Browse by UCL people
Group by: Type | Date
Number of items: 87.
2025
Brown, Jeremy Stuart;
Armstrong-James, Darius;
Ayling-Smith, Jonathan;
Backx, Matthijs;
Coleman, Meg;
Connell, David;
Dennison, Paddy;
... Baxter, Caroline; + view all
(2025)
British Thoracic Society Clinical Statement on Aspergillus-related chronic lung disease.
Thorax
, 80
(Suppl 1)
pp. 3-21.
10.1136/thorax-2024-222567.
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2024
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Brown, Jeremy S;
(2024)
The importance of airway IL-1β in patients with bronchiectasis.
European Respiratory Journal
, 64
(2)
, Article 2400997. 10.1183/13993003.00997-2024.
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Brown, Jeremy Stuart;
(2024)
Streptococcus pneumoniae pneumonia: the clinical relevance of capsular serotype.
Thorax
10.1136/thorax-2024-222475.
(In press).
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Elneima, O;
McAuley, HJC;
Leavy, OC;
Chalmers, JD;
Horsley, A;
Ho, LP;
Marks, M;
... Evans, RA; + view all
(2024)
Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study.
International Journal of Epidemiology
, 53
(1)
, Article dyad165. 10.1093/ije/dyad165.
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Feehan, KT;
Bridgewater, HE;
Stenkiewicz-Witeska, J;
De Maeyer, RPH;
Ferguson, J;
Mack, M;
Brown, J;
... Gilroy, DW; + view all
(2024)
Post-resolution macrophages shape long-term tissue immunity and integrity in a mouse model of pneumococcal pneumonia.
Nature Communications
, 15
(1)
, Article 4326. 10.1038/s41467-024-48138-y.
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Polverino, Eva;
De Soyza, Anthony;
Dimakou, Katerina;
Traversi, Letizia;
Bossios, Apostolos;
Crichton, Megan L;
Ringshausen, Felix C;
... Chalmers, James D; + view all
(2024)
The Association Between Bronchiectasis and Chronic Obstructive Pulmonary Disease: Data from the European Bronchiectasis Registry (EMBARC).
American Journal of Respiratory and Critical Care Medicine
, 210
(1)
pp. 119-127.
10.1164/rccm.202309-1614OC.
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2023
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Brown, Jeremy S;
Hurst, John R;
(2023)
Bronchiectasis in low- and middle-income countries: the importance of the wider view.
European Respiratory Journal
, 61
(1)
, Article 2201977. 10.1183/13993003.01977-2022.
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Gil, Eliza;
Wall, Emma;
Noursadeghi, Mahdad;
Brown, Jeremy S;
(2023)
Streptococcus pneumoniae meningitis and the CNS barriers.
Frontiers in Cellular and Infection Microbiology
, 12
, Article 1106596. 10.3389/fcimb.2022.1106596.
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Hill, Helen;
Mitsi, Elena;
Nikolaou, Elissavet;
Blizard, Annie;
Pojar, Sherin;
Howard, Ashleigh;
Hyder-Wright, Angela;
... Ferreira, Daniela M; + view all
(2023)
A Randomised Controlled Trial of Nasal Immunisation with Live Virulence Attenuated Streptococcus pneumoniae Strains Using Human Infection Challenge.
American Journal of Respiratory and Critical Care Medicine
, 208
(8)
pp. 868-878.
10.1164/rccm.202302-0222OC.
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Obolski, Uri;
Swarthout, Todd D;
Kalizang’oma, Akuzike;
Mwalukomo, Thandie S;
Chan, Jia Mun;
Weight, Caroline M;
Brown, Comfort;
... Heyderman, Robert S; + view all
(2023)
The metabolic, virulence and antimicrobial resistance profiles of colonising Streptococcus pneumoniae shift after PCV13 introduction in urban Malawi.
Nature Communications
, 14
(1)
, Article 7477. 10.1038/s41467-023-43160-y.
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Pates, Katharine M;
Periselneris, Jimstan N;
Brown, Jeremy S;
(2023)
Opportunistic bacterial, viral and fungal infections of the lung.
