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Article

Abdi, Suad S; De Haan, Michelle; Kirkham, Fenella J; (2023) Neuroimaging and Cognitive Function in Sickle Cell Disease: A Systematic Review. Children , 10 (3) , Article 532. 10.3390/children10030532. Green open access
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Abdullahi, Shehu U; Jibir, Binta W; Bello-Manga, Halima; Gambo, Safiya; Inuwa, Hauwa; Tijjani, Aliyu G; Idris, Nura; ... DeBaun, Michael R; + view all (2022) Hydroxyurea for primary stroke prevention in children with sickle cell anaemia in Nigeria (SPRING): a double-blind, multicentre, randomised, phase 3 trial. The Lancet Haematology , 9 (1) E26-E37. 10.1016/S2352-3026(21)00368-9. Green open access
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Abdullahi, SU; Wudil, BJ; Bello-Manga, H; Musa, AB; Gambo, S; Galadanci, NA; Aminu, H; ... DeBaun, MR; + view all (2021) Primary prevention of stroke in children with sickle cell anemia in sub-Saharan Africa: rationale and design of phase III randomized clinical trial. Pediatric Hematology and Oncology , 38 (1) pp. 49-64. 10.1080/08880018.2020.1810183. Green open access
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Ampomah, Mary A; Drake, Jermon A; Anum, Adote; Amponsah, Benjamin; Dei-Adomakoh, Yvonne; Anie, Kofi; Mate-Kole, Christopher C; ... Kirkham, Fenella J; + view all (2022) A case-control and seven-year longitudinal neurocognitive study of adults with sickle cell disease in Ghana. British Journal of Haematology 10.1111/bjh.18386. (In press). Green open access
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Arigliani, Michele; Kirkham, Fenella J; Sahota, Sati; Riley, Mollie; Liguoro, Ilaria; Castriotta, Luigi; Gupta, Atul; ... Aurora, Paul; + view all (2022) Lung Clearance Index May Detect Early Peripheral Lung Disease in Sickle Cell Anemia. Annals of the American Thoracic Society , 19 (9) pp. 1507-1515. 10.1513/AnnalsATS.202102-168OC. Green open access
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Beslow, LA; Linds, AB; Fox, CK; Kossorotoff, M; Zuñiga Zambrano, YC; Hernández-Chávez, M; Hassanein, SMA; ... International Pediatric Stroke Study Group; + view all (2021) Pediatric Ischemic Stroke: An Infrequent Complication of SARS-CoV-2. Annals of Neurology , 89 (4) pp. 657-665. 10.1002/ana.25991. Green open access
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Beslow, LA; Dowling, MM; Hassanein, SMA; Lynch, JK; Zafeiriou, D; Sun, LR; Kopyta, I; ... Lee, J; + view all (2018) Mortality After Pediatric Arterial Ischemic Stroke. Pediatrics , 141 (5) , Article e20174146. 10.1542/peds.2017-4146. Green open access
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Braun, K.P.J.; Bulder, M.M.M.; Chabrier, S.; Kirkham, F.J.; Uiterwaal, C.S.P.; Tardieu, M.; Sébire, G.; (2009) The course and outcome of unilateral intracranial arteriopathy in 79 children with ischaemic stroke. Brain , 132 (2) pp. 544-557. 10.1093/brain/awn313. Green open access
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Brennan, LC; Kirkham, FJ; Gavlak, JC; (2020) Sleep-disordered breathing and comorbidities: Role of the upper airway and craniofacial skeleton. Nature and Science of Sleep , 12 pp. 907-936. 10.2147/NSS.S146608. Green open access
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Brewin, J; Tewari, S; Menzel, S; Kirkham, F; Inusa, B; Renney, G; Ward, M; (2019) The effects of hydroxycarbamide on the plasma proteome of children with sickle cell anaemia. British Journal of Haematology , 186 (6) pp. 879-886. 10.1111/bjh.15996. Green open access
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Cermakova, P; Pikhart, H; Ruiz, M; Kubinova, R; Bobak, M; (2020) Socioeconomic position in childhood and depressive symptoms in later adulthood in the Czech Republic. Journal of Affective Disorders , 272 pp. 17-23. 10.1016/j.jad.2020.03.099. Green open access
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Choi, EJ; Levin, D; Robertson, A; Kirkham, FJ; Muthusami, P; Krishnan, P; Shroff, M; ... Dlamini, N; + view all (2024) Assessment of MR blood-oxygen-level-dependent (BOLD) cerebrovascular reactivity under general anesthesia in children with moyamoya. Pediatric Radiology , 54 pp. 1325-1336. 10.1007/s00247-024-05930-8. Green open access
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Choi, Eun Jung; Westmacott, Robyn; Kirkham, Fenella J; Robertson, Amanda; Muthusami, Prakash; Shroff, Manohar; Moharir, Mahendranath; ... Dlamini, Nomazulu; + view all (2022) Fronto-Parietal and White Matter Haemodynamics Predict Cognitive Outcome in Children with Moyamoya Independent of Stroke. Translational Stroke Research , 13 pp. 757-773. 10.1007/s12975-022-01003-w. Green open access
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Cohen, RT; Rodeghier, M; Kirkham, FJ; Rosen, CL; Kirkby, J; DeBaun, MR; Strunk, RC; (2016) Exhaled nitric oxide: Not associated with asthma, symptoms, or spirometry in children with sickle cell anemia. Journal of Allergy and Clinical Immunology , 138 (5) 1338-1343.e4. 10.1016/j.jaci.2016.06.043. Green open access
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Cohen, RT; Strunk, RC; Rodeghier, M; Rosen, CL; Kirkham, FJ; Kirkby, J; DeBaun, MR; (2016) Pattern of Lung Function Is Not Associated with Prior or Future Morbidity in Children with Sickle Cell Anemia. Annals of the American Thoracic Society , 13 (8) pp. 1314-1323. 10.1513/AnnalsATS.201510-706OC. Green open access
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Cox, SE; ELLINS, EA; Marealle, AI; Newton, C; Soka, D; Sasi, P; di Tanna, GL; ... Kirkham, F; + view all (2018) Ready-to-use food supplement +/- arginine & citrulline with daily chloroquine in Tanzanian children with sickle cell disease: a double blind random order cross-over trial. The Lancet Haematology , 5 (4) e147-e160. 10.1016/S2352-3026(18)30020-6. Gold open access
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Cox, SE; Hart, E; Kirkham, FJ; Stotesbury, H; (2020) L-Glutamine in sickle cell disease. Drugs of Today , 56 (4) pp. 257-268. 10.1358/dot.2020.56.4.3110575.

