP; Iotchkova, V; Moore, C; Sambrook, J; Stunnenberg, HG; Di Angelantonio, E; Kaptoge, S; Kuijpers, TW; Carrillo-de-Santa-Pau, E; Juan, D; Rico, D; Valencia, A; Chen, L; Ge, B; Vasquez, L; Kwan, T; Garrido-Martin, D; Watt, S; Yang, Y; Guigo, R; Beck, S; Paul, DS; Pastinen, T; Bujold, D; Bourque, G; Frontini, M; Danesh, J; Roberts, DJ; Ouwehand, WH; Butterworth, AS; Soranzo, N; - view fewer (2016) The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Cell , 167 (5) pp. 1415-1429. 10.1016/j.cell.2016.10.042.

Bartlett, TE; Chindera, K; McDermott, J; Breeze, CE; Cooke, WR; Jones, A; Reisel, D; ... Widschwendter, M; + view all Bartlett, TE; Chindera, K; McDermott, J; Breeze, CE; Cooke, WR; Jones, A; Reisel, D; Karegodar, ST; Arora, R; Beck, S; Menon, U; Dubeau, L; Widschwendter, M; - view fewer (2016) Epigenetic reprogramming of fallopian tube fimbriae in BRCA mutation carriers defines early ovarian cancer evolution. Nature Communications , 7 , Article ARTN 116. 10.1038/ncomms11620.

Bock, C; Halbritter, F; Carmona, FJ; Tierling, S; Datlinger, P; Assenov, Y; Berdasco, M; ... Zhang, K; + view all Bock, C; Halbritter, F; Carmona, FJ; Tierling, S; Datlinger, P; Assenov, Y; Berdasco, M; Bergmann, AK; Booher, K; Busato, F; Campan, M; Dahl, C; Dahmcke, CM; Diep, D; Fernandez, AF; Gerhauser, C; Haake, A; Heilmann, K; Holcomb, T; Hussmann, D; Ito, M; Klaever, R; Kreutz, M; Kulis, M; Lopez, V; Nair, SS; Paul, DS; Plongthongkum, N; Qu, W; Queiros, AC; Reinicke, F; Sauter, G; Schlomm, T; Statham, A; Stirzaker, C; Strogantsev, R; Urdinguio, RG; Walter, K; Weichenhan, D; Weisenberger, DJ; Beck, S; Clark, SJ; Esteller, M; Ferguson-Smith, AC; Fraga, MF; Guldberg, P; Hansen, LL; Laird, PW; Martin-Subero, JI; Nygren, AOH; Peist, R; Plass, C; Shames, DS; Siebert, R; Sun, X; Tost, J; Walter, J; Zhang, K; - view fewer (2016) Quantitative comparison of DNA methylation assays for biomarker development and clinical applications. NATURE BIOTECHNOLOGY , 34 (7) pp. 726-737. 10.1038/nbt.3605.

Breeze, CE; Paul, DS; van Dongen, J; Butcher, LM; Ambrose, JC; Barrett, JE; Lowe, R; ... Beck, S; + view all Breeze, CE; Paul, DS; van Dongen, J; Butcher, LM; Ambrose, JC; Barrett, JE; Lowe, R; Rakyan, VK; Iotchkova, V; Frontini, M; Downes, K; Ouwehand, WH; Laperle, J; Jacques, PÉ; Bourque, G; Bergmann, AK; Siebert, R; Vellenga, E; Saeed, S; Matarese, F; Martens, JH; Stunnenberg, HG; Teschendorff, AE; Herrero, J; Birney, E; Dunham, I; Beck, S; - view fewer (2016) eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data. Cell Reports , 17 (8) pp. 2137-2150. 10.1016/j.celrep.2016.10.059.

Butcher, LM; Ito, M; Brimpari, M; Morris, TJ; Soares, FA; Ährlund-Richter, L; Carey, N; ... Beck, S; + view all Butcher, LM; Ito, M; Brimpari, M; Morris, TJ; Soares, FA; Ährlund-Richter, L; Carey, N; Vallier, L; Ferguson-Smith, AC; Beck, S; - view fewer (2016) Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells. Nature Communications , 7 , Article 10458. 10.1038/ncomms10458.