Medicine
, 51
(11)
pp. 777-783.
10.1016/j.mpmed.2023.08.002.
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Pates, Katharine M;
Periselneris, Jimstan N;
Brown, Jeremy S;
(2023)
Pneumonia.
Medicine
, 51
(11)
pp. 763-767.
10.1016/j.mpmed.2023.08.003.
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Zheng, B;
Vivaldi, G;
Daines, L;
Leavy, OC;
Richardson, M;
Elneima, O;
McAuley, HJC;
... Barrett, F; + view all
(2023)
Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls.
The Lancet Regional Health - Europe
, Article 100635. 10.1016/j.lanepe.2023.100635.
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2022
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David, Shannon C;
Brazel, Erin B;
Singleton, Eve;
Minhas, Vikrant;
Laan, Zoe;
Scougall, Catherine;
Chen, Austen Y;
... Alsharifi, Mohammed; + view all
(2022)
A Nonadjuvanted Whole-Inactivated Pneumococcal Vaccine Induces Multiserotype Opsonophagocytic Responses Mediated by Noncapsule-Specific Antibodies.
mBio
10.1128/mbio.02367-22.
(In press).
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Gil, Eliza;
Noursadeghi, Mahdad;
Brown, Jeremy S;
(2022)
Streptococcus pneumoniae interactions with the complement system.
Frontiers in Cellular and Infection Microbiology
, 12
, Article 929483. 10.3389/fcimb.2022.929483.
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Nithichanon, Arnone;
Kewcharoenwong, Chidchamai;
Da-Oh, Hudadini;
Surajinda, Sirithorn;
Khongmee, Aranya;
Koosakunwat, Surathinee;
Wren, Brendan W;
... Lertmemongkolchai, Ganjana; + view all
(2022)
Acinetobacter nosocomialis Causes as Severe Disease as Acinetobacter baumannii in Northeast Thailand: Underestimated Role of A. nosocomialis in Infection.
Microbiology Spectrum
, Article e0283622. 10.1128/spectrum.02836-22.
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Szylar, Gabriella;
Wysoczanski, Riccardo;
Marshall, Helina;
Marks, Daniel JB;
José, Ricardo;
Ehrenstein, Michael E;
Brown, Jeremy S;
(2022)
A novel Streptococcus pneumoniae human challenge model demonstrates Treg lymphocyte recruitment to the infection site.
Scientific Reports
, 12
(1)
, Article 3990. 10.1038/s41598-022-07914-w.
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2021
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Betts, M;
Jarvis, S;
Jeffries, A;
Gori, A;
Chaguza, C;
Msefula, J;
Weight, CM;
... Heyderman, RS; + view all
(2021)
Complete Genome Sequence of Streptococcus pneumoniae Strain BVJ1JL, a Serotype 1 Carriage Isolate from Malawi.
Microbiology Resource Announcements
, 10
(39)
, Article e0071521. 10.1128/MRA.00715-21.
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Brown, JS;
(2021)
Single-Nucleotide Polymorphisms within the cps Loci: Another Potential Source of Clinically Important Genetic Variation for Streptococcus pneumoniae?
Infection and Immunity
, 89
(11)
, Article e00374-21. 10.1128/IAI.00374-21.
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Chong, DLW;
Rebeyrol, C;
José, RJ;
Williams, AE;
Brown, JS;
Scotton, CJ;
Porter, JC;
(2021)
ICAM-1 and ICAM-2 Are Differentially Expressed and Up-Regulated on Inflamed Pulmonary Epithelium, but Neither ICAM-2 nor LFA-1: ICAM-1 Are Required for Neutrophil Migration Into the Airways In Vivo.
Frontiers in Immunology
, 12
, Article 691957. 10.3389/fimmu.2021.691957.
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Ercoli, G;
Ramos‐Sevillano, E;
Pearce, E;
Ragab, S;
Goldblatt, D;
Weckbecker, G;
Brown, JS;
(2021)
Maintained partial protection against Streptococcus pneumoniae despite B‐cell depletion in mice vaccinated with a pneumococcal glycoconjugate vaccine.
Clinical & Translational Immunology
, 11
(1)
10.1002/cti2.1366.
