Browse by UCL people
Group by: Type | Date
Number of items: 93.
Article
Anderson, David G;
Ferreira-Correia, Aline;
Rodrigues, Filipe B;
Byrne, Lauren M;
Wild, Edward J;
Krause, Amanda;
(2024)
Comparative analysis of neurofilament light chain in Huntington's disease like 2 and Huntington's disease.
Journal of Huntington's Disease
10.1177/18796397241300141.
(In press).
|
|
Anderson, D;
Ferreira-Correia, A;
Brogueira Rodrigues, F;
Aziz, A;
Carr, J;
Wild, E;
Margolis, R;
(2019)
Comparison of the Huntington’s disease-like 2 and Huntington’s disease clinical phenotypes.
Movement Disorders Clinical Practice
(In press).
|
|
Barkhuizen, M;
Brogueira Rodrigues, FA;
Anderson, DG;
Winkens, B;
REGISTRY Investigators of the European Huntington's Disease Netw;
Wild, EJ;
Kramer, BW;
(2018)
Perinatal insults and neurodevelopmental disorders may impact Huntington's disease age of diagnosis.
Parkinsonism and Related Disorders
, 55
pp. 55-60.
10.1016/j.parkreldis.2018.05.016.
|
 |
|
Bates, GP;
Dorsey, R;
Gusella, JF;
Hayden, MR;
Kay, C;
Leavitt, BR;
Nance, M;
... Tabrizi, SJ; + view all
(2015)
Huntington's disease.
Nature Reviews Disease Primers
, 1
, Article 15005. 10.1038/nrdp.2015.5.
|
|
|
Bjorkqvist, M;
Wild, EJ;
Thiele, J;
Silvestroni, A;
Andre, R;
Lahiri, N;
Raibon, E;
... Tabrizi, SJ; + view all
(2008)
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
Journal of Experimental Medicine
, 205
(8)
1869 - 1877.
10.1084/jem.20080178.
|
 |
|
Boeddrich, Annett;
Haenig, Christian;
Neuendorf, Nancy;
Blanc, Eric;
Ivanov, Andranik;
Kirchner, Marieluise;
Schleumann, Philipp;
... Wanker, Erich E; + view all
(2023)
A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease.
Genome Medicine
, 15
(1)
, Article 50. 10.1186/s13073-023-01206-2.
|
|
Bondulich, Marie K;
Phillips, Jemima;
Cañibano-Pico, María;
Nita, Iulia M;
Byrne, Lauren M;
Wild, Edward J;
Bates, Gillian P;
(2024)
Translatable plasma and CSF biomarkers for use in mouse models of Huntington’s disease.
Brain Communications
, 6
(1)
, Article fcae030. 10.1093/braincomms/fcae030.
(In press).
|
|
|
Bridel, C;
van Wieringen, WN;
Zetterberg, H;
Tijms, BM;
Teunissen, CE;
and the NFL Group;
Alvarez-Cermeño, JC;
... Wild, EJ; + view all
(2019)
Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis.
JAMA Neurology
10.1001/jamaneurol.2019.1534.
(In press).
|
|
Brogueira Rodrigues, F;
Byrne, L;
Lowe, A;
Tortelli, R;
Heins, M;
Flik, G;
Johnson, E;
... Wild, E; + view all
(2021)
Kynurenine pathway metabolites in cerebrospinal fluid and blood as potential biomarkers in Huntington’s disease.
Journal of Neurochemistry
10.1111/jnc.15360.
(In press).
|
|
|
Brogueira Rodrigues, F;
Byrne, L;
Tortelli, R;
Johnson, E;
Wijeratne, P;
De Vita, E;
Ghazaleh, N;
... Wild, E; + view all
(2020)
Mutant huntingtin and neurofilament light have distinct longitudinal dynamics in Huntington's disease.
Science Translational Medicine
, 12
(574)
10.1126/scitranslmed.abc2888.
|
|
|
Brogueira Rodrigues, F;
Ferreira, JJ;
Wild, EJ;
(2019)
Huntington’s Disease Clinical Trials Corner: June 2019.
Journal of Huntington's disease
, 8
(3)
pp. 363-371.