Chen, L; Ge, B; Casale, FP; Vasquez, L; Kwan, T; Garrido-Martín, D; Watt, S; ... Soranzo, N; + view all Chen, L; Ge, B; Casale, FP; Vasquez, L; Kwan, T; Garrido-Martín, D; Watt, S; Yan, Y; Kundu, K; Ecker, S; Datta, A; Richardson, D; Burden, F; Mead, D; Mann, AL; Fernandez, JM; Rowlston, S; Wilder, SP; Farrow, S; Shao, X; Lambourne, JJ; Redensek, A; Albers, CA; Amstislavskiy, V; Ashford, S; Berentsen, K; Bomba, L; Bourque, G; Bujold, D; Busche, S; Caron, M; Chen, SH; Cheung, W; Delaneau, O; Dermitzakis, ET; Elding, H; Colgiu, I; Bagger, FO; Flicek, P; Habibi, E; Iotchkova, V; Janssen-Megens, E; Kim, B; Lehrach, H; Lowy, E; Mandoli, A; Matarese, F; Maurano, MT; Morris, JA; Pancaldi, V; Pourfarzad, F; Rehnstrom, K; Rendon, A; Risch, T; Sharifi, N; Simon, MM; Sultan, M; Valencia, A; Walter, K; Wang, SY; Frontini, M; Antonarakis, SE; Clarke, L; Yaspo, ML; Beck, S; Guigo, R; Rico, D; Martens, JH; Ouwehand, WH; Kuijpers, TW; Paul, DS; Stunnenberg, HG; Stegle, O; Downes, K; Pastinen, T; Soranzo, N; - view fewer (2016) Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells. Cell , 167 (5) 1398-1414.e24. 10.1016/j.cell.2016.10.026.

Chen, Y; Breeze, CE; Zhen, S; Beck, S; Teschendorff, AE; (2016) Tissue-independent and tissue-specific patterns of DNA methylation alteration in cancer. Epigenetics & Chromatin , 9 , Article 10. 10.1186/s13072-016-0058-4.

Feber, A; Worth, DC; Chakravarthy, A; de Winter, P; Shah, K; Arya, M; Saqib, M; ... Kelly, JD; + view all Feber, A; Worth, DC; Chakravarthy, A; de Winter, P; Shah, K; Arya, M; Saqib, M; Nigam, R; Malone, PR; Tan, WS; Rodney, S; Freeman, A; Jameson, C; Wilson, GA; Powles, T; Beck, S; Fenton, T; Sharp, TV; Muneer, A; Kelly, JD; - view fewer (2016) CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma. Cancer Research , 76 (16) pp. 4720-4727. 10.1158/0008-5472.CAN-15-3134.

Koeferle, A; Worf, K; Breunig, C; Baumann, V; Herrero, J; Wiesbeck, M; Hutter, LH; ... Stricker, SH; + view all Koeferle, A; Worf, K; Breunig, C; Baumann, V; Herrero, J; Wiesbeck, M; Hutter, LH; Goetz, M; Fuchs, C; Beck, S; Stricker, SH; - view fewer (2016) CORALINA: a universal method for the generation of gRNA libraries for CRISPR-based screening. BMC Genomics , 17 , Article 917. 10.1186/s12864-016-3268-z.

Libertini, E; Heath, SC; Hamoudi, RA; Gut, M; Ziller, MJ; Czyz, A; Ruotti, V; ... Beck, S; + view all Libertini, E; Heath, SC; Hamoudi, RA; Gut, M; Ziller, MJ; Czyz, A; Ruotti, V; Stunnenberg, HG; Frontini, M; Ouwehand, WH; Meissner, A; Gut, IG; Beck, S; - view fewer (2016) Information recovery from low coverage whole-genome bisulfite sequencing. Nature Communications , 7 , Article 11306. 10.1038/ncomms11306.

Libertini, E; Heath, SC; Hamoudi, RA; Gut, M; Ziller, MJ; Herrero, J; Czyz, A; ... Beck, S; + view all Libertini, E; Heath, SC; Hamoudi, RA; Gut, M; Ziller, MJ; Herrero, J; Czyz, A; Ruotti, V; Stunnenberg, HG; Frontini, M; Ouwehand, WH; Meissner, A; Gut, IG; Beck, S; - view fewer (2016) Saturation analysis for whole-genome bisulfite sequencing data. [Letter]. Nature Biotechnology , 34 (7) pp. 691-693. 10.1038/nbt.3524.

Olsson, M; Beck, S; Kogner, P; Martinsson, T; Carén, H; (2016) Genome-wide methylation profiling identifies novel methylated genes in neuroblastoma tumors. Epigenetics pp. 1-11. 10.1080/15592294.2016.1138195.

Pataillot-Meakin, T; Pillay, N; Beck, S; (2016) 3-methylcytosine in cancer: an underappreciated methyl lesion? Epigenomics , 8 (4) pp. 451-454. 10.2217/epi.15.121.

Paul, DS; Teschendorff, AE; Dang, MA; Lowe, R; Hawa, MI; Ecker, S; Beyan, H; ... Leslie, RD; + view all Paul, DS; Teschendorff, AE; Dang, MA; Lowe, R; Hawa, MI; Ecker, S; Beyan, H; Cunningham, S; Fouts, AR; Ramelius, A; Burden, F; Farrow, S; Rowlston, S; Rehnstrom, K; Frontini, M; Downes, K; Busche, S; Cheung, WA; Ge, B; Simon, MM; Bujold, D; Kwan, T; Bourque, G; Datta, A; Lowy, E; Clarke, L; Flicek, P; Libertini, E; Heath, S; Gut, M; Gut, IG; Ouwehand, WH; Pastinen, T; Soranzo, N; Hofer, SE; Karges, B; Meissner, T; Boehm, BO; Cilio, C; Elding Larsson, H; Lernmark, Å; Steck, AK; Rakyan, VK; Beck, S; Leslie, RD; - view fewer (2016) Increased DNA methylation variability in type 1 diabetes across three immune effector cell types. Nature Communications , 7 , Article 13555. 10.1038/ncomms13555.