(In press).
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Ercoli, G;
Ramos-Sevillano, E;
Nakajima, R;
De Assis, RR;
Jasinskas, A;
Goldblatt, D;
Felgner, P;
... Brown, J; + view all
(2021)
The Influence of B Cell Depletion Therapy on Naturally Acquired Immunity to Streptococcus pneumoniae.
Frontiers in Immunology
, 11
, Article 611661. 10.3389/fimmu.2020.611661.
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Evans, RA;
McAuley, H;
Harrison, EM;
Shikotra, A;
Singapuri, A;
Sereno, M;
Elneima, O;
... PHOSP-COVID Collaborative Group, .; + view all
(2021)
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.
Lancet Respiratory Medicine
10.1016/S2213-2600(21)00383-0.
(In press).
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Goldblatt, D;
Fiore-Gartland, A;
Johnson, M;
Hunt, A;
Bengt, C;
Zavadska, D;
Snipe, HD;
... Ambrosino, D; + view all
(2021)
Towards a population-based threshold of protection for COVID-19 vaccines.
Vaccine
10.1016/j.vaccine.2021.12.006.
(In press).
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Heightman, M;
Prashar, J;
Hillman, TE;
Marks, M;
Livingston, R;
Ridsdale, HA;
Bell, R;
... Banerjee, A; + view all
(2021)
Post-COVID-19 assessment in a specialist clinical service: a 12-month, single-centre, prospective study in 1325 individuals.
BMJ Open Respiratory Research
, 8
(1)
, Article e001041. 10.1136/bmjresp-2021-001041.
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Kamuyu, G;
Cheng, YS;
Willcocks, S;
Kewcharoenwong, C;
Kiratisin, P;
Taylor, P;
Wren, BW;
... Brown, J; + view all
(2021)
Sequential Vaccination With Heterologous Acinetobacter baumannii Strains Induces Broadly Reactive Antibody Responses.
Frontiers in Immunology
, 12
, Article 705533. 10.3389/fimmu.2021.705533.
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Marshall, H;
Jose, RJ;
Kilian, M;
Petersen, FC;
Brown, JS;
(2021)
Effects of Expression of Streptococcus pneumoniae PspC on the Ability of Streptococcus mitis to Evade Complement-Mediated Immunity.
Frontiers in Microbiology
, 12
, Article 773877. 10.3389/fmicb.2021.773877.
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Ramos-Sevillano, E;
Ercoli, G;
Felgner, P;
Ramiro de Assis, R;
Nakajima, R;
Goldblatt, D;
Heyderman, RS;
... Brown, JS; + view all
(2021)
Preclinical Development of Virulence Attenuated Streptococcus pneumoniae Strains Able to Enhance Protective Immunity Against Pneumococcal Infection.
American Journal of Respiratory and Critical Care Medicine
, 203
(8)
pp. 1037-1040.
10.1164/rccm.202011-4161LE.
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Ramos-Sevillano, E;
Ercoli, G;
Guerra-Assunção, JA;
Felgner, P;
Ramiro de Assis, R;
Nakajima, R;
Goldblatt, D;
... Brown, JS; + view all
(2021)
Protective Effect of Nasal Colonisation with ∆cps/piaA and ∆cps/proABCStreptococcus pneumoniae Strains against Recolonisation and Invasive Infection.
Vaccines
, 9
(3)
, Article 261. 10.3390/vaccines9030261.
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Weight, CM;
Jochems, SP;
Adler, H;
Ferreira, DM;
Brown, JS;
Heyderman, RS;
(2021)
Insights Into the Effects of Mucosal Epithelial and Innate Immune Dysfunction in Older People on Host Interactions With Streptococcus pneumoniae.
Frontiers in Cellular and Infection Microbiology
, 11
, Article ARTN 651. 10.3389/fcimb.2021.651474.
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2020
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Avari, M;
Brown, JS;
(2020)
Management of community-acquired pneumonia: essential tips for the physician on call.
British Journal of Hospital Medicine
, 81
(5)
10.12968/hmed.2020.0124.