10.3233/JHD-199003.
|
|
|
Brogueira Rodrigues, F;
Quinn, L;
Wild, E;
(2019)
Huntington's Disease Clinical Trials Corner: January 2019.
Journal of Huntington's Disease
, 8
(1)
pp. 115-125.
10.3233/JHD-190001.
|
|
|
Brogueira Rodrigues, FA;
Byrne, L;
De Vita, E;
Johnson, E;
Hobbs, N;
Thornton, J;
Scahill, R;
(2019)
Cerebrospinal fluid flow dynamics in Huntington's disease evaluated by phase contrast MRI.
European Journal of Neuroscience
10.1111/ejn.14356.
(In press).
|
|
Brogueira Rodrigues, FA;
Wild, E;
(2018)
Huntington's Disease Clinical Trials Corner: August 2018.
Journal of Huntington's Disease
, 7
(3)
pp. 291-298.
10.3233/JHD-189003.
|
|
|
Brogueira Rodrigues, FA;
Wild, EJ;
(2018)
Huntington’s Disease Clinical Trials Corner: February 2018.
Journal of Huntington's Disease
, 7
(1)
pp. 89-98.
10.3233/JHD-189001.
|
|
|
Byrne, Lauren M;
Schultz, Jordan L;
Rodrigues, Filipe B;
Plas, Ellen;
Langbehn, Douglas;
Nopoulos, Peggy C;
Wild, Edward J;
(2022)
Neurofilament Light Protein as a Potential Blood Biomarker for Huntington's Disease in Children.
Movement Disorders
10.1002/mds.29027.
(In press).
|
|
Byrne, LM;
Brogueira Rodrigues, F;
Johnson, E;
Wijeratne, P;
De Vita, E;
Alexander, D;
Palermo, G;
... Wild, E; + view all
(2018)
Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington’s disease.
Science Translational Medicine
, 10
(458)
, Article eaat7108. 10.1126/scitranslmed.aat7108.
|
|
Byrne, LM;
Rodrigues, FB;
Blennow, K;
Durr, A;
Leavitt, BR;
Roos, RAC;
Scahill, RI;
... Wild, EJ; + view all
(2017)
Neurofilament light protein in blood as a potential biomarker of neurodegeneration in Huntington's disease: a retrospective cohort analysis.
The Lancet Neurology
, 16
(8)
pp. 601-609.
10.1016/S1474-4422(17)30124-2.
|
|
|
Byrne, LM;
Rodrigues, FB;
Johnson, EB;
Da Vita, E;
Blennow, K;
Scahill, RI;
Zetterberg, H;
... Wild, E; + view all
(2018)
Cerebrospinal fluid neurogranin and TREM2 in Huntington’s disease.
Scientific Reports
, Article 4260. 10.1038/s41598-018-21788-x.
|
|
|
Byrne, LM;
Wild, EJ;
(2016)
Cerebrospinal Fluid Biomarkers for Huntington's Disease.
Journal of Huntington’s Disease
, 5
(1)
pp. 1-13.
10.3233/JHD-160196.
|
|
|
Caron, Nicholas S;
Byrne, Lauren M;
Lemarie, Fanny L;
Bone, Jeffrey N;
Aly, Amirah E-E;
Ko, Seunghyun;
Anderson, Christine;
... Hayden, Michael R; + view all
(2024)
Elevated plasma and CSF neurofilament light chain concentrations are stabilized in response to mutant huntingtin lowering in the brains of Huntington's disease mice.
Translational Neurodegeneration
, 13
, Article 50. 10.1186/s40035-024-00443-8.
|
|
|
Caron, N;
Banos, R;
Yanick, C;
Aly, A;
Byrne, L;
Smith, E;
Xie, Y;
... Southwell, A; + view all
(2021)
Mutant Huntingtin Is Cleared from the Brain via Active Mechanisms in Huntington Disease.
Journal of Neuroscience
, 41
(4)
pp. 780-796.
10.1523/JNEUROSCI.1865-20.2020.
|
|
|
Dewan, Ramita;
Jaunmuktane, Zane;
Garcia-Segura, Monica Emili;
Strand, Catherine;
Wild, Edward;
Villar, Joaquin;
Dalgard, Clifton L;
... Proukakis, Christos; + view all
(2022)
CAG Somatic Instability in a Huntington Disease Expansion Carrier Presenting with a Progressive Supranuclear Palsy-like Phenotype.