Cox, SE; Makani, J; Soka, D; L'Esperence, VS; Kija, E; Dominguez-Salas, P; Newton, CRJ; ... Kirkham, FJ; + view all (2014) Haptoglobin, alpha-thalassaemia and glucose-6-phosphate dehydrogenase polymorphisms and risk of abnormal transcranial Doppler among patients with sickle cell anaemia in Tanzania. British Journal of Haematology , 165 (5) pp. 699-706. 10.1111/bjh.12791. Green open access
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DeBaun, MR; Gordon, M; McKinstry, RC; Noetzel, MJ; White, DA; Sarnaik, SA; Meier, ER; ... Casella, JF; + view all (2014) Controlled Trial of Transfusions for Silent Cerebral Infarcts in Sickle Cell Anemia. New England Journal of Medicine , 371 pp. 699-710. 10.1056/NEJMoa1401731. Green open access
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DeBaun, MR; Jordan, LC; King, AA; Schatz, J; Vichinsky, E; Fox, CK; McKinstry, RC; ... Murad, MH; + view all (2020) American Society of Hematology 2020 guidelines for sickle cell disease: prevention, diagnosis, and treatment of cerebrovascular disease in children and adults. Blood Advances , 4 (8) pp. 1554-1588. 10.1182/bloodadvances.2019001142. Green open access
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DeBaun, MR; Kirkham, FJ; (2016) New option for primary stroke prevention in sickle cell anaemia. The Lancet , 387 (10019) pp. 626-627. 10.1016/S0140-6736(15)01130-7. Green open access
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DeBaun, MR; Kirkham, FJ; (2016) Central nervous system complications and management in sickle cell disease. Blood , 127 (7) pp. 829-838. 10.1182/blood-2015-09-618579. Green open access
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deVeber, G; Kirkham, F; Shannon, K; Brandao, L; Straeter, R; Kenet, G; Clausnizer, H; ... Nowak-Goettl, U; + view all (2019) Recurrent Stroke: The Role Of Thrombophilia In A Large International Pediatric Stroke Population. [Corrigendum]. Haematologica , 104 (10) p. 2116. 10.3324/haematol.2019.234666. Green open access
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deVeber, G; Kirkham, F; Shannon, K; Brandão, L; Sträter, R; Kenet, G; Clausnizer, H; ... Nowak-Göttl, U; + view all (2019) Recurrent stroke: the role of thrombophilia in a large international pediatric stroke population. Haematologica , 104 (8) pp. 1676-1681. 10.3324/haematol.2018.211433. Green open access
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Dlamini, N; Pohl, K; Eley, B; Van Toorn, R; Kilborn, T; Padayachee, S; Pontigon, A-M; ... Wilmshurst, J; + view all (2020) Stroke transcranial Doppler in children with human immunodeficiency virus. Developmental Medicine & Child Neurology , 62 (6) pp. 735-741. 10.1111/dmcn.14439. Green open access
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Dlamini, N; Saunders, DE; Bynevelt, M; Trompeter, S; Cox, TC; Bucks, RS; Kirkham, FJ; (2017) Nocturnal oxyhemoglobin desaturation and arteriopathy in a pediatric sickle cell disease cohort. Neurology , 89 (24) 10.1212/WNL.0000000000004728. Green open access
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Dlamini, N; Shah-Basak, P; Leung, J; Kirkham, F; Shroff, M; Kassner, A; Robertson, A; ... Logan, W; + view all (2018) Breath-Hold Blood Oxygen Level-Dependent MRI: A Tool for the Assessment of Cerebrovascular Reserve in Children with Moyamoya Disease. American Journal of Neuroradiology , 39 (9) pp. 1717-1723. 10.3174/ajnr.A5739. Green open access
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Dlamini, N; Slim, M; Kirkham, F; Shroff, M; Dirks, P; Moharir, M; MacGregor, D; ... Logan, W; + view all (2020) Predicting Ischemic Risk Using Blood Oxygen Level–Dependent MRI in Children with Moyamoya. American Journal of Neuroradiology , 41 (1) pp. 160-166. 10.3174/ajnr.A6324. Green open access
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Doniza, Liad; Lee, Mitchel; Blumenfeld-Katzir, Tamar; Artzi, Moran; Ben-Bashat, Dafna; Aizenstein, Orna; Radunsky, Dvir; ... Ben-Eliezer, Noam; + view all (2025) Noise propagation and MP-PCA image denoising for high-resolution quantitative R₂*, T₂*, and magnetic susceptibility mapping (QSM). IEEE Transactions on Biomedical Engineering 10.1109/TBME.2025.3566561. (In press). Green open access
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Dowling, MM; Kirkham, FJ; (2016) Stroke in sickle cell anaemia is more than stenosis and thrombosis: the role of anaemia and hyperemia in ischaemia. [Editorial comment]. British Journal of Haematology 10.1111/bjh.14422. Green open access
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Dowling, MM; Quinn, CT; Ramaciotti, C; Kanter, J; Osunkwo, I; Inusa, B; Iyer, R; ... PFAST Investigators, .; + view all (2017) Increased prevalence of potential right-to-left shunting in children with sickle cell anaemia and stroke. British Journal of Haematology , 176 (2) pp. 300-308. 10.1111/bjh.14391. Green open access
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Downes, M; Berg, C; Kirkham, FJ; Kischkel, L; McMurray, I; de Haan, M; (2018) Task utility and norms for the Preschool Executive Task Assessment (PETA). Child Neuropsychology , 24 (6) pp. 784-798. 10.1080/09297049.2017.1333092. Green open access
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Downes, M; De Haan, M; Kirkham, FJ; Telfer, PT; (2017) Parent reported sleep problems in preschool children with sickle cell anemia and controls in East London. Pediatric Blood & Cancer , 64 (6) , Article e26337. 10.1002/pbc.26337. Green open access
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Downes, M; de Haan, M; O'Leary, T; Telfer, PT; Kirkham, FJ; (2018) Temperament in preschool children with sickle cell anaemia. Archives of Disease in Childhood 10.1136/archdischild-2018-315054. (In press). Green open access
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Downes, M; de Haan, M; Telfer, PT; Kirkham, FJ; (2019) The Role of Family Functioning in the Development of Executive Functions in Preschool Children with Sickle Cell Anemia. Developmental Neuropsychology , 44 (6) pp. 452-467. 10.1080/87565641.2019.1660779. Green open access