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Durmort, C;
Ercoli, G;
Ramos-Sevillano, E;
Chimalapati, S;
Haigh, RD;
De Ste Croix, M;
Gould, K;
... Brown, JS; + view all
(2020)
Deletion of the Zinc Transporter Lipoprotein AdcAII Causes Hyperencapsulation of Streptococcus pneumoniae Associated with Distinct Alleles of the Type I Restriction-Modification System.
mBio
, 11
(2)
, Article e00445-20. 10.1128/mBio.00445-20.
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José, RJ;
Periselneris, JN;
Brown, JS;
(2020)
Opportunistic bacterial, viral and fungal infections of the lung.
Medicine
, 48
(6)
pp. 366-372.
10.1016/j.mpmed.2020.03.006.
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José, RJ;
Williams, A;
Manuel, A;
Brown, JS;
Chambers, RC;
(2020)
Targeting coagulation activation in severe COVID-19 pneumonia: lessons from bacterial pneumonia and sepsis.
European Respiratory Review
, 29
(157)
, Article 200240. 10.1183/16000617.0240-2020.
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Lipman, M;
Chambers, RC;
Singer, M;
Brown, JS;
(2020)
SARS-CoV-2 pandemic: clinical picture of COVID-19 and implications for research.
Thorax
10.1136/thoraxjnl-2020-215024.
(In press).
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Mandal, S;
Barnett, J;
Brill, SE;
Brown, JS;
Denneny, EK;
Hare, SS;
Heightman, M;
... ARC Study Group, .; + view all
(2020)
'Long-COVID': a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19.
Thorax
10.1136/thoraxjnl-2020-215818.
(In press).
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Marshall, H;
Aguayo, S;
Kilian, M;
Petersen, F;
Bozec, L;
Brown, J;
(2020)
In Vivo Relationship between the Nano-Biomechanical Properties of Streptococcal Polysaccharide Capsules and Virulence Phenotype.
ACS Nano
, 14
(1)
pp. 1070-1083.
10.1021/acsnano.9b08631.
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Orihuela, CJ;
Maus, UA;
Brown, JS;
(2020)
Can animal models really teach us anything about pneumonia? Pro.
European Respiratory Journal
, 55
(1)
, Article 1901539. 10.1183/13993003.01539-2019.
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Periselneris, JN;
Brown, JS;
José, RJ;
(2020)
Pneumonia.
Medicine
, 48
(6)
pp. 351-355.
10.1016/j.mpmed.2020.03.002.
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Terra, VS;
Plumptre, CD;
Wall, EC;
Brown, JS;
Wren, BW;
(2020)
Constructing Mutants in Serotype 1 Streptococcus pneumoniae strain 519/43.
Journal of Visualized Experiments
(163)
, Article e61594. 10.3791/61594.
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Terra, VS;
Plumptre, CD;
Wall, EC;
Brown, JS;
Wren, BW;
(2020)
Construction of a pneumolysin deficient mutant in streptococcus pneumoniae serotype 1 strain 519/43 and phenotypic characterisation.
Microbial Pathogenesis
, 141
, Article 103999. 10.1016/j.micpath.2020.103999.
(In press).
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Wall, EC;
Brownridge, P;
Laing, G;
Terra, VS;
Mlozowa, V;
Denis, B;
Nyirenda, M;
... Brown, JS; + view all
(2020)
CSF Levels of Elongation Factor Tu Is Associated With Increased Mortality in Malawian Adults With Streptococcus pneumoniae Meningitis.
Frontiers in Cellular and Infection Microbiology
, 10
, Article 603623. 10.3389/fcimb.2020.603623.
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2019
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Aldabayan, YS;
Ridsdale, HA;
Alrajeh, AM;
Aldhahir, AM;
Lemson, A;
Alqahtani, JS;
Brown, JS;
(2019)
Pulmonary rehabilitation, physical activity and aortic stiffness in COPD.
Respiratory Research
, 20
(1)
, Article 166. 10.1186/s12931-019-1135-6.
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Brown, JS;
(2019)
Improving Pulmonary Immunity to Bacterial Pathogens Through Streptococcus pneumoniae Colonisation of the Nasopharynx.