Movement Disorders
10.1002/mds.29035.
|
|
Estevez-Fraga, Carlos;
Rodrigues, Filipe B;
Tabrizi, Sarah J;
Wild, Edward J;
(2022)
Huntington's disease clinical trials corner: April 2022.
Journal of Huntington's Disease
, 11
(2)
pp. 105-118.
10.3233/JHD-229002.
|
|
Estevez-Fraga, Carlos;
Sebenius, Isaac;
Hansen, Justine Y;
Haenisch, Benjamin;
Zeun, Paul;
Scahill, Rachael I;
Gregory, Sarah;
... McColgan, Peter; + view all
(2025)
Cell-specific mechanisms drive connectivity across the time course of Huntington’s disease.
Nature Communications
, 16
, Article 5519. 10.1038/s41467-025-60556-0.
|
|
Estevez-Fraga, Carlos;
Tabrizi, Sarah J;
Wild, Edward J;
(2024)
Huntington's Disease Clinical Trials Update: February 2024.
Journal of Huntington's Disease
10.3233/JHD-240017.
(In press).
|
|
Estevez-Fraga, Carlos;
Tabrizi, Sarah J;
Wild, Edward J;
(2023)
Huntington's Disease Clinical Trials Corner: July 2023.
Journal of Huntington's Disease
pp. 1-17.
10.3233/JHD-239001.
(In press).
|
|
Estevez-Fraga, Carlos;
Tabrizi, Sarah J;
Wild, Edward J;
(2022)
Huntington's Disease Clinical Trials Corner: November 2022.
Journal of Huntington's Disease
, 11
(4)
pp. 351-367.
10.3233/JHD-229006.
|
|
Farag, Mena;
Coleman, Annabelle;
Knights, Harry;
Murphy, Michael J;
Rajagopal, Sangeerthana;
Touzé, Alexiane;
Shoai, Maryam;
... Tabrizi, Sarah J; + view all
(2024)
Outcomes of Percutaneous Endoscopic Gastrostomy in Huntington's Disease at a Tertiary Center.
Movement Disorders Clinical Practice
10.1002/mdc3.14130.
(In press).
|
|
|
Flower, M;
Lomeikaite, V;
Ciosi, M;
Cumming, S;
Morales, F;
Lo, K;
Hensman Moss, D;
... Tabrizi, SJ; + view all
(2019)
MSH3 modifies somatic instability and disease severity in Huntington's and myotonic dystrophy type 1.
Brain
, 142
(7)
pp. 1876-1886.
10.1093/brain/awz115.
|
|
|
Fodale, V;
Boggio, A;
Daldin, M;
Cariulo, C;
Byrne, L;
Leavitt, B;
Wild, EJ;
... Bresciani, A; + view all
(2017)
Validation of ultrasensitive mutant huntingtin detection in human cerebrospinal fluid by single molecule counting immunoassay.
Journal of Huntington's Disease
, 6
(4)
pp. 349-361.
10.3233/JHD-170269.
|
|
Furby, Hannah;
Siadimas, Athanasios;
Rutten-Jacobs, Loes;
Rodrigues, Filipe B;
Wild, Edward J;
(2022)
Natural History and Burden of Huntington's Disease in the UK: A Population-Based Cohort Study.
European Journal of Neurology
, 29
(8)
pp. 2249-2257.
10.1111/ene.15385.
|
|
Gregory, S;
Johnson, E;
Byrne, L;
Rodrigues, F;
Henderson, A;
Moss, J;
Thomas, D;
... Wild, E; + view all
(2020)
Characterising white matter in Huntington's disease.
Movement Disorders Clinical Practice
, 7
(1)
pp. 52-60.
10.1002/mdc3.12866.
|
|
|
Griffin, BA;
Booth, MS;
Busse, M;
Wild, EJ;
Setodji, C;
Warner, JH;
Sampaio, C;
(2021)
Estimating the causal effects of modifiable, non-genetic factors on Huntington disease progression using propensity score weighting.
