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Number of items: 119.
Article
Abbosh, C;
Swanton, C;
Birkbak, NJ;
(2018)
Circulating tumor DNA analyses reveal novel resistance mechanisms to CDK inhibition in metastatic breast cancer.
Annals of Oncology
10.1093/annonc/mdy017.
(In press).
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Abdollah, MRA;
Carter, TJ;
Jones, C;
Kalber, TL;
Rajkumar, V;
Tolner, B;
Gruettner, C;
... Chester, KA; + view all
(2018)
Fucoidan Prolongs the Circulation Time of Dextran-Coated Iron Oxide Nanoparticles.
ACS Nano
, 12
(2)
pp. 1156-1169.
10.1021/acsnano.7b06734.
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Abou-Alfa, G;
Qin, S;
Ryoo, B-Y;
Lu, S-N;
Yen, C-J;
Feng, Y-H;
Lim, HY;
... Chen, L-T; + view all
(2018)
Phase III randomized study of second line ADI-PEG 20 plus best supportive care versus placebo plus best supportive care in patients with advanced hepatocellular carcinoma.
Annals of Oncology
, 29
(6)
pp. 1402-1408.
10.1093/annonc/mdy101.
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Abou-Alfa, GK;
Meyer, T;
Cheng, A-L;
El-Khoueiry, AB;
Rimassa, L;
Ryoo, B-Y;
Cicin, I;
... Kelley, RK; + view all
(2018)
Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma.
New England Journal of Medicine
, 379
(1)
pp. 54-63.
10.1056/NEJMoa1717002.
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Adams, R;
Brown, E;
Brown, L;
Butler, R;
Falk, S;
Fisher, D;
Kaplan, R;
... FOCUS4 Trial Investigators; + view all
(2018)
Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial.
The Lancet Gastroenterology & Hepatology
, 3
(3)
pp. 162-171.
10.1016/S2468-1253(17)30394-1.
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Agerbæk, MØ;
Bang-Christensen, SR;
Yang, M-H;
Clausen, TM;
Pereira, MA;
Sharma, S;
Ditlev, SB;
... Salanti, A; + view all
(2018)
The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner.
Nature Communications
, 9
(1)
, Article 3279. 10.1038/s41467-018-05793-2.
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Alexandrou, C;
Al-Aqbi, SS;
Higgins, JA;
Boyle, W;
Karmokar, A;
Andreadi, C;
Luo, J-L;
... Rufini, A; + view all
(2018)
Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes.
Scientific Reports
, 8
, Article 12096. 10.1038/s41598-018-30591-7.
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Alrifai, D;
Forster, MD;
Janes, SM;
(2018)
Emerging resistance pathways in lung cancer: what has ROS-1 taught us?
[Editorial comment].
Translational Lung Cancer Research
, 7
(Suppl 1)
S9-S12.
10.21037/tlcr.2017.11.13.
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Arkenau, H-T;
Italiano, A;
Mak, G;
Toulmonde, M;
Baird, RD;
Garcia-Corbacho, J;
Plummer, R;
... Spicer, J; + view all
(2018)
An extended phase Ib study of epertinib, an orally active reversible dual EGFR/HER2 tyrosine kinase inhibitor, in patients with solid tumours.
European Journal of Cancer
, 103
pp. 17-23.
10.1016/j.ejca.2018.07.134.
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Attard, G;
Borre, M;
Gurney, H;
Loriot, Y;
Andresen-Daniil, C;
Kalleda, R;
Trinh, P;
(2018)
Abiraterone Alone or in Combination With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer With Rising Prostate-Specific Antigen During Enzalutamide Treatment.
Journal of Clinical Oncology
, 36
(25)
pp. 2639-2646.
10.1200/JCO.2018.77.9827.
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Bakhoum, SF;
Ngo, B;
Laughney, AM;
Cavallo, J-A;
Murphy, CJ;
Ly, P;
Shah, P;
... Cantley, LC; + view all
(2018)
Chromosomal instability drives metastasis through a cytosolic DNA response.
Nature
, 553
(7689)
pp. 467-472.
10.1038/nature25432.
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Barata, PC;
De Liano, AG;
Mendiratta, P;
Crolley, V;
Szabados, B;
Morrison, L;
Wood, L;
... Rini, BI; + view all
(2018)
The efficacy of VEGFR TKI therapy after progression on immune combination therapy in metastatic renal cell carcinoma.
British Journal of Cancer
, 119
(2)
pp. 160-163.
10.1038/s41416-018-0104-z.