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Downes, M; Kirkham, FJ; Berg, C; Telfer, P; De Haan, M; (2019) Executive performance on the preschool executive task assessment in children with sickle cell anemia and matched controls. Child Neuropsychology , 25 (2) pp. 278-285. 10.1080/09297049.2018.1491962. Green open access
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Downes, M; Kirkham, FJ; Telfer, PT; de Haan, M; (2018) Assessment of Executive Functions in Preschool Children With Sickle Cell Anemia. Journal of the International Neuropsychological Society , 24 (9) , Article Special Issue. 10.1017/S1355617718000255. Green open access
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Downes, M; Kirkham, FJ; Telfer, PT; De Haan, M; (2018) Altered Neurophysiological Processing of Auditory Attention in Preschool Children With Sickle Cell Disease. Journal of Pediatric Psychology , 43 (8) pp. 856-869. 10.1093/jpepsy/jsx115. Green open access
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Farrell, AT; Panepinto, J; Carroll, CP; Darbari, DS; Desai, AA; King, AA; Adams, RJ; ... Zempsky, WT; + view all (2019) End points for sickle cell disease clinical trials: patient-reported outcomes, pain, and the brain. Blood Advances , 3 (23) pp. 3982-4001. 10.1182/bloodadvances.2019000882. Green open access
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Felling, RJ; Rafay, MF; Bernard, TJ; Carpenter, JL; Dlamini, N; Hassanein, SMA; Jordan, LC; ... International Pediatric Stroke Study Group; + view all (2020) Predicting Recovery and Outcome after Pediatric Stroke: Results from the International Pediatric Stroke Study. Annals of Neurology , 87 (6) pp. 840-852. 10.1002/ana.25718. Green open access
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Galadanci, NA; Abdullahi, SU; Abubakar, SA; Wudil, BJ; Aminu, H; Tijjani, A; Abba, MS; ... DeBaun, MR; + view all (2020) Moderate-Dose Hydroxyurea for Primary Prevention of Strokes in Nigerian Children with Sickle Cell Disease: Final Results of the SPIN Trial. American Journal of Hematology , 95 (9) E247-E250. 10.1002/ajh.25900. Green open access
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Galadanci, NA; Abdullahi, SU; Vance, LD; Tabari, AM; Ali, S; Belonwu, R; Salihu, A; ... DeBaun, MR; + view all (2017) Feasibility trial for primary stroke prevention in children with sickle cell anemia in Nigeria (SPIN trial). American Journal of Hematology , 92 (8) pp. 780-788. 10.1002/ajh.24770. Green open access
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Galadanci, NA; Abdullahi, SU; Vance, LD; Tabari, MA; Abubakar, S; Belonwu, R; Salihu, A; ... DeBaun, MR; + view all (2017) Implementing a standard-of-care clinic for stroke prevention in children with sickle cell disease in Nigeria: a feasible strategy outside a clinical trial setting. Blood Advances , 1 pp. 23-25. 10.1182/bloodadvances.2017GS101266. Green open access
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Gavlak, JC; Stocks, J; Laverty, A; Fettes, E; Bucks, R; Sonnappa, S; Cooper, J; ... Kirkham, FJ; + view all (2013) The Young Everest Study: preliminary report of changes in sleep and cerebral blood flow velocity during slow ascent to altitude in unacclimatised children. Archives of Disease in Childhood , 98 (5) 356 -362. 10.1136/archdischild-2012-302512. Green open access
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Ghafuri, DL; Greene, BC; Musa, B; Gambo, A; Sani, A; Abdullahi, S; Wudil, BJ; ... Jordan, LC; + view all (2021) Capacity Building for Primary Stroke Prevention Teams in Children Living With Sickle Cell Anemia in Africa. Pediatric Neurology , 125 pp. 9-15. 10.1016/j.pediatrneurol.2021.08.010. Green open access
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Goeggel Simonetti, B; Rafay, MF; Chung, M; Lo, WD; Beslow, LA; Billinghurst, LL; Fox, CK; ... IPSS Study Group; + view all (2020) Comparative study of posterior and anterior circulation stroke in childhood: Results from the International Pediatric Stroke Study. Neurology , 94 (4) e337-e344. 10.1212/WNL.0000000000008837. Green open access
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Guilliams, KP; Kirkham, FJ; Holzhauer, S; Pavlakis, S; Philbrook, B; Amlie-Lefond, C; Noetzel, MJ; ... Dowling, MM; + view all (2019) Arteriopathy Influences Pediatric Ischemic Stroke Presentation, but Sickle Cell Disease Influences Stroke Management. Stroke , 50 (5) pp. 1089-1094. 10.1161/STROKEAHA.118.022800. Green open access
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Hales, PW; Kawadler, JM; Aylett, SE; Kirkham, FJ; Clark, CA; (2014) Arterial spin labeling characterization of cerebral perfusion during normal maturation from late childhood into adulthood: normal 'reference range' values and their use in clinical studies. Journal of Cerebral Blood Flow and Metabolism , 34 (5) pp. 776-784. 10.1038/jcbfm.2014.17. Green open access
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Hales, PW; Kirkham, FJ; Clark, CA; (2016) A general model to calculate the spin-lattice (T1) relaxation time of blood, accounting for haematocrit, oxygen saturation and magnetic field strength. Journal of Cerebral Blood Flow & Metabolism , 36 (2) pp. 370-374. 10.1177/0271678X15605856. Green open access
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Hamdule, Shifa; Kirkham, Fenella J; (2023) Brain Volumes and Cognition in Patients with Sickle Cell Anaemia: A Systematic Review and Meta-Analysis. Children , 10 (8) , Article 1360. 10.3390/children10081360. Green open access
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Hamdule, Shifa; Kölbel, Melanie; Stotesbury, Hanne; Murdoch, Russell; Clayden, Jonathan D; Sahota, Sati; Hood, Anna Marie; ... Kirkham, Fenella Jane; + view all (2023) Effects of regional brain volumes on cognition in sickle cell anemia: A developmental perspective. Frontiers in Neurology , 14 , Article 1101223. 10.3389/fneur.2023.1101223. Green open access
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Hill, CM; Baya, A; Gavlak, J; Carroll, A; Heathcote, K; Dimitriou, D; L'Esperance, V; ... Hogan, AM; + view all (2016) Adaptation to Life in the High Andes: Nocturnal Oxyhemoglobin Saturation in Early Development. Sleep , 39 (5) pp. 1001-1008. 10.5665/sleep.5740. Green open access