Parkinsonism & Related Disorders
, 83
pp. 56-62.
10.1016/j.parkreldis.2021.01.010.
|
|
Hensman Moss, DJ;
Robertson, N;
Farmer, R;
Scahill, RI;
Haider, S;
Tessari, MA;
Flynn, G;
... Tabrizi, SJ; + view all
(2017)
Quantification of huntingtin protein species in Huntington's disease patient leukocytes using optimised electrochemiluminescence immunoassays.
PLoS One
, 12
(12)
, Article e0189891. 10.1371/journal.pone.0189891.
|
|
|
Ishihara, L;
Oliveri, D;
Wild, EJ;
(2020)
Neuropsychiatric comorbidities in Huntington's and Parkinson's Disease: A United States claims database analysis.
Annals of Clinical and Translational Neurology
10.1002/acn3.51252.
(In press).
|
|
|
Johnson, EB;
Byrne, LM;
Gregory, S;
Rodrigues, FB;
Blennow, K;
Durr, A;
Leavitt, BR;
... Wild, EJ; + view all
(2018)
Neurofilament light protein in blood predicts regional atrophy in Huntington disease.
Neurology
, 90
(8)
e717-e723.
10.1212/WNL.0000000000005005.
|
|
Khetarpal, Vinod;
Herbst, Todd;
Dominguez, Celia;
Munoz-Sanjuan, Ignacio;
Sampaio, Cristina;
Marks, Bryan;
Miller, Dennis L;
... Pacifici, Robert; + view all
(2025)
Lack of evidence for kynurenine pathway dysfunction in Huntington's disease: Cerebrospinal fluid and plasma analyses from the HDClarity study.
Journal of Huntington's Disease
10.1177/18796397241301761.
(In press).
|
|
Koriath, Carolin Anna Maria;
Guntoro, Fernando;
Norsworthy, Penelope;
Dolzhenko, Egor;
Eberle, Michael;
Hensman Moss, Davina J;
Flower, Michael;
... Wild, Edward J; + view all
(2024)
Huntington’s disease phenocopy syndromes revisited: a clinical comparison and next-generation sequencing exploration.
Journal of Neurology, Neurosurgery & Psychiatry
10.1136/jnnp-2024-333602.
(In press).
|
|
|
Koriath, C;
(2018)
Predictors for a dementia gene mutation based on gene-panel next-generation sequencing of a large dementia referral series.
Molecular Psychiatry
10.1038/s41380-018-0224-0.
(In press).
|
|
|
Lipsmeier, Florian;
Simillion, Cedric;
Bamdadian, Atieh;
Tortelli, Rosanna;
Byrne, Lauren M;
Zhang, Yan-Ping;
Wolf, Detlef;
... Lindemann, Michael; + view all
(2022)
A Remote Digital Monitoring Platform to Assess Cognitive and Motor Symptoms in Huntington Disease: Cross-sectional Validation Study.
Journal of Medical Internet Research
, 24
(6)
, Article e32997. 10.2196/32997.
|
|
Lowe, AJ;
Sjödin, S;
Rodrigues, FB;
Byrne, LM;
Blennow, K;
Tortelli, R;
Zetterberg, H;
(2020)
Cerebrospinal fluid endo-lysosomal proteins as potential biomarkers for Huntington's disease.
PLoS One
, 15
(8)
, Article e0233820. 10.1371/journal.pone.0233820.
|
|
|
Maiuri, Tamara;
Bazan, Carlos Barba;
Harding, Rachel J;
Begeja, Nola;
Kam, Tae-In;
Byrne, Lauren M;
Rodrigues, Filipe B;
... Truant, Ray; + view all
(2024)
Poly ADP-ribose signaling is dysregulated in Huntington disease.
PNAS (Proceedings of the National Academy of Sciences)
, 121
(40)
, Article e2318098121. 10.1073/pnas.2318098121.
|
|
|
McNulty, P;
Pilcher, R;
Ramesh, R;
Necuiniate, R;
Hughes, A;
Farewell, D;
Holmans, P;
... Hyppönen, H; + view all
(2018)
Reduced Cancer Incidence in Huntington's Disease: Analysis in the Registry Study.