Stunnenberg, HG; Abrignani, S; Adams, D; de Almeida, M; Altucci, L; Amin, V; Amit, I; ... Kim, SC; + view all Stunnenberg, HG; Abrignani, S; Adams, D; de Almeida, M; Altucci, L; Amin, V; Amit, I; Antonarakis, SE; Aparicio, S; Arima, T; Arrigoni, L; Arts, R; Asnafi, V; Badosa, ME; Bae, JB; Bassler, K; Beck, S; Berkman, B; Bernstein, BE; Bilenky, M; Bird, A; Bock, C; Boehm, B; Bourque, G; Breeze, CE; Brors, B; Bujold, D; Burren, O; Bussemakers, MJ; Butterworth, A; Campo, E; Carrillo-de-Santa-Pau, E; Chadwick, L; Chan, KM; Chen, W; Cheung, TH; Chiapperino, L; Choi, NH; Chung, HR; Clarke, L; Connors, JM; Cronet, P; Danesh, J; Dermitzakis, M; Drewes, G; Durek, P; Dyke, S; Dylag, T; Eaves, CJ; Ebert, P; Eils, R; Eils, J; Ennis, CA; Enver, T; Feingold, EA; Felder, B; Ferguson-Smith, A; Fitzgibbon, J; Flicek, P; Foo, RSY; Fraser, P; Frontini, M; Furlong, E; Gakkhar, S; Gasparoni, N; Gasparoni, G; Geschwind, DH; Glažar, P; Graf, T; Grosveld, F; Guan, XY; Guigo, R; Gut, IG; Hamann, A; Han, BG; Harris, RA; Heath, S; Helin, K; Hengstler, JG; Heravi-Moussavi, A; Herrup, K; Hill, S; Hilton, JA; Hitz, BC; Horsthemke, B; Hu, M; Hwang, JY; Ip, NY; Ito, T; Javierre, BM; Jenko, S; Jenuwein, T; Joly, Y; Jones, SJM; Kanai, Y; Kang, HG; Karsan, A; Kiemer, AK; Kim, SC; - view fewer (2016) The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery. Cell , 167 (5) pp. 1145-1149. 10.1016/j.cell.2016.11.007.

Teschendorff, AE; Zheng, SC; Feber, A; Yang, Z; Beck, S; Widschwendter, M; (2016) The multi-omic landscape of transcription factor inactivation in cancer. Genome Medicine , 8 , Article 89. 10.1186/s13073-016-0342-8.

Van Dongen, J; Nivard, MG; Willemsen, G; Hottenga, JJ; Helmer, Q; Dolan, CV; Ehli, EA; ... Boomsma, DI; + view all Van Dongen, J; Nivard, MG; Willemsen, G; Hottenga, JJ; Helmer, Q; Dolan, CV; Ehli, EA; Davies, GE; van Iterson, M; Breeze, CE; Beck, S; BIOS Consortium; Suchiman, HE; Jansen, R; van Meurs, JB; Heijmans, BT; Slagboom, PE; Boomsma, DI; - view fewer (2016) Genetic and environmental influences interact with age and sex in shaping the human methylome. Nature Communications , 7 , Article 11115. 10.1038/ncomms11115.

Yang, Z; Wong, A; Kuh, D; Paul, DS; Rakyan, VK; Leslie, RD; Zheng, SC; ... Teschendorff, AE; + view all Yang, Z; Wong, A; Kuh, D; Paul, DS; Rakyan, VK; Leslie, RD; Zheng, SC; Widschwendter, M; Beck, S; Teschendorff, AE; - view fewer (2016) Correlation of an epigenetic mitotic clock with cancer risk. GENOME BIOLOGY , 17 (ARTN 205) 10.1186/s13059-016-1064-3.

2015

Butcher, LM; Beck, S; (2015) Probe Lasso: a novel method to rope in differentially methylated regions with 450K DNA methylation data. Methods , 72 21 - 28. 10.1016/j.ymeth.2014.10.036.

Feber, A; Arya, M; De Winter, P; Saqib, M; Nigam, R; Malone, PR; Tan, WS; ... Kelly, JD; + view all Feber, A; Arya, M; De Winter, P; Saqib, M; Nigam, R; Malone, PR; Tan, WS; Rodney, S; Lechner, M; Freeman, A; Jameson, C; Muneer, A; Beck, S; Kelly, JD; - view fewer (2015) Epigenetics Markers of Metastasis and HPV-Induced Tumorigenesis in Penile Cancer. Clinical Cancer Research , 21 (5) pp. 1196-1206. 10.1158/1078-0432.CCR-14-1656.