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Belderbos, BPSI;
de Wit, R;
Chien, C;
Mitselos, A;
Hellemans, P;
Jiao, J;
Yu, MK;
... Saad, F; + view all
(2018)
An open-label, multicenter, phase Ib study investigating the effect of apalutamide on ventricular repolarization in men with castration-resistant prostate cancer.
Cancer Chemotherapy and Pharmacology
, 82
(3)
pp. 457-468.
10.1007/s00280-018-3632-6.
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Bird, TG;
Müller, M;
Boulter, L;
Vincent, DF;
Ridgway, RA;
Lopez-Guadamillas, E;
Lu, W-Y;
... Forbes, SJ; + view all
(2018)
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence.
Science Translational Medicine
, 10
(454)
, Article eaan1230. 10.1126/scitranslmed.aan1230.
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Birley, K;
Chester, K;
Anderson, J;
(2018)
Antibody based therapy for childhood solid cancers.
Current Opinion in Chemical Engineering
, 19
pp. 153-162.
10.1016/j.coche.2018.01.005.
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Blas, P;
Tolner, B;
Ward, J;
Chester, K;
Hoare, M;
(2018)
The use of a surface active agent in the protection of a fusion protein during bioprocessing.
Biotechnology and Bioengineering
, 115
(11)
pp. 2760-2770.
10.1002/bit.26817.
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Böiers, C;
Richardson, SE;
Laycock, E;
Zriwil, A;
Turati, VA;
Brown, J;
Wray, JP;
... Enver, T; + view all
(2018)
A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1.
Developmental Cell
, 44
(3)
pp. 362-377.
10.1016/j.devcel.2017.12.005.
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Brandner, SGP;
Jaunmuktane, Z;
Capper, D;
Jones, DTW;
Sill, M;
Hovestadt, V;
Schrimpf, D;
... Pfister, SM; + view all
(2018)
DNA methylation-based classification of central nervous system tumours.
Nature. International Journal of Science
, 555
pp. 469-474.
10.1038/nature26000.
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Brown, NF;
Williams, M;
Arkenau, H-T;
Fleming, RA;
Tolson, J;
Yan, L;
Zhang, J;
... Mulholland, P; + view all
(2018)
A study of the focal adhesion kinase inhibitor GSK2256098 in patients with recurrent glioblastoma with evaluation of tumor penetration of [¹¹C]GSK2256098.
Neuro-Oncology
, 20
(12)
pp. 1634-1642.
10.1093/neuonc/noy078.
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Capper, D;
Engel, NW;
Stichel, D;
Lechner, M;
Gloess, S;
Schmid, S;
Koelsche, C;
... Schueller, U; + view all
(2018)
DNA methylation-based reclassification of olfactory neuroblastoma.
Acta Neuropathologica
, 136
(2)
pp. 255-271.
10.1007/s00401-018-1854-7.
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Casali, PG;
Bielack, S;
Abecassis, N;
Aro, HT;
Bauer, S;
Biagini, R;
Bonvalot, S;
... Blay, JY; + view all
(2018)
Bone sarcomas: ESMO–PaedCan–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Annals of Oncology
, 29
(4)
pp. 79-95.
10.1093/annonc/mdy310.
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Chakravarthy, A;
Furness, A;
Joshi, K;
Ghorani, E;
Ford, K;
Ward, MJ;
King, EV;
... Fenton, TR; + view all
(2018)
Author Correction: Pan-cancer deconvolution of tumour composition using DNA methylation.
[Corrigendum].
Nature Communications
, 9
, Article 4642. 10.1038/s41467-018-07155-4.
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Chakravarthy, A;
Furness, A;
Joshi, K;
Ghorani, E;
Ford, K;
Ward, MJ;
King, EV;
... Fenton, TR; + view all
(2018)
Pan-cancer deconvolution of tumour composition using DNA methylation.
Nature Communications
, 9
, Article 3220. 10.1038/s41467-018-05570-1.
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Chen, L;
Esfandiari, A;
Reaves, W;
Vu, A;
Hogarty, MD;
Lunec, J;
Tweddle, DA;
(2018)
Characterisation of the p53 pathway in cell lines established from TH-MYCN transgenic mouse tumours.
International Journal of Oncology
, 52
(3)
pp. 967-977.
10.3892/ijo.2018.4261.
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Cho, S;
Zammarchi, F;
Williams, DG;
Havenith, CE;
Monks, NR;
Tyrer, P;
d'Hooge, F;
... van Berkel, PH; + view all
(2018)
Antitumor Activity of MEDI3726 (ADCT-401), a Pyrrolobenzodiazepine Antibody-drug Conjugate Targeting PSMA, in Pre-clinical Models of Prostate Cancer.