Journal of Huntington's Disease
, 7
(3)
pp. 209-222.
10.3233/JHD-170263.
|
|
|
Mitchell, CT;
Krier, I;
Arjomand, J;
Borowsky, B;
Tabrizi, SJ;
Leavitt, BR;
TRACK-HD Investigators;
(2020)
Longitudinal expression changes are weak correlates of disease progression in Huntington's disease.
Brain Communications
, 2
(2)
, Article fcaa172. 10.1093/braincomms/fcaa172.
|
|
|
Moss, DJH;
Pardinas, AF;
Langbehn, D;
Lo, K;
Leavitt, BR;
Roos, R;
Durr, A;
... Tabrizi, SJ; + view all
(2017)
Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study.
Lancet Neurology
, 16
(9)
pp. 701-711.
10.1016/S1474-4422(17)30161-8.
|
|
Moss, DJH;
Poulter, M;
Beck, J;
Hehir, J;
Polke, JM;
Campbell, T;
Adamson, G;
... Tabrizi, SJ; + view all
(2014)
C9orf72 expansions are the most common genetic cause of Huntington disease phenocopies.
Neurology
, 82
(4)
pp. 292-299.
10.1212/WNL.0000000000000061.
|
|
Orth, M;
Handley, OJ;
Schwenke, C;
Dunnett, SB;
Craufurd, D;
Ho, AK;
Wild, E;
... Investigators of the European Huntington's Disease Network, The; + view all
(2010)
Observing Huntington's Disease: the European Huntington's Disease Network's REGISTRY.
PLoS Currents Huntington Disease
, 2
RRN1184 -.
10.1371/currents.RRN1184.
|
|
|
Osborne-Crowley, K;
Andrews, SC;
Labuschagne, I;
Nair, A;
Scahill, R;
Craufurd, D;
Tabrizi, SJ;
... TRACK-HD Investigators, .; + view all
(2019)
Apathy Associated With Impaired Recognition of Happy Facial Expressions in Huntington's Disease.
Journal of the International Neuropsychological Society
, 25
(5)
pp. 453-461.
10.1017/S1355617718001224.
|
|
Rodrigues, Filipe B;
Owen, Gail;
Sathe, Swati;
Pak, Elena;
Kaur, Dipinder;
Ehrhardt, Anka G;
Lifer, Sherry;
... Wild, Edward J; + view all
(2022)
Safety and Feasibility of Research Lumbar Puncture in Huntington’s Disease: The HDClarity Cohort and Bioresource.
Journal of Huntington's Disease
, 11
(1)
pp. 59-69.
10.3233/jhd-210508.
|
|
Rodrigues, FB;
Byrne, L;
McColgan, P;
Robertson, N;
Tabrizi, SJ;
Leavitt, BR;
Zetterberg, H;
(2016)
Cerebrospinal fluid total tau concentration predicts clinical phenotype in Huntington's disease.
Journal of Neurochemistry
, 139
(1)
pp. 22-25.
10.1111/jnc.13719.
|
|
Rodrigues, FB;
Byrne, LM;
McColgan, P;
Robertson, N;
Tabrizi, SJ;
Zetterberg, H;
Wild, EJ;
(2016)
Cerebrospinal Fluid Inflammatory Biomarkers Reflect Clinical Severity in Huntington's Disease.
PLOS ONE
, 11
(9)
, Article e0163479. 10.1371/journal.pone.0163479.
|
|
Rodrigues, FB;
Duarte, GS;
Costa, J;
Ferreira, JJ;
Wild, EJ;
(2017)
Meta-research metrics matter: letter regarding article “indirect tolerability comparison of Deutetrabenazine and Tetrabenazine for Huntington disease”.
Journal of Clinical Movement Disorders
, 4
, Article 19. 10.1186/s40734-017-0067-x.
|
|
|
Rodrigues, FB;
Duarte, GS;
Costa, J;
Ferreira, JJ;
Wild, EJ;
(2017)
Tetrabenazine versus deutetrabenazine for Huntington's disease: twins or distant cousins?
Movement Disorders Clinical Practice
, 4
(4)
pp. 582-585.