Karpathakis, A; (2015) Molecular profiling of gastrointestinal neuroendocrine tumours. Doctoral thesis , UCL (University College London).

Morris, TJ; Beck, S; (2015) Analysis pipelines and packages for Infinium HumanMethylation450 BeadChip (450k) data. Methods , 72 3 - 8. 10.1016/j.ymeth.2014.08.011.

Paul, DS; Jones, A; Sellar, RS; Mayor, NP; Feber, A; Webster, AP; Afonso, N; ... Beck, S; + view all Paul, DS; Jones, A; Sellar, RS; Mayor, NP; Feber, A; Webster, AP; Afonso, N; Sergeant, R; Szydlo, RM; Apperley, JF; Widschwendter, M; Mackinnon, S; Marsh, SG; Madrigal, JA; Rakyan, VK; Peggs, KS; Beck, S; - view fewer (2015) A donor-specific epigenetic classifier for acute graft-versus-host disease severity in hematopoietic stem cell transplantation. Genome Medicine , 7 (1) , Article 128. 10.1186/s13073-015-0246-z.

Pipinikas, C; Dibra, H; Karpathakis, A; Feber, A; Novelli, M; Oukrif, D; Fusai, G; ... Thirlwell, C; + view all Pipinikas, C; Dibra, H; Karpathakis, A; Feber, A; Novelli, M; Oukrif, D; Fusai, G; Valente, R; Caplin, M; Meyer, T; Teschendorff, A; Bell, C; Morris, T; Salomoni, P; Luong, TV; Davidson, B; Beck, S; Thirlwell, C; - view fewer (2015) Epigenetic dysregulation and poorer prognosis in DAXX-deficient pancreatic neuroendocrine tumours. [Letter]. Endocrine-Related Cancer , 22 (3) L13-L18. 10.1530/ERC-15-0108.

2014

Bell, CG; Wilson, GA; Beck, S; (2014) Human-specific CpG 'beacons' identify human-specific prefrontal cortex H3K4me3 chromatin peaks. Epigenomics , 6 (1) 21 - 31. 10.2217/epi.13.74.

Charlton, J; Williams, RD; Weeks, M; Sebire, NJ; Popov, S; Vujanic, G; Mifsud, W; ... Pritchard-Jones, K; + view all Charlton, J; Williams, RD; Weeks, M; Sebire, NJ; Popov, S; Vujanic, G; Mifsud, W; Alcaide-German, M; Butcher, LM; Beck, S; Pritchard-Jones, K; - view fewer (2014) Methylome analysis identifies a Wilms tumor epigenetic biomarker detectable in blood. Genome Biology , 15 , Article 434. 10.1186/s13059-014-0434-y.

Feber, A; Guilhamon, P; Lechner, M; Fenton, T; Wilson, GA; Thirlwell, C; Morris, TJ; ... Beck, S; + view all Feber, A; Guilhamon, P; Lechner, M; Fenton, T; Wilson, GA; Thirlwell, C; Morris, TJ; Flanagan, AM; Teschendorff, AE; Kelly, JD; Beck, S; - view fewer (2014) Using high-density DNA methylation arrays to profile copy number alterations. Genome Biol , 15 (2) , Article R30. 10.1186/gb-2014-15-2-r30.

Guilhamon, P; Butcher, LM; Presneau, N; Wilson, GA; Feber, A; Paul, DS; Schütte, M; ... Beck, S; + view all Guilhamon, P; Butcher, LM; Presneau, N; Wilson, GA; Feber, A; Paul, DS; Schütte, M; Haybaeck, J; Keilholz, U; Hoffman, J; Ross, MT; Flanagan, AM; Beck, S; - view fewer (2014) Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics. Genome Med , 6 (12) , Article 116. 10.1186/s13073-014-0116-0.

Paul, DS; Beck, S; (2014) Advances in epigenome-wide association studies for common diseases. Trends in Molecular Medicine , 20 (10) pp. 541-543. 10.1016/j.molmed.2014.07.002.

Paul, DS; Guilhamon, P; Karpathakis, A; Butcher, LM; Thirlwell, C; Feber, A; Beck, S; (2014) Assessment of RainDrop BS-seq as a method for large-scale, targeted bisulfite sequencing. Epigenetics , 9 (5) pp. 678-684. 10.4161/epi.28041.

Salomonsen, J; Chattaway, JA; Chan, AC; Parker, A; Huguet, S; Marston, DA; Rogers, SL; ... Kaufman, J; + view all Salomonsen, J; Chattaway, JA; Chan, AC; Parker, A; Huguet, S; Marston, DA; Rogers, SL; Wu, Z; Smith, AL; Staines, K; Butter, C; Riegert, P; Vainio, O; Nielsen, L; Kaspers, B; Griffin, DK; Yang, F; Zoorob, R; Guillemot, F; Auffray, C; Beck, S; Skjødt, K; Kaufman, J; - view fewer (2014) Sequence of a Complete Chicken BG Haplotype Shows Dynamic Expansion and Contraction of Two Gene Lineages with Particular Expression Patterns. PLoS Genetics , 10 (6) , Article e1004417. 10.1371/journal.pgen.1004417.