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Hirtz, D; Kirkham, FJ; (2019) Sickle Cell Disease and Stroke. Pediatric Neurology , 95 pp. 34-41. 10.1016/j.pediatrneurol.2019.02.018. Green open access
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Hogan, AM; Telfer, PT; Kirkham, FJ; de Haan, M; (2013) Precursors of executive function in infants with sickle cell anemia. Journal of Child Neurology , 28 (10) 1197 -1202. 10.1177/0883073812453495. Green open access
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Hood, AM; Kölbel, M; Stotesbury, H; Kawadler, J; Slee, A; Inusa, B; Pelidis, M; ... Liossi, C; + view all (2021) Biopsychosocial Predictors of Quality of Life in Paediatric Patients With Sickle Cell Disease. Frontiers in Psychology , 12 , Article 681137. 10.3389/fpsyg.2021.681137. Green open access
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Hood, AM; Stotesbury, H; Kölbel, M; DeHaan, M; Downes, M; Kawadler, JM; Sahota, S; ... Kirkham, FJ; + view all (2021) Study of montelukast in children with sickle cell disease (SMILES): a study protocol for a randomised controlled trial. Trials , 22 , Article 690. 10.1186/s13063-021-05626-6. Green open access
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Hood, AM; Stotesbury, H; Murphy, J; Kölbel, M; Slee, A; Springall, C; Paradis, M; ... Crosby, LE; + view all (2021) Attitudes About COVID-19 and Health (ATTACH): Online Survey and Mixed Methods Study. JMIR Mental Health , 8 (10) , Article e29963. 10.2196/29963. Green open access
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Hood, Anna M; Crosby, Lori E; Stotesbury, Hanne; Kölbel, Melanie; Kirkham, Fenella J; (2022) Considerations for Selecting Cognitive Endpoints and Psychological Patient-Reported Outcomes for Clinical Trials in Pediatric Patients With Sickle Cell Disease. Frontiers in Neurology , 13 , Article 835823. 10.3389/fneur.2022.835823. Green open access
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Howard, J; Inusa, B; Liossi, C; Jacob, E; Murphy, PB; Hart, N; Gavlak, J; ... Cheng, MY; + view all (2015) Prevention of Morbidity in sickle cell disease: qualitative outcomes, pain and quality of life in a randomised cross-over pilot trial of overnight supplementary oxygen and auto-adjusting continuous positive airways pressure (POMS2a): study protocol for a randomised controlled trial. Trials , 16 , Article 376. 10.1186/s13063-015-0883-y. Green open access
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Howard, J; Lee, SA; Inusa, B; Cheng, MYE; Bavenjit, C; Reading, IC; Wakeford, SA; ... Liossi, C; + view all (2019) Prevention of Morbidity in Sickle Cell Disease (POMS2a)-overnight auto-adjusting continuous positive airway pressure compared with nocturnal oxygen therapy: a randomised crossover pilot study examining patient preference and safety in adults and children. Trials , 20 (1) , Article 442. 10.1186/s13063-019-3461-x. Green open access
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Howard, J; Slee, AE; Skene, S; Inusa, B; Kawadler, J; Downes, M; Gavlak, J; ... Liossi, C; + view all (2018) Overnight auto-adjusting continuous airway pressure + standard care compared with standard care alone in the prevention of morbidity in sickle cell disease phase II (POMS2b): study protocol for a randomised controlled trial. Trials , 19 (1) , Article 55. 10.1186/s13063-017-2419-0. Green open access
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Idro, R; Gwer, S; Williams, TN; Otieno, T; Uyoga, S; Fegan, G; Kager, PA; ... Newton, CR; + view all (2010) Iron deficiency and acute seizures: results from children living in rural Kenya and a meta-analysis. PLoS One , 5 (11) , Article e14001. 10.1371/journal.pone.0014001. Green open access
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Jacob, Mboka; Kawadler, Jamie M; Murdoch, Russell; Ahmed, Magda; Tutuba, Hilda; Masamu, Upendo; Shmueli, Karin; ... Kirkham, Fenella J; + view all (2022) Brain volume in Tanzanian children with sickle cell anaemia: A neuroimaging study. British Journal of Haematology 10.1111/bjh.18503. (In press). Green open access
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Jacob, Mboka; Stotesbury, Hanne; Kija, Edward; Saunders, Dawn; Mtei, Rachel J; Tutuba, Hilda; Masanu, Upendo; ... Makani, Julie; + view all (2022) Effect of age, cerebral infarcts, vasculopathy and haemoglobin on cognitive function, in Tanzanian children with sickle cell anaemia. European Journal of Paediatric Neurology , 37 pp. 105-113. 10.1016/j.ejpn.2022.01.010. Green open access
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Jacob, M; Saunders, DE; Kawadler, JM; Mussa, B; Murdoch, R; Lapidaire, W; Tluway, F; ... Kirkham, FJ; + view all (2018) Neuroimaging in patients with sickle cell anemia: capacity building in Africa. Blood Advances , 2 (Suppl 1) pp. 26-29. 10.1182/bloodadvances.2018GS112714. Green open access
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Jacob, M; Saunders, DE; Sangeda, RZ; Ahmed, M; Tutuba, H; Kussaga, F; Musa, B; ... Kirkham, FJ; + view all (2019) Cerebral Infarcts and Vasculopathy in Tanzanian Children With Sickle Cell Anemia. Pediatric Neurology 10.1016/j.pediatrneurol.2019.12.008. (In press). Green open access
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Jacob, M; Stotesbury, H; Kawadler, JM; Lapadaire, W; Saunders, DE; Sangeda, RZ; Chamba, C; ... Clark, CA; + view all (2020) White Matter Integrity in Tanzanian Children With Sickle Cell Anemia: A Diffusion Tensor Imaging Study. Stroke 10.1161/STROKEAHA.119.027097. (In press). Green open access
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Jain, Dipty; Kirkham, Fenella J; (2023) Laboratory Associations With Transcranial Doppler Categories in Sickle Cell Disease. Indian Pediatrics , 60 (8) pp. 622-623. 10.1007/s13312-023-2957-3. Green open access
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Jiang, B; Hills, NK; Forsyth, R; Jordan, LC; Slim, M; Pavlakis, SG; Freidman, N; ... VIPS Investigators; + view all (2021) Imaging Predictors of Neurologic Outcome After Pediatric Arterial Ischemic Stroke. Stroke , 52 (1) pp. 152-161. 10.1161/STROKEAHA.120.030965. Green open access