10.1002/mdc3.12483.
|
|
Rodrigues, FB;
Ferreira, JJ;
Wild, EJ;
(2018)
Physician perception versus true efficacy of tetrabenazine for Huntington's disease.
Current Medical Research and Opinion
, 34
(9)
10.1080/03007995.2018.1490703.
|
|
Rodrigues, FB;
Wild, EJ;
(2020)
Huntington's Disease Clinical Trials Corner: April 2020.
Journal of Huntington's Disease
, 9
(2)
pp. 185-197.
10.3233/JHD-200002.
|
|
|
Rodrigues, FB;
Wild, EJ;
(2017)
Clinical Trials Corner: September 2017.
Journal of Huntington’s Disease
, 6
(3)
pp. 255-263.
10.3233/JHD-170262.
|
|
|
Rodrigues, FB;
Wild, EJ;
(2016)
Psychogenic non-epileptic seizures in early Huntington's disease.
Practical Neurology
10.1136/practneurol-2016-001423.
(In press).
|
|
Ross, CA;
Aylward, EH;
Wild, EJ;
Langbehn, DR;
Long, JD;
Warner, JH;
Scahill, RI;
... Tabrizi, SJ; + view all
(2014)
Huntington disease: natural history, biomarkers and prospects for therapeutics.
Nature Reviews Neurology
, 10
204- 216.
10.1038/nrneurol.2014.24.
|
|
|
Runne, H;
Kuhn, A;
Wild, EJ;
Pratyaksha, W;
Kristiansen, M;
Isaacs, JD;
Regulier, E;
... Luthi-Carter, R; + view all
(2007)
Analysis of potential transcriptomic biomarkers for Huntington's disease in peripheral blood.
Proceedings of the National Academy of Sciences
, 104
(36)
14424 - 14429.
10.1073/pnas.0703652104.
|
|
|
Saft, C;
Epplen, JT;
Wieczorek, S;
Landwehrmeyer, GB;
Roos, RA;
de Yebenes, JG;
Dose, M;
... Arning, L; + view all
(2011)
NMDA receptor gene variations as modifiers in Huntington disease: a replication study.
PLoS Currents Huntington Disease
, 3
, Article RRN1247. 10.1371/currents.RRN1247.
|
|
|
Sanchez, II;
Nguyen, TB;
England, WE;
Lim, RG;
Vu, AQ;
Miramontes, R;
Byrne, LM;
... Thompson, LM; + view all
(2021)
Huntington's disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization.
Journal of Clinical Investigation
, 131
(12)
, Article e140723. 10.1172/JCI140723.
|
|
Scahill, Rachael I;
Farag, Mena;
Murphy, Michael J;
Hobbs, Nicola Z;
Leocadi, Michela;
Langley, Christelle;
Knights, Harry;
... Tabrizi, Sarah J; + view all
(2025)
Somatic CAG repeat expansion in blood associates with biomarkers of neurodegeneration in Huntington's disease decades before clinical motor diagnosis.
Nature Medicine
10.1038/s41591-024-03424-6.
(In press).
|
|
|
Scahill, RI;
Wild, EJ;
Tabrizi, SJ;
(2012)
Biomarkers for Huntington's disease: an update.
Expert Opinion on Medical Diagnostics
, 6
(5)
371 - 375.
10.1517/17530059.2012.701205.
|
|
|
Scahill, RI;
Zeun, P;
Osborne-Crowley, K;
Johnson, EB;
Gregory, S;
Parker, C;
Lowe, J;
... Tabrizi, SJ; + view all
(2020)
Biological and clinical characteristics of gene carriers far from predicted onset in the Huntington's disease Young Adult Study (HD-YAS): a cross-sectional analysis.
The Lancet Neurology
, 19
(6)
pp. 502-512.
10.1016/S1474-4422(20)30143-5.
|
|
|
Soylu-Kucharz, R;
Sandelius, A;
Sjogren, M;
Blennow, K;
Wild, EJ;
Zetterberg, H;
Bjorkqvist, M;
(2017)
Neurofilament light protein in CSF and blood is associated with neurodegeneration and disease severity in Huntington's disease R6/2 mice.