Molecular Cancer Therapeutics
, 17
(10)
10.1158/1535-7163.MCT-17-0982.
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Claus, J;
Patel, G;
Autore, F;
Colomba, A;
Weitsman, G;
Soliman, TN;
Roberts, S;
... Parker, PJ; + view all
(2018)
Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface.
eLIFE
, 7
, Article e32271. 10.7554/eLife.32271.
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Conibear, J;
Chia, B;
Ngai, Y;
Bates, AT;
Counsell, N;
Patel, R;
Eaton, D;
... Landau, D; + view all
(2018)
Study protocol for the SARON trial: a multicentre, randomised controlled phase III trial comparing the addition of stereotactic ablative radiotherapy and radical radiotherapy with standard chemotherapy alone for oligometastatic non-small cell lung cancer.
BMJ Open
, 8
(4)
, Article e020690. 10.1136/bmjopen-2017-020690.
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Conteduca, V;
Scarpi, E;
Salvi, S;
Casadio, V;
Lolli, C;
Gurioli, G;
Schepisi, G;
... De Giorgi, U; + view all
(2018)
Plasma Androgen Receptor and Serum Chromogranin a in Advanced Prostate Cancer.
Scientific Reports
, 8
, Article 15442. 10.1038/s41598-018-33774-4.
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Cope, AP;
Barnes, MR;
Belson, A;
Binks, M;
Brockbank, S;
Bonachela-Capdevila, F;
Carini, C;
... RA-MAP Consortium; + view all
(2018)
The RA-MAP Consortium: a working model for academia-industry collaboration.
Nature Reviews Rheumatology
, 14
(1)
pp. 53-60.
10.1038/nrrheum.2017.200.
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Davidson, SM;
Riquelme, JA;
Zheng, Y;
Vicencio, JM;
Lavandero, S;
Yellon, DM;
(2018)
Endothelial cells release cardioprotective exosomes that may contribute to ischaemic preconditioning.
Scientific Reports
, 8
, Article 15885. 10.1038/s41598-018-34357-z.
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de Carcer, G;
Venkateswaran, SV;
Salgueiro, L;
El Bakkali, A;
Somogyi, K;
Rowald, K;
Montanes, P;
... Sotillo, R; + view all
(2018)
Plk1 overexpression induces chromosomal instability and suppresses tumor development.
Nature Communications
, 9
, Article 3012. 10.1038/s41467-018-05429-5.
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Dillon, MT;
Boylan, Z;
Smith, D;
Guevara, J;
Mohammed, K;
Peckitt, C;
Saunders, M;
... Harrington, KJ; + view all
(2018)
PATRIOT: A phase I study to assess the tolerability, safety and biological effects of a specific ataxia telangiectasia and Rad3-related (ATR) inhibitor (AZD6738) as a single agent and in combination with palliative radiation therapy in patients with solid tumours.
Clinical and Translational Radiation Oncology
, 12
pp. 16-20.
10.1016/j.ctro.2018.06.001.
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Dirix, LY;
Takacs, I;
Jerusalem, G;
Nikolinakos, P;
Arkenau, H-T;
Forero-Torres, A;
Boccia, R;
... Hamilton, EP; + view all
(2018)
Avelumab, an anti-PD-L1 antibody, in patients with locally advanced or metastatic breast cancer: a phase 1b JAVELIN Solid Tumor study.
Breast Cancer Research and Treatment
, 167
(3)
pp. 671-686.
10.1007/s10549-017-4537-5.
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Forster, M;
Hackshaw, A;
De Pas, T;
Cobo, M;
Garrido, P;
Summers, Y;
Dingemans, AMC;
... Lee, SM; + view all
(2018)
A phase I study of nintedanib combined with cisplatin/gemcitabine as first-line therapy for advanced squamous non-small cell lung cancer (LUME-Lung 3).
Lung Cancer
, 120
pp. 27-33.
10.1016/j.lungcan.2018.03.007.
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Forster, MD;
Devlin, M-J;
(2018)
Immune Checkpoint Inhibition in Head and Neck Cancer.
Frontiers in Oncology
, 8
, Article 310. 10.3389/fonc.2018.00310.
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Forte, N;
Livanos, M;
Miranda, E;
Morais, M;
Yang, X;
Rajkumar, VS;
Chester, KA;
... Baker, JR; + view all
(2018)
Tuning the Hydrolytic Stability of Next Generation Maleimide Cross-Linkers Enables Access to Albumin-Antibody Fragment Conjugates and tri-scFvs.