Stewart, SK; Morris, TJ; Guilhamon, P; Bulstrode, H; Bachman, M; Balasubramanian, S; Beck, S; (2014) oxBS-450K: A method for analysing hydroxymethylation using 450K BeadChips. Methods , 72 pp. 9-15. 10.1016/j.ymeth.2014.08.009.

Swanton, C; Beck, SA; (2014) Epigenetic noise fuels cancer evolution. Cancer Cell , 26 (6) pp. 775-776. 10.1016/j.ccell.2014.11.003.

Teschendorff, AE; Liu, X; Caren, H; Pollard, SM; Beck, S; Widschwendter, M; Chen, L; (2014) The dynamics of DNA methylation covariation patterns in carcinogenesis. PLoS Comput Biol , 10 (7) , Article e1003709. 10.1371/journal.pcbi.1003709.

Wilson, GA; Butcher, LM; Foster, HR; Feber, A; Roos, C; Walter, L; Woszczek, G; ... Bell, CG; + view all Wilson, GA; Butcher, LM; Foster, HR; Feber, A; Roos, C; Walter, L; Woszczek, G; Beck, S; Bell, CG; - view fewer (2014) Human-specific epigenetic variation in the immunological Leukotriene B4 Receptor (LTB4R/BLT1) implicated in common inflammatory diseases. Genome Med , 6 (3) , Article 19. 10.1186/gm536.

2013

Guilhamon, P; Eskandarpour, M; Halai, D; Wilson, GA; Feber, A; Teschendorff, AE; Gomez, V; ... Beck, S; + view all Guilhamon, P; Eskandarpour, M; Halai, D; Wilson, GA; Feber, A; Teschendorff, AE; Gomez, V; Hergovich, A; Tirabosco, R; Fernanda Amary, M; Baumhoer, D; Jundt, G; Ross, MT; Flanagan, AM; Beck, S; - view fewer (2013) Meta-analysis of IDH-mutant cancers identifies EBF1 as an interaction partner for TET2. Nature Communications , 4 , Article 2166. 10.1038/ncomms3166.

Lechner, M; Fenton, T; West, J; Wilson, G; Feber, A; Henderson, S; Thirlwell, C; ... Beck, S; + view all Lechner, M; Fenton, T; West, J; Wilson, G; Feber, A; Henderson, S; Thirlwell, C; Dibra, HK; Jay, A; Butcher, L; Chakravarthy, AR; Gratrix, F; Patel, N; Vaz, F; O'Flynn, P; Kalavrezos, N; Teschendorff, AE; Boshoff, C; Beck, S; - view fewer (2013) Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma. Genome Medicine , 5 (2) p. 15. 10.1186/gm419.

Lechner, M; Frampton, G; Fenton, T; Feber, A; Palmer, G; Jay, A; Pillay, N; ... Boshoff, C; + view all Lechner, M; Frampton, G; Fenton, T; Feber, A; Palmer, G; Jay, A; Pillay, N; Forster, M; Cronin, MT; Lipson, D; Miller, VA; Brennan, TA; Henderson, S; Vaz, F; O 8217 Flynn, P; Kalavrezos, N; Yelenski, R; Beck, S; Stephens, PJ; Boshoff, C; - view fewer (2013) Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors. Genome Medicine , 5 , Article 49. 10.1186/gm453.

Paul, DS; Soranzo, N; Beck, S; (2013) Functional interpretation of non-coding sequence variation: Concepts and challenges. Bioessays , 36 (2) pp. 191-199. 10.1002/bies.201300126.

Taiwo, O; Wilson, GA; Emmett, W; Morris, T; Bonnet, D; Schuster, E; Adejumo, T; ... Pearce, DJ; + view all Taiwo, O; Wilson, GA; Emmett, W; Morris, T; Bonnet, D; Schuster, E; Adejumo, T; Beck, S; Pearce, DJ; - view fewer (2013) DNA methylation analysis of murine hematohematopoietic side population cells during aging. Epigenetics , 8 (10) pp. 1114-1122. 10.4161/epi.26017.

Teschendorff, AE; Marabita, F; Lechner, M; Bartlett, T; Tegner, J; Gomez-Cabrero, D; Beck, S; (2013) A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data. Bioinformatics , 29 (2) 189 - 196. 10.1093/bioinformatics/bts680.

Teschendorff, AE; West, J; Beck, S; (2013) Age-associated epigenetic drift: implications, and a case of epigenetic thrift? Human Molecular Genetics , 22 (R1) R7-R15. 10.1093/hmg/ddt375.

West, J; Beck, S; Wang, X; Teschendorff, AE; (2013) An integrative network algorithm identifies age-associated differential methylation interactome hotspots targeting stem-cell differentiation pathways. Scientific Reports , 3 , Article 1630. 10.1038/srep01630.