Scientific Reports
, 7
, Article 14114. 10.1038/s41598-017-14179-1.
|
|
Tabrizi, SJ;
Flower, MD;
Ross, CA;
Wild, EJ;
(2020)
Huntington disease: new insights into molecular pathogenesis and therapeutic opportunities.
Nature Reviews Neurology
, 16
pp. 529-546.
10.1038/s41582-020-0389-4.
|
|
Tabrizi, SJ;
Leavitt, BR;
Landwehrmeyer, GB;
Wild, EJ;
Saft, C;
Barker, RA;
Blair, NF;
... Lane, RM; + view all
(2019)
Targeting Huntingtin Expression in Patients with Huntington's Disease.
The New England Journal of Medicine
, 380
pp. 2307-2316.
10.1056/NEJMoa1900907.
|
|
Taylor, R;
Salanio, D;
Stanton, JED;
Wild, E;
(2017)
Ghost Pills.
Annals of Internal Medicine
10.7326/L16-0376.
|
|
Tortelli, R;
Rodrigues, F;
Wild, E;
(2021)
The use of wearable/portable digital sensors in Huntington’s disease: a systematic review.
Parkinsonism & Related Disorders
10.1016/j.parkreldis.2021.01.006.
(In press).
|
|
Weiss, A;
Träger, U;
Wild, EJ;
Grueninger, S;
Farmer, R;
Landles, C;
Scahill, RI;
... Tabrizi, SJ; + view all
(2012)
Mutant huntingtin fragmentation in immune cells tracks Huntington's disease progression.
Journal of Clinical Investigation
, 122
(10)
3731 - 3736.
10.1172/JCI64565.
|
|
|
Wexler, A;
Wild, EJ;
Tabrizi, SJ;
(2016)
George Huntington: a legacy of inquiry, empathy and hope.
Brain
, 139
(8)
pp. 2326-2333.
10.1093/brain/aww165.
|
|
Wild, E;
(2005)
Deja vu in neurology.
Journal of Neurology
, 252
(1)
pp. 1-7.
10.1007/s00415-005-0677-3.
|
|
|
Wild, E;
Magnusson, A;
Lahiri, N;
Krus, U;
Orth, M;
Tabrizi, SJ;
Björkqvist, M;
(2011)
Abnormal peripheral chemokine profile in Huntington's disease.
PLoS Curr
, 1
10.1371/currents.RRN1231.
|
|
|
Wild, EJ;
(2016)
Huntington's disease: the most curable incurable brain disorder?
EBioMedicine
, 8
pp. 3-4.
10.1016/j.ebiom.2016.05.023.
|
|
Wild, EJ;
Boggio, R;
Langbehn, D;
Robertson, N;
Haider, S;
Miller, JR;
Zetterberg, H;
... Weiss, A; + view all
(2015)
Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients.
J Clin Invest
10.1172/JCI80743.
|
|
|
Wild, EJ;
Carroll, JB;
(2012)
HDBuzz: empowering patients through accessible education.
Trends in Molecular Medicine
, 18
(1)
1 - 3.
10.1016/j.molmed.2011.09.003.
|
|
|
Wild, EJ;
Mudanohwo, EE;
Sweeney, MG;
Schneider, SA;
Beck, J;
Bhatia, KP;
Rossor, MN;
... Tabrizi, SJ; + view all
(2008)
Huntington's disease phenocopies are clinically and genetically heterogeneous.
Movement Disorders
, 23
(5)
716 - 720.
10.1002/mds.21915.
|
|
|
Wild, EJ;
Tabrizi, SJ;
(2019)
One decade ago, one decade ahead in huntington's disease.
Movement Disorders
, 34
(10)
pp. 1434-1439.
10.1002/mds.27849.
|
|
Wild, EJ;
Tabrizi, SJ;
(2017)
Correction: Therapies targeting DNA and RNA in Huntington's disease (vol 16, pg 837, 2017).
[Corrigendum].
Lancet Neurology
, 16
(12)
p. 954.
10.1016/S1474-4422(17)30367-8.
|
|
Wild, EJ;
Tabrizi, SJ;
(2017)
Therapies targeting DNA and RNA in Huntington's disease.
The Lancet Neurology
, 16
(10)
pp. 837-847.