Bioconjugate Chemistry
, 29
(2)
pp. 486-492.
10.1021/acs.bioconjchem.7b00795.
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Ghorani, E;
Rosenthal, R;
McGranahan, N;
Reading, JL;
Lynch, M;
Peggs, KS;
Swanton, C;
(2018)
Differential binding affinity of mutated peptides for MHC class I is a predictor of survival in advanced lung cancer and melanoma.
Annals of Oncology
, 29
(1)
pp. 271-279.
10.1093/annonc/mdx687.
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Gillessen, S;
Attard, G;
Beer, TM;
Beltran, H;
Bossi, A;
Bristow, R;
Carver, B;
... Omlin, A; + view all
(2018)
Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017.
European Urology
, 73
(2)
pp. 178-211.
10.1016/j.eururo.2017.06.002.
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Grieco, G;
Janssens, V;
Chevronnay, HPG;
N'Kuli, F;
Van Der Smissen, P;
Wang, T;
Shan, J;
... Courtoy, PJ; + view all
(2018)
Vps34/PI3KC3 deletion in kidney proximal tubules impairs apical trafficking and blocks autophagic flux, causing a Fanconi-like syndrome and renal insufficiency.
Scientific Reports
, 8
, Article 14133. 10.1038/s41598-018-32389-z.
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Gurusamy, K;
Corrigan, N;
Croft, J;
Twiddy, M;
Morris, S;
Woodward, N;
Bandula, S;
... Davidson, BR; + view all
(2018)
Liver resection surgery versus thermal ablation for colorectal LiVer MetAstases (LAVA): study protocol for a randomised controlled trial.
Trials
, 19
, Article 105. 10.1186/s13063-018-2499-5.
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Hainsworth, JD;
Meric-Bernstam, F;
Swanton, C;
Hurwitz, H;
Spigel, DR;
Sweeney, C;
Burris, H;
... Kurzrock, R; + view all
(2018)
Targeted Therapy for Advanced Solid Tumors on the Basis of Molecular Profiles: Results From MyPathway, an Open-Label, Phase IIa Multiple Basket Study.
Journal of Clinical Oncology
, 36
(6)
pp. 536-544.
10.1200/JCO.2017.75.3780.
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Hartley, JA;
Flynn, MJ;
Bingham, JP;
Corbett, S;
Reinert, H;
Tiberghien, A;
Masterson, LA;
... Howard, PW; + view all
(2018)
Pre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of antibody-drug conjugate (ADC) payload tesirine.
Scientific Reports
, 8
, Article 10479. 10.1038/s41598-018-28533-4.
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Harvey, RD;
Aransay, NR;
Isambert, N;
Lee, J-S;
Arkenau, T;
Vansteenkiste, J;
Dickinson, PA;
... Vishwanathan, K; + view all
(2018)
Effect of multiple-dose osimertinib on the pharmacokinetics of simvastatin and rosuvastatin.
British Journal of Clinical Pharmacology
, 84
(12)
pp. 2877-2888.
10.1111/bcp.13753.
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Hellmann, MD;
Nathanson, T;
Rizvi, H;
Creelan, BC;
Sanchez-Vega, F;
Ahuja, A;
Ni, A;
... Wolchok, JD; + view all
(2018)
Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.
Cancer Cell
, 33
(5)
843-852.e4.
10.1016/j.ccell.2018.03.018.
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Holme, H;
Gulati, A;
Brough, R;
Fleuren, EDG;
Bajrami, I;
Campbell, J;
Chong, IY;
... Lord, CJ; + view all
(2018)
Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness.
Scientific Reports
, 8
, Article 10614. 10.1038/s41598-018-29043-z.
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Howie, AJ;
(2018)
Genetic studies of focal segmental glomerulosclerosis: a waste of scientific time?
Pediatric Nephrology
10.1007/s00467-018-4161-6.
(In press).
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Hudson, A;
Chan, C;
Woolf, D;
McWilliam, A;
Hiley, C;
O'Connor, J;
Bayman, N;
... Faivre-Finn, C; + view all
(2018)
Is heterogeneity in stage 3 non-small cell lung cancer obscuring the potential benefits of dose-escalated concurrent chemo-radiotherapy in clinical trials?
Lung Cancer
, 118
pp. 139-147.
10.1016/j.lungcan.2018.02.006.
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Hynds, RE;
Ben Aissa, A;
Gowers, KHC;
Watkins, TBK;
Bosshard-Carter, L;
Rowan, AJ;
Veeriah, S;
... Janes, SM; + view all
(2018)
Expansion of airway basal epithelial cells from primary human non-small cell lung cancer tumors.