Wilson, GA; Lechner, M; Köferle, A; Carén, H; Butcher, LM; Feber, A; Fenton, T; ... Beck, S; + view all Wilson, GA; Lechner, M; Köferle, A; Carén, H; Butcher, LM; Feber, A; Fenton, T; Jay, A; Boshoff, C; Beck, S; - view fewer (2013) Integrated virus-host methylome analysis in head and neck squamous cell carcinoma. Epigenetics , 8 (9) pp. 953-961. 10.4161/epi.25614.

2012

Bell, CG; Wilson, GA; Butcher, LM; Roos, C; Walter, L; Beck, S; (2012) Human-specific CpG "beacons" identify loci associated with human-specific traits and disease. Epigenetics , 7 (10) 1188 - 1199. 10.4161/epi.22127.

Häsler, R; Feng, Z; Bäckdahl, L; Spehlmann, ME; Franke, A; Teschendorff, A; Rakyan, VK; ... Rosenstiel, P; + view all Häsler, R; Feng, Z; Bäckdahl, L; Spehlmann, ME; Franke, A; Teschendorff, A; Rakyan, VK; Down, TA; Wilson, GA; Feber, A; Beck, S; Schreiber, S; Rosenstiel, P; - view fewer (2012) A functional methylome map of ulcerative colitis. Genome Research , 22 (11) 2130 -2137. 10.1101/gr.138347.112.

2011

Cortese, R; Lewin, J; Backdahl, L; Krispin, M; Wasserkort, R; Eckhardt, F; Beck, S; (2011) Genome-Wide Screen for Differential DNA Methylation Associated with Neural Cell Differentiation in Mouse. PLOS ONE , 6 (10) , Article e26002. 10.1371/journal.pone.0026002.

Rakyan, VK; Beyan, H; Down, TA; Hawa, MI; Maslau, S; Aden, D; Daunay, A; ... Leslie, RD; + view all Rakyan, VK; Beyan, H; Down, TA; Hawa, MI; Maslau, S; Aden, D; Daunay, A; Busato, F; Mein, CA; Manfras, B; Dias, KRM; Bell, CG; Tost, J; Boehm, BO; Beck, S; Leslie, RD; - view fewer (2011) Identification of Type 1 Diabetes-Associated DNA Methylation Variable Positions That Precede Disease Diagnosis. PLOS GENET , 7 (9) , Article e1002300. 10.1371/journal.pgen.1002300.

Siddle, HV; Deakin, JE; Coggill, P; Whilming, L; Harrow, J; Kaufman, J; Beck, S; Siddle, HV; Deakin, JE; Coggill, P; Whilming, L; Harrow, J; Kaufman, J; Beck, S; Belov, K; - view fewer (2011) The tammar wallaby major histocompatibility complex shows evidence of past genomic instability. BMC GENOMICS , 12 , Article 421. 10.1186/1471-2164-12-421.

2010

Bell, CG; Finer, S; Lindgren, CM; Wilson, GA; Rakyan, VK; Teschendorff, AE; Akan, P; ... Int Type 2 Diabet 1q Consortium; + view all Bell, CG; Finer, S; Lindgren, CM; Wilson, GA; Rakyan, VK; Teschendorff, AE; Akan, P; Stupka, E; Down, TA; Prokopenko, I; Morison, IM; Mill, J; Pidsley, R; Deloukas, P; Frayling, TM; Hattersley, AT; McCarthy, MI; Beck, S; Hitman, GA; Int Type 2 Diabet 1q Consortium; - view fewer (2010) Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus. PLOS ONE , 5 (11) , Article e14040. 10.1371/journal.pone.0014040.

Bell, CG; Teschendorff, AE; Rakyan, VK; Maxwell, AP; Beck, S; Savage, DA; (2010) Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus. BMC Medical Genomics , 3 , Article 33. 10.1186/1755-8794-3-33.

Li, YR; Zhu, JD; Tian, G; Li, N; Li, QB; Ye, MZ; Zheng, HC; ... Zhang, XQ; + view all Li, YR; Zhu, JD; Tian, G; Li, N; Li, QB; Ye, MZ; Zheng, HC; Yu, JA; Wu, HL; Sun, JH; Zhang, HY; Chen, QA; Luo, RB; Chen, MF; He, YH; Jin, X; Zhang, QH; Yu, C; Zhou, GY; Sun, JF; Huang, YB; Zheng, HS; Cao, HZ; Zhou, XY; Guo, SC; Hu, XD; Li, X; Kristiansen, K; Bolund, L; Xu, JJ; Wang, W; Yang, HM; Wang, JA; Li, RQ; Beck, S; Wang, J; Zhang, XQ; - view fewer (2010) The DNA Methylome of Human Peripheral Blood Mononuclear Cells. PLoS Biology , 8 (11) , Article e1000533. 10.1371/journal.pbio.1000533.

