Murdoch, R;
Kawadler, J;
Carmichael, D;
Kirkham, F;
Shmueli, K;
(2020)
Can multi-parametric mapping sequences be used for accurate quantitative susceptibility mapping?
In:
Proceedings of the 2020 ISMRM & SMRT VIRTUAL CONFERENCE & EXHIBITION.
(pp. pp. 1-3).
International Society for Magnetic Resonance in Medicine (ISMRM)
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Abstract
We compared the results of Quantitative Susceptibility Mapping (QSM) in each of the Proton Density (PD-), Magnetization Transfer (MT-) and T1-weighted Multi-Echo Gradient-Echo (ME-GRE) sequences in Multi-Parametric Mapping (MPM) with QSM from a conventional ME-GRE sequence. In deep grey matter (GM) regions, we found significant susceptibility (χ) correlations between each sequence pair. Correlation coefficients were lower in white matter (WM), particularly in T1-w and MT-w sequences. Averaging χ over MPM sequences increased correlations in WM and reduced noise in GM and WM. Whole-brain χ difference maps showed the largest χ differences in and around large veins and air spaces.
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