International Journal of Cancer
, 143
(1)
pp. 160-166.
10.1002/ijc.31383.
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Hynds, RE;
Gowers, KHC;
Nigro, E;
Butler, CR;
Bonfanti, P;
Giangreco, A;
Prele, CM;
(2018)
Cross-talk between human airway epithelial cells and 3T3-J2 feeder cells involves partial activation of human MET by murine HGF.
PLoS ONE
, 13
(5)
, Article e0197129. 10.1371/journal.pone.0197129.
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Hynds, RE;
Vladimirou, E;
Janes, SM;
(2018)
The secret lives of cancer cell lines.
[Editorial comment].
Disease Models and Mechanisms
, 11
, Article dmm037366. 10.1242/dmm.037366.
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Jayaram, A;
Wetterskog, K;
Attard, G;
(2018)
Plasma DNA and Metastatic Castration-Resistant Prostate Cancer: The Odyssey to a Clinical Biomarker Test.
Cancer Discovery
, 8
(4)
pp. 392-294.
10.1158/2159-8290.CD-18-0124.
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Jepson, M;
Elliott, D;
Conefrey, C;
Wade, J;
Rooshenas, L;
Wilson, C;
Beard, D;
... OPTIMA prelim study group, .; + view all
(2018)
An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment.
Journal of Clinical Epidemiology
, 99
pp. 75-83.
10.1016/j.jclinepi.2018.02.018.
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Kiakos, K;
Englinger, B;
Yanow, SK;
Wernitznig, D;
Jakupec, MA;
Berger, W;
Keppler, BK;
... Patil, PC; + view all
(2018)
Design, synthesis, nuclear localization, and biological activity of a fluorescent duocarmycin analog, HxTfA.
Bioorganic & Medicinal Chemistry Letters
, 28
(8)
pp. 1342-1347.
10.1016/j.bmcl.2018.03.016.
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Koch, C;
Schwing, AM;
Herrmann, E;
Borner, M;
Diaz-Rubio, E;
Dotan, E;
Feliu, J;
... Trojan, J; + view all
(2018)
Bevacizumab-based first-line chemotherapy in elderly patients with metastatic colorectal cancer: an individual patient data based meta-analysis.
Oncotarget
, 9
(12)
pp. 10272-10283.
10.18632/oncotarget.23475.
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Krol, I;
Castro-Giner, F;
Maurer, M;
Gkountela, S;
Szczerba, BM;
Scherrer, R;
Coleman, N;
... Aceto, N; + view all
(2018)
Detection of circulating tumour cell clusters in human glioblastoma.
British Journal of Cancer
, 119
pp. 487-491.
10.1038/s41416-018-0186-7.
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Laurent, P-A;
Hechler, B;
Solinhac, R;
Ragab, A;
Cabou, C;
Anquetil, T;
Severin, S;
... Gratacap, M-P; + view all
(2018)
Impact of PI3K (Phosphoinositide 3-Kinase Alpha) Inhibition on Hemostasis and Thrombosis.
Arteriosclerosis, Thrombosis, and Vascular Biology
, 38
(9)
pp. 2041-2053.
10.1161/ATVBAHA.118.311410.
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Lawler, M;
Alsina, D;
Adams, RA;
Anderson, AS;
Brown, G;
Fearnhead, NS;
Fenwick, SW;
... Tomlinson, I; + view all
(2018)
Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer.
GUT
, 67
(1)
pp. 179-193.
10.1136/gutjnl-2017-315333.
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Lechner, M;
Chakravarthy, AR;
Walter, V;
Masterson, L;
Feber, A;
Jay, A;
Weinberger, PM;
... Fenton, TR; + view all
(2018)
Frequent HPV-independent p16/INK4A overexpression in head and neck cancer.
Oral Oncology
, 83
pp. 32-37.
10.1016/j.oraloncology.2018.06.006.
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Lechner, M;
Vassie, C;
Kavasogullari, C;
Jones, O;
Howard, J;
Masterson, L;
Fenton, T;
... Gilson, R; + view all
(2018)
A cross-sectional survey of awareness of human papillomavirus-associated oropharyngeal cancers among general practitioners in the UK.
BMJ Open
, 8
(7)
, Article e023339. 10.1136/bmjopen-2018-023339.
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Linch, M;
Attard, G;
(2018)
Prostate cancers that `Wnt' respond to abiraterone.
Annals of Oncology
, 29
(2)
pp. 290-292.
10.1093/annonc/mdx785.
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