Novakovic, B.; Wong, N. C.; Sibson, M.; Ng, H.-K.; Morley, R.; Manuelpillai, U.; Down, T.; ... Saffery, R.; + view all Novakovic, B.; Wong, N. C.; Sibson, M.; Ng, H.-K.; Morley, R.; Manuelpillai, U.; Down, T.; Rakyan, V. K.; Beck, S.; Hiendleder, S.; Roberts, C. T.; Craig, J. M.; Saffery, R.; - view fewer (2010) DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placenta. Journal of Biological Chemistry , 285 (13) pp. 9583-9593. 10.1074/jbc.M109.064956.

2009

Averdam, A; Petersen, B; Rosner, C; Neff, J; Roos, C; Eberle, M; Aujard, F; ... Walter, L; + view all Averdam, A; Petersen, B; Rosner, C; Neff, J; Roos, C; Eberle, M; Aujard, F; Munich, C; Schempp, W; Carrington, M; Shiina, T; Inoko, H; Knaust, F; Coggill, P; Sehra, H; Beck, S; Abi-Rached, L; Reinhardt, R; Walter, L; - view fewer (2009) A Novel System of Polymorphic and Diverse NK Cell Receptors in Primates. PLOS GENET , 5 (10) , Article e1000688. 10.1371/journal.pgen.1000688.

Dennis, MY; Paracchini, S; Scerri, TS; Prokunina-Olsson, L; Knight, JC; Wade-Martins, R; Coggill, P; ... Monaco, AP; + view all Dennis, MY; Paracchini, S; Scerri, TS; Prokunina-Olsson, L; Knight, JC; Wade-Martins, R; Coggill, P; Beck, S; Green, ED; Monaco, AP; - view fewer (2009) A Common Variant Associated with Dyslexia Reduces Expression of the KIAA0319 Gene. PLOS GENET , 5 (3) , Article e1000436. 10.1371/journal.pgen.1000436.

Novakovic, B; Sibson, M; Ng, HK; Manuelpillai, U; Rakyan, V; Down, T; Beck, S; ... Saffery, R; + view all Novakovic, B; Sibson, M; Ng, HK; Manuelpillai, U; Rakyan, V; Down, T; Beck, S; Fournier, T; Evain-Brion, D; Dimitriadis, E; Craig, JM; Morley, R; Saffery, R; - view fewer (2009) Placenta-specific methylation of the vitamin d 24-hydroxylase gene implications for feedback autoregulation of active vitamin d levels at the fetomaternal interface. The journal of biological chemistry , 284 (22) 14838 - 14848. 10.1074/jbc.M809542200.

Novakovic, B.; Sibson, M.; Ng, H.K.; Manuelpillai, U.; Rakyan, V.; Down, T.; Beck, S.; ... Saffery, R.; + view all Novakovic, B.; Sibson, M.; Ng, H.K.; Manuelpillai, U.; Rakyan, V.; Down, T.; Beck, S.; Fournier, T.; Evain-Brion, D.; Dimitriadis, E.; Craig, J.M.; Morley, R.; Saffery, R.; - view fewer (2009) Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface. Journal of Biological Chemistry , 284 (22) pp. 14838-14848. 10.1074/jbc.M809542200.

Siddle, H.V.; Deakin, J.E.; Coggill, P.; Hart, E.; Cheng, Y.; Wong, E.S.W.; Harrow, J.; ... Belov, K.; + view all Siddle, H.V.; Deakin, J.E.; Coggill, P.; Hart, E.; Cheng, Y.; Wong, E.S.W.; Harrow, J.; Beck, S.; Belov, K.; - view fewer (2009) MHC-linked and un-linked class I genes in the wallaby. BMC Genomics , 10 (1) , Article 310. 10.1186/1471-2164-10-310.

Teschendorff, AE; Menon, U; Gentry-Maharaj, A; Ramus, SJ; Gayther, SA; Apostolidou, S; Jones, A; ... Widschwendter, M; + view all Teschendorff, AE; Menon, U; Gentry-Maharaj, A; Ramus, SJ; Gayther, SA; Apostolidou, S; Jones, A; Lechner, M; Beck, S; Jacobs, IJ; Widschwendter, M; - view fewer (2009) An Epigenetic Signature in Peripheral Blood Predicts Active Ovarian Cancer. PLOS ONE , 4 (12) , Article e8274. 10.1371/journal.pone.0008274.

2008

Sandro Carvalho Santos, P.; Füst, G.; Prohászka, Z.; Volz, A.; Horton, R.; Miretti, M.; Yu, C.-Y.; ... Ziegler, A.; + view all Sandro Carvalho Santos, P.; Füst, G.; Prohászka, Z.; Volz, A.; Horton, R.; Miretti, M.; Yu, C.-Y.; Beck, S.; Uchanska-Ziegler, B.; Ziegler, A.; - view fewer (2008) Association of smoking behavior with an odorant receptor allele telomeric to the human major histocompatibility complex. Genetic Testing , 12 (4) pp. 481-486. 10.1089/gte.2008.0029.