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Jordan, LC; Williams, DOR; Rodeghier, MJ; Covert, B; Ponisio, MR; Casella, JF; McKinstry, RC; ... DeBaun, MR; + view all (2018) Children with sickle cell anemia with normal TCD and without silent infarcts have a low incidence of new strokes. American Journal of Hematology , 93 (6) pp. 760-768. 10.1002/ajh.25085. Green open access
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Juttukonda, Meher R; Vaclavu, Lena; Kirkham, Fenella J; Fields, Melanie E; Bush, Adam M; (2022) Editorial: Cerebral oxygen supply and demand in sickle cell disease: Evidence of local ischemia despite global hyperemia. Frontiers in Physiology , 13 , Article 1079889. 10.3389/fphys.2022.1079889. Green open access
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Kawadler, JM; Clark, CA; McKinstry, RC; Kirkham, FJ; (2017) Brain atrophy in paediatric sickle cell anaemia: findings from the silent infarct transfusion ( SIT) trial. [Editorial comment]. British Journal of Haematology , 177 (1) pp. 151-153. 10.1111/bjh.14039. Green open access
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Kawadler, JM; Clayden, JD; Clark, CA; Kirkham, FJ; (2016) Intelligence quotient in paediatric sickle cell disease: a systematic review and meta-analysis. Developmental Medicine & Child Neurology , 58 (7) pp. 672-679. 10.1111/dmcn.13113. Green open access
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Kawadler, JM; Slee, A; Stotesbury, H; Koelbel, M; Balfour, P; Saunders, DE; Rees, D; ... Liossi, C; + view all (2019) Index of Pain Experience in Sickle Cell Anaemia (IPESCA): development from daily pain diaries and initial findings from use with children and adults with sickle cell anaemia. British Journal of Haematology , 186 (2) pp. 360-363. 10.1111/bjh.15841. Green open access
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Kelleher, Stephanie C; Kirkham, Fenella J; Hood, Anna M; (2023) Executive Function and Processing Speed in Children Living with Sickle Cell Anemia. Children , 10 (10) , Article 1585. 10.3390/children10101585. Green open access
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Kija, EN; Saunders, DE; Munubhi, E; Darekar, A; Barker, S; Cox, TCS; Mango, M; ... Newton, CRJC; + view all (2019) Transcranial Doppler and Magnetic Resonance in Tanzanian Children With Sickle Cell Disease. Stroke , 50 (7) pp. 1719-1726. 10.1161/STROKEAHA.118.018920. Green open access
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Kirkham, Fenella J; Clayden, Jonathan D; Stotesbury, Hanne; Kawadler, Jamie M; Slee, April; Koelbel, Melanie; Saunders, Dawn E; ... Clark, Chris A; + view all (2023) Structural connectivity mediates the relationship between blood oxygenation and cognitive function in sickle cell anemia. Blood Advances , 7 (11) pp. 2297-2308. 10.1182/bloodadvances.2021006751. Green open access
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Kirkham, FJ; Lagunju, IA; (2021) Epidemiology of stroke in sickle cell disease. Journal of Clinical Medicine , 10 (18) , Article 4232. 10.3390/jcm10184232. Green open access
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Kirkham, F; Auvin, S; Moreira, J; Gama, H; Falcão, AC; Rocha, J-F; Soares-da-Silva, P; (2020) Efficacy and safety of eslicarbazepine acetate as adjunctive therapy for refractory focal-onset seizures in children: A double-blind, randomized, placebo-controlled, parallel-group, multicenter, phase-III clinical trial. Epilepsy and Behavior , 105 , Article 106962. 10.1016/j.yebeh.2020.106962. Green open access
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Kirkham, FJ; (2017) Editorial. [Editorial comment]. Current Opinion in Neurology , 30 (2) pp. 125-126. 10.1097/WCO.0000000000000428. Green open access
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Kirkham, FJ; (2017) Neurocognitive outcomes for acute global acquired brain injury in children. Current Opinion in Neurology , 30 (2) pp. 148-155. 10.1097/WCO.0000000000000427. Green open access
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Kirkham, FJ; Kawadler, JM; Clark, CA; Hales, PW; Cox, TS; Barker, S; (2018) Cerebral perfusion characteristics show differences in younger vs. older children with sickle cell anaemia: results from a multiple inflow time arterial spin labelling study. NMR in Biomedicine , 31 (6) 10.1002/nbm.3915. Green open access
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Kirkham, FJ; Keylock, A; Saunders, D; (2018) Stroke in childhood neurofibromatosis type 2. Developmental Medicine and Child Neurology , 60 (12) pp. 1199-1200. 10.1111/dmcn.13965. Green open access
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Kirkham, FJ; Shmueli, K; (2018) Brain iron in sickle cell disease? [Editorial comment]. Blood , 132 (15) pp. 1550-1552. 10.1182/blood-2018-08-867010. Green open access
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Kirkham, FJ; Vigevano, F; Raspall-Chaure, M; Wilken, B; Lee, D; Le Reun, C; Werner-Kiechle, T; (2020) Health-related quality of life and the burden of prolonged seizures in noninstitutionalized children with epilepsy. Epilepsy and Behavior , 102 , Article 106340. 10.1016/j.yebeh.2019.04.058. Green open access
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Kirkham, FJ; Zafeiriou, D; Howe, D; Czarpran, P; Harris, A; Gunny, R; Vollmer, B; (2018) Fetal stroke and cerebrovascular disease: Advances in understanding from lenticulostriate and venous imaging, alloimmune thrombocytopaenia and monochorionic twins. European Journal of Paediatric Neurology , 22 (6) pp. 989-1005. 10.1016/j.ejpn.2018.08.008. Green open access
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Koelbel, Melanie; Hamdule, Shifa; Kirkham, Fenella J; Stotesbury, Hanne; Hood, Anna Marie; Dimitriou, Dagmara; (2023) Mind the gap: trajectory of cognitive development in young individuals with sickle cell disease: a cross-sectional study. Frontiers in Neurology , 14 , Article 1087054. 10.3389/fneur.2023.1087054. Green open access