American Journal of Respiratory and Critical Care Medicine
10.1164/rccm.201910-2047ED.
(In press).
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José, RJ;
Hall, J;
Brown, JS;
(2019)
De novo bronchiectasis in haematological malignancies: patient characteristics, risk factors and survival.
ERJ Open Research
, 5
(4)
, Article 00166-2019. 10.1183/23120541.00166-2019.
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Nasir, T;
Lee, C;
Lawrence, AS;
Brown, JS;
(2019)
Invasive aspergillosis complicating treatment with tyrosine kinase inhibitors.
BMJ Case Reports
, 12
(1)
10.1136/bcr-2018-226121.
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Periselneris, J;
Brown, JS;
(2019)
A clinical approach to respiratory disease in patients with hematological malignancy, with a focus on respiratory infection.
Medical Mycology
, 57
(3)
S318-S327.
10.1093/mmy/myy138.
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Periselneris, J;
Ercoli, G;
Pollard, T;
Chimalapati, S;
Camberlein, E;
Szylar, G;
Hyams, C;
... Brown, JS; + view all
(2019)
Relative Contributions of Extracellular and Internalized Bacteria to Early Macrophage Proinflammatory Responses to Streptococcus pneumoniae.
MBio
, 10
(5)
, Article e02144-19. 10.1128/mBio.02144-19.
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Quan, K;
Tanno, R;
Shipley, RJ;
Brown, JS;
Jacob, J;
Hurst, JR;
Hawkes, DJ;
(2019)
Reproducibility of an airway tapering measurement in computed tomography with application to bronchiectasis.
Journal of Medical Imaging
, 6
(3)
, Article 034003. 10.1117/1.JMI.6.3.034003.
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Ramos-Sevillano, E;
Ercoli, G;
Brown, JS;
(2019)
Mechanisms of Naturally Acquired Immunity to Streptococcus pneumoniae.
[Review].
Frontiers in Immunology
, 10
, Article 358. 10.3389/fimmu.2019.00358.
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Rezaei Javan, R;
Ramos-Sevillano, E;
Akter, A;
Brown, J;
Brueggemann, AB;
(2019)
Prophages and satellite prophages are widespread in Streptococcus and may play a role in pneumococcal pathogenesis.
Nature Communications
, 10
(1)
, Article 4852. 10.1038/s41467-019-12825-y.
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Weight, CM;
Venturini, C;
Pojar, S;
Jochems, SP;
Reiné, J;
Nikolaou, E;
Solórzano, C;
... Heyderman, RS; + view all
(2019)
Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface.
Nature Communications
, 10
(1)
, Article 3060. 10.1038/s41467-019-11005-2.
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2018
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Chan, W-Y;
Entwisle, C;
Ercoli, G;
Ramos-Sevillano, E;
McIlgorm, A;
Cecchini, P;
Bailey, C;
... Brown, JS; + view all
(2018)
A novel, multiple-antigen pneumococcal vaccine protects against lethal Streptococcus pneumoniae challenge.
Infection and Immunity
10.1128/IAI.00846-18.
(In press).
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Hill, S;
Entwisle, C;
Pang, Y;
Joachim, M;
McIlgorm, A;
Dalton, K;
Burbidge, P;
... Bailey, C; + view all
(2018)
Immunogenicity and mechanisms of action of PnuBioVax, a multi-antigen serotype-independent prophylactic vaccine against infection with Streptococcus pneumoniae.
Vaccine
, 36
(29)
pp. 4255-4264.
10.1016/j.vaccine.2018.05.122.
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Rashwan, R;
Varano Della Vergiliana, JF;
Lansley, SM;
Cheah, HM;
Popowicz, N;
Paton, JC;
Waterer, GW;
... Lee, YCG; + view all
(2018)
Streptococcus pneumoniae potently induces cell death in mesothelial cells.
PLoS One
, 13
(7)
, Article e0201530. 10.1371/journal.pone.0201530.
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Reglinski, M;
Ercoli, G;
Plumptre, C;
Kay, E;
Petersen, FC;
Paton, JC;
Wren, BW;
(2018)
A recombinant conjugated pneumococcal vaccine that protects against murine infections with a similar efficacy to Prevnar-13.