Tomazou, EM; Rakyan, VK; Lefebvre, G; Andrews, R; Ellis, P; Jackson, DK; Langford, C; ... Beck, S; + view all Tomazou, EM; Rakyan, VK; Lefebvre, G; Andrews, R; Ellis, P; Jackson, DK; Langford, C; Francis, MD; Backdahl, L; Miretti, M; Coggill, P; Ottaviani, D; Sheer, D; Murrell, A; Beck, S; - view fewer (2008) Generation of a genomic tiling array of the human Major Histocompatibility Complex (MHC) and its application for DNA methylation analysis. BMC Medical Genomics , 1 , Article 19. 10.1186/1755-8794-1-19.

2006

Laun, K; Coggill, P; Palmer, S; Sims, S; Ning, ZM; Ragoussis, J; Volpi, E; ... Volz, A; + view all Laun, K; Coggill, P; Palmer, S; Sims, S; Ning, ZM; Ragoussis, J; Volpi, E; Wilson, N; Beck, S; Ziegler, A; Volz, A; - view fewer (2006) The leukocyte receptor complex in chicken is characterized by massive expansion and diversification of immunoglobulin-like loci. PLoS Genetics , 2 (5) , Article e73. 10.1371/journal.pgen.0020073.

Lehmann, DJ; Barnardo, MCNM; Fuggle, S; Quiroga, I; Sutherland, A; Warden, DR; Barnetson, L; ... Smith, AD; + view all Lehmann, DJ; Barnardo, MCNM; Fuggle, S; Quiroga, I; Sutherland, A; Warden, DR; Barnetson, L; Horton, R; Beck, S; Smith, AD; - view fewer (2006) Replication of the association of HLA-B7 with Alzheimer's disease: a role for homozygosity? J NEUROINFLAMM , 3 , Article 33. 10.1186/1742-2094-3-33.

Sambrook, JG; Bashirova, A; Andersen, H; Piatak, M; Vernikos, GS; Coggill, P; Lifson, JD; ... Beck, S; + view all Sambrook, JG; Bashirova, A; Andersen, H; Piatak, M; Vernikos, GS; Coggill, P; Lifson, JD; Carrington, M; Beck, S; - view fewer (2006) Identification of the ancestral killer immunoglobulin-like receptor gene in primates. BMC GENOMICS , 7 , Article 209. 10.1186/1471-2164-7-209.

Traherne, JA; Horton, R; Roberts, AN; Miretti, M; Hurles, ME; Stewart, CA; Ashurst, JL; ... Beck, S; + view all Traherne, JA; Horton, R; Roberts, AN; Miretti, M; Hurles, ME; Stewart, CA; Ashurst, JL; Atrazhev, AM; Coggill, P; Palmer, S; Almeida, J; Sims, S; Wilming, LG; Rogers, J; de Jong, PJ; Carrington, M; Elliott, JF; Sawcer, S; Todd, JA; Trowsdale, J; Beck, S; - view fewer (2006) Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history. PLOS GENET , 2 (1) , Article e9. 10.1371/journal.pgen.0020009.

2005

Sambrook, JG; Figueroa, F; Beck, S; (2005) A genome-wide survey of Major Histocompatibility Complex (MHC) genes and their paralogues in zebrafish. BMC GENOMICS , 6 , Article 152. 10.1186/1471-2164-6-152.

2004

Rakyan, VK; Hildmann, T; Novik, KL; Lewin, J; Tost, J; Cox, AV; Andrews, TD; ... Beck, S; + view all Rakyan, VK; Hildmann, T; Novik, KL; Lewin, J; Tost, J; Cox, AV; Andrews, TD; Howe, KL; Otto, T; Olek, A; Fischer, J; Gut, IG; Berlin, K; Beck, S; - view fewer (2004) DNA methylation profiling of the human major histocompatibility complex: A pilot study for the Human Epigenome Project. PLOS BIOL , 2 (12) , Article e405. 10.1371/journal.pbio.0020405.

2002

Liu, Y; Dodds, P; Emilion, G; Mungall, AJ; Dunham, I; Beck, S; Wells, RS; ... Ganesan, TS; + view all Liu, Y; Dodds, P; Emilion, G; Mungall, AJ; Dunham, I; Beck, S; Wells, RS; Charnock, FML; Ganesan, TS; - view fewer (2002) The human homologue of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer. BMC Genetics , 3 , Article 20. 10.1186/1471-2156-3-20.

1992

HAYNES, SR; DOLLARD, C; WINSTON, F; BECK, S; TROWSDALE, J; DAWID, IB; (1992) The bromodomain - a conserved sequence found in human, drosophila and yeast proteins. Nucleic Acids Research , 20 (10) 2603 - 2603. 10.1093/nar/20.10.2603.

This list was generated on Tue Jan 27 13:39:58 2026 GMT.