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Kölbel, M; Kirkham, FJ; Dimitriou, D; (2020) Developmental Profile of Sleep and Its Potential Impact on Daytime Functioning from Childhood to Adulthood in Sickle Cell Anaemia. Brain Sciences , 10 (12) , Article 981. 10.3390/brainsci10120981. Green open access
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Kupferman, JC; Zafeiriou, DI; Lande, MB; Kirkham, FJ; Pavlakis, SG; (2017) Stroke and Hypertension in Children and Adolescents. Journal of Child Neurology , 32 (4) pp. 408-417. 10.1177/0883073816685240. Green open access
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L'Esperance, VS; Ekong, T; Cox, SE; Makani, J; Newton, CR; Soka, D; Komba, A; ... Hill, CM; + view all (2016) Nocturnal haemoglobin oxygen desaturation in urban and rural East African paediatric cohorts with and without sickle cell anaemia: a cross-sectional study. Archives of Disease in Childhood , 101 (4) pp. 352-355. 10.1136/archdischild-2014-306468. Green open access
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Lim, ST; Thijs, V; Murphy, SJX; Fernandez-Cadenas, I; Montaner, J; Offiah, C; Marquardt, L; ... McCabe, DJH; + view all (2020) Platelet function/reactivity testing and prediction of risk of recurrent vascular events and outcomes after TIA or ischaemic stroke: systematic review and meta-analysis. Journal of Neurology , 267 pp. 3021-3037. 10.1007/s00415-020-09932-y. Green open access
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Makani, J; Cox, SE; Soka, D; Komba, AN; Oruo, J; Mwamtemi, H; Magesa, P; ... Newton, CR; + view all (2011) Mortality in Sickle Cell Anemia in Africa: A Prospective Cohort Study in Tanzania. PLOS ONE , 6 (2) , Article e14699. 10.1371/journal.pone.0014699. Green open access
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Makani, J; Tluway, F; Makubi, A; Soka, D; Nkya, S; Sangeda, R; Mgaya, J; ... Mmbando, BP; + view all (2018) A ten year review of the sickle cell program in Muhimbili National Hospital, Tanzania. BMC Hematology , 18 (33) 10.1186/s12878-018-0125-0. Green open access
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Murdoch, Russell; Stotesbury, Hanne; Hales, Patrick W; Kawadler, Jamie M; Kölbel, Melanie; Clark, Christopher A; Kirkham, Fenella J; (2022) A Comparison of MRI Quantitative Susceptibility Mapping and TRUST-Based Measures of Brain Venous Oxygen Saturation in Sickle Cell Anaemia. Frontiers in Psychology , 13 , Article 913443. 10.3389/fphys.2022.913443. Green open access
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Nkya, S; Mgaya, J; Urio, F; Makubi, A; Thein, SL; Menzel, S; Cox, SE; ... Makani, J; + view all (2017) Fetal Hemoglobin is Associated with Peripheral Oxygen Saturation in Sickle Cell Disease in Tanzania. EBioMedicine 10.1016/j.ebiom.2017.08.006. (In press). Green open access
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O'Callaghan, FJK; Edwards, SW; Dietrich Alber, F; Cortina Borja, M; Hancock, E; Johnson, AL; Kennedy, CR; ... Osborne, JP; + view all (2018) Vigabatrin with hormonal treatment versus hormonal treatment alone (ICISS) for infantile spasms: 18-month outcomes of an open-label, randomised controlled trial. The Lancet Child & Adolescent Health , 2 (10) pp. 715-725. 10.1016/S2352-4642(18)30244-X. Green open access
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O'Cathail, SM; Wu, C-H; Lewis, A; Holmes, C; Hawkins, MA; Maughan, T; (2020) NRF2 metagene signature is a novel prognostic biomarker in colorectal cancer. Cancer Genetics , 248-49 pp. 1-10. 10.1016/j.cancergen.2020.08.006. Green open access
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Padarti, Akhil; Quinn, Charles T; Kwiatkowski, Janet L; McNaull, Melissa; Kirkham, Fenella J; Plumb, Patricia; Hynan, Linda S; ... PFAST Investigators; + view all (2025) Prevalence of Antiplatelet and Anticoagulation Therapy in Children with Sickle Cell Anemia and Stroke. Pediatric Stroke , 11 pp. 111-140. (In press).

Prussien, KV; Salihu, A; Abdullahi, SU; Galadanci, NA; Bulama, K; Belonwu, RO; Kirkham, FJ; ... Compas, BE; + view all (2018) Associations of transcranial doppler velocity, age, and gender with cognitive function in children with sickle cell anemia in Nigeria. Child Neuropsychology , 25 (6) pp. 705-720. 10.1080/09297049.2018.1526272. Green open access
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Rosen, CL; Debaun, MR; Strunk, RC; Redline, S; Seicean, S; Craven, DI; Gavlak, JCD; ... Kirkham, FJ; + view all (2014) Obstructive Sleep Apnea and Sickle Cell Anemia. Pediatrics , 134 (2) pp. 273-281. 10.1542/peds.2013-4223. Green open access
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Sankar, R; Kirkham, FJ; Holmes, GL; Pina-Garza, JE; Wheless, J; Gama, H; Moreira, J; ... Grinnell, T; + view all (2020) Long-term safety and tolerability of adjunctive eslicarbazepine acetate in children with focal seizures. Epilepsy and Behavior , 112 , Article 107458. 10.1016/j.yebeh.2020.107458. Green open access
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Saposnik, Gustavo; Bushnell, Cheryl; Coutinho, Jonathan M; Field, Thalia S; Furie, Karen L; Galadanci, Najibah; Kam, Wayneho; ... American Heart Association Stroke Council; Council on Cardiopulm; + view all (2024) Diagnosis and Management of Cerebral Venous Thrombosis: A Scientific Statement From the American Heart Association. Stroke , 55 (3) , Article 2744. 10.1161/STR.0000000000000456. Green open access
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Scholefield, BR; Menzies, JC; McAnuff, J; Thompson, JY; Manning, JC; Feltbower, RG; Geary, M; ... Rapley, T; + view all (2023) Implementing early rehabilitation and mobilisation for children in UK paediatric intensive care units: the PERMIT feasibility study. Health Technology Assessment , 27 (27) vii-129. 10.3310/HYRW5688. Green open access
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Stewart, J-AT; Willen, SM; Cohen, R; Rodeghier, M; Kirkham, F; Redline, SS; Rosen, C; ... DeBaun, MR; + view all (2019) BMI percentile is an independent predictor of increase in lung function in children with sickle cell anemia. American Journal of Hematology , 94 (5) E136-E138. 10.1002/ajh.25433. Green open access