NPJ Vaccines
, 3
, Article 53. 10.1038/s41541-018-0090-4.
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2017
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Aguayo, S;
Marshall, H;
Pratten, J;
Bradshaw, D;
Brown, JS;
Porter, SR;
Spratt, D;
(2017)
Early Adhesion of Candida albicans onto Dental Acrylic Surfaces.
Journal of Dental Research
, 96
(8)
pp. 917-923.
10.1177/0022034517706354.
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Cuadrado, MM;
Ahmed, A;
Carpenter, B;
Brown, JS;
(2017)
Cytomegalovirus pneumonitis complicated by a central peribronchial pattern of organising pneumonia.
Respiratory Medicine Case Reports
, 20
pp. 184-187.
10.1016/j.rmcr.2017.02.005.
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José, RJ;
Brown, JS;
(2017)
Adult pneumococcal vaccination: advances, impact, and unmet needs.
Current Opinion in Pulmonary Medicine
, 23
(3)
pp. 225-230.
10.1097/MCP.0000000000000369.
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Junges, R;
Salvadori, G;
Shekhar, S;
Åmdal, HA;
Periselneris, JN;
Chen, T;
Brown, JS;
(2017)
A quorum-sensing system that regulates Streptococcus pneumoniae biofilm formation and surface polysaccharide production.
mSphere
, 2
(5)
, Article e00324-17. 10.1128/mSphere.00324-17.
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Popowicz, ND;
Lansley, SM;
Cheah, HM;
Kay, ID;
Carson, CF;
Waterer, GW;
Paton, JC;
... Lee, YCG; + view all
(2017)
Human pleural fluid is a potent growth medium for Streptococcus pneumoniae.
PLoS One
, 12
(11)
, Article e0188833. 10.1371/journal.pone.0188833.
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Saleh, AD;
Chalmers, JD;
De Soyza, A;
Fardon, TC;
Koustas, SO;
Scott, J;
Simpson, AJ;
... Hurst, JR; + view all
(2017)
The heterogeneity of systemic inflammation in bronchiectasis.
Respiratory Medicine
, 127
pp. 33-39.
10.1016/j.rmed.2017.04.009.
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Saleh, AD;
Kwok, B;
Brown, JS;
Hurst, JR;
(2017)
Correlates and assessment of excess cardiovascular risk in bronchiectasis.
European Respiratory Journal
, 50
(5)
, Article 1701127. 10.1183/13993003.01127-2017.
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Wilson, R;
Cohen, JM;
Reglinski, M;
Jose, RJ;
Chan, WY;
Marshall, H;
de Vogel, C;
... Brown, JS; + view all
(2017)
Naturally Acquired Human Immunity to Pneumococcus Is Dependent on Antibody to Protein Antigens.
PLoS Pathogens
, 13
(1)
, Article e1006137. 10.1371/journal.ppat.1006137.
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2016
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José, RJ;
Brown, JS;
(2016)
Predicting bacteraemia or rapid identification of the causative pathogen in community acquired pneumonia: where should the priority lie?
Eur Respir J
, 48
(3)
pp. 619-622.
10.1183/13993003.00941-2016.
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José, RJ;
Brown, JS;
(2016)
Opportunistic bacterial, viral and fungal infections of the lung.
Medicine
, 44
(6)
pp. 378-383.
10.1016/j.mpmed.2016.03.015.
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Kohler, S;
Voß, F;
Gómez Mejia, A;
Brown, JS;
Hammerschmidt, S;
(2016)
Pneumococcal lipoproteins involved in bacterial fitness, virulence, and immune evasion.
FEBS Letters
, 590
(21)
pp. 3820-3839.
10.1002/1873-3468.12352.
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Navaratnam, V;
Millett, ER;
Hurst, JR;
Thomas, SL;
Smeeth, L;
Hubbard, RB;
Brown, J;
(2016)
Bronchiectasis and the risk of cardiovascular disease: a population-based study.
Thorax
10.1136/thoraxjnl-2015-208188.
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