10.1016/S1474-4422(17)30280-6.
|
|
Wild, EJ;
Tabrizi, SJ;
(2014)
Targets for future clinical trials in Huntington's disease: What's in the pipeline?
Movement Disorders
, 29
(11)
pp. 1434-1445.
10.1002/mds.26007.
|
|
|
Wild, EJ;
Tabrizi, SJ;
(2007)
The differential diagnosis of chorea.
Practical Neurology
, 7
(6)
360 - 373.
10.1136/pn.2007.134585.
|
|
|
Yamamoto, Yumi;
Silber Baumann, Hanna E;
Bjornsson, Marcus;
Grimsey, Paul;
Hawellek, David J;
Anderson, Karen;
Leavitt, Blair R;
... Sanwald Ducray, Patricia; + view all
(2025)
Quantitative relationship between tominersen concentrations in cerebrospinal fluid and biomarker changes in Huntington's disease patients.
British Journal of Clinical Pharmacology
10.1002/bcp.70367.
(In press).
|
|
Zeun, P;
Scahill, R;
Tabrizi, S;
Wild, E;
(2019)
Fluid and Imaging Biomarkers for Huntington's Disease.
Molecular and Cellular Neuroscience
, 97
pp. 67-80.
10.1016/j.mcn.2019.02.004.
|
|
Zhen-Yi, AO;
Byrne, L;
Brogueira Rodrigues, F;
Tortelli, R;
Johnson, E;
Foiani, M;
Arridge, M;
... Wild, E; + view all
(2021)
Brain-derived neurotrophic factor in cerebrospinal fluid and plasma is not a biomarker for Huntington’s disease.
Scientific Reports
, 11
, Article 3481. 10.1038/s41598-021-83000-x.
|
|
|
Zuccato, C;
Marullo, M;
Vitali, B;
Tarditi, A;
Mariotti, C;
Valenza, M;
Lahiri, N;
... Cattaneo, E; + view all
(2011)
Brain-Derived Neurotrophic Factor in Patients with Huntington's Disease.
PLOS ONE
, 6
(8)
, Article e22966. 10.1371/journal.pone.0022966.
|
|
Book chapter
|
Rodrigues, FB;
Byrne, LM;
Wild, EJ;
(2018)
Biofluid Biomarkers in Huntington's Disease.
In: Precious, SV and Rosser, AE and Dunnett, SB, (eds.)
Huntington’s Disease.
(pp. 329-396).
Humana Press: New York, NY, USA.
|
|
Wild, EJ;
Tabrizi, S;
(2014)
Premanifest and early Huntington's disease.
In: Bates, G and Tabrizi, SJ and Jones, L, (eds.)
Huntington's Disease.
Oxford University Press: Oxford, UK.
|
Report
|
Wild, E;
Byrne, L;
Rodrigues, F;
(2015)
HD-CSF protocol.
(Studying cerebrospinal fluid to understand key CNS pathobiological targets in Huntington's disease
).
University College London (UCL): London, UK.
|
|
Working / discussion paper
|
Ou, ZYA;
Byrne, LM;
Rodrigues, FB;
Tortelli, R;
Johnson, EB;
Foiani, MS;
Arridge, M;
... Wild, EJ; + view all
(2020)
Brain-derived neurotrophic factor in cerebrospinal fluid and plasma is not a biomarker for Huntington's disease.
MedRxiv: Cold Spring Harbor, NY, USA.
|
|
Conference item
|
Rodrigues, FB;
Tabrizi, SJ;
Taylor, R;
Wild, EJ;
(2016)
The cost and value of a Huntington's Disease multidisciplinary team meeting.
Presented at: EHDN2016: 9th European Huntington's Disease Network Plenary Meeting 2016, The Hague, The Netherlands.
|
|
|
Tabrizi, SJ;
Leavitt, B;
Landwehrmeyer, B;
Wild, E;
Salt, C;
Barker, R;
Craufurd, D;
... HTT Rx CS1 study teams, .; + view all
(2018)
Effects of IONIS-HTTRX (RG6042) in Patients With Early Huntington's Disease, Results of the First Htt-lowering Drug Trial.
Presented at: EHDN Plenary Meeting, Vienna, Austria.
|
|