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Stotesbury, H; Hales, PW; Koelbel, M; Hood, AM; Kawadler, JM; Saunders, DE; Sahota, S; ... Kirkham, FJ; + view all (2022) Venous cerebral blood flow quantification and cognition in patients with sickle cell anemia. Journal of Cerebral Blood Flow & Metabolism 10.1177/0271678X211072391. (In press). Green open access
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Stotesbury, H; Kawadler, JM; Saunders, DE; Kirkham, FJ; (2021) MRI detection of brain abnormality in sickle cell disease. Expert Review of Hematology , 14 (5) pp. 473-491. 10.1080/17474086.2021.1893687. Green open access
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Stotesbury, Hanne; Hales, Patrick W; Hood, Anna M; Koelbel, Melanie; Kawadler, Jamie M; Saunders, Dawn E; Sahota, Sati; ... Kirkham, Fenella J; + view all (2022) Individual Watershed Areas in Sickle Cell Anemia: An Arterial Spin Labeling Study. Frontiers in Physiology , 13 , Article 865391. 10.3389/fphys.2022.865391. Green open access
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Stotesbury, Hanne; Hales, Patrick W; Kirkham, Fenella J; (2018) The promise of noninvasive cerebral hemodynamic assessment in sickle cell anemia. Neurology , 90 (13) pp. 585-586. 10.1212/WNL.0000000000005236. Green open access
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Stotesbury, Hanne; Kawadler, Jamie M; Clayden, Jonathan D; Saunders, Dawn E; Hood, Anna M; Koelbel, Melanie; Sahota, Sati; ... Kirkham, Fenella J; + view all (2022) Quantification of Silent Cerebral Infarction on High-Resolution FLAIR and Cognition in Sickle Cell Anemia. Frontiers in Neurology , 13 , Article 867329. 10.3389/fneur.2022.867329. Green open access
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Stotesbury, H; Kawadler, JM; Hales, PW; Saunders, DE; Clark, CA; Kirkham, FJ; (2019) Vascular Instability and Neurological Morbidity in Sickle Cell Disease: An Integrative Framework. Frontiers in Neurology , 10 , Article 871. 10.3389/fneur.2019.00871. Green open access
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Stotesbury, H; Kirkham, F; Koelbel, M; Balfour, P; Clayden, J; Sahota, S; Sarkaria, S; ... Kawadler, J; + view all (2018) White Matter Integrity and Processing Speed in Sickle Cell Anemia. Neurology , 90 (23) e2042-e2050. 10.1212/WNL.0000000000005644. Green open access
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Tewari, S; Renney, G; Brewin, J; Gardner, K; Kirkham, F; Inusa, B; Barrett, JE; ... Reese, DC; + view all (2018) Proteomic analysis of plasma from children with sickle cell anemia and silent cerebral infarction. Haematologica , 103 (7) pp. 1136-1142. 10.3324/haematol.2018.187815. Green open access
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Tho-Calvi, S; Thompson, D; Saunders, D; Agrawal, S; Basu, A; Chitre, M; Chow, G; ... Ganesan, V; + view all (2018) Clinical features, course, and outcomes of a UK cohort of pediatric moyamoya. Neurology , 90 (9) e763-e767. 10.1212/WNL.0000000000005026. Green open access
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Thompson, Jacqueline Y; Menzies, Julie C; Manning, Joseph C; McAnuff, Jennifer; Brush, Emily Clare; Ryde, Francesca; Rapley, Tim; ... Scholefield, Barnaby R; + view all (2022) Early mobilisation and rehabilitation in the PICU: a UK survey. BMJ Paediatrics Open , 6 (1) , Article e001300. 10.1136/bmjpo-2021-001300. Green open access
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Veggiotti, P; Józwiak, S; Kirkham, F; Moreira, J; Pereira, A; Ikedo, F; Gama, H; (2022) Long-term therapeutic effect of eslicarbazepine acetate in children: An open-label extension of a cognition study in children aged 6-16 years. Epilepsy & Behavior , 127 , Article 108515. 10.1016/j.yebeh.2021.108515. (In press). Green open access
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Vigevano, F; Kirkham, FJ; Wilken, B; Raspall-Chaure, M; Grebla, R; Lee, D; Werner-Kiechle, T; (2018) Effect of rescue medication on seizure duration in non-institutionalized children with epilepsy. European Journal of Paediatric Neurology , 22 (1) pp. 56-63. 10.1016/j.ejpn.2017.07.017. Green open access
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Walker, Elise J; Kirkham, Fenella J; Stotesbury, Hanne; Dimitriou, Dagmara; Hood, Anna M; (2023) Tele-neuropsychological Assessment of Children and Young People: A Systematic Review. Journal of Pediatric Neuropsychology 10.1007/s40817-023-00144-6. (In press). Green open access
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Walker, Elise Jade; Kirkham, Fenella Jane; Hood, Anna Marie; (2024) Decline in Processing Speed Tells Only Half the Story: Developmental Delay in Children Living with Sickle Cell Disease. Children , 11 (3) , Article 277. 10.3390/children11030277. Green open access
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Willen, SM; Cohen, R; Rodeghier, M; Kirkham, F; Redline, SS; Rosen, C; Kirkby, J; (2018) Age is the only predictor of small decrease in lung function in children with sickle cell anemia. American Journal of Hematology , 93 (3) pp. 408-415. 10.1002/ajh.25003. Green open access
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Willen, SM; Rodeghier, M; Strunk, RC; Bacharier, LB; Rosen, CL; Kirkham, FJ; DeBaun, MR; (2018) Aeroallergen sensitization predicts acute chest syndrome in children with sickle cell anaemia. British Journal of Haematology , 180 (4) pp. 571-577. 10.1111/bjh.15076. Green open access
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Willen, SM; Rodeghier, M; Strunk, RC; Rosen, CL; Kirkham, FJ; Field, JJ; DeBaun, MR; (2017) Airway Hyperresponsiveness Does Not Predict Morbidity in Children with Sickle Cell Anemia. American Journal of Respiratory and Critical Care Medicine , 195 (11) pp. 1533-1534. 10.1164/rccm.201610-1970LE. Green open access
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Book chapter

Kawadler, JM; Kirkham, FJ; (2016) Neurological Complications and MRI. In: Inusa, BPD, (ed.) Sickle Cell Disease - Pain and Common Chronic Complications. InTech: Rijeka, Croatia. Gold open access
