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Diagnosis and Management of Cerebral Venous Thrombosis: A Scientific Statement From the American Heart Association

Saposnik, Gustavo; Bushnell, Cheryl; Coutinho, Jonathan M; Field, Thalia S; Furie, Karen L; Galadanci, Najibah; Kam, Wayneho; ... American Heart Association Stroke Council; Council on Cardiopulm; + view all (2024) Diagnosis and Management of Cerebral Venous Thrombosis: A Scientific Statement From the American Heart Association. Stroke , 55 (3) , Article 2744. 10.1161/STR.0000000000000456. Green open access

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Abstract

Cerebral venous thrombosis accounts for 0.5% to 3% of all strokes. The most vulnerable populations include young individuals, women of reproductive age, and patients with a prothrombotic state. The clinical presentation of cerebral venous thrombosis is diverse (eg, headaches, seizures), requiring a high level of clinical suspicion. Its diagnosis is based primarily on magnetic resonance imaging/magnetic resonance venography or computed tomography/computed tomographic venography. The clinical course of cerebral venous thrombosis may be difficult to predict. Death or dependence occurs in 10% to 15% of patients despite intensive medical treatment. This scientific statement provides an update of the 2011 American Heart Association scientific statement for the diagnosis and management of cerebral venous thrombosis. Our focus is on advances in the diagnosis and management decisions of patients with suspected cerebral venous thrombosis. We discuss evidence for the use of anticoagulation and endovascular therapies and considerations for craniectomy. We also provide an algorithm to optimize the management of patients with cerebral venous thrombosis and those with progressive neurological deterioration or thrombus propagation despite maximal medical therapy.

Type: Article
Title: Diagnosis and Management of Cerebral Venous Thrombosis: A Scientific Statement From the American Heart Association
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1161/STR.0000000000000456
Publisher version: http://dx.doi.org/10.1161/str.0000000000000456
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: AHA Scientific Statements, anticoagulants, headaches, intracranial thrombosis, seizure, sinus thrombosis, venous thrombosis
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10186797
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