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Kirkham, F; (2020) Coagulopathies. In: Rosenberg, R and Pascual, J, (eds.) Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease. (pp. 579-593). Elsevier

Kirkham, F; (2020) Sickle Cell Disease. In: Rosenberg, R and Pascual, J, (eds.) Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease. (pp. 595-609). Elsevier

Kirkham, F; Laugesaar, R; Talvik, T; Metsvaht, T; Talvik, I; (2020) Acute stroke. In: Kennedy, C, (ed.) Principles and Practice of Child Neurology in Infancy. MacKeith Press

Kirkham, F; Talviik, T; Metsvaht, T; Talviik, I; (2020) Acute non-febrile encephalopathy and traumatic brain injury. In: Kennedy, C, (ed.) Principles and Practice of Child Neurology in Infancy. MacKeith Press Green open access
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Proceedings paper

Kirkham, FJ; Abel, F; Gavlak, JC; Russo, K; Laverty, A; Kirkham, FJ; (2015) Nocturnal desaturation and proteinuria in children with sickle cell anaemia. In: Special Issue: Abstracts of the 55th Annual Scientific Meeting of the British Society for Haematology. (pp. p. 22). WILEY-BLACKWELL: Edinburgh, UK. Green open access
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Murdoch, R; Kawadler, J; Carmichael, D; Kirkham, F; Shmueli, K; (2020) Can multi-parametric mapping sequences be used for accurate quantitative susceptibility mapping? In: Proceedings of the 2020 ISMRM & SMRT VIRTUAL CONFERENCE & EXHIBITION. (pp. pp. 1-3). International Society for Magnetic Resonance in Medicine (ISMRM) Green open access
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Murdoch, R; Kawadler, J; Kirkham, F; Shmueli, K; (2019) MRI susceptibility mapping suggests elevated brain iron in sickle cell anaemia. In: Proceedings of the ISMRM 27th Annual Meeting & Exhibition. SMRT 28th Annual Meeting. (pp. pp. 1-3). International Society for Magnetic Resonance in Medicine (ISMRM) Green open access
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Murdoch, R; Kawadler, J; Kirkham, F; Shmueli, K; (2018) Investigating the effect of prior stroke on regional brain iron concentrations in children with sickle cell anaemia using MRI susceptibility mapping. In: Proceedings of the Joint Annual Meeting ISMRM-ESMRMB 2018. SMRT 27th Annual Meeting. (pp. pp. 1-3). : International Society for Magnetic Resonance in Medicine (ISMRM). Green open access
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Murdoch, R; Stotesbury, H; Kawadler, J; Kirkham, F; Shmueli, K; (2019) MRI susceptibility mapping shows decreased venous oxygen saturation in sickle cell anaemia. In: Proceedings of the ISMRM 27th Annual Meeting & Exhibition. SMRT 28th Annual Meeting. (pp. pp. 1-3). International Society for Magnetic Resonance in Medicine (ISMRM) Green open access
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Shmueli, K; Kawadler, J; Carmichael, D; Clark, CA; Kirkham, FJ; (2015) Susceptibility Mapping in Sickle Cell Anaemia Patients with and Without Chronic Blood Transfusions. In: Proc. Intl. Soc. Mag. Reson. Med. 23 (2015). ISMRM Green open access
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Stotesbury, H; Murdoch, R; Hales, P; Kawadler, J; Kolbel, M; Carmichael, D; Clark, C; ... Shmueli, K; + view all (2020) Venous oxygenation in sickle cell patients and controls using quantitative susceptibility mapping versus T2- relaxation-under-spin-tagging. In: Proceedings of the 2020 ISMRM & SMRT VIRTUAL CONFERENCE & EXHIBITION. (pp. pp. 1-3). International Society for Magnetic Resonance in Medicine (ISMRM) Green open access
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Conference item

deVeber, G; Kirkham, F; Brandao, LR; Sträter, R; Kenet, G; Kausch, M; Stoll, M; ... Nowak-Göttl, U; + view all (2019) Recurrent Pediatric Stroke: The Role of Thrombophilia in a Large International Pediatric Stroke Population. Presented at: 63rd Annual Meeting of the Society of Thrombosis and Haemostasis Research, Berlin, Germany. Green open access
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Jain, D; Ganesan, K; Sahota, S; Darbari, DS; Krishnamurti, L; Kirkham, FJ; (2019) Transcranial Doppler Screening in Children with Sickle Cell Anemia Is Feasible in Central India and Reveals High Risk of Stroke. Presented at: 61st ASH Annual Meeting, Orlando (FL), USA. Green open access
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Kolbel, M; Stotesbury, H; Kawadler, J; Howard, J; Inusa, B; Rees, D; Chakravorty, S; ... Slee, A; + view all (2018) Does auto-adjusting positive airway pressure (APAP) aid memory and learning in children with sickle cell disease and sleep disordered-breathing? Presented at: 58th Annual Scientific Meeting of the British-Society-for-Haematology, Liverpool, UK. Green open access
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Slee, A; Stotesbury, H; Kawadler, J; Koelbel, M; Chakravorty, S; Pelidis, M; Thein, SL; ... Kirkham, F; + view all (2018) Prevention of Morbidity in Sickle Cell Disease Phase 2 (POMS 2b pediatric): Improvement of Cognition in children with Sickle Cell Disease with Auto-adjusting Continuous Positive Airways Pressure: a single-blind, randomized, controlled phase II trial. Presented at: 58th Annual Scientific Meeting of the British-Society-for-Haematology, Liverpool, UK. Green open access
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Smith, C; Kawadler, J; Kirkham, F; Hogan, A; Telfer, P; Stotesbury, H; (2018) Residential proximity to major roads and cognitive function in asymptomatic children with Sickle Cell Anaemia: a longitudinal study. Presented at: 58th Annual Scientific Meeting of the British-Society-for-Haematology, Liverpool, UK. Green open access
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Thesis

Downes, M; (2016) The development and assessment of executive functioning in preschool children with and without sickle cell anaemia. Doctoral thesis , UCL (University College London). Green open access
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This list was generated on Sun Feb 1 06:13:10 2026 GMT.